CN104739448B - A kind of ultrasonic imaging method and device - Google Patents

A kind of ultrasonic imaging method and device Download PDF

Info

Publication number
CN104739448B
CN104739448B CN201510158465.4A CN201510158465A CN104739448B CN 104739448 B CN104739448 B CN 104739448B CN 201510158465 A CN201510158465 A CN 201510158465A CN 104739448 B CN104739448 B CN 104739448B
Authority
CN
China
Prior art keywords
matrix
vectorial
ultrasonic
data
signal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201510158465.4A
Other languages
Chinese (zh)
Other versions
CN104739448A (en
Inventor
王丛知
彭玺
梁栋
郑海荣
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shenzhen Institute of Advanced Technology of CAS
Original Assignee
Shenzhen Institute of Advanced Technology of CAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shenzhen Institute of Advanced Technology of CAS filed Critical Shenzhen Institute of Advanced Technology of CAS
Priority to CN201510158465.4A priority Critical patent/CN104739448B/en
Publication of CN104739448A publication Critical patent/CN104739448A/en
Application granted granted Critical
Publication of CN104739448B publication Critical patent/CN104739448B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4411Device being modular
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/06Measuring blood flow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/06Measuring blood flow
    • A61B8/065Measuring blood flow to determine blood output from the heart
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/52Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/5207Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of raw data to produce diagnostic data, e.g. for generating an image

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Measurement Of Velocity Or Position Using Acoustic Or Ultrasonic Waves (AREA)

Abstract

The present invention relates to a kind of ultrasonic imaging method and device, wherein, the method includes:Obtain N × K very first time delayed data tn,k;Obtain D × K the second time delay data td,k;By the ultrasonic echo rf digital signal, accordingly matrixing is that length is the vectorial s of D × K;Using the corresponding second time delay data t of data point d of k-th passage in the vectorial sd,kAnd corresponding very first time delayed data t under same channelsn,kDetermine matrix M;Wherein, the matrix M is sparse matrix;Equation group is set up according to the vectorial s and the matrix M;Wherein, the equation group is:S=MI;I represents that the scatter intensity distribution of scattering, length are the vector of N;The equation group is solved by compressed sensing algorithm, vectorial I is obtained;According to the ultrasonoscopy that the vectorial I determines to want.

Description

A kind of ultrasonic imaging method and device
Technical field
The present invention relates to medical imaging technology field, more particularly to a kind of ultrasonic imaging method and device.
Background technology
Medical ultrasound image technology by over half a century development, because its is real-time, it is high to soft tissue taste, The advantages of easy to use and good economy performance, have become most widely used image technology and clinical various diseases in clinical medicine The prefered method of diagnosis.
The frame frequency of conventional ultrasound imaging is very low, generally in more than ten frames between tens frames.For high rigidity tissue elasticity into Picture, main artery high speed blood flow imaging, cardiac imaging and follow the trail of the imageable target such as acoustic contrast agent state change quickly move because And the application field of high frame frequency is needed, the frame frequency of conventional ultrasound imaging cannot much meet needs.
Plane of ultrasound ripple imaging technique includes the transmitting of plane of ultrasound ripple and corresponding ultrasonic echo beam-forming technology, ultrasound Traditional ultrasonic imaging frame frequency (generally more than ten frames to tens frames) can be improved hundred times by imaging technique, reach 10000~ 20000 frames.The general all array elements by linear array transducer of the method are all used to launch, using no relative time delay from each other Identical voltage impulses, while encouraging each array element of linear array transducer to produce what edge was propagated forward perpendicular to transducer face direction Plane of ultrasound ripple;When receiving echo-signal, using DAS (Delay and Sum, time delay superposition based on image slices vegetarian refreshments position Method) beam-forming technology one width two dimensional image of formation.So, it is only necessary to which once transmitting/reception can complete a two-dimensional imaging, Drastically increase imaging frame frequency.But, because when using plane wave imaging technique, ultrasonic energy is evenly distributed in entirely Two-dimensional imaging plane, understands aliasing together, by each channel reception, it is difficult to distinguish from the echo of different scattering reflection.Therefore, The image obtained by common Beamforming Method occurs apparent artifact interference.
To solve this problem, multi-angle coherent superposition imaging method is suggested.The method is from 2N+1 (N be a certain positive integer) (one of angle is the usually used angle perpendicular to surface of ultrasonic transducer to individual angle, and other 2N angle is around this Individual vertical angle in symmetrical shape be distributed, such as -2 °, -1 °, 0 °, 1 °, 2 °) transmitting plane of ultrasound ripple and equally using based on scheme As the DAS beam-forming technologies of pixel position obtain 2N+1 width two dimensional images, these images are overlapped, equivalent to from many Relevant enhancing is realized between the plane of ultrasound ripple of individual angular emission, is produced similar to the effect for focusing on, it is achieved thereby that image The enhancing of resolution ratio and contrast.N values are bigger, and the raising effect to resolution ratio and contrast is more notable.Using this technology, High-spatial and temporal resolution is had been realized in, the dynamic change produced by the response brain activity of full cerebral microvascular can be carried out in real time The new technology of imaging --- ultrasonic cerebral function imaging technology (functional ultrasound, fUS).Up to KHz quantity The frame frequency imaging effect of level, is the key of research trends blood flow situation of change.Additionally, the technology is also apply to multiple biological doctors Learn in the forward position research direction of ultrasonics, such as real-time three-dimensional ultrasonography, high velocity Doppler blood flow flow field velocity are scattered in picture, two Real-time elastogram, heart, main artery strain imaging etc. are tieed up, with very wide application prospect.But, multi-angle is relevant folded Plus imaging method is equivalent to frame frequency is again reduced, for example, using common plane of ultrasound wave imaging method, it is possible to achieve 10000 Frame frame frequency per second, but in order to improve the resolution ratio and contrast of image, be changed to using multi-angle coherent superposition imaging method, by 51 The transmitting of individual angle/reception result synthesis piece image, frame frequency has dropped down to per second less than 200 frames.Therefore, multi-angle is concerned with The range of application of stacking image method is seriously restricted.
In sum, how while ensureing that frame frequency does not decline, the resolution ratio and contrast of image are improved as much as possible, As the major issue that ultrasonic imaging needs to solve.
The content of the invention
To solve the problems, such as above-mentioned technology, the present invention proposes a kind of ultrasonic imaging method and device.
To achieve the above object, the invention provides a kind of ultrasonic imaging method, the method includes:
Obtain N × K very first time delayed data tn,k;Wherein, the very first time delayed data tn,kIt is ultrasonic signal Since the ultrasound emission moment, by n-th scattering of scattering, k-th channel position of ultrasound transducer array is returned Total time delay;N represents the pixel number of the ultrasonoscopy wanted, and K represents array element number in ultrasound transducer array; N represents some scattering, scatters sub- n=1,2 ... ..., N;K represents some passage in ultrasound transducer array, k=1, 2 ... ..., K;
Obtain D × K the second time delay data td,k;Wherein, the second time delay data td,kFor known from super Sound emission moment, the elapsed time postpones, and starts to sample ultrasonic echo radiofrequency signal, obtains ultrasonic echo radio frequency number Word signal, the moment of k-th channel reception to d-th data point of the ultrasonic echo rf digital signal believes relative to ultrasound The time delay of number delivery time;D represents the sampling number of each passage, and d represents a channel reception to ultrasonic echo radio frequency number The a certain data point of word signal, d=1,2 ... ..., D;
By the ultrasonic echo rf digital signal, accordingly matrixing is that length is the vectorial s of D × K;
Using the corresponding second time delay data t of data point d of k-th passage in the vectorial sd,kAnd it is identical logical Corresponding very first time delayed data t under roadn,kDetermine matrix M;Wherein, the matrix M is sparse matrix;
Equation group is set up according to the vectorial s and the matrix M;Wherein, the equation group is:S=MI;I dissipates for expression The length for penetrating the scatter intensity distribution of son is the vector of N;
The equation group is solved by compressed sensing algorithm, vectorial I is obtained;
According to the ultrasonoscopy that the vectorial I determines to want.
Preferably, the step of determination matrix M includes:
Data point d to k-th passage sets up the vectorial m that length is N, obtains D × K vector m;In the vectorial m Each element determines that method is:If the corresponding second time delay data t of the data point d of k-th passaged,kAnd it is identical logical Corresponding very first time delayed data t under roadn,kMeetThen from n-th ultrasonic echo of scattering son scattering Information is included in k-th data point d of passage, then nth elements are set to 1 in vector m, otherwise, are set to 0;
D × K vector m is configured to the matrix M of D × K row, N row.
Preferably, the ultrasonic signal is plane of ultrasound ripple signal.
Preferably, the very first time delayed data tn,kExpression formula be:
Wherein, k-th locus coordinate of passage is (xk,0);N-th scattering on the ultrasonoscopy wanted Locus coordinate be (xn,zn);C represents sound wave spread speed in media as well;X directions are the widths of ultrasonoscopy, Z directions are the depth directions of ultrasonoscopy.
Preferably, the ultrasonic signal is ultrasonic convex surface ripple signal, ultrasonic concave surface ripple signal.
Preferably, the second time delay data td,kExpression formula be:
td,k=t0+(d-1)/fs
Wherein, t0Represent since the ultrasound emission moment carries out sampling instant to ultrasonic echo radiofrequency signal when Between length of delay, fsRepresent sample frequency.
Preferably, it is described to include the step of solved by compressed sensing algorithm to the equation group:
If vector I is sparse, equation group s=MI is solved by compressed sensing algorithm, that is, metThe I values of condition are the optimal solution of equation group;Wherein, β represents permission how many noise contribution In the presence of;S.t. it is the formal notation for representing logical relation;
Otherwise, sparse transformation is carried out to vectorial I;Equation group s=MI is solved by compressed sensing algorithm, that is, is metThe I values of condition are the optimal solution of equation group;Wherein, Ψ represents sparse transformation matrix, β Representing allows how many noise contributions to exist;S.t. it is the formal notation for representing logical relation.
Preferably, the compressed sensing algorithm be matching pursuit algorithm, Bregman algorithms, operator/variable splitting algorithm, Fixing point continuation algorithm, L1 norm magics algorithm, Newton tangential method.
Preferably, the step of ultrasonoscopy that the determination is wanted, includes:
Vectorial I is transformed to image array Φ;Wherein, described image matrix Φ is a NxRow NzCapable matrix;NxRepresent The number of x directions epigraph pixel, N in three-dimensional system of coordinatezRepresent the number of z directions epigraph pixel in three-dimensional system of coordinate, N= Nx×Nz
To the matrix Φ treatment, the ultrasonoscopy wanted is obtained;Wherein, the method for the treatment of includes:The number of winning the confidence Envelope, log-compressed, adjustment and carry out digital scan conversion at image display dynamic range.
To achieve the above object, present invention also offers a kind of supersonic imaging device, the device includes:
