CN104622914A - Vaginal probiotic suppository - Google Patents

Vaginal probiotic suppository Download PDF

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Publication number
CN104622914A
CN104622914A CN201510010621.2A CN201510010621A CN104622914A CN 104622914 A CN104622914 A CN 104622914A CN 201510010621 A CN201510010621 A CN 201510010621A CN 104622914 A CN104622914 A CN 104622914A
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CN
China
Prior art keywords
suppository
vaginal
probiotics
gram
vagina
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510010621.2A
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Chinese (zh)
Inventor
占美华
占帅华
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Individual
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Individual
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Priority to CN201510010621.2A priority Critical patent/CN104622914A/en
Publication of CN104622914A publication Critical patent/CN104622914A/en
Pending legal-status Critical Current

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Abstract

The invention provides a vaginal probiotic suppository, and relates to a method for putting vaginal probiotic suppository to treat patients requiring treatment, particularly patients with vaginal and progenital inflammation when the effect for treating the patients by using antibacterial medicines, antifungal medicines and vaginal probiotics on current market is not good. The vaginal probiotic suppository is prepared by using probiotics as a main material, and the probiotics can be clostridium butyricum, bifidobacterium and bacillus licheniformis. The probiotic suppository can be used for treating wide vaginal inflammations, including colpitis mycotica, bifidobacterium, senile vaginitis and other gynecologic inflammations, and is used for combined treatment including antibacterial medicines, antifungal medicines or probiotic suppository.

Description

Vagina probiotics suppository
The present invention relates to a kind of medicine, be mainly used in treatment woman vagina and episioitis.
At present, treat vaginitis in hospital and use antimicrobial drug, antifungal agent, kill or suppress pathogen, if once it thoroughly can not be killed, will soon stage a comeback.Antibacterial, fungus can produce drug resistance on the one hand; Antibiotic can cause disturbed vaginal flora, scratchiness recurrent exerbation on the other hand.Chinese medicine is better to gynecological inflammation effect, but treatment time is long.The probiotic bacteria----lactobacillus that supplementary woman vagina popular on market is main, treats the prolonged vaginitis of not healing, easily recurring, and has splendid rehabilitation rate 87%-100%, and extremely low relapse rate.Generally, the same day pruritus, pain just alleviates, with a week, pruritus, pain are all eliminated, but need adhere to two months.And lactic acid bacteria powder needs demibain, the vaginal wall adhesion that lactic acid bacteria capsule is easy and impaired, causes pain, all not ideal enough in a word.
The object of this invention is to provide one treat vaginitis rapidly, vaginal suppository easily.
In order to achieve the above object, the present invention adopts clostridium butyricum, bacillus bifidus or Bacillus licheniformis to promote vagina probiotics growth, instead of supplement the main probiotic bacteria of woman vagina, because flora in vagina the field planting easier than the extraneous flora supplemented that vagina self produces.Utilize clostridium butyricum, bacillus bifidus or Bacillus licheniformis promote vagina probiotics growth, suppress vagina and the field planting of pudendum fastbacteria, pathogenic theory, clostridium butyricum or bacillus bifidus are made vaginal suppository, such as miconazole, be placed into vagina.Thus play rapid, the colpitic effect of convenient treatment, make vaginitis patient remove pruritus, pain.According to the above, vagina probiotics suppository probiotic bacteria of the present invention makes major ingredient, and add appropriate microcrystalline Cellulose, magnesium stearate, starch, glucose make vaginal suppository as substrate, vagina clostridium butyricum bolt is not less than 1.5 × 10 containing viable count 8cFU/ gram, bacillus bifidus bolt is not less than 2.38 × 10 containing viable count 8cFU/ gram, the ratio of the parts by weight of raw materials of adding in its formula is: microcrystalline Cellulose: magnesium stearate: starch: glucose=1 gram: 1 gram: 1 gram: 1 gram.Get clostridium butyricum and (be not less than 31.5 × 10 containing clostridium butyricum viable count 7cFU) or bacillus bifidus (be not less than 5.0 × 10 containing the number of active bifid bacteria 8cFU) make 1 vaginal suppository, insert pruritus on the same day, pain is just eliminated.Add with 1 again, just can reach extremely low relapse rate.
In sum, the present invention can treat vaginitis more rapidly, easily than current Lactobacillus powder or capsule, antimicrobial drug, antifungal agent.

Claims (5)

1. vagina probiotics suppository, is characterized in that: be that vaginal suppository made by major ingredient with probiotic bacteria.
2. vagina probiotics suppository according to claim 1, is characterized in that: described probiotic bacteria is the combination in any of one or more of clostridium butyricum, bacillus bifidus, Bacillus licheniformis.
3. vagina probiotics suppository according to claim 1, is characterized in that: vagina probiotics suppository makes major ingredient with probiotic bacteria, adds microcrystalline Cellulose, magnesium stearate, starch, glucose make vaginal suppository as substrate.Vagina clostridium butyricum bolt is not less than 1.5 × 10 containing viable count 8cFU/ gram, bacillus bifidus bolt is not less than 2.38 × 10 containing viable count 8cFU/ gram, the ratio of the parts by weight of raw materials of adding in its formula is: microcrystalline Cellulose: magnesium stearate: starch: glucose=1 gram: 1 gram: 1 gram: 1 gram.
4. vagina probiotics suppository according to claim 1, is characterized in that: every described, clostridium butyricum bolt is not less than 31.5 × 10 containing clostridium butyricum viable count 7cFU.
5. vagina probiotics suppository according to claim 1, is characterized in that: every described, bacillus bifidus bolt is not less than 5.0 × 10 containing the number of active bifid bacteria 8cFU.
CN201510010621.2A 2015-01-06 2015-01-06 Vaginal probiotic suppository Pending CN104622914A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510010621.2A CN104622914A (en) 2015-01-06 2015-01-06 Vaginal probiotic suppository

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510010621.2A CN104622914A (en) 2015-01-06 2015-01-06 Vaginal probiotic suppository

Publications (1)

Publication Number Publication Date
CN104622914A true CN104622914A (en) 2015-05-20

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201510010621.2A Pending CN104622914A (en) 2015-01-06 2015-01-06 Vaginal probiotic suppository

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CN (1) CN104622914A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112057480A (en) * 2020-09-29 2020-12-11 深圳市东荣生物科技有限责任公司 Microbial preparation for treating vaginitis

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1357038A (en) * 1999-06-21 2002-07-03 Vsl制药有限公司 Combination of lactic acid bacteria and its use for prevention and/or treatment of infections and inflammatory conditions
CN1663573A (en) * 2004-03-04 2005-09-07 青岛东海药业有限公司 A stable and safe microecological formulation, its preparation and usage
CN101982180A (en) * 2010-11-01 2011-03-02 西藏贝珠雅药业有限公司 Novel probiotic viable bacteria vaginal suppository body
CN102256610A (en) * 2008-12-18 2011-11-23 伯拉考成像股份公司 Probiotic formulations

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1357038A (en) * 1999-06-21 2002-07-03 Vsl制药有限公司 Combination of lactic acid bacteria and its use for prevention and/or treatment of infections and inflammatory conditions
CN1663573A (en) * 2004-03-04 2005-09-07 青岛东海药业有限公司 A stable and safe microecological formulation, its preparation and usage
CN102256610A (en) * 2008-12-18 2011-11-23 伯拉考成像股份公司 Probiotic formulations
CN101982180A (en) * 2010-11-01 2011-03-02 西藏贝珠雅药业有限公司 Novel probiotic viable bacteria vaginal suppository body

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
刘东红: "微生态制剂的进展与临床应用评价", 《中国医院用药评价与分析》 *
陈万祥等: "地衣芽孢杆菌阴道栓的试制与临床应用", 《中国微生态学杂志》 *
陈万祥等: "地衣芽孢杆菌阴道栓的试制与临床应用", 《中国微生态学杂质》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112057480A (en) * 2020-09-29 2020-12-11 深圳市东荣生物科技有限责任公司 Microbial preparation for treating vaginitis

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Application publication date: 20150520

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