CN104764648B - A kind of urine purifier and its purification process tested for iodide ion in urine - Google Patents
A kind of urine purifier and its purification process tested for iodide ion in urine Download PDFInfo
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- CN104764648B CN104764648B CN201410003953.3A CN201410003953A CN104764648B CN 104764648 B CN104764648 B CN 104764648B CN 201410003953 A CN201410003953 A CN 201410003953A CN 104764648 B CN104764648 B CN 104764648B
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Abstract
The invention discloses a kind of urine purifier tested for iodide ion in urine, including the identical bottle body of two structures, the bottle body is a hollow flexible plastic bottle body, and the bottle body upper end is provided with bottle cap；A hollow drip nozzle is provided on the bottle cap；The bottom surface of the bottle cap is set as funnel-form, which is drip nozzle mouth；The bottle cap inner wall is provided with spiral mouth lines, and the card film ring that a circle matches with the bottle cap inner diameter size is provided between the spiral mouth lines and the bottle cap bottom surface, is provided with filter membrane between the card film ring and the bottom surface of the bottle cap；Flocculant is respectively provided in two bottle bodies and does not adsorb the adsorbent of iodide ion.The invention also discloses a kind of methods of urine purifying.Urine purifier provided by the invention, the device is easy to use, can effectively remove in urine to the noisy visible component of electro-chemical test and reducing agent, increase the accuracy of iodide ion content measurement in urine.
Description
Technical field
The present invention relates to a kind of urine purifiers and its purification process tested for iodide ion in urine.
Background technique
Iodine is one of micro elements needed by human, and urine iodine level is to evaluate an important indicator of local IDD(Iodine deficiency disorders).
Currently, the content of iodine mainly uses wet process acid digestion or dry method alkaline ashing processing urine sample in urine, light is then catalyzed by arsenic cerium
Degree method is measured.The pretreatment of urine sample is cumbersome time-consuming in detection process, and complicated for operation, cost in Catalytic Spectrophotometric Determination
It is higher, and noxious material arsenious acid is used, it is unsuitable for clinical sample analysis.
Electrochemical analysis techniques have high sensitivity, easy to operate, at low cost and instrument compared with the analysis methods such as photometry
The portable advantage of device.N.K.Zaitsev et al. (Journal of Analytical Chemistry 2004, Vol.59,
Pp.474-480 the method using iodide ion in electrochemical method test solution) is proposed, but since method is by albumen, reducing agent
Deng be affected, using alkaline process be ashed method processing sample after obtain good result.Shunxun Yang et al. (Anal.
Chem., 1991, Vol.63, pp.2970-2973) using Oxygen bottle combustion method remove egg, the albumen in animal's liver and
Then reducing component tests iodide ion content using electrochemical method.Guy E.Abraham et al. (The Original
Internist, 2004, pp.19-32) using the iodide ion in anion exchange resin absorption urine, through high-concentration sodium nitrate
After elution, iodide ion concentration is tested using ion selective electrode.
Urine is the product of human metabolism, complicated component.The visible components such as sediment can occupy the work of electrode in urine
Property area cause signal to inhibit, and the reproducibilities ingredient such as ascorbic acid, bilirubin in urine generate electric current meeting and iodide ion
Electric current superposition, cause signal to be unable to measure.The digestion of acid system or alkaline process, Oxygen bottle combustion, exchanger resin purifying that forefathers use etc.
There is the disadvantages of cumbersome, time-consuming and laborious.
Summary of the invention
The technical problem to be solved by the present invention is to overcome the defects of the prior art, provide a kind of for iodide ion survey in urine
The urine purifier of examination, the device is easy to use, can remove in urine to the noisy visible component of electro-chemical test
And reducing agent, increase the accuracy of iodide ion content measurement in urine.
The present invention also provides a kind of urine purification process tested for iodide ion in urine.
