CN104771826B - It is enriched with the drainage tube of exfoliated tumor cells - Google Patents
It is enriched with the drainage tube of exfoliated tumor cells Download PDFInfo
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- CN104771826B CN104771826B CN201510230029.3A CN201510230029A CN104771826B CN 104771826 B CN104771826 B CN 104771826B CN 201510230029 A CN201510230029 A CN 201510230029A CN 104771826 B CN104771826 B CN 104771826B
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- drainage tube
- bending part
- flatbed
- seroperitoneum
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Abstract
The invention discloses a kind of drainage tubes for being enriched with exfoliated tumor cells, including drainage tube main body, one end that the drainage tube main body is located in splanchnocoel is provided with flatbed bending part, is provided with to deposit the groove of exfoliated tumor cells at the flatbed bending part step opposite with seroperitoneum flow direction.The present invention is located in vivo position in drainage tube and is arranged to bending shape structure, and groove is set at the step of corresponding seroperitoneum flow direction, it adds tumour cell and stops enriching machine meeting, can ensure tumour cell by when can by sedimentation absorption in pipe, improve tumour cell recall rate, failing to pinpoint a disease in diagnosis for tumprigenicity Pleural effusions effectively is avoided, is treated in advance for patient and reliable guarantee is provided.
Description
Technical field
The present invention relates to the field of medical instrument technology, particularly a kind of drainage tube for being used to drain Pleural effusions.
Background technology
Thoracic cavity and seroperitoneum are the frequently-occurring disease and common disease of clinical respiratory system and digestive system, and the common cause of disease has very
It is more, such as cardiovascular disease, hepatopathy, peritoneopathy, kidney trouble, dystrophia disease, the transfer of malignant tumour peritonaeum, ovarian neoplasm, knot
Tissue disease etc. is formed, disease forms pleural effusion and excessively becomes Pleural effusions.Pleural effusions inspection is used clinically for passing through inspection
The property of Pleural effusions come determine Pleural effusions formation the reason for and the cause of disease, directiveness is served to the treatment of clinical disease.
Pernicious Pleural effusions refer to that malignant tumour due to being happened at whole body or splanchnocoel or cancerous lesion cause thoracic cavity, abdominal cavity
The phenomenon that lamina visceralis pleuroperitoneum occurs diffusivity lesion and causes cavity fluids abnormal increase, therefore clinically in the chest and abdomen of extraction
It is to carry out the cause of disease to patient to determine and take the premise effectively treated in time that cancer cell is found in water.Pleural effusions are big under normal circumstances
There are about thousands of milliliters, and clinically often outwards extract the Pleural effusions censorship of 5 ~ 10ml at random with drainage tube；However, due to
Initial stage of cancer, cancer cell number is less, therefore is present with and fails to pinpoint a disease in diagnosis phenomenon, so that delay conditions of patients.
The content of the invention
The technical problem to be solved in the invention is to provide one kind and is applied in clinical medicine, is outwards extracted from splanchnocoel
The drainage tube of Pleural effusions can settle the tumour cell in Pleural effusions, to improve the recall rate of tumour cell.
In order to solve the above technical problems, the technical solution used in the present invention is as follows.
The drainage tube of exfoliated tumor cells is enriched with, including drainage tube main body, the drainage tube main body is located in splanchnocoel
One end is provided with flatbed bending part, is set at the flatbed bending part step opposite with seroperitoneum flow direction useful
In the groove of deposition exfoliated tumor cells.
The drainage tube of above-mentioned enrichment exfoliated tumor cells, the flatbed bending part are opposite with seroperitoneum flow direction
It is provided on step for adherent tumor cast-off cells and covers the adsorption layer of groove.
The drainage tube of above-mentioned enrichment exfoliated tumor cells is wrapped up on the inner wall of the drainage tube main body special with epithelial cell
Property antibody membrane.
As a result of above technical scheme, the invention technological progress is as follows.
The present invention is located in vivo position in drainage tube and is arranged to bending shape structure, and in corresponding seroperitoneum flow direction
Step at set groove, add tumour cell stop enriching machine meeting, can ensure tumour cell by when can by sedimentation suction
It is attached in pipe, improves tumour cell recall rate, effectively avoid failing to pinpoint a disease in diagnosis for tumprigenicity Pleural effusions, treat and provide reliably in advance for patient
Ensure.
Description of the drawings
Fig. 1 is the structural diagram of the present invention.
Wherein：1. drainage tube main body, 2. flatbed bending parts, 3. grooves.
In figure, arrow direction is seroperitoneum flow direction.
Specific embodiment
In order to which technical problems, technical solutions and advantages to be solved are more clearly understood, tie below
Accompanying drawings and embodiments are closed, the present invention will be described in detail.It should be noted that specific embodiment described herein is only used
To explain the present invention, it is not intended to limit the present invention.
The drainage tube of exfoliated tumor cells is enriched with, structure is as shown in Figure 1, including drainage tube main body 1, drainage tube main body 1
One end in splanchnocoel is provided with flatbed bending part 2, and flatbed bending part can set multilayer, be set altogether in the present embodiment
Three layers of flatbed bending part 2.
Fluted 3 are set at the step opposite with seroperitoneum flow direction of flatbed bending part 2, is taken off for depositing tumour
Fall cell, groove can be set up in parallel multiple, be respectively provided with two grooves 3 in the present embodiment at every layer of step.
Adsorption layer 3 is provided on the step opposite with seroperitoneum flow direction of flatbed bending part 2, adsorption layer 3 is used for
Adherent tumor cast-off cells.It containing volume ratio is 3 that adsorption layer in the present invention, which is,：Body fluid and curing agent mixture before 1 PDMS
Layer.
It is wrapped up on the inner wall of drainage tube main body 1 with epithelial cell specific antibody film.
When the present invention makes, one end platform for making type bending part for being located at first in drainage tube main body in splanchnocoel；Secondly,
Groove is set at the flatbed bending part step opposite with seroperitoneum flow direction；Then, flatbed bending part with
It is 3 that volume ratio is smeared on the opposite step in seroperitoneum flow direction：Body fluid and curing agent mixture before 1 PDMS, then will draw
Flow tube is put into 65 degrees Celsius of oven for solidifying three hours, forms adsorption layer；Finally, then by concentration it is the epithelium of 800-1500ug/ml
Cell-specific antibodies are poured into drainage tube, and are given 4 degrees Celsius of environment and preserved that can to form epithelium on drainage inside pipe wall thin
Born of the same parents' specific antibody film.
The present invention is in use, directly insert drainage tube one end with bending part in splanchnocoel, drainage tube is in splanchnocoel
In the built-in period, exfoliated tumor cells are deposited in groove and adsorb and inhaling during pleural effusion flows
On attached layer.After drainage tube taking-up, when detecting tumour cell to pathology department, pass through the groove of elution drainage tube bending part
Place, you can be collected into the hydrops containing more exfoliated tumor cells, substantially increase the recall rate of exfoliated tumor cells, avoid
Tumprigenicity Pleural effusions fail to pinpoint a disease in diagnosis the generation of phenomenon.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all originals in the present invention
Then with all any modification, equivalent and improvement made within spirit etc., it is included within protection scope of the present invention.
