CN104530471B - A kind of discoloration method of dye gelatin soft capsule shell waste material - Google Patents
A kind of discoloration method of dye gelatin soft capsule shell waste material Download PDFInfo
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- CN104530471B CN104530471B CN201510033278.3A CN201510033278A CN104530471B CN 104530471 B CN104530471 B CN 104530471B CN 201510033278 A CN201510033278 A CN 201510033278A CN 104530471 B CN104530471 B CN 104530471B
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Abstract
The invention discloses a kind of discoloration method of dye gelatin soft capsule shell waste material, comprise the following steps：（1）The preparation of polyacrylamide solution；（2）The preparation of the dye gelatin soft capsule shell waste material aqueous solution；（3）Flocculation clarifying treatment.The discoloration method of dye gelatin soft capsule shell waste material of the present invention being capable of the original gelatin characteristic of reduction stain soft-gelatin softgel shell waste material most possibly, handled obtained gelatin glue is filtered, sterilizing, freeze forming, drying, after crushing, the gelatin containing a small amount of glycerine can be reduced into, the recovery of its main physical and chemical index is due to the intervention of glycerine, it can increased than pure gelatin, other indexs can also reach pharmagel standard, moreover, the discoloration method of dye gelatin hard capsule case waste material of the present invention, which also has, improves the gelatin rate of recovery, it is cost-effective, the meaning of environmental protection, it is simultaneously simple with technique, it is economic and practical, the advantages of steady quality.
Description
Technical field
The present invention relates to gelatine capsule technical field, relates in particular to a kind of decolouring of dye gelatin soft capsule shell waste material
Method.
Background technology
Capsule includes hard shell capsules and soft capsule, soft capsule be liquid medicine or juicy fruit body medicine are sealed in through processing it is soft
Manufactured a kind of capsule in capsule material, the capsule shells of soft capsule are by gelatinum pro capsulae, glycerine or other are suitable medicinal auxiliary
Material list is only or is mixed, and ingredient and hard capsule case are substantially similar in soft capsule shell, are mainly wrapped in the synthetic of its softgel shell
Include and meet 2010《Chinese Pharmacopoeia》The gelatin of gelatinum pro capsulae standard, plasticizer,Water, the class material of additives four.
Gelatin is the skin of animal, in bone, tendon and ligament collagen through appropriate hydrolysis (acid system, alkaline process, soda acid mixing method or
Enzyme process) obtained product, or the mixture of above-mentioned different gelatin products are purified afterwards.
With the development of China's medical industry and increasing for pharmaceutical production manufacturer, current national capsule shells produce 1000000000000 per year；
249 production firms；1000 production lines；Percent defective has substantial amounts of soft-gelatin softgel shell waste product to produce 5% or so every year,
Wherein most can not be recycled because dyed, greatly waste resource, and because gelatin is in acid, alkali, enzyme, warm
In the presence of easily degrade, cause these dye gelatin soft capsule shells decolourize after Quality Down, it is impossible to utilized well, because
This is badly in need of a kind of discoloration method for being capable of the original gelatin characteristic of reduction stain soft-gelatin softgel shell waste material.
The content of the invention
It is simple that the technical problems to be solved by the invention are to provide a kind of environmental protection, technique, economic and practical, the energy of steady quality
The discoloration method of the dye gelatin soft capsule shell waste material of the original gelatin characteristic of enough reduction stain soft-gelatin softgel shell waste materials.
In order to solve the above-mentioned technical problem, the present invention provides the discoloration method of two kinds of dye gelatin soft capsule shell waste materials：
The discoloration method of the first dye gelatin soft capsule shell waste material, comprises the following steps：
(1) preparation of polyacrylamide solution
Polyacrylamide is weighed, water is added in polyacrylamide, stirs to polyacrylamide to be completely dissolved and produces poly- third
The acrylamide aqueous solution, it is standby；
The addition of the water is to enable to polyacrylamide to be completely dissolved；
(2) preparation of the dye gelatin soft capsule shell waste material aqueous solution
Dye gelatin soft capsule shell waste material is weighed, water is added in dye gelatin soft capsule shell waste material, is stood bright to dyeing
Glue soft capsule shell waste material expands completely, is then uniformly heated said mixture under conditions of 35-85 DEG C, to dyeing
Soft-gelatin softgel shell waste material, which is completely dissolved, produces the dye gelatin soft capsule shell waste material aqueous solution；
The addition of the water is enables to dye gelatin soft capsule shell waste material to be completely dissolved and makes dye gelatin flexible glue
The concentration of the softgel shell waste material aqueous solution is 1% -25%；
(3) flocculation clarifying treatment
With the polyacrylamide solution obtained by adsorptivity flocculation aid and step (1) to the dye gelatin obtained by step (2)
The soft capsule shell waste material aqueous solution carries out the flocculation and the processing of subsequent separation supernatant more than once or twice, until isolated
Supernatant be in glassy yellow clarification liquid, should be gelatin glue in supernatant of clarification liquid of glassy yellow.
The discoloration method of second of dye gelatin soft capsule shell waste material, comprises the following steps：
(1) preparation of polyacrylamide solution
Polyacrylamide is weighed, water is added in polyacrylamide, stirs to polyacrylamide to be completely dissolved and produces poly- third
The acrylamide aqueous solution, it is standby；
The addition of the water is to enable to polyacrylamide to be completely dissolved；
(2) preparation of the dye gelatin soft capsule shell waste material aqueous solution
Dye gelatin soft capsule shell waste material is weighed, water is added in dye gelatin soft capsule shell waste material, is stood bright to dyeing
Glue soft capsule shell waste material expands completely, is then uniformly heated said mixture under conditions of 35-85 DEG C, to dyeing
Soft-gelatin softgel shell waste material, which is completely dissolved, produces the dye gelatin soft capsule shell waste material aqueous solution；
The addition of the water is enables to dye gelatin soft capsule shell waste material to be completely dissolved and makes dye gelatin flexible glue
The concentration of the softgel shell waste material aqueous solution is 1% -25%；
(3) activated carbon decolorizing filtration treatment
Above activated carbon decolorizing once or twice is carried out to the dye gelatin hard capsule case waste material aqueous solution obtained by step (2)
With subsequent filtration treatment, the filtrate obtained after filtering is in the red muddy liquid of skin；
(4) flocculation clarifying treatment
The filtrate obtained by step (3) is carried out with the polyacrylamide solution obtained by adsorptivity flocculation aid and step (1)
Flocculation and subsequent separation supernatant more than once or twice are handled, until isolated supernatant is in the clarification of glassy yellow
Liquid, should be gelatin glue in the supernatant of the clarification liquid of glassy yellow.
Water of the present invention is preferably deionized water.
The concentration is mass percent concentration.
The uniform heating pattern has the conventional uniform heating patterns such as water-bath, oil bath, coil pipe heating.
The adsorptivity flocculation aid can improve flocculent structure greatly or with three-dimensional space with surface area, such as high clay, silicon
Diatomaceous earth, perlite or atlapulgite etc..Adsorptivity flocculation aid plays cohesive crane span structure between tiny flocculation, makes flocculation thick and by wide
Wealthy surface, absorption winding effect is given full play to, to improve decolouring clarifying effect.
The discoloration method of second of dye gelatin soft capsule shell waste material provided by the invention is soft in the first dye gelatin
Activated carbon decolorizing filtration treatment step is added on the basis of the discoloration method of capsule shells waste material, the activated carbon is also known as activated carbon
It is black, activated carbon be a kind of black powdery, it is granular or pellet it is amorphous there is porous carbon, there is larger surface area, pass through
Intermolecular force adsorbs the impurity such as the pigment on its surface, so as to have the function that adsorption bleaching, in second of dye of the present invention
Used in the discoloration method of color soft-gelatin softgel shell waste material as decolorising agent, the color of dye gelatin soft capsule shell waste material dye is got over
Weight, the concentration of the dye gelatin soft capsule shell waste material aqueous solution is bigger, and the usage amount of activated carbon is more, can make dyeing with activated carbon
The decolouring of soft-gelatin softgel shell waste material is more thorough, and reduces the number of follow-up flocculation clarifying treatment.The activated carbon decolorizing and with
The process per treatment of filtration treatment afterwards is：Activated carbon is added into the solution of required decolouring under stirring condition, continues to stir
More than 30min is mixed, activated carbon is merged completely with the solution of required decolouring, is then filtered.
The polyacrylamide, it is a kind of linear polymer for being dissolved in water, is on the one hand made by polyacrylamide
Macromolecular chain mutually twines crosslinking, is formed and built bridge, so that flocculent structure increase is thicker, forms precipitation；On the other hand high clay, diatom
Soil can provide substantial amounts of complex ion, and can strong adsorption suspension particulate, by absorption, crane span structure, crosslinked action so that
Suspension condenses, and forms precipitation, is used in the present invention as flocculant.
The process per treatment that the flocculation and subsequent separation supernatant are handled is：By the molten of required flocculation clarifying treatment
Liquid is uniformly heated under conditions of 35-85 DEG C, is added and is adsorbed into the solution of required flocculation clarifying treatment under stirring condition
Property flocculation aid, continue stirring merges completely to adsorptivity flocculation aid with the required solution for flocculating clarifying treatment, then stirring condition
The lower polyacrylamide solution being continuously added into said mixture obtained by step (1), until stopping adding after flocculation completely
The flocculation liquid of polyacrylamide solution, will flocculation liquid stand it is complete to flocculating setting, finally by the complete gelatin of flocculating setting
The supernatant of flocculation liquid is separated.Without activated carbon decolorizing, only pass through flocculation once or twice above and subsequent separation
Supernatant processing directly can also remove the color of dye gelatin soft capsule shell waste material and impurity, and can be made using activated carbon
The decolouring of dye gelatin soft capsule shell waste material is more thorough, and reduces the number of follow-up flocculation clarifying treatment.
The dye gelatin soft capsule shell waste material is to produce waste material, leftover pieces etc. caused by dye gelatin soft capsule shell,
Dye gelatin soft capsule shell individually or is mixed, soft capsule by gelatinum pro capsulae, glycerine or other suitable pharmaceutic adjuvants
Ingredient and hard capsule case are substantially similar in shell, main in the synthetic of its softgel shell to include meeting 2010《Chinese Pharmacopoeia》Capsule
With the gelatin of gelatin standard, plasticizer, water, the class material of additives four.
The supernatant that present invention flocculation clarifying treatment obtains is in the clarification liquid of glassy yellow, should be in the clarification liquid of glassy yellow
Supernatant be gelatin glue, and it is deposited in the flocculation residue of bottom, can be reused in 24 hours, most pass through afterwards from
After the filter method such as the heart or suction filtration or press filtration sloughs the gelatin glue contained by it, turn into pie and discard, so handle it is more environmentally-friendly,
And improve resource utilization.
The present invention clarifies by using the flocculation of activated carbon decolorizing filtration treatment and polyacrylamide and adsorptivity flocculation aid
The steps such as processing, can be by the colour removal of dye gelatin soft capsule shell waste material, and by impurity such as plasticizer, additives also in the lump
Remove.The characteristic of gelatin is can be directly dissolved in hot water (gelatin about dissolves at 30 DEG C), insoluble in cold water but can absorb 5-
The cold water of 10 times of quality and expand, dissolved again in the water of warm after expansion, such dissolution velocity faster, can as far as possible avoid gelatin
Thermal degradation, be advantageous to protect gelatin quality, and agents useful for same of the present invention and technique are not involved with acid, alkali, enzyme and high temperature
It is short etc. factor, operating time, it can reduce the degraded of gelatin to greatest extent, therefore dye gelatin soft capsule shell waste material of the present invention
Discoloration method can the original gelatin characteristic of reduction stain soft-gelatin softgel shell waste material most possibly, handled obtained gelatin
Glue is filtered, sterilizing, freeze forming, drying, after crushing, can be reduced into the gelatin containing a small amount of glycerine, it is mainly managed
Change the recovery of index (viscosity, freezing power) due to the intervention of glycerine, can increased than pure gelatin, other indexs can also reach
To pharmagel standard.Moreover, the discoloration method of dye gelatin soft capsule shell waste material of the present invention, which also has, improves gelatin recovery
Rate, cost-effective, environmental protection meaning, while simple with technique is economic and practical, is a kind of the advantages of steady quality
Very effective dye gelatin soft capsule shell waste recovery processing method.
As the first of the invention dye gelatin soft capsule shell waste material discoloration method it is preferred, with adsorptivity flocculation aid and
Polyacrylamide solution obtained by step (1) carries out one to the dye gelatin soft capsule shell waste material aqueous solution obtained by step (2)
Secondary flocculation and subsequent separation supernatant are handled, and processing procedure is：By the dye gelatin soft capsule shell rejected water obtained by step (2)
Solution is uniformly heated under conditions of 35-85 DEG C, is added under stirring condition into the dye gelatin soft capsule shell waste material aqueous solution
Enter adsorptivity flocculation aid, the addition of adsorptivity flocculation aid is more than the 65% of dye gelatin soft capsule shell waste material quality, is continued
Stirring is merged completely to adsorptivity flocculation aid with the dye gelatin soft capsule shell waste material aqueous solution, then to above-mentioned mixed under stirring condition
The polyacrylamide solution obtained by step (1) is continuously added in compound, until stopping adding polyacrylamide after flocculation completely
The aqueous solution must be flocculated liquid, and flocculation liquid is stood into, the supernatant of finally flocculating setting completely flocculates liquid complete to flocculating setting
Separate, isolated supernatant is in the clarification liquid of glassy yellow, should be in the supernatant of the clarification liquid of glassy yellow
Gelatin glue.Step and time can be saved by only carrying out once flocculation and the processing of subsequent separation supernatant, reduce the heat of gelatin
Degraded, preferably protect gelatin quality.
As the first of the invention dye gelatin soft capsule shell waste material discoloration method it is preferred, with adsorptivity flocculation aid and
Polyacrylamide solution obtained by step (1) carries out two to the dye gelatin soft capsule shell waste material aqueous solution obtained by step (2)
Secondary flocculation and subsequent separation supernatant are handled, and processing procedure is：By the dye gelatin soft capsule shell rejected water obtained by step (2)
Solution is uniformly heated under conditions of 35-85 DEG C, is added under stirring condition into the dye gelatin soft capsule shell waste material aqueous solution
Entering adsorptivity flocculation aid, the addition of adsorptivity flocculation aid is 40%-the 55% of dye gelatin soft capsule shell waste material quality, after
Continuous stirring is merged completely to adsorptivity flocculation aid with the dye gelatin soft capsule shell waste material aqueous solution, then to above-mentioned under stirring condition
The polyacrylamide solution obtained by step (1) is continuously added in mixture, until stopping adding polyacrylamide after flocculation completely
Amine aqueous solution must be flocculated liquid, and flocculation liquid is stood into, the supernatant of finally flocculating setting completely flocculates liquid complete to flocculating setting
Liquid is separated as first separation liquid；First separation liquid is uniformly heated under conditions of 35-85 DEG C, stirring condition
Adsorptivity flocculation aid is added in the lower liquid to first separation, the addition of adsorptivity flocculation aid is dye gelatin soft capsule shell waste material matter
25%-the 30% of amount, continue stirring and merged completely with first separation liquid to adsorptivity flocculation aid, then under stirring condition upwards
State and polyacrylamide solution obtained by step (1) is continuously added in mixture, until stopping adding polypropylene after flocculation completely
Amide aqueous solution obtains the flocculation liquid of first separation liquid, the flocculation liquid of first separation liquid is stood it is complete to flocculating setting, finally will
The supernatant of the flocculation liquid of the complete first separation liquid of flocculating setting is separated, and isolated supernatant is clear in glassy yellow
Clear liquid shape, should be gelatin glue in the supernatant of the clarification liquid of glassy yellow.Carry out flocculation twice and subsequent separation supernatant
Liquid processing, although adding step and time, can avoid disposably adding excessive adsorptivity flocculation aid, be inhaled so as to reduce
The usage amount of attached property flocculation aid, reduces cost.
As second of dye gelatin soft capsule shell waste material of the invention discoloration method it is preferred, to obtained by step (2)
The dye gelatin soft capsule shell waste material aqueous solution carries out an activated carbon decolorizing and subsequent filtration treatment, processing procedure are：Stirring
Under the conditions of activated carbon is added into the dye gelatin soft capsule shell waste material aqueous solution, the addition of activated carbon is dye gelatin soft capsule
More than the 30% of shell waste material quality, continue to stir more than 30min, make activated carbon and the dye gelatin soft capsule shell waste material aqueous solution complete
Full fusion, is then filtered said mixture, and the filtrate obtained after filtering is in the red muddy liquid of skin.Only carry out once
Activated carbon decolorizing processing can save step and time, reduce the thermal degradation of gelatin, preferably protect gelatin quality.
As second of dye gelatin soft capsule shell waste material of the invention discoloration method it is preferred, to obtained by step (2)
Activated carbon decolorizing and subsequent filtration treatment, processing procedure are the progress of the dye gelatin soft capsule shell waste material aqueous solution twice：Stirring
Under the conditions of activated carbon is added into the dye gelatin soft capsule shell waste material aqueous solution, the addition of activated carbon is dye gelatin soft capsule
20%-the 40% of shell waste material quality, continue to stir more than 30min, make activated carbon and the dye gelatin soft capsule shell waste material aqueous solution
Fusion completely, then carries out said mixture to filter to obtain first-time filtrate；Activated carbon is added under stirring condition into first-time filtrate,
The addition of activated carbon is 1%-the 30% of dye gelatin soft capsule shell waste material quality, continues to stir more than 30min, makes activity
Charcoal merges completely with first-time filtrate, is then filtered said mixture, and the filtrate obtained after filtering is in the red muddiness of skin
Liquid.Carry out activated carbon decolorizing twice to handle, although adding step and time, can avoid disposably adding excessive work
Property charcoal, so as to reduce the usage amount of activated carbon, reduces cost.
As second of dye gelatin soft capsule shell waste material of the invention discoloration method it is preferred, with adsorptivity flocculation aid and
Polyacrylamide solution obtained by step (1) carries out once flocculation and subsequent separation supernatant to the filtrate obtained by step (3)
Liquid processing, processing procedure are：Filtrate obtained by step (3) is uniformly heated under conditions of 35-85 DEG C, stirring condition
Lower that adsorptivity flocculation aid is added into filtrate, the addition of adsorptivity flocculation aid is dye gelatin soft capsule shell waste material quality
More than 28%, continue stirring merged completely with filtrate to adsorptivity flocculation aid, then under stirring condition into said mixture not
The disconnected polyacrylamide solution added obtained by step (1), stop addition polyacrylamide solution after flocculation completely and obtain
Flocculated liquid, stands complete to flocculating setting by flocculation liquid, and the supernatant for liquid that finally flocculating setting completely flocculates is separated,
Isolated supernatant is in the clarification liquid of glassy yellow, should be gelatin glue in the supernatant of the clarification liquid of glassy yellow.
Step and time can be saved by only carrying out once flocculation and the processing of subsequent separation supernatant, reduce the thermal degradation of gelatin, more preferably
Protection gelatin quality.
As two kinds of dye gelatin soft capsule shell waste materials of the invention discoloration method it is preferred, polyacrylamide solution
The addition of water described in preparation is to enable to polyacrylamide to be completely dissolved and make the concentration of polyacrylamide solution be
0.1% -0.5%, adsorptivity flocculation aid described in clarifying treatment of flocculating is that high clay or diatomite or perlite or activity are white
Soil.Polyacrylamide solution of low concentration etc. is advantageous to clarifying treatment of subsequently flocculating.The high clay, it is to utilize attapulgite
Clay is by techniques such as immersion, grinding, dehydration, surface active, crushing parcel, allotments through scientific formula and special processing process system
Into a kind of high-viscosity products；The diatomite is a kind of siliceous rock, and its chemical composition is with SiO2Based on, have it is fine and smooth, loose,
Light, porous, water imbibition and the strong physical property of permeability；The perlite is a kind of acidic lava of volcanic eruption, through drastically cold
But the glassy rock formed, perlite ore deposit include perlite, obsidian and pitchstone；The atlapulgite is (main with clay
If bentonite) it is raw material, handled through inorganic acidifying, then rinsed through water, adsorptivity flocculation aid made of drying, its raw material may be used also
Be have clay property ore deposit soil, such as kaolinite clay, montmorillonitic clay, sepiolite clay, Concave-convex clay rod, outward appearance
Odorless for off-white powder, tasteless, nontoxic, absorption property is very strong, can adsorb coloring matter, organic substance, tool high plasticity and
Good caking property is in suspension in aqueous and as a form of gel, also the characteristic with cation exchange.It is high in the present invention viscous
Soil, diatomite, perlite and atlapulgite are powdered as adsorptivity flocculation aid, and in the use of the present invention.
As two kinds of dye gelatin soft capsule shell waste materials of the invention discoloration method it is preferred, after clarifying treatment of flocculating
Also include purification process, purification process process is：The gelatin glue of gained is subjected to cottonseed cake filtering or diatomite filtering or cardboard
Refined filtration, the impurity in gelatin glue is then removed by ion exchange again.Due to the gelatin glue obtained through clarifying treatment of flocculating
Still contain a small amount of impurity, therefore the quality of gelatin can be further improved by purification process.
As two kinds of dye gelatin soft capsule shell waste materials of the invention discoloration method it is preferred, also wrapped after purification process
Gelatin shaping is included, gelatin forming process is：Gelatin glue after purified processing is sterilized, is frozen into again after sterilizing
Type, the gelatin glue of freeze forming is then dried to moisture content less than 14%, finally the gelatin glue of drying is crushed and produced
Gelatin shaped article.Gelatin is done into forming processes, the transport and storage and use of gelatin can be facilitated.
Embodiment
With reference to embodiment, the invention will be further described：
This part carries out general description to the material and test method that are arrived used in present invention experiment.Although it is
Realize that many materials used in the object of the invention and operating method are it is known in the art that still the present invention makees as far as possible herein
It is described in detail.It will be apparent to those skilled in the art that hereinafter, if not specified, material therefor, equipment and operation of the present invention
Method is well known in the art.
Embodiment 1
A kind of discoloration method of dye gelatin soft capsule shell waste material, comprises the following steps：
(1) preparation of polyacrylamide solution
Polyacrylamide is weighed, water is added in polyacrylamide, stirs to polyacrylamide to be completely dissolved and produces poly- third
The acrylamide aqueous solution, concentration that is standby and making polyacrylamide solution are 0.3%；
The addition of the water is to enable to polyacrylamide to be completely dissolved；
(2) preparation of the dye gelatin soft capsule shell waste material aqueous solution
Dye gelatin soft capsule shell waste material is weighed, water is added in dye gelatin soft capsule shell waste material, is stood bright to dyeing
Glue soft capsule shell waste material is expanded completely, and said mixture is then carried out into heating water bath under conditions of 57 DEG C, to dye gelatin
Soft capsule shell waste material, which is completely dissolved, produces the dye gelatin soft capsule shell waste material aqueous solution；
The addition of the water is enables to dye gelatin soft capsule shell waste material to be completely dissolved and makes dye gelatin flexible glue
The concentration of the softgel shell waste material aqueous solution is 5%；
(3) flocculation clarifying treatment
With the polyacrylamide solution obtained by high clay and step (1) to the dye gelatin soft capsule obtained by step (2)
The shell waste material aqueous solution carries out once flocculation and subsequent separation supernatant is handled, and processing procedure is：By the dyeing obtained by step (2)
Soft-gelatin softgel shell rejected water solution carries out heating water bath under conditions of 55 DEG C, to dye gelatin soft capsule shell under stirring condition
High clay is added in the waste material aqueous solution, the addition of high clay is the 65% of dye gelatin soft capsule shell waste material quality, continues to stir
Paramount clay is mixed to merge completely with the dye gelatin soft capsule shell waste material aqueous solution, then under stirring condition into said mixture not
The disconnected polyacrylamide solution added obtained by step (1), stop addition polyacrylamide solution after flocculation completely and obtain
Flocculated liquid, stands complete to flocculating setting by flocculation liquid, and the supernatant for liquid that finally flocculating setting completely flocculates is separated,
Isolated supernatant is in the clarification liquid of glassy yellow, should be gelatin glue in the supernatant of the clarification liquid of glassy yellow；
(4) purification process
Gelatin glue obtained by step (3) is subjected to cottonseed cake filtering, then removed again by ion exchange in gelatin glue
Impurity；
(5) gelatin is molded
The gelatin glue of gained after step (4) purification process is sterilized, carries out freeze forming, freezing temperature after sterilizing again
20 DEG C of degree, it is 5% that the gelatin glue of freeze forming then is dried into moisture content, finally crushes the gelatin glue of drying and produces
Gelatin shaped article.
2-embodiment of embodiment 8
A kind of discoloration method of dye gelatin soft capsule shell waste material, comprises the following steps：
In addition to technological parameter, reagent and reagent content are different, with embodiment 1 the step of embodiment 2 to embodiment 8, by
It is more in embodiment, in order to describe to clearly describe, below with the form of form to the technological parameter in embodiment 2 to embodiment 8,
Reagent and reagent content are stated.Such as table 1：
Table 1：Embodiment 2 is to the step parameter of embodiment 8
Embodiment 9
A kind of discoloration method of dye gelatin soft capsule shell waste material, comprises the following steps：
(1) preparation of polyacrylamide solution
Polyacrylamide is weighed, water is added in polyacrylamide, stirs to polyacrylamide to be completely dissolved and produces poly- third
The acrylamide aqueous solution, concentration that is standby and making polyacrylamide solution are 0.4%；
The addition of the water is to enable to polyacrylamide to be completely dissolved；
(2) preparation of the dye gelatin soft capsule shell waste material aqueous solution
Dye gelatin soft capsule shell waste material is weighed, water is added in dye gelatin soft capsule shell waste material, is stood bright to dyeing
Glue soft capsule shell waste material is expanded completely, and said mixture is then carried out into oil bath heating under conditions of 60 DEG C, to dye gelatin
Soft capsule shell waste material, which is completely dissolved, produces the dye gelatin soft capsule shell waste material aqueous solution；
The addition of the water is enables to dye gelatin soft capsule shell waste material to be completely dissolved and makes dye gelatin flexible glue
The concentration of the softgel shell waste material aqueous solution is 8%；
(3) flocculation clarifying treatment
With the polyacrylamide solution obtained by high clay and step (1) to the dye gelatin soft capsule obtained by step (2)
The shell waste material aqueous solution carries out flocculation twice and subsequent separation supernatant is handled, and processing procedure is：By the dyeing obtained by step (2)
Soft-gelatin softgel shell rejected water solution carries out oil bath heating under conditions of 55 DEG C, to dye gelatin soft capsule shell under stirring condition
High clay is added in the waste material aqueous solution, the addition of high clay is the 40% of dye gelatin soft capsule shell waste material quality, continues to stir
Paramount clay is mixed to merge completely with the dye gelatin soft capsule shell waste material aqueous solution, then under stirring condition into said mixture not
The disconnected polyacrylamide solution added obtained by step (1), stop addition polyacrylamide solution after flocculation completely and obtain
Flocculate liquid, stands complete to flocculating setting by flocculation liquid, the supernatant for liquid that finally flocculating setting completely flocculates is separated
As first separation liquid；First separation liquid is subjected to oil bath heating under conditions of 55 DEG C, to first separation liquid under stirring condition
Middle to add high clay, high clay addition is the 25% of dye gelatin soft capsule shell waste material quality, continue to stir paramount clay with
First separation liquid merges completely, is then continuously added the polyacrylamide obtained by step (1) under stirring condition into said mixture
Amine aqueous solution, until stopping adding the flocculation liquid that polyacrylamide solution obtains first separation liquid after flocculation completely, will once it divide
The flocculation liquid of chaotropic stand it is complete to flocculating setting, finally by the complete first separation liquid of flocculating setting flocculation liquid supernatant
Separate, isolated supernatant is in the clarification liquid of glassy yellow, should be in the supernatant of the clarification liquid of glassy yellow
Gelatin glue；
(4) purification process
Gelatin glue obtained by step (3) is subjected to cottonseed cake filtering, then removed again by ion exchange in gelatin glue
Impurity；
(5) gelatin is molded
The gelatin glue of gained after step (4) purification process is sterilized, carries out freeze forming, freezing temperature after sterilizing again
20 DEG C of degree, it is 14% that the gelatin glue of freeze forming then is dried into moisture content, is by the gelatin glue crushing of drying finally
Obtain gelatin shaped article.
10-embodiment of embodiment 17
A kind of discoloration method of dye gelatin soft capsule shell waste material, comprises the following steps：
In addition to technological parameter, reagent and reagent content are different, with embodiment 9 the step of embodiment 10 to embodiment 17,
Because embodiment is more, in order to describe to clearly describe, below with the form of form to the technique in embodiment 10 to embodiment 17
Parameter, reagent and reagent content are stated.Such as table 2-1：
Table 2-1：Embodiment 10 is to the step parameter of embodiment 17
In addition to technological parameter, reagent and reagent content are different, with embodiment 9 the step of embodiment 18 to embodiment 20,
In order to describe to clearly describe, below with the form of form to technological parameter, reagent and the reagent in embodiment 18 to embodiment 20
Content is stated.Such as table 2-2：
Table 2-2：Embodiment 18 is to the step parameter of embodiment 20
Embodiment 21
A kind of discoloration method of dye gelatin soft capsule shell waste material, comprises the following steps：
(1) preparation of polyacrylamide solution
Polyacrylamide is weighed, water is added in polyacrylamide, stirs to polyacrylamide to be completely dissolved and produces poly- third
The acrylamide aqueous solution, concentration that is standby and making polyacrylamide solution are 0.3%；
The addition of the water is to enable to polyacrylamide to be completely dissolved；
(2) preparation of the dye gelatin soft capsule shell waste material aqueous solution
Dye gelatin soft capsule shell waste material is weighed, water is added in dye gelatin soft capsule shell waste material, is stood bright to dyeing
Glue soft capsule shell waste material is expanded completely, and said mixture is then carried out into heating water bath under conditions of 57 DEG C, to dye gelatin
Soft capsule shell waste material, which is completely dissolved, produces the dye gelatin soft capsule shell waste material aqueous solution；
The addition of the water is enables to dye gelatin soft capsule shell waste material to be completely dissolved and makes dye gelatin flexible glue
The concentration of the softgel shell waste material aqueous solution is 5%；
(3) activated carbon decolorizing filtration treatment
Activated carbon decolorizing and subsequent mistake are carried out to the dye gelatin soft capsule shell waste material aqueous solution obtained by step (3)
Filter is handled, and processing procedure is：Activated carbon is added into the dye gelatin soft capsule shell waste material aqueous solution under stirring condition, activated carbon
Addition is the 30% of dye gelatin soft capsule shell waste material quality, continues to stir 30min, makes activated carbon and dye gelatin soft capsule
The shell waste material aqueous solution merges completely, is then filtered said mixture, and the filtrate obtained after filtering is in the red muddiness of skin
Liquid；
(4) flocculation clarifying treatment
The filtrate obtained by step (3) is once wadded a quilt with cotton with the polyacrylamide solution obtained by high clay and step (1)
Solidifying and subsequent separation supernatant is handled, and processing procedure is：Filtrate obtained by step (3) is subjected to water-bath under conditions of 55 DEG C
Heat, add high clay under stirring condition into filtrate, the addition of high clay is dye gelatin soft capsule shell waste material quality
55%, continue to stir paramount clay and merged completely with filtrate, step is then continuously added into said mixture under stirring condition
(1) polyacrylamide solution obtained by, until stopping adding polyacrylamide solution after flocculation completely must flocculate liquid, will wad a quilt with cotton
Lime set stands complete to flocculating setting, and the supernatant for liquid that finally flocculating setting completely flocculates is separated, isolated
Supernatant is in the clarification liquid of glassy yellow, should be gelatin glue in the supernatant of the clarification liquid of glassy yellow；
(5) purification process
Gelatin glue obtained by step (4) is subjected to cottonseed cake filtering, then removed again by ion exchange in gelatin glue
Impurity；
(6) gelatin is molded
The gelatin glue of gained after step (5) purification process is sterilized, carries out freeze forming, freezing temperature after sterilizing again
20 DEG C of degree, it is 11% that the gelatin glue of freeze forming then is dried into moisture content, is by the gelatin glue crushing of drying finally
Obtain gelatin shaped article.
22-embodiment of embodiment 28
A kind of discoloration method of dye gelatin soft capsule shell waste material, comprises the following steps：
In addition to technological parameter, reagent and reagent content are different, with embodiment 21 the step of embodiment 22 to embodiment 28,
Because embodiment is more, in order to describe to clearly describe, below with the form of form to the technique in embodiment 22 to embodiment 28
Parameter, reagent and reagent content are stated.Such as table 3：
Table 3：Embodiment 22 is to the step parameter of embodiment 28
Embodiment 29
A kind of discoloration method of dye gelatin soft capsule shell waste material, comprises the following steps：
(1) preparation of polyacrylamide solution
Polyacrylamide is weighed, water is added in polyacrylamide, stirs to polyacrylamide to be completely dissolved and produces poly- third
The acrylamide aqueous solution, concentration that is standby and making polyacrylamide solution are 0.5%；
The addition of the water is to enable to polyacrylamide to be completely dissolved；
(2) preparation of the dye gelatin soft capsule shell waste material aqueous solution
Dye gelatin soft capsule shell waste material is weighed, water is added in dye gelatin soft capsule shell waste material, is stood bright to dyeing
Glue soft capsule shell waste material expands completely, said mixture is then carried out into coil pipe heating under conditions of 55 DEG C, to dye gelatin
Soft capsule shell waste material, which is completely dissolved, produces the dye gelatin soft capsule shell waste material aqueous solution；
The addition of the water is enables to dye gelatin soft capsule shell waste material to be completely dissolved and makes dye gelatin flexible glue
The concentration of the softgel shell waste material aqueous solution is 1%；
(3) activated carbon decolorizing filtration treatment
Activated carbon decolorizing and subsequent mistake twice are carried out to the dye gelatin soft capsule shell waste material aqueous solution obtained by step (2)
Filter is handled, and processing procedure is：Activated carbon is added into the dye gelatin soft capsule shell waste material aqueous solution under stirring condition, activated carbon
Addition is the 20% of dye gelatin soft capsule shell waste material quality, continues to stir 40min, makes activated carbon and dye gelatin soft capsule
The shell waste material aqueous solution merges completely, then carries out said mixture to filter to obtain first-time filtrate；To first-time filtrate under stirring condition
Middle addition activated carbon, the addition of activated carbon are the 2% of dye gelatin soft capsule shell waste material quality, continue to stir 30min, make work
Property charcoal merged completely with first-time filtrate, then said mixture is filtered, the filtrate obtained after filtering is in red muddy of skin
Turbid shape；
(4) flocculation clarifying treatment
The filtrate obtained by step (3) is once wadded a quilt with cotton with the polyacrylamide solution obtained by high clay and step (1)
Solidifying and subsequent separation supernatant is handled, and processing procedure is：Filtrate obtained by step (3) is subjected to coil pipe under conditions of 75 DEG C
Heat, add high clay under stirring condition into filtrate, the addition of high clay is dye gelatin soft capsule shell waste material quality
55%, continue to stir paramount clay and merged completely with filtrate, step is then continuously added into said mixture under stirring condition
(1) polyacrylamide solution obtained by, until stopping adding polyacrylamide solution after flocculation completely must flocculate liquid, will wad a quilt with cotton
Lime set stands complete to flocculating setting, and the supernatant for liquid that finally flocculating setting completely flocculates is separated, isolated
Supernatant is in the clarification liquid of glassy yellow, should be gelatin glue in the supernatant of the clarification liquid of glassy yellow；
(5) purification process
Gelatin glue obtained by step (4) is subjected to cardboard refined filtration, then removed again by ion exchange in gelatin glue
Impurity；
(6) gelatin is molded
The gelatin glue of gained after step (5) purification process is sterilized, carries out freeze forming, freezing temperature after sterilizing again
15 DEG C of degree, it is 9% that the gelatin glue of freeze forming then is dried into moisture content, finally crushes the gelatin glue of drying and produces
Gelatin shaped article.
It should be understood that example as described herein and embodiment can be made only for explanation, those skilled in the art according to it
Various modifications or change, belong to protection scope of the present invention.
Embodiment 30
A kind of discoloration method of dye gelatin soft capsule shell waste material, comprises the following steps：
(1) preparation of polyacrylamide solution
Polyacrylamide is weighed, water is added in polyacrylamide, stirs to polyacrylamide to be completely dissolved and produces poly- third
The acrylamide aqueous solution, concentration that is standby and making polyacrylamide solution are 0.2%；
The addition of the water is to enable to polyacrylamide to be completely dissolved；
(2) preparation of the dye gelatin soft capsule shell waste material aqueous solution
Dye gelatin soft capsule shell waste material is weighed, water is added in dye gelatin soft capsule shell waste material, is stood bright to dyeing
Glue soft capsule shell waste material expands completely, said mixture is then carried out into coil pipe heating under conditions of 60 DEG C, to dye gelatin
Soft capsule shell waste material, which is completely dissolved, produces the dye gelatin soft capsule shell waste material aqueous solution；
The addition of the water is enables to dye gelatin soft capsule shell waste material to be completely dissolved and makes dye gelatin flexible glue
The concentration of the softgel shell waste material aqueous solution is 5%；
(3) activated carbon decolorizing filtration treatment
Activated carbon decolorizing and subsequent mistake twice are carried out to the dye gelatin soft capsule shell waste material aqueous solution obtained by step (2)
Filter is handled, and processing procedure is：Activated carbon is added into the dye gelatin soft capsule shell waste material aqueous solution under stirring condition, activated carbon
Addition is the 30% of dye gelatin soft capsule shell waste material quality, continues to stir 30min, makes activated carbon and dye gelatin soft capsule
The shell waste material aqueous solution merges completely, then carries out said mixture to filter to obtain first-time filtrate；To first-time filtrate under stirring condition
Middle addition activated carbon, the addition of activated carbon are the 30% of dye gelatin soft capsule shell waste material quality, continue to stir 40min, make
Activated carbon merges completely with first-time filtrate, is then filtered said mixture, and the filtrate obtained after filtering is in skin red
Muddy liquid；
(4) flocculation clarifying treatment
The filtrate obtained by step (3) is once wadded a quilt with cotton with the polyacrylamide solution obtained by diatomite and step (1)
Solidifying and subsequent separation supernatant is handled, and processing procedure is：Filtrate obtained by step (3) is subjected to coil pipe under conditions of 75 DEG C
Heat, add diatomite under stirring condition into filtrate, diatomaceous addition is dye gelatin soft capsule shell waste material quality
60%, continue stirring and merged completely with filtrate to diatomite, step is then continuously added into said mixture under stirring condition
(1) polyacrylamide solution obtained by, until stopping adding polyacrylamide solution after flocculation completely must flocculate liquid, will wad a quilt with cotton
Lime set stands complete to flocculating setting, and the supernatant for liquid that finally flocculating setting completely flocculates is separated, isolated
Supernatant is in the clarification liquid of glassy yellow, should be gelatin glue in the supernatant of the clarification liquid of glassy yellow；
(5) purification process
Gelatin glue obtained by step (4) is subjected to cottonseed cake filtering, then removed again by ion exchange in gelatin glue
Impurity；
(6) gelatin is molded
The gelatin glue of gained after step (5) purification process is sterilized, carries out freeze forming, freezing temperature after sterilizing again
10 DEG C of degree, it is 11% that the gelatin glue of freeze forming then is dried into moisture content, is by the gelatin glue crushing of drying finally
Obtain gelatin shaped article.
Embodiment 31
A kind of discoloration method of dye gelatin soft capsule shell waste material, comprises the following steps：
(1) preparation of polyacrylamide solution
Polyacrylamide is weighed, water is added in polyacrylamide, stirs to polyacrylamide to be completely dissolved and produces poly- third
The acrylamide aqueous solution, concentration that is standby and making polyacrylamide solution are 0.4%；
The addition of the water is to enable to polyacrylamide to be completely dissolved；
(2) preparation of the dye gelatin soft capsule shell waste material aqueous solution
Dye gelatin soft capsule shell waste material is weighed, water is added in dye gelatin soft capsule shell waste material, is stood bright to dyeing
Glue soft capsule shell waste material is expanded completely, and said mixture is then carried out into heating water bath under conditions of 60 DEG C, to dye gelatin
Soft capsule shell waste material, which is completely dissolved, produces the dye gelatin soft capsule shell waste material aqueous solution；
The addition of the water is enables to dye gelatin soft capsule shell waste material to be completely dissolved and makes dye gelatin flexible glue
The concentration of the softgel shell waste material aqueous solution is 15%；
(3) activated carbon decolorizing filtration treatment
Activated carbon decolorizing and subsequent mistake twice are carried out to the dye gelatin soft capsule shell waste material aqueous solution obtained by step (2)
Filter is handled, and processing procedure is：Activated carbon is added into the dye gelatin soft capsule shell waste material aqueous solution under stirring condition, activated carbon
Addition is the 40% of dye gelatin soft capsule shell waste material quality, continues to stir 45min, makes activated carbon and dye gelatin soft capsule
The shell waste material aqueous solution merges completely, then carries out said mixture to filter to obtain first-time filtrate；To first-time filtrate under stirring condition
Middle addition activated carbon, the addition of activated carbon are the 15% of dye gelatin soft capsule shell waste material quality, continue to stir 40min, make
Activated carbon merges completely with first-time filtrate, is then filtered said mixture, and the filtrate obtained after filtering is in skin red
Muddy liquid；
(4) flocculation clarifying treatment
The filtrate obtained by step (3) is once wadded a quilt with cotton with the polyacrylamide solution obtained by perlite and step (1)
Solidifying and subsequent separation supernatant is handled, and processing procedure is：Filtrate obtained by step (3) is subjected to water-bath under conditions of 75 DEG C
Heat, add perlite under stirring condition into filtrate, the addition of perlite is dye gelatin soft capsule shell waste material quality
57%, continue stirring and merged completely with filtrate to perlite, step is then continuously added into said mixture under stirring condition
(1) polyacrylamide solution obtained by, until stopping adding polyacrylamide solution after flocculation completely must flocculate liquid, will wad a quilt with cotton
Lime set stands complete to flocculating setting, and the supernatant for liquid that finally flocculating setting completely flocculates is separated, isolated
Supernatant is in the clarification liquid of glassy yellow, should be gelatin glue in the supernatant of the clarification liquid of glassy yellow；
(5) purification process
Gelatin glue obtained by step (4) is subjected to cottonseed cake filtering, then removed again by ion exchange in gelatin glue
Impurity；
(6) gelatin is molded
The gelatin glue of gained after step (5) purification process is sterilized, carries out freeze forming, freezing temperature after sterilizing again
7 DEG C of degree, it is 6% that the gelatin glue of freeze forming then is dried into moisture content, finally crushes the gelatin glue of drying and produces
Gelatin shaped article.
Embodiment 32
A kind of discoloration method of dye gelatin soft capsule shell waste material, comprises the following steps：
(1) preparation of polyacrylamide solution
Polyacrylamide is weighed, water is added in polyacrylamide, stirs to polyacrylamide to be completely dissolved and produces poly- third
The acrylamide aqueous solution, concentration that is standby and making polyacrylamide solution are 0.3%；
The addition of the water is to enable to polyacrylamide to be completely dissolved；
(2) preparation of the dye gelatin soft capsule shell waste material aqueous solution
Dye gelatin soft capsule shell waste material is weighed, water is added in dye gelatin soft capsule shell waste material, is stood bright to dyeing
Glue soft capsule shell waste material is expanded completely, and said mixture is then carried out into heating water bath under conditions of 63 DEG C, to dye gelatin
Soft capsule shell waste material, which is completely dissolved, produces the dye gelatin soft capsule shell waste material aqueous solution；
The addition of the water is enables to dye gelatin soft capsule shell waste material to be completely dissolved and makes dye gelatin flexible glue
The concentration of the softgel shell waste material aqueous solution is 10%；
(3) activated carbon decolorizing filtration treatment
Activated carbon decolorizing and subsequent mistake twice are carried out to the dye gelatin soft capsule shell waste material aqueous solution obtained by step (2)
Filter is handled, and processing procedure is：Activated carbon is added into the dye gelatin soft capsule shell waste material aqueous solution under stirring condition, activated carbon
Addition is the 25% of dye gelatin soft capsule shell waste material quality, continues to stir 45min, makes activated carbon and dye gelatin soft capsule
The shell waste material aqueous solution merges completely, then carries out said mixture to filter to obtain first-time filtrate；To first-time filtrate under stirring condition
Middle addition activated carbon, the addition of activated carbon are the 20% of dye gelatin soft capsule shell waste material quality, continue to stir 40min, make
Activated carbon merges completely with first-time filtrate, is then filtered said mixture, and the filtrate obtained after filtering is in skin red
Muddy liquid；
(4) flocculation clarifying treatment
The filtrate obtained by step (3) is carried out once with the polyacrylamide solution obtained by atlapulgite and step (1)
Flocculation and subsequent separation supernatant are handled, and processing procedure is：Filtrate obtained by step (3) is entered into water-filling under conditions of 75 DEG C
Bath is heated, and atlapulgite is added into filtrate under stirring condition, the addition of atlapulgite is dye gelatin soft capsule shell waste material
The 60% of quality, continue to stir paramount clay and merged completely with filtrate, then under stirring condition into said mixture constantly plus
Enter the polyacrylamide solution obtained by step (1), until the completely rear stopping of flocculation adds polyacrylamide solution and must flocculated
Liquid, flocculation liquid is stood complete to flocculating setting, the supernatant for liquid that finally flocculating setting completely flocculates is separated, separation
Obtained supernatant is in the clarification liquid of glassy yellow, should be gelatin glue in the supernatant of the clarification liquid of glassy yellow；
(5) purification process
Gelatin glue obtained by step (4) is subjected to diatomite filtering, gelatin glue is then removed by ion exchange again
In impurity；
(6) gelatin is molded
The gelatin glue of gained after step (5) purification process is sterilized, carries out freeze forming, freezing temperature after sterilizing again
7 DEG C of degree, it is 6% that the gelatin glue of freeze forming then is dried into moisture content, finally crushes the gelatin glue of drying and produces
Gelatin shaped article.
High clay, diatomite, perlite and atlapulgite are powdered in above-mentioned all embodiments；The step of needing stirring
In, its mixing speed is 200r/min -300r/min.
In concrete practice, for different dye gelatin hard capsule case waste materials, heavier, activated carbon and adsorptivity are dyed
The dosage of flocculation aid can increase, and this is foreseeable for a person skilled in the art.
It should be understood that example as described herein and embodiment can be made only for explanation, those skilled in the art according to it
Various modifications or change, in the case where not departing from spirit of the invention, belong to protection scope of the present invention.
Claims (10)
1. a kind of discoloration method of dye gelatin soft capsule shell waste material, comprises the following steps：
（1）The preparation of polyacrylamide solution
Polyacrylamide is weighed, water is added in polyacrylamide, stirs to polyacrylamide to be completely dissolved and produces polyacrylamide
Amine aqueous solution, it is standby；
The addition of the water is to enable to polyacrylamide to be completely dissolved；
（2）The preparation of the dye gelatin soft capsule shell waste material aqueous solution
Dye gelatin soft capsule shell waste material is weighed, water is added in dye gelatin soft capsule shell waste material, is stood soft to dye gelatin
Capsule shells waste material expands completely, then by the mixture of above-mentioned water and the dye gelatin soft capsule shell waste material expanded completely 35-
Uniformly heated under conditions of 85 DEG C, be completely dissolved to dye gelatin soft capsule shell waste material and produce dye gelatin soft capsule shell and give up
Expect the aqueous solution；
The addition of the water is enables to dye gelatin soft capsule shell waste material to be completely dissolved and makes dye gelatin soft capsule shell
The concentration of the waste material aqueous solution is 1% -25%；
（3）Flocculation clarifying treatment
With adsorptivity flocculation aid and step（1）The polyacrylamide solution of gained is to step（2）The dye gelatin flexible glue of gained
The softgel shell waste material aqueous solution carries out the flocculation and the processing of subsequent separation supernatant more than once or twice, until isolated is upper
Clear liquid is in the clarification liquid of glassy yellow, should be gelatin glue in the supernatant of the clarification liquid of glassy yellow.
2. a kind of discoloration method of dye gelatin soft capsule shell waste material, comprises the following steps：
（1）The preparation of polyacrylamide solution
Polyacrylamide is weighed, water is added in polyacrylamide, stirs to polyacrylamide to be completely dissolved and produces polyacrylamide
Amine aqueous solution, it is standby；
The addition of the water is to enable to polyacrylamide to be completely dissolved；
（2）The preparation of the dye gelatin soft capsule shell waste material aqueous solution
Dye gelatin soft capsule shell waste material is weighed, water is added in dye gelatin soft capsule shell waste material, is stood soft to dye gelatin
Capsule shells waste material expands completely, then by the mixture of above-mentioned water and the dye gelatin soft capsule shell waste material expanded completely 35-
Uniformly heated under conditions of 85 DEG C, be completely dissolved to dye gelatin soft capsule shell waste material and produce dye gelatin soft capsule shell and give up
Expect the aqueous solution；
The addition of the water is enables to dye gelatin soft capsule shell waste material to be completely dissolved and makes dye gelatin soft capsule shell
The concentration of the waste material aqueous solution is 1% -25%；
（3）Activated carbon decolorizing filtration treatment
To step（2）The dye gelatin hard capsule case waste material aqueous solution of gained carry out above activated carbon decolorizing once or twice and with
Filtration treatment afterwards, until the filtrate obtained after filtering is in the red muddy liquid of skin；
（4）Flocculation clarifying treatment
With adsorptivity flocculation aid and step（1）The polyacrylamide solution of gained is to step（3）The filtrate of gained is carried out once
Or flocculation and the processing of subsequent separation supernatant more than twice, until isolated supernatant is in the clarified solution of glassy yellow
Shape, should be gelatin glue in the supernatant of the clarification liquid of glassy yellow.
3. the discoloration method of dye gelatin soft capsule shell waste material as claimed in claim 1, it is characterised in that：Helped with adsorptivity solidifying
Agent and step（1）The polyacrylamide solution of gained is to step（2）The dye gelatin soft capsule shell waste material aqueous solution of gained enters
Once flocculation and subsequent separation supernatant are handled row, and processing procedure is：By step（2）The dye gelatin soft capsule shell of gained gives up
The material aqueous solution is uniformly heated under conditions of 35-85 DEG C, to the dye gelatin soft capsule shell waste material aqueous solution under stirring condition
Middle addition adsorptivity flocculation aid, the addition of adsorptivity flocculation aid are more than the 65% of dye gelatin soft capsule shell waste material quality, after
Continuous stirring is merged completely to adsorptivity flocculation aid with the dye gelatin soft capsule shell waste material aqueous solution, then to above-mentioned under stirring condition
Step is continuously added in mixture（1）The polyacrylamide solution of gained, until stopping adding polyacrylamide after flocculation completely
Amine aqueous solution must be flocculated liquid, and flocculation liquid is stood into, the supernatant of finally flocculating setting completely flocculates liquid complete to flocculating setting
Liquid is separated, and isolated supernatant is in the clarification liquid of glassy yellow, should be in the supernatant of the clarification liquid of glassy yellow
For gelatin glue.
4. the discoloration method of dye gelatin soft capsule shell waste material as claimed in claim 1, it is characterised in that：Helped with adsorptivity solidifying
Agent and step（1）The polyacrylamide solution of gained is to step（2）The dye gelatin soft capsule shell waste material aqueous solution of gained enters
Row flocculation twice and subsequent separation supernatant are handled, and processing procedure is：By step（2）The dye gelatin soft capsule shell of gained gives up
The material aqueous solution is uniformly heated under conditions of 35-85 DEG C, to the dye gelatin soft capsule shell waste material aqueous solution under stirring condition
Middle addition adsorptivity flocculation aid, the addition of adsorptivity flocculation aid are 40%-the 55% of dye gelatin soft capsule shell waste material quality,
Continue stirring to merge completely with the dye gelatin soft capsule shell waste material aqueous solution to adsorptivity flocculation aid, then under stirring condition upwards
State and step is continuously added in mixture（1）The polyacrylamide solution of gained, until stopping adding polypropylene after flocculation completely
Amide aqueous solution must be flocculated liquid, and flocculation liquid is stood into, finally flocculating setting completely flocculates liquid upper complete to flocculating setting
Clear liquid is separated as first separation liquid；First separation liquid is uniformly heated under conditions of 35-85 DEG C, stirring bar
Adsorptivity flocculation aid is added under part into first separation liquid, the addition of adsorptivity flocculation aid is dye gelatin soft capsule shell waste material
25%-the 30% of quality, continue stirring and merged completely with first separation liquid to adsorptivity flocculation aid, then under stirring condition upwards
State and step is continuously added in mixture（1）The polyacrylamide solution of gained, until stopping adding polypropylene after flocculation completely
Amide aqueous solution obtains the flocculation liquid of first separation liquid, the flocculation liquid of first separation liquid is stood it is complete to flocculating setting, finally will
The supernatant of the flocculation liquid of the complete first separation liquid of flocculating setting is separated, and isolated supernatant is clear in glassy yellow
Clear liquid shape, should be gelatin glue in the supernatant of the clarification liquid of glassy yellow.
5. the discoloration method of dye gelatin soft capsule shell waste material as claimed in claim 2, it is characterised in that：To step（2）Institute
The dye gelatin soft capsule shell waste material aqueous solution obtained carries out an activated carbon decolorizing and subsequent filtration treatment, processing procedure are：
Activated carbon is added under stirring condition into the dye gelatin soft capsule shell waste material aqueous solution, the addition of activated carbon is soft for dye gelatin
More than the 30% of capsule shells waste material quality, continue to stir more than 30min, make activated carbon and dye gelatin soft capsule shell waste material water-soluble
Liquid merges completely, is then filtered said mixture, and the filtrate obtained after filtering is in the red muddy liquid of skin.
6. the discoloration method of dye gelatin soft capsule shell waste material as claimed in claim 2, it is characterised in that：To step（2）Institute
Activated carbon decolorizing and subsequent filtration treatment, processing procedure are twice for the dye gelatin soft capsule shell waste material aqueous solution progress obtained：
Activated carbon is added under stirring condition into the dye gelatin soft capsule shell waste material aqueous solution, the addition of activated carbon is soft for dye gelatin
20%-the 40% of capsule shells waste material quality, continue to stir more than 30min, make activated carbon and dye gelatin soft capsule shell waste material water-soluble
Liquid merges completely, then carries out said mixture to filter to obtain first-time filtrate；Activity is added under stirring condition into first-time filtrate
Charcoal, the addition of activated carbon are 1%-the 30% of dye gelatin soft capsule shell waste material quality, continue to stir more than 30min, make activity
Charcoal merges completely with first-time filtrate, is then filtered said mixture, and the filtrate obtained after filtering is in the red muddiness of skin
Liquid.
7. the discoloration method of the dye gelatin soft capsule shell waste material as described in claim 2 or 5 or 6, it is characterised in that：With absorption
Property flocculation aid and step（1）The polyacrylamide solution of gained is to step（3）The filtrate of gained carries out once flocculation and then
The processing of separation supernatant, processing procedure is：By step（3）The filtrate of gained carries out uniformly adding under conditions of 35-85 DEG C
Heat, adsorptivity flocculation aid is added under stirring condition into filtrate, the addition of adsorptivity flocculation aid is dye gelatin soft capsule shell
More than the 55% of waste material quality, continue stirring and merged completely with filtrate to adsorptivity flocculation aid, then to above-mentioned mixed under stirring condition
Step is continuously added in compound（1）The polyacrylamide solution of gained, until stopping adding polyacrylamide after flocculation completely
The aqueous solution must be flocculated liquid, and flocculation liquid is stood into, the supernatant of finally flocculating setting completely flocculates liquid complete to flocculating setting
Separate, isolated supernatant is in the clarification liquid of glassy yellow, should be in the supernatant of the clarification liquid of glassy yellow
Gelatin glue.
8. the discoloration method of the dye gelatin soft capsule shell waste material as any one of claim 1 to 6, it is characterised in that：
The addition of water described in the preparation of polyacrylamide solution is enables to polyacrylamide to be completely dissolved and makes polypropylene
The concentration of amide aqueous solution is 0.1% -0.5%, adsorptivity flocculation aid described in clarifying treatment of flocculating be high clay or diatomite or
Perlite or atlapulgite.
9. the discoloration method of the dye gelatin soft capsule shell waste material as any one of claim 1 to 6, it is characterised in that：
Also include purification process after clarifying treatment of flocculating, purification process process is：The gelatin glue of gained is subjected to cottonseed cake filtering
Or diatomite filtering or cardboard refined filtration, the impurity in gelatin glue is then removed by ion exchange again.
10. the discoloration method of dye gelatin soft capsule shell waste material as claimed in claim 9, it is characterised in that：In purification process
Also include gelatin afterwards to be molded, gelatin forming process is：Gelatin glue after purified processing is sterilized, entered again after sterilizing
Row freeze forming, the gelatin glue of freeze forming is then dried to moisture content less than 14%, finally by the gelatin glue powder of drying
It is broken to produce gelatin shaped article.
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