CN104610113B - 一种含腈基苯的n-苯基金刚烷酰胺类化合物及用途 - Google Patents
一种含腈基苯的n-苯基金刚烷酰胺类化合物及用途 Download PDFInfo
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- CN104610113B CN104610113B CN201510075668.7A CN201510075668A CN104610113B CN 104610113 B CN104610113 B CN 104610113B CN 201510075668 A CN201510075668 A CN 201510075668A CN 104610113 B CN104610113 B CN 104610113B
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- glucose
- glucokinase
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化合物 | EC50(nM) |
参比化合物D-1 | 25.8 |
本发明化合物I | 3.9 |
化合物 | S0.5(mM) |
参比化合物D-1 | 3.6 |
本发明化合物I | 2.4 |
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CN201510075668.7A CN104610113B (zh) | 2015-02-12 | 2015-02-12 | 一种含腈基苯的n-苯基金刚烷酰胺类化合物及用途 |
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CN104610113A CN104610113A (zh) | 2015-05-13 |
CN104610113B true CN104610113B (zh) | 2016-02-17 |
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Publication number | Priority date | Publication date | Assignee | Title |
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EP1496052B1 (en) * | 2002-03-26 | 2009-08-05 | Banyu Pharmaceutical Co., Ltd. | Novel aminobenzamide derivative |
EP1532980A1 (en) * | 2003-11-24 | 2005-05-25 | Novo Nordisk A/S | N-heteroaryl indole carboxamides and analogues thereof, for use as glucokinase activators in the treatment of diabetes |
GB0510852D0 (en) * | 2005-05-27 | 2005-07-06 | Astrazeneca Ab | Chemical compounds |
GB0514175D0 (en) * | 2005-07-09 | 2005-08-17 | Astrazeneca Ab | Chemical compounds |
GB0516300D0 (en) * | 2005-08-09 | 2005-09-14 | Astrazeneca Ab | Chemical compounds |
GT200600428A (es) * | 2005-09-30 | 2007-05-21 | Compuestos organicos |
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Denomination of invention: N-phenyl adamantane amide type compound containing nitrile benzene and application of N-phenyl adamantane amide type compound Effective date of registration: 20170816 Granted publication date: 20160217 Pledgee: Guangdong Nanhai Rural Commercial Bank branch branch of Limited by Share Ltd Pledgor: FOSHAN SAIWEISI PHARMACEUTICAL TECHNOLOGY CO., LTD. Registration number: 2017990000756 |
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