CN104547138A - Traditional Chinese medicine composition for treating rheumatism - Google Patents
Traditional Chinese medicine composition for treating rheumatism Download PDFInfo
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- CN104547138A CN104547138A CN201510053948.8A CN201510053948A CN104547138A CN 104547138 A CN104547138 A CN 104547138A CN 201510053948 A CN201510053948 A CN 201510053948A CN 104547138 A CN104547138 A CN 104547138A
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Abstract
The invention relates to a traditional Chinese medicine composition for treating rheumatism. The traditional Chinese medicine composition comprises the following substances in parts by weight: 10-15 parts of astragalus, 10-15 parts of angelica sinensis, 10-15 parts of notopterygium roots, 10-15 parts of radix angelicae pubescentis, 10-15 parts of olibanum, 10-15 parts of myrrh, 5-15 parts of ardisia crenata, 5-15 parts of illicium henryi, 10-15 parts of cortex acanthopanacis, 10-20 parts of Chinese starjasmine stems, 10-15 parts of sargentgloryvine stems, 15-20 parts of rosa laevigata roots, 15-20 parts of heterophyllous wing seedtreeroots, 15-20 parts of rosa bracteata roots, 10-20 parts of polygonum cuspidatum, 15-20 parts of Indian damnacanthus herb roots, 15-20 parts of trumpet creeper roots, 10-15 parts of glaucousback threewingnut root-barks, 10-20 parts of hawthorn roots, 10-15 parts of humifuse euphorbia herbs, 5-15 parts of pine nodular branches, 10-15 parts of eucommia ulmoides, 10-20 parts of aralia echinocaulis roots, 10-15 parts of euonymus alatus, 10-15 parts of cassia twigs and 10-15 parts of schefflera arboricola hayata. The traditional Chinese medicine composition disclosed by the invention is capable of interacting and taking a synergistic effect, remarkable in curative effect and very worthy of being widely popularized.
Description
Technical field
The present invention relates to field of medicaments, relate in particular to one and treat rheumatismal Chinese medicine composition.
Background technology
Rheumatoid arthritis (RA) is a kind of autoimmune disease of recurrent exerbation, and main pathological manifestations is the extensive inflammation of the whole body connective tissues such as synovium of joint, eye, blood vessel, skin, serous coat, wherein outstanding with articular synovitis.Joint synovitis disease repeatedly, invades and bites bony structures and cartilaginous tissue, finally causes the destruction of articulation structure, even joint deformity, loses normal function.The misery that this disease is brought to patient is very big, and patient endangers by it deeply, and quality of the life is had a strong impact on.
Rheumatoid arthritis belongs to " arthromyodynia " category in Chinese medicine, wait exopathogen because human feeling's wind and cold is damp and hot, in attacking, impatency meridians, body QI-blood circulation is obstructed, thus causes muscle, muscles and bones, joint that swelling and pain occurs, numbness weighs, joint stuffiness, even causes the disease that joint severe deformities etc. is main manifestations.
Summary of the invention
The object of this invention is to provide one and treat rheumatismal Chinese medicine composition.
In order to realize object of the present invention, the invention provides one and treat rheumatismal Chinese medicine composition, it comprises the material of following weight portion: Radix Astragali 10-15 part, Radix Angelicae Sinensis 10-15 part, Rhizoma Et Radix Notopterygii 10-15 part, Radix Angelicae Pubescentis 10-15 part, Olibanum 10-15 part, Myrrha 10-15 part, Radix Ardisiae Crenatae 5-15 part, Radix Illicii Lanceolati 5-15 part, Cortex Acanthopancis 10-15 part, Caulis Trachelospermi 10-20 part, Caulis Sargentodoxae 10-15 part, Radix Fructus Rosae Laevigatae 15-20 part, Radix Pterospermi Heterophylli 15-20 part, Radix Rosae Bracteatae 15-20 part, Rhizoma Polygoni Cuspidati 10-20 part, Radix Damnacanthi 15-20 part, Radix Campsis 15-20 part, Cortex tripterygii hypoglauci radicis 10-15 part, Radix Crataegi 10-20 part, Herba Euphorbiae Humifusae 10-15 part, Pine Nodular Branch 5-15 part, Cortex Eucommiae 10-15 part, Cortex Araliae Echinocaulis Radicis root 10-20 part, Ramulus Euonymi 10-15 part, Ramulus Cinnamomi 10-15 part and Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 10-15 part.
Preferably, the rheumatismal Chinese medicine composition of described treatment comprises the material of following weight portion: the Radix Astragali 12 parts, Radix Angelicae Sinensis 13 parts, Rhizoma Et Radix Notopterygii 12 parts, Radix Angelicae Pubescentis 12 parts, Olibanum 12 parts, Myrrha 12 parts, Radix Ardisiae Crenatae 10 parts, Radix Illicii Lanceolati 10 parts, Cortex Acanthopancis 13 parts, Caulis Trachelospermi 15 parts, Caulis Sargentodoxae 12 parts, Radix Fructus Rosae Laevigatae 18 parts, Radix Pterospermi Heterophylli 18 parts, Radix Rosae Bracteatae 17 parts, Rhizoma Polygoni Cuspidati 18 parts, Radix Damnacanthi 16 parts, Radix Campsis 16 parts, Cortex tripterygii hypoglauci radicis 12 parts, Radix Crataegi 15 parts, Herba Euphorbiae Humifusae 12 parts, Pine Nodular Branch 10 parts, the Cortex Eucommiae 12 parts, Cortex Araliae Echinocaulis Radicis root 15 parts, Ramulus Euonymi 12 parts, Ramulus Cinnamomi 13 parts and Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 12 parts.
Preferably, the rheumatismal Chinese medicine composition of described treatment also comprises the material of following weight portion: Herba Erigerontis Annui 12 parts, Flos Caryophylli 15 parts, Radix Cacaliae Ainsliaeflorae 10 parts, Fructus Dracontomeli Duperreani 8 parts, Herba Violae Hortensis 6 parts, 20 parts, Fructus Jujubae, Zostera marina 12 parts, Herba Eupatorii 15 parts, Fructus Schisandrae Chinensis 20 parts, Rhizoma Homalomenae 12 parts, 8 parts, Herba Gnaphalii Hypoleuci and Flos Hibisci 10 parts.
Preferably, described Chinese medicine composition can be tablet, dispersible tablet, capsule, pill or ointment.
The present invention also provides the purposes of compositions in the rheumatismal Chinese medicine of preparation treatment, described compositions comprises the material of following weight portion: Radix Astragali 10-15 part, Radix Angelicae Sinensis 10-15 part, Rhizoma Et Radix Notopterygii 10-15 part, Radix Angelicae Pubescentis 10-15 part, Olibanum 10-15 part, Myrrha 10-15 part, Radix Ardisiae Crenatae 5-15 part, Radix Illicii Lanceolati 5-15 part, Cortex Acanthopancis 10-15 part, Caulis Trachelospermi 10-20 part, Caulis Sargentodoxae 10-15 part, Radix Fructus Rosae Laevigatae 15-20 part, Radix Pterospermi Heterophylli 15-20 part, Radix Rosae Bracteatae 15-20 part, Rhizoma Polygoni Cuspidati 10-20 part, Radix Damnacanthi 15-20 part, Radix Campsis 15-20 part, Cortex tripterygii hypoglauci radicis 10-15 part, Radix Crataegi 10-20 part, Herba Euphorbiae Humifusae 10-15 part, Pine Nodular Branch 5-15 part, Cortex Eucommiae 10-15 part, Cortex Araliae Echinocaulis Radicis root 10-20 part, Ramulus Euonymi 10-15 part, Ramulus Cinnamomi 10-15 part and Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 10-15 part.
Preferably, described compositions comprises the material of following weight portion: the Radix Astragali 12 parts, Radix Angelicae Sinensis 13 parts, Rhizoma Et Radix Notopterygii 12 parts, Radix Angelicae Pubescentis 12 parts, Olibanum 12 parts, Myrrha 12 parts, Radix Ardisiae Crenatae 10 parts, Radix Illicii Lanceolati 10 parts, Cortex Acanthopancis 13 parts, Caulis Trachelospermi 15 parts, Caulis Sargentodoxae 12 parts, Radix Fructus Rosae Laevigatae 18 parts, Radix Pterospermi Heterophylli 18 parts, Radix Rosae Bracteatae 17 parts, Rhizoma Polygoni Cuspidati 18 parts, Radix Damnacanthi 16 parts, Radix Campsis 16 parts, Cortex tripterygii hypoglauci radicis 12 parts, Radix Crataegi 15 parts, Herba Euphorbiae Humifusae 12 parts, Pine Nodular Branch 10 parts, the Cortex Eucommiae 12 parts of, Cortex Araliae Echinocaulis Radicis roots 15 parts, Ramulus Euonymi 12 parts, Ramulus Cinnamomi 13 parts and Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 12 parts.
Preferably, described compositions also comprises the material of following weight portion: Herba Erigerontis Annui 12 parts, Flos Caryophylli 15 parts, Radix Cacaliae Ainsliaeflorae 10 parts, Fructus Dracontomeli Duperreani 8 parts, Herba Violae Hortensis 6 parts, 20 parts, Fructus Jujubae, Zostera marina 12 parts, Herba Eupatorii 15 parts, Fructus Schisandrae Chinensis 20 parts, Rhizoma Homalomenae 12 parts, 8 parts, Herba Gnaphalii Hypoleuci and Flos Hibisci 10 parts.
Preferably, described Chinese medicine can be tablet, dispersible tablet, capsule, pill or ointment.
Chinese medicine composition of the present invention interacts, and synergism is evident in efficacy, highly widelys popularize.
Detailed description of the invention
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are for illustration of the present invention instead of limitation of the present invention.Essence according to the present invention all belongs to the scope of protection of present invention to the simple modifications that the present invention carries out.Unless otherwise stated, the percent in the present invention is percetage by weight.
Embodiment 1 ointment of the present invention
Take the Radix Astragali 12 grams, Radix Angelicae Sinensis 13 grams, Rhizoma Et Radix Notopterygii 12 grams, Radix Angelicae Pubescentis 12 grams, Olibanum 12 grams, Myrrha 12 grams, Radix Ardisiae Crenatae 10 grams, Radix Illicii Lanceolati 10 grams, Cortex Acanthopancis 13 grams, Caulis Trachelospermi 15 grams, Caulis Sargentodoxae 12 grams, Radix Fructus Rosae Laevigatae 18 grams, Radix Pterospermi Heterophylli 18 grams, Radix Rosae Bracteatae 17 grams, Rhizoma Polygoni Cuspidati 18 grams, Radix Damnacanthi 16 grams, Radix Campsis 16 grams, Cortex tripterygii hypoglauci radicis 12 grams, Radix Crataegi 15 grams, Herba Euphorbiae Humifusae 12 grams, Pine Nodular Branch 10 grams, the Cortex Eucommiae 12 grams, Cortex Araliae Echinocaulis Radicis root 15 grams, Ramulus Euonymi 12 grams, Ramulus Cinnamomi 13 grams and Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 12 grams, pulverize, cross 100 mesh sieves, add lanoline 300 grams, stir, obtain.
Embodiment 2 ointment of the present invention
Take the Radix Astragali 12 grams, Radix Angelicae Sinensis 13 grams, Rhizoma Et Radix Notopterygii 12 grams, Radix Angelicae Pubescentis 12 grams, Olibanum 12 grams, Myrrha 12 grams, Radix Ardisiae Crenatae 10 grams, Radix Illicii Lanceolati 10 grams, Cortex Acanthopancis 13 grams, Caulis Trachelospermi 15 grams, Caulis Sargentodoxae 12 grams, Radix Fructus Rosae Laevigatae 18 grams, Radix Pterospermi Heterophylli 18 grams, Radix Rosae Bracteatae 17 grams, Rhizoma Polygoni Cuspidati 18 grams, Radix Damnacanthi 16 grams, Radix Campsis 16 grams, Cortex tripterygii hypoglauci radicis 12 grams, Radix Crataegi 15 grams, Herba Euphorbiae Humifusae 12 grams, Pine Nodular Branch 10 grams, the Cortex Eucommiae 12 grams, Cortex Araliae Echinocaulis Radicis root 15 grams, Ramulus Euonymi 12 grams, Ramulus Cinnamomi 13 grams, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 12 grams, Herba Erigerontis Annui 12 grams, Flos Caryophylli 15 grams, Radix Cacaliae Ainsliaeflorae 10 grams, Fructus Dracontomeli Duperreani 8 grams, Herba Violae Hortensis 6 grams, 20 grams, Fructus Jujubae, Zostera marina 12 grams, Herba Eupatorii 15 grams, Fructus Schisandrae Chinensis 20 grams, Rhizoma Homalomenae 12 grams, 8 grams, Herba Gnaphalii Hypoleuci and Flos Hibisci 10 grams, pulverize, cross 100 mesh sieves, add lanoline 300 grams, stir, obtain.
Experimental example
Inclusive criteria:
1. rheumatoid arthritis feelings active stage is in before treatment.The diagnostic criteria of the diagnosis reference 1985 " the academic forum of therapy of combining Chinese and Western medicine wind and cold damp disease " of active stage, i.e. arthralgia number >=3, morning stiff time >=1h/d, erythrocyte sedimentation rate >=30mm/h, c reactive protein (+), rheumatoid factor (+), rheumatoid subcutaneous nodule, to possess in above 63, have that joint is red, swollen, hot simultaneously, 3 persons can be diagnosed as rheumatoid arthritis active stage in pain.
2. the voluntary patient also accepting to pay a return visit as study subject.
Exclusion standard:
1. advanced joint generation severe deformities, joints lose merit able one;
2. basic body constitution is poor, is associated with the obvious abnormal person of cardiovascular system diseases, disease of hematopoietic system or hepatic and renal function;
3. gestation and women breast-feeding their children;
4. the patient of peptic ulcer patients of active is in;
5. the person that suffers from mental sickness;
6. the age is less than 18 years old or is greater than 65 years old.
Meet above-mentioned standard 50 routine patients are divided into two groups, wherein treatment group 1 be 25 example, man 12 example, female 13 example, age 23-61 year, 41.5 years old mean age; Treatment group 2 be 25 example, man 12 example, female 13 example, age 22-62 year, 41.6 years old mean age.The sex of two groups of patients, age, the course of disease, and the basic document there was no significant difference (P > 0.05) such as arthroncus number, articular pain number, morning stiff time, grip size, patient's evaluation, doctor evaluation, DAS28 scoring before treatment, there is comparability.
Treatment group 1 uses the ointment of preparation in embodiment 1 to treat, every day twice, and each use 20 grams of ointment uniform application, at arthritis sore spot, are treated 7 weeks continuously.
Treatment group 2 uses the ointment of preparation in embodiment 2 to treat, every day twice, and each use 20 grams of ointment uniform application, at arthritis sore spot, are treated 7 weeks continuously.
Criterion of therapeutical effect
Curative effect determinate standard with reference to rheumatism Professional Committee of CAIM (Chinese Association Of Integrative Medicine) revision in 1988 is according to specifying.Cure; Arthralgia disappears, and function is improved or recovered normal, and main test index recovers normal; Effective; Arthralgia is clearly better or disappears, and function is improved, main test index recovery or close normal; Effective: arthralgia takes a turn for the better, main test index trend is normal; Invalid: clinical symptoms and sign are without improvement, and main test index is without improvement.
Statistical method
Utilize SPSS 13.0 software to process and analyze to experimental data, measurement data is with mean ± standard deviation
represent, adopt t inspection, enumeration data adopts x
2inspection, P < 0.05 represents that difference has statistical significance.
Result
Through treatment, for treatment group 1, cure 10 examples, effective 6 examples, effective 5 examples, invalid 4 examples, total effective rate is 84%, for treatment group 2, cures 12 examples, effective 7 examples, effective 5 examples, and invalid 1 example, total effective rate is 96%.Two groups of total effective rate comparing differences have statistical significance (P < 0.05).
Untoward reaction and toxic and side effects supervision
By detect patient blood pressure, pulse, whether there is Nausea and vomiting, dizzy clinical symptoms judges untoward reaction.Find that the systolic pressure of all patients is between 90-140mmHg, diastolic pressure is between 60-90mmHg, and pulse is 60-100 beat/min, and blood pressure and pulse all within normal range, and does not occur Nausea and vomiting, dizzy clinical symptoms.This illustrates that pharmaceutical composition of the present invention does not have obvious untoward reaction, and then proves that medicine does not have obvious toxic and side effects for human body.
Claims (8)
1. the rheumatismal Chinese medicine composition for the treatment of, it is characterized in that, it comprises the material of following weight portion: Radix Astragali 10-15 part, Radix Angelicae Sinensis 10-15 part, Rhizoma Et Radix Notopterygii 10-15 part, Radix Angelicae Pubescentis 10-15 part, Olibanum 10-15 part, Myrrha 10-15 part, Radix Ardisiae Crenatae 5-15 part, Radix Illicii Lanceolati 5-15 part, Cortex Acanthopancis 10-15 part, Caulis Trachelospermi 10-20 part, Caulis Sargentodoxae 10-15 part, Radix Fructus Rosae Laevigatae 15-20 part, Radix Pterospermi Heterophylli 15-20 part, Radix Rosae Bracteatae 15-20 part, Rhizoma Polygoni Cuspidati 10-20 part, Radix Damnacanthi 15-20 part, Radix Campsis 15-20 part, Cortex tripterygii hypoglauci radicis 10-15 part, Radix Crataegi 10-20 part, Herba Euphorbiae Humifusae 10-15 part, Pine Nodular Branch 5-15 part, Cortex Eucommiae 10-15 part, red principal columns of a hall wood root 10-20 part, Ramulus Euonymi 10-15 part, Ramulus Cinnamomi 10-15 part and Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 10-15 part.
2. the rheumatismal Chinese medicine composition for the treatment of according to claim 1, it is characterized in that, it comprises the material of following weight portion: the Radix Astragali 12 parts, Radix Angelicae Sinensis 13 parts, Rhizoma Et Radix Notopterygii 12 parts, Radix Angelicae Pubescentis 12 parts, Olibanum 12 parts, Myrrha 12 parts, Radix Ardisiae Crenatae 10 parts, Radix Illicii Lanceolati 10 parts, Cortex Acanthopancis 13 parts, Caulis Trachelospermi 15 parts, Caulis Sargentodoxae 12 parts, Radix Fructus Rosae Laevigatae 18 parts, Radix Pterospermi Heterophylli 18 parts, Radix Rosae Bracteatae 17 parts, Rhizoma Polygoni Cuspidati 18 parts, Radix Damnacanthi 16 parts, Radix Campsis 16 parts, Cortex tripterygii hypoglauci radicis 12 parts, Radix Crataegi 15 parts, Herba Euphorbiae Humifusae 12 parts, Pine Nodular Branch 10 parts, the Cortex Eucommiae 12 parts, red principal columns of a hall wood root 15 parts, Ramulus Euonymi 12 parts, Ramulus Cinnamomi 13 parts and Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 12 parts.
3. the rheumatismal Chinese medicine composition for the treatment of according to claim 1 and 2, it is characterized in that, it also comprises the material of following weight portion: Herba Erigerontis Annui 12 parts, Flos Caryophylli 15 parts, Radix Cacaliae Ainsliaeflorae 10 parts, Fructus Dracontomeli Duperreani 8 parts, Herba Violae Hortensis 6 parts, 20 parts, Fructus Jujubae, Zostera marina 12 parts, Herba Eupatorii 15 parts, Fructus Schisandrae Chinensis 20 parts, Rhizoma Homalomenae 12 parts, 8 parts, Herba Gnaphalii Hypoleuci and Flos Hibisci 10 parts.
4. the rheumatismal Chinese medicine composition for the treatment of according to claim 3, is characterized in that, described Chinese medicine composition can be tablet, dispersible tablet, capsule, pill or ointment.
5. the purposes of compositions in the rheumatismal Chinese medicine of preparation treatment, it is characterized in that, described compositions comprises the material of following weight portion: Radix Astragali 10-15 part, Radix Angelicae Sinensis 10-15 part, Rhizoma Et Radix Notopterygii 10-15 part, Radix Angelicae Pubescentis 10-15 part, Olibanum 10-15 part, Myrrha 10-15 part, Radix Ardisiae Crenatae 5-15 part, Radix Illicii Lanceolati 5-15 part, Cortex Acanthopancis 10-15 part, Caulis Trachelospermi 10-20 part, Caulis Sargentodoxae 10-15 part, Radix Fructus Rosae Laevigatae 15-20 part, Radix Pterospermi Heterophylli 15-20 part, Radix Rosae Bracteatae 15-20 part, Rhizoma Polygoni Cuspidati 10-20 part, Radix Damnacanthi 15-20 part, Radix Campsis 15-20 part, Cortex tripterygii hypoglauci radicis 10-15 part, Radix Crataegi 10-20 part, Herba Euphorbiae Humifusae 10-15 part, Pine Nodular Branch 5-15 part, Cortex Eucommiae 10-15 part, red principal columns of a hall wood root 10-20 part, Ramulus Euonymi 10-15 part, Ramulus Cinnamomi 10-15 part and Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 10-15 part.
6. purposes according to claim 5, it is characterized in that, described compositions comprises the material of following weight portion: the Radix Astragali 12 parts, Radix Angelicae Sinensis 13 parts, Rhizoma Et Radix Notopterygii 12 parts, Radix Angelicae Pubescentis 12 parts, Olibanum 12 parts, Myrrha 12 parts, Radix Ardisiae Crenatae 10 parts, Radix Illicii Lanceolati 10 parts, Cortex Acanthopancis 13 parts, Caulis Trachelospermi 15 parts, Caulis Sargentodoxae 12 parts, Radix Fructus Rosae Laevigatae 18 parts, Radix Pterospermi Heterophylli 18 parts, Radix Rosae Bracteatae 17 parts, Rhizoma Polygoni Cuspidati 18 parts, Radix Damnacanthi 16 parts, Radix Campsis 16 parts, Cortex tripterygii hypoglauci radicis 12 parts, Radix Crataegi 15 parts, Herba Euphorbiae Humifusae 12 parts, Pine Nodular Branch 10 parts, the Cortex Eucommiae 12 parts, red principal columns of a hall wood root 15 parts, Ramulus Euonymi 12 parts, Ramulus Cinnamomi 13 parts and Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 12 parts.
7. the purposes according to claim 5 or 6, it is characterized in that, described compositions also comprises the material of following weight portion: Herba Erigerontis Annui 12 parts, Flos Caryophylli 15 parts, Radix Cacaliae Ainsliaeflorae 10 parts, Fructus Dracontomeli Duperreani 8 parts, Herba Violae Hortensis 6 parts, 20 parts, Fructus Jujubae, Zostera marina 12 parts, Herba Eupatorii 15 parts, Fructus Schisandrae Chinensis 20 parts, Rhizoma Homalomenae 12 parts, 8 parts, Herba Gnaphalii Hypoleuci and Flos Hibisci 10 parts.
8. purposes according to claim 7, is characterized in that, described Chinese medicine can be tablet, dispersible tablet, capsule, pill or ointment.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106943469A (en) * | 2017-03-09 | 2017-07-14 | 杨根生 | A kind of Chinese medicine composition for treating rheumatism |
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| CN103893639A (en) * | 2014-04-15 | 2014-07-02 | 韩世昌 | Traditional Chinese medicine composition for treating rheumatoid arthritis and preparation method thereof |
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| CN103893639A (en) * | 2014-04-15 | 2014-07-02 | 韩世昌 | Traditional Chinese medicine composition for treating rheumatoid arthritis and preparation method thereof |
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| CN106943469A (en) * | 2017-03-09 | 2017-07-14 | 杨根生 | A kind of Chinese medicine composition for treating rheumatism |
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Application publication date: 20150429 |