CN104492348A - Fluidized bed used for preparing granular pills - Google Patents
Fluidized bed used for preparing granular pills Download PDFInfo
- Publication number
- CN104492348A CN104492348A CN201410717259.8A CN201410717259A CN104492348A CN 104492348 A CN104492348 A CN 104492348A CN 201410717259 A CN201410717259 A CN 201410717259A CN 104492348 A CN104492348 A CN 104492348A
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- CN
- China
- Prior art keywords
- sieve plate
- casing
- fluidized bed
- box body
- shaft
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J8/00—Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes
- B01J8/18—Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes with fluidised particles
- B01J8/24—Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes with fluidised particles according to "fluidised-bed" technique
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/06—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of pills, lozenges or dragees
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2208/00—Processes carried out in the presence of solid particles; Reactors therefor
- B01J2208/00796—Details of the reactor or of the particulate material
- B01J2208/00893—Feeding means for the reactants
- B01J2208/00911—Sparger-type feeding elements
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Combustion & Propulsion (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Devices And Processes Conducted In The Presence Of Fluids And Solid Particles (AREA)
Abstract
The invention discloses a fluidized bed used for preparing granular pills. The fluidized bed comprises a fluidized bed box body, a sieve plate used for accommodating materials, a wind inlet, a wind outlet, a material inlet, a material outlet and nozzles. The sieve plate is arranged in the middle of the box body and divides the fluidized bed box body into an upper layer and a lower layer, the wind inlet is formed in the side wall of the lower layer, the material inlet is formed in the upper end of the upper layer, and the material outlet is formed in the side wall of the box body above the sieve plate. A liquid inlet pipe is arranged above the upper layer of the box body, and is provided with more than two nozzles evenly distributed above the box body. The fluidized bed further comprises a stirring device; the stirring device comprises a motor, a speed reducer, a stirring shaft and stirring blades; the motor is connected with the stirring shaft through the speed reducer, and drives the stirring shaft to move; the stirring shaft passes through the sieve plate from bottom to top and is fixedly connected with the stirring blades. The fluidized bed is provided with the stirring device, blocky materials can be broken and dispersed by adjusting the stirring speed, caking phenomena are few, the thermal energy utilization ratio is high, the qualified product rate is high, and the dust content is low.
Description
Technical field
The invention belongs to technical field of chemical, especially relate to a kind of fluid bed for the preparation of granular pill.
Background technology
Fluid bed reacts setting efficiently as one, is mainly used to carry out gas-solid phase reaction and liquid and solid phase reaction, has been widely used in the fields such as chemical industry, pharmacy, environmental protection.Fluid bed is when utilizing air-flow to act between the critical speed and carrying velocity of dried material particle swarm, makes particle form the motion of fluidisation shape, thus the mass transfer of both reinforcements and heat transfer.Production practices show, fluid bed is used as reacting appliance and has many good qualities, such as: axial back mixing ability is strong; Micromixing degree is high; When complete mixing flow is beneficial to reaction, conversion ratio can be improved; Can obtain uniform Temperature Distribution under the condition without additional measure, because fluidization has the feature of mixing and heat transfer rapidly, many processes being difficult to carry out in General reactions device can be resolved by fluidization technology; Heat is introduced convenient, shifts out easily; Temperature controls convenient; Catalyst be easy to change and liquid distribution degree of irregularity minimum etc.
By fluidized bed applications in granular pill manufacture is produced, make material dispersion and drying with gas, fluosolids uppermost spray liquid, make liquid be wrapped in material and form granular pill.When the material that drying process water content is larger or adhesiveness is strong, easily cause material not disperse fully and condense into the problem of block, these materials only can be surperficial dried, and can sink to bottom fluosolids, not only hinder the ejection of flowing gas, also affect the formation of fluosolids, therefore, have the possibility causing goods fluid inequality or produce dead angle phenomenon.In operation, can increase air quantity and the lump material be trapped in bottom fluosolids is moved, but this can cause the consumption of more multiple-energy-source on the one hand, and normal granules can be made again to disperse, the formation that may affect granular pill increases dust.
Summary of the invention
In order to overcome the deficiencies in the prior art, the invention provides a kind of caking phenomenon few, heat utilization rate is high, and it is high that product produces qualification rate, the fluid bed for the preparation of granular pill that dust content is few.
A kind of fluid bed for the preparation of granular pill, comprise casing, for holding the sieve plate of material, air inlet, air outlet, discharging opening and shower nozzle, described sieve plate is placed in box house, and casing is divided into the upper and lower, and described air inlet is positioned on the sidewall of lower floor, air outlet is arranged on the upper end on upper strata, and discharging opening is arranged on the wall box above sieve plate; Described feed tube is arranged on the top on casing upper strata, and feed tube is provided with plural shower nozzle, and shower nozzle is evenly distributed in above casing, and it also comprises agitating device; Described agitating device comprises motor, decelerator, shaft and stirring vane; Described motor is connected with shaft by decelerator, drives shaft motion; Described shaft is fixedly connected with stirring vane through sieve plate from lower to upper.
Above-described stirring vane is rake stirring vane.
Above-described motor, decelerator and be all coated with bucker on being positioned at below screen cloth shaft, can avoid the equipment such as motor, decelerator to be etched, extension device service life.
Above-described air inlet arranges gas distributor; Described gas distributor comprises plate, and plate is evenly provided with through hole.
Compared to prior art, the present invention has the following advantages and good effect:
1, the present invention arranges agitating device, and by regulating mixing speed, can make lump material fragmentation dispersion, reducing caking phenomenon, even if do not increase air quantity, material also can not be deposited on fluid bed bottom in bulk, namely there will not be dead angle phenomenon; In addition, also can not affect gas and spray from sieve plate, fluidisation is even, and heat utilization rate is high, and dust content is few, thus can make material fully drying or bag quilt, and the granular pill product percent of pass of formation is high.
2, the present invention sets up a gas distributor at air inlet, and gas is air-flow redistribution after gas distributor, decreases the impact of rope flow on distribution of gas in fluid bed, and the fluidized state of fluid bed is stablized; Entering fluid bed in addition can effectively avoid material to lump gas uniform, prevents dead bed phenomenon from occurring.
3, paddle is set to rake structure by the present invention, optimize while mixing effect can also the effective caking materials that is attached on sieve plate of fragmentation dispersion, extends the service life of sieve plate.
4, structure of the present invention is simple, easy to operate, and power consumption is few, long service life, is applicable to promotion and application.
During use, gas is after the gas distributor of air inlet, enter equably in fluid bed, due to blowing of bottom gas, make the material particles strenuous exercise above sieve plate, dispersion, be suspended in casing, the shower nozzle above casing upper strata sprays into liquid, liquid is bonded at material particles and forms pill on the surface, and now granular pill is still suspended in casing; Start agitating device, under the rotation of stirring vane, granular pill contacts with flowing gas and dry, and fluidisation is even, and granular pill is fully dry, and epigranular, finished product is discharged from discharging opening simultaneously.
Accompanying drawing explanation
Fig. 1 is structural representation of the present invention.
Accompanying drawing identifies:
1-casing, 2-discharging opening, 3-sieve plate, 4-shaft, 5-motor, 6-decelerator, 7-gas distributor, 8-air inlet, 9-stirring vane, 10-shower nozzle, 11-feed tube, 12-air outlet.
Detailed description of the invention
Below in conjunction with the drawings and specific embodiments, the invention will be further described.
Embodiment 1:
A kind of fluid bed for the preparation of granular pill, comprise casing 1, for holding the sieve plate 3 of material, air inlet 8, feed tube 11, air outlet 12, discharging opening 2 and shower nozzle 10, it is inner that described sieve plate 3 is placed in casing 1, casing 1 is divided into the upper and lower, described air inlet 8 is positioned on the sidewall of lower floor, and air outlet 12 is arranged on the upper end on upper strata, and discharging opening 2 is arranged on casing 1 sidewall above sieve plate 3; Described feed tube 11 is arranged on the top on casing 1 upper strata, and feed tube 11 is provided with the shower nozzle 10 of two, and shower nozzle 10 is evenly distributed in above casing 1, it is characterized in that: it also comprises agitating device; Described agitating device comprises motor 5, decelerator 6, shaft 4 and stirring vane 9; Described motor 5 is connected with shaft 4 by decelerator 6, drives shaft 4 to move; Described shaft 4 is fixedly connected with stirring vane 9 through sieve plate 3 from lower to upper.Described stirring vane 9 is rake stirring vane 9.Described motor 5, decelerator 6 and be all coated with bucker on being positioned at below screen cloth shaft 4, can avoid the equipment such as motor, decelerator to be etched, extension device service life.Described air inlet 8 place arranges gas distributor 7; Described gas distributor 7 comprises plate, and plate is evenly provided with through hole, and gas is air-flow redistribution after gas distributor 7, decreases the impact of rope flow on distribution of gas in fluid bed, and the fluidized state of fluid bed is stablized.
During use, gas is after the gas distributor 7 of air inlet 8, enter equably in fluid bed, due to blowing of bottom gas, make the material particles strenuous exercise above sieve plate 3, dispersion, be suspended in casing 1, liquid is passed into feed tube 11, in fluid bed, spray into liquid through shower nozzle 10, liquid is bonded at material particles and forms pill on the surface, and now granular pill is still suspended in casing 1; Start agitating device, under the rotation of stirring vane 9, granular pill contacts with flowing gas and dry, and fluidisation is even, and granular pill is fully dry, and epigranular, finished product is discharged from discharging opening 2 simultaneously.
Embodiment 2:
A kind of fluid bed for the preparation of granular pill, comprise casing 1, for holding the sieve plate 3 of material, air inlet 8, feed tube 11, air outlet 12, discharging opening 2 and shower nozzle 10, it is inner that described sieve plate 3 is placed in casing 1, casing 1 is divided into the upper and lower, described air inlet 8 is positioned on the sidewall of lower floor, and air outlet 12 is arranged on the upper end on upper strata, and discharging opening 2 is arranged on casing 1 sidewall above sieve plate 3; Described feed tube 11 is arranged on the top on casing 1 upper strata, and feed tube 11 is provided with six shower nozzles 10, and shower nozzle 10 is evenly distributed in above casing 1, it is characterized in that: it also comprises agitating device; Described agitating device comprises motor 5, decelerator 6, shaft 4 and stirring vane 9; Described motor 5 is connected with shaft 4 by decelerator 6, drives shaft 4 to move; Described shaft 4 is fixedly connected with stirring vane 9 through sieve plate 3 from lower to upper.Described stirring vane 9 is rake stirring vane 9.Described motor 5, decelerator 6 and be all coated with bucker on being positioned at below screen cloth shaft 4, can avoid the equipment such as motor, decelerator to be etched, extension device service life.Described air inlet 8 place arranges gas distributor 7; Described gas distributor 7 comprises plate, and plate is evenly provided with through hole, and gas is air-flow redistribution after gas distributor 7, decreases the impact of rope flow on distribution of gas in fluid bed, and the fluidized state of fluid bed is stablized.
The operation principle of this embodiment is identical with embodiment 1.
Claims (4)
1. the fluid bed for the preparation of granular pill, comprise casing (1), for holding the sieve plate (3) of material, air inlet (8), feed tube (11), air outlet (12), discharging opening (2) and shower nozzle (10), it is inner that described sieve plate (3) is placed in casing (1), casing (1) is divided into the upper and lower, described air inlet (8) is positioned on the sidewall of lower floor, and air outlet (12) is arranged on the upper end on upper strata, and discharging opening (2) is arranged on casing (1) sidewall of sieve plate (3) top; Described feed tube (11) is arranged on the top on casing (1) upper strata, and feed tube (11) is provided with plural shower nozzle (10), and shower nozzle (10) is evenly distributed in casing (1) top, it is characterized in that: it also comprises agitating device; Described agitating device comprises motor (5), decelerator (6), shaft (4) and stirring vane (9); Described motor (5) is connected with shaft (4) by decelerator (6), drives shaft (4) motion; Described shaft (4) is fixedly connected with stirring vane (9) through sieve plate (3) from lower to upper.
2. a kind of fluid bed for the preparation of granular pill according to claim 1, is characterized in that: described stirring vane (9) is rake stirring vane (9).
3. according to the arbitrary described a kind of fluid bed for the preparation of granular pill of claim 1 or 2, it is characterized in that: described motor (5), decelerator (6) and be all coated with bucker on being positioned at below screen cloth shaft (4).
4., according to the arbitrary described a kind of fluid bed for the preparation of granular pill of claim 1 or 2, it is characterized in that: described air inlet (8) place arranges gas distributor (7); Described gas distributor (7) comprises plate, and plate is evenly provided with through hole.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410717259.8A CN104492348A (en) | 2014-11-30 | 2014-11-30 | Fluidized bed used for preparing granular pills |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410717259.8A CN104492348A (en) | 2014-11-30 | 2014-11-30 | Fluidized bed used for preparing granular pills |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104492348A true CN104492348A (en) | 2015-04-08 |
Family
ID=52933850
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410717259.8A Pending CN104492348A (en) | 2014-11-30 | 2014-11-30 | Fluidized bed used for preparing granular pills |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104492348A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107875987A (en) * | 2017-12-30 | 2018-04-06 | 唐山三友化工股份有限公司 | Prepare the stirred reactor of dihydrate gypsum crystal |
| CN109699986A (en) * | 2018-12-29 | 2019-05-03 | 明富（上海）健康科技有限公司 | A kind of equipment and its production method of industrialized production grease embedding acid particle |
| CN112403732A (en) * | 2020-11-11 | 2021-02-26 | 安徽萨普丽生物医药有限公司 | Even capsule machine of capsule |
| CN113876585A (en) * | 2021-09-30 | 2022-01-04 | 浙江亚峰药厂有限公司 | Preparation system and process of pediatric paracetamol, atificial cow-bezoar and chlorphenamine maleate granules |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1087026A (en) * | 1992-09-25 | 1994-05-25 | 武田药品工业株式会社 | The method of granulating of crude drug and solid preparation |
-
2014
- 2014-11-30 CN CN201410717259.8A patent/CN104492348A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1087026A (en) * | 1992-09-25 | 1994-05-25 | 武田药品工业株式会社 | The method of granulating of crude drug and solid preparation |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107875987A (en) * | 2017-12-30 | 2018-04-06 | 唐山三友化工股份有限公司 | Prepare the stirred reactor of dihydrate gypsum crystal |
| CN109699986A (en) * | 2018-12-29 | 2019-05-03 | 明富（上海）健康科技有限公司 | A kind of equipment and its production method of industrialized production grease embedding acid particle |
| CN109699986B (en) * | 2018-12-29 | 2022-08-26 | 明富（上海）健康科技有限公司 | Equipment for industrially producing oil embedded sour agent particles and production method thereof |
| CN112403732A (en) * | 2020-11-11 | 2021-02-26 | 安徽萨普丽生物医药有限公司 | Even capsule machine of capsule |
| CN113876585A (en) * | 2021-09-30 | 2022-01-04 | 浙江亚峰药厂有限公司 | Preparation system and process of pediatric paracetamol, atificial cow-bezoar and chlorphenamine maleate granules |
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| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20150408 |
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| RJ01 | Rejection of invention patent application after publication |