CN104510792A - Medicine for treating osteoarticular diseases and preparation method thereof - Google Patents

Medicine for treating osteoarticular diseases and preparation method thereof Download PDF

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Publication number
CN104510792A
CN104510792A CN201310457737.1A CN201310457737A CN104510792A CN 104510792 A CN104510792 A CN 104510792A CN 201310457737 A CN201310457737 A CN 201310457737A CN 104510792 A CN104510792 A CN 104510792A
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parts
radix
medicine
rhizoma
joint disease
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刘常春
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A61K36/12—Filicopsida or Pteridopsida
    • A61K36/126—Drynaria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/237—Notopterygium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238—Saposhnikovia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/254—Acanthopanax or Eleutherococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286—Carthamus (distaff thistle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/324—Boswellia, e.g. frankincense
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/51—Gentianaceae (Gentian family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/716—Clematis (leather flower)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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  • Health & Medical Sciences (AREA)
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Abstract

The invention relates to a medicine for treating osteoarticular diseases and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines. The medicine for treating osteoarticular diseases is special in comprising the following raw materials, by weight, 20-50 parts of cortex acanthopanacis, 20-50 parts of safflower, 20-50 parts of Ligusticum wallichii, 10-30 parts of clematis root, 10-30 parts of rhizoma drynariae, 10-30 parts of divaricate saposhnikovia root, 10-30 parts of frankincense, 10-20 parts of bark of ash, 10-20 parts of achyranthes root, 10-20 parts of levisticum and 10-20 parts of notopterygium root. The preparation method comprises the following steps: 1) material preparation; 2) immersion; and 3) decoction. The formula provided by the invention gives prominence to key points, is scientific in compatibility of medicines and is comprehensive and reasonable. The medicine provided by the invention can effectively treat osteoarticular diseases such as proliferative osteoarthritis, degenerative joint disease, senescent arthritis, hypertrophic arthritis and the like, has short treatment course, has fast effectiveness and has no toxic or side effect. Effective rate of the medicine can reach 95%.

Description

A kind of medicine for the treatment of joint disease and preparation method thereof
Technical field
The present invention relates to a kind of medicine for the treatment of joint disease and preparation method thereof, belong to technical field of Chinese medicine.
Background technology
Joint disease comprises hyperplastic osteoarthritis, degenerative joint disease, senile arthritis, hypertrophiarthritis, osteoarthritis.Its pathogeny is that degeneration, degeneration appear in the soft tissue such as cartilage, intervertebral disc, ligament forming joint, and joint margins forms bony spur or occurs the changes such as synovial membrane thickens, thus osteoclasia occurs, and causes insecondary hyperosteogeny and causes joint deformity.Joint disease is comparatively common, clinical manifestation be swollen joint, bitterly, hydrops, stiff, hypertrophy, bony spur, patient activity is limited, agonizing, being permitted all Drug therapys is generally relief of symptoms, is difficult to cure, and very easily repeatedly, serious threat the quality of life of people with healthy.
Summary of the invention
The object of the invention is to the deficiency solving the existence of above-mentioned prior art, medicine of a kind of effective treatment joint disease and preparation method thereof is provided
The present invention is achieved through the following technical solutions:
Treat a medicine for joint disease, its special character is to be made up of the raw material of following weight portion:
Cortex Acanthopancis 20-50 part, Flos Carthami 20-50 part, Rhizoma Chuanxiong 20-50 part, Radix Clematidis 10-30 part, Rhizoma Drynariae 10-30 part, Radix Saposhnikoviae 10-30 part, Olibanum 10-30 part, Radix Gentianae Macrophyllae 10-20 part, Radix Achyranthis Bidentatae 10-20 part, Radix Angelicae Pubescentis 10-20 part, Rhizoma Et Radix Notopterygii 10-20 part.
The medicine of described treatment joint disease, is made up of the raw material of following weight portion:
Cortex Acanthopancis 30-40 part, Flos Carthami 30-40 part, Rhizoma Chuanxiong 30-40 part, Radix Clematidis 20-30 part, Rhizoma Drynariae 20-30 part, Radix Saposhnikoviae 20-30 part, Olibanum 20-30 part, Radix Gentianae Macrophyllae 20-20 part, Radix Achyranthis Bidentatae 10-20 part, Radix Angelicae Pubescentis 10-20 part, Rhizoma Et Radix Notopterygii 10-20 part.
The medicine of described treatment joint disease, the raw material composition of preferred following weight portion:
Cortex Acanthopancis 40 parts, 40 parts, Flos Carthami, Rhizoma Chuanxiong 40 parts, Radix Clematidis 25 parts, Rhizoma Drynariae 25 parts, Radix Saposhnikoviae 25 parts, Olibanum 25 parts, Radix Gentianae Macrophyllae 15 parts, Radix Achyranthis Bidentatae 15 parts, Radix Angelicae Pubescentis 15 parts, Rhizoma Et Radix Notopterygii 15 parts.The preparation method of the medicine of above-mentioned treatment joint disease, its special character is to comprise the following steps:
1, get the raw materials ready: take various raw material according to weight portion needed for each tcm components.
2, soak: the various raw materials taken by weight are put into ceramic medicinal cupping, add pure water and soak, 20 ~ 40 minutes time, amount of water requires to cover powder.
3, boil medicine: after intense fire is boiled, 20-40 minute at a simmer, filters out medicine juice; In medicinal cupping, add boiled water again, after intense fire is boiled, 15-25 minute at a simmer, leaches medicine juice again, by twice gained medicine juice mix homogeneously.
Drug administration method of the present invention: every day 1 dose, sooner or later taking, 10 days is 1 course for the treatment of.
Period in a medicine is avoided: treatment, period in a medicine taboo edible fried glutinous greasy, solid hard cold, food nondigestible and excitatory.
The present invention treats the Main Function of various raw material in joint disease medicine:
[Cortex Acanthopancis] is pungent, bitter, temperature.Return liver, kidney channel.Eradicates rheumatism, invigorating the liver and kidney, bone and muscle strengthening, diuretic.
[Flos Carthami] acrid in the mouth, warm in nature, GUIXIN, Liver Channel.There is promoting blood circulation to restore menstrual flow, effect of stasis-dispelling and pain-killing.
[Rhizoma Chuanxiong] is pungent loose, and Wen Tong, invigorates blood circulation, blood stasis dispelling.
[Radix Clematidis] is pungent, salty, temperature.Return urinary bladder channel.Wind-damp dispelling, removing obstruction in the collateral to relieve pain, disappear a fishbone or other bone caught in the throat.
[Rhizoma Drynariae] is warm in nature, bitter in the mouth.The kidney invigorating bone strengthening, continuous muscle of invigorating blood circulation, invigorates blood circulation, hemostasis.
[Radix Saposhnikoviae] is pungent, sweet, tepor.Return lung, bladder, liver, spleen channel.Expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion.
[Olibanum] property acrid, bitter, warm.Enter the heart, liver, spleen channel.Invigorate blood circulation, circulation of qi promoting, pain relieving.
[Radix Gentianae Macrophyllae] is pungent, bitter, flat.Return stomach, liver, gallbladder meridian; Eradicates rheumatism, removing obstruction in the collateral to relieve pain, reducing the asthenic fever, clearing away damp-heat.
[Radix Achyranthis Bidentatae] is bitter, acid, and property is put down.Invigorating the liver and kidney, bone and muscle strengthening, promoting blood circulation to restore menstrual flow, ignite (blood) is descending, inducing diuresis for treating stranguria syndrome.
[Radix Angelicae Pubescentis] bitter in the mouth, sweet, flat. nontoxic, enter small intestinal. bladder. liver. kidney four warp.Wind-damp dispelling, stopping numbness pain.
[Rhizoma Et Radix Notopterygii] is pungent, bitter, temperature.Induce sweat cold expelling, expelling wind and dampness, pain relieving.
Formula of the present invention, gives prominence to the key points, compatibility science, comprehensive and reasonable.Can effectively treat the joint disease such as hyperplastic osteoarthritis, degenerative joint disease, senile arthritis, hypertrophiarthritis, short treating period, instant effect, has no side effect, and effective percentage can reach 95%.
Detailed description of the invention
Below provide the specific embodiment of the present invention, be used for being further described formation of the present invention.
Embodiment 1
The treatment joint disease medicine of the present embodiment, comprises the raw material of following weight portion:
Cortex Acanthopancis 40 parts, 40 parts, Flos Carthami, Rhizoma Chuanxiong 40 parts, Radix Clematidis 25 parts, Rhizoma Drynariae 25 parts, Radix Saposhnikoviae 25 parts, Olibanum 25 parts, Radix Gentianae Macrophyllae 15 parts, Radix Achyranthis Bidentatae 15 parts, Radix Angelicae Pubescentis 15 parts, Rhizoma Et Radix Notopterygii 15 parts.
Embodiment 2
The treatment joint disease medicine of the present embodiment, comprises the raw material of following weight portion:
Cortex Acanthopancis 50 parts, 50 parts, Flos Carthami, Rhizoma Chuanxiong 50 parts, Radix Clematidis 130 parts, Rhizoma Drynariae 30 parts, Radix Saposhnikoviae 30 parts, Olibanum 30 parts, Radix Gentianae Macrophyllae 20 parts, Radix Achyranthis Bidentatae 20 parts, Radix Angelicae Pubescentis 20 parts, Rhizoma Et Radix Notopterygii 20 parts.
Embodiment 3
The treatment joint disease medicine of the present embodiment, comprises the raw material of following weight portion:
Cortex Acanthopancis 20 parts, 20 parts, Flos Carthami, Rhizoma Chuanxiong 20 parts, Radix Clematidis 10 parts, Rhizoma Drynariae 10 parts, Radix Saposhnikoviae 10 parts, Olibanum 10 parts, Radix Gentianae Macrophyllae 10 parts, Radix Achyranthis Bidentatae 10 parts, Radix Angelicae Pubescentis 10 parts, Rhizoma Et Radix Notopterygii 10 parts.
Treat the preparation method of joint disease medicine above in each embodiment, its special character is to comprise the following steps:
1, get the raw materials ready: take various raw material according to weight portion needed for each tcm components.
2, soak: the various raw materials taken by weight are put into ceramic medicinal cupping, add pure water and soak, 20 ~ 40 minutes time, amount of water requires to cover powder.
3, boil medicine: after intense fire is boiled, 20-40 minute at a simmer, filters out medicine juice; In medicinal cupping, add boiled water again, after intense fire is boiled, 15-25 minute at a simmer, leaches medicine juice again, by twice gained medicine juice mix homogeneously.
Drug administration method of the present invention: every day 1 dose, sooner or later taking, 10 days is 1 course for the treatment of.
Period in a medicine is avoided: treatment, period in a medicine taboo edible fried glutinous greasy, solid hard cold, food nondigestible and excitatory.

Claims (4)

1. treat a medicine for joint disease, it is characterized in that being made up of the raw material of following weight portion:
Cortex Acanthopancis 20-50 part, Flos Carthami 20-50 part, Rhizoma Chuanxiong 20-50 part, Radix Clematidis 10-30 part, Rhizoma Drynariae 10-30 part, Radix Saposhnikoviae 10-30 part, Olibanum 10-30 part, Radix Gentianae Macrophyllae 10-20 part, Radix Achyranthis Bidentatae 10-20 part, Radix Angelicae Pubescentis 10-20 part, Rhizoma Et Radix Notopterygii 10-20 part.
2., according to medicine for the treatment of joint disease a kind of described in claim 1, it is characterized in that being made up of the raw material of following weight portion:
Cortex Acanthopancis 30-40 part, Flos Carthami 30-40 part, Rhizoma Chuanxiong 30-40 part, Radix Clematidis 20-30 part, Rhizoma Drynariae 20-30 part, Radix Saposhnikoviae 20-30 part, Olibanum 20-30 part, Radix Gentianae Macrophyllae 20-20 part, Radix Achyranthis Bidentatae 10-20 part, Radix Angelicae Pubescentis 10-20 part, Rhizoma Et Radix Notopterygii 10-20 part.
3., according to medicine for the treatment of joint disease a kind of described in claim 1, it is characterized in that being made up of the raw material of following weight portion:
Cortex Acanthopancis 40 parts, 40 parts, Flos Carthami, Rhizoma Chuanxiong 40 parts, Radix Clematidis 25 parts, Rhizoma Drynariae 25 parts, Radix Saposhnikoviae 25 parts, Olibanum 25 parts, Radix Gentianae Macrophyllae 15 parts, Radix Achyranthis Bidentatae 15 parts, Radix Angelicae Pubescentis 15 parts, Rhizoma Et Radix Notopterygii 15 parts.
4. treat a preparation method for the medicine of joint disease, it is characterized in that comprising the following steps:
1), get the raw materials ready: take various raw material according to weight portion needed for each tcm components;
2), soak: the various raw materials taken by weight are put into ceramic medicinal cupping, add pure water and soak, 20 ~ 40 minutes time, amount of water requires to cover powder;
3), boil medicine: after intense fire is boiled, 20-40 minute at a simmer, filters out medicine juice; In medicinal cupping, add boiled water again, after intense fire is boiled, 15-25 minute at a simmer, leaches medicine juice again, by twice gained medicine juice mix homogeneously.
CN201310457737.1A 2013-09-30 2013-09-30 Medicine for treating osteoarticular diseases and preparation method thereof Pending CN104510792A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106266245A (en) * 2016-10-24 2017-01-04 王艳萍 A kind of auxiliary for fracture recovering cures pharmaceutical formulation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106266245A (en) * 2016-10-24 2017-01-04 王艳萍 A kind of auxiliary for fracture recovering cures pharmaceutical formulation

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Application publication date: 20150415