CN104749382B - Without the real-time glomerular filtration rate(GFR fast detector of wound - Google Patents
Without the real-time glomerular filtration rate(GFR fast detector of wound Download PDFInfo
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- CN104749382B CN104749382B CN201510186559.2A CN201510186559A CN104749382B CN 104749382 B CN104749382 B CN 104749382B CN 201510186559 A CN201510186559 A CN 201510186559A CN 104749382 B CN104749382 B CN 104749382B
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- gatherer
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/34—Genitourinary disorders
- G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
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Abstract
Without the real-time glomerular filtration rate(GFR fast detector of wound, it relates to technical field of medical equipment, gatherer is provided with collection handle, collect handle to be connected with receiver shell internal circuit board by data line, receiver shell is separately installed with receiver display screen, receiver operating key, the back side of receiver shell is provided with gatherer groove, and the both sides of gatherer groove are all provided with electro-heat equipment, and power connection is arranged on the top of receiver shell; It is convenient to without wound, detects fast, and detection time is short, convenient and swift, and be easy to promote, simple to operate, work efficiency is high.
Description
Technical field
The present invention relates to technical field of medical equipment, be specifically related to a kind of without the real-time glomerular filtration rate(GFR fast detector of wound.
Background technology
Uremic patient is often with anaemia in various degree, and more to the later stage, anaemia is more serious.Often need the Real-Time Monitoring this type of patient being carried out to renal function clinically, this blood drawing (having wound) just must carried out repeatedly checks patients serum's creatinine level, has not only increased the weight of patient economy burden, anaemia more can be caused to increase the weight of.And detection blood creatinine concentration needs hospital or other medical institutions, just can go out result, cause the inconvenience of traffic to the original state of an illness with regard to heavier patient after waiting for a few hours.In addition, carry out evaluate patient renal function by serum creatinine level inherently not bery accurate, because only have when 1/3 ~ 1/2 of glomerular filtration rate(GFR (GFR) decline normal value, be just likely detected.Moreover serum creatinine level is by the impact of the factors such as Gender, diet, Lean mass, and fluctuation is comparatively large, carrys out evaluate patient renal function by serum creatinine concentration, obviously there is larger defect.And, after drawing patient's serum creatinine concentration, also need to carry out manual or special computer software formulae discovery, just can draw corresponding renal function (GFR) level.
Except detecting serum creatinine concentration, also has the method by detecting inulin clearance and radioactive isotope Tc 99m Tc detection glomerular filtration rate(GFR at present.But latter two method all will arrive medical institutions and carry out having wound to detect, and not only needs reservation, detect length consuming time (3-4 hour), and costly (400-600 unit), very inconvenient.
Recently, bladder chalone C has become the good index of evaluate patient renal function.It is produced by karyocyte, constant rate, filtered completely by glomerulus, renal tubule absorbs, but do not enter blood, and not by the impact of age, sex, albumen absorption, Lean mass, inflammation, medicine and race etc., inorganization specificity, thus be progressively used to replace serum creatinine, become the New Set of evaluate patient renal function.But it equally exists with serum creatinine need arrive hospital or medical institutions' blood drawing (having wound), many deficiencies such as consuming time.
Saliva is the mirror of human body, and abundant human body information is contained in the inside, and as bladder chalone C and creatinine etc., thus sialosemeiology has very wide application prospect and development prospect.Show according to the study, the bladder chalone C level in saliva and the bladder chalone C level in blood have good correlativity, and it is more stable than the creatinine in saliva and blood.In addition, saliva amount is abundant, can facilitate, obtain at any time, detect bladder chalone C concentration in it can make up the deficiency of blood drawing with saliva.
Summary of the invention
The object of this invention is to provide a kind of without the real-time glomerular filtration rate(GFR fast detector of wound, it is convenient to without wound, detects fast, and detection time is short, convenient and swift, and be easy to promote, simple to operate, work efficiency is high.
In order to solve the problem existing for background technology, the present invention adopts following technical scheme: it comprises gatherer, collect handle, data line, receiver display screen, receiver operating key, gatherer groove, power connection, receiver shell, gatherer is provided with collection handle, collect handle to be connected with receiver shell internal circuit board by data line, receiver shell is separately installed with receiver display screen, receiver operating key, the back side of receiver shell is provided with gatherer groove, the both sides of gatherer groove are all provided with electro-heat equipment, power connection is arranged on the top of receiver shell.
