CN104545893B - The method recognized to the true and false of the QRS wave in the FECG of separation - Google Patents
The method recognized to the true and false of the QRS wave in the FECG of separation Download PDFInfo
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- CN104545893B CN104545893B CN201510017408.4A CN201510017408A CN104545893B CN 104545893 B CN104545893 B CN 104545893B CN 201510017408 A CN201510017408 A CN 201510017408A CN 104545893 B CN104545893 B CN 104545893B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
- A61B5/344—Foetal cardiography
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
- A61B5/346—Analysis of electrocardiograms
- A61B5/349—Detecting specific parameters of the electrocardiograph cycle
- A61B5/366—Detecting abnormal QRS complex, e.g. widening
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7271—Specific aspects of physiological measurement analysis
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Abstract
The present invention relates to a kind of method that easily can be recognized to the true and false of the QRS wave in the FECG of separation, it includes three steps, (1) detect or read the wall of the chest electric signal for separating the stomach wall electric signal of fetal electrocardiogram and helping out, (2) separation of FECG is realized using certain algorithm, (3) by separating resulting, with reference to original signal, show on the computer screen or printed on a sheet of paper in some way, the true and false of the FECG QRS wave of separation is recognized accordingly；It is characterized in that, the oscillogram that (3) step shows will at least include the oscillogram of stomach wall electric signal waveform figure and isolated each FECG all the way, and to be arranged above and below during their arrangements, abscissa (i.e. time shaft) length of all oscillograms is identical, scale is identical, starting point will align, there is the equidistant grid lines in longitudinal direction in all oscillograms, the quantity of the longitudinal network ruling on different wave figure is equal, interval is identical.
Description
Technical field
What the true and false that the application is related to the QRS wave in a kind of FECG that easily can be obtained to separation was recognized
Method.
As be grown up all have an electro-cardiogram inspection, fetus also has the necessity for inspection of having an electro-cardiogram.Noninvasive non-intrusion type
Fetal rhythm electro-detection, electrode is disposed primarily in pregnant woman's stomach wall to detect, the stomach wall electricity of record not only contains fetal electrocardiogram composition, also wrapped
Parent electrocardio composition is contained and other interference noises, signal to noise ratio is very low.It is existing it is clinical fetal electrocardiograph, only note
The stomach wall electricity of record prints to be seen for doctor, does not separate fetal electrocardiogram, it is impossible to is calculated Fetal Heart Rate automatically, might as well be referred to as first generation fetus
Electrocardiograph.What people were studying now is the fetal electrocardiograph for having female fetal electrocardiogram separation function, it is desirable to by separating energy
Improve the signal to noise ratio of FECG and calculate Fetal Heart Rate automatically, the fetal electrocardiograph for having separation function might as well be called new one
For fetal electrocardiograph.
Fetal electrocardiograph of new generation also has many problems to solve to clinical practice is eventually entered into.One problem is：By
In various reasons, although the more former stomach wall electric signal signal to noise ratio of isolated FECG improves on the whole, but count automatically
The Fetal Heart Rate that is correctly averaged is calculated, but some exceptions are there will still likely be in FECG waveform, some wave bands for seeming QRS wave are real
Border is not real fetal electrocardiogram QRS wave, is parent electrocardio or the residual of other interference noises, and some on waveform should be gone out
QRS wave is can't see at the position of existing fetal electrocardiogram QRS wave again, and we might as well be referred to as both of these case the artefact of fetal electrocardiogram QRS wave
(being called artifact, artifact).Therefore, in order that doctor occurs without mistaken diagnosis, the QRS wave in the FECG obtained to separation
The true and false firstly there are one identification the problem of.
Background technology
The true and false of the QRS wave in FECG is distinguished, first has to isolate FECG certainly.Though do not enter now
Enter the fetal electrocardiograph of new generation with separation function of Clinical practice, but study the document of FECG isolation technics still
Many.Isolating fetal electrocardiogram, there is the electricity of stomach wall all the way from detection to realize separation, also there is a few road stomach walls electricity from detection
Separation is realized by fusion calculation, increase is all the way when also detecting or a few road wall of the chest electricity separate to help to stomach wall electricity
's.
In document, the presentation mode of various fetal electrocardiogram separation algorithm results also has difference：If it is directed to multichannel abdomen
The processing method of wall electricity (wall of the chest electricity can be contained), such as Independent component analysis (ICA), then usually by isolated each Lu Yuanxin
Number it is arranged in order by separation order；If for the processing method of single channel stomach wall electricity, then may by road stomach wall electricity, separate
Maternal ecg, the isolated FECG arrived arranges together, also draws their frequency spectrum together sometimes.
The presentation mode of the result of various fetal electrocardiogram separation algorithms, generally speaking, is not examined in present document
Consider so much, it appears that how is the whole structure for the FECG for being intended to only to allow reader to have a look separation, to judge what is proposed
Separation method, do not account for clinically there are the needs distinguished the true and false of each QRS wave of the FECG of separation,
Therefore, also have no that the corresponding technology for proposing to be suitable to easily can clinically recognize the FECG QRS wave true and false is arranged
Apply or scheme.
Bibliography：
1. Han Liang, Pu Xiujuan：Using time-frequency blind source separating and the Fetal ECG signal extraction of wavelet packet denoising, computer should
With 2013,33 (8)：2394-2396,2400.
2.Shuicai Wu, Yanni Shen, Zhuhuang Zhou, Lan Lin, Yanjun Zeng, Xiaofeng
Gao：Research of fetal ECG extraction using wavelet analysis and adaptive
Filtering, 2013, Computers in Biology and Medicine, 43：pp.1622-1627
The content of the invention
Goal of the invention.
It is proposed a kind of technical side suitable for easily can clinically be recognized to the FECG QRS wave true and false of separation
Case.
Technical scheme.
The present invention relates to a kind of side that easily can be recognized to the true and false of the QRS wave in the FECG of separation
Method, it includes three steps, and the wall of the chest electricity for separating the stomach wall electric signal of fetal electrocardiogram and helping out is detected or read in (1)
Signal, do not have to not detect or read wall of the chest electricity if the wall of the chest is electrically assisted if separation method, (2) realize the fetus heart using certain algorithm
The separation of electrograph, i.e., a FECG is at least calculated, corresponding N number of FECG is calculated to N born of the same parents' tire, while can
Calculate a maternal ecg, separating resulting with reference to original detection or is read signal, be shown in calculating in some way by (3)
On machine screen or print on a sheet of paper, the true and false of the FECG QRS wave of separation is recognized accordingly by clinical staff；
It is characterized in that when (3) step shows on the computer screen or printed on a sheet of paper, the oscillogram to be showed will at least include
The oscillogram of stomach wall electric signal waveform figure and isolated each FECG all the way, and to be arranged up and down during their arrangements
Row, abscissa (i.e. time shaft) length of all oscillograms is identical, scale is identical, starting point will align, in all oscillograms
There is an equidistant grid lines in longitudinal direction, the quantity of the longitudinal network ruling on different wave figure is equal, interval is identical.
Above scheme is the utilization and embodiment of human vision rule and law of cognition, also reflects FECG QRS wave
The objective requirement of identification.
Beneficial effect
At present, there is not yet document proposes easily to distinguish the true and false of the QRS wave in the FECG of separation
The technical scheme of knowledge, therefore, the technical program has novelty.Fig. 2 is the oscillogram of an isolated FECG,
With the presence of puppet fetus QRS wave at two on this Fetal ECG waveform individually showed, see that arrow a and b are signified in Fig. 2, their essence
For the residual of parent electrocardio QRS wave, but clinical staff can not judge that they are the heart murmur phenomenon of fetus or pseudo- tire on earth
Youngster's QRS wave.Fig. 3 is situation about showing the FECG of stomach wall electric signal all the way and separation together by the technical program, on
Portion is stomach wall electrical waveform figure, and bottom is the Fetal ECG oscillogram of separation, it is clear that clinical by compareing up and down by grid lines
Personnel are easy to recognize the true and false of fetus QRS wave；Specifically, by compareing up and down, easily find out at the c and h of FECG not
It is real fetus QRS wave, is artefact, they are actually the residual of the parent signal at top stomach wall electricity a and f respectively, and
Fetus QRS wave should be shown at the d and g of FECG, because can be seen at the correspondence position b and e of stomach wall electrical waveform
See and be superimposed with slight fetus QRS wave, but separating resulting misses fetus QRS wave, and this is also artefact.Fig. 4 is from top to bottom successively
For the former electricity of the wall of the chest all the way detected, the electricity of stomach wall all the way selected, the maternal ecg separated, the FECG separated, it is clear that
By the way that by them, proper alignment is shown together up and down, by grid lines, the QRS wave being also easily discernible in the FECG of separation
The true and false, this also belongs to one of concrete condition of the technical program.The table of reporting situations of test and tester by mass data
Bright, the technical program is highly effective to the true and false of the QRS wave in the FECG of identification extraction, very practical, with individually presenting
FECG, which is recognized or recognize comparing without grid lines, substantive progress.
Brief description of the drawings
Fig. 1, the FB(flow block) of the technical program
Fig. 2, identification schematic diagram is not easy when FECG is individually presented
Fig. 3, identification schematic diagram when stomach wall electric signal all the way and the FECG separated is presented by this programme
Fig. 4, identification schematic diagram during four road waveforms is presented by this programme
Fig. 5, the presentation result by this programme to twins' situation
Embodiment (embodiment)
There are the data of a twins pregnant woman, including the 1 tunnel pregnant woman's wall of the chest electric signal synchronously detected and 3 in clinical detection record
Road stomach wall electric signal, sample frequency 1kHz.
First, the road signal of pregnant woman four of record is read.(2) step, a parent is isolated successively using literature method
Electrocardiogram and the FECG of two fetuses.(3) step, the 1 obvious stomach wall electric signal of tunnel fetal electrocardiogram composition is selected with separating
An obtained maternal ecg and two FECGs shows on the computer screen or printed on a sheet of paper, allows them
It is arranged above and below successively, abscissa (i.e. time shaft) length of four oscillograms is identical, scale is identical, starting point alignment, in oscillogram
There is an equidistant grid lines in longitudinal direction, the quantity of the longitudinal network ruling on different wave figure is equal, interval is identical, as shown in Figure 5.From figure
In 5, it is convenient to identify the true and false of the QRS wave of two FECGs；For example, easily find a fetus of bottom displaying
Be pseudo- fetus QRS wave at the c of electrocardiogram, it is actually at stomach wall electricity a caused by the residual of signal, and be at d should
There is a fetus QRS wave, but miss, because being superimposed with a fetus QRS wave at stomach wall electricity correspondence position b.
Claims (1)
1. a kind of method that easily can be recognized to the true and false of the QRS wave in the FECG of separation, including three steps
Suddenly, the wall of the chest electric signal for separating the stomach wall electric signal of fetal electrocardiogram and helping out is detected or read in (1), if separation method
Assist then not detecting or read wall of the chest electric signal without wall of the chest electric signal, (2) realize the separation of FECG, at least calculate
Go out a FECG, corresponding N number of FECG calculated to N born of the same parents' tire, while a maternal ecg can be calculated,
(3) by separating resulting, with reference to original detection or signal is read, shows on the computer screen or prints on a sheet of paper, by clinic
Personnel recognize to the true and false of the FECG QRS wave of separation accordingly；Characterized in that, (3) step is shown in computer
On screen or when printing on a sheet of paper, the oscillogram to be showed will at least include stomach wall electric signal waveform figure all the way and separate
The oscillogram of each FECG arrived, and to be arranged above and below during their arrangements, the abscissa of all oscillograms, that is,
Time shaft, length is identical, scale is identical, starting point will align, and to have the equidistant grid lines in longitudinal direction in all oscillograms, different
The quantity of longitudinal network ruling in oscillogram is equal, interval is identical.
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105411577B (en) * | 2015-12-30 | 2019-06-04 | 深圳先进技术研究院 | Fetal ECG signal separating method and system |
| CN109645985B (en) * | 2019-02-22 | 2021-09-17 | 南京大学 | Method for detecting single-channel electrocardiogram R peak of abdominal wall electrogynae body of pregnant woman |
| CN113223672B (en) * | 2020-01-20 | 2023-11-10 | 深圳市理邦精密仪器股份有限公司 | Electrocardiographic waveform measuring method, and related equipment and device |
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| US5666959A (en) * | 1995-08-30 | 1997-09-16 | British Technology Group Limited | Fetal heart rate monitoring |
| WO2010058230A2 (en) * | 2008-11-24 | 2010-05-27 | Institut Rudjer Boskovic | Method of and system for blind extraction of more than two pure components out of spectroscopic or spectrometric measurements of only two mixtures by means of sparse component analysis |
| CN102090888A (en) * | 2011-03-30 | 2011-06-15 | 南京大学 | Method for separating and extracting fetal electrocardiogram by adopting multi-lead signal fusion mode |
| CN102178522A (en) * | 2011-04-29 | 2011-09-14 | 华南理工大学 | Method for detecting and locating R wave in QRS (Quantum Resonance Spectrometer) waves of electrocardiographic signals of mother and fetus |
| CN102525452A (en) * | 2011-10-19 | 2012-07-04 | 广东工业大学 | Single-channel fetal electrocardiogram blind separation device based on oblique projection and separation method |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8064991B2 (en) * | 2008-01-08 | 2011-11-22 | The General Electric Company | Method of fetal and maternal ECG identification across multiple EPOCHS |
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Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5666959A (en) * | 1995-08-30 | 1997-09-16 | British Technology Group Limited | Fetal heart rate monitoring |
| WO2010058230A2 (en) * | 2008-11-24 | 2010-05-27 | Institut Rudjer Boskovic | Method of and system for blind extraction of more than two pure components out of spectroscopic or spectrometric measurements of only two mixtures by means of sparse component analysis |
| CN102090888A (en) * | 2011-03-30 | 2011-06-15 | 南京大学 | Method for separating and extracting fetal electrocardiogram by adopting multi-lead signal fusion mode |
| CN102178522A (en) * | 2011-04-29 | 2011-09-14 | 华南理工大学 | Method for detecting and locating R wave in QRS (Quantum Resonance Spectrometer) waves of electrocardiographic signals of mother and fetus |
| CN102525452A (en) * | 2011-10-19 | 2012-07-04 | 广东工业大学 | Single-channel fetal electrocardiogram blind separation device based on oblique projection and separation method |
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