In order to solve the above-mentioned technical problems, the present invention provides the following technical solutions:
A kind of urine purifier tested for iodide ion in urine of the present invention, including the identical bottle body of two structures,
The bottle body is a hollow flexible plastic bottle body, and the bottle body upper end is provided with bottle cap；It is hollow that one is provided on the bottle cap
Drip nozzle；The bottom surface of the bottle cap is set as funnel-form, which is drip nozzle mouth；The bottle cap inner wall
It is provided with spiral mouth lines, a circle and the bottle cap inner diameter size are provided between the spiral mouth lines and the bottle cap bottom surface
The card film ring to match, is provided with filter membrane between the card film ring and the bottom surface of the bottle cap；It is filled respectively in two bottle bodies
There is flocculant and does not adsorb the adsorbent of iodide ion.
Further, a circle indentation is provided on the outer surface of the drip nozzle.The drip nozzle is sealed at the beginning
, it needs to fracture when in use to expose its oral area, by being arranged a circle indentation on its outer surface, when use can easily be broken
It is disconnected, expose drip nozzle mouth.
Further, the bottom surface of the bottle cap is provided with diversion trench.
Further, the diversion trench is in the spoke-like of protrusion.
Further, the card film ring is rubber card film ring.
Further, the flocculant is aluminium chloride or fumed silica, and the dosage of the flocculant is every milliliter
50-300mg is added in urine.
Further, the dosage of the flocculant is the aluminium chloride that 200mg is added in every milliliter of urine.
Further, adsorbent is mainly used for removing the reducing substances such as ascorbic acid, bilirubin, the gallbladder original in urine.
Active carbon can be used in adsorbent, the mesh number of active carbon between 100-300 mesh, the more low then adsorption capacity of the mesh number of active carbon more
Weak, mesh number more high absorption capacity is stronger.The optimal mesh number of active carbon is 200 mesh, adsorption area 900-1500m2/ g, every milliliter
The processed active carbon of 0.15g can be added in urine.After active carbon is impregnated 3 ~ 6 hours in the hydrochloric acid of 0.1 ~ 0.3mol/L,
Being rinsed using deionized water to pH is 5-6, is placed under 115 °C and toasts 2 hours.In the adsorbable urine of active carbon through this processing
The reducing substances such as ascorbic acid, bilirubin, without adsorbing iodide ion.
Further, the filter membrane is water system porous membrane of the aperture between 0.45-0.8 μm, the material of the filter membrane
For filter paper, polypropylene, polytetrafluoroethylene (PTFE), cellulose acetate.
A kind of urine purification process tested for iodide ion in urine, comprising the following steps:
(1) compound concentration is the liquor alumini chloridi of 20g/L, and 20 μ L liquor alumini chloridis is taken to be added in a bottle body, then will
The bottle body is placed in baking oven to be toasted 2 hours under 60 ~ 80 °C, screws bottle cap after baking is cooling, and marking the bottle is A bottles, spare；
(2) it after impregnating active carbon 3 ~ 6 hours in the hydrochloric acid of 0.1 ~ 0.3mol/L, is rinsed using deionized water to pH and is
5-6 is placed under 115 °C and toasts 2 hours, 0.3g is taken to be added in a bottle body, spare labeled as B bottles；
(3) A bottles are opened, 2mL freshly voided urine is taken to be placed in A bottles, is rocked uniformly after covering tightly bottle cap；
(4) B bottles are opened, A bottles of solution is extruded into completely in B bottles after breaking disconnected A bottles of drip nozzle, is rocked after covering tightly bottle cap
It is even.
The beneficial effects obtained by the present invention are as follows being:
The apparatus structure that invention provides is simple and convenient to operate, economical and practical.It is tangible in urine in electro-chemical test
Ingredient often occupies the active area of electrode surface, reduces the activity of electrode；Ascorbic acid, bilirubin in urine etc. are also
The electric current that former agent generates can be superimposed upon on the peak current of iodide ion, made background current much higher than signal code, can not accurately be measured.
