CN104436147A - Medicine composition for treating chloasma - Google Patents

Medicine composition for treating chloasma Download PDF

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Publication number
CN104436147A
CN104436147A CN201410843780.6A CN201410843780A CN104436147A CN 104436147 A CN104436147 A CN 104436147A CN 201410843780 A CN201410843780 A CN 201410843780A CN 104436147 A CN104436147 A CN 104436147A
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weight portion
radix
medicine composition
blood
medicine
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钱家美
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/638Ligustrum, e.g. Chinese privet
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/732Chaenomeles, e.g. flowering quince
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738Rosa (rose)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/37Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
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Abstract

The invention relates to a medicine composition for treating chloasma. The medicine composition comprises salvia, papaya, angelica, astragalus, black fungi, pungent oleaster root, privet, liquorice, ophiopogon, pilose antler, dried ginger and roses. The medicine composition has the advantages of fast effect, short treatment period, effective rate and high curative rate, is convenient to use, has no toxic and side effects, and is applicable to various people suffering from chloasma at different degrees.

Description

A kind of pharmaceutical composition for the treatment of yellowish-brown pinta
Technical field
The invention belongs to tcm field, particularly relate to a kind of pharmaceutical composition for the treatment of yellowish-brown pinta.
Background technology
Chloasma is a kind of common dermatosis, commonplace, distribute wide, fall ill in recent years on the rise, that a kind of skin of generally acknowledging both at home and abroad coagulates difficult disease, the numerous patient of grievous injury is physically and mentally healthy and attractive in appearance, the method of current this disease for the treatment of and medicine a lot, but can not reach Preferred effects, and the living and diet of modern people is too meticulous, quantity of motion reduces, or eating and drinking too much at one meal, or overstrain, body metabolism function is failed gradually, cause visceral dysfunction, easily cause the pigmented lesion such as chloasma faciei, freckle.The traditional Chinese medical science is thought, facial colour spot is that blood deficiency is not dissolved in face because of zang-fu differentiation qi and blood disorder; Or because of internal injury caused by excess of seven emotions, stagnation of QI due to depression of the liver, incoordination between the liver and spleen; Or because of improper diet and overtiredness, menoxenia; Or because of the blood system of fire stagnation meridians, ailment said due to cold or exposure is rich outward and caused by sending out.Adopt this kind of disease of western medicine, be mostly outer wiping or vitamins for oral administration, flavonols medicine.Because pathogenesis is more, adopt western medicine effect to differ, also not easily effect a radical cure, some medicine side effect is larger.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind ofly has instant effect, treatment phase short, effective percentage and the high feature of healing, easy to use, nontoxic, a new generation's treatment chloasma medicine compositions of having no side effect.
The pharmaceutical composition of the yellowish-brown pinta for the treatment of provided by the invention, comprises following bulk drugs component and weight portion thereof: Radix Salviae Miltiorrhizae 50-80 weight portion, Fructus Chaenomelis 10-30 weight portion, Radix Angelicae Sinensis 30-50 weight portion, the Radix Astragali 15-45 weight portion, Auricularia 15-45 weight portion, Radix Elaeagni 55-85 weight portion, Fructus Ligustri Lucidi 15-45 weight portion, Radix Glycyrrhizae 5-10 weight portion, Radix Ophiopogonis 20-50 weight portion, Cornu Cervi Pantotrichum 10-20 weight portion, Rhizoma Zingiberis 20-30 weight portion, Flos Rosae Rugosae 10-50 weight portion.
The pharmaceutical composition of the yellowish-brown pinta for the treatment of provided by the invention, more preferably raw material components weight portion is: Radix Salviae Miltiorrhizae 50 weight portion, Fructus Chaenomelis 10 weight portion, Radix Angelicae Sinensis 35 weight portion, the Radix Astragali 20 weight portion, Auricularia 20 weight portion, Radix Elaeagni 60 weight portion, Fructus Ligustri Lucidi 20 weight portion, Radix Glycyrrhizae 5 weight portion, Radix Ophiopogonis 25 weight portion, Cornu Cervi Pantotrichum 10 weight portion, Rhizoma Zingiberis 25 weight portion, Flos Rosae Rugosae 30 weight portion.
In the present invention
Rhizoma Zingiberis: pungent, heat, returns spleen, stomach, the heart, lung meridian.Warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, warming the lung to resolve fluid-retention.
Radix Ophiopogonis: enter cardiopulmonary, stomach is through energy nourishing YIN and moistening the lung, and promote the production of body fluid stomach reinforcing, and clear away heart-fire effect of eliminating the phlegm.
Radix Salviae Miltiorrhizae: enter conscience warp, energy promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, evacuation of pus is subsided a swelling, tranquilizing by nourishing the heart, healthy and strong blood, the effect of conciliation.
Fructus Chaenomelis: have dehumidifying relaxing muscles and tendons and activating QI and blood in the collateral, regulates the effect that meridians stretch.
The Radix Astragali: warm in nature is the key medicine of a QI invigorating, and the functional recovery of lacking of proper care mutually can be made normal.And have cardiotonic.
Radix Angelicae Sinensis: warm in nature, sweet in the mouth is pungent.GUIXIN, liver, spleen channel.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.
Radix Elaeagni: evergreen shrubs, the Radix Elaeagni of this plant.Nature and flavor acid, nontoxic, be in harmonious proportion spleen, dissipating blood stasis removing toxic substances is because there is regulating the liver and spleen to adjust the effect of stomach, tonification the five internal organs.
Fructus Ligustri Lucidi: enter liver, kidney channel the kidney invigorating, strong waist lower limb, controls yin asthenia generating intrinsic heat, effect of order flower tinnitus.
Auricularia: sweet in the mouth, property are flat, return stomach, large intestine channel.There is QI invigorating, lung moistening, supplementing the brain, make light of one's life by commiting suicide, removing heat from blood, hemostasis, astringing intestine to stop diarrhea, invigorate blood circulation, Qiang Zhi, support the effect such as appearance.
Radix Glycyrrhizae: enter the heart, spleen channel, the effect of lung moistening coordinating the actions of various ingredients in a prescription removing toxic substances.
Flos Rosae Rugosae: property is sweet, mildly bitter flavor, temperature.Return liver, spleen channel, have promoting QI circulation for relieving depression, effect of promoting blood circulation and stopping pain.
Cornu Cervi Pantotrichum: kidney invigorating and YANG supporting.
According to the yellowish-brown pinta for the treatment of provided by the invention pharmaceutical composition described in yellowish-brown pinta be caused by damaged by excess of seven emotions according to Chinese medicine, the cause of disease is intricate.Mainly blood or a blood circulation, or endocrine disturbance road causes reason.The obstructed imbalance of QI and blood, by the hepatic and renal YIN deficiency, causes blood not support skin, and SHENGHUANG brown patch, informs that blood is good, the good light of skin and flesh has pool from our ancestors, proves that chloasma and blood and endocrine are closely related.Doctor trained in Western medicine be due to people immune system dysfunction lowly caused by.Really be divide caused reason of must lacking of proper care in liver, this is that medical circle generally acknowledges a fact.The healthy energy of people refers to that each function of organization of the vital organs of the human body is prosperous and reaches.QI and blood is sufficient, equilibrium between yin and yang, an important step on healthy energy lung.The convergence of vessels in the lung, our ancestors just know in one's early years and have separated, and time normal, skin gloss has face.The growth of hair is all by depending on lung qi Wen Zhao.Lung governing qi simultaneously, blood circulation depending on qi flow, demonstrates lung relevant with chloasma.
The blood stored in the liver of speech, to be that blood is logical be linked to cardiopulmonary liver to arteries and veins, and susceptible to anger is sad in liver, because liver is store blood, catharsis endocrine bile and regulating action, return former store blood to be main.Can have one's ideas straightened out in order again, black dull now, night is insomnia, chloasma and liver direct relation, demonstrates and adjusts blood because of the Chinese medicine from liver.
The formula of these crude drug above-mentioned (or claiming Chinese herbal medicine) component composition, all has commercially available.The comprehensive compatibility of prescription, cooperatively interacts as with, synergism, had both played the unique effects that single component medicine has, again one each other, greatly promotes that drug effect improves, and makes cure rate and effective percentage greatly improve, and shortens treatment cycle.
Detailed description of the invention
The present invention's the following example further illustrates the present invention.
EXAMPLE l
By marketable material medicine respectively through selected, remove defective crude drug and impurity is cleaned again, through sterilization treatment crude drug after drying: Radix Salviae Miltiorrhizae 5kg, Fructus Chaenomelis lkg, Radix Angelicae Sinensis 3.5kg, Radix Astragali 2kg, Auricularia 2kg, Radix Elaeagni 6kg, Fructus Ligustri Lucidi 2kg, Radix Glycyrrhizae 0.5kg, Radix Ophiopogonis 2.5kg, Cornu Cervi Pantotrichum lkg, Rhizoma Zingiberis 2.5kg, Flos Rosae Rugosae 3kg mixture is put into infuser device and is soaked in water, the consumption of water is as the criterion to soak powder stock medicine, after covering tightly sealing, ten days are soaked in less than 10 DEG C ventilating and cooling places, take out medicinal liquid, be filtered into pure clear liquid medicine, then in every bag of 200 milliliters of plastic bags, pure clear liquid medicine oral liquid medicine is become with filling apparatus fill after aseptic process, instructions of taking: every twice-daily, each one bag.
Embodiment 2
By each marketable material medicine respectively through selected, remove defective crude drug and impurity, clean the dry crude drug after drying and sterilizing process again: Radix Salviae Miltiorrhizae 65 grams, Fructus Chaenomelis 20 grams, Radix Angelicae Sinensis 40 grams, the Radix Astragali 35 grams, Auricularia 30 grams, Radix Elaeagni 70 grams, Fructus Ligustri Lucidi 40 grams, 8 grams, Radix Glycyrrhizae, Radix Ophiopogonis 40 grams, 15 grams, Cornu Cervi Pantotrichum, Rhizoma Zingiberis 25 grams, Flos Rosae Rugosae 45 grams be placed on common pottery fill with in slow fire boiling 2 hours, leach 300 to 400 milliliters of medicinal liquids, it is oral dose on the one, directly oral, instructions of taking a: twice-daily, each 150 milliliters-200 milliliters.
Embodiment 3
By each following bulk drugs commercially available respectively through selected, remove defective crude drug and impurity is cleaned again, dry in drying plant, carry out the dry crude drug after aseptic process again: Radix Salviae Miltiorrhizae 8kg, Fructus Chaenomelis 3kg, Radix Angelicae Sinensis 5kg, Radix Astragali 4.5kg, Auricularia 4.5kg, Radix Elaeagni 8.5kg, Fructus Ligustri Lucidi 4.5kg, Radix Glycyrrhizae lkg, Radix Ophiopogonis 5kg, Cornu Cervi Pantotrichum 2kg, Rhizoma Zingiberis 3kg, Flos Rosae Rugosae 5kg, according to making an instant medicine material in " whole part " extraction equipment, and fill with in 3-5 grams every bag sealed, sterile bags.Instructions of taking: every day 2 bags, each one bag.

Claims (1)

1. treat a pharmaceutical composition for yellowish-brown pinta, comprise following bulk drugs component and weight portion thereof: Radix Salviae Miltiorrhizae 50-80 weight portion, Fructus Chaenomelis 10-30 weight portion, Radix Angelicae Sinensis 30-50 weight portion, the Radix Astragali 15-45 weight portion, Auricularia 15-45 weight portion, Radix Elaeagni 55-85 weight portion, Fructus Ligustri Lucidi 15-45 weight portion, Radix Glycyrrhizae 5-10 weight portion, Radix Ophiopogonis 20-50 weight portion, Cornu Cervi Pantotrichum 10-20 weight portion, Rhizoma Zingiberis 20-30 weight portion, Flos Rosae Rugosae 10-50 weight portion.
CN201410843780.6A 2014-12-31 2014-12-31 Medicine composition for treating chloasma Pending CN104436147A (en)

Priority Applications (1)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102908530A (en) * 2012-10-16 2013-02-06 周岳松 Oral medicine for treating chloasma and preparation method of same
CN104056222A (en) * 2014-06-16 2014-09-24 程泽莉 Menstruation-regulating beauty tonic pill

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102908530A (en) * 2012-10-16 2013-02-06 周岳松 Oral medicine for treating chloasma and preparation method of same
CN104056222A (en) * 2014-06-16 2014-09-24 程泽莉 Menstruation-regulating beauty tonic pill

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
刘海燕等: ""陈明岭教授治疗黄褐斑临床经验"", 《四川中医》 *
梁勇: "补益肝肾与活血化瘀法治疗黄褐斑200例", 《吉林中医药》 *

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Application publication date: 20150325