CN104721949A - Intestinal nutrition close-loop intelligent infusion system based on small intestine intestinal cavity pressure - Google Patents
Intestinal nutrition close-loop intelligent infusion system based on small intestine intestinal cavity pressure Download PDFInfo
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- CN104721949A CN104721949A CN201510167310.7A CN201510167310A CN104721949A CN 104721949 A CN104721949 A CN 104721949A CN 201510167310 A CN201510167310 A CN 201510167310A CN 104721949 A CN104721949 A CN 104721949A
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- 230000000968 intestinal effect Effects 0.000 title claims abstract description 71
- 235000016709 nutrition Nutrition 0.000 title claims abstract description 65
- 238000001802 infusion Methods 0.000 title claims abstract description 58
- 230000035764 nutrition Effects 0.000 title claims abstract description 48
- 210000000813 small intestine Anatomy 0.000 title abstract description 5
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- 235000021476 total parenteral nutrition Nutrition 0.000 description 4
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Abstract
The invention discloses an intestinal nutrition close-loop intelligent infusion system based on small intestine intestinal cavity pressure. The intestinal nutrition close-loop intelligent infusion system based on the small intestine intestinal cavity pressure comprises an intestinal nutrient solution infusion tube, an intestinal cavity pressure measurement tube, a nutrient solution infusion pump and an intestinal cavity pressure signal processing system, and wherein a pressure sensor is arranged on the lower end of the intestinal cavity pressure measurement tube; the nutrient solution infusion pump infuses an intestinal nutrient solution for the inside of an intestine through the upper port of the intestinal nutrient solution infusion tube; the intestinal cavity pressure signal processing system performs processing on an intestinal cavity pressure signal collected by the pressure sensor and transmits processed results to a flow control module, and the flow control module self-adaptively controls the nutrient solution infusion pump according to the processed results and the actual flow value of the nutrient solution fed back by a flow feedback module. According to the intestinal nutrition close-loop intelligent infusion system based on the small intestine intestinal cavity pressure, the intestinal tract complications can be reduced, the accompanying work load is reduced, medical expenses are reduced, the current situation of high cost of getting medical treatment is relieved, therefore, the intestinal nutrition can be widely applied to clinical practice more effectively, and the technological base is established for implementing the intestinal nutrition in communities and homes.
Description
Technical field
The invention belongs to medical instruments field, specifically a kind of intelligence of the enteral nutrition closed loop based on small intestinal enteric cavity pressure infusion system.
Background technology
The homergy of human body and good nutritional status are the important guarantees safeguarding vital movement.Any metabolism disorder or malnutrition all can affect the function of tissue, organ, worsen further and can make organ failure.The nutritional status of body and morbidity and mortality rate are closely-related.All can there is malnutrition in various degree in many critical illness, corrected if do not adopted vigorous measures, and is often difficult to give treatment to successfully.On basis organism metabolism being had to enough understanding, the foundation of effective import pathway, and various production in succession and the application meeting the little nutritional preparation of physiology, side reaction, make professional Medical Degree treatment in modern age obtain very outstanding effect, save the life of many critical patients.
Total parenteral nutrition (total parenteral nutrition, TPN) is the nutrition supporting therapy developed rapidly in the later stage sixties 20th century, once in wide clinical application.But along with progressively going deep into of studying nutritional support theory and practice, people recognize that parenteral nutrition mainly exists three class complication, comprise: (1) technical complication: as the damage of pneumothorax, blood vessel injury, nerve or thoracic duct, the most serious has air embolism, once it is serious that consequence occurs, even cause death; (2) metabolic complication: the electrolyte disturbance, trace element deficiency, the essential amino acids shortage that cause as supplementary deficiency, the hypoglycemia that carbohydrate metabolism disturbance causes or hyperglycemia, liver function injury, also can cause gallbladder inner bag mud and calculus, the rising of cholestasis regulating liver-QI zymogram, intestinal barrier function to go down in addition; (3) infection complication: as conduit sepsis.
Enteral nutrition (enteral nutrition, EN) is not only more reduced expenses than TPN, and more meets physiological status, is considered to the important measures recovering intestinal blood flow, improve intestinal function.Along with the development of enteral nutrition, in nutritional support process, metabolic complication greatly reduces.But in the implementation process of enteral nutrition, patient often there will be the intestinal tract complications such as abdominal distention, stomachache, diarrhoea.The generation of intestinal tract complication and the toleration of small intestinal to enteral nutrition closely related.Therefore further investigation and improve patient to the toleration of enteral nutrition to guidance clinical effectively implement enteral nutrition have important value.
Small intestinal is not only subject to the impact of enteral nutrition scheme, Small Intestine and paathogenic factor on the toleration of enteral nutrition, also by the impact of the factors such as nutrient composition, osmotic pressure, input time, speed, temperature, concentration and nutritive canal implantation mode, and the impact of these factors is often embodied a concentrated reflection of in the change of intestinal cavity pressure.