Claims (1)
1. the drainage tube of exfoliated tumor cells is enriched with, including drainage tube main body（1）, it is characterised in that：The drainage tube main body（1）
One end in splanchnocoel is provided with flatbed bending part（2）, the flatbed bending part（2）With seroperitoneum flow direction
It is provided with to deposit the groove of exfoliated tumor cells at opposite step（3）；
The flatbed bending part（2）It is provided on the step opposite with seroperitoneum flow direction and comes off carefully for adherent tumor
Born of the same parents simultaneously cover groove（3）Adsorption layer；
The drainage tube main body（1）Inner wall on wrap up in epithelial cell specific antibody film；
The production method of drainage tube is：
One end platform for making type bending part being located at first in drainage tube main body in splanchnocoel；
Secondly, groove is set at the flatbed bending part step opposite with seroperitoneum flow direction；
Then, it is 3 that volume ratio is smeared on the flatbed bending part step opposite with seroperitoneum flow direction：Before 1 PDMS
Body fluid and curing agent mixture, then drainage tube is put into 65 degrees Celsius of oven for solidifying three hours, form adsorption layer；
Finally, then by the epithelial cell specific antibody that concentration is 800-1500ug/ml pour into drainage tube, and it is Celsius to give 4
It spends environment and preserves and can form epithelial cell specific antibody film on drainage inside pipe wall.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510230029.3A CN104771826B (en) | 2015-05-08 | 2015-05-08 | It is enriched with the drainage tube of exfoliated tumor cells |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510230029.3A CN104771826B (en) | 2015-05-08 | 2015-05-08 | It is enriched with the drainage tube of exfoliated tumor cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104771826A CN104771826A (en) | 2015-07-15 |
| CN104771826B true CN104771826B (en) | 2018-05-25 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510230029.3A Active CN104771826B (en) | 2015-05-08 | 2015-05-08 | It is enriched with the drainage tube of exfoliated tumor cells |
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Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2561430Y (en) * | 2002-08-23 | 2003-07-23 | 庞德湘 | Multi-hole thoracic drainage pipe |
| CN201108445Y (en) * | 2007-06-15 | 2008-09-03 | 刘立昌 | Endometrium cast-off cells sampler |
| CN201631867U (en) * | 2010-03-11 | 2010-11-17 | 庄育田 | Disposable abdominocentesis drainage tube |
| CN201996960U (en) * | 2011-01-26 | 2011-10-05 | 德州学院 | Ascites drainage tube |
| JP2013031696A (en) * | 2006-12-13 | 2013-02-14 | Ethicon Endo Surgery Inc | Biopsy sample storing assembly |
| CN203074759U (en) * | 2012-05-31 | 2013-07-24 | 韩春勇 | Total alimentary canal tumor cell gatherer |
| CN203139354U (en) * | 2013-03-26 | 2013-08-21 | 薛信乐 | Novel ascites drainage puncture needle |
| CN203790424U (en) * | 2014-01-27 | 2014-08-27 | 苏州大学附属第一医院 | Chest drainage pipe |
| CN204563275U (en) * | 2015-05-08 | 2015-08-19 | 无锡市人民医院 | The drainage tube of enrich tumor exfoliative cyte |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000072908A1 (en) * | 1999-06-02 | 2000-12-07 | Microheart, Inc. | Devices and methods for delivering a drug |
-
2015
- 2015-05-08 CN CN201510230029.3A patent/CN104771826B/en active Active
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2561430Y (en) * | 2002-08-23 | 2003-07-23 | 庞德湘 | Multi-hole thoracic drainage pipe |
| JP2013031696A (en) * | 2006-12-13 | 2013-02-14 | Ethicon Endo Surgery Inc | Biopsy sample storing assembly |
| CN201108445Y (en) * | 2007-06-15 | 2008-09-03 | 刘立昌 | Endometrium cast-off cells sampler |
| CN201631867U (en) * | 2010-03-11 | 2010-11-17 | 庄育田 | Disposable abdominocentesis drainage tube |
| CN201996960U (en) * | 2011-01-26 | 2011-10-05 | 德州学院 | Ascites drainage tube |
| CN203074759U (en) * | 2012-05-31 | 2013-07-24 | 韩春勇 | Total alimentary canal tumor cell gatherer |
| CN203139354U (en) * | 2013-03-26 | 2013-08-21 | 薛信乐 | Novel ascites drainage puncture needle |
| CN203790424U (en) * | 2014-01-27 | 2014-08-27 | 苏州大学附属第一医院 | Chest drainage pipe |
| CN204563275U (en) * | 2015-05-08 | 2015-08-19 | 无锡市人民医院 | The drainage tube of enrich tumor exfoliative cyte |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104771826A (en) | 2015-07-15 |
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