CN104474363A - 治疗脑震荡的中药 - Google Patents

治疗脑震荡的中药 Download PDF

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CN104474363A
CN104474363A CN201410682892.8A CN201410682892A CN104474363A CN 104474363 A CN104474363 A CN 104474363A CN 201410682892 A CN201410682892 A CN 201410682892A CN 104474363 A CN104474363 A CN 104474363A
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chinese medicine
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cerebral concussion
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刘东升
姚辉
陈述英
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Abstract

本发明涉及中药配方领域，具体地说是一种治疗脑震荡的中药，其特征是以重量份计由如下原料药制成：血通5～11、石菖蒲8～14、红花5～11、延龄草5～11、臭牡丹8～14、蔓荆子5～11、细辛5～11、刺五加6～12、香橼6～12、酸枣仁6～12、薏苡仁5～9、香附8～14、红天葵8～14、桂枝6～12，通草5～8、竹黄4～7，将上述原料药用水浸泡，煎熬后去渣得滤液。本发明具有升清降浊、活血化瘀、调肝养心之功效，对治疗脑震荡引起的短暂性昏迷、近事遗忘以及头痛、恶心和呕吐等症状具有显著的疗效，药材配伍相宜，成本低廉，安全性能高，无任何毒副作用，对脑震荡的治疗能够达到标本兼治。

Description

治疗脑震荡的中药
技术领域
本发明涉及一种中成药制剂，具体地说是一种用于治疗脑震荡的中药。
背景技术
众所周知，脑震荡是指头部遭受外力打击后，即刻发生短暂的脑功能障碍。病理改变无明显变化，发生机理至今仍有许多争论，临床表现为短暂性昏迷、近事遗忘以及头痛、恶心和呕吐等症状，神经系统检查无阳性体征发现，它是最轻的一种脑损伤，经治疗后大多可以治愈，其可以单独发生，也可以与其他颅脑损伤如颅内血肿合并存在。临床表现为意识障碍：程度较轻而时间短暂，可以短至数秒钟或数分钟，但不超过半小时；近事遗忘：清醒后对受伤当时情况及受伤经过不能回忆，但对受伤前的事情能清楚地回忆；此外，还常伴有头痛、头晕、恶心、厌食、呕吐、耳鸣、失眠、畏光、注意力不集中以及反应迟钝等症状，神经系统检查无阳性体征。
目前对治疗脑震荡缺少有效药物，西药的缺点是作用靶点单一，故临床效果并不能尽如人意，所以对于脑震荡症状的病人，只有中药治疗，才能够达到标本兼治的治疗效果，但是现有的中药治疗疗程长，易复发，疗效不太理想，所以临床迫切需要一种针对脑震荡的治疗药物。
发明内容
本发明的目的就是为了克服上述现有的技术不足，提供一种用于治疗脑震荡的中药，具有升清降浊、活血化瘀、调肝养心之功效，对治疗脑震荡引起的短暂性昏迷、近事遗忘以及头痛、恶心和呕吐等症状具有显著的疗效，药材配伍相宜，成本低廉，安全性能高，无任何毒副作用，对脑震荡的治疗能够达到标本兼治。
本发明解决上述技术问题采用的技术方案是：一种治疗脑震荡的中药，其特征是以重量份计由如下原料药制成：血通5～11、石菖蒲8～14、红花5～11、延龄草5～11、臭牡丹8～14、蔓荆子5～11、细辛5～11、刺五加6～12、香橼6～12、酸枣仁6～12、薏苡仁5～9、香附8～14、红天葵8～14、桂枝6～12，通草5～8、竹黄4～7，将上述原料药用水浸泡，煎熬后去渣得滤液。
本发明的有益效果是，具有升清降浊、活血化瘀、调肝养心之功效，对治疗脑震荡引起的短暂性昏迷、近事遗忘以及头痛、恶心和呕吐等症状具有显著的疗效，药材配伍相宜，成本低廉，安全性能高，无任何毒副作用，对脑震荡的治疗能够达到标本兼治。
具体实施方式
下面结合实施例对本发明作进一步的描述：
实施例1：
采用血通、石菖蒲、红花、延龄草、臭牡丹、蔓荆子、细辛、刺五加、香橼、酸枣仁、薏苡仁、香附、红天葵、桂枝、通草、竹黄为原料制备而成，其组分(重量份)每服为血通6、石菖蒲8、红花6、延龄草6、臭牡丹8、蔓荆子6、细辛6、刺五加7、香橼7、酸枣仁8、薏苡仁6、香附9、红天葵9、桂枝8、通草7、竹黄5。取上述16种原料总重量180克混合，用清洁水浸泡1小时，用水量1200ml，武火煎开后，改用文火煎煮，取汁200ml，二煎加水300ml，水煎取汁200ml，两煎混合，再煎浓缩至300ml，真空无菌包装，即得成品制剂。每日一剂分2次口服，每次早晚空腹服150ml。
本发明血通能扩张冠脉和外周血管、降低外周阻力、减速慢心率、减少和降低心肌耗氧量、增加心肌灌注量、增加脑血流量、对心肌和脑缺血有一定改善作用；石菖蒲化湿开胃，开窍豁痰，醒神益智。用于脘痞不饥，噤口下痢，神昏癫痫，健忘耳聋。理气，活血，散风，去湿；红花活血通经，散瘀止痛，有助于治经闭、痛经、恶露不行、胸痹心痛、瘀滞腹痛、胸胁刺痛、跌打损伤、疮疡肿痛疗效。有活血化瘀，散湿去肿的功效，共为君药；延龄草有活血，镇痛，止血，消肿，去风湿的作用；臭牡丹解毒消肿，祛风除湿，平肝潜阳。用于眩晕，痈疽，疔疮，乳痈，痔疮，湿疹，丹毒，风湿痹痛，两味助君为臣药；佐以蔓荆子、细辛，蔓荆子能散风，微寒清热，轻浮上行，主散头面之邪，有祛风止痛之效，用治外感风热，头痛头晕；细辛解表散寒，祛风止痛，通窍，温肺化饮。用于风寒感冒，头痛，牙痛，鼻塞流涕，鼻鼽，鼻渊，风湿痹痛，痰饮喘咳；刺五加用于风湿痹痛，腰膝酸痛，水肿、小便不利；香橼主治胸腹满闷，胁肋胀痛，咳嗽痰多；酸枣仁有宁心安神，养肝，敛汗的功效，主治虚烦不眠，惊悸怔忡，体虚自汗、盗汗；薏苡仁有健脾渗湿，除痹止泻。用于水肿、脚气、小便不利、湿痹拘挛、脾虚泄泻的功效；香附用于肝郁气滞，胸、胁、脘腹胀痛，消化不良，胸脘痞闷，寒疝腹痛；红天葵清热凉血，活血解毒。治暑热高烧，肺热咳嗽，咯血，跌打扭伤，血瘀疼痛；桂枝发汗解肌，温通经脉，助阳化气，平冲降气。用于风寒感冒，脘腹冷痛，血寒经闭，关节痹痛，痰饮，水肿，心悸，奔豚；通草主淋症涩痛，小便不利，水肿，黄疸，湿温病，小便短赤，产后乳少，经闭，带下。用于湿温尿赤，淋病涩痛，水肿尿少，乳汁不下；竹黄具有祛风除湿，活血舒经，止咳的功效。用于风湿痹痛，四肢麻木，小儿百日咳，白带过多，共为使药。
本发明各原料还可按下表所列比例(重量份)混合的实施例来实现，其煎熬程序、口服方法与实施例1相同，其含量如下表所示。
下面结合我院进行的临床试验对本发明作进一步、详细地描述：
1、临床资料：
选择确诊的脑震荡患者100例，其中男性55例，女性45例，年龄33～74岁，平均年龄53.5岁，病程1～5年。
2、治疗方法：
每日一剂分2次口服，每次早晚空腹服150ml，8天为1个疗程，连续服用3个疗程。
3、疗效判定：
(1)治愈：头痛、头晕、恶心、呕吐、心烦等症状完全消失，身体恢复健康。
(2)显效：头痛、头晕、恶心、呕吐、心烦等症状明显好转，身体逐渐恢复。
(3)有效：自觉症状有所好转，偶有生气或过劳后头痛、失眠症状。
(4)无效：通过治疗后症状无减轻或加重
4、结果：
治愈50例，显效34例，有效12例，无效4例，总有效率96％。
典型病例：
丛某，女，39岁。患者骑机动车不幸摔倒，头部着地，神志不清约20分钟，醒后心神恍惚、面色苍白、冷汗出、头痛、头晕、恶心，来诊我院，诊为脑震荡。给予本发明中药制剂，每日一剂分2次口服，每次早晚空腹服150ml，8天为1个疗程，服用1个疗程后，上述症状明显好转，继续服用1个疗程后，痊愈，1年后随访无复发。
孙某，男，45岁。患者与人冲突头部撞到墙上，经医院诊断为重度脑震荡，经过治疗，出院后头脑仍不清醒，便秘，说话含糊，血压偏高等症。服用本发明中药制剂，服用1个疗程后，患者能主动接待客人，便秘消除，服用2个疗程后，说话口齿清晰，血压正常，达到基本痊愈。
胡某，女，49岁。患者曾被木棒击中头部，昏迷15分钟后自行清醒，醒后自感头痛、头晕、恶心，1小时后被送来我院，被确诊为轻度脑震荡，给予本发明中药制剂，服用2个疗程后，自觉症状明显好转，服用3个疗程后，痊愈，半年后随访未复发。

Claims (1)

1.一种治疗脑震荡的中药，其特征在于：以重量份计由如下原料药制成，血通5～11、石菖蒲8～14、红花5～11、延龄草5～11、臭牡丹8～14、蔓荆子5～11、细辛5～11、刺五加6～12、香橼6～12、酸枣仁6～12、薏苡仁5～9、香附8～14、红天葵8～14、桂枝6～12，通草5～8、竹黄4～7，将上述原料药用水浸泡，煎熬后去渣得滤液。
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