The built-in certain negative pressure of described gatherer and phosphate buffer, containing in the oral cavity, can absorb quantitative saliva fast, have the effect of unidirectional valve, saliva only import but no export; Material transparent, does not stop light.
Described collection handle is hollow handle, includes the anti-bladder chalone C polyclonal antibody of quantitative collaurum bag quilt, can be automatically injected in gatherer.
Described data line is responsible for connecting receiver and collecting handle, and transmission information and instruction arrive data processor, can be recycled.
Described receiver display screen by with the coordinating of operating key, by the age of input patient, sex, thus the renal function (glomerular filtration rate(GFR) of patient can be demonstrated.
Described receiver operating key realizes man-machine conversation, and machine can carry out self-inspection, sense data.
There is electro-heat equipment on the both sides of described accommodation gatherer groove, and maintain the constant temperature of gatherer, the emitter having the light of 546nm of groove, offside has the inductor accepting light.
The present invention has following beneficial effect: be convenient to without wound, detect fast, detection time is short, convenient and swift, and be easy to promote, simple to operate, work efficiency is high.
accompanying drawing illustrates:
Fig. 1 is structural representation of the present invention;
Fig. 2 is the rear view of receiver shell in the present invention.
Reference numeral: 1-gatherer; 2-collects handle; 3-data line; 4-receiver display screen; 5-receiver operating key; 6-gatherer groove; 7-power connection; 8-receiver shell.
embodiment:
Below in conjunction with accompanying drawing, the present invention is described in detail.
In order to make object of the present invention, technical scheme and advantage clearly understand, below in conjunction with the drawings and the specific embodiments, the present invention is further elaborated.Should be appreciated that embodiment described herein only in order to explain the present invention, be not intended to limit the present invention.
Referring to Fig. 1-Fig. 2, this embodiment adopts following technical scheme: it comprises gatherer 1, collect handle 2, data line 3, receiver display screen 4, receiver operating key 5, gatherer groove 6, power connection 7, receiver shell 8, gatherer 1 is provided with and collects handle 2, collect handle 2 to be connected with receiver shell 8 internal circuit board by data line 3, receiver shell 8 is separately installed with receiver display screen 4, receiver operating key 5, the back side of receiver shell 8 is provided with gatherer groove 6, the both sides of gatherer groove 6 are all provided with electro-heat equipment, power connection 7 is arranged on the top of receiver shell 8.
The built-in certain negative pressure of described gatherer 1 and phosphate buffer, containing in the oral cavity, can absorb quantitative saliva fast, have the effect of unidirectional valve, saliva only import but no export; Material transparent, does not stop light.
Described collection handle 2 is hollow handle, includes the anti-bladder chalone C polyclonal antibody of quantitative collaurum bag quilt, can be automatically injected in gatherer.
Described data line 3 is responsible for connecting receiver and collecting handle, and transmission information and instruction arrive data processor, can be recycled.
Described receiver display screen 4 by with the coordinating of operating key, by the age of input patient, sex, thus the renal function (glomerular filtration rate(GFR) of patient can be demonstrated.
Described receiver operating key 5 realizes man-machine conversation, and machine can carry out self-inspection, sense data.
There is electro-heat equipment on the both sides of described accommodation gatherer groove 6, and maintain the constant temperature of gatherer, the emitter having the light of 546nm of groove, offside has the inductor accepting light.
The principle of work of this embodiment is: be contained in by gatherer in oral cavity, and the saliva that quick collection is quantitative also hatches 5 minutes with phosphate buffer.Take out gatherer afterwards, put into the groove of receiver, program automatically sets and is injected in the volume of gatherer by the anti-bladder chalone C polyclonal antibody of the collaurum bag quilt in gatherer handle, and after detecting 20 seconds automatically, reads absorbance A
1, after 280 seconds, measure absorbance A
2, and calculate the concentration of bladder chalone C.Inputted age and the sex of patient by operator, carry software according to system, be automatically updated to (formula sees the following form) in formula, just can calculate the renal function (glomerular filtration rate(GFR) of patient, thus reach in real time, without wound and advantage fast.
| Sex | Serum bladder chalone C (mg/L) | GFR formula (>=18y) |
| Man or female | ≤0.8 | GFR=133×(SCysC/0.8) -0.499×0.996 Age[×0.932 if female] |
| Man or female | ＞0.8 | GFR=133×(SCysC/0.8) -1.328×0.996 Age[×0.932 if female] |
The above, only in order to technical scheme of the present invention to be described and unrestricted, other amendment that those of ordinary skill in the art make technical scheme of the present invention or equivalently to replace, only otherwise depart from the spirit and scope of technical solution of the present invention, all should be encompassed in the middle of right of the present invention.
Claims (2)
1. without the real-time glomerular filtration rate(GFR fast detector of wound, it is characterized in that it comprises gatherer (1), collect handle (2), data line (3), receiver display screen (4), receiver operating key (5), gatherer groove (6), power connection (7), receiver shell (8), gatherer (1) is provided with and collects handle (2), collect handle (2) to be connected with receiver shell (8) internal circuit board by data line (3), receiver shell (8) is separately installed with receiver display screen (4), receiver operating key (5), the back side of receiver shell (8) is provided with gatherer groove (6), the both sides of gatherer groove (6) are all provided with electro-heat equipment, power connection (7) is arranged on the top of receiver shell (8), the built-in certain negative pressure of described gatherer and phosphate buffer, described collection handle includes the anti-bladder chalone C polyclonal antibody of quantitative collaurum bag quilt.
2. according to claim 1 without the real-time glomerular filtration rate(GFR fast detector of wound, it is characterized in that described collection handle (2) is hollow handle.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510186559.2A CN104749382B (en) | 2015-04-20 | 2015-04-20 | Without the real-time glomerular filtration rate(GFR fast detector of wound |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510186559.2A CN104749382B (en) | 2015-04-20 | 2015-04-20 | Without the real-time glomerular filtration rate(GFR fast detector of wound |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104749382A CN104749382A (en) | 2015-07-01 |
| CN104749382B true CN104749382B (en) | 2016-04-27 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201510186559.2A Expired - Fee Related CN104749382B (en) | 2015-04-20 | 2015-04-20 | Without the real-time glomerular filtration rate(GFR fast detector of wound |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105277723B (en) * | 2015-11-26 | 2017-03-08 | 北京大学第一医院 | A kind of detecting system of glomerular filtration rate |
| CN106053379A (en) * | 2016-05-16 | 2016-10-26 | 南昌大学第二附属医院 | IgA nephrosis (IgAN) treatment scheme comprehensive evaluating device |
| CN111746288B (en) * | 2020-06-12 | 2023-03-14 | 南昌大学 | Design method of active power-off protection system based on environment perception collision |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5056521A (en) * | 1989-06-29 | 1991-10-15 | Health Craft International, Inc. | Method for monitoring glucose level |
| US20030166259A1 (en) * | 2001-12-04 | 2003-09-04 | Dave Smith | Method for accurately mixing sample and buffer solutions |
| EP1397997A1 (en) * | 2002-09-04 | 2004-03-17 | Friedrich-Alexander-Universität Erlangen-Nürnberg | Detection device |
| CN2704045Y (en) * | 2004-07-12 | 2005-06-08 | 艾康生物技术(杭州)有限公司 | Portable sample detecting device |
| KR100883555B1 (en) * | 2005-11-15 | 2009-02-17 | 한메딕스 주식회사 | Novel quantitative and qualitative analysis apparatus for measuring the body fluid |
| US7741103B2 (en) * | 2006-03-31 | 2010-06-22 | Guirguis Raouf A | Integrated screening and confirmation device |
| CN101496729B (en) * | 2009-03-17 | 2010-09-15 | 北京大学口腔医学院 | Device for collecting parotid sputum |
| CN101699287B (en) * | 2009-09-08 | 2013-04-24 | 北京利德曼生化股份有限公司 | Homogeneous phase sol particle type cystatin C measuring kit and preparation method thereof |
| CN102462512A (en) * | 2010-11-01 | 2012-05-23 | 美艾利尔圣地亚哥有限公司 | Collection device with liquid adequate volume sensor |
| CN202083691U (en) * | 2011-06-02 | 2011-12-21 | 杨吉飞 | Saliva-based multifunctional detecting instrument |
| CN203122469U (en) * | 2013-02-25 | 2013-08-14 | 淄博职业学院 | Negative pressure type animal saliva collector |
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| CN104749382A (en) | 2015-07-01 |
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