CN104665875A - Ultrasonic Doppler envelope and heart rate detection method - Google Patents

Ultrasonic Doppler envelope and heart rate detection method Download PDF

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CN104665875A
CN104665875A CN201510068330.9A CN201510068330A CN104665875A CN 104665875 A CN104665875 A CN 104665875A CN 201510068330 A CN201510068330 A CN 201510068330A CN 104665875 A CN104665875 A CN 104665875A
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heart rate
ultrasonic signal
envelope
infin
kalman
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覃正笛
覃道鼎
李�杰
陈思平
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Shenzhen University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/02Measuring pulse or heart rate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/48Diagnostic techniques
    • A61B8/488Diagnostic techniques involving Doppler signals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/52Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/5215Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data
    • A61B8/5223Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for extracting a diagnostic or physiological parameter from medical diagnostic data
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16ZINFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS, NOT OTHERWISE PROVIDED FOR
    • G16Z99/00Subject matter not provided for in other main groups of this subclass

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Abstract

The invention relates to an ultrasonic Doppler envelope and heart rate detection method which comprises the following steps: constructing an adaptive model for an acquired ultrasonic signal; carrying out Kalman tracking filtering on the ultrasonic signal in the constructed adaptive model; carrying out wavelet transformation on the ultrasonic signal subjected to kalman tracking filtering to finish detection of the Doppler envelope and the heart rate in the ultrasonic signal. According to the method, the Doppler envelope and the heart rate can be directly extracted from an original signal; double frequency interference can be overcome, the robustness is high, and the speed is high.

Description

Ultrasonic doppler envelope and heart rate detection method
Technical field
The present invention relates to a kind of ultrasonic doppler envelope and heart rate detection method.
Background technology
At present, the method realizing envelope detected and heart rate calculating mainly contains Hilbert-Huang transform method, mathematical mor-phology method, average shannon energy method.
But Hilbert-Huang transform method extracts envelope can produce a large amount of burr, the envelope curve obtained is level and smooth not, thus impact treatment and analysis below.Although adopt mathematical mor-phology to extract the method for envelope simply, but the quality of its performance is relevant to structural element, and the experience of the selective dependency algorithm author of structural element, and the envelope curve peak value that profit obtains in this way is not obvious, cannot reflect accurate location.Average shannon energy method then needs the average energy of signal calculated within a period of time, and this can cause the time-domain position of signal to offset, and therefore utilizes shannon energy method to extract temporal signatures and can there is larger error.
Summary of the invention
In view of this, be necessary to provide a kind of ultrasonic doppler envelope and heart rate detection method.
The invention provides a kind of ultrasonic doppler envelope and heart rate detection method, comprise the steps: that a. is that the ultrasonic signal obtained sets up adaptive model; B. in the adaptive model of above-mentioned foundation, Kalman tracking filter is carried out to described ultrasonic signal; C. wavelet transformation is carried out to the ultrasonic signal after described Kalman tracking filter, complete the detection to the Doppler's envelope in described ultrasonic signal and heart rate.
Adaptive model in described step a is: y k + 1 = A k y k + B k u k + Γ k ξ k w k = C k y k + D k u k + η k ,
Wherein, A k, B k, Γ k, C k, D kknown constant value matrix respectively, ξ k, η ksystem and the observation noise sequence of the statistical information such as known average, variance and covariance respectively.
Described step b specifically comprises: adopt formula x k | k ^ = x k | k - 1 ^ + G k ( v k - C k x k | k - 1 ^ ) x k | k - 1 ^ = A k - 1 x k - 1 | k - 1 ^ Real-time tracking calculates x k, wherein, G kfor kalman gain matrix; Adopt formula P 0,0 = Var ( x 0 ) P k , k - 1 = A k - 1 P k - 1 , k - 1 A k - 1 T + Γ k - 1 Q k - 1 Γ k - 1 T G k = P k , k - 1 C k T ( C k P k , k - 1 C k T + R k ) - 1 P k , k = ( 1 - G k C k ) P k , k - 1 x 0 | 0 ^ = E ( x 0 ) x k | k - 1 ^ = A k - 1 x k - 1 | k - 1 ^ + B k - 1 u k - 1 x k | k ^ = x k | k - 1 ^ + G k ( v k - D k u k - C k x k | k - 1 ^ ) k = 1,2 , L Carry out Kalman tracking filter, wherein x is the noisy signal of band obtained.
Described step c specifically comprises: utilize formula carry out small echo integral transformation, wherein for wavelet function; Utilize formula x ( i , n ) = Σ k = - ∞ ∞ h ( 2 k - n ) x L ( i - 1 , k ) + Σ k = - ∞ ∞ g ( 2 k - n ) x H ( i - 1 , k ) Carry out wavelet transform.
A kind of ultrasonic doppler envelope of the present invention and heart rate detection method, can Doppler's envelope in extracting directly ultrasonic signal and heart rate.Through a large amount of data tests, find that accuracy of the present invention is very high, in very large noise circumstance, correct result can both be detected, and do not need any priori knowing signal, also not need to set threshold value, the most valuable, the present invention does not disturb by so-called double frequency.And double frequency interference is the difficult point in ultrasonic continuous wave Doppler heart rate detection.And the envelope curve that the present invention obtains is level and smooth, peak point position is given prominence to, for subsequent analysis process provides great convenience.
Accompanying drawing explanation
Fig. 1 is the flow chart of ultrasonic doppler envelope of the present invention and heart rate detection method.
Fig. 2 is the embodiment of the present invention to 20 seconds result schematic diagrams with noisy sample of signal.
Detailed description of the invention
Below in conjunction with drawings and the specific embodiments, the present invention is further detailed explanation.
Consulting shown in Fig. 1, is the operation process chart of ultrasonic doppler envelope of the present invention and heart rate detection method preferred embodiment.
Step S401, for the ultrasonic signal obtained sets up adaptive model.Specifically:
First, set up a model, consider a linear system in state space description:
y k + 1 = A k y k + B k u k + Γ k ξ k w k = C k y k + D k u k + η k - - - ( 1 )
In formula, A k, B k, Γ k, C k, D kknown constant value matrix respectively, ξ k, η kbeing system and the observation noise sequence of the statistical information such as known average, variance and covariance respectively, is unknown.Wherein, ξ is supposed k, η kzero mean Gaussian white noise sequence, at original state x 0with ξ k, η kindependent.
Determining x koptimal estimation time, optimality is that the minimum variance estimate under the method for least square meaning by selecting best initial weights matrix to provide obtains.As j=k, definition as j<k, definition for x koptimal estimation; As j>k, definition for x klevel and smooth estimation.Wherein j=0,1, L k.The present embodiment discusses the situation of j=k.
Step S402, carries out Kalman tracking filter to described ultrasonic signal in the adaptive model of above-mentioned foundation.
Following formula real-time tracking is adopted to calculate x k:
x k | k ^ = x k | k - 1 ^ + G k ( v k - C k x k | k - 1 ^ ) x k | k - 1 ^ = A k - 1 x k - 1 | k - 1 ^ - - - ( 2 )
In formula, G kfor kalman gain matrix.
Starting point initial estimation is because original state x 0unbiased esti-mator, can use constant value vector and in the Kalman filtering of reality, G kalso necessary recurrence calculation, these two processes are exactly Kalman filtering process altogether.Be summarized as follows:
P 0,0 = Var ( x 0 ) P k , k - 1 = A k - 1 P k - 1 , k - 1 A k - 1 T + &Gamma; k - 1 Q k - 1 &Gamma; k - 1 T G k = P k , k - 1 C k T ( C k P k , k - 1 C k T + R k ) - 1 P k , k = ( 1 - G k C k ) P k , k - 1 x 0 | 0 ^ = E ( x 0 ) x k | k - 1 ^ = A k - 1 x k - 1 | k - 1 ^ + B k - 1 u k - 1 x k | k ^ = x k | k - 1 ^ + G k ( v k - D k u k - C k x k | k - 1 ^ ) k = 1,2 , L - - - ( 3 )
Wherein, x is the noisy signal of band obtained.
Step S403, carries out wavelet transformation to the ultrasonic signal after described Kalman tracking filter, completes the detection to the Doppler's envelope in described ultrasonic signal and heart rate.
Small echo, by two shirtsleeve operations " translation " and " stretching ", is realized by " wavelet basis " family of functions.If be a wavelet basis function, in conjunction with flexible constant a and translation constant b, obtaining a series of form is wavelet function.With a kind of integral transformation for integral kernel defines of described wavelet function, be called small echo integral transformation:
Wavelet transform is as follows:
x ( i , n ) = &Sigma; k = - &infin; &infin; h ( 2 k - n ) x L ( i - 1 , k ) + &Sigma; k = - &infin; &infin; g ( 2 k - n ) x H ( i - 1 , k ) - - - ( 5 )
In the embodiment of the present invention 20 seconds with the data of random noise after small echo Kalman filtering, just time-domain signal can be converted to frequency-region signal, obtain the large small component of frequency, as shown in Figure 2.
The present invention utilizes modern signal processing, directly can extract Doppler's envelope and heart rate from primary signal, any priori of undesired signal, does not also need to set any threshold value; , adopt Kalman adaptive technique, smooth envelope curve can be obtained, and the interference of double frequency can be overcome well; Adopt adaptive tracing technology, robustness is good, and the segment signal specially picking noise in experiment larger is verified, the envelope curve obtained still unusual light, and heart rate result of calculation is very accurate; Under PC platform (AMD Athlon II X4635), computational speed is quickly in application the present invention, about 0.25 second of the processing time of 20 number of seconds certificates, therefore in real-time embedded system, current MCU can be competent at completely, LCD is coordinated to show again, so just can well by the present invention's marketization.
Although the present invention is described with reference to current better embodiment; but those skilled in the art will be understood that; above-mentioned better embodiment is only used for the present invention is described; not be used for limiting protection scope of the present invention; any within the spirit and principles in the present invention scope; any modification of doing, equivalence replacement, improvement etc., all should be included within the scope of the present invention.

Claims (4)

1. ultrasonic doppler envelope and a heart rate detection method, is characterized in that, the method comprises the steps:
A. the ultrasonic signal for obtaining sets up adaptive model;
B. in the adaptive model of above-mentioned foundation, Kalman tracking filter is carried out to described ultrasonic signal;
C. wavelet transformation is carried out to the ultrasonic signal after described Kalman tracking filter, complete the detection to the Doppler's envelope in described ultrasonic signal and heart rate.
2. the method for claim 1, is characterized in that, the adaptive model in described step a is:
y k + 1 = A k y k + B k u k + &Gamma; k &xi; k w k = C k y k + D k u k + &eta; k ,
Wherein, A k, B k, Γ k, C k, D kknown constant value matrix respectively, ξ k, η ksystem and the observation noise sequence of the statistical information such as known average, variance and covariance respectively.
3. the method for claim 1, is characterized in that, described step b specifically comprises:
Adopt formula x k | k ^ = x k | k - 1 ^ + G k ( v k - G k x k | k - 1 ^ ) x k | k - 1 ^ = A k - 1 x k - 1 | k - 1 ^ Real-time tracking calculates x k, wherein, G kfor kalman gain matrix;
Adopt formula P 0,0 = Var ( x 0 ) P k , k - 1 = A k - 1 P k - 1 , k - 1 A k - 1 T + &Gamma; k - 1 Q k - 1 &Gamma; k - 1 T G k = P k , k - 1 C k T ( C k P k , k - 1 C k T + R k ) - 1 P k , k = ( 1 - G k C k ) P k , k - 1 x 0 | 0 ^ = E ( x 0 ) x k | k - 1 = A k - 1 x k - 1 | k - 1 ^ ^ + B k - 1 u k - 1 x k | k ^ = x k | k - 1 ^ + G k ( v k - D k u k - C k x k | k - 1 ^ ) k = 1,2 , L Carry out Kalman tracking filter, wherein x is the noisy signal of band obtained.
4. the method for claim 1, is characterized in that, described step c specifically comprises:
Utilize formula carry out small echo integral transformation, wherein for wavelet function;
Utilize formula x ( i , n ) = &Sigma; k = - &infin; &infin; h ( 2 k - n ) x L ( i - 1 , k ) + &Sigma; k = - &infin; &infin; g ( 2 k - n ) x H ( i - 1 , k ) Carry out wavelet transform.
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Cited By (5)

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CN106137255A (en) * 2016-07-21 2016-11-23 深圳大学 A kind of digital Doppler's fetal rhythm wireless probe based on bluetooth and detection method
CN106510763A (en) * 2016-09-19 2017-03-22 来安中衡物联网设备科技有限公司 Blood relationship spectrum imaging method and device
CN110269642A (en) * 2019-06-28 2019-09-24 中南大学 Doppler's heart rate estimation method based on Fourier Transform of Fractional Order and wavelet transformation
CN113343784A (en) * 2021-05-18 2021-09-03 中国科学院深圳先进技术研究院 Signal processing system and method based on ultrasonic contrast imaging technology and terminal equipment
WO2022241650A1 (en) * 2021-05-18 2022-11-24 中国科学院深圳先进技术研究院 Contrast-enhanced ultrasound technology-based signal processing system and method, and terminal device

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106137255A (en) * 2016-07-21 2016-11-23 深圳大学 A kind of digital Doppler's fetal rhythm wireless probe based on bluetooth and detection method
CN106510763A (en) * 2016-09-19 2017-03-22 来安中衡物联网设备科技有限公司 Blood relationship spectrum imaging method and device
CN110269642A (en) * 2019-06-28 2019-09-24 中南大学 Doppler's heart rate estimation method based on Fourier Transform of Fractional Order and wavelet transformation
CN110269642B (en) * 2019-06-28 2020-06-09 中南大学 Doppler heart rate estimation method based on fractional Fourier transform and wavelet transform
CN113343784A (en) * 2021-05-18 2021-09-03 中国科学院深圳先进技术研究院 Signal processing system and method based on ultrasonic contrast imaging technology and terminal equipment
WO2022241650A1 (en) * 2021-05-18 2022-11-24 中国科学院深圳先进技术研究院 Contrast-enhanced ultrasound technology-based signal processing system and method, and terminal device

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