Very first time delayed data determining unit, for obtaining N × K very first time delayed data tn,k;Wherein, it is described Very first time delayed data tn,kIt is ultrasonic signal since the ultrasound emission moment, by n-th scattering of scattering, returns Total time delay of k-th channel position of ultrasound transducer array;N represents the pixel number of the ultrasonoscopy wanted, K Represent array element number in ultrasound transducer array;N represents some scattering, scatters sub- n=1,2 ... ..., N;K represents ultrasound Some passage, k=1,2 ... ..., K in transducer array;
Second time delay data determination unit, for obtaining D × K the second time delay data td,k;Wherein, it is described Second time delay data td,kFor known since the ultrasound emission moment, the elapsed time postpones, and starts to believe ultrasonic echo radio frequency Number sampled, obtained ultrasonic echo rf digital signal, k-th channel reception to the ultrasonic echo rf digital signal Time delay of d-th data point relative to ultrasonic signal delivery time;D represents the sampling number of each passage, and d represents that one leads to Road receives a certain data point of ultrasonic echo rf digital signal, d=1,2 ... ..., D;
Converter unit, for by the ultrasonic echo rf digital signal accordingly matrixing be length for D × K to Amount s;
Matrix determining unit, for corresponding second time delays of data point d using k-th passage in the vectorial s Data td,kAnd corresponding very first time delayed data t under same channelsn,kDetermine matrix M;Wherein, the matrix M is sparse Matrix;
Model sets up unit, for setting up equation group according to the vectorial s and the matrix M;Wherein, the equation group For:S=MI;I represents that the scatter intensity distribution of scattering, length are the vector of N;
Unit is solved, for being solved by compressed sensing algorithm to the equation group, vectorial I is obtained;
Ultrasound imaging unit, for the ultrasonoscopy for determining to want according to the vectorial I.
Preferably, the matrix determining unit includes:
Vector sets up module, and the vectorial m that length is N is set up for the data point d to k-th passage, obtain D × K to Amount m;Each element in the vectorial m determines that method is:If corresponding second time delays of the data point d of k-th passage Data td,kAnd corresponding very first time delayed data t under same channelsn,kMeetThen from n-th scattering The ultrasonic echo information of son scattering is included in k-th data point d of passage, then nth elements are set to 1 in vector m, otherwise, It is set to 0;
Constructing module, the matrix M for D × K vector m to be configured to D × K row, N row.
Preferably, the ultrasonic signal of the supersonic imaging device treatment is plane of ultrasound ripple signal.
Preferably, the very first time delayed data t that the very first time delayed data determining unit is obtainedn,kExpression formula For:
Wherein, k-th coordinate of passage is (xk,0);The coordinate of n-th scattering of the ultrasonoscopy wanted is (xn, zn);C represents sound wave spread speed in media as well.
Preferably, the ultrasonic signal of the supersonic imaging device treatment is ultrasonic convex surface ripple signal, ultrasonic concave surface ripple signal.
Preferably, the second time delay data t that the second time delay data determination unit is obtainedd,kExpression formula For:
td,k=t0+(d-1)/fs
Wherein, t0Represent time-delay value, fsRepresent sample frequency.
Preferably, the solution unit includes:
First solves module, for the vectorial I it is sparse when, equation group s=MI is asked by compressed sensing algorithm Solution, that is, meetThe I values of condition are the optimal solution of equation group;Wherein, how much β represents permission Noise contribution is present;S.t. it is the formal notation for representing logical relation;
Second solves module, for the vectorial I it is not sparse when, sparse transformation is carried out to vectorial I;Calculated by compressed sensing Method is solved to equation group s=MI, that is, meetThe I values of condition be equation group most Excellent solution;Wherein, Ψ represents sparse transformation matrix, and β represents that the how many noise contributions of permission are present;S.t. it is the public affairs for representing logical relation Formula symbol.
Preferably, it is described solve the compressed sensing algorithm that uses of unit for matching pursuit algorithm, Bregman algorithms, operator/ Variable splitting algorithm, fixing point continuation algorithm, L1 norm magics algorithm, Newton tangential method.
Preferably, the ultrasound imaging unit includes:
Conversion module, for vectorial I to be transformed into image array Φ;Wherein, described image matrix Φ is a NxRow Nz The matrix of row;NXThe number of x directions epigraph pixel in three-dimensional system of coordinate is represented, Nz represents the upper figure in z directions in three-dimensional system of coordinate As the number of pixel, N=Nx×Nz
Processing module, for the matrix Φ treatment, obtaining the ultrasonoscopy wanted;Wherein, the side for the treatment of Method includes:Take signal envelope, log-compressed, adjustment image display dynamic range and carry out digital scan conversion.
Compared with prior art, the present invention realizes a ultrasound emission/reception and just can complete a two-dimensional imaging, Theoretic most fast frame frequency is reached, while considerably improving the resolution ratio and contrast of image.And, it can both be applied In the imaging of plane of ultrasound ripple, it may have be applied to the potentiality of the ultrasonic imaging of other nonplanar wave radiation patterns, be medical ultrasonic The development of imaging technique provides a new direction, and international monopoly monopolization is broken to China's medical ultrasonic image equipment, realizes The advanced technology breakthrough for grasping independent intellectual property right is significant.
Brief description of the drawings
In order to illustrate more clearly about the embodiment of the present invention or technical scheme of the prior art, below will be to embodiment or existing The accompanying drawing to be used needed for having technology description is briefly described, it should be apparent that, drawings in the following description are only this Some embodiments of invention, for those of ordinary skill in the art, on the premise of not paying creative work, can be with Other accompanying drawings are obtained according to these accompanying drawings.
Fig. 1 is traditionally ultrasonic imaging principle schematic;
Fig. 2 is a kind of ultrasonic imaging method flow chart proposed by the present invention;
Fig. 3 is the simulation experiment result figure being imaged to the sparse imitative body of point-like using the technical program;
Fig. 4 is the simulation experiment result figure being imaged to the sparse imitative body of point-like using traditional time delay addition method;
Fig. 5 is the simulation result figure being imaged to non-sparse imitative body using the technical program;
Fig. 6 is the simulation result figure being imaged to non-sparse imitative body using traditional time delay addition method;
Fig. 7 is renal tissue section original image;
Fig. 8 is the imaging results figure obtained using the technical program;
Fig. 9 is the imaging results figure obtained using traditional time delay addition method;
Figure 10 is a kind of supersonic imaging device block diagram proposed by the present invention.
Specific embodiment
Principle of the invention and spirit are described below with reference to some illustrative embodiments.It should be appreciated that providing this A little implementation methods are used for the purpose of better understood when those skilled in the art and then realizing the present invention, and not with any Mode limits the scope of the present invention.Conversely, these embodiments are provided so that the disclosure is more thorough and complete, and energy It is enough that the scope of the present disclosure is intactly conveyed into those skilled in the art.
Art technology technical staff knows, embodiments of the present invention can be implemented as a kind of system, device, equipment, Method or computer program product.Therefore, the disclosure can be implemented as following form, i.e.,:It is complete hardware, complete soft Part (including firmware, resident software, microcode etc.), or the form that hardware and software is combined.
According to the embodiment of the present invention, it is proposed that a kind of ultrasonic imaging method and device.
Herein, it is to be understood that in involved term:
1st, ultrasonic imaging:By taking linear array ultrasound transducer as an example, as shown in figure 1, linear array transducer possess K can be independent The array element of transmitting/reception, corresponding to K ultrasound emission passage and signal receiving channel.During ultrasound emission, using multiple passages Delay emission, makes the ultrasonic signal of different passages while reaching focal position, forms transmitting focusing;When receiving echo, to receiving To signal carry out similar time delay, by the different channel receptions returned from same reflection thing to signal be accumulated in together, shape Into collectiong focusing.So once launch and once receive, a scan line can be formed.Usual ultrasonic imaging is all swept using electronics The mode retouched, carries out P focus emission/reception to obtain P bar scan lines, then by these scan conversions into the complete two dimension of a width Image.
2nd, compressed sensing (Compressive sensing), also referred to as compression sampling (Compressive Sampling), sparse sampling (Sparse sampling), compression sensing., used as a new sampling theory, it is by opening for it The sparse characteristic of signalling, under conditions of much smaller than Nyquist sample rates, the discrete sample of signal is obtained with stochastical sampling, Then the perfect reconstruction signal of non-linear algorithm for reconstructing is passed through.
Additionally, any number of elements in accompanying drawing is used to example and unrestricted, and any name is only used for distinguishing, Without any limitation.
Below with reference to some representative embodiments of the invention, principle of the invention and spirit are explained in detail.
Summary of the invention
In recent years, some papers on the plane of ultrasound wave imaging method based on compressed sensing successively send out both at home and abroad Table.These methods are all divided into two steps:
(1) each pixel of image is considered as a grid node in two dimensional surface, it is assumed that at each grid node The scattering of incident ultrasound can be all caused in the presence of scattering, echo is formed.Then it is believed that the ultrasound that we want is schemed The actual reflection of picture is the distribution that sub scattering strength is scattered on grid node in two dimensional surface.
Firstly, it is necessary to set up on reflection ultrasonic echo radiofrequency signal s and grid node scatter between sub- scatter intensity distribution I The Mathematical Modeling of relation, forms the equation group of following form:
S=MI
Wherein, matrix M is encoder matrix (encoding matrix).But it is under normal circumstances one to solve equation group Ill-posed problem, i.e. equation quantity are less than unknown number quantity, it is impossible to try to achieve unique solution.
(2) as I sparse (sparse), i.e., when nonzero element quantity therein is much smaller than neutral element quantity, then can lead to Overcompression cognitive method is solved to above-mentioned equation group:
Wherein β reflects us allows how many noise contributions to exist.
For ultrasonic imaging, in (1st) step, how the physical principle followed according to it, foundation can use up The Mathematical Modeling of relation between s and I may truly be reflected, and set up the encoder matrix M for being easy to complete follow-up iterative calculation accordingly, It is the key for determining ultrasonic imaging quality and imaging method practicality.And in (2nd) step, the specific calculating side of solving equations Method has had the iterative numerical approach of many maturations available, is not belonging to the emphasis of the application elaboration.
For scattering sub- scatter intensity distribution in the reflection ultrasonic echo radiofrequency signal described in step (1) and grid node Between relation Mathematical Modeling, that has delivered mainly has following two:
The first Mathematical Modeling:The more complicated model of the compressibility distribution situation based on medium to be imaged
The final form of the first Mathematical Modeling is:
Wherein, G is a NelNkThe encoder matrix of × N, NelIt is the port number of ultrasound transducer array reception echo-signal, NkThe ultrasound echo signal in broadband is divided into N by fingerkIndividual discrete wave number kl, 1≤l≤Nk, N=Nx×NzIt is total pixel of image Number (or perhaps grid node number), Nx, NzIt is respectively x directions (width) and z directions (depth direction) epigraph pixel Line number and columns.Each element definition in matrix G is:
Wherein, m represents m-th array element on transducer, 1≤m≤Nel, i represents the ith pixel on image, Represent the acoustic pressure of incident ultrasound, rel,mRepresent m-th locus of array element, r on ultrasonic transduceri Represent the position of ith pixel on image, gl(rel,m-ri) be open space Green's function, be defined as:
Wherein, j represents imaginary part,It is the Equations of The Second Kind Hankel functions of zeroth order.pscRepresent ultrasonic echo radiofrequency signal, γκ Represent the compressibility of the medium to be imaged distribution situation (compressibility of medium be determine its sound scattering intensity it is main because Element).
Second Mathematical Modeling:Fairly simple model based on frequency-region signal time delay
The final form of second Mathematical Modeling is:X (ω)=A (ω) S (ω)
Processed by being then based on frequency-region signal, actually taken ω=2 π f0, wherein, f0It is the ultrasonic transduction for being used The emission center frequency of device.X is that, by the ultrasonic echo radiofrequency signal after Short Time Fourier Transform, S is the scattering to be imaged Sub- scattering strength corresponds to f on frequency domain0Mapping, A for K × L the encoder matrix being made up of time delay data, definition For:
[A(ω)k]i=exp [j ω τki)]
Wherein, K be ultrasound transducer array receive echo-signal port number, L for image total pixel count (in other words It is grid node number), 1≤k≤K, 1≤i≤L, ρiA pixel (or grid node) on image is represented,The echo-signal that expression sends from certain pixel reaches certain ultrasound transducer array and leads to The time delay in road, rkThe locus of certain ultrasound transducer array passage is represented,Represent certain pixel ρiSpace Position.It may be noted that X be intercepted out from whole ultrasonic echo radiofrequency signals it is a bit of carry out short time discrete Fourier transform after obtain Frequency-region signal, if therefore whole ultrasonic echo radiofrequency signal is divided into Q section, to complete all to be imaged, it is necessary to will be follow-up Solution procedure is repeated Q times.
After setting up above-mentioned two model, solving equations are carried out by compression sensing method, it is possible to solve γκ(first Plant Mathematical Modeling) or S (second Mathematical Modeling), then by it from the matrix that vector transformation is correspondence image pixel quantity, Our the desired images for obtaining can be just shown as.
Above-mentioned two reflects relation between sub- scatter intensity distribution is scattered on ultrasonic echo radiofrequency signal and grid node Mathematical Modeling, respectively there is its limitation.
The foundation of the first Mathematical Modeling, is gone out from the Mathematical Modeling for being proved to more accurately acoustic propagation and scattering Hair, advantage be can more real reflection sound various physical phenomenons in media as well, but shortcoming is also clearly, is exactly model It is excessively complicated.The size of encoder matrix G is excessively huge, it is necessary to take a large amount of internal memories, while also resulting in follow-up solution procedure Amount of calculation is very huge.With the imaging experiment data instance carried out in its paper, work as Nx=400, Nz=600, Nel=128, Nk= When 1000, the internal memory that matrix G takes is up to 458GB.Therefore, to realize the algorithm, all have to again be counted using when calling G every time Calculate the method for its each element numerical value to carry out, significantly increase amount of calculation.And, actually above-mentioned parameter value at all cannot The need for meeting normal medical ultrasound image, if imaging depth is more than 5cm, NzValue generally all more than 3000, therefore EMS memory occupation amount will be also further added by 5 times, be not completely the task that common computer can undertake.
The first Mathematical Modeling due to only considering the time delay of ultrasonic echo radiofrequency signal, while in only considering ultrasound Heart tranmitting frequency f0Greatly contracted without other frequency contents of consideration signal, therefore the scale of its encoder matrix A (ω) for being used It is small.But, the model still has following problem.First, all elements of matrix A (ω) are all non-zeros, and X is from complete The a bit of frequency-region signal for carrying out and being obtained after short time discrete Fourier transform is intercepted out in portion's ultrasonic echo radiofrequency signal, if all ultrasounds Echo radiofrequency signal is divided into Q sections, then to complete all imagings, it is necessary to follow-up solution procedure is repeated Q times, therefore after carrying out Amount of calculation is still very big during continuous matrix multiplication operation.Secondly, for convenience time delay calculating is carried out to signal, the model All computings all carried out in frequency domain.This is accomplished by, first by the ultrasonic echo radiofrequency signal of time domain, becoming by Fourier in short-term Change and be transformed into frequency domain.This process not only increases amount of calculation, can also introduce due to the leakage errors of the limited generation of signal length And leakage error, and then have influence on final image quality.
The purpose of the technical program is relative to the first Mathematical Modeling, encoder matrix to be simplified as far as possible, when reducing computing Memory storage space and amount of calculation;Relative to the second Mathematical Modeling, it is to avoid use Fourier transform and frequency-domain calculations;Ensureing Frame frequency high and while compared with high imaging quality, the hardware computing platform that realization only needs to reduced levels can just be carried out using this method Imaging, is easy to implement the industry conversion of the technical program.
The technical program by ultrasonic echo radiofrequency signal relative to ultrasonic wave x time time delay information with dissipate The relation penetrated between the spatial positional information of sub- distribution, sets up the encoder matrix M in time domain expression, forms following reflection ultrasound The equation group s=MI of relation between sub- scatter intensity distribution I is scattered on echo rf digital signal s and grid node;Due to this When encoder matrix M be a sparse matrix, therefore internal memory of its occupancy can be greatly lowered by way of sparse expression deposit Storage space, while amount of calculation when using its computing is also very low.Finally, by ripe compressed sensing algorithm to above-mentioned side Journey group is solved, and obtains vectorial I, as desired to obtain by it from the matrix that vector transformation is correspondence image pixel quantity The ultrasonoscopy for obtaining.
After general principle of the invention is described, lower mask body introduces various non-limiting embodiment party of the invention Formula.
Application scenarios overview
