CN104743879A - Anti-corrosive bioglass and preparation method thereof - Google Patents
Anti-corrosive bioglass and preparation method thereof Download PDFInfo
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- CN104743879A CN104743879A CN201510145158.2A CN201510145158A CN104743879A CN 104743879 A CN104743879 A CN 104743879A CN 201510145158 A CN201510145158 A CN 201510145158A CN 104743879 A CN104743879 A CN 104743879A
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Abstract
The invention discloses an anti-corrosive bioglass and a preparation method thereof. The ceramic comprises the following raw materials in parts by weight: 80-90 parts of sodium oxide, 10-20 parts of calcium oxide, 4-6 parts of silicon dioxide, 7-12 parts of phosphorus pentoxide, 9-10 parts of potassium oxide, 10-20 parts of a surfactant, 10-20 parts of calcium fluoride and 20-30 parts of an initiator. The preparation method comprises the following steps: adding the sodium oxide, the calcium oxide, the silicon dioxide, the phosphorus pentoxide, the potassium oxide, the surfactant, the calcium fluoride and the initiator in a platinum crucible, insulating for 1-2h at 1200-1500 DEG C, quenching and then crushing, and sieving; carrying out compression moulding on glass powder. According to the anti-corrosive bioglass and the preparation method thereof disclosed by the invention, a certain amount of fluorine ions and potassium ions is added in the components, so that the bioactivity of the bioglass can be improved, the degradability thereof can be weakened, and the corrosion resistance can be improved.
Description
Technical field
The present invention relates to biological technical field, particularly relate to a kind of corrosion-resistant bio-vitric and preparation method thereof.
Background technology
Fluorine is one of essential trace element of human life activity, and the fluorine content 2.6g in normal human, is only second to silicon and iron.The fluorine of 90% is distributed in the sclerous tissues such as human skeleton and tooth, is mainly deposited in loose sclerotin with the form of inorganic fluorine.Fluorine has vital role to growing and maintaining bone physiological structure function of whole body bone.After hydroxyl in fluorion substituted hydroxy phosphatic rock, due to the difference of ionic radius between fluorine and hydroxyl and character, thus the lattice of hydroxyapatite is distorted, change its crystallinity and structural stability.In addition, when applying as oral cavity material, the dense surface structure that F-HA (phosphatic rock of fluorion substituted hydroxy) has can reduce surface free energy, reduces the adhesion of bacterium, utilizes F
-bacteriostatic action prevent and treat carious tooth.
The biomaterial corrosion resistance nature that prior art fluorine replaces is not strong, is easily corroded.
Summary of the invention
The present invention is directed to the deficiencies in the prior art, provide a kind of corrosion-resistant bio-vitric and preparation method thereof, degradation property is low, and erosion resistance is strong.
The present invention is by the following technical solutions:
Corrosion-resistant bio-vitric, comprises the raw material of following parts by weight: sodium oxide 80 ~ 90 parts, 10 ~ 20 parts, calcium oxide, silicon-dioxide 4 ~ 6 parts, Vanadium Pentoxide in FLAKES 7 ~ 12 parts, potassium oxide 9 ~ 10 parts, 10 ~ 20 parts, tensio-active agent, 10 ~ 20 parts, Calcium Fluoride (Fluorspan), initiator 20 ~ 30 parts.
As preferably, tensio-active agent is one or more in glyceryl monostearate, sorbitan sesquioleate, propylene glycol fatty acid ester or dioctyl sodium sulfosuccinate.
As preferably, the particle diameter of Calcium Fluoride (Fluorspan) is 100-300nm.
As preferably, initiator is one or more in Diisopropyl azodicarboxylate, ammonium persulphate or benzoyl peroxide.
The preparation method of above-mentioned corrosion-resistant bio-vitric, comprise the following steps: sodium oxide, calcium oxide, silicon-dioxide, Vanadium Pentoxide in FLAKES, potassium oxide, tensio-active agent, Calcium Fluoride (Fluorspan), initiator are added in platinum crucible, in 1200 ~ 1500 DEG C of insulation 1 ~ 2h, pulverize after quenching, screening; By glass powder compression moulding.
As preferably, sieve size is 300 ~ 800 orders.
The present invention adds a certain amount of fluorion and potassium ion in moiety, can improve the biological activity of bio-vitric, weakens its degradation property, improves corrosion resistance nature.
Embodiment
Below in conjunction with specific embodiment, the present invention is further described in detail.
embodiment 1
Corrosion-resistant bio-vitric, comprises the raw material of following parts by weight: sodium oxide 80 parts, 20 parts, calcium oxide, silicon-dioxide 6 parts, Vanadium Pentoxide in FLAKES 12 parts, potassium oxide 10 parts, 20 parts, tensio-active agent, 20 parts, Calcium Fluoride (Fluorspan), initiator 30 parts.
Tensio-active agent is glyceryl monostearate, the sorbitan sesquioleate of mass ratio 1:2.
The particle diameter of Calcium Fluoride (Fluorspan) is 100nm.
Diisopropyl azodicarboxylate, ammonium persulphate that initiator is mass ratio 1:2.
The preparation method of above-mentioned corrosion-resistant bio-vitric, comprise the following steps: sodium oxide, calcium oxide, silicon-dioxide, Vanadium Pentoxide in FLAKES, potassium oxide, tensio-active agent, Calcium Fluoride (Fluorspan), initiator are added in platinum crucible, in 1200 DEG C of insulation 1h, pulverize after quenching, screening; By glass powder compression moulding.
Sieve size is 300 orders.
embodiment 2
Corrosion-resistant bio-vitric, comprises the raw material of following parts by weight: sodium oxide 90 parts, 20 parts, calcium oxide, silicon-dioxide 6 parts, Vanadium Pentoxide in FLAKES 12 parts, potassium oxide 10 parts, 20 parts, tensio-active agent, 20 parts, Calcium Fluoride (Fluorspan), initiator 30 parts.
Tensio-active agent is glyceryl monostearate, sorbitan sesquioleate, propylene glycol fatty acid ester, the dioctyl sodium sulfosuccinate of mass ratio 1:2:1:7.
The particle diameter of Calcium Fluoride (Fluorspan) is 300nm.
Initiator is Diisopropyl azodicarboxylate, the benzoyl peroxide of mass ratio 1:4.
The preparation method of above-mentioned corrosion-resistant bio-vitric, comprise the following steps: sodium oxide, calcium oxide, silicon-dioxide, Vanadium Pentoxide in FLAKES, potassium oxide, tensio-active agent, Calcium Fluoride (Fluorspan), initiator are added in platinum crucible, in 1500 DEG C of insulation 2h, pulverize after quenching, screening; By glass powder compression moulding.
Sieve size is 800 orders.
embodiment 3
Corrosion-resistant bio-vitric, comprises the raw material of following parts by weight: sodium oxide 85 parts, 15 parts, calcium oxide, silicon-dioxide 4.6 parts, Vanadium Pentoxide in FLAKES 10 parts, potassium oxide 9.5 parts, 15 parts, tensio-active agent, 15 parts, Calcium Fluoride (Fluorspan), initiator 25 parts.
Tensio-active agent is glyceryl monostearate, propylene glycol fatty acid ester, the dioctyl sodium sulfosuccinate of mass ratio 3:1:1.
The particle diameter of Calcium Fluoride (Fluorspan) is 200nm.
Initiator is Diisopropyl azodicarboxylate, ammonium persulphate, the benzoyl peroxide of mass ratio 7:1:1.
The preparation method of above-mentioned corrosion-resistant bio-vitric, comprise the following steps: sodium oxide, calcium oxide, silicon-dioxide, Vanadium Pentoxide in FLAKES, potassium oxide, tensio-active agent, Calcium Fluoride (Fluorspan), initiator are added in platinum crucible, in 1300 DEG C of insulation 1.5h, pulverize after quenching, screening; By glass powder compression moulding.
Sieve size is 500 orders.
embodiment 4
Corrosion-resistant bio-vitric, comprises the raw material of following parts by weight: sodium oxide 88 parts, 18 parts, calcium oxide, silicon-dioxide 4.6 parts, Vanadium Pentoxide in FLAKES 11 parts, potassium oxide 10 parts, 11 parts, tensio-active agent, 17 parts, Calcium Fluoride (Fluorspan), initiator 26 parts.
Tensio-active agent is glyceryl monostearate, sorbitan sesquioleate, propylene glycol fatty acid ester, the dioctyl sodium sulfosuccinate of mass ratio 1:4:1:6.
The particle diameter of Calcium Fluoride (Fluorspan) is 220nm.
Initiator is Diisopropyl azodicarboxylate, ammonium persulphate, the benzoyl peroxide of mass ratio 1:3:1.
The preparation method of above-mentioned corrosion-resistant bio-vitric, comprise the following steps: sodium oxide, calcium oxide, silicon-dioxide, Vanadium Pentoxide in FLAKES, potassium oxide, tensio-active agent, Calcium Fluoride (Fluorspan), initiator are added in platinum crucible, in 1300 DEG C of insulation 1.2h, pulverize after quenching, screening; By glass powder compression moulding.
Sieve size is 600 orders.
comparative example 1
Identical with embodiment 1, difference is: do not add potassium oxide and Calcium Fluoride (Fluorspan) in moiety.
performance test: the corrosion-resistant bio-vitric of embodiment 1 ~ 4 and comparative example 1 to be placed on respectively in tri methylol amino methane-hydrochloric acid buffer solution 28 days, to measure the weight that they lose, compare its external degradation performance.
| Comparative example 1 | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | |
| Weight (g) before measuring | 500 | 480 | 494 | 500 | 496 |
| Weight (g) after measuring | 460 | 478 | 493 | 499 | 495 |
| Lose weight (g) | 40 | 2 | 1 | 1 | 1 |
| Rate of weight loss % | 8 | 0.4 | 0.2 | 0.2 | 0.2 |
Invention introduces fluorion and potassium ion, can significantly improve the biological activity of bio-vitric, reduce its degradation property, place 28 days in tri methylol amino methane-hydrochloric acid buffer solution, changes in weight is minimum, and erosion resistance is strong.
Be only wherein several specific embodiments of the application above, but the application is not limited thereto, the changes that any person skilled in the art can think of, all should drops in the protection domain of the application.
Claims (6)
1. corrosion-resistant bio-vitric, it is characterized in that, comprise the raw material of following parts by weight: sodium oxide 80 ~ 90 parts, 10 ~ 20 parts, calcium oxide, silicon-dioxide 4 ~ 6 parts, Vanadium Pentoxide in FLAKES 7 ~ 12 parts, potassium oxide 9 ~ 10 parts, 10 ~ 20 parts, tensio-active agent, 10 ~ 20 parts, Calcium Fluoride (Fluorspan), initiator 20 ~ 30 parts.
2. corrosion-resistant bio-vitric according to claim 1, is characterized in that, tensio-active agent is one or more in glyceryl monostearate, sorbitan sesquioleate, propylene glycol fatty acid ester or dioctyl sodium sulfosuccinate.
3. corrosion-resistant bio-vitric according to claim 1, is characterized in that, the particle diameter of Calcium Fluoride (Fluorspan) is 100-300nm.
4. corrosion-resistant bio-vitric according to claim 1, is characterized in that, initiator is one or more in Diisopropyl azodicarboxylate, ammonium persulphate or benzoyl peroxide.
5. based on the preparation method of corrosion-resistant bio-vitric according to claim 1, it is characterized in that, comprise the following steps: sodium oxide, calcium oxide, silicon-dioxide, Vanadium Pentoxide in FLAKES, potassium oxide, tensio-active agent, Calcium Fluoride (Fluorspan), initiator are added in platinum crucible, in 1200 ~ 1500 DEG C of insulation 1 ~ 2h, pulverize after quenching, screening; By glass powder compression moulding.
6. the preparation method of corrosion-resistant bio-vitric according to claim 5, is characterized in that, sieve size is 300 ~ 800 orders.
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| CN201510145158.2A CN104743879A (en) | 2015-03-31 | 2015-03-31 | Anti-corrosive bioglass and preparation method thereof |
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| CN201510145158.2A CN104743879A (en) | 2015-03-31 | 2015-03-31 | Anti-corrosive bioglass and preparation method thereof |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1213355A (en) * | 1996-01-29 | 1999-04-07 | 巴尔的摩的马里兰大学 | Bioactive glass compositions and methods of treatment using bioactive glass |
| US6756060B1 (en) * | 1996-09-19 | 2004-06-29 | Usbiomaterials Corp. | Anti-inflammatory and antimicrobial uses for bioactive glass compositions |
| CN101407373A (en) * | 2008-11-18 | 2009-04-15 | 湖北顶盛科技发展有限公司 | Strontium-reinforced bioactivity glass, production method there and use in tooth-cleaning products |
-
2015
- 2015-03-31 CN CN201510145158.2A patent/CN104743879A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1213355A (en) * | 1996-01-29 | 1999-04-07 | 巴尔的摩的马里兰大学 | Bioactive glass compositions and methods of treatment using bioactive glass |
| US6756060B1 (en) * | 1996-09-19 | 2004-06-29 | Usbiomaterials Corp. | Anti-inflammatory and antimicrobial uses for bioactive glass compositions |
| CN101407373A (en) * | 2008-11-18 | 2009-04-15 | 湖北顶盛科技发展有限公司 | Strontium-reinforced bioactivity glass, production method there and use in tooth-cleaning products |
Non-Patent Citations (1)
| Title |
|---|
| 爱地传递LOVE: "生物玻璃", 《百度文库》 * |
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Application publication date: 20150701 |