At present, domestic and international present Research and development trend as follows:
Nutritional support is considered to one of greatest achievement of 20th century medical circle, but is difficult to carry out without effective approach and preparation with cause in the 1950's as the enteral nutrition of nutritional support important component part.Nineteen fifty-seven be spaceman exploitation enteral nutrition preparation because normal growth, the reproduction of rat can be maintained, be applied to human body in nineteen sixty-five, enteral nutrition is progressively carried out clinical since then.
To 20th century the mid-80 along with being familiar with again intestinal function, especially the establishment of the new theory such as " intestinal mucosal barrier ", " in intestinal bacterial translocation " and " intestinal is a center organ of stress ", new ideas, the application and research of EN support is increasing.Enteral nutrition contributes to the integrity maintaining intestinal mucosa cells structure and fuction, support intestinal mucosal barrier, reduce the generation of enterogenic infection, and be considered to the important method improving cancer patient nutriture and quality of life, so the ratio of external clinical practice enteral nutrition is increased to 80% by original 20%, domesticly also to increase sharply.
But in concrete clinical implementation process, enteral nutrition not can be easily accepted by the patient.Too early, implement enteral nutrition too quickly and occur severe complication sometimes, such as bowel necrosis.At present enteral nutrition toleration is evaluated to the clinical manifestation of Main Basis patient, as gastrointestinal reactions such as abdominal distention, stomachache and diarrhoea, and lack the evaluation index of objectivity.
Because the intrinsic factor affecting little gut tolerance during enteral nutrition are intestinal motility and absorption function two aspects, therefore the comprehensive objective evaluation index of objective indicator as little gut tolerance of searching above-mentioned two aspects of concentrated expression can be imagined, thus reach requirement that is accurate, comprehensive, objective evaluation.Chinese scholars is once using the research method of the mensuration of enteric cavity pressure as intestinal movement function, current research display: for the small intestinal accepting enteral nutrition, the change of enteric cavity pressure is the synthesis result of intestinal motility and absorption function change, is also disconnected and occur the pathogenesis basis of the intestinal tract complications such as abdominal distention, stomachache and diarrhoea.Therefore, small intestinal intestinal cavity pressure mensuration can concentrated expression intestinal motility and absorption function change overall condition.
Generally, when jejunal nutrition, any method of intubation is all a certain position being fixed on small intestinal, and every section of intestinal motility all shrinks-relaxes and hockets, namely each position enteral pressure is constantly change, so desirable intestinal nutrient solution input method automatically can speed input, input of slowing down when enteral voltage rise height when enteral pressure lowers, even minibreak, makes the change of enteral pressure play the effect intelligently adjusting infusion.This infusion methods has also taken into account the daily cycle property change of gastrointestinal physiological function, farthest can improve the toleration of small intestinal to enteral nutrition.
Summary of the invention
The object of the present invention is to provide a kind of enteral nutrition closed loop based on small intestinal enteric cavity pressure intelligence infusion system, to reduce intestinal tract complication, lower workload of accompanying and attending to, reduce medical expense.
For achieving the above object, the invention provides following technical scheme:
A kind of intelligence of the enteral nutrition closed loop based on small intestinal enteric cavity pressure infusion system, comprise intestinal nutrient solution infusion tube, enteric cavity piezometry pipe, nutritional solution infusion pump and enteric cavity pressure signal processing system, described enteric cavity piezometry pipe is positioned at outside intestinal nutrient solution infusion tube, and is connected with the sidewall of intestinal nutrient solution infusion tube; The lower port of described enteric cavity piezometry pipe is provided with pressure transducer, and pressure transducer is positioned at 3.5-4.5cm place above intestinal nutrient solution infusion tube lower port; Intestinal nutrient solution infusion tube sidewall between the lower port and the lower port of enteric cavity piezometry pipe of intestinal nutrient solution infusion tube is evenly staggeredly distributed with 1-10 trophopore; Described nutritional solution infusion pump is enteral feeding intestinal nutrient solution by intestinal nutrient solution infusion tube upper port; The enteric cavity pressure signal of pressure transducer collection processes by described enteric cavity pressure signal processing system, and result is passed to flow-control module, described flow-control module is according to the control nutritional solution infusion pump to the result of enteric cavity pressure and the nutritional solution actual flow size adaptation of flow feedback module feedback.
As the further scheme of the present invention: described enteric cavity pressure signal processing system comprises I-V change-over circuit, pre-amplification circuit, active band-pass filter, second amplifying circuit, analog-to-digital conversion module, iir digital filter, microcontroller and state indicator module; Described I-V change-over circuit is used for the current signal of pressure transducer to be converted to voltage signal; Pre-amplification circuit is used for voltage signal to amplify; Active band-pass filter is used for filtering and amplifies noise and Hz noise in rear voltage signal; Second amplifying circuit is used for again amplifying voltage signal; Analog-to-digital conversion module is used for voltage signal to be converted to digital signal; Iir digital filter is used for carrying out filtering to digital signal; Digital signal for the digital signal after accepting filter, and is converted into real pressure signal by microcontroller, then controls flow-control module according to pressure signal; Described state indicator module is for showing the execution result of flow-control module.
As the further scheme of the present invention: described pressure sensor design has isolation protective circuit.
As the further scheme of the present invention: described pressure transducer is positioned at 4cm place above intestinal nutrient solution infusion tube lower port.
As the further scheme of the present invention: described trophopore is provided with 5-6.
Compared with prior art, the invention has the beneficial effects as follows: this system can reduce intestinal tract complication, lower workload of accompanying and attending to, reduce medical expense, alleviate the present situation of " high cost of getting medical treatment ", making enteral nutrition can more effectively extensive use clinically, also establishing technical foundation for implementing enteral nutrition in community and family.
Accompanying drawing explanation
Fig. 1 is the structural representation for the novel enteral nutrition pipe of infusion nutrient solution and conduction enteric cavity pressure in the present invention.
Fig. 2 is the theory diagram of the enteral nutrition closed loop intelligence infusion system based on small intestinal enteric cavity pressure.
Detailed description of the invention
Be described in more detail below in conjunction with the technical scheme of detailed description of the invention to this patent.
Refer to Fig. 1 and Fig. 2, a kind of intelligence of the enteral nutrition closed loop based on small intestinal enteric cavity pressure infusion system, comprise intestinal nutrient solution infusion tube 1, enteric cavity piezometry pipe 2, nutritional solution infusion pump and enteric cavity pressure signal processing system, described enteric cavity piezometry pipe 2 is positioned at outside intestinal nutrient solution infusion tube 1, and is connected with the sidewall of intestinal nutrient solution infusion tube 1; The lower port of described enteric cavity piezometry pipe 2 is provided with pressure transducer 11, and pressure transducer 11 is positioned at 3.5-4.5cm place above intestinal nutrient solution infusion tube 1 lower port, is preferably 4cm; Intestinal nutrient solution infusion tube 1 sidewall between the lower port and the lower port of enteric cavity piezometry pipe 2 of intestinal nutrient solution infusion tube 1 is evenly staggeredly distributed with 1-10 trophopore 21; Described nutritional solution infusion pump is enteral feeding intestinal nutrient solution by intestinal nutrient solution infusion tube 1 upper port; The enteric cavity pressure signal that pressure transducer 11 gathers by described enteric cavity pressure signal processing system processes, and result is passed to flow-control module, described flow-control module is according to the control nutritional solution infusion pump to the result of enteric cavity pressure and the nutritional solution actual flow size adaptation of flow feedback module feedback.
In the present invention, described enteric cavity pressure signal processing system comprises I-V change-over circuit, pre-amplification circuit, active band-pass filter, second amplifying circuit, analog-to-digital conversion module, iir digital filter, microcontroller and state indicator module; Described I-V change-over circuit is used for the current signal of pressure transducer 11 to be converted to voltage signal; Pre-amplification circuit is used for voltage signal to amplify; Active band-pass filter is used for filtering and amplifies noise and Hz noise in rear voltage signal; Second amplifying circuit is used for again amplifying voltage signal; Analog-to-digital conversion module is used for voltage signal to be converted to digital signal; Iir digital filter is used for carrying out filtering to digital signal; Digital signal for the digital signal after accepting filter, and is converted into real pressure signal by microcontroller, then controls flow-control module according to pressure signal; Described state indicator module is for showing the execution result of flow-control module.
In the present invention, because charged pressure transducer needs to contact human body, and be inserted into little enteral to measure, so described pressure sensor design has isolation protective circuit, so as to avoid an accident.
The present invention is first a kind of for infusion nutrient solution and the novel enteral nutrition pipe conducting enteric cavity pressure by development, for collecting, analyze small intestinal intestinal cavity pressure delta data, Real Time Observation also determines the intrinsic pressure scope of enteric cavity being applicable to implementing enteral nutrition: and then develop can according to the closed loop intelligence infusion signal processing system of enteral pressure change enteral nutrition, namely based on the enteral nutrition closed loop intelligence infusion system of small intestinal enteric cavity pressure, this system can reduce intestinal tract complication, lower workload of accompanying and attending to, reduce medical expense, alleviate the present situation of " high cost of getting medical treatment ", make enteral nutrition can more effectively extensive use clinically, electricity establishes technical foundation for implementing enteral nutrition in community and family.
Above the better embodiment of this patent is explained in detail, but this patent is not limited to above-mentioned embodiment, in the ken that one skilled in the relevant art possesses, can also makes a variety of changes under the prerequisite not departing from this patent aim.
Claims (5)
1. the intelligence of the enteral nutrition closed loop based on a small intestinal enteric cavity pressure infusion system, comprise intestinal nutrient solution infusion tube, enteric cavity piezometry pipe, nutritional solution infusion pump and enteric cavity pressure signal processing system, it is characterized in that, described enteric cavity piezometry pipe is positioned at outside intestinal nutrient solution infusion tube, and is connected with the sidewall of intestinal nutrient solution infusion tube; The lower port of described enteric cavity piezometry pipe is provided with pressure transducer, and pressure transducer is positioned at 3.5-4.5cm place above intestinal nutrient solution infusion tube lower port; Intestinal nutrient solution infusion tube sidewall between the lower port and the lower port of enteric cavity piezometry pipe of intestinal nutrient solution infusion tube is evenly staggeredly distributed with 1-10 trophopore; Described nutritional solution infusion pump is enteral feeding intestinal nutrient solution by intestinal nutrient solution infusion tube upper port; The enteric cavity pressure signal of pressure transducer collection processes by described enteric cavity pressure signal processing system, and result is passed to flow-control module, described flow-control module is according to the control nutritional solution infusion pump to the result of enteric cavity pressure and the nutritional solution actual flow size adaptation of flow feedback module feedback.
2. the intelligence of the enteral nutrition closed loop based on small intestinal enteric cavity pressure infusion system according to claim 1, it is characterized in that, described enteric cavity pressure signal processing system comprises I-V change-over circuit, pre-amplification circuit, active band-pass filter, second amplifying circuit, analog-to-digital conversion module, iir digital filter, microcontroller and state indicator module; Described I-V change-over circuit is used for the current signal of pressure transducer to be converted to voltage signal; Pre-amplification circuit is used for voltage signal to amplify; Active band-pass filter is used for filtering and amplifies noise and Hz noise in rear voltage signal; Second amplifying circuit is used for again amplifying voltage signal; Analog-to-digital conversion module is used for voltage signal to be converted to digital signal; HR digital filter is used for carrying out filtering to digital signal; Digital signal for the digital signal after accepting filter, and is converted into real pressure signal by microcontroller, then according to the empty flow-control module processed of pressure signal; Described state indicator module is for showing the execution result of flow-control module.
3. the intelligence of the enteral nutrition closed loop based on small intestinal enteric cavity pressure infusion system according to claim 1 and 2, it is characterized in that, described pressure sensor design has isolation protective circuit.
4. the intelligence of the enteral nutrition closed loop based on small intestinal enteric cavity pressure infusion system according to claim 1 and 2, it is characterized in that, described pressure transducer is positioned at 4cm place above intestinal nutrient solution infusion tube lower port.
5. the intelligence of the enteral nutrition closed loop based on small intestinal enteric cavity pressure infusion system according to claim 1 and 2, it is characterized in that, described trophopore is provided with 5-6.
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CN112603834A (en) * | 2020-12-18 | 2021-04-06 | 南通市第一人民医院 | Control system and method for enteral nutrition input of patient |
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US20080097179A1 (en) * | 2006-07-03 | 2008-04-24 | Russo Susan H | Feeding tube system with reflux fluid sensing |
CN202876058U (en) * | 2012-09-29 | 2013-04-17 | 边俊杰 | Trio-cavity stomach tube with oxygen uptake cavity |
CN203107729U (en) * | 2013-02-05 | 2013-08-07 | 王剑 | Enteral nutrition pipe with enteral pressure monitoring function |
CN204563247U (en) * | 2015-04-10 | 2015-08-19 | 嘉兴学院 | Novel enteral nutrition pipe and enteral nutrition closed loop intelligence infusion system |
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Publication number | Priority date | Publication date | Assignee | Title |
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US20080097179A1 (en) * | 2006-07-03 | 2008-04-24 | Russo Susan H | Feeding tube system with reflux fluid sensing |
CN202876058U (en) * | 2012-09-29 | 2013-04-17 | 边俊杰 | Trio-cavity stomach tube with oxygen uptake cavity |
CN203107729U (en) * | 2013-02-05 | 2013-08-07 | 王剑 | Enteral nutrition pipe with enteral pressure monitoring function |
CN204563247U (en) * | 2015-04-10 | 2015-08-19 | 嘉兴学院 | Novel enteral nutrition pipe and enteral nutrition closed loop intelligence infusion system |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN112603834A (en) * | 2020-12-18 | 2021-04-06 | 南通市第一人民医院 | Control system and method for enteral nutrition input of patient |
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