Ultrasonic imaging is using ultrasonic acoustic beam scanning human body, by the reception to reflected signal, treatment, to obtain internal device The image of official.Conventional ultrasonic instrument has various:A types (amplitude mode) are to represent the strong of reflected signal with the height of wave amplitude It is weak, it is shown that a kind of " echogram ".M types (spot scan type) are represented from shallow to deep locus, water with vertical direction Square to the time is represented, movement profiles of the luminous point in different time are shown as.Above amphitypy is one-dimensional display, range of application It is limited.Type B (brightness mode) is tomosonography instrument, referred to as " B ultrasonic ".It is that reception signal is represented with the different luminous point of brightness Power, when probe is moved along horizontal level, luminous point on display screen also synchronizing moving in the horizontal direction connects luminescent spot track It is two-dimensional imaging into the sectional drawing that ultrasonic acoustic beam is scanned.Because Type B ultrasonic image is clear, directly perceived, stereovision is strong, therefore is facing Bed is widely used.It is that .C types are made then with the scan mode of approximate TV according to principle of Doppler as D types, shows vertical Directly in the cross section acoustic image of acoustic beam.In recent years, ultrasonic imaging technique is continued to develop, and such as GTG show and colored display, real-time Imaging, ultrasound holography, penetration ultrasonic imaging, ultrasonoscope and machine tomography rubbish shadow, three-dimensional imaging, ultrasonic imaging in body cavity Deng.
Ultrasonic imaging method is commonly used to judge the position of internal organs, size, form, determines the scope and physical property of focus, The internal anatomy of some gland tissues is provided, differentiate fetus it is normal with it is abnormal, in ophthalmology, gynemetrics and cardiovascular system, digestion System, urinary system application it is quite varied.
The technical program enters row energization to ultrasound transducer array by computer controls ultrasound emission circuit first, and transmitting is super Acoustical signal.When each passage (each passage corresponds to an array element) of ultrasound transducer array is excited simultaneously, launch Ultrasonic signal, ultrasonic signal is propagated in media as well, is scattered, and forms ultrasound echo signal.Ultrasound echo signal is changed by ultrasound Energy device array received, forms ultrasonic echo radiofrequency signal, then by ultrasonic reception circuit sampling, forms ultrasonic echo RF digital letter Number.Ultrasonic echo rf digital signal is sent back in computer, and realizes ultrasonic imaging in a computer.
Illustrative methods
Next, being introduced to exemplary embodiment of the invention with reference to Fig. 2.
As shown in Fig. 2 being a kind of ultrasonic imaging method flow chart proposed by the present invention.The method includes:
Step 201):Obtain N × K very first time delayed data tn,k;Wherein, the very first time delayed data tn,kFor Ultrasonic signal, by n-th scattering of scattering, returns k-th of ultrasound transducer array since the ultrasound emission moment Total time delay of channel position;N represents the pixel number of the ultrasonoscopy wanted, and K is represented in ultrasound transducer array Array element number;N represents some scattering, scatters sub- n=1,2 ... ..., N;Some leads to during k represents ultrasound transducer array Road, k=1,2 ... ..., K;
Step 202):Obtain D × K the second time delay data td,k;Wherein, the second time delay data td,kFor Known the elapsed time postpones, and starts to sample ultrasonic echo radiofrequency signal since the ultrasound emission moment, obtains ultrasound and returns Ripple rf digital signal, the moment of k-th channel reception to d-th data point of the ultrasonic echo rf digital signal is relative In the time delay of ultrasonic signal delivery time;D represents the sampling number of each passage, and d represents that a channel reception is returned to ultrasound The a certain data point of ripple rf digital signal, d=1,2 ... ..., D;
Step 203):By the ultrasonic echo rf digital signal, accordingly matrixing is that length is the vectorial s of D × K;
Step 204):Using the corresponding second time delay data t of data point d of k-th passage in the vectorial sd,kWith And corresponding very first time delayed data t under same channelsn,kDetermine matrix M;Wherein, the matrix M is sparse matrix;
Step 205):Equation group is set up according to the vectorial s and the matrix M;Wherein, the equation group is:S=MI;I For the length for representing the scatter intensity distribution of scattering is the vector of N;
Step 206):The equation group is solved by compressed sensing algorithm, vectorial I is obtained;
Step 207):According to the ultrasonoscopy that the vectorial I determines to want.
This method is not limited to just in the imaging of plane of ultrasound ripple.If for example, ultrasound transducer array send be Convex surface ripple or concave surface ripple, as long as the case may be, changing above-mentioned calculating ultrasonic signal since the ultrasound emission moment, pass through The scattering of certain scattering is crossed, the very first time delayed data t of certain element position of ultrasound transducer array is returnedn,k's Computing formula.Other all sames.
So that ultrasonic signal is plane of ultrasound ripple signal as an example, it is known that ultrasound transducer array includes K array element, wherein kth The coordinate of individual array element is (xk,0).The pixel number (the grid node number for being divided to imaging plane) of the ultrasonoscopy wanted It is N=Nx×Nz, wherein, Nx、NzBe respectively x directions (width) and z directions (depth direction) epigraph pixel line number and Columns.The coordinate of the sub- n of scattering at some grid node is (xn,zn).Then have, ultrasonic signal since the ultrasound emission moment, By the scattering of this scattering, k-th element position of ultrasound transducer array is returned, total very first time delay is:
Wherein, c is sound wave spread speed in media as well.It is corresponding, N × K very first time delayed data can be obtained tn,k
It is known since the ultrasound emission moment, by t0Time delay, start to adopt ultrasonic echo radiofrequency signal Sample, sample frequency is fs, the sampling number of each passage is D, then d of k-th channel reception to ultrasonic echo radiofrequency signal At the time point of individual data, the time delay relative to the ultrasound emission moment is:
td,k=t0+(d-1)/fs
It is corresponding, D × K the second time delay data t can be obtainedd,k
Include for the present embodiment, the step of determine matrix M:
Data point d to k-th passage sets up the vectorial m that length is N, obtains D × K vector m;In the vectorial m Each element determines that method is:If the corresponding second time delay data t of the data point d of k-th passaged,kAnd it is identical logical Corresponding very first time delayed data t under roadn,kMeetThen from n-th ultrasonic echo of scattering son scattering Information is included in k-th data point d of passage, then nth elements are set to 1 in vector m, otherwise, are set to 0;
D × K vector m is configured to the matrix M of D × K row, N row.
It is described to include the step of solved by compressed sensing algorithm to the equation group for the present embodiment:
If vector I is sparse, equation group s=MI is solved by compressed sensing algorithm, that is, metThe I values of condition are the optimal solution of equation group;Wherein, β represents permission how many noise contribution In the presence of;S.t. it is the formal notation for representing logical relation;
Otherwise, sparse transformation is carried out to vectorial I;Equation group s=MI is solved by compressed sensing algorithm, that is, is metThe I values of condition are the optimal solution of equation group;Wherein, Ψ represents sparse transformation matrix, β Representing allows how many noise contributions to exist;S.t. it is the formal notation for representing logical relation.
For the technical program, ripe compressed sensing algorithm includes but is not limited to matching pursuit algorithm (matching Pursuitmethod), Bregman algorithms, operator/variable splitting algorithm (operator/variable splitting), Fixing point continuation algorithm (Fixed-point continuation), L1 norm magics algorithm (L1-magic), Newton tangential method Deng.
For the present embodiment, it is determined that want ultrasonoscopy the step of include:
Vectorial I is transformed to image array Φ;Wherein, described image matrix Φ is a NXThe matrix of row Nz row;NXRepresent The number of x directions epigraph pixel in three-dimensional system of coordinate, Nz represents the number of z directions epigraph pixel in three-dimensional system of coordinate, N= Nx×Nz;
To the matrix Φ treatment, the ultrasonoscopy wanted is obtained;Wherein, the method for the treatment of includes:The number of winning the confidence Envelope, log-compressed, adjustment and carry out digital scan conversion at image display dynamic range.
In the present embodiment, the technical program is verified using Field II ultrasonic imagings simulation software.Such as Fig. 3 It is shown, it is the simulation experiment result figure being imaged to the sparse imitative body of point-like using the technical program.As shown in figure 4, to adopt The simulation experiment result figure being imaged to the sparse imitative body of point-like with traditional time delay addition method (DAS).Can be with by contrast It was found that, the technical program can remove the horizontal artifact occurred in conventional method.
As shown in figure 5, being the simulation result figure being imaged to non-sparse imitative body using the technical program.As shown in fig. 6, It is the simulation result figure being imaged to non-sparse imitative body using traditional time delay addition method (DAS).By contrast it can be found that The technical program can obtain more preferable contrast, and can remove the artifact occurred in conventional method near field.
As shown in fig. 7, being renal tissue section original image.As shown in figure 8, being the imaging obtained using the technical program Result figure.As shown in figure 9, being the imaging results figure obtained using traditional time delay addition method (DAS).Found by contrast, this Image formed by technical scheme, shows that the profile of kidney, structure are apparent, and soft tissue level becomes apparent from, and contrast in tissue increases, And the artifact occurred in conventional method near field can be removed.
The technical program considers that ultrasonic echo radiofrequency signal, relative to the time delay of ultrasonic wave x time, does not differentiate between it In different frequency composition, it is all greatly simplified relative to the first Mathematical Modeling, the second Mathematical Modeling.The technical program returns ultrasound Ripple radiofrequency signal has been contacted relative to the time delay information of ultrasonic wave x time with the spatial positional information of scattering son distribution Come, by setting up more massive encoder matrix M, solve the time domain expression problem to signal time Delay computing, no longer need Carry out Fourier transform and calculated in frequency domain, it is to avoid because carry out Fourier transform and caused by calculation error.
