CN104771255B - The implementation method of motor pattern is recognized based on cortex hemoglobin information - Google Patents
The implementation method of motor pattern is recognized based on cortex hemoglobin information Download PDFInfo
- Publication number
- CN104771255B CN104771255B CN201510010037.7A CN201510010037A CN104771255B CN 104771255 B CN104771255 B CN 104771255B CN 201510010037 A CN201510010037 A CN 201510010037A CN 104771255 B CN104771255 B CN 104771255B
- Authority
- CN
- China
- Prior art keywords
- motion
- motor
- cortex
- rate
- change
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
The invention discloses a kind of implementation method that motor pattern is recognized based on cortex hemoglobin information, subject autonomous control starting and end time under four kinds of motor patterns, for the rate of change of cortex HC, applied statistics analytical oxygen-containing statistical discrepancy with deoxyhemoglobin in each motion association region of cortex under different motor patterns, seat and two kinds of relative motion trends of up/down steps have been distinguished based on statistical nature;On this basis, the oxygen-containing and deoxyhemoglobin difference between each moving region of analysis cortex, specific motor pattern is determined with reference to both legs relative motion trend and new statistical nature.Using non-intrusion type NIRS technical notes human body cortex HC information, trained without environmental stimuli and early stage, it is few to test environment and subject's limitation;There is preferable room and time resolution ratio;Improve the intelligent of walk-aid equipment.
Description
Technical field
The present invention relates to a kind of implementation method that motor pattern is recognized based on cortex hemoglobin information, belong to brain machine and connect
Mouth direction.
Background technology
According to the 6th national census China total number of people and the Second China National Sample Survey on Disability, calculate
2010 year end China disabled person total numbers of persons and all kinds of, different grades of disabled number:Ratio wherein shared by physical disabilities is maximum
It is 29.08%.Additionally, China progresses into aging society, and 2012, national 60 years old and the people of above elderly population 193900000,
Account for the 14.3% of total population;Wherein 65 years old and the people of above population 127,140,000, account for the 9.4% of total population.According to scholarly forecast, arrive
The year two thousand twenty, China 60 years old and over-65s population proportion are respectively 16.23% and 11.30%;The year two thousand thirty is 22.34% He
15.21%;The year two thousand forty is 25% and 20%.Be can be seen that during to the year two thousand thirty from above-mentioned data, China will be into " super senior type " society
Meeting.And to the year two thousand fifty, the population of more than 60 years old is up to 400,000,000 or so, account for total population proportion will more than 25.2%,
When, just there is 1 the elderly in the middle of every 4 Chinese, China will turn into the country of height aging.With the old-age group of population structure
Change, have the elderly patient of dyskinesia more and more, be that these disabled persons for having dyskinesia and the elderly are equipped with
Walk-aid equipment is to assist them to realize independent ambulation, return the Main Means of mainstream of society again.
In order to improve the intelligent of the equipment of helping the disabled of helping the elderly, many research institutions are devoted to research and development and are based on brain-computer interface technology
New product of helping the disabled of helping the elderly.However, also there is following subject matter in current brain-computer interface technology:
(1) the brain-computer interface technology of implanted or semi-implantation type has been achieved for breakthrough, but by micro electric
In the cerebral gray matter of pole implantation experimenter or on subdural cerebral cortex, immune response and callus may be triggered;
But also deposit after the implantation psychology and ethics problem, extensive use is still unsuitable at present.
(2) the brain information measuring technology of non-intrusion type includes electroencephalogram (EEG), magneticencephalogram (MEG), functional magnetic resonance imaging
The technologies such as image (fMRI), Squares Framework for PET Image (PET) and near infrared spectrum cerebral function imaging (NIRS);Wherein fMRI
Spatial resolution with PET technologies is higher, but temporal resolution is low, and body is often confined to inactive state in test process,
There is very big binding character;The application requirement of MEG is fully shielded to external magnetic field;So presently mainly EEG and NIRS skills
Art is applied to help the elderly in the research and development of products help the disabled.But in the brain-computer interface system research based on EEG signal, conventional base
There is provided to stimulate and in VEP (VEP) and the extra stimulating apparatus of event related potential (P300) this two classes method needs
Produce Evoked ptential, and depend on certain of people to feel that such as vision forces experimenter synchronous with outside stimulus, due to it is long when
Between operation easily cause visual fatigue or reduce P300 current potentials conspicuousness, the corresponding brain-computer interface operating time should not mistake
It is long.And spontaneous brain electricity figure again relies on the spontaneous cerebration of user, only special thinking processes could produce detectable
Cerebration, it is necessary to experimenter carry out it is substantial amounts of training come produce AD HOC brain electricity, influenceed larger by subjective factor.Therefore,
Experiment is more to be completed, it is necessary to experimenter focuses under given conditions, and the action of realization is simply limited, lacks naturality with spirit
Activity, practicality is not strong.The temporal resolution of NIRS technologies is higher than fMRI, lower than EEG;Spatial resolution is higher than EEG, compares fMRI
It is low;If carrying out pattern-recognition using NIRS technical testings brain biological information, be conducive to dynamically being measured under natural environment, but it is raw
The extraction rate of thing information is relatively low.
