CN104589728A - Cold-stamping composite hard tablet for solid medicine - Google Patents
Cold-stamping composite hard tablet for solid medicine Download PDFInfo
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- CN104589728A CN104589728A CN201410852827.5A CN201410852827A CN104589728A CN 104589728 A CN104589728 A CN 104589728A CN 201410852827 A CN201410852827 A CN 201410852827A CN 104589728 A CN104589728 A CN 104589728A
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B15/00—Layered products comprising a layer of metal
- B32B15/04—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material
- B32B15/08—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
- B32B15/082—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin comprising vinyl resins; comprising acrylic resins
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B15/00—Layered products comprising a layer of metal
- B32B15/04—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material
- B32B15/08—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
- B32B15/095—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin comprising polyurethanes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B15/00—Layered products comprising a layer of metal
- B32B15/20—Layered products comprising a layer of metal comprising aluminium or copper
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/06—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material
- B32B27/08—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/30—Layered products comprising a layer of synthetic resin comprising vinyl (co)polymers; comprising acrylic (co)polymers
- B32B27/304—Layered products comprising a layer of synthetic resin comprising vinyl (co)polymers; comprising acrylic (co)polymers comprising vinyl halide (co)polymers, e.g. PVC, PVDC, PVF, PVDF
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/32—Layered products comprising a layer of synthetic resin comprising polyolefins
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/34—Layered products comprising a layer of synthetic resin comprising polyamides
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/40—Layered products comprising a layer of synthetic resin comprising polyurethanes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B7/00—Layered products characterised by the relation between layers; Layered products characterised by the relative orientation of features between layers, or by the relative values of a measurable parameter between layers, i.e. products comprising layers having different physical, chemical or physicochemical properties; Layered products characterised by the interconnection of layers
- B32B7/04—Interconnection of layers
- B32B7/12—Interconnection of layers using interposed adhesives or interposed materials with bonding properties
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D65/00—Wrappers or flexible covers; Packaging materials of special type or form
- B65D65/38—Packaging materials of special type or form
- B65D65/40—Applications of laminates for particular packaging purposes
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
- C09J127/00—Adhesives based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Adhesives based on derivatives of such polymers
- C09J127/02—Adhesives based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Adhesives based on derivatives of such polymers not modified by chemical after-treatment
- C09J127/04—Adhesives based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Adhesives based on derivatives of such polymers not modified by chemical after-treatment containing chlorine atoms
- C09J127/06—Homopolymers or copolymers of vinyl chloride
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
- C09J167/00—Adhesives based on polyesters obtained by reactions forming a carboxylic ester link in the main chain; Adhesives based on derivatives of such polymers
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
- C09J167/00—Adhesives based on polyesters obtained by reactions forming a carboxylic ester link in the main chain; Adhesives based on derivatives of such polymers
- C09J167/02—Polyesters derived from dicarboxylic acids and dihydroxy compounds
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
- C09J169/00—Adhesives based on polycarbonates; Adhesives based on derivatives of polycarbonates
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
- C09J175/00—Adhesives based on polyureas or polyurethanes; Adhesives based on derivatives of such polymers
- C09J175/04—Polyurethanes
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- C—CHEMISTRY; METALLURGY
- C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
- C22C—ALLOYS
- C22C21/00—Alloys based on aluminium
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- Organic Chemistry (AREA)
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Abstract
The invention relates to a cold-stamping composite hard tablet for solid medicine and belongs to the technical field of pharmaceutical packaging materials. The cold-stamping composite hard tablet for solid medicine of the invention comprises a polyamide layer, an aluminum foil layer and a polyvinyl chloride layer which are sequentially arranged, wherein a glue layer is arranged between the aluminum foil layer and the polyvinyl chloride layer. According to the invention, each surface of the aluminum foil layer comprises an aluminum phosphate film and a rough layer, the surface of the aluminum foil layer is coated with a polyurethane resin layer and the polyurethane resin layer is located between the aluminum foil layer and the polyamide layer; a maleic anhydride modified polyethylene layer and an acrylic acid modified polyethylene layer are orderly arranged between the polyamide layer and the aluminum foil layer; and adhesive layers are both arranged between the acrylic acid modified polyethylene layer and the polyurethane resin layer and between the aluminum foil layer and the polyurethane resin layer. According to the invention, the glue density of the glue layer is 4.9-5.1g/cm<3>, the thickness of the polyamide layer is 28-32 mu m, the thickness of the aluminum foil layer is 48-53 mu m, the thickness of the polyurethane resin layer is 52-58 mu m and the total thickness of the composite hard tablet is 140-143 mu m. The composite hard tablet of the invention has long service life and small vapor and oxygen transmittance.
Description
Technical field
The invention belongs to acceptable packaging material technical field, particularly a kind of cold stamping solid medicinal composite hard sheet.
Background technology
PVC plastic uptake and medical aluminum foil PTP is adopted to carry out heat seal packaging in existing Key works Drug packing industry, there is performance deficiency such as obstruct water vapour, oxygen etc. in PVC, the resting periods such as medicine, health products, food are short, and the light transmission of PVC effectively can not intercept ultraviolet, and easily aging under Ultraviolet radiation, produce toxic gas.Although China's pharmaceuticals industry and health products, food service industry develop rapidly, drug packing material have also been obtained develop rapidly, but the hot belt type cold stamping composite hard sheet structure existed in the industry is at present nylon layer (both aramid layer), aluminium foil layer, shaping rear hot pressing and plastic uptake PVC involution, this series products easily causes between nylon layer and aluminium foil layer and causes aluminium foil layer damaged in layering and punching course in cold stamping process, affects shelf life of products and reduces production efficiency.In addition, the material property in existing drug packing material is general, uses 3003 alloys or 8011 alloys as the aluminium foil in drug packing material.With the aluminium foil of 3003 alloy production, there is good punching performance, but due to Mn constituent content in alloy too high, when carrying out homogenizing annealing, crystal grain is easily grown up, when being rolled down to finished product thickness, surface inevitably there will be coarse-grain striped, and impact normally uses.On the other hand, due to the characteristic of 3003 alloys self, the intensity of material is higher, comparatively large to the loss of rolling equipment and punching device, needs to add a large amount of copper, manganese metal simultaneously, increases the production cost of enterprise.With the tableware aluminium foil of 8011 alloy production, although can overcome the some shortcomings of 3003 alloys, because in 8011 alloys, alloying element content is lower, but performance is partially soft, is not suitable for high-speed punching, and the punching degree of depth is not enough, and its scope of application is very restricted.
Summary of the invention
The object of the invention is to there are the problems referred to above for existing technology, propose the cold stamping solid medicinal composite hard sheet of a kind of long service life, steam, OTR oxygen transmission rate reduction.
Object of the present invention realizes by following technical proposal: a kind of cold stamping solid medicinal composite hard sheet, comprise the aramid layer set gradually, aluminium foil layer, polyvinyl chloride layer, a dry multiple glue layer is provided with between described aluminium foil layer and described polyvinyl chloride layer, it is characterized in that, the surface of described aluminium foil layer comprises aluminum phosphate film and rough layer, aluminium foil layer surface be coated with urethane resin layer and described urethane resin layer between aluminium foil layer and aramid layer, maleic anhydride modified polyethylene layer and acrylic acid modified polyethylene layer is also disposed with between described aramid layer and described aluminium foil layer, described acrylic acid modified polyethylene layer and described urethane resin layer, adhesive layer is equipped with between aluminium foil layer and urethane resin layer, the density of described dry multiple glue layer glue is 4.9-5.1g/cm
3, the thickness of described aramid layer is 28-32 μm, and the thickness of aluminium foil layer is 48-53 μm, and the thickness of polyvinyl chloride layer is 52-58 μm, and the gross thickness of described cold stamping solid medicinal composite hard sheet is 140-143 μm.
In above-mentioned cold stamping solid medicinal composite hard sheet, as preferably, composition and the percentage by weight of described aluminium foil layer aluminum foil material are: Si:0.35-0.50%, Fe:0.9-1.20%, Cu:0.05-0.12%, Mn:0.50-0.60%, Mg:0.02-0.05%, Cr:0.02-0.05%, Zn:0.02-0.05%, Ti:0.02-0.05%, Al surplus.
The present invention is on the basis of 8011 alloys, component and content thereof are optimized, reduce Si constituent content, improve the content of Mn element, the intensity of material can be improved, simultaneously again with the Fe element of high-load, reduce the degree of supersaturation of Mn in aluminium, reduce the microsegregation of Mn, avoid the phenomenon of aluminium foil grain growth when homogenizing annealing.And reasonable compatibility other elements and content thereof, gather the advantage of 8011 alloys, not only increased aluminium foil intensity, rupture strength, also improved the rolling stability of aluminium foil simultaneously, production efficiency and yield rate, improve the surface quality of aluminium foil.
In above-mentioned cold stamping solid medicinal composite hard sheet, as preferably, obtaining by following method of described aluminium foil:
S1, melting, casting: according to described in above-mentioned aluminium foil composition and percentage by weight take raw material, the raw material taken is carried out melting at 730-760 DEG C, then carries out casting and obtain blank, the sotck thinkness after casting is 7.2 ± 0.3mm;
S2, homogenizing annealing: above-mentioned blank is carried out homogenizing annealing process at 560-580 DEG C, come out of the stove after isothermal holding 18-23 hour and be cooled to normal temperature;
S3, cold rolling: cooled blank is carried out cold rolling, during rolling the first passage, working modulus is 60-80%, and back pass working modulus remains on 35-45%, under 320-380 DEG C of condition, intermediate annealing is carried out to 0.6-0.8mm, insulation 25-28 hour through 5-6 passes;
S4, paper tinsel roll, by the aluminum strip after intermediate annealing through the aluminium foil of 2-3 passes to 0.20-0.26mm thickness.
In above-mentioned cold stamping solid medicinal composite hard sheet, as preferably, the binding agent of described adhesive layer is made up of each component of following weight percentage: acetone: 25-32%; Chloroethylene-vinyl acetate-maleic acid terpolymer resin: 18-25%; The copolymer of ethylene glycol-dimethyltrimethylene glycol-terephthalate-last of the ten Heavenly stems diester: 30-40%; Polyurethane: 5-10%; Merlon: 5-10%; Polyestercarbonate: 5-10%.
Not only thoroughly overcome the shortcoming of existing non-environment-friendly adhesive, maintain again the good comprehensive serviceability of this drug and food composite packing film simultaneously, thus improve the production technology quality grade of this compound soft packing material product well, achieve good environment protection modification effect.
In above-mentioned cold stamping solid medicinal composite hard sheet, as preferably, the binding agent of described adhesive layer obtains by following method: make solvent with acetone, add chloroethylene-vinyl acetate-maleic acid terpolymer resin as main body adhesion substance, be stirred in the temperature range of 55-65 DEG C and dissolve completely, add copolymer and polyurethane, Merlon, the polyestercarbonate of ethylene glycol-dimethyltrimethylene glycol-terephthalate-last of the ten Heavenly stems diester again, mix and form.
Compared with prior art, the present invention has the following advantages:
1, inter-layer bonding force increases, and steam, OTR oxygen transmission rate reduce, and barrier property increases, and global formation performance improves; Can stable prod quality, extend product service life and improving product security performance.
2, the maleic anhydride modified polyethylene layer extruded by coextrusion mode and acrylic acid modified polyethylene layer, not only have, with aluminium foil layer accompanying separately, aramid layer, there is higher peel strength, and whole extruding layer is soft, toughness is strong, have high hot strength and elongation at break, the aluminium that can effectively prevent product from may occur in cold stamping process splits and the problems such as absciss layer.
3, aluminum foil material is on the basis of 8011 alloys, component and content thereof are optimized, reduce Si constituent content, improve the content of Mn element, the intensity of material can be improved, simultaneously again with the Fe element of high-load, reduce the degree of supersaturation of Mn in aluminium, reduce the microsegregation of Mn, avoid the phenomenon of aluminium foil grain growth when homogenizing annealing, and reasonable compatibility other elements and content thereof, gather the advantage of 8011 alloys, not only increase aluminium foil intensity, rupture strength, also improve the rolling stability of aluminium foil simultaneously, production efficiency and yield rate, improve the surface quality of aluminium foil.
4, the binding agent of adhesive phase is by its composition of reasonable compatibility, composite interpolation polyurethane, Merlon, polyestercarbonate, improves the thermal property of binding agent and engineering properties and good tack, and ensures the impact of binding agent and the balance of mobility.
Accompanying drawing explanation
Fig. 1 is structural representation of the present invention.
In figure, 1, aramid layer; 2, aluminium foil layer; 3, polyvinyl chloride layer; 4, dry multiple glue layer; 5, urethane resin layer; 6, maleic anhydride modified polyethylene layer; 7, acrylic acid modified polyethylene layer; 8, adhesive layer.
Detailed description of the invention
Be below specific embodiments of the invention and by reference to the accompanying drawings, technical scheme of the present invention is further described, but the present invention be not limited to these embodiments.
As shown in Figure 1, this cold stamping solid medicinal composite hard sheet comprises the aramid layer 1 set gradually, aluminium foil layer 2, polyvinyl chloride layer 3, a dry multiple glue layer 4 is provided with between aluminium foil layer 2 and described polyvinyl chloride layer 3, the surface of aluminium foil layer 2 comprises aluminum phosphate film and rough layer, be coated with urethane resin layer 5 on aluminium foil layer 2 surface and described urethane resin layer 5 between aluminium foil layer 2 and aramid layer 1, maleic anhydride modified polyethylene layer 6 and acrylic acid modified polyethylene layer 7 is also disposed with between described aramid layer 1 and described aluminium foil layer 2, acrylic acid modified polyethylene layer 7 and urethane resin layer 5, adhesive layer 8 is equipped with between aluminium foil layer 2 and urethane resin layer 5, the density of described dry multiple glue layer 4 glue is 4.9-5.1g/cm
3, the thickness of described aramid layer 1 is 28-32 μm, and the thickness of aluminium foil layer 2 is 48-53 μm, and the thickness of polyvinyl chloride layer 3 is 52-58 μm, and the gross thickness of described cold stamping solid medicinal composite hard sheet is 140-143 μm.
The maleic anhydride modified polyethylene layer 6 extruded by coextrusion mode and acrylic acid modified polyethylene layer 7, not only have, with aluminium foil layer 2 accompanying separately, aramid layer 1, there is higher peel strength, and whole extruding layer is soft, toughness is strong, have high hot strength and elongation at break, the aluminium that can effectively prevent product from may occur in cold stamping process splits and the problems such as absciss layer.
Wherein, cold stamping solid medicinal composite hard sheet of the present invention adopts the aluminium foil of specific materials, and composition and the percentage by weight of described aluminium foil layer aluminum foil material are: Si:0.35-0.50%, Fe:0.9-1.20%, Cu:0.05-0.12%, Mn:0.50-0.60%, Mg:0.02-0.05%, Cr:0.02-0.05%, Zn:0.02-0.05%, Ti:0.02-0.05%, surplus are Al.
And make by following steps method:
S1, melting, casting: according to described in above-mentioned aluminium foil composition and percentage by weight take raw material, the raw material taken is carried out melting at 730-760 DEG C, then carries out casting and obtain blank, the sotck thinkness after casting is 7.2 ± 0.3mm;
S2, homogenizing annealing: above-mentioned blank is carried out homogenizing annealing process at 560-580 DEG C, come out of the stove after isothermal holding 18-23 hour and be cooled to normal temperature;
S3, cold rolling: cooled blank to be carried out cold rolling, then under 320-380 DEG C of condition, carries out intermediate annealing, be incubated obtained aluminium foil after 25-28 hour.
In addition, described in cold stamping solid medicinal composite hard sheet of the present invention, the binding agent of adhesive phase is made up of each component of following weight percentage: acetone: 25-32%; Chloroethylene-vinyl acetate-maleic acid terpolymer resin: 18-25%; The copolymer of ethylene glycol-dimethyltrimethylene glycol-terephthalate-last of the ten Heavenly stems diester: 30-40%; Polyurethane: 5-10%; Merlon: 5-10%; Polyestercarbonate: 5-10%.
The binding agent of described adhesive phase obtains by following method: make solvent with ketones solvent, add chloroethylene-vinyl acetate-maleic acid terpolymer resin as main body adhesion substance, be stirred in the temperature range of 55-65 DEG C and dissolve completely, add copolymer and polyurethane, Merlon, the polyestercarbonate of ethylene glycol-dimethyltrimethylene glycol-terephthalate-last of the ten Heavenly stems diester again, mix and form.
Embodiment 1
A kind of cold stamping solid medicinal composite hard sheet comprises the aramid layer 1 set gradually, aluminium foil layer 2, polyvinyl chloride layer 3, a dry multiple glue layer 4 is provided with between aluminium foil layer 2 and described polyvinyl chloride layer 3, the surface of aluminium foil layer 2 comprises aluminum phosphate film and rough layer, be coated with urethane resin layer 5 on aluminium foil layer 2 surface and described urethane resin layer 5 between aluminium foil layer 2 and aramid layer 1, maleic anhydride modified polyethylene layer 6 and acrylic acid modified polyethylene layer 7 is also disposed with between described aramid layer 1 and described aluminium foil layer 2, acrylic acid modified polyethylene layer 7 and urethane resin layer 5, adhesive layer 8 is equipped with between aluminium foil layer 2 and urethane resin layer 5, the density of described dry multiple glue layer 4 glue is 5.0g/cm
3, the thickness of described aramid layer 1 is 30 μm, and the thickness of aluminium foil layer 2 is 50 μm, and the thickness of polyvinyl chloride layer 3 is 55 μm, and the gross thickness of described cold stamping solid medicinal composite hard sheet is 142 μm.
Wherein, described aluminium foil obtains by the following method:
Melting, casting: according to described in following aluminium foil composition and percentage by weight take raw material: Si:0.40%, Fe:1.10%, Cu:0.08%, Mn:0.55%, Mg:0.03%, Cr:0.03%, Zn:0.03%, Ti:0.03%, surplus are Al, the raw material taken is carried out melting at 740 DEG C, then carry out casting and obtain blank, the sotck thinkness after casting is 7.2mm;
Homogenizing annealing: above-mentioned blank is carried out homogenizing annealing process at 570 DEG C, isothermal holding is come out of the stove after 20 hours and is cooled to normal temperature;
Cold rolling: cooled blank is carried out cold rolling, then under 360 DEG C of conditions, carry out intermediate annealing, be incubated obtained aluminium foil after 26 hours.
The binding agent of described adhesive phase obtains by the following method: make solvent with acetone, add chloroethylene-vinyl acetate-maleic acid terpolymer resin as main body adhesion substance, be stirred in the temperature range of 60 DEG C and dissolve completely, add copolymer and polyurethane, Merlon, the polyestercarbonate of ethylene glycol-dimethyltrimethylene glycol-terephthalate-last of the ten Heavenly stems diester again, mix and form.Wherein, binding agent is made up of each component of following weight percentage: acetone: 25%; Chloroethylene-vinyl acetate-maleic acid terpolymer resin: 25%; The copolymer of ethylene glycol-dimethyltrimethylene glycol-terephthalate-last of the ten Heavenly stems diester: 30%; Polyurethane: 10%; Merlon: 5%; Polyestercarbonate: 5%.
Embodiment 2
A kind of cold stamping solid medicinal composite hard sheet comprises the aramid layer 1 set gradually, aluminium foil layer 2, polyvinyl chloride layer 3, a dry multiple glue layer 4 is provided with between aluminium foil layer 2 and described polyvinyl chloride layer 3, the surface of aluminium foil layer 2 comprises aluminum phosphate film and rough layer, be coated with urethane resin layer 5 on aluminium foil layer 2 surface and described urethane resin layer 5 between aluminium foil layer 2 and aramid layer 1, maleic anhydride modified polyethylene layer 6 and acrylic acid modified polyethylene layer 7 is also disposed with between described aramid layer 1 and described aluminium foil layer 2, acrylic acid modified polyethylene layer 7 and urethane resin layer 5, adhesive layer 8 is equipped with between aluminium foil layer 2 and urethane resin layer 5, the density of described dry multiple glue layer 4 glue is 4.9g/cm
3, the thickness of described aramid layer 1 is 32 μm, and the thickness of aluminium foil layer 2 is 48 μm, and the thickness of polyvinyl chloride layer 3 is 58 μm, and the gross thickness of described cold stamping solid medicinal composite hard sheet is 143 μm.
Wherein, described aluminium foil obtains by the following method:
Melting, casting: according to described in following aluminium foil composition and percentage by weight take raw material: Si:0.35%, Fe:1.20%, Cu:0.05%, Mn:0.60%, Mg:0.02%, Cr:0.05%, Zn:0.02%, Ti:0.05%, surplus are Al, the raw material taken is carried out melting at 730 DEG C, then carry out casting and obtain blank, the sotck thinkness after casting is 7.5mm;
Homogenizing annealing: above-mentioned blank is carried out homogenizing annealing process at 580 DEG C, isothermal holding is come out of the stove after 18 hours and is cooled to normal temperature;
Cold rolling: cooled blank is carried out cold rolling, then under 380 DEG C of conditions, carry out intermediate annealing, be incubated obtained aluminium foil after 25 hours.
The binding agent of described adhesive phase obtains by the following method: make solvent with acetone, add chloroethylene-vinyl acetate-maleic acid terpolymer resin as main body adhesion substance, be stirred in the temperature range of 65 DEG C and dissolve completely, add copolymer and polyurethane, Merlon, the polyestercarbonate of ethylene glycol-dimethyltrimethylene glycol-terephthalate-last of the ten Heavenly stems diester again, mix and form.Wherein, binding agent is made up of each component of following weight percentage: acetone: 32%; Chloroethylene-vinyl acetate-maleic acid terpolymer resin: 18%; The copolymer of ethylene glycol-dimethyltrimethylene glycol-terephthalate-last of the ten Heavenly stems diester: 30%; Polyurethane: 5%; Merlon: 5%; Polyestercarbonate: 10%.
Embodiment 3
A kind of cold stamping solid medicinal composite hard sheet comprises the aramid layer 1 set gradually, aluminium foil layer 2, polyvinyl chloride layer 3, a dry multiple glue layer 4 is provided with between aluminium foil layer 2 and described polyvinyl chloride layer 3, the surface of aluminium foil layer 2 comprises aluminum phosphate film and rough layer, be coated with urethane resin layer 5 on aluminium foil layer 2 surface and described urethane resin layer 5 between aluminium foil layer 2 and aramid layer 1, maleic anhydride modified polyethylene layer 6 and acrylic acid modified polyethylene layer 7 is also disposed with between described aramid layer 1 and described aluminium foil layer 2, acrylic acid modified polyethylene layer 7 and urethane resin layer 5, adhesive layer 8 is equipped with between aluminium foil layer 2 and urethane resin layer 5, the density of described dry multiple glue layer 4 glue is 5.1g/cm
3, the thickness of described aramid layer 1 is 28 μm, and the thickness of aluminium foil layer 2 is 53 μm, and the thickness of polyvinyl chloride layer 3 is 52 μm, and the gross thickness of described cold stamping solid medicinal composite hard sheet is 140 μm.
Wherein, described aluminium foil obtains by the following method:
Melting, casting: according to described in following aluminium foil composition and percentage by weight take raw material: Si:0.35%, Fe:1.20%, Cu:0.05%, Mn:0.60%, Mg:0.02%, Cr:0.05%, Zn:0.02%, Ti:0.05%, surplus are Al, the raw material taken is carried out melting at 730 DEG C, then carry out casting and obtain blank, the sotck thinkness after casting is 7.5mm;
Homogenizing annealing: above-mentioned blank is carried out homogenizing annealing process at 580 DEG C, isothermal holding is come out of the stove after 18 hours and is cooled to normal temperature;
Cold rolling: cooled blank is carried out cold rolling, then under 380 DEG C of conditions, carry out intermediate annealing, be incubated obtained aluminium foil after 25 hours.
The binding agent of described adhesive phase obtains by the following method: make solvent with acetone, add chloroethylene-vinyl acetate-maleic acid terpolymer resin as main body adhesion substance, be stirred in the temperature range of 65 DEG C and dissolve completely, add copolymer and polyurethane, Merlon, the polyestercarbonate of ethylene glycol-dimethyltrimethylene glycol-terephthalate-last of the ten Heavenly stems diester again, mix and form.Wherein, binding agent is made up of each component of following weight percentage: acetone: 32%; Chloroethylene-vinyl acetate-maleic acid terpolymer resin: 18%; The copolymer of ethylene glycol-dimethyltrimethylene glycol-terephthalate-last of the ten Heavenly stems diester: 30%; Polyurethane: 5%; Merlon: 5%; Polyestercarbonate: 10%.
Cold stamping solid medicinal composite hard sheet adopts the rational aluminum foil material of compatibility to make aluminium foil layer, employing compatibility is rational, adhesive phase made by the binding agent of composite interpolation polyurethane, Merlon, polyestercarbonate, which floor hyaline membrane is after compound, and whole structure is still transparent, has high barrier property to steam and oxygen, and inter-layer bonding force increases, steam, OTR oxygen transmission rate reduce, and barrier property increases, and global formation performance improves; Can stable prod quality, extend product service life and improving product security performance.
Specific embodiment described herein is only to the explanation for example of the present invention's spirit.Those skilled in the art can make various amendment or supplement or adopt similar mode to substitute to described specific embodiment, but can't depart from spirit of the present invention or surmount the scope that appended claims defines.
Claims (5)
1. a cold stamping solid medicinal composite hard sheet, comprise the aramid layer set gradually, aluminium foil layer, polyvinyl chloride layer, a dry multiple glue layer is provided with between described aluminium foil layer and described polyvinyl chloride layer, it is characterized in that, the surface of described aluminium foil layer comprises aluminum phosphate film and rough layer, aluminium foil layer surface be coated with urethane resin layer and described urethane resin layer between aluminium foil layer and aramid layer, maleic anhydride modified polyethylene layer and acrylic acid modified polyethylene layer is also disposed with between described aramid layer and described aluminium foil layer, described acrylic acid modified polyethylene layer and described urethane resin layer, adhesive layer is equipped with between aluminium foil layer and urethane resin layer, the density of described dry multiple glue layer glue is 4.9-5.1g/cm
3, the thickness of described aramid layer is 28-32 μm, and the thickness of aluminium foil layer is 48-53 μm, and the thickness of polyvinyl chloride layer is 52-58 μm, and the gross thickness of described cold stamping solid medicinal composite hard sheet is 140-143 μm.
2. cold stamping solid medicinal composite hard sheet according to claim 1, it is characterized in that, composition and the percentage by weight of described aluminium foil layer aluminum foil material are: Si:0.35-0.50%, Fe:0.9-1.20%, Cu:0.05-0.12%, Mn:0.50-0.60%, Mg:0.02-0.05%, Cr:0.02-0.05%, Zn:0.02-0.05%, Ti:0.02-0.05%, Al surplus.
3. cold stamping solid medicinal composite hard sheet according to claim 2, is characterized in that, described aluminium foil obtains by the following method:
S1, melting, casting: according to described in aluminium foil composition and percentage by weight take raw material, the raw material taken is carried out melting at 730-760 DEG C, then carries out casting and obtain blank, the sotck thinkness after casting is 7.2 ± 0.3mm;
S2, homogenizing annealing: above-mentioned blank is carried out homogenizing annealing process at 560-580 DEG C, come out of the stove after isothermal holding 18-23 hour and be cooled to normal temperature;
S3, cold rolling: cooled blank is carried out cold rolling, during rolling the first passage, working modulus is 60-80%, and back pass working modulus remains on 35-45%, under 320-380 DEG C of condition, intermediate annealing is carried out to 0.6-0.8mm, insulation 25-28 hour through 5-6 passes;
S4, paper tinsel roll, by the aluminum strip after intermediate annealing through the aluminium foil of 2-3 passes to 0.20-0.26mm thickness.
4. cold stamping solid medicinal composite hard sheet according to claim 1, is characterized in that, the binding agent of described adhesive layer is made up of each component of following weight percentage: acetone: 25-32%; Chloroethylene-vinyl acetate-maleic acid terpolymer resin: 18-25%; The copolymer of ethylene glycol-dimethyltrimethylene glycol-terephthalate-last of the ten Heavenly stems diester: 30-40%; Polyurethane: 5-10%; Merlon: 5-10%; Polyestercarbonate: 5-10%.
5. cold stamping solid medicinal composite hard sheet according to claim 4, it is characterized in that, the binding agent of described adhesive layer obtains by the following method: make solvent with acetone, add chloroethylene-vinyl acetate-maleic acid terpolymer resin as main body adhesion substance, be stirred in the temperature range of 55-65 DEG C and dissolve completely, add copolymer and polyurethane, Merlon, the polyestercarbonate of ethylene glycol-dimethyltrimethylene glycol-terephthalate-last of the ten Heavenly stems diester again, mix and form.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107475574A (en) * | 2017-09-22 | 2017-12-15 | 马鞍山松鹤信息科技有限公司 | A kind of compound aluminium product and its preparation technology |
| CN109664573A (en) * | 2018-12-25 | 2019-04-23 | 常州市华健药用包装材料股份有限公司 | A kind of cold stamping shaped composite hard sheet of printable high-intensitive solid medicinal |
| CN110435271A (en) * | 2018-05-03 | 2019-11-12 | 南通惠得成包装材料有限公司 | A kind of composite hard sheet and production method |
| CN115073862A (en) * | 2022-07-09 | 2022-09-20 | 浙江多凌药用包装材料有限公司 | Production process of anti-aging PVC (polyvinyl chloride) hard sheet |
Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1597310A (en) * | 2004-08-11 | 2005-03-23 | 刘继福 | High sealing cold punching press shaped bubble cup plustic aluminium composite hard sheet and its production technology |
| CN101024325A (en) * | 2007-02-06 | 2007-08-29 | 徐小圣 | Technology for preparing high-separation, low solvent residue and low resolving-out matter PVC/PE/PVCD solid medicinal composite hard sheet |
| CN200954706Y (en) * | 2006-05-12 | 2007-10-03 | 常州市华健药用包装有限公司 | Cold-punching formed solid medicine-use composite hard sheet |
| CN101428700A (en) * | 2008-12-16 | 2009-05-13 | 常州市华健药用包装有限公司 | Composite hard tablet for packaging chinese medicine |
| EP2156946A1 (en) * | 2008-08-20 | 2010-02-24 | Riken Technos Corporation | Multi-layer film |
| CN202037934U (en) * | 2011-03-07 | 2011-11-16 | 苏州海顺包装材料有限公司 | Cold stamping molded compound hard sheet for packing medicaments |
| CN102329984A (en) * | 2011-06-14 | 2012-01-25 | 刘继福 | Aluminum foil material capable of meeting more than 4 mm punching depth of cold punch formed flexible package material |
| CN202399599U (en) * | 2011-12-20 | 2012-08-29 | 常州市华健药用包装材料有限公司 | Cold stamping forming medicinal composite hard sheet |
| CN203567291U (en) * | 2013-11-25 | 2014-04-30 | 宁波龙安包装科技有限公司 | Cold stamped solid medicine composite hard sheet |
| CN104228214A (en) * | 2013-12-24 | 2014-12-24 | 刘启 | Medicinal symmetrical cold-forming aluminum-casting plate |
-
2014
- 2014-12-31 CN CN201410852827.5A patent/CN104589728B/en active Active
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1597310A (en) * | 2004-08-11 | 2005-03-23 | 刘继福 | High sealing cold punching press shaped bubble cup plustic aluminium composite hard sheet and its production technology |
| CN200954706Y (en) * | 2006-05-12 | 2007-10-03 | 常州市华健药用包装有限公司 | Cold-punching formed solid medicine-use composite hard sheet |
| CN101024325A (en) * | 2007-02-06 | 2007-08-29 | 徐小圣 | Technology for preparing high-separation, low solvent residue and low resolving-out matter PVC/PE/PVCD solid medicinal composite hard sheet |
| EP2156946A1 (en) * | 2008-08-20 | 2010-02-24 | Riken Technos Corporation | Multi-layer film |
| CN101428700A (en) * | 2008-12-16 | 2009-05-13 | 常州市华健药用包装有限公司 | Composite hard tablet for packaging chinese medicine |
| CN202037934U (en) * | 2011-03-07 | 2011-11-16 | 苏州海顺包装材料有限公司 | Cold stamping molded compound hard sheet for packing medicaments |
| CN102329984A (en) * | 2011-06-14 | 2012-01-25 | 刘继福 | Aluminum foil material capable of meeting more than 4 mm punching depth of cold punch formed flexible package material |
| CN202399599U (en) * | 2011-12-20 | 2012-08-29 | 常州市华健药用包装材料有限公司 | Cold stamping forming medicinal composite hard sheet |
| CN203567291U (en) * | 2013-11-25 | 2014-04-30 | 宁波龙安包装科技有限公司 | Cold stamped solid medicine composite hard sheet |
| CN104228214A (en) * | 2013-12-24 | 2014-12-24 | 刘启 | Medicinal symmetrical cold-forming aluminum-casting plate |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107475574A (en) * | 2017-09-22 | 2017-12-15 | 马鞍山松鹤信息科技有限公司 | A kind of compound aluminium product and its preparation technology |
| CN110435271A (en) * | 2018-05-03 | 2019-11-12 | 南通惠得成包装材料有限公司 | A kind of composite hard sheet and production method |
| CN109664573A (en) * | 2018-12-25 | 2019-04-23 | 常州市华健药用包装材料股份有限公司 | A kind of cold stamping shaped composite hard sheet of printable high-intensitive solid medicinal |
| CN109664573B (en) * | 2018-12-25 | 2020-07-17 | 常州市华健药用包装材料股份有限公司 | Printable high-strength solid medicinal cold stamping forming composite hard sheet |
| CN115073862A (en) * | 2022-07-09 | 2022-09-20 | 浙江多凌药用包装材料有限公司 | Production process of anti-aging PVC (polyvinyl chloride) hard sheet |
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