Further, since the encoder matrix M that the technical program is set up is a sparse matrix, can be by sparse expression Mode is greatly lowered the memory storage space of its occupancy, while amount of calculation when using its computing is also very low.With us As a example by the simulation imaging experiment for carrying out, the data of ultrasonic echo radiofrequency signal points are 128 × 4364, and institute is into image pixel It is 256 × 3000 to count, then the size of matrix M is 558592 × 768000, it is assumed that all elements in matrix M are all 64bit Double-precision number, then it is 3423GB to need memory storage space.In fact, due to matrix M be it is sparse, nonzero element therein Quantity is 98 × 106, therefore when using sparse expression, the memory storage space of the actual occupancy of M is 1.57GB.Compared to first For Mathematical Modeling, if Nk1000 are taken, then its encoder matrix G needs 786GB memory storage spaces.It can be seen that the technical program institute The memory storage space of occupancy greatly reduces.
Compared to the second Mathematical Modeling, although its encoder matrix A only needs to the memory space of 786MB, but due to need by Whole ultrasonic echo radiofrequency signals are divided into Q sections, and the every one piece of data to intercepting out carries out short time discrete Fourier transform to obtain frequency domain Signal, and repeat follow-up solution calculating.Therefore, the second Mathematical Modeling in total amount of calculation still above the technical program (need certain overlap to improve the resolution ratio of depth direction, therefore number more than 4000 between former and later two segmentations of data The length at strong point at least needs to be divided into 100 sections).Additionally, the second Mathematical Modeling for convenience time delay is carried out to signal Calculate, all computings are all carried out in frequency domain.And Short Time Fourier Transform is calculated and not only increases amount of calculation, can also introduce due to letter Leakage errors and leakage error that number limited length is produced, and then have influence on final image quality.
It should be noted that although the operation of the inventive method is described with particular order in the accompanying drawings, this is not required that Or imply that these must be performed according to the particular order operates, or the operation having to carry out shown in whole could realize the phase The result of prestige.Additionally or alternatively, it is convenient to omit some steps, multiple steps are merged into a step to perform, and/or will One step is decomposed into execution of multiple steps.
Example devices
The device of exemplary embodiment of the invention is introduced below with reference to Figure 10.
As shown in Figure 10, a kind of supersonic imaging device block diagram proposed by the present invention.The device includes:
Very first time delayed data determining unit 101, for obtaining N × K very first time delayed data tn,k;Wherein, institute State very first time delayed data tn,kIt is ultrasonic signal since the ultrasound emission moment, by n-th scattering of scattering, then returns To total time delay of k-th channel position of ultrasound transducer array;N represents the pixel of the ultrasonoscopy wanted Number, K represents array element number in ultrasound transducer array;N represents some scattering, scatters sub- n=1,2 ... ..., N;K is represented Some passage, k=1,2 ... ..., K in ultrasound transducer array;
Second time delay data determination unit 102, for obtaining D × K the second time delay data td,k;Wherein, institute State the second time delay data td,kFor known since the ultrasound emission moment, the elapsed time postpones, and starts to ultrasonic echo radio frequency Signal is sampled, and obtains ultrasonic echo rf digital signal, the ultrasonic echo radiofrequency signal after k-th channel reception to sampling Time delay of d-th data point relative to ultrasonic signal delivery time;D represents the sampling number of each passage, and d represents one Channel reception to ultrasonic echo rf digital signal a certain data point, d=1,2 ... ..., D;
Converter unit 103, for accordingly matrixing to be that length is D × K by the ultrasonic echo rf digital signal Vectorial s;
Matrix determining unit 104, prolongs for data point d corresponding second times using k-th passage in the vectorial s Slow data td,kAnd corresponding very first time delayed data t under same channelsn,kDetermine matrix M;Wherein, the matrix M is dilute Dredge matrix;
Model sets up unit 105, for setting up equation group according to the vectorial s and the matrix M;Wherein, the equation Group is:S=MI;I represents that the scatter intensity distribution of scattering, length are the vector of N;
Unit 106 is solved, for being solved by compressed sensing algorithm to the equation group, vectorial I is obtained;
Ultrasound imaging unit 107, for the ultrasonoscopy for determining to want according to the vectorial I.
For the present embodiment, the matrix determining unit 104 includes:
Vector sets up module, and the vectorial m that length is N is set up for the data point d to k-th passage, obtain D × K to Amount m;Each element in the vectorial m determines that method is:If corresponding second time delays of the data point d of k-th passage Data td,kAnd corresponding very first time delayed data t under same channelsn,kMeetThen from n-th scattering The ultrasonic echo information of son scattering is included in k-th data point d of passage, then nth elements are set to 1 in vector m, otherwise, It is set to 0;
Constructing module, the matrix M for D × K vector m to be configured to D × K row, N row.
For the present embodiment, the ultrasonic signal of the supersonic imaging device treatment is plane of ultrasound ripple signal.It is this In the case of, the very first time delayed data t that the very first time delayed data determining unit is obtainedn,kExpression formula be:
Wherein, k-th coordinate of passage is (xk,0);The coordinate of n-th scattering of the ultrasonoscopy wanted is (xn, zn);C represents sound wave spread speed in media as well.
This method is not limited to just in the imaging of plane of ultrasound ripple.If for example, ultrasound transducer array send be Convex surface ripple or concave surface ripple, as long as the case may be, changing above-mentioned calculating ultrasonic signal since the ultrasound emission moment, pass through The scattering of certain scattering is crossed, the very first time delayed data t of certain element position of ultrasound transducer array is returnedn,k's Computing formula.Other all sames.
The second time delay data t that the second time delay data determination unit is obtainedd,kExpression formula be:
td,k=t0+(d-1)/fs
Wherein, t0Represent time-delay value, fsRepresent sample frequency.
For the present embodiment, the solution unit 106 includes:
First solves module, for the vectorial I it is sparse when, equation group s=MI is asked by compressed sensing algorithm Solution, that is, meetThe I values of condition are the optimal solution of equation group;Wherein, β represents that permission is more Few noise contribution is present;S.t. it is the formal notation for representing logical relation;
Second solves module, for the vectorial I it is not sparse when, sparse transformation is carried out to vectorial I;Calculated by compressed sensing Method is solved to equation group s=MI, that is, meetThe I values of condition be equation group most Excellent solution;Wherein, Ψ represents sparse transformation matrix, and β represents that the how many noise contributions of permission are present;S.t. it is the public affairs for representing logical relation Formula symbol.
For the present embodiment, ripe compressed sensing algorithm includes but is not limited to matching pursuit algorithm (matching Pursuitmethod), Bregman algorithms, operator/variable splitting algorithm (operator/variable splitting), Fixing point continuation algorithm (Fixed-point continuation), L1 norm magics algorithm (L1-magic), Newton tangential method Deng.
Preferably, the ultrasound imaging unit 107 includes:
Conversion module, for vectorial I to be transformed into image array Φ;Wherein, described image matrix Φ is a NXRow Nz The matrix of row;NXThe number of x directions epigraph pixel in three-dimensional system of coordinate is represented, Nz represents the upper figure in z directions in three-dimensional system of coordinate As the number of pixel, N=Nx×Nz
Processing module, for the matrix Φ treatment, obtaining the ultrasonoscopy wanted;Wherein, the side for the treatment of Method includes:Take signal envelope, log-compressed, adjustment image display dynamic range and carry out digital scan conversion.
Have above-mentioned example method describe understand, the technical program on the one hand can realize superelevation frame frequency it is quick ultrasound into Picture, on the other hand ensure that image quality higher, while the hardware computation platform for only needing to reduced levels can be achieved with, be easy to Realize that industry is converted.
Although it should be noted that being referred to supersonic imaging device in above-detailed for a kind of appliance computer software generation The device that code is realized, some units or module that the device includes, but this division is only not enforceable.It is actual On, according to the embodiment of the present invention, the feature and function of above-described two or more devices can be in a system Embody.Conversely, the feature and function of an above-described system can be further divided into being embodied by multiple devices.
Above-described specific embodiment, has been carried out further to the purpose of the present invention, technical scheme and beneficial effect Describe in detail, should be understood that and the foregoing is only specific embodiment of the invention, be not intended to limit the present invention Protection domain, all any modification, equivalent substitution and improvements within the spirit and principles in the present invention, done etc. all should include Within protection scope of the present invention.

