CN104490488B - A kind of serum level controls device - Google Patents
A kind of serum level controls device Download PDFInfo
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- CN104490488B CN104490488B CN201410835927.7A CN201410835927A CN104490488B CN 104490488 B CN104490488 B CN 104490488B CN 201410835927 A CN201410835927 A CN 201410835927A CN 104490488 B CN104490488 B CN 104490488B
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- rat
- assembly
- fixed station
- therapeutic drug
- head
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
Abstract
A kind of serum level controls device, including support table body, tail restraining belt, column gear transmission assembly, tail fixed support, Worm Wheel System assembly, rat fixed station assembly, therapeutic drug monitoring assembly, drug injection assembly and external computer controller etc., external computer controller and each functional areas are connected by electric wire and realize the control to functional areas.This serum level controls device to be fixed rat, fluorescence intensity this principle relevant with drug level that therapeutic drug monitoring assembly sends after light irradiates according to some medicines carries out real-time therapeutic drug monitoring to rat, the signal of monitoring is passed to external computer controller, external computer controller is after processing and judging, assign the instruction whether injecting medicine to drug injection assembly, keep or adjust the stable or scope of blood drug level in rat body.This device can control serum level well, have advantage real-time, efficient.
Description
Technical field
The present invention relates to a kind of medical experiment device, fix particularly to one collection rat, blood medicine
The several functions such as concentration monitor and drug injection is in the control device of one.
Background technology
Along with the development of the technology such as modern medicine and biology, zoopery is widely used in many
First-selected experimental subject in medical research, during wherein rat is research mostly.At a medical science medicine
In thing experiment, experimenter wishes that blood drug level keeps relative stability in most cases, existing control
Device processed seldom there is such blood drug level control device；The control of such blood drug level need to have
Fixing device, therapeutic drug monitoring device and medicine supplementary device, existing instrument typically can only
Realize one of the above or two kinds of functions, be difficult to three kinds of functions and realize simultaneously；The most existing rat
Though fixing device has certain development, but the certain operations after fixing not only regulates by manpower, and
And be difficult to operation and put in place, as by angle certain for rat axial-rotation, bent certain angle etc.
Operation, these operations are conducive to therapeutic drug monitoring position and the determination of drug injection position.
Summary of the invention
The invention aims to provide a kind of serum level to control device, this control device
Merits such as being automatically adjusted is supplemented by fixing rat, auto-real-time monitoring serum level, medicine
Can, keep or adjust the stable or scope of blood drug level in rat body, have simple operation,
Efficiently, safety high.
The technical scheme is that
A kind of serum level controls device, including support table body, tail restraining belt, cylinder
Gear drive assembly, tail fixed support, Worm Wheel System assembly, rat fixed station assembly,
Therapeutic drug monitoring assembly, drug injection assembly and external computer controller.External computer
Controller and each functional areas are connected by electric wire and realize the control to functional areas.Described support desk
Its structure of body is that centre has rectangular opening, and it is T-shaped groove that rectangular opening both sides desktop is provided with cross section
Support desk support desk track, rectangular opening two ends inwall is provided with installs rat fixed station assembly
Dead eye, offers tail fixed groove, tail anchor in the middle of the desktop of rat tails side
Groove has tail restraining belt lock hole on one side, and the support of described support table body is by the four of distribution corner
Individual support table leg is constituted.
Above-mentioned column gear transmission assembly, including motor, motor travelling gear,
Motor mounting bracket and control module.Described motor, motor travelling gear,
Motor mounting bracket, control module be unified to be installed on immediately below tail fixed groove under desk body
On wall, column gear transmission assembly realizes rat by driving rat fixed station driven gear
The axial-rotation of fixed station assembly.
Above-mentioned rat fixed station assembly is arranged on the dead eye in the rectangular opening of support table body,
By rat fixed station body, restraining, tie up that lower limb links closely, fixed helmet forms.Described rat is solid
Determining table top in the middle of playscript with stage directions body is arcwall face, and this rat fixed station body includes folding pin, rat
Fixed station driven gear, rat fixed station driven gear shaft, rat fixed station support desk track,
Folding stand on lifting jack support desk track, lifting jack, rat fixed station, lifting jack drive mechanism,
The driven fixing axle of rat fixed station, fixed helmet installing hole, fold pin and rat fixed the playscript with stage directions
Body is hinged with folding stand on rat fixed station, rat fixed station driven gear and column gear transmission
The motor travelling gear of assembly is engaged transmission；Rat fixed station support desk track is transversal
Face is the groove of T-shaped, lays respectively at folding stand on rat fixed station body and rat fixed station
Both sides, are used for fixing spud pile.Folding stand on lifting jack lifting rat fixed station, is used for regulating
The angle of bend of rat, the support desk track of its trend is exactly described lifting jack support desk rail
Road, lifting jack drive mechanism provides power, lifting jack to include lifting push rod, slip to lifting jack
Axle, lifting jack worm screw, lifting jack worm screw forms Worm Wheel System machine with lifting jack drive mechanism
Structure, its power source is the motor in lifting jack drive mechanism, and lifting push rod is fixed with rat
Folding stand bottom surface on platform, sliding axle are hinged.Fixed helmet mounting hole site is in above-mentioned rat fixed station
Upper folding stand head end, is used for installing fixed helmet.
Above-mentioned spud pile, is made up of wishbone, clamp nut and spud pile guide pad, fork-shaped
Bar divaricates and up-thin-low-thick, and therefore fork portion has certain elastic force, and this elastic force will just
Wishbone fixes with rat fixed station support desk track, wishbone has and coordinates with clamp nut
Screw thread, is rotated down clamp nut and can reduce wishbone to rat fixed station support desk track
Active force, make whole spud pile move along rat fixed station support desk track.Restraining, tie up
Lower limb links closely and is arranged on above-mentioned spud pile, is used for fixing rat.Restraining, tie up lower limb and link closely adjacent
The one side of rat uses soft precoat, prevents rat injured.Tie up lower limb to link closely and include fastening strip
With fastening strip snap ring, between fastening strip snap ring and fastening strip, there is certain frictional force.
Above-mentioned fixed helmet is arranged on fixing head at fixed helmet installing hole and by rod member
Helmet is connected with folding stand on rat fixed station, and this fixed helmet includes pneumostome, neck tension band
With eyes mouth, it is used for fixing rat head.
Above-mentioned therapeutic drug monitoring assembly is arranged on above-mentioned support desk support desk track, including
Pull-switch, syringe needle tube, fiber pipe, fiber probe sensor, base, mechanical arm, spherical
Joint, mechanical hand head, probe-head control module and therapeutic drug monitoring minisize pick-up head.Described
Pull-switch can realize syringe needle tube, fiber pipe is connected with the plug of mechanical hand head, it is simple to detection
Change and maintenance.Described fiber pipe, fiber probe sensor are installed in above-mentioned syringe needle tube, real
It is put in together with syringe needle tube in rat body when testing；Fiber probe sensor is rotatable, by launching
Receive from the fluorescence in blood after the light of some strength, the signal of acquisition is sent to control of popping one's head in
Module, passes to external computer controller by signal, the most just after probe-head control module processes
Blood drug level can be monitored in real time；Described therapeutic drug monitoring minisize pick-up head is arranged on above-mentioned machinery
At hand in portion, for showing high definition enlarged drawing picture on external computer control display and recording
Picture, in order to preferably complete monitoring business.
It is another that above-mentioned drug injection assembly is arranged on therapeutic drug monitoring assembly relative bearing
On the support desk track of side, mainly include drug injection minisize pick-up head, administration needle head, electromagnetism
Valve, cooling water jacket, Hydraulic pump, Stress control and relief valve, grug transportation tube, grug transportation tube joint
Nut, syringe cavity, cooling water liquid return hole.Described minisize pick-up head is total with therapeutic drug monitoring
Therapeutic drug monitoring miniature video camera camera function in one-tenth is identical, is used for the most here monitoring and record
The situation of acupuncture treatment position.Described cooling water jacket uses light screening material to make, and protects for meeting needs
Hold uniform temperature or need the medicine requirement of shading；Hydraulic pump, Stress control and relief valve are used for will
Teat pipette in storing medicine bottle is to syringe cavity and keeps or the pressure of regulation syringe cavity.Drug injection
Assembly has base, mechanical arm and the spherical pass consistent with therapeutic drug monitoring assembly equally
Joint, the position of syringe cavity is equivalent to the position of therapeutic drug monitoring assembly mechanical hand head.Logical
Crossing therapeutic drug monitoring assembly feedack, drug injection assembly accepts external computer control
The instruction of device supplements medicament to rat, regulates blood drug level, makes up to requirement of experiment.
Above-mentioned Worm Wheel System assembly totally two groups, all include controllable motor, worm screw,
Base worm gear and worm-wheel shaft.Worm screw is installed in support desk support desk track, base worm gear and snail
Wheel shaft is arranged on above-mentioned therapeutic drug monitoring assembly base and drug injection assembly base, can divide
Do not drive and regulate therapeutic drug monitoring assembly and drug injection assembly on support desk track
Position.
The present invention is supplemented certainly by fixing rat, auto-real-time monitoring serum level, medicine
The functions such as dynamic regulation, keep or adjust the stable or scope of blood drug level in rat body.It is one
Kind can control the device of serum level well, have simple operation, efficient, safety
High advantage.
Accompanying drawing explanation
Fig. 1 is the structural representation of the present invention.
Fig. 2 is the rat fixed station structural representation of the present invention.
Fig. 3 is the lifting jack structural representation of the present invention.
Fig. 4 is the spud pile structural representation of the present invention.
Fig. 5 be the present invention tie up lower limb fastening structure schematic diagram.
Fig. 6 is the fixed helmet structural representation of the present invention.
Fig. 7 is the therapeutic drug monitoring assembly structure schematic diagram of the present invention.
Fig. 8 is the drug injection assembly structure schematic diagram of the present invention.
Fig. 9 is the Worm Wheel System assembly structure schematic diagram of the present invention.
Concrete described mode
A kind of serum level controls device, including support table body 1, tail restraining belt 2,
Column gear transmission assembly 3, tail fixed support 5, Worm Wheel System assembly 7, rat
Fixed station assembly 8, therapeutic drug monitoring assembly 9, drug injection assembly 17 and external computer
Controller 66.External computer controller 66 is connected to come real with each functional areas by electric wire 67
The now control to functional areas.Described its structure of support table body 1 is that centre has rectangular opening 16,
Rectangular opening 16 both sides desktop is provided with the support desk support desk track 10 that cross section is T-shaped groove,
Rectangular opening 16 two ends inwall is provided with the dead eye 15 installing rat fixed station assembly 8, rat
Offering tail fixed groove 4 in the middle of the desktop of afterbody side, tail fixed groove 4 sets on one side
Having tail restraining belt lock hole 6, the support of described support table body 1 is by four of distribution corner
Support table leg 11 to constitute.
Described column gear transmission assembly 3 include motor, motor travelling gear,
Motor mounting bracket and control module etc., described motor, motor travelling gear,
Motor mounting bracket, control module are unified is installed on desk body immediately below tail fixed groove 4
On lower wall surface, column gear transmission assembly 3 is by driving rat fixed station driven gear 20
Realize the axial-rotation of rat fixed station assembly 8.
Described rat fixed station assembly 8 is arranged on the axle in the rectangular opening 16 of support table body 1
In bearing bore 15, by rat fixed station body 19, restraining 12, tie up lower limb link closely 13, fixing
The helmet 14 forms.The middle table top of described rat fixed station body 19 is arcwall face, and this rat is solid
Determine playscript with stage directions body include fold pin 18, rat fixed station driven gear 20, rat fixed station from
Movable gear shaft 21, rat fixed station support desk track 22, lifting jack support desk track 23, act
Rise folding stand 25, lifting jack drive mechanism 26, rat fixed station on device 24, rat fixed station
Driven fixing axle 27, fixed helmet installing hole 28 (see Fig. 2).Fold pin 18 by rat
Fixed station body 19 is hinged with folding stand 25 on rat fixed station, rat fixed station driven gear
20 are engaged transmission with the motor travelling gear of column gear transmission assembly 3.Rat
Fixed station support desk track 22 cross section is the groove of T-shaped, lays respectively at rat and fixes the playscript with stage directions
The both sides of folding stand 25 on body 19 and rat fixed station, are used for fixing spud pile 36.Lifting
Device 24 lifts folding stand 25 on rat fixed station, and for regulating the angle of bend of rat, it is walked
To support desk track be exactly described lifting jack support desk track 23, lifting jack drive mechanism
26 give lifting jack 24 provide power, lifting jack 24 include lift push rod 30, sliding axle 31,
Lifting jack worm screw 32 (see Fig. 3).Lifting jack worm screw 32 forms with lifting jack drive mechanism 26
Worm and worm-wheel gearing, its power source is the motor in lifting jack drive mechanism 26,
Lifting push rod 30 and folding stand bottom surface 29 on rat fixed station, sliding axle 31 are hinged.Fixing
Helmet installing hole 28 is positioned at folding stand 25 head end on above-mentioned rat fixed station, is used for installing admittedly
Determine the helmet 14 (see Fig. 2).
Described spud pile 36 is by wishbone 33, clamp nut 34 and spud pile guide pad 35
Composition (see Fig. 4).Wishbone 33 divaricates and up-thin-low-thick, and therefore fork portion has one
Fixed elastic force, wishbone is fixed by this elastic force with rat fixed station support desk track 22 just,
There is the screw thread coordinated with clamp nut 34 on wishbone 33, clamp nut is rotated down
Reduce the wishbone 33 active force to rat fixed station support desk track 22, make whole spud pile
36 are moved along rat fixed station support desk track 22 by spud pile guide pad 35.Restraining
12, tie up lower limb to link closely and 13 be arranged on above-mentioned spud pile 36, be used for fixing rat.Restraining
12, tie up the link closely one side of 13 adjacent rats of lower limb and use soft precoat, prevent rat injured.
Tie up lower limb to link closely and 13 include fastening strip 37 and fastening strip snap ring 38, fastening strip snap ring 38 with link closely
Certain frictional force (see Fig. 5) is had between 37.
Described fixed helmet 14 is arranged on solid at fixed helmet installing hole 28 and by rod member
Determine the helmet to be connected with folding stand 25 on rat fixed station, this fixed helmet include pneumostome 39,
Neck tension band 40 and eyes mouth 41, be used for fixing rat head (see Fig. 6).
Described therapeutic drug monitoring assembly 9 is arranged on above-mentioned support desk support desk track 10,
Including pull-switch 42, syringe needle tube 43, fiber pipe 44, fiber probe sensor 45, base
46, mechanical arm 47, spherical joint 48, mechanical hand head 49, probe-head control module 50 and
Therapeutic drug monitoring minisize pick-up head 51 (see Fig. 7).Described pull-switch 42 can realize syringe needle
Pipe 43, fiber pipe 44 are connected with the plug of mechanical hand head 49, it is simple to detection is changed and dimension
Repair.Described fiber pipe 44, fiber probe sensor 45 are installed in above-mentioned syringe needle tube 43,
It is put in together with syringe needle tube in rat body during experiment.Fiber probe sensor 45 is rotatable, logical
Receive from the fluorescence in blood after crossing the light of transmitting some strength, be sent to the signal of acquisition visit
Head control module 50, passes to external computer control after probe-head control module processes by signal
Device 66, the most just can monitor blood drug level in real time.Described therapeutic drug monitoring minisize pick-up head
51 are arranged on above-mentioned mechanical hand head 49, for showing at external computer control 66
Show high definition enlarged drawing picture on device and record a video, in order to preferably completing monitoring business.
Described drug injection assembly 17 is arranged on and therapeutic drug monitoring assembly 9 relative bearing
Opposite side support desk track 10 on, mainly include therapeutic drug monitoring minisize pick-up head 52,
Administration needle head 53, electromagnetic valve 54, cooling water jacket 55, Hydraulic pump 56, Stress control and peace
Full valve 57, grug transportation tube 58, grug transportation tube collar nut 59, syringe cavity 60, cooling water return liquid
Mouth 61 (see Fig. 8).Described minisize pick-up head 52 and the blood medicine in therapeutic drug monitoring assembly 9
Concentration monitor minisize pick-up head 51 function is identical, is used for the most here monitoring and record acupuncture treatment position
Situation about putting.Described cooling water jacket 55 uses light screening material to make, and keeps for meeting needs
Uniform temperature or need the medicine requirement of shading.Hydraulic pump 56, Stress control are used with relief valve 57
In the Teat pipette in storing medicine bottle to syringe cavity 60 and is kept or the pressure of regulation syringe cavity 60
Power.Drug injection assembly 17 have equally the base consistent with therapeutic drug monitoring assembly 9,
Mechanical arm and spherical joint, the position of syringe cavity 60 is equivalent to therapeutic drug monitoring assembly 9
The position of mechanical hand head.By therapeutic drug monitoring assembly 9 feedack, drug injection
Assembly 17 accepts the instruction of external computer controller 66 and supplements medicament to rat, regulates blood medicine
Concentration, makes up to requirement of experiment.
Described Worm Wheel System assembly 7 totally two groups, all include controllable motor 64,
Worm screw 65, base worm gear 62 and worm-wheel shaft 63 (see Fig. 9).Worm screw (65) is installed on and props up
In support table support desk track 10, it is dense that base worm gear 62 and worm-wheel shaft 63 are arranged on above-mentioned blood medicine
On degree monitoring assembly base 46 and drug injection assembly 17 base, can drive respectively and regulate blood
Concentration monitoring assembly 9 and drug injection assembly 17 position of 10 on support desk track.
Claims (8)
1. serum level controls a device, including support table body (1), tail constraint
Band (2), column gear transmission assembly (3), tail fixed support (5), Worm Wheel System
Assembly (7), rat fixed station assembly (8), therapeutic drug monitoring assembly (9), drug injection are total
Become (17) and external computer controller (66), it is characterised in that external computer controller (66)
With column gear transmission assembly (3), Worm Wheel System assembly (7), rat fixed station assembly
(8), therapeutic drug monitoring assembly (9), drug injection assembly (17) are connected by electric wire (67)
Realize column gear transmission assembly (3), Worm Wheel System assembly (7), rat fixed station
Assembly (8), therapeutic drug monitoring assembly (9), the control of drug injection assembly (17)；Described
Support table body (1) structure is that centre has rectangular opening (16), rectangular opening (16) both sides desktop
It is provided with support desk support desk track (10) that cross section is T-shaped groove, on rectangular opening (16) inwall
It is provided with the dead eye (15) installing rat fixed station assembly (8), the table of rat tails side
Having tail fixed groove (4) in the middle of face, tail fixed groove (4) has tail to retrain on one side
Locking hole (6), the support of described support table body (1) is by four supports of distribution corner
Table leg (11) forms.
A kind of serum level the most according to claim 1 controls device, its feature
It is that described column gear transmission assembly (3) includes motor, motor driving cog
Wheel, motor mounting bracket and control module, described motor, motor driving cog
Wheel, the unification of motor mounting bracket, control module are just being installed on tail fixed groove (4)
Lower section desk body lower wall surface on, the motor travelling gear of column gear transmission assembly (3) with
Rat fixed station driven gear (20) engagement connects, and external computer controller (66) passes through
Control the control module of this assembly to control the motor of this assembly, by driving rat to fix
Platform driven gear (20), thus realize the axial-rotation of rat fixed station assembly (8), with
Just rat position and attitude is adjusted.
A kind of serum level the most according to claim 1 controls device, its feature
It is that described rat fixed station assembly (8) is arranged on the rectangular opening (16) of support table body (1)
On dead eye (15) on, rat fixed station assembly (8) by rat fixed station body (19),
Restraining (12), tie up lower limb link closely (13), fixed helmet (14), fold pin (18), rat
Fixed station driven gear (20), rat fixed station driven gear shaft (21), rat fixed station support
Roll on table track (22), lifting jack support desk track (23), lifting jack (24), rat fixed station
Superimposed (25), lifting jack drive mechanism (26), the driven fixing axle of rat fixed station (27), solid
Determine helmet installing hole (28) composition, fold pin (18) by rat fixed station body (19) and rat
On fixed station, folding stand (25) is hinged, rat fixed station driven gear (20) and column gear transmission
The motor travelling gear of assembly (3) is engaged transmission；Rat fixed station support desk rail
Road (22) cross section is the groove of T-shaped, lays respectively at rat fixed station body (19) and rat
The both sides of folding stand (25) on fixed station, are used for fixing spud pile (36)；Lifting jack (24)
Folding stand (25) on lifting rat fixed station, for regulating the angle of bend of rat, its trend
Support desk track be exactly described lifting jack support desk track (23), lifting jack drive mechanism
(26) give lifting jack (24) provide power, lifting jack (24) include lift push rod (30),
Sliding axle (31), lifting jack worm screw (32), lifting jack worm screw (32) drives with lifting jack
Mechanism (26) composition Worm and worm-wheel gearing, its power source is lifting jack drive mechanism (26)
In motor, lifting push rod (30) with rat fixed station on folding stand bottom surface (29),
Sliding axle (31) is hinged；Fixed helmet installing hole (28) is positioned on above-mentioned rat fixed station folding
Superimposed (25) head end, is used for installing fixed helmet (14).
A kind of serum level the most according to claim 3 controls device, its feature
It is that described spud pile (36) is by wishbone (33), clamp nut (34) and spud pile
Guide pad (35) forms, and wishbone (33) divaricates and up-thin-low-thick, therefore fork
Dividing and have certain elastic force, this elastic force is by wishbone and rat fixed station support desk track (22) just
Fixing, wishbone (33) has the screw thread coordinated with clamp nut (34), by clamp nut
It is rotated down the work that can reduce wishbone (33) to rat fixed station support desk track (22)
Firmly, whole spud pile (36) is made to be propped up along rat fixed station by spud pile guide pad (35)
Support table track (22) is mobile, restraining (12), tie up lower limb link closely (13) be arranged on above-mentioned solid
Determine in stake (36), be used for fixing rat, restraining (12), tie up lower limb link closely (13) adjacent
The one side of rat uses soft precoat, tie up lower limb link closely (13) include fastening strip (37) and
Fastening strip snap ring (38), has certain between fastening strip snap ring (38) and fastening strip (37)
Frictional force.
A kind of serum level the most according to claim 3 controls device, its feature
It is that described fixed helmet (14) is arranged on fixed helmet installing hole (28) place and by bar
Fixed helmet is connected by part with folding stand (25) on rat fixed station, this fixed helmet (14)
Including pneumostome (39), neck tension band (40) and eyes mouth (41), it is used for fixing rat
Head.
A kind of serum level the most according to claim 1 controls device, its feature
It is that described therapeutic drug monitoring assembly (9) is arranged on above-mentioned support desk support desk track (10)
On, pass including pull-switch (42), syringe needle tube (43), fiber pipe (44), fiber probe
Sensor (45), base (46), mechanical arm (47), spherical joint (48), mechanical hand head
(49), probe-head control module (50) and therapeutic drug monitoring minisize pick-up head (51), described
Pull-switch (42) can realize syringe needle tube (43), fiber pipe (44) and mechanical hand head (49)
Plug connect, it is simple to detection change with maintenance；Described fiber pipe (44), fiber probe pass
Sensor (45) is installed in above-mentioned syringe needle tube (43), is put in big during experiment together with syringe needle tube
In Mus body；Fiber probe sensor (45) is rotatable, and the signal of acquisition is sent to probe control
Molding block (50), passes to external computer controller after probe-head control module processes by signal
(66), blood drug level can the most just be monitored in real time；Described therapeutic drug monitoring minisize pick-up head
(51) it is arranged on above-mentioned mechanical hand head (49), in external computer control (66)
Show high definition enlarged drawing picture on display and record a video.
A kind of serum level the most according to claim 1 controls device, its feature
It is that described drug injection assembly (17) is arranged on relative with therapeutic drug monitoring assembly (9)
On opposite side support desk track (10) in orientation, mainly include drug injection minisize pick-up head
(52), administration needle head (53), electromagnetic valve (54), cooling water jacket (55), Hydraulic pump (56),
Stress control and relief valve (57), grug transportation tube (58), grug transportation tube collar nut (59), note
Emitter chamber (60), cooling water liquid return hole (61), described drug injection minisize pick-up head (52)
It is identical with the therapeutic drug monitoring minisize pick-up head (51) in therapeutic drug monitoring assembly (9),
Described cooling water jacket (55) uses light screening material to make, and wants for meeting the medicine of needs shading
Ask；Hydraulic pump (56), Stress control and relief valve (57) are for by the Teat pipette in storing medicine bottle
To syringe cavity (60) and keep or regulation syringe cavity (60) pressure；Drug injection is total
(17) are become to have the base consistent with therapeutic drug monitoring assembly (9), mechanical arm (47) equally
With spherical joint (48), the position of syringe cavity (60) is equivalent to therapeutic drug monitoring assembly
(9) position of mechanical hand head (49), by therapeutic drug monitoring assembly (9) feedack,
Drug injection assembly (17) accepts the instruction of external computer controller (66) and supplements to rat
Medicament.
A kind of serum level the most according to claim 1 controls device, its feature
It is described Worm Wheel System assembly (7) totally two groups, all includes controllable motor
(64), worm screw (65), base turbine (62) and worm-wheel shaft (63), worm screw (65) peace
It is loaded in support desk support desk track (10), base worm gear (62) and worm-wheel shaft (63) peace
It is contained in base (46) and the end of drug injection assembly (17) of above-mentioned therapeutic drug monitoring assembly
On seat, can drive and regulate therapeutic drug monitoring assembly (9) and drug injection assembly (17) respectively
Position on support desk support desk track (10).
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410835927.7A CN104490488B (en) | 2014-12-30 | 2014-12-30 | A kind of serum level controls device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410835927.7A CN104490488B (en) | 2014-12-30 | 2014-12-30 | A kind of serum level controls device |
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| CN104490488A CN104490488A (en) | 2015-04-08 |
| CN104490488B true CN104490488B (en) | 2016-11-30 |
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| CN105030368B (en) * | 2015-07-16 | 2017-07-07 | 天津医科大学 | Multifunctional small animal operating desk |
| CN106093371B (en) * | 2016-08-16 | 2017-10-03 | 卢丽花 | A kind of operating method of small white mouse experimental monitoring device |
| CN109730798A (en) * | 2019-03-15 | 2019-05-10 | 中国人民解放军陆军军医大学 | Animal Wounds impregnate seawater device |
| CN111345918A (en) * | 2020-03-12 | 2020-06-30 | 谢双 | Medical experimental equipment |
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| CN204521034U (en) * | 2014-12-30 | 2015-08-05 | 中国医科大学附属第一医院 | A kind of serum level control device |
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| CN102846402A (en) * | 2012-08-14 | 2013-01-02 | 润昌机械制造泰州有限公司 | Inclined animal operating table |
| CN202682092U (en) * | 2012-08-18 | 2013-01-23 | 黑龙江中医药大学 | Rat experiment device |
| CN203598068U (en) * | 2013-10-29 | 2014-05-21 | 南方医科大学珠江医院 | Multifunctional experimental animal operating table |
| CN204521034U (en) * | 2014-12-30 | 2015-08-05 | 中国医科大学附属第一医院 | A kind of serum level control device |
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