CN104510481A - Hypertension three-enzyme inhibitor vacuum blood collection tube and manufacturing method thereof - Google Patents
Hypertension three-enzyme inhibitor vacuum blood collection tube and manufacturing method thereof Download PDFInfo
- Publication number
- CN104510481A CN104510481A CN201310443864.6A CN201310443864A CN104510481A CN 104510481 A CN104510481 A CN 104510481A CN 201310443864 A CN201310443864 A CN 201310443864A CN 104510481 A CN104510481 A CN 104510481A
- Authority
- CN
- China
- Prior art keywords
- test tube
- tube
- blood collection
- anticoagulant
- hypertension
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/153—Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
- A61B5/154—Devices using pre-evacuated means
Abstract
Provided is a hypertension three-enzyme inhibitor vacuum blood collection tube, an opening plug and a cap used for sealing a blood collection test tube; an anticoagulation agent is arranged inside the blood collection test tube; the opening plug is made of a butyraldehyde rubber material; and the cap is made of a polyethylene material; the manufacturing method comprises the following steps: preparing the anticoagulation agent based on a mass mixing ratio that dimercaprol dimercaptopropanol:8-hydroxyquinoline sulfate:EDTA-k2 = 1:2:4; using a special machine to clean the inner wall of a test tube, and injecting the anticoagulation agent which is well mixed based on the ratio into the test tube in a super clean bench sterile environment; vacuuming based on the volume of the blood collection tube, and assembling the test tube with the safety cap; using an aluminum foil paper to package and keep the blood collection tube in a dark place after the blood collection tube is assembled, thus finishing manufacturing the vacuum blood collection tube; due to the anticoagulation agent is previously arranged inside the blood collection tube, tedious works such as clinically mixing the agent and adding into additives onsite are reduced, thus the blood sample collection is convenient, the work efficiency is increased and the detection effect is more precise.
Description
Technical field
The invention belongs to technical field of medical instruments, what be specifically related to is a kind of hypertension three enzyme inhibitor vacuum test tubes and preparation method thereof.
Background technology
At present, automatic ration blood-sampling method the most advanced is both at home and abroad blood sampling test tube evacuation blood collection method, and vacuum test tube specifically comprises following two kinds of modes: the first, directly by blood taking tube evacuation, and adds plug under vacuum conditions, and ensures certain vacuum; The second, by blood taking tube evacuation, then add noble gas (as the one in radon, nitrogen, argon, xenon, neon, and then evacuation, and adding plug under vacuum conditions); And hypertensive patient is suffered from for treatment, need the blood by extracting patient to diagnose, it is specifically carry out office hypertension by the detection of the plasma renin to hypertension human blood, Angiotensin II and aldosterone clinically; When wherein detecting plasma renin and Angiotensin II, its blood sample needs just can detect through the process of anticoagulant and enzyme inhibitor; Above-mentioned existing vacuum test tube can not provide anticoagulant and enzyme level system for the detection of plasma renin and Angiotensin II, so existing vacuum test tube can not be applicable to hypertensive blood testing completely, this case is life therefrom.
Summary of the invention
The object of the invention is the deficiency solving existing vacuum test tube, propose a kind of hypertension three enzyme inhibitor vacuum test tubes, conveniently detect plasma renin and Angiotensin II to solve.
Another object of the present invention is to the manufacture method that a kind of vacuum test tube is provided, to solve the defect for detecting plasma renin and Angiotensin II.
For achieving the above object, the technical solution used in the present invention is as follows:
The manufacture method of hypertension three enzyme inhibitor vacuum test tubes, comprises the following steps:
The first, anticoagulant composition is allocated, anticoagulant composition is made up of dimercaptopropanol, BAL, oxine sulfate and EDTA-k2, and its mass mixing ratio is dimercaptopropanol, BAL: oxine sulfate: EDTA-k2=(0.5 ~ 1.5): (1 ~ 3): (3 ~ 5).
The second, with special machine cleaning inboard wall of test tube, and under super-clean bench gnotobasis, in the allotment anticoagulant injecting tube proportionally mixed up.
Three, carry out evacuation according to the dosage of blood taking tube, and while evacuation, test tube and safety helmet are assembled.
Four, adopt aluminium-foil paper lucifuge packaging after blood taking tube assembling, vacuum test tube completes.
Preferably, the manufacture method of described hypertension three enzyme inhibitor vacuum test tubes, comprises following optimization procedure:
The first, allocate anticoagulant composition, anticoagulant composition is made up of dimercaptopropanol, BAL, oxine sulfate and EDTA-k2, and its mass mixing ratio is dimercaptopropanol, BAL: oxine sulfate: EDTA-k2=1:2:4.
The second, with special machine cleaning inboard wall of test tube, and under super-clean bench gnotobasis, in the allotment anticoagulant injecting tube proportionally mixed up.
Three, carry out evacuation according to the dosage of blood taking tube, and while evacuation, test tube and safety helmet are assembled.
Four, adopt aluminium-foil paper lucifuge packaging after blood taking tube assembling, vacuum test tube completes.
According to a further aspect in the invention, additionally provide a kind of hypertension three enzyme inhibitor vacuum test tubes, this vacuum test tube comprises blood sampling test tube, for sealing opening plug and the cap of blood sampling test tube, anticoagulant is provided with in blood sampling test tube, opening plug is that butyraldehyde elastomeric material is formed, and cap is that polythene material is formed.
The invention has the beneficial effects as follows: the present invention compared with prior art, due in vitro preset anticoagulant, thus decreases clinical configuration reagent and the on-the-spot tedious work adding additive, while increasing work efficiency, makes Detection results more accurate.
Accompanying drawing explanation
Fig. 1 is vacuum test tube structural representation of the present invention.
Under to be classified as in figure the concrete title of each mark: 1 anticoagulant, 2 blood sampling test tubes, 3 opening plugs, 4 caps.
Detailed description of the invention
Embodiment one:
The manufacture method of hypertension three enzyme inhibitor vacuum test tubes, comprises the following steps:
The first, allocate anticoagulant composition, anticoagulant composition is made up of dimercaptopropanol, BAL, oxine sulfate and EDTA-k2, and its mass mixing ratio is dimercaptopropanol, BAL: oxine sulfate: EDTA-k2=0.5:1:3.
The second, with special machine cleaning inboard wall of test tube, and under super-clean bench gnotobasis, in the allotment anticoagulant injecting tube proportionally mixed up.
Three, evacuation is carried out (according to blood sampling volume evacuation in blood taking tube according to the dosage of blood taking tube, such as blood sampling volume is two milliliters and then transfers two milliliters of vacuum, blood sampling volume is four milliliters and then transfers four milliliters of vacuum), and while evacuation, test tube and safety helmet are assembled.
Four, when above-mentioned steps blood taking tube completes, meeting light due to the reagent injected in blood taking tube can volatilize, and namely blood taking tube has assembled rear employing aluminium-foil paper lucifuge packaging, and the vacuum test tube after this packaging can reach the quality guarantee period of about 6 months.
Embodiment two:
The manufacture method of hypertension three enzyme inhibitor vacuum test tubes, comprises the following steps:
The first, allocate anticoagulant composition, anticoagulant composition is made up of dimercaptopropanol, BAL, oxine sulfate and EDTA-k2, and its mass mixing ratio is dimercaptopropanol, BAL: oxine sulfate: EDTA-k2=1:2:4.
The second, with special machine cleaning inboard wall of test tube, and under super-clean bench gnotobasis, in the allotment anticoagulant injecting tube proportionally mixed up.
Three, evacuation is carried out (according to blood sampling volume evacuation in blood taking tube according to the dosage of blood taking tube, such as blood sampling volume is two milliliters and then transfers two milliliters of vacuum, blood sampling volume is four milliliters and then transfers four milliliters of vacuum), and while evacuation, test tube and safety helmet are assembled.
Four, when above-mentioned steps blood taking tube completes, meeting light due to the reagent injected in blood taking tube can volatilize, and namely blood taking tube has assembled rear employing aluminium-foil paper lucifuge packaging, and the vacuum test tube after this packaging can reach the quality guarantee period of about 6 months.
Embodiment three:
The manufacture method of hypertension three enzyme inhibitor vacuum test tubes, comprises the following steps:
The first, allocate anticoagulant composition, anticoagulant composition is made up of dimercaptopropanol, BAL, oxine sulfate and EDTA-k2, and its mass mixing ratio is dimercaptopropanol, BAL: oxine sulfate: EDTA-k2=1.5:3:5.
The second, with special machine cleaning inboard wall of test tube, and under super-clean bench gnotobasis, in the allotment anticoagulant injecting tube proportionally mixed up.
Three, evacuation is carried out (according to blood sampling volume evacuation in blood taking tube according to the dosage of blood taking tube, such as blood sampling volume is two milliliters and then transfers two milliliters of vacuum, blood sampling volume is four milliliters and then transfers four milliliters of vacuum), and while evacuation, test tube and safety helmet are assembled.
Four, when above-mentioned steps blood taking tube completes, meeting light due to the reagent injected in blood taking tube can volatilize, and namely blood taking tube has assembled rear employing aluminium-foil paper lucifuge packaging, and the vacuum test tube after this packaging can reach the quality guarantee period of about 6 months.
The structure of the vacuum test tube made according to above-mentioned manufacture method as shown in Figure 1, this vacuum test tube comprises blood sampling test tube 2, for sealing opening plug 3 and the cap 4 of blood sampling test tube 2, anticoagulant 1 is provided with in blood sampling test tube 2, opening plug 3 is butyraldehyde elastomeric material formation, cap 4 is polythene material formation, and blood sampling test tube 2 is that PET material is formed.
During use, blood sample can be directly injected in blood sampling test tube, owing to presetting anticoagulant in blood sampling test tube, thus decreases clinical configuration reagent and the on-the-spot tedious work adding additive, for blood sampling sample brings great convenience.
Claims (3)
1. hypertension three enzyme inhibitor vacuum test tubes, it is characterized in that: this vacuum test tube comprises blood sampling test tube, for sealing opening plug and the cap of blood sampling test tube, be provided with anticoagulant in blood sampling test tube, opening plug is that butyraldehyde elastomeric material is formed, and cap is that polythene material is formed.
2. the manufacture method of hypertension according to claim 1 three enzyme inhibitor vacuum test tubes, comprise the following steps: the first, allocate anticoagulant composition, anticoagulant composition is made up of dimercaptopropanol, BAL, oxine sulfate and EDTA-k2, and its mass mixing ratio is dimercaptopropanol, BAL: oxine sulfate: EDTA-k2=(0.5 ~ 1.5): (1 ~ 3): (3 ~ 5); The second, with special machine cleaning inboard wall of test tube, and under super-clean bench gnotobasis, in the allotment anticoagulant injecting tube proportionally mixed up; Three, carry out evacuation according to the dosage of blood taking tube, and while evacuation, test tube and safety helmet are assembled; Four, adopt aluminium-foil paper lucifuge packaging after blood taking tube assembling, vacuum test tube completes.
3. the manufacture method of hypertension according to claim 2 three enzyme inhibitor vacuum test tubes, it is characterized in that: the first, allocate anticoagulant composition, anticoagulant composition is made up of dimercaptopropanol, BAL, oxine sulfate and EDTA-k2, and its mass mixing ratio is dimercaptopropanol, BAL: oxine sulfate: EDTA-k2=1:2:4.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310443864.6A CN104510481A (en) | 2013-09-26 | 2013-09-26 | Hypertension three-enzyme inhibitor vacuum blood collection tube and manufacturing method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310443864.6A CN104510481A (en) | 2013-09-26 | 2013-09-26 | Hypertension three-enzyme inhibitor vacuum blood collection tube and manufacturing method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104510481A true CN104510481A (en) | 2015-04-15 |
Family
ID=52786754
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310443864.6A Pending CN104510481A (en) | 2013-09-26 | 2013-09-26 | Hypertension three-enzyme inhibitor vacuum blood collection tube and manufacturing method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104510481A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105193427A (en) * | 2015-08-18 | 2015-12-30 | 福州长庚医疗器械有限公司 | Preparation method of blood collection tube containing sodium fluoride and potassium oxalate |
| CN105286885A (en) * | 2015-09-17 | 2016-02-03 | 安徽信灵检验医学科技有限公司 | Blood collection tube applicable to medical clinical examination and manufacturing method of blood collection tube |
| EP3427833A1 (en) | 2017-07-10 | 2019-01-16 | Victor Lind | A device for test preparation of blood for determination of glucose concentration in blood plasma |
| CN110074793A (en) * | 2019-06-03 | 2019-08-02 | 江西益康医疗器械集团有限公司 | A kind of preparation method of the vacuum blood collection tube containing anti-coagulants |
| CN111024960A (en) * | 2019-12-27 | 2020-04-17 | 广州阳普医疗科技股份有限公司 | Additive for detecting hypertension blood sample, kit and application |
Citations (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1030411A (en) * | 1987-06-22 | 1989-01-18 | 藤泽药品工业株式会社 | New amino acid derivatives, its preparation method and contain its pharmaceutical composition |
| CN1047870A (en) * | 1989-06-09 | 1990-12-19 | 拜尔公司 | Suppress the peptide class of feritin, their preparation method and their application aspect medical |
| CN1087625A (en) * | 1992-09-25 | 1994-06-08 | 比奥·梅加·贝林格尔·英格海姆研究公司 | N-(hydroxyethyl) succinic diamide derivative |
| US5344611A (en) * | 1993-06-14 | 1994-09-06 | Becton, Dickinson And Company | Vacuum actuated blood collection assembly including tube of clot-accelerating plastic |
| US6077235A (en) * | 1999-02-23 | 2000-06-20 | Becton, Dickinson And Company | Blood collection assembly and method therefor |
| CN101003834A (en) * | 2006-11-14 | 2007-07-25 | 南通大学附属医院 | Microflow controlled method for detecting subtypes of C 482T polymorphism of apolipoprotein CIII gene |
| CN101248998A (en) * | 2008-03-31 | 2008-08-27 | 天津超然生物技术有限公司 | Vacuum hemostix |
| CN201609371U (en) * | 2009-12-28 | 2010-10-20 | 田军 | Vacuum blood collection tube |
| CN201631679U (en) * | 2010-01-28 | 2010-11-17 | 赵丙全 | Disposable blood collection bag with double sample retaining tubes |
| CN202277339U (en) * | 2011-08-30 | 2012-06-20 | 付士明 | Vacuum blood collection tube of hypertension blood sample |
| CN202489959U (en) * | 2012-02-28 | 2012-10-17 | 徐大勇 | Vacuum blood collection tube for blood routine examination |
| CN202743630U (en) * | 2012-06-01 | 2013-02-20 | 付士明 | Lucifugal packing bag for vacuum blood collection tubes |
| WO2013114359A1 (en) * | 2012-01-31 | 2013-08-08 | Estar Technologies Ltd | System and method for producing interleukin receptor antagonist (ira) |
| CN203182917U (en) * | 2013-04-05 | 2013-09-11 | 江西3L医用制品集团股份有限公司 | Novel vacuum blood collection tube |
-
2013
- 2013-09-26 CN CN201310443864.6A patent/CN104510481A/en active Pending
Patent Citations (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1030411A (en) * | 1987-06-22 | 1989-01-18 | 藤泽药品工业株式会社 | New amino acid derivatives, its preparation method and contain its pharmaceutical composition |
| CN1047870A (en) * | 1989-06-09 | 1990-12-19 | 拜尔公司 | Suppress the peptide class of feritin, their preparation method and their application aspect medical |
| CN1087625A (en) * | 1992-09-25 | 1994-06-08 | 比奥·梅加·贝林格尔·英格海姆研究公司 | N-(hydroxyethyl) succinic diamide derivative |
| US5344611A (en) * | 1993-06-14 | 1994-09-06 | Becton, Dickinson And Company | Vacuum actuated blood collection assembly including tube of clot-accelerating plastic |
| US6077235A (en) * | 1999-02-23 | 2000-06-20 | Becton, Dickinson And Company | Blood collection assembly and method therefor |
| CN101003834A (en) * | 2006-11-14 | 2007-07-25 | 南通大学附属医院 | Microflow controlled method for detecting subtypes of C 482T polymorphism of apolipoprotein CIII gene |
| CN101248998A (en) * | 2008-03-31 | 2008-08-27 | 天津超然生物技术有限公司 | Vacuum hemostix |
| CN201609371U (en) * | 2009-12-28 | 2010-10-20 | 田军 | Vacuum blood collection tube |
| CN201631679U (en) * | 2010-01-28 | 2010-11-17 | 赵丙全 | Disposable blood collection bag with double sample retaining tubes |
| CN202277339U (en) * | 2011-08-30 | 2012-06-20 | 付士明 | Vacuum blood collection tube of hypertension blood sample |
| WO2013114359A1 (en) * | 2012-01-31 | 2013-08-08 | Estar Technologies Ltd | System and method for producing interleukin receptor antagonist (ira) |
| CN202489959U (en) * | 2012-02-28 | 2012-10-17 | 徐大勇 | Vacuum blood collection tube for blood routine examination |
| CN202743630U (en) * | 2012-06-01 | 2013-02-20 | 付士明 | Lucifugal packing bag for vacuum blood collection tubes |
| CN203182917U (en) * | 2013-04-05 | 2013-09-11 | 江西3L医用制品集团股份有限公司 | Novel vacuum blood collection tube |
Non-Patent Citations (1)
| Title |
|---|
| 徐廷云: "真空采血管对血液常规检测结果影响分析", 《临床医学工程》 * |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105193427A (en) * | 2015-08-18 | 2015-12-30 | 福州长庚医疗器械有限公司 | Preparation method of blood collection tube containing sodium fluoride and potassium oxalate |
| CN105286885A (en) * | 2015-09-17 | 2016-02-03 | 安徽信灵检验医学科技有限公司 | Blood collection tube applicable to medical clinical examination and manufacturing method of blood collection tube |
| EP3427833A1 (en) | 2017-07-10 | 2019-01-16 | Victor Lind | A device for test preparation of blood for determination of glucose concentration in blood plasma |
| CN110074793A (en) * | 2019-06-03 | 2019-08-02 | 江西益康医疗器械集团有限公司 | A kind of preparation method of the vacuum blood collection tube containing anti-coagulants |
| CN111024960A (en) * | 2019-12-27 | 2020-04-17 | 广州阳普医疗科技股份有限公司 | Additive for detecting hypertension blood sample, kit and application |
| CN111024960B (en) * | 2019-12-27 | 2023-02-17 | 广州阳普医疗科技股份有限公司 | Additive for detecting hypertension blood sample, kit and application |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104510481A (en) | Hypertension three-enzyme inhibitor vacuum blood collection tube and manufacturing method thereof | |
| CN212379404U (en) | Sleeve grout outlet pipe convenient to detect grout plumpness | |
| CN202277339U (en) | Vacuum blood collection tube of hypertension blood sample | |
| CN204656570U (en) | A kind of hydrops censorship test tube | |
| CN105651554A (en) | Collection device and collection method of concrete pore solution | |
| CN204474672U (en) | A set of device for sampling microorganisms from surface of object | |
| CN206708735U (en) | A kind of gas pipeline leakproof monitoring device | |
| CN204556194U (en) | A kind of water pipe head air tightness test frock | |
| CN204964240U (en) | Rapid sampling ware of no dead volume | |
| CN203231876U (en) | Glove leak detector applied to portable isolator | |
| CN203396593U (en) | Contact biomaterial DNA (deoxyribonucleic acid) collection and storage device | |
| CN207220822U (en) | A kind of fully-automatic equipment vacuum blood clotting pipe | |
| CN106769346B (en) | Method for analyzing hydrogen isotopes in water | |
| CN105258976A (en) | Saliva collection device | |
| CN206687718U (en) | A kind of Multifunctional blood taking pipe | |
| CN206431146U (en) | A kind of heavy duty detergent vacuum blood clotting pipe | |
| CN204484133U (en) | A kind of vacuum test tube | |
| CN203178092U (en) | Fecal specimen treatment tube | |
| CN207075902U (en) | A kind of fully-automatic equipment vacuum blood collection tube | |
| CN211042616U (en) | Air pump plastic part airtightness detection jig | |
| CN203455199U (en) | Exhaust gas collecting device for exhaust gas detection | |
| CN201585992U (en) | Blood routine vacuum blood collection tube | |
| CN219495815U (en) | Sampling device for oxygen concentration detection | |
| CN205786505U (en) | A kind of anchoring type sound detecting pipe | |
| CN203385576U (en) | Specified depth sampler |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20150415 |
|
| RJ01 | Rejection of invention patent application after publication |