Claims (18)

1. a kind of ultrasonic imaging method, it is characterised in that the method includes:
Obtain N × K very first time delayed data tn,k;Wherein, the very first time delayed data tn,kIt is ultrasonic signal from super The sound emission moment, by n-th scattering son scattering, return ultrasound transducer array k-th channel position it is total Time delay;N represents the pixel number of the ultrasonoscopy wanted, and K represents array element number in ultrasound transducer array;N tables Show some scattering, scatter sub- n=1,2 ... ..., N;K represents some passage in ultrasound transducer array, k=1, 2 ... ..., K;
Obtain D × K the second time delay data td,k;Wherein, the second time delay data td,kSent out from ultrasound for known Penetrate and start constantly, the elapsed time postpones, and starts to sample ultrasonic echo radiofrequency signal, obtain ultrasonic echo RF digital letter Number, the moment of k-th channel reception to d-th data point of the ultrasonic echo rf digital signal is sent out relative to ultrasonic signal Send the time delay at moment;D represents the sampling number of each passage, and d represents that a channel reception is believed to ultrasonic echo RF digital Number a certain data point, d=1,2 ... ..., D;
By the ultrasonic echo rf digital signal, accordingly matrixing is that length is the vectorial s of D × K;
Using the corresponding second time delay data t of data point d of k-th passage in the vectorial sd,kAnd under same channels Corresponding very first time delayed data tn,kDetermine matrix M;Wherein, the matrix M is sparse matrix;
Equation group is set up according to the vectorial s and the matrix M;Wherein, the equation group is:S=MI;I is sub to represent scattering Scatter intensity distribution length for N vector;
The equation group is solved by compressed sensing algorithm, vectorial I is obtained;
According to the ultrasonoscopy that the vectorial I determines to want.
2. the method for claim 1, it is characterised in that include the step of the determination matrix M:
Data point d to k-th passage sets up the vectorial m that length is N, obtains D × K vector m;Each in the vectorial m Element determines that method is:If the corresponding second time delay data t of the data point d of k-th passaged,kAnd under same channels Corresponding very first time delayed data tn,kMeetThen from n-th ultrasonic echo information of scattering son scattering It is included in k-th data point d of passage, then nth elements are set to 1 in vector m, otherwise, are set to 0;
D × K vector m is configured to the matrix M of D × K row, N row.
3. method as claimed in claim 1 or 2, it is characterised in that the ultrasonic signal is plane of ultrasound ripple signal.
4. method as claimed in claim 3, it is characterised in that the very first time delayed data tn,kExpression formula be:
t n , k = ( z n + z n 2 + ( x n - x k ) 2 ) / c
Wherein, k-th locus coordinate of passage is (xk,0);N-th space of scattering on the ultrasonoscopy wanted Position coordinates is (xn,zn);C represents sound wave spread speed in media as well;X directions are the width of ultrasonoscopy, z directions It is the depth direction of ultrasonoscopy.
5. method as claimed in claim 1 or 2, it is characterised in that the ultrasonic signal is recessed ultrasonic convex surface ripple signal, ultrasound Face ripple signal.
6. method as claimed in claim 1 or 2, it is characterised in that the second time delay data td,kExpression formula be:
td,k=t0+(d-1)/fs
Wherein, t0Represent and prolong since the time the ultrasound emission moment carries out sampling instant to ultrasonic echo radiofrequency signal It is worth late, fsRepresent sample frequency.
7. method as claimed in claim 1 or 2, it is characterised in that described to be entered by compressed sensing algorithm to the equation group The step of row is solved includes:
If vector I is sparse, equation group s=MI is solved by compressed sensing algorithm, that is, met min | | I | | 1 s . t . | | s - MI | | 2 2 ≤ β 2 The I values of condition are the optimal solution of equation group;Wherein, β represents permission how many noise contribution In the presence of;S.t. it is the formal notation for representing logical relation;
Otherwise, sparse transformation is carried out to vectorial I;Equation group s=MI is solved by compressed sensing algorithm, that is, is met min | | ΨI | | 1 s . t . | | s - MI | | 2 2 ≤ β 2 The I values of condition are the optimal solution of equation group;Wherein, Ψ represents sparse transformation matrix, β Representing allows how many noise contributions to exist;S.t. it is the formal notation for representing logical relation.
8. method as claimed in claim 7, it is characterised in that the compressed sensing algorithm is that matching pursuit algorithm, Bregman are calculated Method, operator/variable splitting algorithm, fixing point continuation algorithm, L1 norm magics algorithm, Newton tangential method.
9. method as claimed in claim 1 or 2, it is characterised in that include the step of the ultrasonoscopy that the determination is wanted:
Vectorial I is transformed to image array Φ;Wherein, described image matrix Φ is a NxRow NzCapable matrix;NxRepresent three-dimensional The number of x directions epigraph pixel, N in coordinate systemzRepresent the number of z directions epigraph pixel in three-dimensional system of coordinate, N=Nx× Nz
To the matrix Φ treatment, the ultrasonoscopy wanted is obtained;Wherein, the method for the treatment of includes:Take signal envelope, Log-compressed, adjustment and carry out digital scan conversion at image display dynamic range.
10. a kind of supersonic imaging device, it is characterised in that the device includes:
Very first time delayed data determining unit, for obtaining N × K very first time delayed data tn,k;Wherein, described first Time delay data tn,kIt is ultrasonic signal since the ultrasound emission moment, by n-th scattering of scattering, returns ultrasound Total time delay of k-th channel position of transducer array;N represents the pixel number of the ultrasonoscopy wanted, and K is represented Array element number in ultrasound transducer array;N represents some scattering, scatters sub- n=1,2 ... ..., N;K represents ultrasonic transduction Some passage, k=1,2 ... ..., K in device array;
Second time delay data determination unit, for obtaining D × K the second time delay data td,k;Wherein, described second Time delay data td,kFor known since the ultrasound emission moment, the elapsed time postpones, and starts to enter ultrasonic echo radiofrequency signal Row sampling, obtains ultrasonic echo rf digital signal, d of k-th channel reception to the ultrasonic echo rf digital signal Time delay of the individual data point relative to ultrasonic signal delivery time;D represents the sampling number of each passage, and d represents a passage Receive a certain data point of ultrasonic echo rf digital signal, d=1,2 ... ..., D;
Converter unit, for accordingly matrixing to be that length is the vectorial s of D × K by the ultrasonic echo rf digital signal;
Matrix determining unit, for the corresponding second time delay data of data point d using k-th passage in the vectorial s td,kAnd corresponding very first time delayed data t under same channelsn,kDetermine matrix M;Wherein, the matrix M is sparse matrix;
Model sets up unit, for setting up equation group according to the vectorial s and the matrix M;Wherein, the equation group is:S= MI;I represents that the scatter intensity distribution of scattering, length are the vector of N;
Unit is solved, for being solved by compressed sensing algorithm to the equation group, vectorial I is obtained;
Ultrasound imaging unit, for the ultrasonoscopy for determining to want according to the vectorial I.
11. devices as claimed in claim 10, it is characterised in that the matrix determining unit includes:
Vector sets up module, and the vectorial m that length is N is set up for the data point d to k-th passage, obtains D × K vector m; Each element in the vectorial m determines that method is:If the corresponding second time delay data of the data point d of k-th passage td,kAnd corresponding very first time delayed data t under same channelsn,kMeetThen dissipated from n-th scattering The ultrasonic echo information penetrated is included in k-th data point d of passage, then nth elements are set to 1 in vector m, otherwise, are set to 0;
Constructing module, the matrix M for D × K vector m to be configured to D × K row, N row.
12. device as described in claim 10 or 11, it is characterised in that the ultrasonic signal of supersonic imaging device treatment is Plane of ultrasound ripple signal.
13. devices as claimed in claim 12, it is characterised in that the very first time delayed data determining unit obtain the One time delayed data tn,kExpression formula be:
t n , k = ( z n + z n 2 + ( x n - x k ) 2 ) / c
Wherein, k-th coordinate of passage is (xk,0);The coordinate of n-th scattering of the ultrasonoscopy wanted is (xn,zn); C represents sound wave spread speed in media as well.
14. device as described in claim 10 or 11, it is characterised in that the ultrasonic signal of supersonic imaging device treatment is Ultrasonic convex surface ripple signal, ultrasonic concave surface ripple signal.
15. device as described in claim 10 or 11, it is characterised in that the second time delay data determination unit is obtained The second time delay data td,kExpression formula be:
td,k=t0+(d-1)/fs
Wherein, t0Represent time-delay value, fsRepresent sample frequency.
16. device as described in claim 10 or 11, it is characterised in that the solution unit includes:
First solves module, for the vectorial I it is sparse when, equation group s=MI is solved by compressed sensing algorithm, i.e., Meet min | | I | | 1 s . t . | | s - MI | | 2 2 ≤ β 2 The I values of condition are the optimal solution of equation group;Wherein, β represents permission how many noise Composition is present;S.t. it is the formal notation for representing logical relation;
Second solves module, for the vectorial I it is not sparse when, sparse transformation is carried out to vectorial I;By compressed sensing algorithm pair Equation group s=MI is solved, that is, meet min | | ΨI | | 1 s . t . | | s - MI | | 2 2 ≤ β 2 The I values of condition are optimal for equation group Solution;Wherein, Ψ represents sparse transformation matrix, and β represents that the how many noise contributions of permission are present;S.t. it is the formula for representing logical relation Symbol.
17. devices as claimed in claim 16, it is characterised in that the compressed sensing algorithm that the solution unit is used is matching Back tracking method, Bregman algorithms, operator/variable splitting algorithm, fixing point continuation algorithm, L1 norm magics algorithm, newton decline Method.
18. device as described in claim 10 or 11, it is characterised in that the ultrasound imaging unit includes:
Conversion module, for vectorial I to be transformed into image array Φ;Wherein, described image matrix Φ is a NxThe square of row Nz row Battle array;NXThe number of x directions epigraph pixel in three-dimensional system of coordinate is represented, Nz represents z directions epigraph pixel in three-dimensional system of coordinate Number, N=Nx×Nz
Processing module, for the matrix Φ treatment, obtaining the ultrasonoscopy wanted;Wherein, the method bag for the treatment of Include:Take signal envelope, log-compressed, adjustment image display dynamic range and carry out digital scan conversion.
CN201510158465.4A 2015-04-03 2015-04-03 A kind of ultrasonic imaging method and device Active CN104739448B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510158465.4A CN104739448B (en) 2015-04-03 2015-04-03 A kind of ultrasonic imaging method and device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510158465.4A CN104739448B (en) 2015-04-03 2015-04-03 A kind of ultrasonic imaging method and device

