CN104547081B - A kind of medicine being used for the treatment of chronic renal insufficiency chronic kidney hypofunction disease - Google Patents
A kind of medicine being used for the treatment of chronic renal insufficiency chronic kidney hypofunction disease Download PDFInfo
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Abstract
Be used for the treatment of a medicine for chronic renal insufficiency chronic kidney hypofunction disease, comprise with the following raw material of weight portion note: Cornu Cervi Pantotrichum 70 ~ 90, Radix Aconiti Lateralis Preparata 17 ~ 23, Ramulus Cinnamomi 70 ~ 90, Herba Cistanches 170 ~ 230.Preferably, also comprise with the following raw material of weight portion note: Fructus Corni 170 ~ 230, Radix Rehmanniae Preparata 85 ~ 115, the Rhizoma Atractylodis Macrocephalae 170 ~ 230, Radix Angelicae Sinensis 170 ~ 230, the Radix Astragali 45 ~ 55.Preferably, also comprise with the following raw material of weight portion note: Poria 170 ~ 230, Semen Plantaginis 170 ~ 230, Cortex Moutan 17 ~ 23.Preferably, also comprise with the following raw material of weight portion note: Radix Achyranthis Bidentatae 85 ~ 115, Radix Et Rhizoma Rhei 45 ~ 55.The present invention can the kidney invigorating gas, invigorating kidney-YANG, rehabilitation renal function, can be used in the chronic renal insufficiency caused by insufficiency of kidney-YANG, chronic kidney hypofunction, limbs are weak, waist knee joint cold extremities, dysuria, frequent micturition or polyuria at night, complexion is dim or dark, expression is dull, two lower limb depression edema, face eye edema, blood urea nitrogen raises, creatinine raises, the chronic renal insufficiency that hypertensive nephropathy, diabetic nephropathy and drug induced injury or other reasons cause, the treatment of chronic kidney hypofunction disease.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly a kind of medicine being used for the treatment of chronic renal insufficiency chronic kidney hypofunction disease.
Background technology
Renal insufficiency (renalinsufficiency) is caused by many reasons, and its symptom is glomerule heavy damage, makes health at excretion metabolism refuse and regulates the Comprehensive Clinical disease group got muddled in Water-Electrolyte, acid-base balance etc.Be divided into acute renal insufficiency and chronic renal insufficiency.Prognosis is seriously bad, is one of principal disease threatening human life.
Wherein, chronic renal insufficiency is the final result of various progressive renal disease.In doctor trained in Western medicine, analyze its cause of disease is:
1, chronic glomerulonephritis.As IGA nephropathy, membranoprolifer ative glomerulonephritis; Focal segmental sclerosing glomerulonephritis and Pathology of Mesangial Proliferative Glomerulonephritis etc.
2, the kidney damage caused by Developmental and Metabolic Disorder, as diabetic nephropathy, gouty nephropathy and features of amyloid nephropathy etc.;
3, vascular nephropathy becomes, as hypertension, renal vascular hypertension, ANS etc.;
4, heritability nephropathy, as polycystic kidney, Alport syndrome etc.;
5, infectious nephropathy, as chronic pyelonephritis, renal tuberculosis etc.;
6, whole body system disease, as lupus nephritis, vasculitis kidney damage, multiple myeloma etc.;
7, toxic nephrosis, as analgesics nephropathy, heavy metal nephropathy etc.;
8, obstructive nephropathy, as ureteral obstruction; Reflux nephropathy, lithangiuria etc.
In existing each theory of Chinese medical science, the thinking for the treatment of renal insufficiency, the conventional blood circulation promoting and blood stasis dispelling of chronic kidney hypofunction disease, dampness removing the turbid descending, mainly contain Radix Salviae Miltiorrhizae, Radix Achyranthis Bidentatae, Herba Leonuri, Herba Pogostemonis, Herba Eupatorii, the Rhizoma Pinelliae, Fructus Liquidambaris, Semen Plantaginis, Talcum, Radix Et Rhizoma Rhei, Radix Glycyrrhizae in the prescription established, lumbago severe one adds the Cortex Eucommiae, Radix Dipsaci; Nausea and vomiting severe one adds Caulis Bambusae In Taenia, Haematitum, Flos Inulae; Constipation adds Natrii Sulfas, Semen Pharbitidis; Dysuria adds Caulis Akebiae, Cortex Phellodendri; Wet Sheng adds Rhizoma Atractylodis, Cortex Magnoliae Officinalis, Fructus Amomi; Hematuria adds Pollen Typhae, Cacumen Platycladi, Rhizoma Imperatae; Herba Lysimachiae, Spora Lygodii, Endothelium Corneum Gigeriae Galli is added with calculus person; Urine is cultivated positive and is added Herba Hedyotidis Diffusae, Herba Taraxaci, Herba Violae and Fructus Forsythiae; Tongue secretly has ecchymosis, and person can give FUFANG DANSHEN ZHUSHEYE or MAILUONING ZHUSHEYE 20ml, adds in 5% Glucose Liquid 250ml, 1 intravenous drip every day.In the therapeutic process of renal failure, really can play certain regulating functional activities of qi, the bright effect of sun of removing heat by catharsis.
Chinese patent literature, CN103550749A describes a kind of Chinese medicine for the treatment of nephropathy, described Chinese medicine comprises following component: Fructus Foeniculi 6-12g, Radix Cirsii Japonici 5-15g, Herba Lysimachiae 6-12g, Rhizoma Acori Graminei 5-15g, Cortex Mori 5-15g, Herba Hedyotidis Diffusae 6-12g, Rhizoma Drynariae 6-12g, Herba Pogostemonis 6-12g etc., medicine of the present invention has expelling wind and cold, blood circulation promoting and blood stasis dispelling, effect of hard masses softening and resolving, its consumption is little, cure rate is high, cure rate is up to 98%, the efficacy of a drug concentrates effect rapidly, have no side effect, duration of efficacy is long, cost is low, patient is subject to painful little, effectively can treat nephritis, the diseases such as nephrotic edema.It is also the scheme adopting expelling wind and cold, blood circulation promoting and blood stasis dispelling, hard masses softening and resolving.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of medicine being used for the treatment of chronic renal insufficiency chronic kidney hypofunction disease, for problems of the prior art: such as chronic renal insufficiency, the sick therapeutic effect of chronic kidney hypofunction significantly, easily not repeatedly, cause aggravation, patient mental's pressure be large, financial burden weight.The present invention can the kidney invigorating gas, invigorating kidney-YANG, rehabilitation renal function, can be used in the chronic renal insufficiency caused by insufficiency of kidney-YANG, chronic kidney hypofunction, or the chronic renal insufficiency that hypertensive nephropathy, diabetic nephropathy and drug induced injury or other reasons cause, the treatment of chronic kidney hypofunction disease.
For solving the problems of the technologies described above, the technical solution adopted in the present invention is: a kind of medicine being used for the treatment of chronic renal insufficiency chronic kidney hypofunction disease, comprises with the following raw material of weight portion note:
Cornu Cervi Pantotrichum 70 ~ 90, Radix Aconiti Lateralis Preparata 17 ~ 23, Ramulus Cinnamomi 70 ~ 90, Herba Cistanches 170 ~ 230.
Preferably, also comprise with the following raw material of weight portion note:
Fructus Corni 170 ~ 230, Radix Rehmanniae Preparata 85 ~ 115, the Rhizoma Atractylodis Macrocephalae 170 ~ 230, Radix Angelicae Sinensis 170 ~ 230, the Radix Astragali 45 ~ 55.
Preferably, also comprise with the following raw material of weight portion note:
Poria 170 ~ 230, Semen Plantaginis 170 ~ 230, Cortex Moutan 17 ~ 23.
Preferably, also add with the following raw material of weight portion note:
Radix Achyranthis Bidentatae 85 ~ 115, Radix Et Rhizoma Rhei 45 ~ 55.
Preferably, be made up of following raw material that remembering with weight portion:
Cornu Cervi Pantotrichum 70, Radix Aconiti Lateralis Preparata 17, Ramulus Cinnamomi 70, Herba Cistanches 170, Fructus Corni 170, Radix Rehmanniae Preparata 85, the Rhizoma Atractylodis Macrocephalae 170, Radix Angelicae Sinensis 170, the Radix Astragali 45, Poria 170, Semen Plantaginis 170, Cortex Moutan 17, Radix Achyranthis Bidentatae 85, Radix Et Rhizoma Rhei 45.
Preferably, be made up of following raw material that remembering with weight portion:
Cornu Cervi Pantotrichum 75, Radix Aconiti Lateralis Preparata 18, Ramulus Cinnamomi 85, Herba Cistanches 225, Fructus Corni 210, Radix Rehmanniae Preparata 105, the Rhizoma Atractylodis Macrocephalae 180, Radix Angelicae Sinensis 210, the Radix Astragali 51, Poria 185, Semen Plantaginis 205, Cortex Moutan 19, Radix Achyranthis Bidentatae 105, Radix Et Rhizoma Rhei 52.
Preferably, be made up of following raw material that remembering with weight portion:
Cornu Cervi Pantotrichum 80, Radix Aconiti Lateralis Preparata 20, Ramulus Cinnamomi 80, Herba Cistanches 200, Fructus Corni 200, Radix Rehmanniae Preparata 100, the Rhizoma Atractylodis Macrocephalae 200, Radix Angelicae Sinensis 200, the Radix Astragali 50, Poria 200, Semen Plantaginis 200, Cortex Moutan 20, Radix Achyranthis Bidentatae 100, Radix Et Rhizoma Rhei 50.
Preferably, be made up of following raw material that remembering with weight portion:
Cornu Cervi Pantotrichum 85, Radix Aconiti Lateralis Preparata 22, Ramulus Cinnamomi 88, Herba Cistanches 190, Fructus Corni 190, Radix Rehmanniae Preparata 90, the Rhizoma Atractylodis Macrocephalae 210, Radix Angelicae Sinensis 190, the Radix Astragali 48, Poria 220, Semen Plantaginis 220, Cortex Moutan 20, Radix Achyranthis Bidentatae 90, Radix Et Rhizoma Rhei 45.
Preferably, be made up of following raw material that remembering with weight portion:
Cornu Cervi Pantotrichum 90, Radix Aconiti Lateralis Preparata 23, Ramulus Cinnamomi 90, Herba Cistanches 230, Fructus Corni 230, Radix Rehmanniae Preparata 115, the Rhizoma Atractylodis Macrocephalae 230, Radix Angelicae Sinensis 230, the Radix Astragali 55, Poria 230, Semen Plantaginis 230, Cortex Moutan 23, Radix Achyranthis Bidentatae 115, Radix Et Rhizoma Rhei 55.
After above raw material is cleaned impurity, oven dry, pulverizing, mix homogenously makes ball, capsule, sheet, granule, powder.
Inventor took up a job as a doctor for more than 40 years, by more than 20 years to the clinical treatment of chronic renal insufficiency, chronic kidney hypofunction disease and research, the medicine of formula is made, dose titration, different sexes and age difference, renal function injury degree difference, comparative study repeatedly, repeatedly proved by clinical, finally determine that this formula makes scheme.
Pharmaceutical formulation mechanism of the present invention and suit the medicine to the illness:
A kind of medicine being used for the treatment of chronic renal insufficiency chronic kidney hypofunction disease provided by the invention, prescription feature and pharmacology analysis as follows:
Prescription of the present invention adopts a large amount of temperature compensation medicine and the smart medicine of YIN nourishing benefit to associate with, and it is main for being intended to kidney-replenishing, and tonifying both YIN and YANG, because the kidney being a ZANG-organ containing both water and fire.The sick feature of renal insufficiency, chronic kidney hypofunction: " sun is often not enough ", therefore thinking of the present invention is: YANG invigorating is angry, and based on YANG invigorating, help and ooze profit with logical faling apart, residence rushes down in benefit, to rush down middle supplement, makes tonify without causing stagnation.
Record in " Shan Buming hospital opinion ": fire from the gater of life is water the yang aspect of yang, the quiet and seething person of husband's water body, the merit of gas, the use of fire, and the gate of vitality has fire, then kidney Animando.All medicines share, and supporing yang is weak with activating QI, and YIN nourishing is empty makes kidney yang rouse oneself with anger, and gasification is multiple normal, then all cards are from removing.
We cure mainly insufficiency of kidney-YANG, fire from the gater of life fails, can not the replenishing vital QI with drugs of warm nature part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, yang-energy day declines, often creeping chill is had below half body, exterior and interior relation between kidney and bladder, insufficiency of kidney-YANG can not activating QI to promote diuresis, water is wet to spread unchecked, then edema, dysuria, or bladder loses in constraint, clear urine in large amounts is anti-many, YANG declining when YIN growing at nightfall, therefore nocturnal pollakiuria, insufficiency of kidney-YANG, water liquid is not changed, pale tongue and fat, deep-thready pulse or heavy weak and slow, for resembling of deficiency of kidney yang, insufficiency of kidney-YANG, warm incapability, disturbance in functioning of QI, the metabolism of water liquid is not normal is the pathogenesis of assertive evidence, control supporing YANG and nourishing YANG to be method, nourishing renal yang to restrict excessive yin, with the be shaded or hidden for foliage that disappears, be aided with activating QI to promote diuresis.
Cornu Cervi Pantotrichum, Radix Aconiti Lateralis Preparata, Ramulus Cinnamomi, Herba Cistanches in side: mend fiery invigorating yangqi, the void of kidney-replenishing, lights a fire kidney qi, helps answering of gasification, the kidney being a ZANG-organ containing both water and fire, interior house is Kidney-Yin kidney-Yang, yang-energy depletion of YIN is not then changed, " kind YANG invigorating person ", in treating YANG within YIN, Yang Zheyin must be obtained and helps, and biochemical infinite, be monarch drug.
Fructus Corni, Radix Rehmanniae Preparata, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, the Radix Astragali in side: enriching yin and nourishing kidney are promoted the production of body fluid, and tonifying liver supports spleen, steam Qinghua gas, the effect of YANG promoting growth while YIN promoting generation to receive, in side, yang-tonifying drug is many, and drugs for nourishing yin is few, YANG invigorating and biochemical, and bulging kidney qi is ministerial drug.
Poria, Semen Plantaginis in side, join Ramulus Cinnamomi temperature aqueous vapor, and Cortex Moutan is joined Ramulus Cinnamomi and adjusted blood system stagnant, and three medicines share, and residence rushes down in benefit, goes and mend capable in order to do heresy, and make all drugs for nourishing yin and may help the wet anxiety hindering heresy, is adjuvant drug.
In side, Radix Achyranthis Bidentatae, Radix Et Rhizoma Rhei, Semen Plantaginis three medicine share, and help diuresis, are excreted by kidney poison by two the moon, for making medicine.
Cornu Cervi Pantotrichum: sweet-salty, enters Liver and kidney warp.Function: kidney invigorating and YANG supporting, spermatogenesis benefit blood, salty to enter kidney, the kidney invigorating governor vessel and invigorating kidney-YANG, controlling kidney-Yang void and decline, is the product of flesh and blood, warm lower unit.Modern pharmacological research: have excited nephrocyte, rehabilitation renal function, pigment of enriching blood, controls nephropathy anemia.Join Radix Aconiti Lateralis Preparata, Radix Rehmanniae Preparata, Fructus Corni, Radix Angelicae Sinensis, Cortex Moutan, the kidney warming is enriched blood.
Radix Rehmanniae Preparata: tepor enters Liver and kidney warp.Function: benefiting kidney-essence is the key medicine of nourishing YIN void, tonifying five ZANG-organs promoting generation of vital essence and blood.Modern pharmacological research: have diuresis.Join Cornu Cervi Pantotrichum, Radix Aconiti Lateralis Preparata, Fructus Corni, Cortex Moutan, Radix Achyranthis Bidentatae, tonifying both YIN and YANG.
Cortex Moutan: be pungently slightly cold into Liver and kidney warp, promoting blood circulation to remove blood stasis, controls hematuria.Join Radix Et Rhizoma Rhei, Radix Achyranthis Bidentatae, conducting blood to flow downwards row kidney poison.
Radix Aconiti Lateralis Preparata: hot enter spleen kidney channel, poisonous.Function: logical 12 warps, mends fiery recuperating depleted YANG, and cold expelling is by wet, and capable 12 warps of bleed medicine, strengthen fire from the gater of life, supporing yang warming kidney for dispelling cold.Join Cornu Cervi Pantotrichum, Radix Rehmanniae Preparata, Fructus Corni, Radix Angelicae Sinensis, Herba Cistanches, Ramulus Cinnamomi, Radix Achyranthis Bidentatae, warming and recuperating the kidney-YANG.Join the Radix Astragali, Poria, the Rhizoma Atractylodis Macrocephalae, Semen Plantaginis, Radix Et Rhizoma Rhei, warming YANG to promote diuresis is subsided a swelling.
Fructus Corni: enter Liver and kidney warp.Function: liver and kidney tonifying.Modern pharmacological research: have remarkable diuretic antihypertensive effect.
Poria: liver is faded in spleen kidney channel.Function: ooze diuretic and wet, diuresis is harnessed the river swollen.Modern pharmacological research: have diuresis blood sugar reducing function, lasting diuresis, increases urine volume.Join the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Semen Plantaginis, diuretic be wet, consumer edema.
The Radix Astragali: sweet flavour enters the spleen warp.Function: tonifying Qi and lifting yang, inducing diuresis to remove edema, void edema.Modern pharmacological research: control nephropathy edema, albuminuria, uremia, improve renal function effect.Join Radix Angelicae Sinensis, Poria, Semen Plantaginis, Radix Achyranthis Bidentatae, the Rhizoma Atractylodis Macrocephalae, Ramulus Cinnamomi, fill blood, subside a swelling.
Radix Angelicae Sinensis: Xin Wen enters liver spleen channel.Function: enrich blood.Join the Radix Astragali, Radix Rehmanniae Preparata, increase blood nourishing function, control nephropathy anemia.
Ramulus Cinnamomi: Gan Wen enters urinary bladder channel.Function: activating YANG for promoting diuresis wets (herbal classic note), activating YANG for promoting diuresis is except stem invasion by pathogenic cold burning pain.Join the Rhizoma Atractylodis Macrocephalae, Radix Achyranthis Bidentatae, the Radix Astragali, Semen Plantaginis, Poria, activating YANG for promoting diuresis.
Herba Cistanches: salty in the mouth, enters kidney channel.Function: warming the kidney to invigorate YANG is the key medicine of kidney-replenishing, controls fire and to decline damage of essence, dribble of urine, weakness of the lower extremities.Join Radix Aconiti Lateralis Preparata, Radix Rehmanniae Preparata, Cornu Cervi Pantotrichum, Cortex Moutan, Ramulus Cinnamomi, with kidney-replenishing.
Semen Plantaginis: the sweet spleen kidney wing that fades in takes off warp.Function: diuresis, tonneau urine.Modern pharmacological research: have excretion carbamide, sodium chloride and uric acid effect.Join the Radix Astragali, Poria, the Rhizoma Atractylodis Macrocephalae, Ramulus Cinnamomi, Radix Achyranthis Bidentatae, inducing diuresis to remove edema.
The Rhizoma Atractylodis Macrocephalae: Gan Wen enters spleen channel.Function: control retention of water-damp in the body, urgent micturition, frequent micturition edema.Modern pharmacological research: have obviously lasting diuresis.Join the Radix Astragali, Radix Et Rhizoma Rhei, Semen Plantaginis, Radix Achyranthis Bidentatae, Poria, inducing diuresis to remove edema.
Radix Achyranthis Bidentatae: picric acid enters kidney channel.Function: inducing diuresis for treating stranguria syndrome, controls hematuria, liver and kidney tonifying." detailed outline " is noted.Control five types of stranguria hematuria, pains in the penis " large bright book on Chinese herbal medicine " are noted, sharp defecation.Modern pharmacological research: have antihypertensive diuretic effect.Join Radix Et Rhizoma Rhei, Semen Plantaginis, diuresis, row's kidney poison.
Radix Et Rhizoma Rhei: function removing mass clots absorbing, clearing away damp-heat.Join Cortex Moutan, Poria, Semen Plantaginis, the Rhizoma Atractylodis Macrocephalae, Radix Achyranthis Bidentatae, control hematuria, diuresis relieving constipation, kidney poison is excreted by two the moon.
The present invention can the kidney invigorating gas, invigorating kidney-YANG, rehabilitation renal function, can be used in the chronic renal insufficiency caused by insufficiency of kidney-YANG, chronic kidney hypofunction, limbs are weak, waist knee joint cold extremities, dysuria, frequent micturition or polyuria at night, complexion is dim or dark, expression is dull, two lower limb depression edema, face eye edema, blood urea nitrogen raises, creatinine raises, the chronic renal insufficiency that hypertensive nephropathy, diabetic nephropathy and drug induced injury or other reasons cause, the treatment of chronic kidney hypofunction disease.
This formula advantage is: evident in efficacy, not easily repeatedly, have no side effect, short treating period, instant effect, patient economy burden be light, without the need to hospitalization, outpatient service can be cured.For the clinical treatment of traditional Chinese medical herbal treatment chronic renal insufficiency, chronic kidney hypofunction disease and research achieve important breakthrough, solve the misery of sufferer, simultaneously also for country saves a large amount of cooperative medical service program of rural areas and social security medical benefits fund, bring good economic benefit and social benefit to country.
Detailed description of the invention
Embodiment 1:
Be used for the treatment of a medicine for chronic renal insufficiency chronic kidney hypofunction disease, comprise with the following raw material of weight portion note: Cornu Cervi Pantotrichum 70 ~ 90, Radix Aconiti Lateralis Preparata 17 ~ 23, Ramulus Cinnamomi 70 ~ 90, Herba Cistanches 170 ~ 230.
In preferred scheme, also comprise with the following raw material of weight portion note:
Fructus Corni 170 ~ 230, Radix Rehmanniae Preparata 85 ~ 115, the Rhizoma Atractylodis Macrocephalae 170 ~ 230, Radix Angelicae Sinensis 170 ~ 230, the Radix Astragali 45 ~ 55.
In preferred scheme, also comprise with the following raw material of weight portion note:
Poria 170 ~ 230, Semen Plantaginis 170 ~ 230, Cortex Moutan 17 ~ 23.
In preferred scheme, also comprise with the following raw material of weight portion note:
Radix Achyranthis Bidentatae 85 ~ 115, Radix Et Rhizoma Rhei 45 ~ 55, Semen Plantaginis 85 ~ 115.
Embodiment 2:
On the basis of embodiment 1, a kind of medicine being used for the treatment of chronic renal insufficiency chronic kidney hypofunction disease, further in preferred scheme, comprises with the following raw material of weight portion note:
Cornu Cervi Pantotrichum 70, Radix Aconiti Lateralis Preparata 17, Ramulus Cinnamomi 70, Herba Cistanches 170, Fructus Corni 170, Radix Rehmanniae Preparata 85, the Rhizoma Atractylodis Macrocephalae 170, Radix Angelicae Sinensis 170, the Radix Astragali 45, Poria 170, Semen Plantaginis 170, Cortex Moutan 17, Radix Achyranthis Bidentatae 85, Radix Et Rhizoma Rhei 45.
Embodiment 3:
On the basis of embodiment 1, a kind of medicine being used for the treatment of chronic renal insufficiency chronic kidney hypofunction disease, further in preferred scheme, comprises with the following raw material of weight portion note:
Cornu Cervi Pantotrichum 75, Radix Aconiti Lateralis Preparata 18, Ramulus Cinnamomi 85, Herba Cistanches 225, Fructus Corni 210, Radix Rehmanniae Preparata 105, the Rhizoma Atractylodis Macrocephalae 180, Radix Angelicae Sinensis 210, the Radix Astragali 51, Poria 185, Semen Plantaginis 205, Cortex Moutan 19, Radix Achyranthis Bidentatae 105, Radix Et Rhizoma Rhei 52.
Embodiment 4:
On the basis of embodiment 1, a kind of medicine being used for the treatment of chronic renal insufficiency chronic kidney hypofunction disease, further in preferred scheme, comprises with the following raw material of weight portion note:
Cornu Cervi Pantotrichum 80, Radix Aconiti Lateralis Preparata 20, Ramulus Cinnamomi 80, Herba Cistanches 200, Fructus Corni 200, Radix Rehmanniae Preparata 100, the Rhizoma Atractylodis Macrocephalae 200, Radix Angelicae Sinensis 200, the Radix Astragali 50, Poria 200, Semen Plantaginis 200, Cortex Moutan 20, Radix Achyranthis Bidentatae 100, Radix Et Rhizoma Rhei 50.
Embodiment 5:
On the basis of embodiment 1, a kind of medicine being used for the treatment of chronic renal insufficiency chronic kidney hypofunction disease, further in preferred scheme, comprises with the following raw material of weight portion note:
Cornu Cervi Pantotrichum 85, Radix Aconiti Lateralis Preparata 22, Ramulus Cinnamomi 88, Herba Cistanches 190, Fructus Corni 190, Radix Rehmanniae Preparata 90, the Rhizoma Atractylodis Macrocephalae 210, Radix Angelicae Sinensis 190, the Radix Astragali 48, Poria 220, Semen Plantaginis 220, Cortex Moutan 20, Radix Achyranthis Bidentatae 90, Radix Et Rhizoma Rhei 45.
Embodiment 6:
On the basis of embodiment 1, a kind of medicine being used for the treatment of chronic renal insufficiency chronic kidney hypofunction disease, further in preferred scheme, comprises with the following raw material of weight portion note:
Cornu Cervi Pantotrichum 90, Radix Aconiti Lateralis Preparata 23, Ramulus Cinnamomi 90, Herba Cistanches 230, Fructus Corni 230, Radix Rehmanniae Preparata 115, the Rhizoma Atractylodis Macrocephalae 230, Radix Angelicae Sinensis 230, the Radix Astragali 55, Poria 230, Semen Plantaginis 230, Cortex Moutan 23, Radix Achyranthis Bidentatae 115, Radix Et Rhizoma Rhei 55.
Embodiment 7:
After the raw material of embodiment 1 ~ 6 is cleaned impurity, oven dry, pulverizing, mix homogenously makes the Chinese patent medicine nephropathy health preparation of dispersible tablet, ball, capsule, sheet, granule, powder.
Medical record observation of curative effect:
The prescription of the traditional Chinese medical science of the present invention, inventor is called " nephropathy healthy dispersion tablet ", and clinical patient comes to clinic case, be the work for the treatment of limit, limit, mostly take check renal function in laboratory after month, visible renal function takes a turn for the better in various degree, blood urea nitrogen, creatinine declines in various degree, adhere to taking the 3-5 month, laboratory check renal function, blood urea nitrogen, creatinine recovers in normal value, and renal function recovers normal completely.
Collect case 20 example, the oldest 86 years, minimum 50 years old.There is hypertension 16 example, diabetes 3 example, lupus erythematosus disease 1 example.
Invalid 1 example: account for and collect 5% of case.This routine male patient 85 years old, with coronary heart disease, hypertension 3 grades, chronic nephritis, because edema is heavier, blood urea nitrogen is higher than 50, and creatinine, higher than 650, takes this " nephropathy healthy dispersion tablet " after two weeks, check renal function, display drug ineffective, blood urea nitrogen, creatinine is counter to be risen, and does not fall, and it is saturating that last western medical treatment does kidney.
Effective 19 examples, account for and collect 95% of case.Wherein cure 18 examples, account for and collect 90% of case.Wherein effectively but 1 example of not curing continues medication treatment, the 18 examples drug withdrawal of healing.
The Therapy characteristics of prescription of the present invention: state of an illness the lighter, treatment is cured the fastest, better.State of an illness severe one, the course for the treatment of is longer.Drug therapy renal insufficiency of the present invention, chronic kidney hypofunction disease are changed over, tonifying both YIN and YANG, based on nourishing YIN or blood circulation promoting and blood stasis dispelling, dampness removing the turbid descending thinking.Change into now, tonifying both YIN and YANG, the thinking based on YANG invigorating achieves good clinical therapeutic efficacy.
Medical record one:
Grandson XX, man, 50 years old, peasant, outpatient.
Patient: lumbago, cold extremities, frequent micturition January, carrys out out-patient treatment.
Suffer from chronic renal insufficiency, because of hypertension three grades, acute renal failure, treated to higher level's hospital, blood urea nitrogen 21.22, and creatinine 895, improvement is left hospital.
Existing dizzy, limbs fatigue.Two kidney percussion pain, two lower limb slight depression edema, face and eye edema, complexion is slightly dark, pale tongue and fat, deep pulse and late.
Laboratory examination renal function, blood urea nitrogen 7.22, creatinine 244.3, diagnosis: deficiency of spleen-YANG and kidneyYANG (renal insufficiency, chronic kidney hypofunction).
Control suitable kidney-replenishing, help kidney yang, subside a swelling as rule for the treatment of.
Side's medicine: nephropathy healthy dispersion tablet, takes two weeks, each 3-8 gram, every day 3 times, taking medicine after meal.Check renal function, is shown in laboratory test report, blood urea nitrogen 3.90, creatinine 133.4, compares with before two weeks, creatinine reduces 110.9, and blood urea nitrogen is normal.Continue to take the after treatment in three months of nephropathy healthy dispersion tablet, recovery from illness.
Medical record two:
Open XX, man, 86 years old, retired veteran cadre.
On August 25th, 2014 censorship result: blood urea nitrogen 11, creatinine 170, after an oral nephropathy healthy dispersion tablet treatment in month, namely JIUYUE in 2014 send check result to show on 25th, blood urea nitrogen 7.07, declines 3.93; Creatinine 133.6, declines 36.4.After treatment one month, drug withdrawal of now fully recovering.
Dispersible tablet of the present invention, tablet is light yellow, and gas fragrance is sweet.
Usage and dosage:
An oral 5-8g, three times on the one, one after each meal.
Untoward reaction:
Intestinal has slight stomachache, diarrhoea, day bowel movement three to four times, takes without drug withdrawal or decrement.
Points for attention:
Avoid fish and shrimp, fishy smell, pungent thing, wine and women-sensual pursuits.Less salt, low sugar, low fat diet.Anemia of pregnant woman is forbidden, and child reduces by half or follows the doctor's advice, and notes check renal function.
Prohibit with Rhizoma Pinelliae Preparata, Bulbus Fritillariae Uninbracteatae, Fructus Trichosanthis, Radix Ampelopsis, the Pseudobulbus Bletillae (Rhizoma Bletillae) with using.
Medicine is preserved should avoid high temperature and humidity.
The above embodiments are only the preferred technical solution of the present invention; and should not be considered as restriction of the present invention; the technical scheme that protection scope of the present invention should be recorded with claim, the equivalents comprising technical characteristic in the technical scheme of claim record is protection domain.Namely the equivalent replacement within the scope of this improves, also within protection scope of the present invention.
Claims (9)
1. be used for the treatment of a medicine for chronic renal insufficiency chronic kidney hypofunction disease, it is characterized in that comprising the following raw material with weight portion note:
Cornu Cervi Pantotrichum 70 ~ 90, Radix Aconiti Lateralis Preparata 17 ~ 23, Ramulus Cinnamomi 70 ~ 90, Herba Cistanches 170 ~ 230, Fructus Corni 170 ~ 230, Radix Rehmanniae Preparata 85 ~ 115, the Rhizoma Atractylodis Macrocephalae 170 ~ 230, Radix Angelicae Sinensis 170 ~ 230, the Radix Astragali 45 ~ 55.
2. a kind of medicine being used for the treatment of chronic renal insufficiency chronic kidney hypofunction disease according to claim 1, is characterized in that also comprising the following raw material with weight portion note:
Poria 170 ~ 230, Semen Plantaginis 170 ~ 230, Cortex Moutan 17 ~ 23.
3. a kind of medicine being used for the treatment of chronic renal insufficiency chronic kidney hypofunction disease according to claim 2, is characterized in that also adding the following raw material with weight portion note:
Radix Achyranthis Bidentatae 85 ~ 115, Radix Et Rhizoma Rhei 45 ~ 55.
4. a kind of medicine being used for the treatment of chronic renal insufficiency chronic kidney hypofunction disease according to claim 3, is characterized in that the following raw material by remembering with weight portion forms:
Cornu Cervi Pantotrichum 70, Radix Aconiti Lateralis Preparata 17, Ramulus Cinnamomi 70, Herba Cistanches 170, Fructus Corni 170, Radix Rehmanniae Preparata 85, the Rhizoma Atractylodis Macrocephalae 170, Radix Angelicae Sinensis 170, the Radix Astragali 45, Poria 170, Semen Plantaginis 170, Cortex Moutan 17, Radix Achyranthis Bidentatae 85, Radix Et Rhizoma Rhei 45.
5. a kind of medicine being used for the treatment of chronic renal insufficiency chronic kidney hypofunction disease according to claim 3, is characterized in that the following raw material by remembering with weight portion forms:
Cornu Cervi Pantotrichum 75, Radix Aconiti Lateralis Preparata 18, Ramulus Cinnamomi 85, Herba Cistanches 225, Fructus Corni 210, Radix Rehmanniae Preparata 105, the Rhizoma Atractylodis Macrocephalae 180, Radix Angelicae Sinensis 210, the Radix Astragali 51, Poria 185, Semen Plantaginis 205, Cortex Moutan 19, Radix Achyranthis Bidentatae 105, Radix Et Rhizoma Rhei 52.
6. a kind of medicine being used for the treatment of chronic renal insufficiency chronic kidney hypofunction disease according to claim 3, is characterized in that the following raw material by remembering with weight portion forms:
Cornu Cervi Pantotrichum 80, Radix Aconiti Lateralis Preparata 20, Ramulus Cinnamomi 80, Herba Cistanches 200, Fructus Corni 200, Radix Rehmanniae Preparata 100, the Rhizoma Atractylodis Macrocephalae 200, Radix Angelicae Sinensis 200, the Radix Astragali 50, Poria 200, Semen Plantaginis 200, Cortex Moutan 20, Radix Achyranthis Bidentatae 100, Radix Et Rhizoma Rhei 50.
7. a kind of medicine being used for the treatment of chronic renal insufficiency chronic kidney hypofunction disease according to claim 3, is characterized in that the following raw material by remembering with weight portion forms:
Cornu Cervi Pantotrichum 85, Radix Aconiti Lateralis Preparata 22, Ramulus Cinnamomi 88, Herba Cistanches 190, Fructus Corni 190, Radix Rehmanniae Preparata 90, the Rhizoma Atractylodis Macrocephalae 210, Radix Angelicae Sinensis 190, the Radix Astragali 48, Poria 220, Semen Plantaginis 220, Cortex Moutan 20, Radix Achyranthis Bidentatae 90, Radix Et Rhizoma Rhei 45.
8. a kind of medicine being used for the treatment of chronic renal insufficiency chronic kidney hypofunction disease according to claim 3, is characterized in that the following raw material by remembering with weight portion forms:
Cornu Cervi Pantotrichum 90, Radix Aconiti Lateralis Preparata 23, Ramulus Cinnamomi 90, Herba Cistanches 230, Fructus Corni 230, Radix Rehmanniae Preparata 115, the Rhizoma Atractylodis Macrocephalae 230, Radix Angelicae Sinensis 230, the Radix Astragali 55, Poria 230, Semen Plantaginis 230, Cortex Moutan 23, Radix Achyranthis Bidentatae 115, Radix Et Rhizoma Rhei 55.
9. a kind of medicine being used for the treatment of chronic renal insufficiency chronic kidney hypofunction disease according to claim 3, is characterized in that: after above raw material is cleaned impurity, oven dry, pulverizing, mix homogenously makes ball, capsule, sheet, granule, powder.
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| CN106266625B (en) * | 2015-05-21 | 2019-12-27 | 刘巍 | A Chinese medicinal composition for treating renal insufficiency, and its preparation method |
| CN105031413A (en) * | 2015-09-18 | 2015-11-11 | 全椒先奇医药科技有限公司 | Pharmaceutic preparation for treating chronic renal failure |
| CN105168664A (en) * | 2015-10-19 | 2015-12-23 | 管遵信 | Traditional Chinese medicine for treating chronic renal failure |
| CN105288272A (en) * | 2015-10-29 | 2016-02-03 | 张相才 | Formula for treating uremia and preparation method |
| CN105770318A (en) * | 2016-03-15 | 2016-07-20 | 董济嘉 | Chinese patent medicine formula for preventing and rehabilitating uremia and preparation method thereof |
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| CN102988728A (en) * | 2012-10-29 | 2013-03-27 | 严中明 | Chinese medicinal formulae for treating kidney deficiency type lumbar muscle degeneration |
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| 中医药治疗慢性肾衰竭研究进展;赵先锋;《现代中西医结合杂志》;20140131;第23卷(第2期);217－220页 * |
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