CN104739876A - 一种改善水蛭粉口感的方法 - Google Patents

一种改善水蛭粉口感的方法 Download PDF

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CN104739876A
CN104739876A CN201510096363.4A CN201510096363A CN104739876A CN 104739876 A CN104739876 A CN 104739876A CN 201510096363 A CN201510096363 A CN 201510096363A CN 104739876 A CN104739876 A CN 104739876A
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powder
hirudo
milk
mouthfeel
hirudo powder
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马玉奎
刘金磊
石红艳
宋振华
方方
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Jinan Kangzhong Pharmaceutical Research and Development Co Ltd
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Jinan Kangzhong Pharmaceutical Research and Development Co Ltd
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Abstract

本发明涉及一种改善水蛭粉口感的方法,其特征在于:取水蛭粉,用牛奶调匀后服用。该方法在保持水蛭粉原有疗效的前提下,口服异味小,口感好,病人的顺应性高。

Description

一种改善水蛭粉口感的方法
发明领域
本发明涉及药品,特别涉及一种改善水蛭粉口感的方法,属医药技术领域。
背景技术
水蛭始载于《神农本草经》,2010 年版《中华人民共和国药典》一部收载供药用的为水蛭科动物蚂蟥、水蛭或柳叶蚂蟥的干燥全体。水蛭具逐恶血瘀血月闭,破血瘕积聚的功效,临床上可用于脑血管疾病,精液不化,前列腺肥大,子宫卒中综合征等多种疾病的治疗。
现代研究表明,水蛭粉可降低大鼠体质量,显著降低大鼠脂肪指数,有一定减肥作用,可减少体内脂肪沉积,降低脂质,改善机体代谢紊乱,可减轻氧化损伤,抑制炎症反应,延缓动脉粥样硬化病变的进展。文献报道,水蛭粉治疗高血压性脑出血疗效显著,可明显改善缺血性脑卒中患者的血液流变学和血脂,疗效可靠。
水蛭粉用温水冲服,异味特重,口感很差,直接影响病人的顺应性。《山东省中药饮片炮制规范》在用法用量项下记载“水蛭粉宜装胶囊吞服”,但“装胶囊”在家庭操作既不方便,又无法保证质量。提供一种改善水蛭粉口感的方法,十分必要。
发明内容
本发明的目的是提供一种改善水蛭粉口感的方法。
本发明通过以下技术方案实现:
一种改善水蛭粉口感的方法,其特征在于:取水蛭粉,用牛奶调匀后服用。
本发明的一种改善水蛭粉口感的方法,其特征在于替换为:取水蛭粉,加入奶粉,用水调匀后服用。
本发明的水蛭是指《中华人民共和国药典》2010 年版一部收载的供药用的水蛭,为水蛭科动物蚂蟥、水蛭和柳叶蚂蟥。
至此完成了本发明,本发明的服用方法,在保持水蛭粉原有疗效的前提下,口服异味小,病人的顺应性高。
下面试验例旨在进一步说明本发明的有益之处,而非对本发明的限制。
试验例一、不同服用方法口感比较
1、服用方法 分为两种:一种取水蛭粉,用温牛奶调匀后服用;一种取水蛭粉,用温水调匀后服用。
2、评价方法 在药物的口感评价中,感官评价起着主导作用,而人的感觉受主观因素影响大,语言表达感觉具有模糊性,很难用精准的数据表达。所以,本实验由30人组成评议组,每人分别按两种方法口服,对口感用“很好”、“较好”、“可以接受”、“较差”、“很差”等模糊概念来评价。
3、评价结果 见表1
表1   不同服用方法口感比较
  很好 较好 可以接受 较差 很差
用温牛奶调服 0人 7人 10人 13 0人
用温水调服 0人 0人 0人 4人 26人
结果显示,水蛭粉用温牛奶调匀后服用口感明显改善。
试验例二、水蛭粉不同服用方法对高脂饮食兔血脂水平的影响
选择体质健康伊拉肉兔120只,随机分成4组,每组30只,即空白组(饲喂基础饲料)、高脂组(饲喂高脂饲料)、牛奶调服组(饲喂高脂饲料+每日灌胃给温牛奶调匀的水蛭粉,1次0.1g/kg)、水调服组(饲喂高脂饲料+每日灌胃给温水奶调匀的水蛭粉,1次0.1g/kg)。空白组、高脂组每日灌胃给等体积的温水。实验第30d采血,测定血清中总胆固醇、甘油三脂、高密度脂蛋白胆固醇(高密度)、低密度脂蛋白胆固醇含量(低密度)。结果见表2
表2  水蛭粉不同服用方法对高脂饮食兔血脂水平的影响
  空白组 高脂组 牛奶调服 水调服组
总胆固醇 2.082±0.176 3.892±0.369 2.247±0.210 2.247±0.235
甘油三脂 0.767±0.245 1.914±0.047 0.793±0.175 0.793±0.182
高密度 1.038±0.096 1.320±0.253 1.184±0.082 1.184±0.080
低密度 0.635±0.236 1.745±0.103 0.751±0.073 0.751±0.076
结果表明,高脂饲料可以使兔血脂水平发生紊乱,在饲喂高脂饲料的同时加喂水蛭粉能够改善高脂饲料兔的血脂水平,牛奶调服和水调服作用相当。说明牛奶调服保持了原有疗效。
具体实施方式
实施例1
取水蛭粉2g,用5ml牛奶调匀, 口服异味小,口感好。
实施例2
取水蛭粉2g,用10ml牛奶调匀, 口服异味小,口感好。
实施例3
取水蛭粉2g,加入奶粉用2g,加入温水调匀,口服无异味,口感好。
实施例4
取水蛭粉2g,加入奶粉用10g调匀,口服无异味,口感好。
实施例5
取水蛭粉2g,用50ml牛奶调匀, 口服无异味,口感好。

Claims (2)

1.一种改善水蛭粉口感的方法,其特征在于:取水蛭粉,用牛奶调匀后服用。
2.根据权利要求1的一种改善水蛭粉口感的方法,其特征在于替换为:取水蛭粉,加入奶粉,用水调匀后服用。
CN201510096363.4A 2015-03-05 2015-03-05 一种改善水蛭粉口感的方法 Pending CN104739876A (zh)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103891895A (zh) * 2012-12-31 2014-07-02 内蒙古伊利实业集团股份有限公司 含有地龙蛋白的液态乳制品及其制备方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103891895A (zh) * 2012-12-31 2014-07-02 内蒙古伊利实业集团股份有限公司 含有地龙蛋白的液态乳制品及其制备方法

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