CN104644224B - In-vivo experimental mouse intestinal canal inner wall cell scraping device - Google Patents
In-vivo experimental mouse intestinal canal inner wall cell scraping device Download PDFInfo
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- CN104644224B CN104644224B CN201510068325.8A CN201510068325A CN104644224B CN 104644224 B CN104644224 B CN 104644224B CN 201510068325 A CN201510068325 A CN 201510068325A CN 104644224 B CN104644224 B CN 104644224B
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- pipe
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- capsule
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- 238000007790 scraping Methods 0.000 title claims abstract description 16
- 230000000968 intestinal effect Effects 0.000 title abstract description 18
- 238000001727 in vivo Methods 0.000 title abstract 3
- 239000002775 capsule Substances 0.000 claims description 51
- 241000700159 Rattus Species 0.000 claims description 18
- 210000000936 intestine Anatomy 0.000 claims description 13
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 9
- 239000000741 silica gel Substances 0.000 claims description 9
- 229910002027 silica gel Inorganic materials 0.000 claims description 9
- 239000000725 suspension Substances 0.000 claims description 9
- 239000000463 material Substances 0.000 claims description 3
- 229910000831 Steel Inorganic materials 0.000 claims description 2
- 239000010959 steel Substances 0.000 claims description 2
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 3
- 230000035479 physiological effects, processes and functions Effects 0.000 abstract description 3
- 238000004519 manufacturing process Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 9
- 239000010935 stainless steel Substances 0.000 description 4
- 229910001220 stainless steel Inorganic materials 0.000 description 4
- 238000010586 diagram Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 241000257468 Asterias amurensis Species 0.000 description 1
- 241000252254 Catostomidae Species 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 240000007817 Olea europaea Species 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 239000000084 colloidal system Substances 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000001050 lubricating effect Effects 0.000 description 1
- 230000000873 masking effect Effects 0.000 description 1
- 230000003340 mental effect Effects 0.000 description 1
- 238000004080 punching Methods 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- -1 suction bags Substances 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
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Abstract
The invention relates to the technical field of zootomy physiology and particularly discloses an in-vivo experimental mouse intestinal canal inner wall cell scraping device which comprises a movable sucking ball, a suction and delivery pipe and an operation bag, wherein the movable sucking ball comprises an outer wall, an inner wall and an air inflation cabin; the inner wall is provided with a forward-moving tube foot and a backing tube foot; the front end of the movable sucking ball is provided with a movable sucking ball neck and a movable sucking ball head; the movable sucking ball head is internally provided with a scraping line; the front end of the movable sucking ball head is provided with a pick-up camera and a flash lamp. By use of the flexibility and certain non-malleable property of a thread rope, the internal surface of an intestinal canal which protrudes and is tensioned after being adsorbed is scraped by the tensioned thread rope, so that the purposes of not only ensuring that an experimental mouse is not killed, but also obtaining intestinal canal internal surface cells are achieved; The in-vivo experimental mouse intestinal canal inner wall cell scraping device is simple to manufacture, high in operability, low in cost and obvious in effect.
Description
(1) technical field
The present invention relates to zootomy physiology's technical field, particularly to a kind of experiment made on the living intestine in rats tapetum cell
Scraping device.
(2) background technology
At present, in a lot of zootomy Physiology Experiments are studied, it is required for intestinal tapetum cell.But, obtain these
The method of cell is all to be killed by experimental rat, then cuts intestinal, then obtains these cells.Result of which one be by
Rat kills, and has injured a life, it addition, put to death during, to experimenter also result in certain mental pressure and
Potential danger.
(3) summary of the invention
The present invention is in order to make up the defect of prior art, it is provided that a kind of live body that need not kill intestine in rats tapetum cell
Experimental rat intestinal tapetum cell scraping device.
The present invention is achieved through the following technical solutions:
A kind of experiment made on the living intestine in rats tapetum cell scraping device, is characterized in that: the olive-type including being sequentially connected with
Dynamic suction ball, suction and conveying pipe and operation capsule, described dynamic suction ball is followed successively by the inwall of the outer wall of silica gel material, stainless steel from outside to inside
With inflation cabin, the two ends of described outer wall and inwall are joined together to form flexible cabin, and described inwall front end is sequentially connected with by silica gel
The dynamic suction ball neck that film is made and dynamic bulb of inhaling, described dynamic suction ball neck and dynamic inhale truncated cone-shaped that bulb is all hollow and they under
The end, links together, and the end of described dynamic suction bulb is provided with at least one photographic head and at least one flash lamp, described dynamic suction ball
What head inner surface was provided with that ordered series of numbers radially distributes nonelastic scrapes line taking；Count from front end the 1/10 of the outer surface of described inwall
～be provided with at 3,/10 2～5 circle before line pipes foot, the outer surface of described inwall at 1/10～3/10 that rear end is counted, be provided with 2～5
Circle retreats pipe foot, described front line pipe foot and in retreating the pipe pedal aperture that is all located on outer wall of top of pipe foot, described front line pipe foot and
Retreating pipe foot structure identical, they all include: have the cylindric pipe foot wall that resilient silica gel is made, serve as reasons bottom pipe foot wall
The pipe vola that pellosil is made, described pipe vola sticks on inboard wall outer surface, is provided with out crannied control in described pipe foot wall
Masking, described control film periphery is connected with pipe foot wall inwall, and described pipe foot wall upper end is provided with cake at the bottom of sucker, and cake at the bottom of described sucker leads to
Crossing ring cake connecting rod and ring cake support ring to be connected with pipe foot wall inwall, at the bottom of described sucker, between cake and pipe vola, connection has inelastic
Suspension, the length of described suspension, less than the height of pipe foot wall, the pipe foot wall between pipe vola and control film connects and has pipe
Foot pipe, the pipe foot Guan Yuqian line pipe through connection of toe ring pipe on all front line pipes foot, described front line pipe toe ring pipe is provided with and moves ahead
Pipe foot keyholed back plate, pipe toe ring pipe is through is connected with retrogressing for the pipe foot pipe on all retrogressing pipes foot, and described retrogressing pipe toe ring pipe is provided with
Retreat pipe foot keyholed back plate；Described front line pipe toe ring pipe and retrogressing pipe toe ring pipe at front line pipe foot and retreat between pipe foot；Described fill
Gas cabin connects gas tube；Being provided with in described operation capsule moves ahead pushes away capsule, suction bags, gas cell and retrogressing and pushes away capsule, described dynamic suction ball
Neck connects has pipette, described pipette to sequentially pass through inflation cabin and suction and conveying pipe is through with suction bags is connected, and described front line pipe is enough
With moving ahead, keyholed back plate pushes away that capsule is through to be connected through suction and conveying pipe, described retrogressing pipe foot keyholed back plate pushes away the through company of capsule through suction and conveying pipe and retrogressing
Connecing, the data wire of described photographic head and flash lamp stretches out from operation capsule successively after inwall and suction and conveying pipe pass, described suction bags
Being provided with drain pipe to stretch out from operation capsule, described gas tube passes the through connection of suction and conveying Guan Houyu gas cell.
It is connected flexible connection by bulb between described dynamic suction ball and suction and conveying pipe.
Described scrape line taking and have four row, each column four.
Distance between described inwall and outer wall is 0.1～0.4 millimeter.
Described moving ahead pushes away capsule and retrogressing pushes away and is designed with on capsule pushing away capsule pipe, described in push away capsule pipe and stretch out from operation capsule.
The invention has the beneficial effects as follows:
The present invention utilizes and scrapes the pliability of line taking and certain the most extending, at the intestinal that absorption rearward projection is tight after tightening
Inner surface scrapes, and reaches not only to can ensure that the purpose do not killed experimental rat but also be obtained in that intestinal inner surface cell.It makes
Simply, workable, with low cost, effect is obvious.
(4) accompanying drawing explanation
The present invention is further illustrated below in conjunction with the accompanying drawings.
Fig. 1 is the main TV structure schematic diagram of the present invention；
Fig. 2 is to inhale the sectional structure schematic diagram of ball portion；
Fig. 3 is front line pipe foot and the perspective view retreating pipe foot；
Fig. 4 is the cross section structure schematic diagram of the dynamic suction bulb in using.
In figure, 1 dynamic ball of inhaling, 2 suction and conveying pipes, 3 operation capsules, 4 bulbs connect, 5 outer walls, 6 inwalls, 7 inflation cabins, and 8 stretch cabin, and 9
Dynamic ball neck of inhaling, 10 dynamic suction bulbs, 11 pipette, 12 photographic head, 13 flash lamies, 14 data wires, 15 scrape line taking, line pipe foot before 16,
17 retreat pipe foot, 18 pipe foot walls, 19 pipe volas, and 20 control film, 201 cracks, 21 ring cake support rings, cake at the bottom of 22 suckers, 23 ring cakes
Connecting rod, 24 suspensions, 25 pipe foot pipes, line pipe toe ring pipe before 26, line pipe foot keyholed back plate before 27,28 retreat pipe toe ring pipe, and 29 retreat pipe foot
Keyholed back plate, 30 gas tubes, 31 move ahead pushes away capsule, 32 suction bags, 33 gas cells, and 34 retrogressings push away capsule, 35 drain pipes, and 36 push away capsule pipe, 37 pipes
Pedal aperture.
(5) detailed description of the invention
Accompanying drawing is the specific embodiment of the present invention.As shown in Figures 1 to 4, this kind of experiment made on the living intestine in rats tapetum cell
Scraping device, including dynamic suction ball 1, suction and conveying pipe 2 and the operation capsule 3 of the olive-type being sequentially connected with, between dynamic suction ball 1 and suction and conveying pipe 2
4 flexible connections are connected, wherein by bulb:
Bulb connects 4 valve cocks being analogous to tire: have a stainless steel tube on dynamic suction ball 1, its root band outside nut,
Suction and conveying pipe 2 is inserted on stainless steel tube, then tightens with fastening nut；Dynamic ball 1 of inhaling is followed successively by the outer wall of silica gel material from outside to inside
5, the inwall 6 of stainless steel and inflation cabin 7, outer wall 5 thickness is 0.1～0.3 millimeter, and the pliability of silica gel can ensure that dynamic suction
Intestinal epidermis is not damaged when ball 1 is walked in intestine in rats, after coating lubricating fluid simultaneously, also allows for dynamic ball 1 of inhaling and walk,
Inwall 6 thickness is 0.1～0.5 millimeter, and inwall 6 is hollow structure, and the two ends of outer wall 5 and inwall 6 are joined together to form flexible
Cabin 8, the thickness in flexible cabin 8 is namely 0.1～0.4 millimeter from inwall 6 to the distance of outer wall 5, and inflation is filled with air in cabin 7,
Inwall 6 front end is sequentially connected with the dynamic suction ball neck 9 being made up of pellosil and dynamic suction bulb 10, dynamic suction ball neck 9 and dynamic suction bulb 10 all
Truncated cone-shaped and their go to the bottom for hollow link together, and the dynamic pipette 11 inhaling ball neck 9 connection passes from inflation cabin 7,
The dynamic end inhaling bulb 10 is uniformly provided with 1-4 photographic head 12 and 1-12 flash lamp 13, these photographic head 12 and flash lamp 13
Data wire 14 pass from the cavity of inwall 6, it is nonelastic that the inner surface at dynamic suction bulb 10 is provided with that four row radially distribute
Scrape line taking 15, each column four scrapes line taking 15, scrapes the two ends of line taking 15 and is fixed on dynamic suction on bulb 10 inwall, scrapes line taking 15 general
Employing cotton thread；At 1/10～3/10 that front end is counted, line pipe foot 16 before 2～5 circles, inwall it is provided with on the outer surface of inwall 6
Being provided with 2～5 on the outer surface of 6 at 1/10～3/10 that rear end is counted and enclose retrogressing pipes foot 17, front line pipe foot 16 is sufficient with retrogressing pipe
The structure of 17 is identical, and their top is all located in the pipe pedal aperture 37 on outer wall 5, their a diameter of 0.01～0.5 millimeter, long
Degree is 0.1～2 millimeter, and their structure is: by having the cylindric pipe foot wall 18 that resilient silica gel is made, pipe foot wall 18 energy
Flexible, its inner chamber can fill the warm water of 36.8～37.2 DEG C, for the thicker pipe vola 19 being made up of pellosil bottom pipe foot wall 18,
Pipe vola 19 sticks on inwall 6 outer surface, be provided with in pipe foot wall 18 have a crack 201 control film 20 and rustless steel quality
Ring cake support ring 21, control film 20 is close to pipe vola 19, and ring cake support ring 21, away from pipe vola 19, controls film 20 and pipe foot wall 18
Axis perpendicular and its periphery be connected with pipe foot wall 18 inwall 6, pipe foot wall 18 upper end is provided with cake 22 at the bottom of sucker, cake 22 at the bottom of sucker
Being connected by three ring cake connecting rods 23 and ring cake support ring 21, the angle between adjacent two ring cake connecting rods 23 is 120 °, sucker
Connecting between end cake 22 and pipe vola 19 and have inelastic suspension 24, the length of suspension 24 is less than the height of pipe foot wall 18, due to
Pullling of suspension 24, the top of pipe foot wall 18 presents the shape of indent, namely sucker, be positioned at pipe vola 19 and control film 20 it
Between pipe foot wall 18 on connect and have a pipe foot pipe 25, pipe foot pipe 25 on front line pipe foot 16 is through with front line pipe toe ring pipe 26 to be connected,
Front line pipe toe ring pipe 26 is provided with front line pipe foot keyholed back plate 27, the pipe foot pipe 25 on all retrogressing pipes foot 17 and retrogressing pipe toe ring pipe 28
Through connection, retreats pipe toe ring pipe 28 and is provided with retrogressing pipe foot keyholed back plate 29；As in figure 2 it is shown, front line pipe toe ring pipe 26 and retrogressing pipe
Toe ring pipe 28 is all located between all front line pipes foot 16 and all retrogressing pipes foot 17；When warm water enters pipe foot wall 18 from pipe foot pipe 25
Inner chamber time, warm water is after crack 201 enters the top of pipe foot wall 18, owing to having the restriction of inelastic suspension 24, at the bottom of sucker
Distance between cake 22 and pipe vola 19 is constant, but owing to pipe foot wall 18 is flexible, therefore under the impact of warm water, at pipe foot wall
The top of 18 is the formation of sucker, and crack 201 can be that warm water provides temporary transient backflow resistance simultaneously, in order to preferably forms pipe
The sucker on foot wall 18 top；
Inflation cabin 7 connects gas tube 30；On the one hand the effect in inflation cabin 7 is can be by pipette 11 in dynamic suction ball 1
Diameter pressure little, it is simple on the other hand suction bags 32 operates, and is when the liquid volume drawn is bigger, it is provided that one is available for delaying
The space of punching, then to have be exactly when, after inflation cabin 7 gassy, dynamic suction bulb 10 being released inflation cabin 7；
Suction and conveying pipe 2 is to connect the dynamic cylindrical conduit inhaling ball 1 and operation capsule 3, and external diameter is 0.2～2 millimeter, its outer wall 5 silicon
Colloid, thick 0.05～0.1 millimeter, operation capsule 3 is the bladder made by rubber, and olive shape, wall thickness 1～3 millimeters, before being inside provided with
Row pushes away capsule 31, suction bags 32, gas cell 33 and retrogressing and pushes away capsule 34, and pipette 11 sequentially passes through inflation cabin 7 and suction and conveying pipe 2 and draws
Capsule 32 connects, and with moving ahead, front line pipe foot keyholed back plate 27 pushes away that capsule 31 is through to be connected through suction and conveying pipe 2, retreat pipe foot keyholed back plate 29 through suction and conveying
Pipe 2 pushes away with retrogressing that capsule 34 is through to be connected, and the data wire 14 of photographic head 12 and flash lamp 13 passes from inwall 6 and suction and conveying pipe 2 successively
After from operation capsule 3 stretch out, suction bags 32 be provided with drain pipe 35 from operation capsule 3 stretch out.Move ahead and push away capsule 31 and retrogressing pushes away on capsule 34
It is designed with pushing away capsule pipe 36, pushes away capsule pipe 36 and stretch out from operation capsule 3, be used for adding or discharging warm water；Gas tube 30 is worn from suction and conveying pipe 2
Later through with gas cell 33 it is connected.
Work process is as follows: first will move ahead pushes away capsule 31 and retrogressing pushes away capsule 34 and fills warm water, photographic head 12 and flash lamp 13
Data wire 14 be connected with computer, observed by computer and dynamic inhale the ball 1 position in intestinal, it is simple to operation；The present invention is inserted
The intestinal of rat, operation moves ahead and pushes away capsule 31, after having before being distributed of front line pipe foot 16, line pipe foot 16 before therefore warm water is full of
Time just have and first have after, be introduced into the front line pipe foot 16 pushed away close to capsule 31 from moving ahead, then sequentially enter push away from moving ahead capsule 31 with away from
Front line pipe foot 16, have a time difference among these, and owing to pipe foot wall 18 is for having what resilient silica gel was made, also have outstanding
The tractive of silk 24, therefore the top of front line pipe foot 16 successively forms sucker and stretches out absorption at intestine in rats inwall from pipe pedal aperture 37
On 6, provide power forward for dynamic suction ball 1, drive dynamic ball 1 of inhaling to travel forward (principle that moves ahead duplicates in Asterias amurensis Lutken), pass through computer
The dynamic position inhaling ball 1 of observation also operates, and when arriving precalculated position, dynamic suction bulb 10 vertically bends towards intestinal due to the reason of gravity
Road inwall 6, now operation suction bags 32, the tissue of intestinal inner surface is attracted to inside thing head, as shown in Figure 4, now due to
Scraping line taking 15 and do not have elasticity, and dynamic bulb 10 of inhaling is flexible, dynamic bulb 10 of inhaling is heaved, it appears that be equivalent to the string one of a circle
Sample so that scraping line taking 15 and form toughness scraper one by one in dynamic suction bulb 10, meanwhile, intestinal wall inner surface is made due to suction
With and be attracted to the dynamic inner chamber inhaling bulb, during the two is mutually shifted, in the case of not injuring intestinal inside, scrape line taking
Just intestinal tapetum cell is scraped down, external by pipette 11 sucking-off；Draw complete, move back after the activation and push away capsule 34 by dynamic suction
Ball 1 exits intestine in rats, and process is contrary with when moving ahead, near after warm water is the most remote, does not repeats them here；The cell will drawn after exiting
Tissue is released from drain pipe 35, and whole operation just completes.
In addition to technical characteristic described in description, remaining technical characteristic is all known to a person skilled in the art technology.
Claims (5)
1. an experiment made on the living intestine in rats tapetum cell scraping device, is characterized in that: include moving of the olive-type being sequentially connected with
Inhaling ball (1), suction and conveying pipe (2) and operate capsule (3), described dynamic suction ball (1) is followed successively by the outer wall (5), no of silica gel material from outside to inside
The inwall (6) of rust steel matter and inflation cabin (7), the two ends of described outer wall (5) and inwall (6) are joined together to form flexible cabin
(8), described inwall (6) front end is sequentially connected with dynamic suction ball neck (9) being made up of pellosil and dynamic suction bulb (10), described dynamic suction ball
Neck (9) and dynamic inhale truncated cone-shaped that bulb (10) is all hollow and their go to the bottom links together, described dynamic suction bulb (10)
End be provided with at least one photographic head (12) and at least one flash lamp (13), described dynamic suction bulb (10) inner surface is provided with number
What row radially distributed nonelastic scrapes line taking (15)；Count from front end the 1/10～3/10 of the outer surface of described inwall (6)
Place be provided with 2～5 circle before line pipes foot (16), the outer surface of described inwall (6) be provided with at 1/10～3/10 that rear end is counted 2～
5 circles retreat pipe foot (17), and the top of described front line pipe foot (16) and retrogressing pipe foot (17) is all located at the pipe pedal aperture on outer wall (5)
(37), in, described front line pipe foot (16) is identical with retreating pipe foot (17) structure, and they all include: have what resilient silica gel was made
Cylindric pipe foot wall (18), pipe foot wall (18) bottom is the pipe vola (19) being made up of pellosil, and described pipe vola (19) is glued
It is attached on inwall (6) outer surface, in described pipe foot wall (18), is provided with the control film (20) having crack (201), described control film
(20) periphery is connected with pipe foot wall (18) inwall, and described pipe foot wall (18) upper end is provided with cake at the bottom of sucker (22), cake at the bottom of described sucker
(22) it is connected with pipe foot wall (18) inwall by ring cake connecting rod (23) and ring cake support ring (21), cake (22) at the bottom of described sucker and pipe
Connecting between vola (19) and have inelastic suspension (24), the length of described suspension (24) is less than the height of pipe foot wall (18), position
Pipe foot pipe (25) is had, in all front line pipes foot (16) in pipe vola (19) and the upper connection of pipe foot wall (18) controlled between film (20)
Pipe foot pipe (25) are through with front line pipe toe ring pipe (26) is connected, described front line pipe toe ring pipe (26) is provided with front line pipe foot keyholed back plate
(27), the sufficient pipe (25) of the pipe on all retrogressing pipes foot (17) is through with retrogressing pipe toe ring pipe (28) to be connected, described retrogressing pipe toe ring
Pipe (28) is provided with retrogressing pipe foot keyholed back plate (29)；Described front line pipe toe ring pipe (26) and retrogressing pipe toe ring pipe (28) are positioned at front line pipe
Between foot (16) and retrogressing pipe foot (17)；Described inflation cabin (7) connects gas tube (30)；Before being provided with in described operation capsule (3)
Row pushes away capsule (31), suction bags (32), gas cell (33) and retrogressing and pushes away capsule (34), and described dynamic suction ball neck (9) connects pipette
(11), described pipette (11) sequentially passes through inflation cabin (7) and suction and conveying pipe (2) is through with suction bags (32) is connected, described in move ahead
With moving ahead, pipe foot keyholed back plate (27) pushes away that capsule (31) is through to be connected through suction and conveying pipe (2), described retrogressing pipe foot keyholed back plate (29) passes suction and conveying
Pipe (2) pushes away with retrogressing that capsule (34) is through to be connected, and the data wire (14) of described photographic head (12) and flash lamp (13) is successively from inwall
(6) and suction and conveying pipe (2) pass after from operation capsule (3) stretch out, described suction bags (32) be provided with drain pipe (35) from operation capsule (3)
Stretching out, described gas tube (30) is connected through suction and conveying pipe (2) is through with gas cell (33) afterwards.
Experiment made on the living intestine in rats tapetum cell scraping device the most according to claim 1, is characterized in that, described dynamic suction ball
(1) it is connected (4) flexible connection with between suction and conveying pipe (2) by bulb.
Experiment made on the living intestine in rats tapetum cell scraping device the most according to claim 1, is characterized in that, described in scrape line taking
(15) there are four row, each column four.
Experiment made on the living intestine in rats tapetum cell scraping device the most according to claim 1, is characterized in that, described inwall
(6) distance and between outer wall (5) is 0.1～0.4 millimeter.
5., according to the experiment made on the living intestine in rats tapetum cell scraping device described in any one of Claims 1-4, it is characterized in that,
Described moving ahead pushes away capsule (31) and retrogressing pushes away and is designed with on capsule (34) pushing away capsule pipe (36), described in push away capsule pipe (36) from operation capsule (3)
Stretch out.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510068325.8A CN104644224B (en) | 2015-02-10 | 2015-02-10 | In-vivo experimental mouse intestinal canal inner wall cell scraping device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510068325.8A CN104644224B (en) | 2015-02-10 | 2015-02-10 | In-vivo experimental mouse intestinal canal inner wall cell scraping device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104644224A CN104644224A (en) | 2015-05-27 |
| CN104644224B true CN104644224B (en) | 2017-01-11 |
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| CN201510068325.8A Expired - Fee Related CN104644224B (en) | 2015-02-10 | 2015-02-10 | In-vivo experimental mouse intestinal canal inner wall cell scraping device |
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113116397B (en) * | 2019-12-30 | 2023-02-28 | 上海科罡医疗技术有限公司 | Esophageal wall cell sampler |
| CN114209362B (en) * | 2022-01-27 | 2022-12-13 | 湖南港湾科学仪器有限公司 | Gastric juice and esophagus cell collector in stomach |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2624817Y (en) * | 2003-07-19 | 2004-07-14 | 黄长征 | Self-examining equipment for human body cavities |
| GB0415277D0 (en) * | 2004-07-07 | 2004-08-11 | Colonix Ltd | Apparatus and method for sampling mucosal surfaces |
| US20070293720A1 (en) * | 2005-01-05 | 2007-12-20 | Avantis Medical Systems, Inc. | Endoscope assembly and method of viewing an area inside a cavity |
| US20060200043A1 (en) * | 2005-03-01 | 2006-09-07 | Jannetty Joseph D | Pap smear collection device with ejection sleeve |
| EP2417914B1 (en) * | 2006-01-12 | 2014-06-11 | Multi Biopsy Instruments ApS | An apparatus for taking tissue samples |
| GB201304738D0 (en) * | 2013-03-15 | 2013-05-01 | Mars Inc | Sampling Device |
| CN203898360U (en) * | 2014-06-16 | 2014-10-29 | 重庆医科大学附属永川医院 | Device for elastically taking out sample under laparoscope |
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