Publications (2)

Publication Number Publication Date
CN104739448A CN104739448A (en) 2015-07-01
CN104739448B true CN104739448B (en) 2017-07-07

Family

ID=53580105

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201510158465.4A Active CN104739448B (en) 2015-04-03 2015-04-03 A kind of ultrasonic imaging method and device

Country Status (1)

Country Link
CN (1) CN104739448B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106691499B (en) * 2015-07-17 2020-09-18 安克生医股份有限公司 Method for analyzing an ultrasonic echo signal using scatterer distribution statistics
WO2017035838A1 (en) * 2015-09-06 2017-03-09 深圳迈瑞生物医疗电子股份有限公司 Ultrasound gray-scale imaging system and method
CN105748103B (en) * 2016-04-22 2019-08-23 深圳先进技术研究院 Delayed excitation ultrasonic imaging method and device
CN106680825B (en) * 2016-12-05 2019-06-04 中国科学院声学研究所 A kind of acoustic array imaging system and method
CN106780329B (en) * 2016-12-07 2019-08-30 华中科技大学 A kind of plane of ultrasound wave imaging method based on the transformation of anti-perspective plane
CN106997045B (en) * 2017-03-06 2020-08-28 中国科学院深圳先进技术研究院 Ultrasonic imaging method based on ultrasonic system point spread function measurement and compressed sensing
CN106940883B (en) * 2017-03-06 2020-10-16 中国科学院深圳先进技术研究院 Ultrasonic imaging method based on point spread function simulation and compressed sensing of ultrasonic system
WO2019095376A1 (en) * 2017-11-20 2019-05-23 深圳迈瑞生物医疗电子股份有限公司 Ultrasound contrast imaging method and ultrasound imaging system
CN108445083A (en) * 2018-02-11 2018-08-24 天津大学 A kind of phased array supersonic image reconstruction optimization method based on frequency domain compressed sensing
CN109758091B (en) * 2018-12-03 2020-12-01 深圳先进技术研究院 Ultrasonic imaging method and device
CN110244305A (en) * 2019-07-10 2019-09-17 南京信息工程大学 A kind of emulation mode of Underwater Target Signal scattering
CN111580112B (en) * 2020-06-11 2023-02-14 南京信息工程大学 Underwater sonar sensor array imaging method based on plane waves

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102920478A (en) * 2012-11-22 2013-02-13 山东大学 Synthetic-focusing imaging method of portable type-B ultrasonic equipment
EP2660618A1 (en) * 2012-05-04 2013-11-06 Esaote S.p.A. Biomedical image reconstruction method

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7584062B1 (en) * 2008-06-20 2009-09-01 The Boeing Company Sub-wavelength ultrasound characterization of composite material
CN102058416B (en) * 2010-12-14 2012-09-19 哈尔滨工业大学 Microwave thermoacoustic imaging device and method based on compressive sensing

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2660618A1 (en) * 2012-05-04 2013-11-06 Esaote S.p.A. Biomedical image reconstruction method
CN102920478A (en) * 2012-11-22 2013-02-13 山东大学 Synthetic-focusing imaging method of portable type-B ultrasonic equipment

Also Published As

Publication number Publication date
CN104739448A (en) 2015-07-01

Similar Documents

Publication Publication Date Title
CN104739448B (en) A kind of ultrasonic imaging method and device
US11464492B2 (en) Point source transmission and speed-of-sound correction using multi-aperture ultrasound imaging
KR101651830B1 (en) Feedback in medical ultrasound imaging for high intensity focused ultrasound
JP5627890B2 (en) Dual path processing for optimal speckle tracking
CN111134719B (en) Active and passive ultrasonic composite imaging method and system for phase-change nano liquid drops through focused ultrasonic irradiation
Tasinkevych et al. Modified synthetic transmit aperture algorithm for ultrasound imaging
Zhang et al. Extension of Fourier-based techniques for ultrafast imaging in ultrasound with diverging waves
Bandaru et al. Delay and standard deviation beamforming to enhance specular reflections in ultrasound imaging
US20140180111A1 (en) Remote controlled telemedical ultrasonic diagnostic device
Foroozan et al. Microbubble localization for three-dimensional superresolution ultrasound imaging using curve fitting and deconvolution methods
JP4320392B2 (en) Method and apparatus for high distortion rate removal filtering
CN106940883B (en) Ultrasonic imaging method based on point spread function simulation and compressed sensing of ultrasonic system
Hemmsen et al. Tissue harmonic synthetic aperture ultrasound imaging
Medina-Valdés et al. Multi-modal ultrasound imaging for breast cancer detection
Mirzaei et al. Virtual source synthetic aperture for accurate lateral displacement estimation in ultrasound elastography
CN115721336A (en) Ultrasonic plane wave imaging method, device and equipment
CN114519752B (en) High-resolution rapid-calculation passive ultrasonic imaging method and system
Heller et al. Deep learning-based speed-of-sound reconstruction for single-sided pulse-echo ultrasound using a coherency measure as input feature
CN107204021A (en) Ultrasonic imaging method based on Gaussian function sonde response model and compressed sensing
Racedo et al. Evaluation of reconstruction parameters for 2-D comb-push ultrasound shear wave elastography
Wang et al. An easily-achieved time-domain beamformer for ultrafast ultrasound imaging based on compressive sensing
Ahmed et al. Parallel receive beamforming improves the performance of focused transmit-based single-track location shear wave elastography
Barber et al. Compressibility and density weighting for ultrasound scattering tomography
Boulos et al. Passive cavitation imaging using different advanced beamforming methods
CN106997045B (en) Ultrasonic imaging method based on ultrasonic system point spread function measurement and compressed sensing

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant