CN104788447B - A kind of semi-synthesis method prepares the production technology of vincamine - Google Patents
A kind of semi-synthesis method prepares the production technology of vincamine Download PDFInfo
- Publication number
- CN104788447B CN104788447B CN201510188608.6A CN201510188608A CN104788447B CN 104788447 B CN104788447 B CN 104788447B CN 201510188608 A CN201510188608 A CN 201510188608A CN 104788447 B CN104788447 B CN 104788447B
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- CN
- China
- Prior art keywords
- vincamine
- acid
- production technology
- semi
- vincadifformine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
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Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201510188608.6A CN104788447B (en) | 2015-04-21 | 2015-04-21 | A kind of semi-synthesis method prepares the production technology of vincamine |
Applications Claiming Priority (1)
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CN201510188608.6A CN104788447B (en) | 2015-04-21 | 2015-04-21 | A kind of semi-synthesis method prepares the production technology of vincamine |
Publications (2)
Publication Number | Publication Date |
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CN104788447A CN104788447A (en) | 2015-07-22 |
CN104788447B true CN104788447B (en) | 2016-08-31 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN201510188608.6A Active CN104788447B (en) | 2015-04-21 | 2015-04-21 | A kind of semi-synthesis method prepares the production technology of vincamine |
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CN (1) | CN104788447B (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106749229B (en) * | 2016-12-20 | 2018-08-17 | 东北制药集团股份有限公司 | A kind of process for purification of pervone |
CN113321643B (en) * | 2021-06-17 | 2023-06-20 | 四川大学 | Intermediate, preparation method and application thereof in synthesizing vincamine |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE763730R (en) * | 1971-01-15 | 1971-08-02 | Omnium Chimique Sa | PROCESS FOR PREPARING NATURAL VINCAMINE FROM LATABERSONIN AND INDOLIC DERIVATIVES |
CH664153A5 (en) * | 1985-02-28 | 1988-02-15 | Arysearch Arylan Ag | PROCEDURE FOR THE PREPARATION OF THE VINCAMINA. |
CN102108082A (en) * | 2009-12-23 | 2011-06-29 | 广州斯威森科技有限公司 | Industrialized semisynthesis of medicine-vincamine for treating cerebral ischemia |
CN102040606B (en) * | 2011-01-26 | 2012-10-03 | 陕西嘉禾植物化工有限责任公司 | Synthetic method of vinpocetine |
CN102276599B (en) * | 2011-08-18 | 2012-10-17 | 张家口市格瑞高新技术有限公司 | Process for preparing vincamine by semisynthetic method |
CN103232452A (en) * | 2013-05-14 | 2013-08-07 | 彭学东 | Industrialized semi-synthesis process of vincamine |
CN103664941B (en) * | 2013-12-06 | 2015-12-02 | 湖南科源生物制品有限公司 | A kind of preparation method of vinpocetine analogue |
CN104327073B (en) * | 2014-10-16 | 2016-05-04 | 广州普星药业有限公司 | A kind of semi-synthetic production method of vinpocetine |
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2015
- 2015-04-21 CN CN201510188608.6A patent/CN104788447B/en active Active
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Publication number | Publication date |
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CN104788447A (en) | 2015-07-22 |
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Legal Events
Date | Code | Title | Description |
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C06 | Publication | ||
PB01 | Publication | ||
EXSB | Decision made by sipo to initiate substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: A production process of vinblastine by semi synthetic method Effective date of registration: 20210930 Granted publication date: 20160831 Pledgee: Agricultural Bank of China Limited Zhangjiagang branch Pledgor: ZHANG JIA GANG VINSCE BIO-PHARM Co.,Ltd. Registration number: Y2021320010400 |
|
PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
CP03 | Change of name, title or address |
Address after: No. 2, Nanjing Middle Road, Jiangsu Yangzijiang Chemical Industrial Park, Zhangjiagang Free Trade Zone, Suzhou City, Jiangsu Province, 215634 Patentee after: Wison Biomedical (Suzhou) Co.,Ltd. Address before: 215634 No. 2 Nanjing Middle Road, Yangtze River Chemical Industrial Park, Zhangjiagang Free Trade Zone, Suzhou City, Jiangsu Province Patentee before: Weisheng Biomedical (Suzhou) Co.,Ltd. Address after: 215634 No. 2 Nanjing Middle Road, Yangtze River Chemical Industrial Park, Zhangjiagang Free Trade Zone, Suzhou City, Jiangsu Province Patentee after: Weisheng Biomedical (Suzhou) Co.,Ltd. Address before: 215634 Floor 3, Building D, No. 7, Guangdong Road, Zhangjiagang Free Trade Zone, Suzhou, Jiangsu Province Patentee before: ZHANG JIA GANG VINSCE BIO-PHARM Co.,Ltd. |
|
CP03 | Change of name, title or address | ||
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20221031 Granted publication date: 20160831 Pledgee: Agricultural Bank of China Limited Zhangjiagang branch Pledgor: ZHANG JIA GANG VINSCE BIO-PHARM Co.,Ltd. Registration number: Y2021320010400 |
|
PC01 | Cancellation of the registration of the contract for pledge of patent right |