The content of the invention
In order to overcome drawbacks described above, a kind of flexibility of present invention offer is higher, practicality is stronger, action is more rich and natural
Based on cortex hemoglobin information recognize motor pattern implementation method, the method be used for walk-aid equipment control help to carry
Walk-aid equipment high it is intelligent.
Motor pattern in this patent content, lower limb motion mode is referred both to without specified otherwise, is repeated no more in text.
And, mark means " mark " that pvalues means " significance " in a particular application for simplicity of exposition in text
Understand, pvalues is abbreviated as p.
The technical scheme that is used to solve its technical problem of the present invention is:One kind is based on cortex hemoglobin information
The implementation method of motor pattern is recognized, is comprised the following steps:
(1) set four kinds of motor patterns, i.e., upper and lower step and rise, sit:It is non-that the upper and lower step movement is also called both legs
Mirror image periodic motion;Described, sit motion be also called both legs specular motion;Subject is autonomous under four kinds of motor patterns
The starting of control motion and the time of termination;
(2) the cortex motion association region of test is divided into the preceding motor area in left side, the preceding motor area in right side, motion auxiliary
Area, five associated regions in preceding motion auxiliary region and primary motor area;
(3) application near infrared light cerebral function imaging equipment to subject, transport by corticocerebral each under four kinds of motor patterns
The HC of dynamic associated region is recorded;
(4) test subject different hemoglobin kinds in each motion association region of cerebral cortex under four kinds of motor patterns
The concentration information of class;
(5) subject wears test headgear, and tests a pair of the motion association region 1 of cortex five of headgear and head
That answers places;
(6) responsiveness of the subject in daily life grasps test speed, and the first group task is done first:Rise,
Seat is acted, subject according to it is daily, sit and be accustomed to and speed completes This move;And be repeated four times, what is acted every time opens
Begin and terminate by subject's autonomous control, experimental implementation person is responsible for mark;
(7) responsiveness of the subject in daily life grasps test speed, then does the second group task:Upper,
Get out of a predicament or an embarrassing situation action, subject according to it is daily, sit custom and speed completes This move;And be repeated four times, action every time
Beginning and terminate being controlled by subject oneself, experimental implementation person is responsible for mark;
(8) based on the hemoglobin data tested, applied statistics analytic approach is big under different motor patterns to analyze
The statistical discrepancy of oxygen-containing hemoglobin and deoxyhemoglobin rate of change in each motion association region of cortex;0.5 is made
It is significance (pvalues), i.e. the threshold value of p value;When p≤0.05, statistical discrepancy significance is represented;When p >=0.5
When, represent statistics difference nonsignificance;
(9) on the basis of step (8), oxygenated blood red eggs between each cerebral cortex motion association region are analyzed respectively
The difference of white rate of change and the difference of deoxyhemoglobin rate of change;
(10) difference condition analyzed according to step (8) and (9) is identified to the motor pattern of subject;
(11) in the preceding motor area in right side:If between oxygen-containing hemoglobin rate of change and deoxyhemoglobin rate of change
With significant statistical discrepancy, then it is assumed that be the non-mirror image cycle repeating motion of both legs;
If there is no statistical discrepancy, Er Qietong between oxygen-containing hemoglobin rate of change and deoxyhemoglobin rate of change
Meter result p >=0.5, then it is assumed that be the motion of both legs specular;
(12) for the non-mirror image cycle repeating motion trend of both legs, in the preceding motor area in left side:If oxygen-containing hemoglobin becomes
Changing has significant statistical discrepancy between speed and deoxyhemoglobin rate of change, then be judged as YES ' getting out of a predicament or an embarrassing situation ' motion mould
Formula;
If there is no statistical discrepancy between oxygen-containing hemoglobin rate of change and deoxyhemoglobin rate of change, and p >=
0.5, then it is judged as ' top bar ' motor pattern;
(13) for both legs specular movement tendency, if the deoxyhemoglobin rate of change of each moving region it
Between have significant difference, then be judged as ' sitting down ' motor pattern;
If there is no notable difference, and p >=0.5 between the deoxyhemoglobin rate of change of each moving region, then sentence
It is ' standing up ' motor pattern to break.
As a further improvement on the present invention, in step (2):The preceding motor area in the preceding motor area in left side and right side is primarily involved in
Motion control and the preparation of stance adjustment;Motion auxiliary region is primarily involved in motor behavior plan and double limbs coordination of tasks
Control;Preceding motion auxiliary region is primarily involved in motor behavior plan;Primary motor area is mainly responsible for providing motion control commands.
As a further improvement on the present invention, model Tianjin island FOIRE- of described near infrared light cerebral function imaging equipment
3000, the initial data that it is tested retains the frequency content between 0.02~0.06HZ by bandpass filtering, and its effect is filter
The low frequency physiological signal noises such as the high-frequency noise and pulse introduced during removing test, cutaneous respiration.
As a further improvement on the present invention, the near infrared light cerebral function imaging equipment has 8 pairs of transmittings and receiving terminal,
The distance between each pair transmitting and receiving terminal are 3cm;And 24 path informations are surveyed by 8 pairs of transmittings and receiving terminal
Examination;The concentration letter of oxygen-containing hemoglobin, deoxyhemoglobin and total hemoglobin in each path record human body motion process
Breath.
As a further improvement on the present invention, the side that the near infrared light cerebral function imaging equipment is received using time division emission
Method, the cycle sampled during its 24 path information of test is 130ms;And its MTD is 2~3cm under cerebral cortex.
As a further improvement on the present invention, in step (7), the ladder of step is 4 ranks, and step is placed on near-infrared
The side of light cerebral function imaging equipment, subject returns original position and prepares iterative task next time after getting out of a predicament or an embarrassing situation.
The beneficial effects of the invention are as follows:
(1) heart of intrusive mood brain-computer interface technology initiation is solved using the NIRS brain technologies for information acquisition of non-intrusion type
Reason and ethics problem, it is possible to tested during Large Amplitude Motion is carried out, it is not necessary to which environmental stimuli and a large amount of early stages are trained;
(2) carry out test in motion process, be that recognizing model of movement result should in walk-aid equipment control
With premise, the autonomous control of motion causes to obtain Cerebral cortex biological information under the Nature condition of cognitive activities, increased motion
The practical value of pattern-recognition;
(3) the rate of change identification motor pattern based on cortex HC, improves recognition rate, reduces brain
Blood oxygenation information lags behind the negative effect of cognitive activities, is conducive to quick mode to recognize, to provide control to walk-aid equipment in time
Information has established important early stage basis;
(4) based on statistical analysis difference identification motor pattern, the threshold information of blood oxygen concentration is not provided with, is reduced by individual
The erroneous judgement that body difference causes;
(5) based on statistical analysis difference identification motor pattern, only using first three sampled data of initial time, successively divide
The influence statistical discrepancy of different factor pair blood oxygen protein rate of changes is analysed, specific motor pattern is differentiated based on statistical discrepancy value,
Small data quantity and simple recognition methods greatly reduce pattern recognition period, are conducive to referring to for walk-aid equipment provides control in time
Order.
To sum up, using the Cerebral cortex hemoglobin information during non-intrusion type NIRS technical notes human motions, independently
Control motion is trained without environmental stimuli and early stage, few to test environment and subject's limitation;In the natural feelings of cognitive activities
Support to measure for a long time under scape, it is not necessary to largely trained, there is preferable room and time resolution ratio;Simultaneously will
Recognizing model of movement is blended with motion control, can improve the intelligent of walk-aid equipment, makes it in brain-computer interface application field
With bigger advantage.
Brief description of the drawings
Fig. 1 is that the present invention acts the motion timing diagram sat under motor pattern;
Fig. 2 is the motion timing diagram under up/down steps motor pattern of the present invention;
Fig. 3 is cortex motion association domain test passage distribution map of the present invention;
Fig. 4 is the statistics of four kinds of motor patterns of the invention different hemoglobin species rate of changes in the preceding motor area in right side
Difference;
Fig. 5 is the system of different hemoglobin species rate of changes of the four kinds of motor patterns of the invention in the preceding motor area in left side
Meter difference;
Fig. 6 is the system of the interregional deoxyhemoglobin rate of change of each motion association under four kinds of motor patterns of the invention
Meter difference;
Fig. 7 is the main effect statistics of under various motor patterns ' hemoglobin species ' of the invention;
Wherein:1a, the preceding motor area in left side, 2a, the preceding motor area in right side, 3a, preceding motion auxiliary region, 4a, motion auxiliary region,
5a, primary motor area.
