CN104545904A - Cognitive electroencephalogram (EEG) detection analysis method and device thereof - Google Patents
Cognitive electroencephalogram (EEG) detection analysis method and device thereof Download PDFInfo
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- CN104545904A CN104545904A CN201310511824.0A CN201310511824A CN104545904A CN 104545904 A CN104545904 A CN 104545904A CN 201310511824 A CN201310511824 A CN 201310511824A CN 104545904 A CN104545904 A CN 104545904A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/369—Electroencephalography [EEG]
- A61B5/377—Electroencephalography [EEG] using evoked responses
- A61B5/38—Acoustic or auditory stimuli
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/25—Bioelectric electrodes therefor
- A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
- A61B5/291—Bioelectric electrodes therefor specially adapted for particular uses for electroencephalography [EEG]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/40—Detecting, measuring or recording for evaluating the nervous system
- A61B5/4076—Diagnosing or monitoring particular conditions of the nervous system
- A61B5/4088—Diagnosing of monitoring cognitive diseases, e.g. Alzheimer, prion diseases or dementia
Abstract
The invention discloses a cognitive electroencephalogram (EEG) detection analysis method and a device thereof. The method comprises the following steps of performing cognitive EEG detection to obtain EEG data; making a subject complete a cognition task interactively in a simulation environment in order to obtain the time scale information and/or cognition state information of the cognition task; combining the EEG data with the time scale information and/or cognition state information of the cognition task; generating composite EEG information; performing cognitive EEG detection analysis according to the composite EEG information. The cognitive EEG detection analysis device comprises a detection module, an interaction module, a combination module, a generation module and a detection analysis module. Cognitive function detection and EEG information acquisition are performed synchronously, and cognitive function detection is tightly combined with EEG information in order to perform EEG detection analysis, so that controllability and flexibility are realized; moreover, man-machine interaction in the cognitive function detection is synchronously marked in the EEG information.
Description
Technical field
The present invention relates to detection analysis technical field, particularly relate to a kind of cognitive brain electro-detection analytical method and device thereof.
Background technology
The cognitive function of human body detects and detects with brain electricity EEG, and no matter both at home and abroad, be independent at all times and separate detection, shortcoming is also apparent.Cognitive function is only had to detect, no matter pure subjective scale or computerized subjective scale, lacks objectivity; Only have the EEG of normality to detect, quantity of information is thin, is difficult to maybe to distinguish the difference without between the patient of organic disease and normal person.By the detection of cognitive function, the quantity of information of strengthening and increasing EEG will be good outlet.Current brain electro-detection cannot be combined closely with the consciousness Cognitive task of experimenter, experimenter realize Cognitive task single and and uncontrollable, the consciousness Cognitive task state of the brain electric information gathered and experimenter and reaction also cannot synchronously contact, and cannot carry out more deep and numerous and diverse brain electricity analytical.
Summary of the invention
For the above-mentioned deficiency that cognitive brain electro-detection analysis exists, the object of this invention is to provide a kind of cognitive function to detect and synchronously carry out with brain electric information collection, cognitive function is detected combine closely with brain electric information, to carry out the analysis of brain electro-detection, there is controllability, motility.
For achieving the above object, embodiments of the invention adopt following technical scheme:
A kind of cognitive brain electro-detection analytical method, it is characterized in that, the method comprises:
Cognitive EEG detects, to obtain EEG data;
Experimenter's interactive cognitive task in simulated environment detects, to obtain time scale information and/or the cognitive Status information of Cognitive task;
The time scale information of combination EEG data and Cognitive task and/or cognitive Status information;
Generate combined type brain electric information;
According to combined type brain electric information, carry out the analysis of cognitive brain electro-detection.
According to one aspect of the present invention, wherein, described cognitive EEG detects and adopts active electrode EEG instrument or 24 to lead wireless blue tooth EEG detector to detect.
According to one aspect of the present invention, wherein, the kind of described Cognitive task is more than one, when interaction completes a certain Cognitive task to experimenter in simulated environment, is about to the time scale information and/or the cognitive Status information that obtain this Cognitive task corresponding.
According to one aspect of the present invention, wherein, described combined type brain electric information comprises the cognitive function detection point of the evaluation performance information of Cognitive task and this experimenter of generation.
The one that the embodiment of the present invention provides cognitive brain electro-detection analytical equipment, it is characterized in that, this device comprises:
Detection module, detects for cognitive EEG, to obtain EEG data;
Interactive module, for experimenter's interactive cognitive task in simulated environment, to obtain time scale information and/or the cognitive Status information of Cognitive task;
Composite module, for combining time scale information and/or the cognitive Status information of EEG data and Cognitive task;
Generation module, for generating combined type brain electric information;
Detect analysis module, for the detection analysis of cognitive brain electricity.
According to one aspect of the present invention, wherein, described detection module comprises active electrode EEG instrument or 24 and leads wireless blue tooth EEG detector.
According to one aspect of the present invention, wherein, the kind of described Cognitive task is more than one, when interaction completes a certain Cognitive task to experimenter in simulated environment, is about to the time scale information and/or the cognitive Status information that obtain this Cognitive task corresponding.
According to one aspect of the present invention, wherein, described generation module also comprises assessment module and the first generation unit, and described assessment module is for evaluating the performance information of Cognitive task, and described first generation unit detects for the cognitive function generating this experimenter and divides.
Embodiments of the invention adopt cognitive function to detect synchronously to carry out with brain electric information collection, cognitive function is detected combine closely with brain electric information, to carry out the analysis of brain electro-detection, there is controllability, motility, and the human-computer interaction during cognitive function detects carries out sync mark in brain electric information, carry out detection to the brain electric information under every Tasks state to analyze, for " reading brain " technology provides strong technical support.
Accompanying drawing explanation
In order to be illustrated more clearly in the technical scheme in the embodiment of the present invention, be briefly described to the accompanying drawing used required in embodiment below, apparently, accompanying drawing in the following describes is only some embodiments of the present invention, for those of ordinary skill in the art, under the prerequisite not paying creative work, other accompanying drawing can also be obtained according to these accompanying drawings.
Fig. 1 is the flow chart of a kind of cognitive brain electro-detection analytical method embodiment one of the present invention;
Detailed description of the invention
Below in conjunction with the accompanying drawing in the embodiment of the present invention, be clearly and completely described the technical scheme in the embodiment of the present invention, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
Embodiment one
As shown in Figure 1, the one that the present embodiment provides cognitive brain electro-detection analytical method, the method comprises:
Step S1: cognitive EEG detects, to obtain EEG data;
Experimenter carries out cognitive EEG detection, to gather acquisition EEG data.
Above-mentioned cognitive EEG detects and can detect by adopting active electrode EEG instrument, the action potential interference of eye electricity and head can be got rid of preferably, namely preamplifier is made in inside electrode without the need to EEG process described active electrode EEG instrument afterwards, namely such EEG instrument is called active electrode EEG instrument; Nation8128W-24WH type 24 can also be adopted to lead wireless blue tooth EEG detector detect, this detector is wireless EEG detector, preferably adopts Nation8128W-24WH type 24 to lead wireless blue tooth EEG detector.
Step S2: experimenter's interactive cognitive task in simulated environment detects, to obtain time scale information and/or the cognitive Status information of Cognitive task;
By display screen human-computer interaction, experimenter's interactive cognitive task in simulated environment detects, to obtain time scale information and/or the cognitive Status information of Cognitive task; The kind of described Cognitive task is more than one, when interaction completes a certain Cognitive task to experimenter in simulated environment, is about to the time scale information and/or the cognitive Status information that obtain this Cognitive task corresponding.
Step S1 and step S2 can order in no particular order, namely can synchronously carry out.
In the middle of practical application, through to the preliminary experiment of mid-aged population 10 person-times with repeatedly compare, the Cognitive task finally determined is 11:
1) computerized general Mini-Mental memory scale (MMSE), 8 minutes in limited time.
Standards of grading, with reference to classical subjective scale, judge also to duplicate, depend on schooling: more than illiteracy 17 points, 20 points, primary school, junior middle school 24 points, and actual measurement is point between 0-30.Because this is as 1 in 11 Cognitive tasks, and between 0-10 divides, therefore scoring=(actual measurement divides-17)/(30-17) * 10 after conversion, take absolute value.
What <=17 divided is considered as 0 point, and 30 points are considered as 10 points, object be pull open 17-30 divide between difference.
2) computerized international standard IQ test, extracts front 18 topics (mark IQ), 6 minutes in limited time.
Be divided into 3 grades by difficulty, every grade 6 topic, difficulty is from 1-3, and 6 topics random layout order in each detection of every grade, actual measurement point between 40-80 divides, in like manner, needs conversion.
Scoring after conversion=(actual measurement divides-40)/(80-40) * 10, takes absolute value.
3) round test is remembered-counted to numeral and two tasks of position, 2 minutes in limited time.
Require experimenter short term memory-in short-term and digital in the round position simultaneously occurred and circle, press Digital size subsequently, the ascending circle place is pointed out.If correct, the quantity of circle adds 1, otherwise heavily comes by former range.
4) delay memory-string test of numerical span, 2 minutes in limited time.
Require that experimenter is by after short term memory, by the numeric string just now heard or disappear again after seeing, repeat out accurately.If correct, the length of numeric string adds 1, otherwise heavily comes by former range.
5) delay memory-circle of position test of position range, 2 minutes in limited time.
Require experimenter short term memory-in short-term and all round position distributions simultaneously occurred, subsequently on the image basis just now remembered, the position at 1 round place of new interpolation is pointed out.If correct, the quantity of the circle simultaneously occurred adds 1, otherwise from the circle of minimum number, again comes.
6) simple digital operational capability test-computing test, 2 minutes in limited time.
After requiring that experimenter hears " equaling " sound or sees the equal sign of mathematic(al) representation, the numeral keys of operation result keypad is pressed out.Computer random is set a question, and records each correctness, and average used time and dispersion degree, provides the scoring between 0-10.
7) the Operational Figure Of Merit test-direction test of walking direction, 1.5 minutes in limited time.
Require that experimenter is by operating as soon as possible, by the arrow just now heard or disappear again after seeing, press 1 in upper and lower 4 keys in left and right on a keypad exactly.Computer random outgoing direction, records each correctness, and average used time and dispersion degree, provides the scoring between 0-10.Direction+for just to sentence, direction-sentence, under sentencing namely for inverse.
8) the understanding rate test-phrase test of phrase attribute, 1.5 minutes in limited time.
Research and develop voluntarily.Require that experimenter is by operating as soon as possible, by the yin-yang attribute of phrase just now heard or disappear again after seeing, in negative and positive 2 key on a keypad, press 1.As Wang Qiang=sun, Li Ju=the moon.Computer random goes out phrase, records each correctness, and average used time and dispersion degree, provides the scoring between 0-10.
9) statement judgement rate test right-statement test, 2 minutes in limited time.
Require that experimenter is by operating as soon as possible, by the correctness of statement just now heard or disappear again after seeing, on a keypad press 1 in wrong 2 keys.As " the ball side of being " " sun is from rising in the east ".Computer random goes out statement, records each correctness, and average used time and dispersion degree, provides the scoring between 0-10.
10) reaction sensitivity adds EEG auditory evoked potential CNV composition test, 8 minutes in limited time.
Require that experimenter enters alertness after the prompt tone hearing " preparations ", hear horse back button after the minor of several ms subsequently, then loosen rest, so circulate.Computer random gives " preparations " to the vigilance time of minor, records each correctness, and on average used time and dispersion degree, provides the scoring between 0-10.Meanwhile, carried out to the superposition of auditory evoked potential the vigilance time different in size by common length, totally 96 times, obtain the altricial part CNV of direct current of vigilance current potential.
11) EEG auditory evoked potential P300 parameter testing, 5 minutes in limited time.
Require that experimenter is in resting state, only need count the high pitch number of times heard, its accuracy can judge whether experimenter knocks and sleep, and determines the effectiveness of data.Computer sends out by the probability of 20% high pitch allowing people startle at random, and the probability of 80% is common bass, carries out superposition 99 times, obtain incubation period and the wave amplitude of P300 to the auditory evoked potential in 1 second that sends out not after unisonance.
Experimenter also can be allowed first to preview, formally start Cognitive task after previewing understanding again and detect.In addition, even if after formally starting, experimenter also can represent in operation " not counterweight come ", therefore also can interrupt at any time exiting and heavily come; Also after arbitrary Cognitive task terminates, can allow to come several times again, therefrom choose best once as " preferably " information of offical record.
Step S3: the time scale information of combination EEG data and Cognitive task and/or cognitive Status information;
After the time scale information obtaining EEG data and Cognitive task and/or cognitive Status information, time scale information and/or the cognitive Status information of the Cognitive task that the EEG data obtained by step S1 by combination type dedicated control system and step S2 are obtained start to combine.
Step S4: generate combined type brain electric information;
After the time scale information of the EEG data that step S1 obtains and the Cognitive task that step S2 obtains and/or cognitive Status information combine, generate combined type brain electric information, described combined type brain electric information comprises the cognitive function detection point of the evaluation performance information of Cognitive task and this experimenter of generation.
Step S5: according to combined type brain electric information, carries out the analysis of cognitive brain electro-detection.
According to combined type brain electric information, the analysis of cognitive brain electro-detection can be completed.
The one the provided cognitive brain electro-detection analytical equipment of the present embodiment, this device comprises: detection module, interactive module, composite module, generation module and detection analysis module, and described detection module, detects for cognitive EEG, to obtain EEG data; Described interactive module, for experimenter's interactive cognitive task in simulated environment, to obtain time scale information and/or the cognitive Status information of Cognitive task; Described composite module, for combining time scale information and/or the cognitive Status information of EEG data and Cognitive task; Described generation module, for generating combined type brain electric information;
Described detection analysis module, for the detection analysis of cognitive brain electricity.
Wherein, described detection module can be active electrode EEG instrument, also can be 24 to lead wireless blue tooth EEG detector.The kind of described Cognitive task is more than one, when interaction completes a certain Cognitive task to experimenter in simulated environment, is about to the time scale information and/or the cognitive Status information that obtain this Cognitive task corresponding.Described generation module also comprises assessment module and the first generation unit, and described assessment module is for evaluating the performance information of Cognitive task, and described first generation unit detects for the cognitive function generating this experimenter and divides.
The cognitive brain electro-detection analytical method of one of the embodiment of the present invention and device thereof, cognitive function can be realized detect and synchronously carry out with brain electric information collection, cognitive function is detected combine closely with brain electric information, to carry out the analysis of brain electro-detection, there is controllability, motility, and the human-computer interaction during cognitive function detects carries out sync mark in brain electric information, detection is carried out to the brain electric information under every Tasks state and analyzes, for " reading brain " technology provides strong technical support.
The above; be only the specific embodiment of the present invention, but protection scope of the present invention is not limited thereto, the technical staff of any skilled is in technical scope disclosed by the invention; the change that can expect easily or replacement, all should be encompassed within protection scope of the present invention.Therefore, protection scope of the present invention should be as the criterion with the protection domain of described claim.
Claims (8)
1. a cognitive brain electro-detection analytical method, it is characterized in that, the method comprises:
Cognitive EEG detects, to obtain EEG data;
Experimenter's interactive cognitive task in simulated environment detects, to obtain time scale information and/or the cognitive Status information of Cognitive task;
The time scale information of combination EEG data and Cognitive task and/or cognitive Status information;
Generate combined type brain electric information;
According to combined type brain electric information, carry out the analysis of cognitive brain electro-detection.
2. cognitive brain electro-detection analytical method according to claim 1, is characterized in that, described cognitive EEG detection adopts active electrode EEG instrument or 24 to lead wireless blue tooth EEG detector and detects.
3. cognitive brain electro-detection analytical method according to claim 1, it is characterized in that, the kind of described Cognitive task is more than one, when interaction completes a certain Cognitive task to experimenter in simulated environment, be about to the time scale information and/or the cognitive Status information that obtain this Cognitive task corresponding.
4. according to the cognitive brain electro-detection analytical method one of Claims 1-4 Suo Shu, it is characterized in that, described combined type brain electric information comprises the cognitive function detection point of the evaluation performance information of Cognitive task and this experimenter of generation.
5. a cognitive brain electro-detection analytical equipment, it is characterized in that, this device comprises:
Detection module, detects for cognitive EEG, to obtain EEG data;
Interactive module, for experimenter's interactive cognitive task in simulated environment, to obtain time scale information and/or the cognitive Status information of Cognitive task;
Composite module, for combining time scale information and/or the cognitive Status information of EEG data and Cognitive task;
Generation module, for generating combined type brain electric information;
Detect analysis module, for the detection analysis of cognitive brain electricity.
6. cognitive brain electro-detection analytical equipment according to claim 5, is characterized in that, described detection module comprises active electrode EEG instrument or 24 and leads wireless blue tooth EEG detector.
7. cognitive brain electro-detection analytical equipment according to claim 6, it is characterized in that, the kind of described Cognitive task is more than one, when interaction completes a certain Cognitive task to experimenter in simulated environment, be about to the time scale information and/or the cognitive Status information that obtain this Cognitive task corresponding.
8. according to the cognitive brain electro-detection analytical equipment one of claim 5 to 7 Suo Shu, it is characterized in that, described generation module also comprises assessment module and the first generation unit, described assessment module is for evaluating the performance information of Cognitive task, and described first generation unit detects for the cognitive function generating this experimenter and divides.
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