CN104605850B - A kind of bladder urine volume real-time monitoring device and method based on electrical impedance tomography technology - Google Patents

A kind of bladder urine volume real-time monitoring device and method based on electrical impedance tomography technology Download PDF

Info

Publication number
CN104605850B
CN104605850B CN201510026916.9A CN201510026916A CN104605850B CN 104605850 B CN104605850 B CN 104605850B CN 201510026916 A CN201510026916 A CN 201510026916A CN 104605850 B CN104605850 B CN 104605850B
Authority
CN
China
Prior art keywords
bladder
urine volume
real
image
module
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201510026916.9A
Other languages
Chinese (zh)
Other versions
CN104605850A (en
Inventor
蒋庆
李日辉
吴俊鹏
李雅宁
刘飏
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Sun Yat Sen University
Original Assignee
National Sun Yat Sen University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National Sun Yat Sen University filed Critical National Sun Yat Sen University
Priority to CN201510026916.9A priority Critical patent/CN104605850B/en
Publication of CN104605850A publication Critical patent/CN104605850A/en
Application granted granted Critical
Publication of CN104605850B publication Critical patent/CN104605850B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/053Measuring electrical impedance or conductance of a portion of the body
    • A61B5/0536Impedance imaging, e.g. by tomography
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/20Measuring for diagnostic purposes; Identification of persons for measuring urological functions restricted to the evaluation of the urinary system
    • A61B5/202Assessing bladder functions, e.g. incontinence assessment
    • A61B5/204Determining bladder volume

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Radiology & Medical Imaging (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)

Abstract

The invention provides a kind of bladder urine volume real-time monitoring device and method based on electrical impedance tomography technology, described device includes excitation module, electrode drive module, signal measurement and conditioning module, data acquisition module, computer control terminal and electrode delamination detection module;Methods described is the test electrod-array by being placed on patient's bladder position body surface face, gathers the electrical impedance data information of body surface;According to the electrical impedance data of the bladder collected, the Two-dimensional Color Image in cross section where Real-time Reconstruction goes out bladder, and the parameter of two dimensional image is extracted by successive image algorithm, according to the current accumulative urine volume of urinary bladder of this parameter prediction, and alarm is sent when the accumulative urine volume of urinary bladder reaches large volume, point out patient's urination or medical personnel to help patient to urinate.The bladder urine volume real-time monitoring device and method provided according to the present invention can realize the urine volume during prediction bladder product urine exactly, improve the precision that bladder urine volume is monitored in real time.

Description

A kind of bladder urine volume real-time monitoring device based on electrical impedance tomography technology and Method
Technical field
The present invention relates to medical detection technology, more particularly, to a kind of based on electrical impedance tomography technology Bladder urine volume real-time monitoring device and method.
Background technology
For the patient with vesical dysfunction, such as the urinary incontinence, spinal cord injury urine meaning deletion patients, it is necessary to supervise in real time Bladder urine volume is surveyed, and reminds controlled micturition or medical personnel to help to urinate in time, could prevent long-pending to urinate one excessively brought and be Row complication.Using methods such as artificial estimation, ultrasound or pressure more than the detection method of current bladder urine volume, these are belonged to greatly Static monitoring techniques, it is impossible to the real-time, urine volume of monitor patient's bladder.
In recent years, bio-electrical impedance technology is applied to the dynamic monitoring of bladder urine volume, its electricity generally by means of body surface Electrode systems apply with small AC measurment curtage to bladder surfaces, corresponding electrical impedance during detection bladder product is urinated And its situation of change, thus predict the situation of patient's bladder product urine.The such as device of conventional four-probe measurement electrical impedance and side Method, generally by two pairs of electrodes to constituting (a pair of exciting and a pair of measuring electrodes).It is defeated to measured target by exciting electrode Enter the alternating current or voltage of constant amplitude, be then pasted into receiving electrode beside two exciting electrodes, can accurately measure by Survey the potential difference at position.But, the apparatus and method of four-probe measurement electrical impedance are too small in the metrical information amount of body surface, Er Qierong It is vulnerable to the influence that patient stirs and urine electrical conductivity changes, it is impossible to the clear urine volume accurately measured in bladder, prompting in time Controlled micturition.
For example, in the prior art, number of patent application is disclosed based on biology for 201310080354.7 Chinese invention The vesica urinaria urine accumulation real-time and device of electrical impedance, the bladder for mainly calculating patient according to the temporal signatures of measurement data are accumulated The accumulative urine volume of urinary bladder calculated, is then compared by urine volume from being directed to the urine volume threshold value of different patient sets in advance, and in wing Guang accumulative urine volume reaches and/or sends alarm during more than the urine volume threshold value.But, this method metrical information amount is small, easily by To the change of body surface contact impedance and the influence of patient's posture, there is larger limitation.
The content of the invention
In view of the above-mentioned deficiencies in the prior art, it is an object of the present invention to provide it is a kind of accurately and reliably, bladder urine volume can be carried out The device of continuous dynamic monitoring, and the method for carrying out real-time dynamic monitoring to bladder urine volume using the device is proposed, according to this The apparatus and method that invention is provided can significantly improve the precision that bladder urine volume is monitored in real time.
The purpose of the present invention is achieved through the following technical solutions:
The invention provides a kind of bladder urine volume real-time monitoring device based on electrical impedance tomography technology, described device Including excitation module, electrode drive module, signal measurement and conditioning module, data acquisition module, computer control terminal and electricity Pole comes off detection module;
The excitation module is used to produce frequency under the control of computer control terminal and the adjustable constant current of amplitude is sinusoidal Wave output signal;
The electrode drive module arbitrarily chooses adjacent by the control of computer control terminal from several electrodes A pair of electrodes injects the constant current sine wave signal output from the excitation module as exciting electrode to human body, while the electricity By the control of computer control terminal, any adjacent pair electrode of choosing from remaining electrode is used as survey to pole drive module Measure electrode;The signal that the signal measurement and conditioning module are measured the measuring electrode is filtered, enhanced processing and to it Carry out AC-DC conversion;
The data acquisition module gathers direct current signal with certain sample frequency, and is uploaded to computer control terminal;
The computer control terminal includes Image Reconstruction module and the real-time monitoring modular of urine volume, described image reconstructed module Finite element modeling is first carried out to the cross section where bladder, including determines circular boundary, triangular unit (this of fixed qty is divided Patent is by taking 576 units as an example), establish after fixed FEM model, according to the collection direct current of the data acquisition module Signal carries out Image Reconstruction to the cross section where bladder, and is showed in the form of Two-dimensional Color Image;The urine volume is real When monitoring modular, parameter extraction, analysis are carried out to the two dimensional images of bladder sections by successive image algorithm, realized to human body wing The real-time monitoring of Guang urine volume, and point out medical personnel to help controlled micturition when urine volume reaches higher value;