Specific embodiment
The present invention will be further elaborated below in conjunction with the accompanying drawings.
First, some explanations are done to some marks in Figure of description respectively:
TA:Sit down;TB:Stand up;rest:Rest;Ta:Top bar;Tb:Get out of a predicament or an embarrassing situation;Tc:Retreat;rest:Rest;It is S1, de-
Oxygen hemoglobin;S2, oxygen-containing hemoglobin;* the rate of change of oxygen-containing hemoglobin and deoxyhemoglobin is represented with ﹡ marks
Between have statistical discrepancy.
As shown in Figures 1 to 7, a kind of implementation method that motor pattern is recognized based on cortex hemoglobin information, including
Following steps:
(1)) set four kinds of motor patterns, i.e., upper and lower step and rise, sit:It is non-that the upper and lower step movement is also called both legs
Mirror image periodic motion;Described, sit motion be also called both legs specular motion;Subject is autonomous under four kinds of motor patterns
The starting of control motion and the time of termination;
(2) the cortex motion association region of test is divided into the preceding motor area in left side, the preceding motor area in right side, motion auxiliary
Area, five associated regions in preceding motion auxiliary region and primary motor area;The preceding motor area in the preceding motor area in left side and right side is primarily involved in fortune
Dynamic control and the preparation of stance adjustment;Motion auxiliary region is primarily involved in motor behavior plan and double limbs coordination of tasks controls
System;Preceding motion auxiliary region is primarily involved in motor behavior plan;Primary motor area is mainly responsible for providing motion control commands;
(3) application near infrared light cerebral function imaging equipment to subject, transport by corticocerebral each under four kinds of motor patterns
The HC of dynamic associated region is recorded;Model Tianjin island FOIRE- of near infrared light cerebral function imaging equipment
3000;
(4) test subject different hemoglobin kinds in each motion association region of cerebral cortex under four kinds of motor patterns
The concentration information of class;
(5) subject wears test headgear, and tests a pair of the motion association region 1 of cortex five of headgear and head
That answers places;
(6) responsiveness of the subject in daily life grasps test speed, and the first group task is done first:Rise,
Seat is acted, subject according to it is daily, sit and be accustomed to and speed completes This move;And be repeated four times, what is acted every time opens
Begin and terminate by subject's autonomous control, experimental implementation person is responsible for marking mark;
(7) responsiveness of the subject in daily life grasps test speed, then does the second group task:Upper,
Get out of a predicament or an embarrassing situation action, subject according to it is daily, sit custom and speed completes This move;And be repeated four times, action every time
Beginning and terminate by subject's autonomous control, experimental implementation person be responsible for mark mark;The ladder of step is 4 ranks, and step
The side of near infrared light cerebral function imaging equipment is placed on, because fiber lengths are limited (2 meters), if tested turning round is carried out next time
Repeat to test, optical fiber traction headgear can cause the headgear to have displacement overhead, introduce test noise, and the region of test access is determined
Position can be greatly affected, while sense of discomfort also can be increased to tested, so subject returns starting after getting out of a predicament or an embarrassing situation in experiment
Position prepares iterative task next time, but " fall back " mode" puts aside during analysis;
(8) based on the hemoglobin data tested, applied statistics analytic approach is big under different motor patterns to analyze
The statistical discrepancy of oxygen-containing hemoglobin and deoxyhemoglobin rate of change in each motion association region of cortex;0.5 is made
Be pvalues, i.e. the threshold value of p value;When p≤0.05, statistical discrepancy significance is represented;When p >=0.5, statistics is represented
Difference nonsignificance;
(9) on the basis of step (8), oxygenated blood red eggs between each cerebral cortex motion association region are analyzed respectively
The difference of white rate of change and the difference of deoxyhemoglobin rate of change;
(10) difference condition analyzed according to step (8) and (9) is identified come the motor pattern to subject;
(11) in the preceding motor area in right side:If between oxygen-containing hemoglobin rate of change and deoxyhemoglobin rate of change
With significant statistical discrepancy, then it is assumed that be the non-mirror image cycle repeating motion of both legs;
If there is no statistical discrepancy, Er Qietong between oxygen-containing hemoglobin rate of change and deoxyhemoglobin rate of change
Meter result p >=0.5, then it is assumed that be the motion of both legs specular;
(12) for the non-mirror image cycle repeating motion trend of both legs, in the preceding motor area in left side:If oxygen-containing hemoglobin becomes
Changing has significant statistical discrepancy between speed and deoxyhemoglobin rate of change, then be judged as YES ' getting out of a predicament or an embarrassing situation ' motion mould
Formula;
If there is no statistical discrepancy between oxygen-containing hemoglobin rate of change and deoxyhemoglobin rate of change, and p >=
0.5, then it is judged as ' top bar ' motor pattern;
(13) for both legs specular movement tendency, if the deoxyhemoglobin rate of change of each moving region it
Between have significant difference, then be judged as ' sitting down ' motor pattern;
If there is no notable difference, and p >=0.5 between the deoxyhemoglobin rate of change of each moving region, then sentence
It is ' standing up ' motor pattern to break.
In each above-mentioned step, the near infrared light cerebral function imaging equipment has 8 pairs of transmittings and receiving terminal, each pair
The distance between transmitting and receiving terminal are 3cm;And 24 path informations are tested by 8 pairs of transmittings and receiving terminal;Often
The concentration information of oxygen-containing hemoglobin, deoxyhemoglobin and total hemoglobin in one path record human body motion process, by
In the method that near infrared light cerebral function imaging equipment is received using time division emission, so the week sampled during its 24 path information of test
Phase is 130ms;And its MTD is 2~3cm under cerebral cortex, the initial data that it is tested is retained by bandpass filtering
Frequency content between 0.02~0.06HZ, its effect is the high-frequency noise and pulse introduced during filtering out test, skin
The low frequency physiological signal noises such as breathing.
Using the HC information in 8 pairs of 4 × 4 regions of transmitter and receiver test in experiment.
Statistical analysis technique and mode discrimination method are further analyzed below:
First, using ternary method of analysis of variance (ANOVA3) analyze ' four kinds of motor patterns ', ' hemoglobin species ' and ' brain skin
Layer motion association region ' influence to hemoglobin rate of change;As p value (pvalues)≤0.05 for obtaining, it is believed that difference
With statistical significance:
(1) if ' four kinds of motor patterns ' and the interaction of ' hemoglobin species ' there is statistical significance, further divide
Analyse the main effect of under various motor patterns ' hemoglobin species ';Then respectively for each cortex motion association region point
Analyse whether the rate of change of oxygen-containing hemoglobin has statistics with the rate of change of deoxyhemoglobin under various motor patterns
Difference;
On this basis, the main effect under various motor patterns ' cortex motion association region ' is further analyzed;So
Analyze the rate of change of oxygen-containing hemoglobin with each motion association region or the change speed of deoxyhemoglobin respectively afterwards
Whether rate has statistical discrepancy under various motor patterns;Corresponding statistic analysis result is as follows:
' four kinds of motor patterns ' and the interaction of ' hemoglobin species ' there is obvious statistical discrepancy, i.e. p=
0.021, the main effect statistics of ' hemoglobin species ' is as shown in Figure 7 under various motor patterns:Transported wherein before left side
Dynamic area (PMCL) and the preceding motor area in right side (PMCR), both oxygen-containing hemoglobin rate of change and deoxyhemoglobin rate of change
Between difference between various motor patterns have visibly different sign;
As shown in Fig. 4, Fig. 5 and Fig. 7:In the preceding motor area in right side (PMCR), two under top bar and motor pattern of getting out of a predicament or an embarrassing situation
There is very significant statistical discrepancy, p=0.001 during top bar, p=0.000 when getting out of a predicament or an embarrassing situation between person;Rise, sit motor pattern
Under difference between the two it is not notable, p=0.836 when standing up, p=0.914 when sitting down;In the preceding motor area in left side (PMCL), under
There is very significant statistical discrepancy, p=0.008 when getting out of a predicament or an embarrassing situation, top bar and a seat fortune between the two under step movement pattern
Difference under dynamic model formula between the two is not notable, i.e., top bar when p=0.601, p=0.293 when standing up, p=when sitting down
0.932;The p value with statistical significance has embodied in the analysis chart of Fig. 4 and Fig. 5 in above-mentioned data;Other are not
P value with statistical significance is expressly recited in the figure 7, is not just being listed in Fig. 4 and Fig. 5, for clarity.
However, under motion auxiliary region (SMA) and preceding motion auxiliary region (Pre-SMA), oxygenated blood under various motor patterns
Lactoferrin rate of change generally with deoxyhemoglobin rate of change more statistical discrepancy;It is various at primary motor area (SMC)
Oxygen-containing hemoglobin rate of change and the generally no statistical discrepancy of deoxyhemoglobin rate of change under motor pattern;
(2) as shown in fig. 6, under various motor patterns, each interregional oxygen-containing hemoglobin rate of change is without obvious
Statistical discrepancy;In motor pattern of sitting down, each interregional deoxyhemoglobin rate of change is respectively provided with the statistical discrepancy of wire harness,
That is p=0.024, and in the other mode of movement, each interregional deoxyhemoglobin rate of change is without statistical discrepancy.
2nd, mode discrimination method:
(1) in the preceding motor area in right side, if between oxygen-containing hemoglobin rate of change and deoxyhemoglobin rate of change
With significant statistical discrepancy, i.e. p≤0.05, then it is assumed that be the non-mirror image cycle repeating motion of both legs;If oxygen-containing hemoglobin
There is no statistical discrepancy, and statistics p >=0.5 between rate of change and deoxyhemoglobin rate of change, then it is assumed that be double
Leg specular is moved;If the test data of some passages is placed doped with noise or headgear has little deviation, may
But the p value that analysis result can be caused without obvious statistical discrepancy counted has relatively small, so threshold of the selection 0.5 as p value
Value is reducing erroneous judgement.
(2) for the non-mirror image cycle repeating motion trend of both legs, in the preceding motor area in left side, if oxygen-containing hemoglobin changes
There is significant statistical discrepancy between speed and deoxyhemoglobin rate of change, be then judged as YES ' getting out of a predicament or an embarrassing situation ' motor pattern,
Else if p >=0.5, then be judged as ' top bar ' motor pattern;
(3) for both legs specular movement tendency, if the deoxyhemoglobin rate of change of each moving region it
Between have significant difference, then be judged as ' sitting down ' motor pattern, if the deoxyhemoglobin rate of change of each moving region it
Between there is no notable difference, and p >=0.5 item is judged as ' standing up ' motor pattern.
Using the Cerebral cortex hemoglobin information during non-intrusion type NIRS technical notes human motions, autonomous control fortune
It is dynamic to be trained without environmental stimuli and early stage, it is few to test environment and subject's limitation;Propped up under the Nature condition of cognitive activities
Hold measurement for a long time, it is not necessary to largely trained, there is preferable room and time resolution ratio;Mould will be moved simultaneously
Formula identification is blended with motion control, improves the intelligent of walk-aid equipment, it is had in brain-computer interface application field very big
Advantage.
Claims (6)
1. it is a kind of based on cortex hemoglobin information recognize motor pattern implementation method, it is characterised in that:Including following step
Suddenly:
(1) set four kinds of motor patterns, i.e., upper and lower step and rise, sit:The upper and lower step movement is also called the non-mirror image of both legs
Periodic motion;Described, sit motion be also called both legs specular motion;Subject's autonomous control under four kinds of motor patterns
The starting of motion and the time of termination;
(2) the cortex motion association region of test is divided into the preceding motor area in left side, the preceding motor area in right side, motion auxiliary region, preceding
Motion five associated regions in auxiliary region and primary motor area;
(3) application near infrared light cerebral function imaging equipment to subject, close by corticocerebral each motion under four kinds of motor patterns
The HC for joining region is recorded;
(4) test subject different hemoglobin species in each motion association region of cerebral cortex under four kinds of motor patterns
Concentration information;
(5) subject wears test headgear, and test headgear is one-to-one with five motion association regions of cortex of head
Place;
(6) responsiveness of the subject in daily life grasps test speed, and the first group task is done first:Rise, sit dynamic
Make, subject according to it is daily, sit and be accustomed to and speed completes This move;And be repeated four times, every time action beginning and
Terminate by subject's autonomous control, experimental implementation person is responsible for mark;
(7) responsiveness of the subject in daily life grasps test speed, then does the second group task:Upper and lower
Rank acts, subject according to it is daily, sit and be accustomed to and speed completes This move;And be repeated four times, what is acted every time opens
Begin and terminate to be controlled by subject oneself, experimental implementation person is responsible for mark;
(8) based on the hemoglobin data tested, applied statistics analytic approach analyzes the brain skin under different motor patterns
The rate of change statistical discrepancy of oxygen-containing hemoglobin and deoxyhemoglobin in each motion association region of layer;Using 0.5 as aobvious
Work property level, the i.e. threshold value of significance value;When significance≤0.05, statistical discrepancy significance is represented;When
During significance >=0.5, statistics difference nonsignificance is represented;
(9) on the basis of step (8), oxygen-containing hemoglobin becomes between each cerebral cortex motion association region is analyzed respectively
Change the difference of speed and the difference of deoxyhemoglobin rate of change;
(10) difference condition analyzed according to step (8) and (9) is identified to the motor pattern of subject;
(11) in the preceding motor area in right side:If had between oxygen-containing hemoglobin rate of change and deoxyhemoglobin rate of change
Significant statistical discrepancy, then it is assumed that be the non-mirror image cycle repeating motion of both legs;
If there is no statistical discrepancy between oxygen-containing hemoglobin rate of change and deoxyhemoglobin rate of change, and statistics knot
Fruit significance >=0.5, then it is assumed that be the motion of both legs specular;
(12) for the non-mirror image cycle repeating motion trend of both legs, in the preceding motor area in left side:If oxygen-containing hemoglobin change speed
There is significant statistical discrepancy between rate and deoxyhemoglobin rate of change, be then judged as YES ' getting out of a predicament or an embarrassing situation ' motor pattern;
If there is no statistical discrepancy between oxygen-containing hemoglobin rate of change and deoxyhemoglobin rate of change, and conspicuousness water
Flat >=0.5, then it is judged as ' top bar ' motor pattern;
(13) for both legs specular movement tendency, if had between the deoxyhemoglobin rate of change of each moving region
There were significant differences, then be judged as ' sitting down ' motor pattern;
If there is no notable difference, and significance >=0.5 between the deoxyhemoglobin rate of change of each moving region,
Then it is judged as ' standing up ' motor pattern.
2. it is according to claim 1 based on cortex hemoglobin information recognize motor pattern implementation method, its feature
It is:In step (2):The preceding motor area in the preceding motor area in left side and right side is primarily involved in the beam worker of motion control and stance adjustment
Make;Motion auxiliary region is primarily involved in motor behavior plan and the control of double limbs coordination of tasks;Preceding motion auxiliary region is primarily involved in
Motor behavior plan;Primary motor area is mainly responsible for providing motion control commands.
3. the implementation method that motor pattern is recognized based on cortex hemoglobin information according to claim 1 and 2, it is special
Levy and be:The model FOIRE-3000 of described near infrared light cerebral function imaging equipment, its initial data tested passes through
Bandpass filtering retains the frequency content between 0.02~0.06HZ.
4. it is according to claim 3 based on cortex hemoglobin information recognize motor pattern implementation method, its feature
It is:The near infrared light cerebral function imaging equipment have 8 pairs transmitting and receiving terminal, each pair transmitting and receiving terminal between away from
From being 3cm;And 24 path informations are tested by 8 pairs of transmittings and receiving terminal;Each path records human body motion process
In oxygen-containing hemoglobin, deoxyhemoglobin and total hemoglobin concentration information.
5. it is according to claim 4 based on cortex hemoglobin information recognize motor pattern implementation method, its feature
It is:The method that the near infrared light cerebral function imaging equipment is received using time division emission, samples during its 24 path information of test
Cycle be 130ms;And its MTD is 2~3cm under cerebral cortex.
6. it is according to claim 1 based on cortex hemoglobin information recognize motor pattern implementation method, its feature
It is:In step (7), the ladder of step is 4 ranks, and step is placed on the side of near infrared light cerebral function imaging equipment, receives
Examination person returns original position and prepares iterative task next time after getting out of a predicament or an embarrassing situation.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510010037.7A CN104771255B (en) | 2015-01-06 | 2015-01-06 | The implementation method of motor pattern is recognized based on cortex hemoglobin information |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510010037.7A CN104771255B (en) | 2015-01-06 | 2015-01-06 | The implementation method of motor pattern is recognized based on cortex hemoglobin information |
Publications (2)
Publication Number | Publication Date |
---|---|
CN104771255A CN104771255A (en) | 2015-07-15 |
CN104771255B true CN104771255B (en) | 2017-06-06 |
Family
ID=53613252
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201510010037.7A Active CN104771255B (en) | 2015-01-06 | 2015-01-06 | The implementation method of motor pattern is recognized based on cortex hemoglobin information |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN104771255B (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107019516B (en) * | 2017-03-31 | 2020-11-10 | 北京心灵方舟科技发展有限公司 | Method and device for suppressing near-infrared noise and detection equipment |
CN107595295B (en) * | 2017-06-09 | 2019-10-29 | 苏州大学 | A kind of lower extremity movement resistive state recognition methods based on brain hemoglobin information |
CN107478637B (en) * | 2017-07-07 | 2021-04-30 | 复旦大学 | Rapid label-free imaging method for distinguishing normal hemoglobin from ferrihemoglobin |
CN107563298B (en) * | 2017-08-08 | 2022-02-22 | 苏州大学 | Method for identifying squatting and walking state of imagination movement stage based on brain hemoglobin information |
CN108056777A (en) * | 2017-10-31 | 2018-05-22 | 北京心灵方舟科技发展有限公司 | Measure the device of oxygen-containing hemoglobin and deoxyhemoglobin and Brian Imaging equipment |
CN108932403B (en) * | 2018-07-02 | 2021-09-14 | 苏州大学 | Brain hemoglobin information-based resting state and movement state identification method |
CN109710065B (en) * | 2018-12-18 | 2021-12-28 | 苏州大学 | Method for recognizing walking regulation intention based on brain hemoglobin information |
CN117679025B (en) * | 2024-01-31 | 2024-05-03 | 北京航空航天大学 | Detection method, system and medium for detecting blood oxygen information of neuromuscular |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6606510B2 (en) * | 2000-08-31 | 2003-08-12 | Mallinckrodt Inc. | Oximeter sensor with digital memory encoding patient data |
US7890153B2 (en) * | 2006-09-28 | 2011-02-15 | Nellcor Puritan Bennett Llc | System and method for mitigating interference in pulse oximetry |
US8251903B2 (en) * | 2007-10-25 | 2012-08-28 | Valencell, Inc. | Noninvasive physiological analysis using excitation-sensor modules and related devices and methods |
SG191880A1 (en) * | 2011-01-19 | 2013-08-30 | Univ California | Apparatus, systems, and methods for tissue oximetry and perfusion imaging |
CN104224466A (en) * | 2014-09-25 | 2014-12-24 | 桂林电子科技大学 | Wheelchair control system based on detection of brain near-infrared function information |
-
2015
- 2015-01-06 CN CN201510010037.7A patent/CN104771255B/en active Active
Also Published As
Publication number | Publication date |
---|---|
CN104771255A (en) | 2015-07-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN104771255B (en) | The implementation method of motor pattern is recognized based on cortex hemoglobin information | |
He et al. | Brain–computer interfaces | |
Blankertz et al. | The Berlin Brain-Computer Interface: Accurate performance from first-session in BCI-naive subjects | |
Rak et al. | Brain-computer interface as measurement and control system the review paper | |
Brunner et al. | Improved signal processing approaches in an offline simulation of a hybrid brain–computer interface | |
Zhai et al. | Stress Recognition Using Non-invasive Technology. | |
CN104978035B (en) | Brain machine interface system and its implementation based on body-sensing electric stimulus inducing P300 | |
US20190343457A1 (en) | Pain assessment method and apparatus for patients unable to self-report pain | |
KR20150098607A (en) | Configuration and spatial placement of frontal electrode sensors to detect physiological signals | |
Houck et al. | Through a glass darkly: some insights on change talk via magnetoencephalography. | |
Major et al. | A survey of brain computer interfaces and their applications | |
CN109173063A (en) | A kind of the transcranial magnetic stimulation system and transcranial magnetic stimulation method of 3D scanning | |
CN106901751A (en) | A kind of recognition methods of the speed movement status based on brain hemoglobin information | |
CN115349873A (en) | Closed-loop brain function strengthening training device and method based on brain-computer interface system | |
Sarraf et al. | Brain–computer interfaces and their applications | |
Lehtonen | EEG-based brain computer interfaces | |
CN115517687A (en) | Specific neural feedback system for improving anxiety based on multi-modal fusion | |
CN101382837A (en) | Computer mouse control device of compound motion mode | |
Chu et al. | Physiological signals based quantitative evaluation method of the pain | |
Hakonen et al. | More comprehensive proprioceptive stimulation of the hand amplifies its cortical processing | |
CN106037645A (en) | Near-infrared brain imaging spectrum classifying method based on cognition task testing | |
CN107595295B (en) | A kind of lower extremity movement resistive state recognition methods based on brain hemoglobin information | |
Michel et al. | Rapid information processing and concomitant event-related brain potentials in smokers differing in CO absorption | |
CN110363242B (en) | Brain consciousness multi-classification method and system based on support vector machine | |
Virji-Babul et al. | Neural mechanisms underlying action observation in adults with down syndrome |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant |