CN104628612A - Nitrile benzenesulfonylhydrazine type GPR119 agonist, preparation method and application thereof - Google Patents
Nitrile benzenesulfonylhydrazine type GPR119 agonist, preparation method and application thereof Download PDFInfo
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- CN104628612A CN104628612A CN201510080394.0A CN201510080394A CN104628612A CN 104628612 A CN104628612 A CN 104628612A CN 201510080394 A CN201510080394 A CN 201510080394A CN 104628612 A CN104628612 A CN 104628612A
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Abstract
Description
Compound | EC 50(nM) |
Reference compound D-1 | 20.9 |
Compound I-1 | 9.4 |
Compound I-2 | 10.2 |
Compound I-3 | 10.7 |
Claims (4)
Priority Applications (1)
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CN201510080394.0A CN104628612B (en) | 2015-02-13 | 2015-02-13 | One class itrile group benzol sulfohydrazide class GPR119 agonist, preparation method and its usage |
Applications Claiming Priority (1)
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CN201510080394.0A CN104628612B (en) | 2015-02-13 | 2015-02-13 | One class itrile group benzol sulfohydrazide class GPR119 agonist, preparation method and its usage |
Publications (2)
Publication Number | Publication Date |
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CN104628612A true CN104628612A (en) | 2015-05-20 |
CN104628612B CN104628612B (en) | 2016-06-01 |
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CN201510080394.0A Active CN104628612B (en) | 2015-02-13 | 2015-02-13 | One class itrile group benzol sulfohydrazide class GPR119 agonist, preparation method and its usage |
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CN (1) | CN104628612B (en) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH08238852A (en) * | 1995-03-06 | 1996-09-17 | Nippon Paper Ind Co Ltd | Thermal recording sheet |
EP1314723A1 (en) * | 2001-11-27 | 2003-05-28 | Warner-Lambert Company | Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of neurodegenerative diseases |
WO2009086303A2 (en) * | 2007-12-21 | 2009-07-09 | University Of Rochester | Method for altering the lifespan of eukaryotic organisms |
-
2015
- 2015-02-13 CN CN201510080394.0A patent/CN104628612B/en active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH08238852A (en) * | 1995-03-06 | 1996-09-17 | Nippon Paper Ind Co Ltd | Thermal recording sheet |
EP1314723A1 (en) * | 2001-11-27 | 2003-05-28 | Warner-Lambert Company | Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of neurodegenerative diseases |
WO2009086303A2 (en) * | 2007-12-21 | 2009-07-09 | University Of Rochester | Method for altering the lifespan of eukaryotic organisms |
Non-Patent Citations (3)
Title |
---|
MOHAMMAD REZA GANJALI等: ""Novel erbium (III)-selective fluorimetric bulk optode"", 《SENSORS AND ACTUATORS B》 * |
李占梅等: ""果糖-1, 6-二磷酸酶AMP 变构抑制剂的研究进展"", 《药学学报》 * |
李鹏飞等: ""4-(取代嘧啶-2-基)-1-芳磺酰基氨基脲化合物的合成与表征"", 《有机化学》 * |
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Publication number | Publication date |
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CN104628612B (en) | 2016-06-01 |
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PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Nitrile benzenesulfonylhydrazine type GPR119 agonist, preparation method and application thereof Effective date of registration: 20170816 Granted publication date: 20160601 Pledgee: Guangdong Nanhai Rural Commercial Bank branch branch of Limited by Share Ltd Pledgor: FOSHAN SAIWEISI PHARMACEUTICAL TECHNOLOGY CO., LTD. Registration number: 2017990000756 |
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PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
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Date of cancellation: 20190604 Granted publication date: 20160601 Pledgee: Guangdong Nanhai Rural Commercial Bank branch branch of Limited by Share Ltd Pledgor: FOSHAN SAIWEISI PHARMACEUTICAL TECHNOLOGY CO., LTD. Registration number: 2017990000756 |
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PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20190805 Address after: 233000 Yuhui District, Bengbu City, Anhui Province, No. 1750 Shengli West Road, No. 316 Pioneering Building, Huineng Small and Micro Enterprise Pioneering Center Patentee after: Bengbu Dingrong Science and Technology Information Consulting Co., Ltd. Address before: Chancheng district has 528000 Taiwan public in Guangdong province Foshan City No. 32 first floor 1636, shop No. 1637 Patentee before: FOSHAN SAIWEISI PHARMACEUTICAL TECHNOLOGY CO., LTD. |
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