The electrode delamination detection module is used for the placement situation for monitoring electrode, will pass through when electrode loosens or come off LED and/or buzzer are alarmed.
Preferably, the excitation module includes direct digital synthesis technique chip and voltage/current conversion circuit;It is described straight The frequency of Digital Frequency Synthesize chip is connect by computer control terminal programming Control, 50KHz, amplitude 600mV constant pressure is output as Sinusoidal signal, exports the constant current sinusoidal signal that 50KHz, amplitude are 1mA after voltage/current conversion circuit.
Preferably, the electrode drive module is made up of four groups every group 16 passage variable connectors, and every group of 16 passages are more Way switch is performed both by 16 and selects 1 function.
Preferably, the signal measurement and conditioning module include two-way programmable filter, two-way instrumentation amplifier With an AC-DC modular converter;
The two-way programmable filter uses bandpass filtering, can remove the pole that the human physiological activity in data causes Low-frequency disturbance, and various High-frequency Interferences, so as to obtain the human impedance measurement data of high s/n ratio;
High frequency ac signal directly can be carried out direct current virtual value calculating by the AC-DC modular converter, and gained is straight Stream signal can be directly used for computer control terminal Image Reconstruction;
Preferably, described image reconstructed module is responsible for completing high data rate collection and Image Reconstruction, improves the reality of system Shi Xing;
The real-time monitoring modular of urine volume predicts the real-time bladder urine volume of patient by following successive image algorithm:
Wherein, VPIt is the accumulative urine volume of current bladder, VREFIt is the urination amount that calibration steps is obtained, APIt is current bladder institute into figure The average conductivity value of picture, AREFIt is the bladder image average conductivity value obtained by calibration steps;
APAnd AREFIt can be obtained by following calibration equation:
Wherein, A represents the average conductivity value of two dimensional image, and N represents the sum of each subdivision unit of image, and б i represent meter The conductivity value of i-th obtained of unit;
The calibration experiments step is as follows:
1) before measurement starts, user must first empty bladder;
2) the bladder urine volume real-time monitoring device is opened, user starts to accumulate urine;
3) user has after strong urine sense, obtains the view data under now filling of bladder state;Stop measurement, use Person urinates, and records last urination amount VREF
4) calculated according to calibration equation and obtain calibration parameter, complete calibration.
Present invention also offers the bladder urine volume method of real-time based on described device, comprise the following steps:
S1. 16 electrodes are equably placed on a flexible annular belt;
S2., the annular belt is lain in abdominal surface position where the bladder of measurand, and corresponding to before human body ilium Upper spine above 10cm circular plane;
S3. the bladder urine volume real-time monitoring device is opened, is measured;
When first in use, each user must first pass through primary calibration experiment;
The calibration experiments step is as follows:
1) before measurement starts, user must first empty bladder;
2) the bladder urine volume real-time monitoring device is opened, user starts to accumulate urine;
3) user has after strong urine sense, obtains the view data under now filling of bladder state;Stop measurement, use Person urinates, and records last urination amount VREF
4) calculated according to calibration equation and obtain calibration parameter, complete calibration;
S4. complete after calibration experiments, the urination amount of input calibration parameter and calibration, carry out normal bladder urine volume and supervise in real time Survey;The Two-dimensional Color Image in cross section where going out bladder by computer control terminal terminal reconstruction, and calculated using successive image Method monitors bladder urine volume in real time.
Preferably, the successive image algorithm is to be carried out according to following computational methods:
Wherein, VPIt is the accumulative urine volume of current bladder, VREFIt is the urination amount that calibration steps is obtained, APIt is current bladder institute into figure The average conductivity value of picture, AREFIt is the bladder image average conductivity value obtained by calibration steps.
APAnd AREFIt can be obtained by following calibration equation:
Wherein, A represents the average conductivity value of two dimensional image, and N represents the sum of each subdivision unit of image, бiRepresent meter The conductivity value of i-th obtained of unit.
The bladder urine volume real-time monitoring device and method provided according to the present invention can realize prediction bladder product urine exactly During urine volume, improve the precision that monitors in real time of bladder urine volume.
Compared with prior art, the invention has the advantages that:
The present invention monitors electrical impedance tomography technology applied to bladder urine volume in real time, can be with Two-dimensional Color Image Mode, situation of change that is directly perceived, quantitatively showing urine volume in bladder;And it can overcome the defect that dynamic is not surveyed in the prior art Amount, information content are few and contact impedance influences the drawback such as big, and the change that effective parameter reflects bladder urine volume is extracted from reconstructed image Change situation;It is nontoxic because electrical impedance tomography is as a kind of cheap not damaged image monitoring technology, can be to patient Long-term, on-line monitor is carried out, with good market application foreground.
Brief description of the drawings
Fig. 1 is that a kind of bladder urine volume based on electrical impedance tomography technology that the embodiment of the present invention 1 is provided is monitored in real time Schematic device;
Fig. 2 is that the embodiment of the present invention 1 is used for the FEM model that bladder cross-sectional image is reconstructed;
Fig. 3 is the bladder urine volume method of real-time structured flowchart of the embodiment of the present invention 2.
Embodiment
It is real-time to bladder urine volume of the present invention based on electrical impedance tomography technology with reference to some embodiments Monitoring device and method are described further.Specific embodiment is of the invention to be further described, non-limiting guarantor of the invention Protect scope.
Embodiment 1:As shown in figure 1, the device that a kind of bladder urine volume based on electrical impedance tomography technology is monitored in real time, Including excitation module, electrode drive module, signal measurement and conditioning module, data acquisition module, computer control terminal and electricity Pole comes off detection module, wherein,
1. module is encouraged, under the control of computer control terminal mainly for generation of frequency and the adjustable constant current of amplitude just String wave output signal.
Specifically, the module includes direct digital synthesis technique (DDS) chip and voltage/current conversion circuit.DDS chips Frequency by computer control terminal programming Control, 50KHz, amplitude 600mV constant pressure sinusoidal signal are typically output as, by electricity The constant current sinusoidal signal that 50KHz, amplitude are 1mA is exported after pressure/current converter circuit;
2. electrode drive module, the control instructed by computer control terminal is arbitrarily chosen adjacent from several electrodes A pair of electrodes as exciting electrode to human body inject from it is described excitation module constant current sinusoidal signal, while the electrode drive The control that dynamic model block is instructed by computer control terminal any adjacent pair electrode of choosing from remaining electrode is used as survey Measure electrode.If electrode has 16, once complete measurement (two field picture) includes 16 × 13=208 data;
Particularly, when injecting exciting current and measurement voltage, the electrode drive module is by four 16 passage multichannels Switch is constituted, and each 16 passage variable connector is performed both by 16 and selects 1 function.
3. signal measurement and conditioning module, the signal that measuring electrode in the electrode drive module is measured is filtered, Enhanced processing simultaneously carries out AC-DC conversion to it;
Specifically, when carrying out signal measurement and conditioning, the signal measurement and conditioning module are by two-way programmable filter Device, two-way instrumentation amplifier and an AC-DC modular converter are constituted.Programmable filter is filtered using 50KHz band logicals Ripple, can remove the very low frequencies interference that such as breathing, heartbeat human physiological activity cause in data, and various high frequencies are done Disturb, so as to obtain the human impedance measurement data of high s/n ratio.AC-DC modular converter directly can believe high-frequency ac Number direct current virtual value calculating is carried out, gained direct current signal can be directly used for computer control terminal Image Reconstruction, not only subtract significantly The influence in terms of AC signal demodulation brings power consumption and speed is lacked, and high sampling rate has been wanted when reducing data sampling Ask, reduce the complexity of hardware design.
4. data acquisition module, with certain sample frequency to the direct current by the signal measurement and conditioning module conversion Signal is sampled, and is uploaded to computer control terminal;
5. electrode delamination detection module, the placement situation for monitoring electrode, will pass through when electrode loosens or come off LED and/or buzzer are alarmed.
6. computer control terminal, including:
Image Reconstruction module, first carries out finite element modeling to the cross section where bladder, including determines circular boundary, divides The triangular unit (this patent is as shown in Figure 2 by taking 576 units as an example) of fixed qty, is established after fixed FEM model, Image Reconstruction is carried out to the cross section where bladder according to the collection direct current signal of the data acquisition module, and with two-dimensional color The form of image shows;
The real-time monitoring modular of urine volume, carries out parameter to the two dimensional image of bladder sections by the subsequent treatment algorithm of image and carries Take, analyze, realize the real-time monitoring to human bladder's urine volume, and point out medical personnel to help patient when urine volume reaches higher value Urination.
Specifically, described bladder urine volume real-time monitoring device, when carrying out Image Reconstruction, described Image Reconstruction mould Block, can complete data acquisition and the Image Reconstruction of high-speed, improve the real-time of system.The real-time monitoring modular of described urine volume, And the real-time bladder urine volume of patient is predicted by following successive image algorithm:
Wherein, VPIt is the accumulative urine volume of current bladder, VREFIt is the urination amount that calibration steps is obtained, APIt is current bladder institute into figure The average conductivity value of picture, AREFIt is the bladder image average conductivity value obtained by calibration steps.
APAnd AREFIt can be obtained by following calibration equation:
Wherein, AREFThe average conductivity value of two dimensional image in calibration steps is represented, N represents the FEM model of this image The sum of subdivision unit, бiRepresent the conductivity value for i-th of unit that calculating is obtained.Under normal circumstances, N quantity is to determine 's.
Embodiment 2:As shown in figure 3, a kind of bladder urine volume method of real-time of utilization electrical impedance tomography technology, bag Include following steps:
S1, equably ring sets 16 electrodes on a flexible annular belt, and electrode is common Ag/AgCl electrocardios electricity Pole;
S2, abdominal surface position where annular belt to be lain in the bladder of measurand, and corresponding to human body anterior superior spine Above 10cm circular plane;
It is best to reach with sand paper polishing skin, it is necessary to remove the hair of patient surface skin before annular electrode is pasted Measurement effect.Stationary annular waistband is needed during measurement, measurement result otherwise will be influenceed;
S3, opens the device described in embodiment 1, measures;
S4, if using first, each user must first pass through primary calibration experiment.
The calibration experiments step is as follows:
S41, before measurement starts, the first empty bladder of user's palpus, in order to obtain cross section under bladder emptying state Background data, for follow-up Image Reconstruction;
S42, opens the described device of embodiment 1, and user starts to accumulate urine;
S43, user has after strong urine sense, obtains the view data under now filling of bladder state;Stop measurement, make User urinates, and records last urination amount, is designated as VREF
Two-dimensional Color Image under S44, reconstruct filling of bladder state, and calibration parameter A is calculated according to calibration equationREF, it is complete Into calibration.
Specifically, the Image Reconstruction in bladder cross section is reconstructed using FEM model as shown in Figure 2, each of which Individual triangular mesh represents a finite element fission unit.
Specifically, AREFIt can be obtained by following calibration equation:
Wherein, AREFThe average conductivity value of two dimensional image in calibration steps is represented, N represents the FEM model of this image The sum of subdivision unit, бiRepresent the conductivity value for i-th of unit that calculating is obtained.Under normal circumstances, N quantity is to determine 's.
S5, is completed after calibration experiments, inputs calibration parameter AREFWith calibration urine volume VREF, carry out normal bladder urine volume and supervise in real time Survey, preparation process such as S1-S3;
S6. the Two-dimensional Color Image in cross section where going out bladder by computer control terminal terminal reconstruction, and utilize step A in rapid S44REFAlgorithm calculate present image average conductivity value AP.The real-time monitoring modular of urine volume will according to above-mentioned parameter, Realize to human bladder's urine volume VPReal-time monitoring, and when urine volume reaches higher value point out medical personnel help controlled micturition.
Specifically, the present invention by following successive image algorithm to current human's bladder urine volume VPIt is predicted:
Wherein, VPIt is the accumulative urine volume of current bladder, VREFIt is the urination amount that calibration steps is obtained, APIt is current bladder institute into figure The average conductivity value of picture, AREFIt is the bladder image average conductivity value obtained by calibration steps.
The present invention can realize the real-time monitoring to human bladder's urine volume exactly, and reach in urine volume by the above method Medical personnel are pointed out to help controlled micturition to during higher value.
Finally illustrate, the above embodiments are merely illustrative of the technical solutions of the present invention and it is unrestricted, although with reference to compared with The present invention is described in detail good embodiment, it will be understood by those within the art that, can be to skill of the invention Art scheme is modified or equivalent substitution, and without departing from the objective and scope of the technical program, it all should cover in the present invention Right among.

Claims (6)

1. a kind of bladder urine volume real-time monitoring device based on electrical impedance tomography technology, it is characterised in that including excited modes Block, electrode drive module, signal measurement and conditioning module, data acquisition module, computer control terminal and electrode delamination detection Module;
The excitation module is used to produce frequency under the control of computer control terminal and the adjustable constant current sine wave of amplitude is defeated Go out signal;
The electrode drive module chooses adjacent pair by the way that the control of computer control terminal is any from several electrodes Electrode injects the constant current sine wave signal output from the excitation module as exciting electrode to human body, while the electrode drives By the control of computer control terminal, any adjacent pair electrode of choosing from remaining electrode is used as measurement electricity to dynamic model block Pole;
The signal that the signal measurement and conditioning module are measured the measuring electrode is filtered and enhanced processing and it entered Row AC-DC conversion;
The data acquisition module is used to gather direct current signal, and is uploaded to computer control terminal;
The computer control terminal includes Image Reconstruction module and the real-time monitoring modular of urine volume;
Described image reconstructed module first carries out finite element modeling to the cross section where bladder, including determines circular boundary, divides The triangular unit of fixed qty, is established after fixed FEM model, is believed according to the direct current of the data collecting module collected Number Image Reconstruction is carried out to the cross section where bladder, and showed in the form of Two-dimensional Color Image;
The real-time monitoring modular of urine volume, carries out parameter extraction to the two dimensional image of bladder sections by successive image algorithm and divides Analysis, realizes the real-time monitoring to human bladder's urine volume;
The electrode delamination detection module is used for the placement situation for monitoring electrode, will be by LED when electrode loosens or come off Lamp and/or buzzer are alarmed;
Described image reconstructed module is responsible for completing high data rate collection and Image Reconstruction, improves the real-time of system;
The real-time monitoring modular of urine volume predicts the real-time bladder urine volume of patient by following successive image algorithm:
V P = A P A R E F × V R E F
Wherein, VPIt is the accumulative urine volume of current bladder, VREFIt is the urination amount that calibration steps is obtained, APIt is current bladder institute into image Average conductivity value, AREFIt is the bladder image average conductivity value obtained by calibration steps;
APAnd AREFIt can be obtained by following calibration equation:
A = Σ i = 1 N σ i N
Wherein, A represents the average conductivity value of two dimensional image, and N represents the sum of each subdivision unit of image,Expression is calculated The conductivity value of i-th of the unit arrived;
The calibration steps is as follows:
1) before measurement starts, user must first empty bladder;
2) the bladder urine volume real-time monitoring device is opened, user starts to accumulate urine;
3) user has after strong urine sense, obtains the view data under now filling of bladder state;Stop measurement, user row Urine, and record last urination amount VREF
4) calculated according to calibration equation and obtain calibration parameter, complete calibration.
2. bladder urine volume real-time monitoring device according to claim 1, it is characterised in that the excitation module includes direct Digital Frequency Synthesize chip and voltage/current conversion circuit;
The frequency of the direct digital synthesis technique chip is by computer control terminal programming Control, and exporting 50KHz, amplitude is 600mV constant pressure sinusoidal signal, exports the constant current sinusoidal signal that 50KHz, amplitude are 1mA after voltage/current conversion circuit.
3. bladder urine volume real-time monitoring device according to claim 1, it is characterised in that the electrode drive module is by four Every group of 16 passage variable connector of group is constituted, and every group of 16 passage variable connectors are performed both by 16 and select 1 function.
4. bladder urine volume real-time monitoring device according to claim 1, it is characterised in that the signal measurement and conditioning mould Block includes two-way programmable filter, two-way instrumentation amplifier and an AC-DC modular converter;
The two-way programmable filter uses bandpass filtering, can remove the very low frequencies that the human physiological activity in data causes Interference, and various High-frequency Interferences, so as to obtain the human impedance measurement data of high s/n ratio;
High frequency ac signal directly can be carried out direct current virtual value calculating, gained direct current letter by the AC-DC modular converter Number it can be directly used for computer control terminal Image Reconstruction.
5. a kind of bladder urine volume method of real-time of any one claim described device of utilization Claims 1-4 4, it is special Levy and be, comprise the following steps:
S1. 16 electrodes are equably placed on annular belt;
S2., the annular belt is lain in abdominal surface position where the bladder of measurand, and corresponding to human body anterior superior spine Above 10cm circular plane;
S3. the bladder urine volume real-time monitoring device is opened, is measured;
When first in use, each user must first pass through primary calibration experiment;
The calibration experiments step is as follows:
1) before measurement starts, user must first empty bladder;
2) the bladder urine volume real-time monitoring device is opened, user starts to accumulate urine;
3) user has after strong urine sense, obtains the view data under now filling of bladder state;Stop measurement, user row Urine, and record last urination amount VREF
4) calculated according to calibration equation and obtain calibration parameter, complete calibration;
S4. complete after calibration experiments, the urination amount of input calibration parameter and calibration, carry out normal bladder urine volume and monitor in real time;It is logical The Two-dimensional Color Image in cross section where computer control terminal reconstructs bladder is crossed, and is monitored in real time using successive image algorithm Bladder urine volume.
6. bladder urine volume method of real-time according to claim 5, it is characterised in that the successive image algorithm be by Carried out according to following computational methods:
V P = A P A R E F × V R E F
Wherein, VPIt is the accumulative urine volume of current bladder, VREFIt is the urination amount that calibration steps is obtained, APIt is current bladder institute into image Average conductivity value, AREFIt is the bladder image average conductivity value obtained by calibration steps;
APAnd AREFIt can be obtained by following calibration equation:
A = Σ i = 1 N σ i N
Wherein, A represents the average conductivity value of two dimensional image, and N represents the sum of each subdivision unit of image,Expression is calculated The conductivity value of i-th of the unit arrived.
CN201510026916.9A 2015-01-19 2015-01-19 A kind of bladder urine volume real-time monitoring device and method based on electrical impedance tomography technology Active CN104605850B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510026916.9A CN104605850B (en) 2015-01-19 2015-01-19 A kind of bladder urine volume real-time monitoring device and method based on electrical impedance tomography technology

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510026916.9A CN104605850B (en) 2015-01-19 2015-01-19 A kind of bladder urine volume real-time monitoring device and method based on electrical impedance tomography technology

Publications (2)

Publication Number Publication Date
CN104605850A CN104605850A (en) 2015-05-13
CN104605850B true CN104605850B (en) 2017-08-01

Family

ID=53140710

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201510026916.9A Active CN104605850B (en) 2015-01-19 2015-01-19 A kind of bladder urine volume real-time monitoring device and method based on electrical impedance tomography technology

Country Status (1)

Country Link
CN (1) CN104605850B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10602973B2 (en) 2015-05-06 2020-03-31 National University Of Ireland, Galway Non-invasive detection of the backflow of urine
US10685249B2 (en) * 2016-04-12 2020-06-16 GOGO Band, Inc. Urination prediction and monitoring
CN109498013B (en) * 2018-12-12 2020-10-09 北京航空航天大学 Bladder volume measurement method based on single-layer EIT electrode edge effect
CN109998546A (en) * 2019-01-25 2019-07-12 芯海科技(深圳)股份有限公司 A kind of evaluation method of human body impedance signal's mass
CN110859636B (en) * 2019-12-12 2020-12-25 北京航空航天大学 Dynamic bladder volume measurement method insensitive to urine conductivity
CN111407314A (en) * 2020-04-09 2020-07-14 重庆市中医院 Clinical bladder urine volume real-time supervision device based on ultrasonic probe array
CN111790011A (en) * 2020-07-28 2020-10-20 曾洁 Suction adjusting platform and method applying urine volume detection

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102551712A (en) * 2011-06-13 2012-07-11 广州安德生物科技有限公司 Non-invasive type urination alarming device based on bioelectrical impedance and monitoring method
CN102670198A (en) * 2011-03-16 2012-09-19 德尔格医疗有限责任公司 Method for electroimpedance tomography
CN103126672A (en) * 2013-03-13 2013-06-05 中山大学 Vesica urinaria urine accumulation real-time monitoring method and device based on bioelectrical impedance
CN103153180A (en) * 2010-10-07 2013-06-12 斯威斯托姆公开股份有限公司 Sensor device for electrical impedance tomography imaging, electrical impedance tomography imaging intrument and electrical impedance tomography method
CN103622693A (en) * 2013-11-28 2014-03-12 中山大学 Portable bio-electrical impedance measurement device

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2219523B1 (en) * 2007-11-08 2013-03-06 Inolact Ltd. Measuring fluid excreted from an organ
WO2010126827A2 (en) * 2009-05-01 2010-11-04 Sanguis Technologies, Llc Non-invasive analyte measurement

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103153180A (en) * 2010-10-07 2013-06-12 斯威斯托姆公开股份有限公司 Sensor device for electrical impedance tomography imaging, electrical impedance tomography imaging intrument and electrical impedance tomography method
CN102670198A (en) * 2011-03-16 2012-09-19 德尔格医疗有限责任公司 Method for electroimpedance tomography
CN102551712A (en) * 2011-06-13 2012-07-11 广州安德生物科技有限公司 Non-invasive type urination alarming device based on bioelectrical impedance and monitoring method
CN103126672A (en) * 2013-03-13 2013-06-05 中山大学 Vesica urinaria urine accumulation real-time monitoring method and device based on bioelectrical impedance
CN103622693A (en) * 2013-11-28 2014-03-12 中山大学 Portable bio-electrical impedance measurement device

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
A 3D VisualizationMethod for Bladder Filling Examination Based on EIT;Wei He,et al.;《Computational and Mathematical Methods in Medicine》;20121231;第2012卷;第1-9页 *
基于虚拟仪器的电阻抗断层成像测量系统设计;李日辉等;《中国医疗设备》;20141231;第29卷(第3期);第11-13页 *

Also Published As

Publication number Publication date
CN104605850A (en) 2015-05-13

Similar Documents

Publication Publication Date Title
CN104605850B (en) A kind of bladder urine volume real-time monitoring device and method based on electrical impedance tomography technology
Zhang et al. Advancing hand gesture recognition with high resolution electrical impedance tomography
US9763580B2 (en) Internal bleeding detection apparatus
US20190295729A1 (en) Universal non-invasive blood glucose estimation method based on time series analysis
CN104363824B (en) The measurement of real-time QRS duration in electrocardiogram
CN102551712B (en) Non-invasive type urination alarming device based on bioelectrical impedance and monitoring method
CN107743378A (en) The Noninvasive testing of backflow to urine
CN103445770B (en) Urination sensing detection method and device
US11406304B2 (en) Systems and methods for physiological sign analysis
CN104545912A (en) Cardiac and pulmonary impedance measuring method and device
CN103405225B (en) A kind of pain that obtains feels the method for evaluation metrics, device and equipment
Adler Electrical impedance tomography
Taruno et al. 4D brain activity scanner using Electrical Capacitance Volume Tomography (ECVT)
CN204909917U (en) Intelligent sheet of sleep guardianship and medical diagnosis based on cloth sensor
CN103976737A (en) Method and system for analyzing correlation between respiration impedance of left lung and right lung
Mosquera et al. Implementation of a low cost prototype for electrical impedance tomography based on the integrated circuit for body composition measurement AFE4300
CN107320102A (en) A kind of bladder urination time reminding method and apparatus for evaluating based on forecast model
AU2010244220A1 (en) Impedance tomography apparatus
CN111134641A (en) Sleep monitoring chip system and sleep monitoring chip
CN103222864B (en) Self-adaption electrocardiograph (ECG) detection method and monitoring system thereof
Tiwari et al. Stress and anxiety measurement" in-the-wild" using quality-aware multi-scale hrv features
CN103340639A (en) Bioelectrical impedance based urge incontinence recognition method
CN104523271B (en) A kind of myoelectricity surveys pain device
CN109222934B (en) System and method for bio-electrical impedance coherence measurement
CN103251392A (en) Health monitoring method and device

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant