CN104592395A - Preparation method and application of VEGFR2 (Vascular Endothelial Growth Factor Receptor 2) single-chain antibody and MICA fusion protein - Google Patents
Preparation method and application of VEGFR2 (Vascular Endothelial Growth Factor Receptor 2) single-chain antibody and MICA fusion protein Download PDFInfo
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- CN104592395A CN104592395A CN201510038297.5A CN201510038297A CN104592395A CN 104592395 A CN104592395 A CN 104592395A CN 201510038297 A CN201510038297 A CN 201510038297A CN 104592395 A CN104592395 A CN 104592395A
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Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017222556A3 (en) * | 2016-06-24 | 2018-04-19 | Avidbiotics Corp. | Insertable variable fragments of antibodies and modified a1-a2 domains of nkg2d ligands |
CN109678963A (en) * | 2018-12-18 | 2019-04-26 | 中国药科大学 | A kind of preparation and its application of the bispecific antibody for targeting CD24 and activating NK cell |
CN109762785A (en) * | 2018-12-10 | 2019-05-17 | 吴江近岸蛋白质科技有限公司 | A kind of efficient application is in the method for the non-trophoderm in vitro culture of NK cells of human beings |
CN110903402A (en) * | 2019-11-27 | 2020-03-24 | 中国药科大学 | Bispecific fusion protein and construction method and application thereof |
CN111333732A (en) * | 2019-12-17 | 2020-06-26 | 中国药科大学 | Preparation and application of bispecific antibody targeting human BCMA and activating NK cells |
CN114292337A (en) * | 2021-12-17 | 2022-04-08 | 中南大学 | Soluble NK-CAR fusion protein, preparation method and application in mediated immune cell targeted tumor cell killing medicine |
WO2023274352A1 (en) * | 2021-07-02 | 2023-01-05 | Laekna Therapeutics Shanghai Co., Ltd. | Depletion of activated hepatic stellate cells (hscs) and uses thereof |
WO2024055995A1 (en) * | 2022-09-14 | 2024-03-21 | 寻济生物科技(北京)有限公司 | Anti-vegfa fusion protein, and preparation method therefor and use thereof |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2020172259A1 (en) * | 2019-02-20 | 2020-08-27 | Research Institute At Nationwide Children's Hospital | Cancer-targeted, virus-encoded, regulatable t (catvert) or nk cell (catvern) linkers |
Citations (2)
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CN101863980B (en) * | 2009-12-31 | 2013-05-08 | 中国药科大学 | Whole human source anti-vascular endothelial cell growth factor receptor 2 single chain antibody |
CN104203981A (en) * | 2011-12-19 | 2014-12-10 | 合成免疫股份有限公司 | Bispecific antibody molecule |
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2015
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Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101863980B (en) * | 2009-12-31 | 2013-05-08 | 中国药科大学 | Whole human source anti-vascular endothelial cell growth factor receptor 2 single chain antibody |
CN104203981A (en) * | 2011-12-19 | 2014-12-10 | 合成免疫股份有限公司 | Bispecific antibody molecule |
Non-Patent Citations (3)
Title |
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戴丽娟等: "抗VEGFR2/抗CD3双特异单链抗体的表达及初步活性检测", 《细胞与分子免疫学杂志》 * |
李海鑫等: "抗血管内皮生长因子受体2单链抗体的筛选及表达纯化", 《药物生物技术》 * |
贾玉: "Herceptin-NKG2D配体的融合蛋白的抗肿瘤研究", 《中国优秀硕士学位论文全文数据库 基础科学辑》 * |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017222556A3 (en) * | 2016-06-24 | 2018-04-19 | Avidbiotics Corp. | Insertable variable fragments of antibodies and modified a1-a2 domains of nkg2d ligands |
CN109762785A (en) * | 2018-12-10 | 2019-05-17 | 吴江近岸蛋白质科技有限公司 | A kind of efficient application is in the method for the non-trophoderm in vitro culture of NK cells of human beings |
CN109762785B (en) * | 2018-12-10 | 2022-06-24 | 苏州近岸蛋白质科技股份有限公司 | Method for efficiently applying to in-vitro culture of human NK cell non-trophoblast |
CN109678963A (en) * | 2018-12-18 | 2019-04-26 | 中国药科大学 | A kind of preparation and its application of the bispecific antibody for targeting CD24 and activating NK cell |
CN110903402A (en) * | 2019-11-27 | 2020-03-24 | 中国药科大学 | Bispecific fusion protein and construction method and application thereof |
CN110903402B (en) * | 2019-11-27 | 2023-02-28 | 中国药科大学 | Bispecific fusion protein and construction method and application thereof |
CN111333732A (en) * | 2019-12-17 | 2020-06-26 | 中国药科大学 | Preparation and application of bispecific antibody targeting human BCMA and activating NK cells |
CN111333732B (en) * | 2019-12-17 | 2023-02-28 | 中国药科大学 | Preparation and application of bispecific antibody targeting human BCMA and activating NK cells |
WO2023274352A1 (en) * | 2021-07-02 | 2023-01-05 | Laekna Therapeutics Shanghai Co., Ltd. | Depletion of activated hepatic stellate cells (hscs) and uses thereof |
CN114292337A (en) * | 2021-12-17 | 2022-04-08 | 中南大学 | Soluble NK-CAR fusion protein, preparation method and application in mediated immune cell targeted tumor cell killing medicine |
WO2024055995A1 (en) * | 2022-09-14 | 2024-03-21 | 寻济生物科技(北京)有限公司 | Anti-vegfa fusion protein, and preparation method therefor and use thereof |
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Inventor after: Zhang Juan Inventor after: Wang Min Inventor after: DESMOND OMANE ACHEAMPONG Inventor after: Tang Mingying Inventor after: Wang Youfu Inventor after: Zhao Xin Inventor after: Yuan Xibin Inventor before: Wang Min Inventor before: DESMOND OMANE ACHEAMPONG Inventor before: Tang Mingying Inventor before: Zhang Juan Inventor before: Wang Youfu Inventor before: Zhao Xin Inventor before: Yuan Xibin |
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Granted publication date: 20171114 Termination date: 20220127 |