Formation in urine (such as cell, tubular, urinary crystal) can be effectively removed using the present apparatus, can also be effectively removed in urine
Reproducibility ingredient (such as ascorbic acid, bilirubin), and to iodide ion without absorption.
Detailed description of the invention
Attached drawing is used to provide further understanding of the present invention, and constitutes part of specification, with reality of the invention
It applies example to be used to explain the present invention together, not be construed as limiting the invention.In the accompanying drawings:
Fig. 1 is overall structure diagram of the invention；
Fig. 2 is the structural schematic diagram of bottle body；
Fig. 3 is the structural schematic diagram of bottle cap；
Fig. 4 is the overlooking structure diagram of bottle cap；
Fig. 5 is the overlooking structure diagram of card film ring
Fig. 6 is to purify and do not purify iodide ion in urine to test signal comparative effectiveness figure；
Fig. 7 is the anti-interference ability effect picture of purification devices Ascorbic Acid.
Specific embodiment
Hereinafter, preferred embodiments of the present invention will be described with reference to the accompanying drawings, it should be understood that preferred reality described herein
Apply example only for the purpose of illustrating and explaining the present invention and is not intended to limit the present invention.
Embodiment 1
As shown in Figures 1 to 5, a kind of urine purifier tested for iodide ion in urine of the present invention, including two
The identical bottle body 3 of structure, the bottle body 3 are a hollow flexible plastic bottle body, and 3 upper end of bottle body is provided with bottle cap 1；The bottle
A hollow drip nozzle 7 is provided on lid 1；The bottom surface of the bottle cap 1 is set as funnel-form, funnelform bottom center's recess
For drip nozzle mouth (not shown)；The inner wall of the bottle cap 1 is provided with spiral mouth lines, the spiral mouth lines and the bottle cap
The card film ring 2 that a circle matches with the bottle cap inner diameter size, the card film ring 2 and the bottle cap 1 are provided between 1 bottom surface
Bottom surface between be provided with filter membrane 5；Flocculant is respectively provided in two bottle bodies 3 and does not adsorb the adsorbent of iodide ion.
A circle indentation 6 is provided on the outer surface of the drip nozzle 7.The drip nozzle 7 is sealed at the beginning, is made
Used time needs to fracture to expose its oral area, and by being arranged a circle indentation 6 on its outer surface, when use can easily break disconnected, dew
Drip nozzle mouth out.
The bottom surface of the bottle cap 1 is provided with diversion trench 4.The diversion trench 4 is spoke-like in protrusion.The card film ring 2 is
Rubber card film ring.
The dosage of the flocculant is the aluminium chloride that 200mg is added in every milliliter of urine.
Adsorbent is mainly used for removing the reducing substances such as ascorbic acid, bilirubin, the gallbladder original in urine.Adsorbent uses
Active carbon, the mesh number of active carbon are 200 mesh, adsorption area 900-1500m2It is processed that 0.15g is added in every milliliter of urine by/g
Active carbon.After active carbon is impregnated 4 hours in the hydrochloric acid of 0.1mol/L, being rinsed using deionized water to pH is 6, is placed in
It is toasted 2 hours under 115 °C.The reducing substances such as ascorbic acid, bilirubin in the adsorbable urine of active carbon through this processing, and
Do not adsorb iodide ion.
The filter membrane 5 is the polypropylene screen in 0.8 μm of aperture.
A kind of urine purification process tested for iodide ion in urine, comprising the following steps:
(1) compound concentration is the liquor alumini chloridi of 20g/L, and 20 μ L liquor alumini chloridis is taken to be added in a bottle body, then will
The bottle body is placed in baking oven to be toasted 2 hours under 75 °C, screws bottle cap after baking is cooling, and marking the bottle is A bottles, spare；
(2) after impregnating active carbon 4 hours in the hydrochloric acid of 0.1mol/L, being rinsed using deionized water to pH is 5-6, and
It is placed under 115 °C and toasts 2 hours, 0.3g is taken to be added in a bottle body, it is spare labeled as B bottles；
(3) A bottles are opened, 2mL freshly voided urine is taken to be placed in A bottles, is rocked uniformly after covering tightly bottle cap；
(4) B bottles are opened, A bottles of solution is extruded into completely in B bottles after breaking disconnected A bottles of drip nozzle, is rocked after covering tightly bottle cap
It is even；
Embodiment 2
The present embodiment does not change the structure of bottle body, is only improved on the basis of embodiment 1: the present embodiment is by two
Bottle synthesizes a bottle, only changes reagent and manufacturing method in bottle body.
A kind of urine purification process tested for iodide ion in urine, comprising the following steps:
(1) after impregnating 100g active carbon 4 hours in the hydrochloric acid of 0.1M, being rinsed using deionized water to pH is 5-6.It will
The active carbon that soaking flushing is crossed is placed under 115 °C and toasts 2 hours；
(2) compound concentration is the fumed silica solution of 20g/L, takes 20 μ L silicon dioxde solutions to be added in bottle body, sets
It is toasted under 75 °C in baking oven 2 hours, 0.3g step (1) processed active carbon is then added in bottle body, screws bottle cap
It is spare.
(3) bottle body is opened, 2mL freshly voided urine is taken to be placed in bottle body, is rocked uniformly after covering tightly bottle cap.
Fig. 6 be purifying and do not purify the test of iodide ion in urine signal comparative effectiveness figure (iodine in urine containing 138 μ g/L from
Son)；Fig. 7 is that the anti-interference ability effect picture of purification devices Ascorbic Acid (contains the iodide ion of 138 μ g/L, 3500mg/ in urine
The ascorbic acid of L).The device that invention provides it can be seen from Fig. 6 and Fig. 7, it is good to the purification effect of urine, it is effective to remove
In urine in determination of the content of iodine other impurities interference, increase the accuracy of result.
Finally, it should be noted that the foregoing is only a preferred embodiment of the present invention, it is not intended to restrict the invention,
Although the present invention is described in detail referring to the foregoing embodiments, for those skilled in the art, still may be used
To modify the technical solutions described in the foregoing embodiments or equivalent replacement of some of the technical features.
All within the spirits and principles of the present invention, any modification, equivalent replacement, improvement and so on should be included in of the invention
Within protection scope.
Claims (1)
1. a kind of urine purification process using urine purifier, which includes the identical bottle of two structures
Body, the bottle body are a hollow flexible plastic bottle body, and the bottle body upper end is provided with bottle cap；It is hollow that one is provided on the bottle cap
Drip nozzle；The bottom surface of the bottle cap is set as funnel-form, which is drip nozzle mouth；In the bottle cap
Wall is provided with spiral mouth lines, and a circle is provided between the spiral mouth lines and the bottle cap bottom surface and the bottle cap internal diameter is big
The small card film ring to match, is provided with filter membrane between the card film ring and the bottom surface of the bottle cap；In two bottle bodies respectively
The adsorbent of iodide ion is not adsorbed equipped with flocculant and；The flocculant is aluminium chloride, the adsorbent for not adsorbing iodide ion
For active carbon；
Characterized by comprising the following steps:
(1) compound concentration is the liquor alumini chloridi of 20g/L, takes 20 μ L liquor alumini chloridis to be added in a bottle body, then by the bottle
Body is placed in baking oven to be toasted 2 hours under 60 ~ 80 °C, screws bottle cap after baking is cooling, and marking the bottle is A bottles, spare；
(2) after impregnating active carbon 3 ~ 6 hours in the hydrochloric acid of 0.1 ~ 0.3mol/L, being rinsed using deionized water to pH is 5-6,
It is placed under 115 °C and toasts 2 hours, 0.3g is taken to be added in a bottle body, it is spare labeled as B bottles；
(3) A bottles are opened, 2mL freshly voided urine is taken to be placed in A bottles, is rocked uniformly after covering tightly bottle cap；
(4) B bottles are opened, A bottles of solution is extruded into completely in B bottles after breaking disconnected A bottles of drip nozzle, is rocked uniformly after covering tightly bottle cap；
A circle indentation is provided on the outer surface of the drip nozzle；The bottom surface of the bottle cap is provided with diversion trench；The diversion trench is in
Raised is spoke-like；The card film ring is rubber card film ring；The dosage of the flocculant is to be added 200mg's in every milliliter of urine
Aluminium chloride；The filter membrane is water system porous membrane of the aperture between 0.45-0.8 μm, and the material of the filter membrane is filter paper, poly- third
Alkene, polytetrafluoroethylene (PTFE), cellulose acetate.
