CN104628547B - A kind of synthetic method of medicine intermediate difluoromethoxy based compound - Google Patents
A kind of synthetic method of medicine intermediate difluoromethoxy based compound Download PDFInfo
- Publication number
- CN104628547B CN104628547B CN201510105183.8A CN201510105183A CN104628547B CN 104628547 B CN104628547 B CN 104628547B CN 201510105183 A CN201510105183 A CN 201510105183A CN 104628547 B CN104628547 B CN 104628547B
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- compound
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- synthetic method
- organic ligand
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- OMHVTHZGAVZRMQ-TXJAFPDNSA-N C/C=C/C=C/P(c1ccccc1)c1ccccc1 Chemical compound C/C=C/C=C/P(c1ccccc1)c1ccccc1 OMHVTHZGAVZRMQ-TXJAFPDNSA-N 0.000 description 1
- PWSJNDSCXGEHDO-XCVCLJGOSA-N C=C/C=C/CP(c1ccccc1)c1ccccc1 Chemical compound C=C/C=C/CP(c1ccccc1)c1ccccc1 PWSJNDSCXGEHDO-XCVCLJGOSA-N 0.000 description 1
- HJSLFCCWAKVHIW-UHFFFAOYSA-N O=C(CCC1)CC1=O Chemical compound O=C(CCC1)CC1=O HJSLFCCWAKVHIW-UHFFFAOYSA-N 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/64—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Description
Claims (9)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510105183.8A CN104628547B (en) | 2015-03-11 | 2015-03-11 | A kind of synthetic method of medicine intermediate difluoromethoxy based compound |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510105183.8A CN104628547B (en) | 2015-03-11 | 2015-03-11 | A kind of synthetic method of medicine intermediate difluoromethoxy based compound |
Publications (2)
Publication Number | Publication Date |
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CN104628547A CN104628547A (en) | 2015-05-20 |
CN104628547B true CN104628547B (en) | 2016-06-08 |
Family
ID=53207844
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN201510105183.8A Active CN104628547B (en) | 2015-03-11 | 2015-03-11 | A kind of synthetic method of medicine intermediate difluoromethoxy based compound |
Country Status (1)
Country | Link |
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CN (1) | CN104628547B (en) |
-
2015
- 2015-03-11 CN CN201510105183.8A patent/CN104628547B/en active Active
Non-Patent Citations (2)
Title |
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Guokai Liu.Selective O‑Difluoromethylation of 1,3-Diones by Bromodifluoromethylating Reagents.《Organic Letters》.2013,第15卷(第5期),1044-1047. * |
Xiaoxi Lin et al..A new method for the synthesis of difluoromethyl enol ethers by O-difluoromethylation of 1,3-diones with ClCF2CO2Et.《Organic & Biomolecular Chemistry》.2015,第13卷3432-3437. * |
Also Published As
Publication number | Publication date |
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CN104628547A (en) | 2015-05-20 |
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Legal Events
Date | Code | Title | Description |
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C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C41 | Transfer of patent application or patent right or utility model | ||
CB03 | Change of inventor or designer information |
Inventor after: Yang Lin Inventor before: He Siwei |
|
COR | Change of bibliographic data | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20160429 Address after: Tianhe District Tong East Road Guangzhou city Guangdong province 510665 B-101 No. 5, room B-118 Applicant after: Guangdong Gaohang Intellectual Property Operation Co., Ltd. Address before: Hangzhou City, Zhejiang province 311605 Jiande Sandu town and village Changshan Panlong No. 26 Applicant before: He Siwei |
|
C41 | Transfer of patent application or patent right or utility model | ||
CB03 | Change of inventor or designer information |
Inventor after: Wang Feng Inventor after: Li Jian Inventor after: Liu Guanghe Inventor after: Zhu Junli Inventor after: Wang Quanqin Inventor after: Zeng Qingyun Inventor after: Cui Meng Inventor before: Yang Lin |
|
COR | Change of bibliographic data | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20160512 Address after: 473039 Wang Cun Township, Wolong District, Henan, Nanyang Applicant after: NANYANG TANWA PHARMACY CO., LTD. Address before: Tianhe District Tong East Road Guangzhou city Guangdong province 510665 B-101 No. 5, room B-118 Applicant before: Guangdong Gaohang Intellectual Property Operation Co., Ltd. |
|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant |