CN104634821A - RFID based bio sensor measurement device and measuring method using thereof - Google Patents
RFID based bio sensor measurement device and measuring method using thereof Download PDFInfo
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- CN104634821A CN104634821A CN201410443118.1A CN201410443118A CN104634821A CN 104634821 A CN104634821 A CN 104634821A CN 201410443118 A CN201410443118 A CN 201410443118A CN 104634821 A CN104634821 A CN 104634821A
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Abstract
The present invention relates to an RFID-based bio sensor measurement device and a measurement method using same allowing element measurement in conjunction with a wireless communication device such as a smart phone. The NFC or RFID-based bio sensor measurement device according to the present invention includes a bio sensor portion (100) where a reaction reagent is embedded; and an NFC or RFID portion (200) that is electrically connected to the bio sensor portion (100), wirelessly receives electric power from an external electronic device, and measures a measurement target value by using the bio sensor portion (100) and then wirelessly transmits the result to the external electronic device. With the NFC or RFID-based bio sensor measurement device according to the present invention, no additional measuring device has to be purchased and strips can be purchased one by one for economic advantages. Also, the present invention uses a portable smart device which is a personal necessity of modern people, and thus blood sugar, anemia, blood coagulation time, and the like can be diagnosed on the site even in the absence of a measuring system during a trip or the like.
Description
Technical field
The present invention relates to the biology sensor measurement mechanism based on wireless near field communication and measuring method thereof, in more detail, utilize and can carry out the device of wireless near field communication and the intelligent apparatus such as smart mobile phone, panel computer and the electrochemistry sensor surveying unit of the biological component such as the blood of monitoring human or animal or body fluid and measuring method thereof.
Background technology
At present, the eating habit because of modern is tending towards westernization, and the people suffering from the so-called adult disease such as diabetes, hyperlipidemia, thrombosis patients increases gradually, and the situation of young woman causes the patient of hypoferric anemia to increase severely.The weight whether straightforward procedure that can confirm this adult disease is exactly measure the biological component in blood.By the measurement of biological component, can know the content of the Multiple components that the blood such as blood sugar, anaemia, blood clotting comprises, ordinary people Bu Qu hospital just easily can judge that the numerical value of special component belongs to normal range or non-normal range etc.
Measuring one of short-cut method of biological component is exactly utilize electrochemistry disposable biological sensor, after the blood taked from finger tip is injected lengthy motion picture, utilize electrochemistry or photometry and quantitative test output signal, this method just can show corresponding component content on surveying instrument, is therefore applicable to very much the ordinary people without professional knowledge.
Traditional electrochemistry biology sensor is ' open in patent documentation 1 '.Fig. 1 illustrates traditional electrochemistry biology sensor, and traditional electrochemistry biology sensor 1 comprises: lower plate 5, has operation electrode 2, reference electrode 3 and corpse or other object for laboratory examination and chemical testing identification electrode 4; Middle plate 7, forms a corpse or other object for laboratory examination and chemical testing and inserts stream 6 and be layered in lower plate 5; Upper plate 8, is layered on middle plate 7.Operation electrode 2, the splicing ear 9 of reference electrode 3 and corpse or other object for laboratory examination and chemical testing identification electrode 4 is inserted into measuring instrument, as illustrated in Figure 2, measuring instrument shows the special component of blood.
But this traditional electrochemistry biology sensor need buy measuring instrument separately because of user, Problems existing point be burden economically and go on business, the migration such as tourism when also to carry measuring instrument.
Patent documentation
(patent documentation 0001) KR10-1003077B1 (2010.12.21)
Summary of the invention
(technical matters that will solve)
The present invention proposes to solve described problem points, the technical problem to be solved in the present invention is to provide a kind of biology sensor measurement mechanism based on wireless near field communication and measuring method thereof, without the need to other measuring instrument, utilize internal short-range radio communication [NFC; Near Field CommunIcation or RFID; Radio-Frequency IdentifIcation] intelligent apparatus of function just can diagnose the numerical value of biological component.
(means of dealing with problems)
For solve the technical problem according to the biology sensor measurement mechanism based on wireless near field communication of the present invention, it is characterized in that, comprising: biology sensor portion, built-in reaction reagent; And wireless near field communication portion, being connected with described biology sensor portion electrical resistance, from external electronic with wireless receiving electric power, utilizing described biology sensor portion to measure measuring object value by being wirelessly transmitted to external electronic.
Utilize the measuring method according to the biology sensor measurement mechanism based on wireless near field communication of the present invention, it is characterized in that, comprising: make external electronic near the close step of the described biology sensor measurement mechanism based on wireless near field communication; The measurement that described external electronic performs initiation command starts step; Described external electronic also transmits the order transfer step of order to the described supply of the biology sensor measurement mechanism based on wireless near field communication electric power; Receive order by the described biology sensor measurement mechanism based on wireless near field communication and generate the electric power generation step of electric power; The described biology sensor measurement mechanism recognition command based on wireless near field communication also applies voltage or electric current to sensor and obtains the command recognition step of signal; Simulating signal is transformed into the signal shift step of digital signal by the described biology sensor measurement mechanism based on wireless near field communication; Converted signal is saved in storer or is sent to preservation and the transfer step of described external electronic by the described biology sensor measurement mechanism based on wireless near field communication; Described external electronic receives converted signal and the reception utilizing built-in application program to carry out showing and step display; And the end step of the NFC function of closedown (off) described external electronic.
(effect of invention)
According to the biology sensor measurement mechanism based on wireless near field communication of the present invention, without the need to buying measuring instrument in addition, can buy separately a lengthy motion picture, economy is very outstanding.Further, make use of the individual necessity of modern and portable intelligent apparatus, when therefore not carrying measuring instrument during the journey because of error, also can field diagnostic blood sugar, anaemia, blood coagulation time etc.
Accompanying drawing explanation
Fig. 1 is the exploded perspective view of traditional electrochemistry biology sensor.
Fig. 2 is the measuring instrument being attached to traditional electrochemistry biology sensor.
Fig. 3 is the concept map according to the bio-sensing based on wireless near field communication of the present invention.
Fig. 4 is the stereographic map according to the biology sensor measurement mechanism based on wireless near field communication of the present invention.
Fig. 5 is the cut-away view according to the biology sensor measurement mechanism based on wireless near field communication of the present invention.
Fig. 6 is the structural drawing according to RF interface of the present invention.
Fig. 7 be possess measurement processor according to the biology sensor measurement mechanism based on wireless near field communication of the present invention.
Fig. 8 and Fig. 9 is another example according to the biology sensor measurement mechanism based on wireless near field communication of the present invention.
Figure 10 is the using state figure utilizing reader or intelligent apparatus.
Figure 11 utilizes the process flow diagram according to the measuring method of the biology sensor measurement mechanism based on wireless near field communication of the present invention.
(description of reference numerals)
100: biology sensor portion 200: wireless near field communication portion
210:A/D converter 220: antenna
230:RF interface 231: signal modem
233: rectifier 235: signal inductor
237: voltage stabilizer 239: clock generator
240: control module 250: signal amplifier
260: signal converter 270: storer
280: correction purpose processor 290: measurement processor
Embodiment
Below, describe in detail according to the biology sensor measurement mechanism based on wireless near field communication of the present invention and measuring method thereof with reference to accompanying drawing.
Fig. 3 is the concept map according to the bio-sensing based on wireless near field communication of the present invention, Fig. 4 is the stereographic map according to the biology sensor measurement mechanism based on wireless near field communication of the present invention, and Fig. 5 is the cut-away view according to the biology sensor measurement mechanism based on wireless near field communication of the present invention.
As illustrated in fig. 3, based in the biology sensor measurement mechanism 100 of wireless near field communication, display measurement value in the personal intelligent apparatus 200 that can have most people, therefore without the need to buying measuring instrument in addition for basic fundamental thought of the present invention.Pass through the modes such as NFC or RFID according to the biology sensor measurement mechanism based on wireless near field communication of the present invention with the electric power of the supply of wireless receiving external electronic, can transmit and receive data and order, without the need to other battery.
According to the biology sensor measurement mechanism 100 based on wireless near field communication of the present invention, comprising: biology sensor portion 100, built-in reaction reagent, this material such as reaction reagent and blood produces reaction and changes its physical property; And wireless near field communication portion 200, being connected with described biology sensor portion 100 electrical resistance, from external electronic with wireless receiving electric power, utilizing described biology sensor portion 100 to measure measuring object value and by being wirelessly transmitted to external electronic.The applicable intelligent apparatus of external electronic or reader etc., preferably, popularity rate is high and be easy to carry, and can arrange the intelligent apparatus be applicable to according to the application program of the biology sensor measurement mechanism based on wireless near field communication of the present invention.
Biology sensor portion 100 makes sample produce reaction and measures the inscape of the electrochemical properties change of sample, biology sensor portion 100 internal fixtion optionally with Organism Samples aitiogenic reaction reagent, such as ferment, specific polymer substance etc., therefore, it is possible to measure physical signalling or chemical signal.
Built-inly in biology sensor portion 100 suitably to select, can reaction reagent aitiogenic with various index components, for measuring blood sugar, measure anaemia, measure blood coagulation time etc.
The structure of general biology sensor is a pair potential electrode or additional samples identification electrode (in potential electrode used as being 1 during common electrode, except be a pair of), and therefore the electrode terminal in biology sensor portion 100 has 2 ~ 4.
Wireless near field communication portion 200 be connected with biology sensor portion 100 electrical resistance and perform the measurement of measuring object value, data processing, with the data transmission of external electronic and reception, the inscape receiving the functions such as electric power from external electronic, it comprises: A/D converter 210, and the simulating signal that biology sensor portion 100 transmits is transformed into digital signal; Antenna 220, carries out transmission and the reception of data and electric power with external electronic; RF interface 230, the data that induction or modulation /demodulation are received from described external electronic by antenna 220 or control signal; And control module 240, process the order (utilizing the order of wireless near field communication) transmitted from described external electronic.
Further, wireless near field communication portion 200 also can comprise: signal amplifier 250, increases the size of the signal received from biology sensor portion 100; Signal converter 260, makes the signal received from biology sensor portion 100 be transformed into the signal of applicable control module 240 process; Storer 270, can programme and can eliminate in electrical resistance ground; Correction purpose processor 280, for the correction of signal; Measurement processor 290, measures measuring object value by the signal received from biology sensor portion 100.
A/D converter 210 is inscapes simulating signal being transformed into digital signal, is connected to biology sensor portion 100, the simulating signal transmitted is transformed into digital signal and is provided to control module 240 from biology sensor portion 100.
Antenna 220 is inscapes that the transmission can carrying out data and electric power with external electronic such as intelligent apparatus receives, and as illustrated in figure 4, has prescribed model.The concrete specification (lines amplitude, pattern etc.) of antenna 220 according to the frequency of wireless near field communication, arrive distance, energy conveying capacity hourly etc. and different, this is the design item of those skilled in the art, according to circumstances carries out suitable design and uses.
Fig. 6 is the structural drawing according to RF interface of the present invention.
RF interface 230 responds to by antenna 220 signal that receives and carries out the inscape of modulation /demodulation, is connected to antenna 220 and comprises signal modem 231 and rectifier 233.
The signal madulation comprising measurement data, in order to the data of measurement are sent to external electronic, is become to be applicable to the waveform transmitted by signal modem 231, the signal receiving received is become to be applicable to the waveform that control module 240 processes from external electronic.The signal be modulated into according to multiple band domain of current wireless near field communication standard is sent to antenna 220.
Rectifier 233 receives electric power from external electronic and generates the electric power of the driving for signal modem 231, control module 240 etc.
The signal that the external electronic that received by antenna 220 of responding to signal inductor 235 is transmitted also is sent to signal modem 231 or control module 240.By signal modem 231 and signal inductor 235, realize according to the wireless near field communication between the biology sensor measurement mechanism based on wireless near field communication of the present invention and external electronic.
Further, RF interface 230 also comprises voltage stabilizer 237, and the electric adjustment generated by rectifier 233 is required voltage; Clock generator 239, generated clock; Thus rectification can be carried out to signal and generated clock and be fed to control module 240.Electric power generating unit is formed by rectifier 233 and voltage stabilizer 237 in most of device.
The frequency band domain of current standardized NFC is 13.56MHz, transport maximum distance is within 20 ㎝, generally use within 10 ㎝, therefore external electronic will be made close according to the biology sensor measurement mechanism based on wireless near field communication of the present invention (during RFID, frequency band domain or running distance can be different).Make external electronic when sensor surveying unit, external electronic produces electromagnetic induction phenomenon to antenna 220, and rectifier 233 utilizes voltage stabilizer and suitably converts electric power that this electromagnetic induction transmits and be fed to inner element.
Control module 240 identifies and processes the inscape of the order received from the external electronic of outside, is connected and identified the order received from external electronic by antenna 220, apply curtage to biology sensor portion 100 with RF interface 230.Biology sensor measurement mechanism based on wireless near field communication according to the present invention is type hand, therefore utilizes the electric power that rectifier 233 generates.
Signal amplifier 250 is the inscapes of signal magnitude being carried out to amplification, during the weak output signal transmitted by biology sensor portion 100, carries out amplification and make signal transacting become easy to this.When the signal magnitude that is functional or that transmitted by biology sensor portion 100 of control module 240 is fully large, signal amplifier can be omitted.
Signal converter 260 is the inscapes signal transmitted by biology sensor portion 100 being transformed into the signal that applicable control module 240 processes, and such as, changes ER effect into voltage.Usually, electronic component take magnitude of voltage as input, the IC (integrated circuit) such as current value is transformed into the signal converter 260 of magnitude of voltage by general, such as OPAMP (operational amplifier).When being designed to can process current value according to the element of the biology sensor measurement mechanism inside based on wireless near field communication of the present invention, signal converter 260 can be omitted.That is, when being inputted as sensor by current value, result can obtain magnitude of voltage, therefore, it is possible to omit signal converter 260.
Storer 270 is the inscapes of the data of preserving handled by control module 240, it is connected to control module 240, preferred use can the programming of electrical resistance ground and eliminable EEPROM (Electrically Erasable and Programmable Read Only Memory, electricallyerasable ROM (EEROM)).EEPROM does not have power supply can the nonvolatile memory of long-time stable record yet, the data of record and record is again eliminated by distortion electrical resistance ground by the EPROM (Erasable and Programmable Read Only Memory, EPROM (Erasable Programmable Read Only Memory)) that can eliminate and programme.Utilize this EEPROM and the data of preserving handled by control module 240, or be sent to external electronic without the need to the process of preserving.During without the need to preserving the data handled by control module 240, storer 270 can be omitted.
Also can comprise correction purpose processor 280, correction purpose processor 280 is the inscapes of the data measured by biology sensor portion 100 in the digital signal that transmitted by A/D converter 210 of correction, it is connected to A/D converter 210 and data measured by correction biology sensor portion 100, and the data of correction are sent to control module 240.If utilize correction purpose processor 280, power consumption can increase, but can data by more accurate correct calculation measured by correction biology sensor portion 100.This data correcting function can be designed to be processed by control module 240.
As required, also measurement processor can be comprised.Fig. 7 be possess measurement processor according to the biology sensor measurement mechanism based on wireless near field communication of the present invention.Measurement processor 290 utilizes conventional General N FC label chip and presents according to the necessary inscape during biology sensor measurement mechanism based on wireless near field communication of the present invention, general NFC label chip only participates in NFC communication, the measuring object values such as blood sugar amount cannot be extracted from the signal measured by biology sensor portion 100, therefore in order to know measuring object value, measurement processor 290 is needed.Measurement processor 290 is from A/D converter 210 Received signal strength (when having correction purpose processor, receiving the signal of correction from correction purpose processor) and be sent to control module 240 after measuring measuring object value.
Fig. 8 and Fig. 9 is another example according to the biology sensor measurement mechanism based on wireless near field communication of the present invention.Illustrated in Fig. 8 (a), RF interface 230 and control module 240 can be formed by NFC label chip, or illustrated in Fig. 8 (b), RF interface 230, control module 240 and storer 270 can be formed by NFC label chip.And, as illustrated in fig. 9, formed and comprise RF interface 230 and the NFC core of control module 240, NFC core is formed with SoC (System on Chip, SOC (system on a chip)) form in conjunction with the NFC label chip of A/D converter 210, signal amplifier 250, signal converter 260.
Figure 10 is the using state figure utilizing reader or intelligent apparatus.Illustrated in Figure 10 (a), by reader display measurement value, or illustrated in Figure 10 (b), by intelligent apparatus display measurement value.
The smart mobile phone, PDA, panel computer, notebook etc. of the preferred built-in NFC/RFID function of intelligent apparatus.
Reader is built-in NFC/RFID function and communicates with the biology sensor measurement mechanism based on wireless near field communication according to the present invention, the device of the data that (Read) measures can be read, do not use the user of intelligent apparatus without the need to reader.
Secondly, the measuring method utilized according to the biology sensor measurement mechanism based on wireless near field communication of the present invention is described.Figure 11 utilizes the process flow diagram according to the measuring method of the biology sensor measurement mechanism based on wireless near field communication of the present invention.
1. near step (S10): make external electronic close according to the biology sensor measurement mechanism based on wireless near field communication of the present invention.
2. measure and start step (S20): in external electronic, perform the step that beginning (Start) is ordered, such as, perform beginning (Start) order by the application program being arranged on intelligent apparatus, or the button pressing reader performs.
3. order transfer step (S30): external electronic is supplied electric power to the biology sensor measurement mechanism based on wireless near field communication according to the present invention and transmitted order.
4. electric power generation step (S40): receive order according to the biology sensor measurement mechanism based on wireless near field communication of the present invention by antenna 220, rectifier 233 generates electric power.
5. command recognition step (S50): control module 240 recognition command, applies voltage or electric current and obtains signal to biology sensor portion 100.
6. signal shift step (S60): simulating signal is transformed into digital signal by A/D converter 210.
7. preserve and transfer step (S70): the signal of conversion be saved in storer 270 or be sent to described external electronic by antenna 220.
8. receive and step display (S80): described external electronic receives the signal of conversion and utilizes built-in application program to show.
9. end step (S90): close the NFC function of (off) external electronic and interrupt electric power supply, terminates the measurement in biology sensor portion 100.
Measurement starts step (S20) and order transfer step (S30) can perform before sensor Connection Step (S10).That is, externally electronic installation, before the biology sensor measurement mechanism logical based near radio according to the present invention, performs beginning (Start) order by external electronic.
Claims (12)
1., based on a biology sensor measurement mechanism for wireless near field communication, it is characterized in that, comprising:
Biology sensor portion, built-in reaction reagent; And
Wireless near field communication portion, is connected with described biology sensor portion electrical resistance, from external electronic with wireless receiving electric power, utilizes described biology sensor portion to measure measuring object value by being wirelessly transmitted to external electronic.
2. the biology sensor measurement mechanism based on wireless near field communication according to claim 1, is characterized in that, comprising:
Described biology sensor portion can carry out the measurement of physical signalling or chemical signal.
3. the biology sensor measurement mechanism based on wireless near field communication according to claim 1, is characterized in that, comprising:
Described wireless near field communication portion and described external electronic are carried out NFC or RFID and are communicated.
4. the biology sensor measurement mechanism based on wireless near field communication according to claim 1, is characterized in that, comprising:
Described external electronic is at least one in reader, smart mobile phone, PDA, panel computer, notebook.
5. the biology sensor measurement mechanism based on wireless near field communication according to claim 1, is characterized in that,
Described wireless near field communication portion, comprising:
A/D converter, is connected to described biology sensor portion and the simulating signal that described biology sensor portion transmits is transformed into digital signal;
Antenna, carries out transmission and the reception of data and electric power with described external electronic;
RF interface, the data that induction or modulation /demodulation are received from described external electronic by described antenna or control signal; And
Control module, processes the order transmitted from described external electronic.
6. the biology sensor measurement mechanism based on wireless near field communication according to claim 5, is characterized in that, also comprise:
Measurement processor, receives the signal that transmits from described A/D converter and is sent to described control module after measuring measuring object value.
7. the biology sensor measurement mechanism based on wireless near field communication according to claim 5, is characterized in that:
Described RF interface and described control module are formed by NFC label chip.
8. the biology sensor measurement mechanism based on wireless near field communication according to claim 5, is characterized in that:
Form the NFC core comprising described RF interface and described control module, the NFC label chip that described NFC core is combined with A/D converter, signal amplifier, signal converter is formed with SoC (System on Chip) form.
9., based on a measuring method for the biology sensor measurement mechanism of wireless near field communication, it is characterized in that,
Make external electronic near the step of the biology sensor measurement mechanism based on wireless near field communication utilized according to any one in claim 1 to 8;
The measurement that described external electronic performs initiation command starts step;
Described external electronic also transmits the order transfer step of order to the described supply of the biology sensor measurement mechanism based on wireless near field communication electric power;
Receive order by the described biology sensor measurement mechanism based on wireless near field communication and generate the electric power generation step of electric power;
The described biology sensor measurement mechanism recognition command based on wireless near field communication also applies voltage or electric current to sensor and obtains the command recognition step of signal;
Simulating signal is transformed into the signal shift step of digital signal by the described biology sensor measurement mechanism based on wireless near field communication;
Converted signal is saved in storer or is sent to preservation and the transfer step of described external electronic by the described biology sensor measurement mechanism based on wireless near field communication;
Described external electronic receives converted signal and the reception utilizing built-in application program to carry out showing and step display.
10. utilization according to claim 9 is based on the measuring method of the biology sensor measurement mechanism of wireless near field communication, it is characterized in that:
The signal of described acquisition is physical signalling or chemical signal.
11. utilizations according to claim 9, based on the measuring method of the biology sensor measurement mechanism of wireless near field communication, is characterized in that:
Described order is transmitted by NFC or RFID communication and is received.
12. utilizations according to claim 9, based on the measuring method of the biology sensor measurement mechanism of wireless near field communication, is characterized in that:
Measuring object value is measured by described digital signal.
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| Application Number | Priority Date | Filing Date | Title |
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| KR10-2013-0137367 | 2013-11-13 | ||
| KR1020130137367A KR101518713B1 (en) | 2013-07-22 | 2013-11-13 | Nfc or rfid based bio sensor measurement device and measuring method using thereof |
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| CN105405842A (en) * | 2015-07-24 | 2016-03-16 | 香港应用科技研究院有限公司 | Self-powered and battery-assistant CMOS wireless biosensing IC platform |
| CN106970124A (en) * | 2017-02-24 | 2017-07-21 | 浙江大学 | It is a kind of based on mobile terminal for the NFC label sensing system of biochemistry detection and its application |
| WO2017210913A1 (en) * | 2016-06-08 | 2017-12-14 | 深圳精准医疗科技有限公司 | Wirelessly manageable reagent kit |
| CN108318560A (en) * | 2018-01-19 | 2018-07-24 | 国力天（深圳）科技有限公司 | A kind of Portable microelectrode method blood detector and its detection method |
| CN108366740A (en) * | 2016-08-08 | 2018-08-03 | 幸福软件有限公司 | Measure the portable complex sensor device and measurement method of multiple biological informations |
| WO2021082208A1 (en) * | 2019-10-29 | 2021-05-06 | 健蓝(上海)医疗科技有限公司 | Blood glucose monitoring device and system |
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| CN105405842A (en) * | 2015-07-24 | 2016-03-16 | 香港应用科技研究院有限公司 | Self-powered and battery-assistant CMOS wireless biosensing IC platform |
| CN105405842B (en) * | 2015-07-24 | 2018-11-20 | 香港应用科技研究院有限公司 | The wireless bio-sensing IC platform of CMOS of self-powered and battery auxiliary |
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| WO2021082208A1 (en) * | 2019-10-29 | 2021-05-06 | 健蓝(上海)医疗科技有限公司 | Blood glucose monitoring device and system |
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