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| CN201410003953.3A CN104764648B (en) | 2014-01-04 | 2014-01-04 | A kind of urine purifier and its purification process tested for iodide ion in urine |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410003953.3A CN104764648B (en) | 2014-01-04 | 2014-01-04 | A kind of urine purifier and its purification process tested for iodide ion in urine |
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| CN104764648A CN104764648A (en) | 2015-07-08 |
| CN104764648B true CN104764648B (en) | 2019-04-23 |
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| CN106311155B (en) * | 2016-08-18 | 2019-02-01 | 中南林业科技大学 | A kind of modified cellulose aeroge and preparation method thereof purifying urine |
| CN108333015B (en) * | 2017-01-18 | 2022-06-03 | 西安市宇驰检测技术有限公司 | Structure and method for determining hexavalent chromium in water |
| KR101876700B1 (en) * | 2018-01-02 | 2018-07-18 | 주식회사 세종바이오메드 | Cell collector |
| CN114152737A (en) * | 2021-12-08 | 2022-03-08 | 惠州市阳光生物科技有限公司 | Urine galactose detect reagent box |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6150691A (en) * | 1984-08-20 | 1986-03-12 | Kurita Water Ind Ltd | Treatment of excretion sewage |
| CN2725885Y (en) * | 2004-08-20 | 2005-09-14 | 北京金域高科诊断技术有限公司 | Injection type urine purifier |
| CN1811394A (en) * | 2006-03-07 | 2006-08-02 | 北京中生金域诊断技术有限公司 | Urine iodine test reagent kit |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002053256A1 (en) * | 2001-01-05 | 2002-07-11 | Pro-Chem, Inc. | Devices and methods for purification |
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2014
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6150691A (en) * | 1984-08-20 | 1986-03-12 | Kurita Water Ind Ltd | Treatment of excretion sewage |
| CN2725885Y (en) * | 2004-08-20 | 2005-09-14 | 北京金域高科诊断技术有限公司 | Injection type urine purifier |
| CN1811394A (en) * | 2006-03-07 | 2006-08-02 | 北京中生金域诊断技术有限公司 | Urine iodine test reagent kit |
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Address after: 214000 No. 1699 Huishan Avenue, Huishan District, Wuxi City, Jiangsu Province Patentee after: Wuxi Shenrui Bio-Pharmaceuticals Co., Ltd. Address before: 214000, Wuxi, Jiangsu province Binhu District Ma Shan Mei Liang West Road, No. 88 Patentee before: Wuxi Shenrui Bio-Pharmaceuticals Co., Ltd. |
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Denomination of invention: The invention relates to a urine purification device for testing iodine ion in urine and a purification method thereof Effective date of registration: 20210425 Granted publication date: 20190423 Pledgee: Bank of Jiangsu Limited by Share Ltd. Wuxi science and Technology Branch Pledgor: WUXI SHENRUI BIO-PHARMACEUTICALS Co.,Ltd. Registration number: Y2021320010150 |
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