CN104688209A - Invasive blood pressure detecting and analyzing method and system - Google Patents

Invasive blood pressure detecting and analyzing method and system Download PDF

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Publication number
CN104688209A
CN104688209A CN201310646565.2A CN201310646565A CN104688209A CN 104688209 A CN104688209 A CN 104688209A CN 201310646565 A CN201310646565 A CN 201310646565A CN 104688209 A CN104688209 A CN 104688209A
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China
Prior art keywords
blood pressure
invasive blood
real
aorta
pressure signal
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CN201310646565.2A
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Chinese (zh)
Inventor
聂金柱
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Lepu Medical Technology Beijing Co Ltd
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Lepu Medical Technology Beijing Co Ltd
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Priority to CN201310646565.2A priority Critical patent/CN104688209A/en
Publication of CN104688209A publication Critical patent/CN104688209A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021Measuring pressure in heart or blood vessels
    • A61B5/0215Measuring pressure in heart or blood vessels by means inserted into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10Location thereof with respect to the patient's body
    • A61M60/122Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
    • A61M60/126Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
    • A61M60/135Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel inside a blood vessel, e.g. using grafting

Abstract

The invention provides an invasive blood pressure detecting and analyzing method and system. The invasive blood pressure detecting and analyzing method includes the steps of conducting real-time collecting on the invasive blood pressure; conducting real-time peak value and heavy pulse point detection on collected invasive blood pressure signals, and estimating the time when a peak value and a heavy pulse point of a next invasive blood pressure signal occur; and according to the time when the peak value and the heavy pulse point of the next invasive blood pressure signal occur, controlling air inflation and deflation operation of an aorta saccule. By means of the invasive blood pressure detecting and analyzing method and system, real-time collecting on the invasive blood pressure can be carried out, real-time peak value and heavy pulse point detection is carried out, and the air inflation and deflation operation of the aorta saccule is carried out according to the forecasted time when the peak value and the heavy pulse point of the next invasive blood pressure signal occur. By means of the invasive blood pressure detecting and analyzing method and system, real-time control over air inflation and deflation of the aorta saccule in an of the aorta saccule back-pulse method is achieved through real-time detection on the invasive blood pressure.

Description

A kind of invasive blood pressure determination and analysis method and system
Technical field
The present invention relates to interventional therapy field, particularly relate to a kind of invasive blood pressure determination and analysis method and system.
Background technology
Intra aortic balloon counterpulsation (Intra-Aortic Balloon Pump, IABP) is one of mechanicalness assist circulation method, by physical action, improves diastolic pressure in aorta, increases coronary artery blood supply and improve myocardial function.This method has been widely used in rescue and the treatment of the critical patients such as cardiac insufficiency.
Intra aortic balloon counterpulsation is made up of the cylindrical aorta after balloon being fixed on conduit, aorta after balloon is placed in thoracic aorta position.Catheter proximal end is positioned at left subclavian artery tip, and far-end is positioned at renal artery.The aorta after balloon inflation when diastole, aorta after balloon venting during heart contraction, produces dual haemodynamic effect thus: the inflation of diastole aorta after balloon makes blood flow forward, improves the perfusion of diastolic pressure and arteria coronaria; Aorta after balloon was exitted and is reduced systolic pressure (cardiac afterload) thus improve left ventricular ejection before heart contraction.Can in each cardiac cycle by aorta after balloon inflation/deflation once (1:1 pattern) by control station, also can in every two cardiac cycles by aorta after balloon inflation/deflation once (1:2 pattern), in every three cardiac cycles, inflation/deflation is once (1:3 pattern).Control station can adjust the size of aorta after balloon according to the number of the gas flow entering aorta after balloon.
But in the prior art, said process is all generally realize in vitro, lacks the real-time monitoring to human body physical sign and Real-time Feedback, cannot realize the real-time control to aorta after balloon inflation/deflation.
Summary of the invention
(1) technical problem that will solve
The invention provides kind of an invasive blood pressure determination and analysis method and system, to solve the technical problem cannot carrying out control in real time in prior art to aorta after balloon inflation/deflation.
(2) technical scheme
For solving the problems of the technologies described above, the invention provides a kind of invasive blood pressure determination and analysis method, comprising:
Real-time Collection is carried out to invasive blood pressure;
Peak values in real time and heavily rich some detection are carried out to the invasive blood pressure signal collected, and estimates the peak value of invasive blood pressure signal next time and a heavily rich moment occurred;
According to the moment that peak value and the heavily rich point of the described signal of invasive blood pressure next time occur, control the inflation/deflation operation of aorta after balloon.
Further,
Describedly Real-time Collection is carried out to invasive blood pressure comprise: the blood pressure being measured femoral artery by puncture, measure the arterial pressure gathering femoral artery in real time;
Described Real-time Collection is carried out to invasive blood pressure after, and also comprised before the described invasive blood pressure signal to collecting carries out peak values in real time and heavily rich point detects: filter amplifying processing is carried out to the circuit noise of the invasive blood pressure signal collected and needle position misalignment, and the invasive blood pressure analogue signal after process is carried out analog digital conversion;
The described invasive blood pressure signal to collecting carries out peak values in real time and the detection of heavily rich point comprises: by wavelet transformation, detects the peak values in real time of the invasive blood pressure signal collected and heavily rich point;
The moment of the described peak value and heavily rich some appearance of estimating invasive blood pressure signal next time comprises: utilize history invasive blood pressure Signal estimation to draw the running status of system, in conjunction with peak value and the heavily rich point of the invasive blood pressure signal of Real-time Collection, estimate the peak value of invasive blood pressure signal next time and the moment of heavily rich some appearance.
Further, describedly pass through wavelet transformation, the peak values in real time and the heavily rich point that detect the invasive blood pressure signal collected also comprise: according to the characteristic of wavelet basis function and the feature of described invasive blood pressure signal, determine type and the Lifting Wavelet Decomposition order of wavelet basis function.
Further, in moment of occurring of the peak value of invasive blood pressure signal and heavily rich point next time described in described basis, the inflation/deflation operation controlling aorta after balloon comprises:
In the moment that upper once invasive blood pressure signal peak occurs, aorta after balloon is inflated, in the moment that the heavily rich point of upper once invasive blood pressure signal occurs, aorta after balloon is exitted;
Real-Time Monitoring is carried out to the air pressure of blood pressure and aorta after balloon inflation/deflation; The heart change of burst is manually stopped.
Further, described method also comprises: carry out initial setting up by arranging the mode gathered or trigger to inflation/deflation gas circuit.
On the other hand, the present invention also provides a kind of invasive blood pressure determination and analysis system, comprising: invasive blood pressure acquisition system, digital signal processor and air-path control system that order is connected, wherein:
Invasive blood pressure acquisition system, for carrying out Real-time Collection to invasive blood pressure;
Digital signal processor, for carrying out peak values in real time and heavily rich some detection to the invasive blood pressure signal collected, and estimates the peak value of invasive blood pressure signal next time and a heavily rich moment occurred;
Air-path control system, comprises aorta after balloon, for the moment occurred according to peak value and the heavily rich point of the described signal of invasive blood pressure next time, controls the inflation/deflation operation of aorta after balloon.
Further,
Described invasive blood pressure acquisition system comprises: invasive blood pressure sensor system, comprise ductus arteriosus, pressure connection tube, pressure transducer, continuous flushing system and invasive blood pressure sensor, for being measured the blood pressure of femoral artery by puncture, measure the arterial pressure gathering femoral artery in real time;
Described system also comprises: signal processing unit, be connected between described invasive blood pressure acquisition system and described digital signal processor, comprise low-noise operational amplifier, amplifying circuit and 16 analog-digital converters, for carrying out filter amplifying processing to the circuit noise of the invasive blood pressure signal collected and needle position misalignment, and the invasive blood pressure analogue signal after process is carried out analog digital conversion;
Described digital signal processor comprises: wavelet transform unit, for by wavelet transformation, detects the peak values in real time of the invasive blood pressure signal collected and heavily rich point; Estimate unit, for the running status utilizing history invasive blood pressure Signal estimation to draw system, in conjunction with peak value and the heavily rich point of the invasive blood pressure signal of Real-time Collection, estimate the peak value of invasive blood pressure signal next time and the moment of heavily rich some appearance.
Further,
Described digital signal processor is: C6000 series of digital signals processor;
And/or described wavelet transform unit comprises: parameter determination module, for according to the characteristic of wavelet basis function and the feature of described invasive blood pressure signal, determine type and the Lifting Wavelet Decomposition order of wavelet basis function.
Further, described air-path control system comprises:
Inflation unit, inflated aorta after balloon for the moment occurred at upper once invasive blood pressure signal peak;
Deflating cells, exitted to aorta after balloon for the moment occurred at the heavily rich point of upper once invasive blood pressure signal;
Monitoring means, for carrying out Real-Time Monitoring to the air pressure of blood pressure and aorta after balloon inflation/deflation;
Suddenly stop unit, for manually stopping the heart change of burst.
Further, described system also comprises:
Host computer display control apparatus, is connected with described digital signal processor, for the conversion of the air pressure waveform of real-time monitored blood pressure and aorta after balloon inflation/deflation, carries out initial setting up by arranging the mode gathered or trigger to inflation/deflation gas circuit.
(3) beneficial effect
Visible, in the invasive blood pressure determination and analysis method and system that the present invention proposes, Real-time Collection can be carried out to invasive blood pressure, and carry out peak values in real time and heavily rich some detection, then control the inflation/deflation operation of aorta after balloon according to estimated lower minor peaks and a heavily rich moment occurred.The present invention by the real-time detection to invasive blood pressure, can realize the real-time control to aorta after balloon inflation/deflation in the anti-rich method of intra-aortic oalloon.
Accompanying drawing explanation
In order to be illustrated more clearly in the embodiment of the present invention or technical scheme of the prior art, be briefly described to the accompanying drawing used required in embodiment or description of the prior art below, apparently, accompanying drawing in the following describes is some embodiments of the present invention, for those of ordinary skill in the art, under the prerequisite not paying creative work, other accompanying drawing can also be obtained according to these accompanying drawings.
Fig. 1 is the basic procedure schematic diagram of embodiment of the present invention invasive blood pressure determination and analysis method;
Fig. 2 is the basic structure schematic diagram of embodiment of the present invention invasive blood pressure determination and analysis system;
Fig. 3 is the structural representation of a preferred embodiment of the invention invasive blood pressure determination and analysis system;
Fig. 4 is the schematic flow sheet of the embodiment of the present invention 1 invasive blood pressure determination and analysis method;
Fig. 5 is the detection block diagram of wavelet transformation in embodiment of the present invention invasive blood pressure determination and analysis method;
Fig. 6 is 128/80 peak value and the dicrotic pulse point testing result figure of the embodiment of the present invention 1 invasive blood pressure determination and analysis method;
Fig. 7 is 25/0 peak value and the dicrotic pulse point testing result figure of the embodiment of the present invention 1 invasive blood pressure determination and analysis method;
Fig. 8 is 14/4 peak value and the dicrotic pulse point testing result figure of the embodiment of the present invention 1 invasive blood pressure determination and analysis method;
Fig. 9 is the schematic flow sheet of the embodiment of the present invention 2 invasive blood pressure determination and analysis method.
Detailed description of the invention
For making the object of the embodiment of the present invention, technical scheme and advantage clearly, below in conjunction with the accompanying drawing in the embodiment of the present invention, technical scheme in the embodiment of the present invention is clearly and completely described, obviously, described embodiment is the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
First the embodiment of the present invention provides a kind of invasive blood pressure determination and analysis method, see Fig. 1, comprising:
Step 101: Real-time Collection is carried out to invasive blood pressure.
Step 102: peak values in real time and heavily rich some detection are carried out to the invasive blood pressure signal collected, and estimate the peak value of invasive blood pressure signal next time and a heavily rich moment occurred.
Step 103: in the moment occurred according to peak value and the heavily rich point of the described signal of invasive blood pressure next time, control the inflation/deflation operation of aorta after balloon.
Visible, in the invasive blood pressure determination and analysis method that the embodiment of the present invention proposes, Real-time Collection can be carried out to invasive blood pressure, and carry out peak values in real time and heavily rich some detection, then control the inflation/deflation operation of aorta after balloon according to estimated lower minor peaks and a heavily rich moment occurred.The embodiment of the present invention by the real-time detection to invasive blood pressure, can realize the real-time control to aorta after balloon inflation/deflation in the anti-rich method of intra-aortic oalloon.
In one embodiment of the invention, preferably, the blood pressure of femoral artery can be measured by puncture, measure the arterial pressure gathering femoral artery in real time.
In another embodiment of the present invention, after Real-time Collection is carried out to invasive blood pressure, and before the invasive blood pressure signal collected being carried out to peak values in real time and heavily rich some detection, filter amplifying processing can also be carried out to the circuit noise of the invasive blood pressure signal collected and needle position misalignment, and the invasive blood pressure analogue signal after process is carried out analog digital conversion.
In one embodiment of the invention, preferably, wavelet transform function can be used to detect the peak values in real time of the invasive blood pressure signal collected and heavily rich point.
In another embodiment of the present invention, preferably, estimating the moment that the peak value of invasive blood pressure signal next time and heavily rich point occur can comprise: utilize the running status accurately estimating system from history recursion till now, the transfer process of state is described with state equation, again in conjunction with peak value and the heavily rich point of the invasive blood pressure signal of this moment Real-time Collection, estimate the peak value of invasive blood pressure signal next time and the moment of heavily rich some appearance.
In one embodiment of the invention, need select suitable wavelet basis and determine Lifting Wavelet Decomposition order.Preferably, according to the feature of the characteristic of wavelet basis function and invasive blood pressure signal, the type Sum decomposition number of plies of wavelet basis function can be determined.
In another embodiment of the present invention, preferably, according to the moment that peak value and the heavily rich point of invasive blood pressure signal next time occur, the inflation/deflation operation controlling aorta after balloon can comprise: inflate aorta after balloon in the moment that upper once invasive blood pressure signal peak occurs, exits to aorta after balloon in the moment that the heavily rich point of upper once invasive blood pressure signal occurs.
In one embodiment of the invention, aorta after balloon is being carried out in the process of inflation/deflation, preferably, Real-Time Monitoring can carried out to the air pressure of inflation/deflation and blood pressure, to ensure not affect normal cardiomotility.Further, manually can also stop paroxysmal heart change, to ensure the life security not endangering patient.
In another embodiment of the present invention, preferably, the conversion of all right real-time monitored blood pressure, air pressure waveform, carries out initial setting up by arranging the mode gathered or trigger to inflation/deflation gas circuit.
The embodiment of the present invention also proposes a kind of invasive blood pressure determination and analysis system, see Fig. 2, comprising:
Invasive blood pressure acquisition system 1, for carrying out Real-time Collection to invasive blood pressure;
Digital signal processor 2, for carrying out peak values in real time and heavily rich some detection to the invasive blood pressure signal collected, and estimates the peak value of invasive blood pressure signal next time and a heavily rich moment occurred;
Air-path control system 3, comprises aorta after balloon 4, for the moment occurred according to peak value and the heavily rich point of the described signal of invasive blood pressure next time, controls the inflation/deflation operation of aorta after balloon.
In one embodiment of the invention, preferably, invasive blood pressure acquisition system 1 can comprise: invasive blood pressure sensor system, comprise ductus arteriosus, pressure connection tube, pressure transducer, continuous flushing system and invasive blood pressure sensor, for being measured the blood pressure of femoral artery by puncture, measure the arterial pressure gathering femoral artery in real time.
At human body parts, first ductus arteriosus is passed through puncture, be placed in the Ink vessel transfusing at tested position, the outer end of ductus arteriosus is directly connected with invasive blood pressure sensor, because fluid has pressure transmission effect, endovascular pressure by by the liquid transfer in ductus arteriosus in the invasive blood pressure sensor of outside, thus the dynamic waveform of Ink vessel transfusing real-time pressure change can be obtained.
To note when carrying out invasive blood pressure and measuring: when monitoring starts, first school zero is carried out to pressure transducer; In observation process, keep invasive blood pressure sensor and heart at any time in same level; For preventing ductus arteriosus from blocking, constantly to inject heparin saline and rinsing ductus arteriosus, to keep the unobstructed of pressure measurement pathway; To ductus arteriosus be fixedly secured simultaneously, prevent arterial catheter sites from moving or deviate from, affect the measurement of invasive blood pressure.
In another embodiment of the present invention, preferably, system can also comprise: signal processing unit 5, as Fig. 3, is connected between invasive blood pressure acquisition system 1 and digital signal processor 2.Signal processing unit 5 can comprise low-noise operational amplifier, amplifying circuit and 16 modulus (AD, analog to digital) transducer, by adopting low-noise operational amplifier to build filtering and amplifying circuit processes circuit noise and needle position misalignment, and the simulation blood pressure signal after process is carried out analog digital conversion by 16 AD devices.
In one embodiment of the invention, preferably, digital signal processor 2 can comprise: wavelet transform unit, for by wavelet transformation, detects the peak values in real time of the invasive blood pressure signal collected and heavily rich point.
In another embodiment of the present invention, preferably, digital signal processor 2 can also comprise: estimate unit, for the running status utilizing history invasive blood pressure Signal estimation to draw system, in conjunction with peak value and the heavily rich point of the invasive blood pressure signal of Real-time Collection, estimate the peak value of invasive blood pressure signal next time and the moment of heavily rich some appearance.
In one embodiment of the invention, preferably, digital signal processor (DSP, DigitalSignalProcessing) 2 can be: C6000 series of digital signals processor, meet internal memory in strong, a large amount of date processing of operational capability and abundant peripheral hardware and a large amount of sheets, to meet wavelet transformation to invasive blood pressure and operation control.
In another embodiment of the present invention, need select suitable wavelet basis and determine Lifting Wavelet Decomposition order.Preferably, wavelet transform unit can comprise: parameter determination module, for according to the characteristic of wavelet basis function and the feature of invasive blood pressure signal, determines the type Sum decomposition number of plies of wavelet basis function.
In another embodiment of the present invention, preferably, air-path control system 3 can comprise proportioning valve, electromagnetic valve, air accumulator, aorta after balloon, conduit etc., and main realization regulates the air pressure of gas circuit and aorta after balloon carried out to the operation of inflation/deflation.Gas circuit is arranged needs fast reaction, and time delay can not be oversize.The size of aorta after balloon is selected by the height according to human body, and the blowing pressure has pressure transducer Real-Time Monitoring.The moment that air-path control system 3 occurs according to the peak value of invasive blood pressure signal next time and heavily rich point, control in the inflation/deflation operation of aorta after balloon, can comprise: inflation unit, for the moment occurred at upper once invasive blood pressure signal peak, aorta after balloon be inflated; Deflating cells, exitted to aorta after balloon for the moment occurred at the heavily rich point of upper once invasive blood pressure signal; Monitoring means, for the air pressure to blood pressure and aorta after balloon inflation/deflation, carries out Real-Time Monitoring by pressure transducer; Suddenly stop unit, for manually stopping the heart change of burst.
In another embodiment of the present invention, preferably, system can also comprise: host computer display control apparatus 6, be connected with digital signal processor 2, for the conversion of the air pressure waveform of real-time monitored blood pressure and aorta after balloon inflation/deflation, by arranging the mode gathered or trigger, initial setting up is carried out to inflation/deflation gas circuit.
Below to describe the implementation step of the embodiment of the present invention in detail, specifically introduce the implementation procedure of invasive blood pressure determination and analysis method.
Embodiment 1:
The embodiment of the present invention 1 is the embodiment of being carried out invasive blood pressure determination and analysis method by blood pressure analog meter.
Step 401: connect blood pressure analog meter and invasive blood pressure acquisition system 1.
In this step, first need to arrange suitable joint, connect blood pressure analog meter and invasive blood pressure acquisition system 1.Be familiar with the invasive blood pressure joint definition of blood pressure analog meter, and after the blood pressure acquisition channel interface definition of invasive blood pressure acquisition system 1, be welded to connect line and connect blood pressure analog meter and invasive blood pressure acquisition system 1.
Step 402: connect invasive blood pressure acquisition system 1 and digital signal processor 2, digital signal processor 2 and air-path control system 3, air-path control system 3 and host computer display control apparatus 6.
In air-path control system 3, be also connected with aorta after balloon 4 at catheter tip, to verify inflation/deflation effect.
Step 403: switch on power, controls blood pressure analog meter and exports.
In this step, the amplitude exported blood pressure analog meter is needed to carry out adjustment to difference Detection results.Wherein output signal comprises: 120/80, the invasive blood pressure signal of 25/0,14/4.
Step 404: the invasive blood pressure signal that blood pressure analog meter exports is processed.
In this step, utilize signal processing unit to adopt low-noise operational amplifier to build filtering to the invasive blood pressure signal that collects and amplifying circuit processes circuit noise and needle position misalignment, and the simulation invasive blood pressure signal after process is carried out analog digital conversion by 16 AD devices.
Step 405: run digital signal processor 2 and wavelet transformation detection is carried out to the invasive blood pressure signal after process.
Digital signal processor 2 can realize the sample record of invasive blood pressure signal, the communication of host computer display control apparatus 6, wavelet transformation detect blood pressure peak value and heavily rich point, the function such as to communicate of air-path control system 3.
Wherein, the C6000 series of digital signals processor that digital signal processor 2 adopts current speed relatively high, and the interface utilizing it good is arranged, conveniently carry out detection and the process programming of invasive blood pressure signal, and signal can be uploaded to host computer display control apparatus 6 and show.Host computer display control apparatus 6 can real-time monitored blood pressure, aorta after balloon inflation/deflation the conversion of air pressure waveform, and can by arranging collection or triggering mode carries out some initial settings to gas circuit.
Digital signal processor 2 comprises wavelet transform unit, can pass through wavelet transformation, detects the peak values in real time of the invasive blood pressure signal collected and heavily rich point.Fig. 5 represents the partial process view that wavelet transformation detects, and can pass through first wavelet transformation and detect the peak value of invasive blood pressure signal, then search for the algorithm of heavily rich point according to peak value, detects the peak values in real time of invasive blood pressure signal and heavily rich point.Wavelet transform unit also comprises estimates unit, with the running status utilizing history invasive blood pressure Signal estimation to draw system, in conjunction with peak value and the heavily rich point of the invasive blood pressure signal of Real-time Collection, estimate the peak value of invasive blood pressure signal next time and the moment of heavily rich some appearance.And the estimated moment is sent to air-path control system 3.
Wherein, to blood pressure analog meter export respectively be 120/80,25/0,14/4 the result that detects of invasive blood pressure signal respectively as shown in Figure 6 to 8, in figure, BHBuffer and BBBuffer short-term represents peak-location information.As seen from the figure, this method accurately can indicate the peak value of invasive blood pressure signal and the positional information of heavily rich point.
Step 406: in the moment occurred according to peak value and the heavily rich point of invasive blood pressure signal next time, control the inflation/deflation operation of aorta after balloon.
In this step, first air-path control system 3 hunts leak to gas circuit, then according to the moment that peak value and the heavily rich point of the signal of invasive blood pressure next time received occur, controls the inflation/deflation operation of aorta after balloon.Wherein, the moment utilizing inflation unit to occur at upper once invasive blood pressure signal peak inflates aorta after balloon, and the moment utilizing deflating cells to occur at the heavily rich point of upper once invasive blood pressure signal exits to aorta after balloon.
Air-path control system 3 can also carry out Real-Time Monitoring by the air pressure of monitoring means to blood pressure and aorta after balloon inflation/deflation.
So far, then the overall process of invasive blood pressure determination and analysis in the embodiment of the present invention 1 is completed.
Embodiment 2:
The embodiment of the present invention 2 is the embodiment of human body being carried out to invasive blood pressure determination and analysis method.For in practical application, we take the scheme as embodiment 1, when critical patient is as shock patient, some operation on heart and other capital operations, the monitoring of real-time change is carried out to blood pressure and wins to heart increasing blood supply by sacculus is counter, thus saving the life of patient.Wherein, blood pressure analog meter can be replaced by human body parts.
Step 901: connect human body and invasive blood pressure acquisition system 1.
At human body parts, first the ductus arteriosus in invasive blood pressure acquisition system 1 is passed through puncture, be placed in the Ink vessel transfusing at tested position, the outer end of ductus arteriosus is directly connected with invasive blood pressure sensor, because fluid has pressure transmission effect, endovascular pressure by by the liquid transfer in ductus arteriosus in the invasive blood pressure sensor of outside, thus the dynamic waveform of Ink vessel transfusing real-time pressure change can be obtained.
To note when carrying out invasive blood pressure and measuring: when monitoring starts, first school zero is carried out to pressure transducer; In observation process, keep invasive blood pressure sensor and heart at any time in same level; For preventing ductus arteriosus from blocking, constantly to inject heparin saline and rinsing ductus arteriosus, to keep the unobstructed of pressure measurement pathway; To ductus arteriosus be fixedly secured simultaneously, prevent arterial catheter sites from moving or deviate from, affect the measurement of invasive blood pressure.
Step 902 is identical to step 406 with step 402 to step 906, and, in the site of puncture of human body, need by conduit, aorta after balloon to be goed deep in stock aorta, arrive the neighbouring position of heart, to strengthen the blood supply to heart.Also including in air-path control system 3 and suddenly stop unit, for manually stopping paroxysmal heart change, ensureing the life security not endangering patient.
So far, then the overall process of human body invasive blood pressure determination and analysis in the embodiment of the present invention 2 is completed.
Visible, the embodiment of the present invention has following beneficial effect:
In the invasive blood pressure determination and analysis method and system that the embodiment of the present invention proposes, Real-time Collection can be carried out to invasive blood pressure, and carry out peak values in real time and heavily rich some detection, the inflation/deflation operation of aorta after balloon is then controlled according to estimated lower minor peaks and a heavily rich moment occurred.The embodiment of the present invention by the real-time detection to invasive blood pressure, can realize the real-time control to aorta after balloon inflation/deflation in the anti-rich method of intra-aortic oalloon.
Last it is noted that above embodiment is only in order to illustrate technical scheme of the present invention, be not intended to limit; Although with reference to previous embodiment to invention has been detailed description, those of ordinary skill in the art is to be understood that: it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature; And these amendments or replacement, do not make the essence of appropriate technical solution depart from the spirit and scope of various embodiments of the present invention technical scheme.

Claims (10)

1. an invasive blood pressure determination and analysis method, is characterized in that, comprising:
Real-time Collection is carried out to invasive blood pressure;
Peak values in real time and heavily rich some detection are carried out to the invasive blood pressure signal collected, and estimates the peak value of invasive blood pressure signal next time and a heavily rich moment occurred;
According to the moment that peak value and the heavily rich point of the described signal of invasive blood pressure next time occur, control the inflation/deflation operation of aorta after balloon.
2. invasive blood pressure determination and analysis method according to claim 1, is characterized in that:
Describedly Real-time Collection is carried out to invasive blood pressure comprise: the blood pressure being measured femoral artery by puncture, measure the arterial pressure gathering femoral artery in real time;
Described Real-time Collection is carried out to invasive blood pressure after, and also comprised before the described invasive blood pressure signal to collecting carries out peak values in real time and heavily rich point detects: filter amplifying processing is carried out to the circuit noise of the invasive blood pressure signal collected and needle position misalignment, and the invasive blood pressure analogue signal after process is carried out analog digital conversion;
The described invasive blood pressure signal to collecting carries out peak values in real time and the detection of heavily rich point comprises: by wavelet transformation, detects the peak values in real time of the invasive blood pressure signal collected and heavily rich point;
The moment of the described peak value and heavily rich some appearance of estimating invasive blood pressure signal next time comprises: utilize history invasive blood pressure Signal estimation to draw the running status of system, in conjunction with peak value and the heavily rich point of the invasive blood pressure signal of Real-time Collection, estimate the peak value of invasive blood pressure signal next time and the moment of heavily rich some appearance.
3. invasive blood pressure determination and analysis method according to claim 2, it is characterized in that, describedly pass through wavelet transformation, the peak values in real time and the heavily rich point that detect the invasive blood pressure signal collected also comprise: according to the characteristic of wavelet basis function and the feature of described invasive blood pressure signal, determine type and the Lifting Wavelet Decomposition order of wavelet basis function.
4. invasive blood pressure determination and analysis method according to claim 1, is characterized in that, in moment of occurring of the peak value of invasive blood pressure signal and heavily rich point next time described in described basis, the inflation/deflation operation controlling aorta after balloon comprises:
In the moment that upper once invasive blood pressure signal peak occurs, aorta after balloon is inflated, in the moment that the heavily rich point of upper once invasive blood pressure signal occurs, aorta after balloon is exitted;
Real-Time Monitoring is carried out to the air pressure of blood pressure and aorta after balloon inflation/deflation; The heart change of burst is manually stopped.
5. invasive blood pressure determination and analysis method according to any one of claim 1 to 4, it is characterized in that, described method also comprises: carry out initial setting up by arranging the mode gathered or trigger to inflation/deflation gas circuit.
6. an invasive blood pressure determination and analysis system, is characterized in that, comprising: invasive blood pressure acquisition system, digital signal processor and air-path control system that order is connected, wherein:
Invasive blood pressure acquisition system, for carrying out Real-time Collection to invasive blood pressure;
Digital signal processor, for carrying out peak values in real time and heavily rich some detection to the invasive blood pressure signal collected, and estimates the peak value of invasive blood pressure signal next time and a heavily rich moment occurred;
Air-path control system, comprises aorta after balloon, for the moment occurred according to peak value and the heavily rich point of the described signal of invasive blood pressure next time, controls the inflation/deflation operation of aorta after balloon.
7. invasive blood pressure determination and analysis system according to claim 6, is characterized in that:
Described invasive blood pressure acquisition system comprises: invasive blood pressure sensor system, comprise ductus arteriosus, pressure connection tube, pressure transducer, continuous flushing system and invasive blood pressure sensor, for being measured the blood pressure of femoral artery by puncture, measure the arterial pressure gathering femoral artery in real time;
Described system also comprises: signal processing unit, be connected between described invasive blood pressure acquisition system and described digital signal processor, comprise low-noise operational amplifier, amplifying circuit and 16 analog-digital converters, for carrying out filter amplifying processing to the circuit noise of the invasive blood pressure signal collected and needle position misalignment, and the invasive blood pressure analogue signal after process is carried out analog digital conversion;
Described digital signal processor comprises: wavelet transform unit, for by wavelet transformation, detects the peak values in real time of the invasive blood pressure signal collected and heavily rich point; Estimate unit, for the running status utilizing history invasive blood pressure Signal estimation to draw system, in conjunction with peak value and the heavily rich point of the invasive blood pressure signal of Real-time Collection, estimate the peak value of invasive blood pressure signal next time and the moment of heavily rich some appearance.
8. invasive blood pressure determination and analysis system according to claim 7, is characterized in that:
Described digital signal processor is: C6000 series of digital signals processor;
And/or described wavelet transform unit comprises: parameter determination module, for according to the characteristic of wavelet basis function and the feature of described invasive blood pressure signal, determine type and the Lifting Wavelet Decomposition order of wavelet basis function.
9. invasive blood pressure determination and analysis system according to claim 6, it is characterized in that, described air-path control system comprises:
Inflation unit, inflated aorta after balloon for the moment occurred at upper once invasive blood pressure signal peak;
Deflating cells, exitted to aorta after balloon for the moment occurred at the heavily rich point of upper once invasive blood pressure signal;
Monitoring means, for carrying out Real-Time Monitoring to the air pressure of blood pressure and aorta after balloon inflation/deflation;
Suddenly stop unit, for manually stopping the heart change of burst.
10. the invasive blood pressure determination and analysis system according to any one of claim 6 to 9, it is characterized in that, described system also comprises:
Host computer display control apparatus, is connected with described digital signal processor, for the conversion of the air pressure waveform of real-time monitored blood pressure and aorta after balloon inflation/deflation, carries out initial setting up by arranging the mode gathered or trigger to inflation/deflation gas circuit.
CN201310646565.2A 2013-12-04 2013-12-04 Invasive blood pressure detecting and analyzing method and system Pending CN104688209A (en)

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