CN104586349B - Eye temperature measuring and analyzing system, receiving and analyzing device and method thereof - Google Patents
Eye temperature measuring and analyzing system, receiving and analyzing device and method thereof Download PDFInfo
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- Measuring And Recording Apparatus For Diagnosis (AREA)
- Eye Examination Apparatus (AREA)
Abstract
A system for measuring and analyzing the temperature of an eye is used to measure, record and analyze the surface temperature of the eye. The system comprises an eye temperature measuring device and a receiving and analyzing device. The eye temperature measuring device comprises a temperature sensing component and a signal transmission component, and the data of the surface temperature of the eye measured by the temperature sensing component is transmitted to the outside through the signal transmission component. The receiving and analyzing device comprises a signal receiving unit and an analyzing unit, wherein the signal receiving unit receives the wireless signal, and the analyzing unit analyzes and judges whether the surface temperature of the eyes is normal or not according to the wireless signal.
Description
Technical field
The present invention is on a kind of measurement of eye temperature and analysis system, receiving analyzer and its method, especially
On a kind of system, analytical equipment and its method for being used to analyzing and judging ocular surface temperature.
Background technology
The surface temperature of eyes is the state of each portion's muscle or each layer tissue that react eyeball, therefore can be good for as eyes are represented
A kind of important indicator of health or lesion.When eyes are in inflammation or have muscle regulation nervous (spasm), ocular temperature will
Increase, for example:Ciliary spasm causes myopia, and ocular temperature can be caused to raise.However, for patients with dry eye,
Between eyelid folding, because the quantity that tear flows to ocular is reduced, the reduction of ocular temperature can be caused.Therefore, the liter of ocular temperature
High or reduction can be used for judging whether eyes are healthy, close to lesion or occur lesion.
D.M.Maurice and A.S.Mushin is in write paper " Production of Myopia in Rabbits by
Raised Body-Temperature and Increased Intraocular Pressure”(The Lancet;
November 26,1966, pp.1160-1162) in point out:When the body temperature of young rabbit is raised to 41-43 DEG C, about 30 are maintained
After minute, the refractive diopter (dioptres) of rabbit will reach more than -0.75.Near-sighted the reason for is exactly ophthalmic refractive ability
It is too big, cause the parallel rays parallel to the optical axis to converge in before retina, it is impossible to be formed clearly be imaged on the retina.Again
Person, the change of the optical axis also has positive correlation with eyeball temperature.Because the spasm of ciliary muscle may stimulate the elongation of the eyeball optical axis, so that
The true myopia that can not be reversed is formed, this paper is also proved to the relevance of eyeball temperature and myopia or eyeball change.Work as eye
The temperature of ball rises, and spheroid can inherently expand.The strength of eyeball perienchyma resistance expansion is stronger again, therefore the expansion is just passed
Toward the development of eyeball bottom.Eyeball accumulates over a long period under this improper deformation and has resulted in a longer eyeball of the optical axis.
Tien-Chun Chang, wait write paper " Application of digital infrared thermal again
imaging in determining inflammatory state and follow-up effect of
methylprednisolone pulse therapy in patients with Graves’ophthalmopathy”
(Graefes Arch Clin Exp Ophthalmol;2008,246 vol., pp.45-49) in point out:For Ge Leifushi
Disease (Graves ') can effectively assist to observe and record eyeball with the local temperature of computerization far-infrared thermal radiographic measurement
Inflammation degree.Paper " the The application of temperature in addition, hyang-Rong Shih etc. write
measurement of the eyes by digital infrared thermal imaging as a prognostic
factor of methylprednisolone pulse therapy for Graves’ophthalmopathy”(Acta
Ophthalmologica;2010 vol.88, pp.164-159) it can learn:Eye temperature is put down after heavy dose of steroid therapy
It can decline for, the eye temperature before the degree of temperature drop and treatment is into positive correlation.These researchs show far-infrared thermal
The temperature survey of image helps to predict the effect that heavy dose of steroid therapy thyroid eye diseas becomes.
In addition, because the electronic building brick of different purposes is constantly miniaturized, for head-wearing type or embedded medical (or correction)
The application that device integrates the grade electronic building brick is also more and more.For example:United States Patent (USP) US2012/0245444 proposes a kind of combine
Biochip head-wearing type contact lenses, to detect before cornea the particular chemicals concentration in (tear) film.And United States Patent (USP)
US2010/0234717, US2013/0041245 and pct international patent WO03/001991 propose a kind of contact lenses combination electronics
Pressure sensor, to measure intra-ocular pressure power.So fresh few patent or document propose contact lenses combination electronic temperature transmitter
To measure the surface temperature of eyes, more lacking related preceding case has the open contact lenses using tool temperature measurement function to judge eye
The technology contents of eyeball health or lesion.
In summary, eyes medical treatment or vision correction are needed badly and want a kind of and can judge system and the side of eye health or lesion
Method, it is possible thereby to be widely used in preventive medicine and correction monitoring.
The content of the invention
It is an object of the invention to provide a kind of measurement of eye temperature and analysis system, receiving analyzer and its method,
It is by recording the data of ocular surface temperature so that analyze and judge eyes whether health, close to lesion or occurred disease
Become, therefore preventive medicine and correction monitoring can be used for.
For up to above-mentioned purpose, the present invention provides measurement and the analysis system of a kind of eye temperature, comprising:
One eyes temperature measuring equipment, is placed in eyeball surface, including:
One temperature sensing component, electric signal is produced according to ocular surface temperature;And
One signal transfer assembly, is wireless signal by the transform electric;And
One receiving analyzer, including:
One signal receiving unit, receives the wireless signal;And
One analytic unit, according to the wireless signal analysis and judges whether the ocular surface temperature is normal.
The measurement of foregoing eye temperature and analysis system, wherein, the eye temperature measurement apparatus is additionally comprised one day
Line, the antenna transmits the wireless signal to outside.
The measurement of foregoing eye temperature and analysis system, wherein, the antenna is by outside electromagnetic waveforms into electricity
Sense coupling and produce electric power, for should temperature sensing component and the signal transfer assembly.Wherein, it additionally comprises an outside day
Line, the exterior antenna can turn to pass the wireless signal.
The measurement of foregoing eye temperature and analysis system, wherein, the wireless signal be meet radio frequency, bluetooth or
The signal of WiFi defineds.
The measurement of foregoing eye temperature and analysis system, wherein, the analytic unit is according to the ocular surface
One temperature value, between the temperature value at two time points difference or in continuous multiple time points temperature value average value or its change with
Judge whether eyes have the generation of lesion.Wherein, when the eyes surface temperature nocturnal temperature and daytime temperature difference it is low
In a lower limit, then generation of the eyes without myopia or pseudo-myopia is judged.Wherein, the difference is between the lower limit and a higher limit
Between, then judge that eyes there may be the generation of myopia or pseudo-myopia.Wherein, the difference is more than the higher limit, then judges eyes
There is the generation of myopia or pseudo-myopia.
The measurement of foregoing eye temperature and analysis system, wherein, when the temperature measured between two time points of the eyes
Angle value difference is less than a lower limit, then judges that eyes should have the generation of xerophthalmia.Wherein, the temperature value of two point in time measurement is
Ocular surface is measured again between the 6th to 10 second after blink opening eyelid measures ocular surface temperature and this time measurement immediately
Temperature, and the eyelid is persistently to open between this is measured twice.Wherein, when the temperature value measured between two time points of the eyes
When difference is between 0.2 DEG C to 0.4 DEG C, then judge that eyes there may be the generation of xerophthalmia.Wherein, when twice of the eyes
When the temperature value difference measured between point is more than 0.4 DEG C, then judge that the probability of eyes generation xerophthalmia is low.
The measurement of foregoing eye temperature and analysis system, wherein, the receiving analyzer is one to have installed specific
Software or the computer of application program, a tablet PC, an intelligent mobile phone or a smart watch.
The measurement of foregoing eye temperature and analysis system, wherein, the signal receiving unit includes:
One portable askes answers unit there is provided the electric power needed for the signal transfer assembly and the temperature sensing component, and receives
The wireless signal is to produce radiofrequency signal;And
One data receipt unit, receives the radiofrequency signal to be converted to the data with ocular surface temperature.Wherein, this point
It is a computer to analyse unit.
The measurement of foregoing eye temperature and analysis system, wherein, the temperature sensing component is provided at contact lenses
Surface on multiple ring-type circuits, special applications IC or electric component of microcomputer.
The measurement of foregoing eye temperature and analysis system, wherein, the eye temperature measurement apparatus is one with temperature
The contact lenses of degree measurement function.
The measurement of foregoing eye temperature and analysis system, wherein, the eye temperature measurement apparatus is placed in eyeball
To measure the temperature of eyes on the inside of surface and eyelid, and its size does not cover pupil.
The present invention separately provides a kind of receiving analyzer of eye temperature, comprising:
One signal receiving unit, receives a wireless signal, and the wherein wireless signal includes the data of ocular surface temperature;With
And
One analytic unit, according to the wireless signal analysis and judges whether the ocular surface temperature is normal.
The receiving analyzer of foregoing eye temperature, wherein, the analytic unit is the temperature according to ocular surface
Value, between the temperature value at two time points difference or in continuous multiple time points temperature value average value or its change to judge eye
Whether eyeball has the generation of lesion.Wherein, when the nocturnal temperature of surface temperature and the difference of daytime temperature of the eyes are less than once
Limit value, then judge generation of the eyes without myopia or pseudo-myopia.Wherein, the difference is between the lower limit and a higher limit,
Then judge that eyes there may be the generation of myopia or pseudo-myopia.Wherein, the difference is more than the higher limit, then judges that eyes have myopia
Or the generation of pseudo-myopia.
The receiving analyzer of foregoing eye temperature, wherein, when the temperature measured between two time points of the eyes
Value difference is different to be less than a lower limit, then judges that eyes should have the generation of xerophthalmia.Wherein, the temperature value of two point in time measurement be in
Blink open eyelid measure immediately ocular surface temperature and this time measurement after the 6th to 10 second between measure ocular surface temperature again
Degree, and the eyelid is persistently to open between this is measured twice.Wherein, when the temperature value difference measured between two time points of the eyes
It is different between 0.2 DEG C to 0.4 DEG C when, then judge that eyes may have the generation of xerophthalmia.Wherein, when two time points of the eyes
Between the temperature value difference that measures when being more than 0.4 DEG C, then judge that the probability of eyes generation xerophthalmia is low.
The receiving analyzer of foregoing eye temperature, wherein, the signal receiving unit includes:
One portable askes answers unit, receives the wireless signal to produce radiofrequency signal;And
One data receipt unit, receives the radiofrequency signal to be converted to the data with ocular surface temperature.Wherein, this point
It is a computer to analyse unit.
The receiving analyzer of foregoing eye temperature, wherein, the receiving analyzer is one to have installed specific soft
Part or the computer of application program, a tablet PC, an intelligent mobile phone or a smart watch.
The present invention provides measurement and the analysis method of a kind of eye temperature, and it is comprised the steps of:
The surface temperature of eyes is measured by an eye temperature measurement apparatus for being placed in eyeball surface;
The data of the surface temperature are transmitted with wireless signal;
Receive the wireless signal;And
According to the wireless signal analysis and judge whether the surface temperature of the eyes is normal.
The measurement of foregoing eye temperature and analysis method, wherein, the wireless signal be meet radio frequency, bluetooth or
The signal of WiFi defineds.
The measurement of foregoing eye temperature and analysis method, wherein, the analysis and further include the step of judge
The average value of difference or the temperature value in continuous multiple time points according to a temperature value of eyes, between the temperature value at two time points
Or its change, to judge whether eyes have the generation of lesion.Wherein, the difference be less than a lower limit, then judge eyes should have or
Should the generation without lesion.Wherein, the difference judges that eyes may have the hair of lesion between the lower limit and a higher limit, then
It is raw.Wherein, the difference is more than the higher limit, then judges that eyes should have or should the generation without lesion.
Brief description of the drawings
Fig. 1 is the broken line of the ocular surface of pseudo-myopia group and twenty-twenty vision group in table one in the daytime with nocturnal temperature difference
Figure;
Fig. 2 is the schematic diagram of eye temperature measurement apparatus of the present invention;
Fig. 3 is that Fig. 2 eye temperature measurement apparatus is attached to the schematic diagram of ocular surface;
Fig. 4 is measurement and the schematic diagram of analysis system of eye temperature of the present invention;
Fig. 5 be eye temperature of the present invention measurement and analysis system another embodiment schematic diagram;
Fig. 6 is the flow chart of the measurement and analysis method of eye temperature of the present invention;
Fig. 7 is the schematic diagram of another embodiment of eye temperature measurement apparatus of the present invention;
Fig. 8 is that Fig. 7 eye temperature measurement apparatus is attached to the schematic diagram of ocular surface.
Primary clustering symbol description:
20 contact lenses
21 transparent bases
22 temperature sensing components
23 antennas
24 signal transfer assemblies
30 eyeballs
40 systems
41 portable ask answer unit
42 data receipt units
43 computers
411 ring-type inductive loops
50 systems
51 mobile phones
52 desktop PCs
61~64 steps
70 eye temperature measurement apparatus
71 base materials
72 temperature sensing components
73 antennas
74 signal transfer assemblies
Embodiment
Simplification for displaying and clear, accompanying drawing illustrates overall make, and it is well known that feature and technology
Description and details can omit with avoid making the present invention unnecessarily obscure.In addition, the key element in accompanying drawing is not necessarily in size
Draw.For example, the size of some key elements in accompanying drawing can be exaggerated to help improve to the present invention's relative to other key elements
The understanding of embodiment.Same reference numbers in different figures represent identical key element.
Term "comprising", " comprising " and " having " and its any version in description and claims are intended to cover
Lid nonexcludability includes, so that a series of program including key elements, method, system, object, device or equipment are not necessarily limited
In those key elements, but it can include not listing clearly or such program, method, system, project, device or equipment are solid
The other key elements having.
As it was previously stated, ocular temperature is raised and lowered available for judging whether eyes are healthy, close to lesion or occurred
Lesion.Especially ciliary spasm can cause myopia, and cause the rise of ocular temperature.Following table one show pseudo-myopia group and
The data of the measurement ocular surface temperature of twenty-twenty vision group.
Table one
Medical literature is also noted that:When body temp rises (having a high fever) or the meeting of ocular surface temperature because eyes short distance
Something (books, TV, computer and mobile phone etc.) is stared at, especially short distance and long-time is watched attentively in an object, can cause eyelash
Shape flesh is chronically at the state of high-tension, because the presence of such a high-tension causes eyeball temperature with increase.Although daytime is long
The ciliary muscle of time is excessively used, but at night during sleep, ciliary muscle can relax gradually, therefore temperature should be able to slowly decline.Separately
On the one hand, because eyelid can be closed during sleep, therefore it is hindered to cause heat outwards to discharge, that is, eyeball temperature be still not easy or
It can not even decline.Meanwhile, during sleep because body posture change (for example lying low), the posture of eyeball also with change,
The pressure on the vitreum periphery of eyeball is caused more to raise, high temperature and high pressure are just by the internal position for being transmitted to eyeball bottom.Therefore
Easily cause length of the eyeball in boresight direction.Because same problem day by day occurs again and again, the optic axis length of eyeball is just not
It is disconnected elongated, so that imaging is formed before retina, that is, just produce myopia.
Fig. 1 is the broken line of the ocular surface of pseudo-myopia group and twenty-twenty vision group in table one in the daytime with nocturnal temperature difference
Figure.The ocular surface night of pseudo-myopia group and differing greatly for daytime temperature, that is, its ocular surface should be clear from by figure
Nocturnal temperature it is significantly higher.Review, the ocular surface night of twenty-twenty vision group and the difference of daytime temperature are smaller, that is, its eye
The nocturnal temperature on eyeball surface is more slightly higher.It therefore, it can by recording the data of ocular surface temperature, so as to analyze and judge eye
Eyeball whether health, close to lesion or occurred lesion, therefore preventive medicine and correction monitoring can be used for.The present invention is not limited only to myopia
The judgement of eye, the eye conditions of xerophthalmia or other presentation temperature changes are equally applicable for various embodiments of the present invention, or in response to
The amplitude of temperature change and direction suitably change the condition of each embodiment.Fig. 1 is that two crowds of people carry out eyes table in the daytime with night
The measurement of face temperature, the present invention can also be used to measure same people for a long time in difference in the daytime with the ocular surface temperature at night
Average value, or same people is measured in the maximum changing value or average value of the ocular surface temperature of daily same time point for a long time,
Or the difference and change of specific time period ocular surface temperature or specific time period mean temperature.Previous embodiment is not intended to limit this hair
Bright, the difference value or average value of long-time or short time ocular surface temperature can be applied to the present invention.
As it was previously stated, ocular temperature is raised and lowered available for judging whether eyes are healthy, close to lesion or occurred
Lesion.Especially xerophthalmia because tears hyposecretion can caused by cause ocular temperature obvious change.Following table two shows dry eyes
Disease patient population and without xerophthalmia person group measurement ocular surface temperature data.
Table two
To:Blink opens eyelid and measures ocular surface temperature immediately.
Tc:Eyes table is measured again in the 6th second (or selecting any time point between the 6th second to the 10th second) after To measurements
Face temperature, and eyelid is persistently to open between this is measured twice.
Td:It is To and Tc difference value.
From the contained numerical value of table two, the difference value Td of patients with dry eye group is substantially compared with the difference value Td without xerophthalmia person group
It is low.Therefore can be by this fact as the basis for judging xerophthalmia generation, and it is as follows to list judgment criterion:When the difference
When value Td is less than 0.2 DEG C, it is believed that eyes should have xerophthalmia;When difference value Td is between 0.2 DEG C~0.4 DEG C, it is believed that eye
Eyeball may have the occurrence risk of xerophthalmia;When the difference value is more than 0.4 DEG C, then it is believed that the probability of xerophthalmia occurs for eyes
It is low.The present invention is not limited by this embodiment, and it is accurate also directly can to make another judgement using temperature value To or Tc single numerical value
Then, or repeatedly the change (uprush, anticlimax, increasing or decreasing) of the curve that is formed of temperature value To or Tc or slope variation are made
Different judgment criterions.The content and deciding means of judgment criterion should actually be changed with different eye conditions.
Fig. 2 is the schematic diagram of eye temperature measurement apparatus of the present invention.The eye temperature measurement apparatus of this embodiment is a tool
There are the contact lenses 20 of temperature measurement function, but the present invention is not limited system, can be placed in eyeball surface to measure eyes
Any wearing apparatus of temperature.The contact lenses 20 are mainly comprising a transparent base 21, a temperature sensing component (or temperature sensing
Circuit) 22, one antenna 23 and a signal transfer assembly 24.The material of transparent base 21 can be silicon glue (silicone
Hydrogel, for example:HEMA), because having the advantages that high oxygen transmission rate and hydrophily, therefore the comfortableness of prestowage person can be improved, and fitted
Close and wear for a long time.The material of transparent base 21 can also be other transparent high polymer materials, not limited by this embodiment
System.The antenna 23 can send wireless signal to outside, can also be used to receive external energy, for example:By radiofrequency signal or
Other electromagnetic waves cause formation inductive (the inductive link or inductive coupling) effect of antenna 23, so that
Produce the electric power needed for the warm degree sensing component 22 of electric energy supply and signal transfer assembly 24.In addition, send radiofrequency signal or its
The power supply device of its electromagnetic wave can be arranged in scarf or be placed in pocket, or be integrated into other portable devices (examples
Such as:Mobile phone, blue-tooth earphone etc.) in.But the present embodiment is not limited system, one micro electronmechanical (MEMS) battery can also be located at
The surface of transparent base 21 or inside.
Due to being limited to the area of contact lenses 20, the period or size of the antenna 23 are also quite restricted.For that can mend
Repaying may be insufficient to the signal intensity of the antenna 23, (such as eye socket) separately can paste an exterior antenna around eyes,
Therefore by singal transduction and can strengthen, it can be understood with the signal receiver of profit remotely and received.
In order to observe temperature change of the eyeball at daytime and/or sleep for a long time, on the surface of transparent base 21 with stealthy eye
The center of mirror 20 is common center, is coated with the ring-type circuit (i.e. temperature sensing component 22) of several energy sensing temperatures, the ringed line
Road can be multiple circular annular form lines, polygonal ring shape line or irregular ringed line.The temperature sensing component 22 can be special
Using IC (Application-Specific IC;ASIC) or micro electronmechanical (MEMS) component, or with nm, gram (PECO)
Chemical material, metal material or the sensing component of biomaterial formation of grade, can be used for measurement temperature or reaction temperature changes.
The signal transfer assembly 24 can (such as voltage signal or electric current be believed by the electric signal produced by temperature sensing component 22 again
Number) radio frequency (RF) signal is converted to, and wireless signal is transmitted to outside by antenna 23.But the invention is not restricted to by electric signal
Radio frequency (RF) signal is converted to, the signal of the defined patterns such as bluetooth (Bluetooth) or WiFi can also be converted to.Before similar
Described ring-type circuit, antenna 23 is to be coated on the surface of transparent base 21 and in multiple ring-types of the periphery of temperature sensing component 22
Circuit, can send the wireless signal for meeting communication protocol to outside.
Fig. 3 is that Fig. 2 eye temperature measurement apparatus is attached to the schematic diagram of ocular surface.Will as illustrated, working as testee
Contact lenses 20 are placed in the surface of eyeball 30, because the temperature sensing component 22 and antenna 23 of the tool ring-type circuit be located at non-vision by
Light region, therefore the light into pupil will not be blocked, it can not only be worn during nighttime sleep, also be adapted for wearing in day's activities
And synchro measure.Such a contact lenses 20 with temperature measurement function are worn when can be long in normal life or work, by
Survey person need not be limited to temperature measuring tool and can only reside at tested region, for example:Positioned at red used in prior art
The front of outside line thermo detector, therefore activity, sleep or prolonged measurement are convenient to, so as to increase the correctness of judged result.
Fig. 4 is measurement and the schematic diagram of analysis system of eye temperature of the present invention.System 40 includes a contact lenses 20, one
Movable type is ask and answers unit (mobile interrogation unit) 41, one data receipt unit 42 and a computer 43.The shifting
Dynamic formula inquiry answers unit 41 and wirelessly provides the signal transfer assembly 24 and temperature sensing component by ring-type inductive loop 411
Electric power needed for 22, and include the wireless signal of ocular surface temperature data from the reception of antenna 23 of contact lenses 20, and should
Wireless signal is demodulated change to obtain the electric signal, and then the electric signal is simulated to numeral conversion to obtain one
The numerical data of the electric signal is relevant to, then the numerical data is subjected to modulation conversion and is loaded on a carrier wave to obtain a radio frequency
Signal.The data receipt unit 42 is ask from the movable type and answers unit 41 with the wireless receiving radiofrequency signal, and by the radiofrequency signal
Change is demodulated to obtain the numerical data that this is relevant to the electric signal.The numerical data of 43 internal memory of computer one and ocular surface
Temperature corresponding table, and the data receipt unit 42 is electrically connected to receive the numerical data, and table look-up to obtain an eyes according to this
Surface temperature, and shown and stored.
Computer 43 can be analyzed and stored ocular surface temperature data, and whether just judge the ocular surface temperature
Often.For example:Myopia or pseudo-myopia are determined whether using the difference (referring to table one) of ocular surface night and daytime temperature
Occur;When the difference value is less than 0.1 DEG C, it is believed that doubt of the eyes without myopia;When the difference value is between 0.1 DEG C~0.3 DEG C
When, it is believed that eyes may have myopia;When the difference value is more than 0.3 DEG C, then it is believed that eyes should have myopia.Before open judgement
As a result it can be shown on the screen of computer 43, or be presented with the color of the indicator lamp of data receipt unit 42, for example:Green generation
Doubt of the table without myopia, yellow, which represent the presence that may have myopia and red representative, the generation of myopia.The present invention is not by above-mentioned
The criterion limitation of embodiment, can be determined according to actual ocular surface temperature and different symptoms.
Movable type inquiry answers unit 41, data receipt unit 42 and data analysis and judges that (the present embodiment is by computer 43
It is responsible for) receiving analyzer can be integrated into, the receiving analyzer can one install specific software or application program
Computer, tablet PC, intelligent mobile phone or smart watch, also can be by ring-type inductive loop 411 and the grade device knot
Close or be embedded in the grade device.
Fig. 5 be eye temperature of the present invention measurement and analysis system another embodiment schematic diagram.System 50 is to use
Mobile phone 51 or desktop PC 52 as receiving analyzer, the receiving analyzer comprise at least a signal receiving unit and
One analytic unit, the signal receiving unit receives the wireless signal that contact lenses 20 are sent, and the analytic unit can be according to the nothing
Line signal analysis and judge whether the ocular surface temperature is normal.
Fig. 6 is the flow chart of the measurement and analysis method of eye temperature of the present invention.The present invention provides a kind of eye temperature
Measurement and analysis method, it is comprised the steps of:As shown at step 61, the contact lenses for having temperature measurement function by one are surveyed
Measure the surface temperature of eyes;As shown in step 62, the data of the surface temperature are transmitted with wireless signal;As shown at step 63, connect
By the wireless signal;As shown in step 64, and according to the wireless signal analysis and whether just the surface temperature of the eyes is judged
Often.
Contact lenses 20 compared to Fig. 3, Fig. 7 is the signal of another embodiment of eye temperature measurement apparatus of the present invention
Figure, when the eye temperature measurement apparatus 70 of this embodiment is worn on eyeball surface, does not cover pupil.In addition, this embodiment
Device be equally applicable in the measurement and analysis system of foregoing eye temperature, can also receive the portable electricity ask and answer unit 41
Power is supplied and transmits the wireless signal containing ocular surface temperature data.The eye temperature measurement apparatus 70 mainly includes a base material
71st, the antenna 73 of a temperature sensing component (or temperature sensing circuit) 72, one and a signal transfer assembly 74.The base material of the present embodiment
71 material can be silicon glue (silicone hydrogel) polyester (polyester) or polyacrylamide, light can be allowed to wear entirely
Thoroughly, the material for partly penetrating or not penetrating completely is suitable for.Base material 71 can also be made of other high polymer materials, soft or hard
Material is (for example:Poly- silicon-oxygen polymer, polymethyl methacrylate, need to coordinate eyeball radian to be molded), so not by this reality
Apply the limitation of example.The antenna 73 can send wireless signal to outside, can also be used to receive external energy, for example:By penetrating
Frequency signal or other electromagnetic waves cause the formation inductive of antenna 73 (inductive link or inductive coupling)
Effect, so as to produce the electric power needed for electric energy supply temperature sensing component 72 and signal transfer assembly 74.In addition, can be in base material 71
Surface sets a minicell, and its produced electric energy can be supplied directly needed for the warm degree sensing component 72 and signal transfer assembly 74
Electric power.
Because eye temperature measurement apparatus 70 is placed in eyelid (referring to Fig. 8), therefore its area may be restricted,
Also it is limited so as to the period or size of the antenna 73.The signal intensity of the antenna 73 may be insufficient to for that can compensate, can
With around eyes (such as eye socket) separately paste an exterior antenna, therefore by singal transduction and can strengthen, with the signal of profit remotely
Receiver, which can understand, to be received.
In order to observe temperature change of the eyeball at daytime and/or sleep for a long time, on the surface of base material 71, coating is several can sense
The ring-type circuit (i.e. temperature sensing component 72) of testing temperature, the ring-type circuit can be multiple circular annular form lines, polygonal ring shape
Line or irregular ringed line.The temperature sensing component 72 can be special applications IC (Application-Specific IC;
ASIC) or micro electronmechanical (MEMS) component, or with nm, the chemical material of gram (PECO) grade, metal material or biological material
Expect the sensing component formed, measurement temperature can be used for or reaction temperature changes.The signal transfer assembly 74 can be by temperature sense again
Electric signal (such as voltage signal or current signal) produced by surveying component 72 is converted to radio frequency (RF) signal, and passes through antenna
73 transmit wireless signal to outside.But the invention is not restricted to be radio frequency (RF) signal by transform electric, it can also be converted to
The signal of the defined pattern such as bluetooth (Bluetooth) or WiFi.Described ring-type circuit before similar, antenna 73 is to be coated on base
The surface of material 71 and in multiple ring-type circuits of the periphery of the temperature sensing component 72, will can meet the wireless signal of communication protocol to
Outside is sent.
Fig. 8 is the schematic diagram that eye temperature measurement apparatus of the present invention is attached to ocular surface.Will as illustrated, working as testee
Eye temperature measurement apparatus 70 is placed on the inside of the surface of eyeball 30 and eyelid (palpebra inferior or upper eyelid), because positioned at non-vision sensitive area
Domain event base material 71 can select opaque material, that is, be not required to consider whether that the light into pupil can be blocked, not only nighttime sleep
When can wear, also be adapted in day's activities wear and synchro measure.The shape of base material 71 can be half-moon-shaped as depicted
Or rectangle, it is placed in profit on the inside of eyelid.
The technology contents and technical characterstic of the present invention are disclosed as above, but one skilled in the art scholar is still potentially based on
Teachings of the present invention and open and make a variety of replacements and modification without departing substantially from spirit of the present invention.Therefore, protection scope of the present invention
Those disclosed embodiments should be not limited to, and various replacements and modification without departing substantially from the present invention should be included, and are contained by claim
Lid.
Claims (29)
1. measurement and the analysis system of a kind of eye temperature, comprising:
One eyes temperature measuring equipment, is placed in eyeball surface, including:
One temperature sensing component, electric signal is produced according to ocular surface temperature;And
One signal transfer assembly, is wireless signal by the transform electric;And
One receiving analyzer, including:
One signal receiving unit, receives the wireless signal;And
One analytic unit, according to the wireless signal analysis and judges whether the eyes are normal, it is characterised in that
The analytic unit is difference or in continuous multiple according to a temperature value of the ocular surface, between the temperature value at two time points
The change of the average value of the temperature value at time point or temperature value in continuous multiple time points is to judge whether eyes have lesion
Occur.
2. measurement and the analysis system of eye temperature as claimed in claim 1, it is characterised in that the eye temperature measurement apparatus
An antenna is additionally comprised, the antenna transmits the wireless signal to outside.
3. measurement and the analysis system of eye temperature as claimed in claim 2, it is characterised in that the antenna passes through outside electricity
Magnetic wave formation inductive and produce electric power, for should temperature sensing component and the signal transfer assembly.
4. measurement and the analysis system of eye temperature as claimed in claim 2, it is characterised in that it additionally comprises an outside day
Line, the exterior antenna can turn to pass the wireless signal.
5. measurement and the analysis system of eye temperature as claimed in claim 1, it is characterised in that the wireless signal is to meet to penetrate
Frequently, the signal of bluetooth or WiFi defineds.
6. measurement and the analysis system of eye temperature as claimed in claim 1, it is characterised in that when the surface temperature of the eyes
Nocturnal temperature and the difference of daytime temperature be less than a lower limit, then judge generation of the eyes without near-sighted or pseudo-myopia.
7. measurement and the analysis system of eye temperature as claimed in claim 6, it is characterised in that the surface temperature of the eyes
It is near-sighted or false that the difference of nocturnal temperature and daytime temperature judges that eyes may have between the lower limit and a higher limit, then
The generation of myopia.
8. measurement and the analysis system of eye temperature as claimed in claim 7, it is characterised in that the surface temperature of the eyes
The difference of nocturnal temperature and daytime temperature is more than the higher limit, then judges that eyes have the generation of myopia or pseudo-myopia.
9. measurement and the analysis system of eye temperature as claimed in claim 1, it is characterised in that when two time points of the eyes
Between the temperature value difference that measures be less than a lower limit, then judge that eyes should have the generation of xerophthalmia.
10. measurement and the analysis system of eye temperature as claimed in claim 9, it is characterised in that two point in time measurement
Temperature value is measured again between the 6th to 10 second after blink opening eyelid measures ocular surface temperature and this time measurement immediately
Ocular surface temperature, and the eyelid is persistently to open between this is measured twice.
11. measurement and the analysis system of eye temperature as claimed in claim 10, it is characterised in that when twice of the eyes
When the temperature value difference measured between point is between 0.2 DEG C to 0.4 DEG C, then judge that eyes there may be the generation of xerophthalmia.
12. measurement and the analysis system of eye temperature as claimed in claim 11, it is characterised in that when twice of the eyes
When the temperature value difference measured between point is more than 0.4 DEG C, then judge that the probability of eyes generation xerophthalmia is low.
13. measurement and the analysis system of eye temperature as claimed in claim 1, it is characterised in that the receiving analyzer is
One has installed computer, an intelligent mobile phone or the smart watch of specific software or application program.
14. measurement and the analysis system of eye temperature as claimed in claim 1, it is characterised in that the signal receiving unit bag
Include:
One portable askes answers unit there is provided the electric power needed for the signal transfer assembly and the temperature sensing component, and receives the nothing
Line signal is to produce radiofrequency signal;And
One data receipt unit, receives the radiofrequency signal to be converted to the data with ocular surface temperature.
15. measurement and the analysis system of eye temperature as claimed in claim 14, it is characterised in that the analytic unit is a meter
Calculation machine.
16. measurement and the analysis system of eye temperature as claimed in claim 1, it is characterised in that the temperature sensing component is
Multiple ring-type circuits, special applications IC or electric component of microcomputer on the surface of the eye temperature measurement apparatus.
17. measurement and the analysis system of eye temperature as claimed in claim 1, it is characterised in that eye temperature measurement dress
It is a contact lenses with temperature measurement function to put.
18. measurement and the analysis system of eye temperature as claimed in claim 1, it is characterised in that eye temperature measurement dress
Put and be placed in measure the temperature of eyes on the inside of eyeball surface and eyelid, and its size does not cover pupil.
19. a kind of receiving analyzer of eye temperature, comprising:
One signal receiving unit, receives a wireless signal, the wherein wireless signal is to include the data of ocular surface temperature;And
One analytic unit, according to the wireless signal analysis and judges whether the eyes are normal, it is characterised in that
The analytic unit is difference or in continuous multiple times according to the temperature value of ocular surface, between the temperature value at two time points
The change of the average value of the temperature value of point or temperature value in continuous multiple time points is to judge whether eyes have the generation of lesion.
20. the receiving analyzer of eye temperature as claimed in claim 19, it is characterised in that when the surface temperature of the eyes
Nocturnal temperature and the difference of daytime temperature be less than a lower limit, then judge generation of the eyes without near-sighted or pseudo-myopia.
21. the receiving analyzer of eye temperature as claimed in claim 20, it is characterised in that the surface temperature of the eyes
It is near-sighted or false that the difference of nocturnal temperature and daytime temperature judges that eyes may have between the lower limit and a higher limit, then
The generation of myopia.
22. the receiving analyzer of eye temperature as claimed in claim 21, it is characterised in that the surface temperature of the eyes
The difference of nocturnal temperature and daytime temperature is more than the higher limit, then judges that eyes have the generation of myopia or pseudo-myopia.
23. the receiving analyzer of eye temperature as claimed in claim 19, it is characterised in that when two time points of the eyes
Between the temperature value difference that measures be less than a lower limit, then judge that eyes should have the generation of xerophthalmia.
24. the receiving analyzer of eye temperature as claimed in claim 23, it is characterised in that the temperature of two point in time measurement
Angle value is to measure eye again between the 6th to 10 second that blink opening eyelid is measured after ocular surface temperature and this time measurement immediately
Eyeball surface temperature, and the eyelid is persistently to open between this is measured twice.
25. the receiving analyzer of eye temperature as claimed in claim 24, it is characterised in that when two time points of the eyes
Between the temperature value difference that measures between 0.2 DEG C to 0.4 DEG C when, then judge that eyes may have the generation of xerophthalmia.
26. the receiving analyzer of eye temperature as claimed in claim 25, it is characterised in that when two time points of the eyes
Between the temperature value difference that measures when being more than 0.4 DEG C, then judge that the probability of eyes generation xerophthalmia is low.
27. the receiving analyzer of eye temperature as claimed in claim 19, it is characterised in that the signal receiving unit bag
Include:
One portable askes answers unit, receives the wireless signal to produce radiofrequency signal;And
One data receipt unit, receives the radiofrequency signal to be converted to the data with ocular surface temperature.
28. the receiving analyzer of eye temperature as claimed in claim 27, it is characterised in that the analytic unit is a calculating
Machine.
29. the receiving analyzer of eye temperature as claimed in claim 19, it is characterised in that the receiving analyzer is one
Computer, an intelligent mobile phone or the smart watch of specific software or application program have been installed.
Applications Claiming Priority (4)
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TW102139460 | 2013-10-31 | ||
TW102139460 | 2013-10-31 | ||
TW103131266A TWI562755B (en) | 2013-10-31 | 2014-09-11 | System for measuring and analyzing ocular temperature, receiving analyzer and methods for using the same |
TW103131266 | 2014-09-11 |
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CN104586349A CN104586349A (en) | 2015-05-06 |
CN104586349B true CN104586349B (en) | 2017-07-28 |
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CN (1) | CN104586349B (en) |
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WO2018040078A1 (en) * | 2016-09-05 | 2018-03-08 | 清弘生医股份有限公司 | Wearable eye temperature monitoring device and system thereof |
JP7180216B2 (en) * | 2018-09-05 | 2022-11-30 | 日本電信電話株式会社 | Biological information analysis device, biological information analysis method, and biological information analysis system |
JP7180259B2 (en) | 2018-10-04 | 2022-11-30 | 日本電信電話株式会社 | Biological information analysis device, biological information analysis method, and biological information analysis system |
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GB8909491D0 (en) * | 1989-04-26 | 1989-06-14 | Glynn Christopher J | Device for real-time monitoring of human or animal bodily functions |
JPH09182723A (en) * | 1995-12-28 | 1997-07-15 | Taisho Pharmaceut Co Ltd | Diagnostic method for dry eye |
US6544193B2 (en) * | 1996-09-04 | 2003-04-08 | Marcio Marc Abreu | Noninvasive measurement of chemical substances |
JP3806908B2 (en) * | 2004-01-06 | 2006-08-09 | 独立行政法人産業医学総合研究所 | Tear evaporation meter |
US7410259B2 (en) * | 2006-04-27 | 2008-08-12 | International Business Machines Corporation | Optimal dynamic techniques for custom-fit eye optics |
US20080174733A1 (en) * | 2007-01-18 | 2008-07-24 | United Integrated Services Co., Ltd. | Method of using infrared thermal imager to diagnose eye diseases and the device thereof |
AU2007360363B2 (en) * | 2007-10-19 | 2013-12-05 | Sensimed Ag | Intraocular pressure monitoring device |
CN104586348A (en) * | 2013-10-31 | 2015-05-06 | 赖弘基 | Eye temperature measuring and analyzing system, receiving and analyzing device and method thereof |
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2014
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