CN104435704A - Traditional Chinese medicine tablets for treating takayasu arteritis - Google Patents

Traditional Chinese medicine tablets for treating takayasu arteritis Download PDF

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Publication number
CN104435704A
CN104435704A CN201410626275.6A CN201410626275A CN104435704A CN 104435704 A CN104435704 A CN 104435704A CN 201410626275 A CN201410626275 A CN 201410626275A CN 104435704 A CN104435704 A CN 104435704A
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parts
radix
fructus
preparata
takayasu arteritis
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孙晶伟
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JINAN GAODA INFORMATION TECHNOLOGY Co Ltd
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JINAN GAODA INFORMATION TECHNOLOGY Co Ltd
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    • AHUMAN NECESSITIES
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    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
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    • A61K36/88Liliopsida (monocotyledons)
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    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Abstract

The invention discloses traditional Chinese medicine tablets for treating takayasu arteritis and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine tablets are prepared from the following raw material medicines in parts by weight: 25-30 parts of lysimachia christinae hance, 25-30 parts of oriental wormwood, 20-25 parts of rheum officinale, 20-25 parts of oldenlandia diffusa, 12-18 parts of immature bitter orange, 16-20 parts of radix curcumae, 15-20 parts of peach kernel, 12-18 parts of salvia miltiorrhiza, 12-18 parts of astragalus, 10-15 parts of Chinese yam, 10-15 parts of radix bupleuri, 8-12 parts of honey-fried licorice root, 12-18 parts of poria cocos, 12-16 parts of bighead atractylodes rhizome, 8-12 parts of apricot kernel, 9-15 parts of cassia twig, 10-18 parts of akebiaquinata, 12-18 parts of sweet wormwood, 12-16 parts of red paeony root, 12-18 parts of medicated leaven, 12-18 parts of pinellia ternata and 12-15 parts of malt. The traditional Chinese medicine tablets have the beneficial effects that the tablets have the effects of invigorating the kidney and strengthening Yang, promoting blood circulation to remove blood stasis, improving the symptoms, alleviating pain of patients and reducing the economical burden of the patients and are short in treatment cycle and obvious in effects.

Description

A kind of Chinese medicinal tablet for the treatment of Takayasu arteritis
Technical field
The present invention relates to a kind of medicine for the treatment of Takayasu arteritis, belong to technical field of Chinese medicines, specifically a kind of Chinese medicinal tablet for the treatment of Takayasu arteritis.
Background technology
Takayasu arteritis refers to that aorta and Main Branches and Pulmonic chronic progressive external nonspecific inflammation thereof become.To cause the narrow of different parts or obturation, a few patients because of the middle level of inflammatory destruction arterial wall, and causes arteriectasia or aneurysm.Because the position of pathological changes is different, its clinical manifestation is also different.4 types can be divided into: brachiocephalic artery type according to diseased region; Thoracoabdominal aorta type; Mixed type; Pulmonary artery type.Brachiocephalic artery type symptom: carotid artery and vertebral artery narrowing and obturation, brain ischemia in various degree can be caused, occur dizzy, dizzy, headache, hypomnesis, one-sided or bilateral has stain, visual deterioration, constriction of visual field even blind depending on thing, the unable and masticatory muscles palatine myalgia of masseteric muscle.Thoracoabdominal aorta type: headache, dizziness, nervous can be had with hyperpietic, due to lower limb ischemia, occur unable, send out cool, ache, the symptom such as fatiguability and intermittent claudication.Mixed type has the feature of above-mentioned two types, and belong to Multiple, the most of patients state of an illness is heavier.Pulmonary artery type: above-mentioned 3 types all can merge pulmonary artery and get involved, and in all types of with or between getting involved without pulmonary artery without significant difference.Theory of Chinese medical science is thought, large dynamic inflammation belongs to the traditional Chinese medical science " BI-syndrome involved the blood vessels " scope, and be congenital defect, asthenia of both the spleen and kidney, or congenital imbalance, caused by gas of suffering from a deficiency of the kidney is weak.Insufficiency of kidney-YANG is then yin-cold excess, and blood vessels are met cold and stagnate, the deficiency of vital energy then hematogenous blockage, run slowly, with the passing of time then the venation stasis of blood is stagnant, very then inaccessible obstruct, so that hesitant pulse is as silk or pulsus deletus, treatment should improve symptom with kidney invigorating and YANG supporting, blood circulation promoting and blood stasis dispelling meridianactivating method, contributes to the foundation of Doppler flow mapping.The invention provides a kind of Chinese medicinal tablet for the treatment of Takayasu arteritis, on the basis of the theory of Chinese medicine, the Chinese herbal medicine using Chinese tradition is raw material, through autonomous compatibility, develops, has good therapeutic effect.
Summary of the invention
The present invention is to provide a kind of Chinese medicinal tablet for the treatment of Takayasu arteritis, and the Chinese herbal medicine using Chinese tradition is raw material, meets the theory of Chinese medicine, has good therapeutic effect.
The property of medicine of Chinese herbal medicine selected by the present invention and function cure mainly and are respectively:
Zaocys [nature and flavor] is sweet salty, flat.[function cures mainly] wind-damp dispelling, the meridian dredging.Dispelling the wind and dampness pathogens insensitive impediment, numbness of the skin, bone, tuberculosis of joint, rubella scabies, leprosy, tetanus, poliomyelitis.1. " property of medicine opinion ": " control pyretic toxicity wind, the raw skin ulcer of skin, eyebrow must come off, and Guo itches scabies etc." 2. " Kaibao Bencao)): " main all wind scabies urticarias, scabies, munbness, all wind of insensitive impediment." 3. " detailed outline ": " merit and Agkistrodon with and property is apt to nontoxic." 4. " medical center bun is wanted ": " YIN nourishing improving eyesight."
Fructus Foeniculi [nature and flavor] is pungent, temperature.[return through] returns liver,kidney,spleen, stomach warp.[function cures mainly] dispersing cold for relieving pain, regulating qi-flowing for harmonizing stomach.For colic of cold type stomachache, the testis swelling and hanging down of either of the testes, dysmenorrhea, few abdomen cold type of pain, abdominal distention, lack of appetite and vomiting, hydrocele of testis.Salt Fructus Foeniculi warming the kidney dispersing cold for relieving pain.For colic of cold type stomachache, the testis swelling and hanging down of either of the testes, through cold stomachache.
Radix Aconiti Lateralis Preparata: [nature and flavor] are pungent, sweet is warm greatly; Poisonous.[return through] GUIXIN, kidney, spleen channel.[function cures mainly] recuperating depleted YANG and rescuing the patient from collapse, mends fire supporing yang, by wind-cold damp pathogen.For YANG-depletion collapse, cold extremities faint pulse, sexual impotence, cold womb, trusted subordinate's cold type of pain, deficiency and coldness is vomited and diarrhoea, YIN-cold edema, yang deficiency diseases caused by exogenous pathogenic factor, arthralgia due to cold-dampnes.
Rhizoma Polygonati [nature and flavor] is sweet, flat.[return through] returns spleen, lung, kidney channel.[function cures mainly] boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying.For weakness of the spleen and stomach, fatigue and asthenia, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, asthenia of essence and blood, interior-heat is quenched one's thirst.
Ramulus Cinnamomi: [nature and flavor] acrid, sweet, warm.[return through] GUIXIN, lung, urinary bladder channel.[function cures mainly] diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.For anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Radix Clematidis [nature and flavor] is pungent, salty, temperature.[return through] returns urinary bladder channel.[function cures mainly] expelling wind and removing dampness, removing obstruction in the collateral to relieve pain.For rheumatic arthralgia, numb limbs and tense tendons, the contracture of muscle arteries and veins, joint stuffiness, bone is choked with sobs larynx.
Radix Aconiti [nature and flavor] is pungent, heat, poisonous.[return through] 1. " key medicine divides agent ": " enter thigh, the gate of vitality two warp." 2. " book on Chinese herbal medicine brief points ": " the moon, shaoyin channel of fainting of starting with." warming the meridian, pain relieving, controls anemofrigid-damp arthralgia, severe and migratory arthralgia pain, spasm of the limbs, and hemiplegia, wind syndrome of head is had a headache, trusted subordinate's cold type of pain, carbuncle of yin nature toxic swelling for [function cures mainly] dispelling cold and dampness, loose ailment said due to cold or exposure.1. " pearl sac ": " cold removing wet wind numbness, arthralgia due to stagnation of blood." 2. Li Gao: " eliminating cold-damp, passes through, loose ailment said due to cold or exposure, broken all accumulation of pathogenic cold poison.It is not enough that " 3. Wang Haogu: " mends the gate of vitality, and liver-wind is empty." 4. " Wang Shi studies carefully former side ": " property is gently dredged, and warming the spleen removes wind." 5. " detailed outline ": " is supporing yang moves back the moon, and merit is slightly slow with Radix Aconiti Lateralis Preparata."
Radix Rehmanniae Preparata [nature and flavor] is sweet, tepor.[return through] returns liver, kidney channel.[function cures mainly] nourishing YIN and supplementing blood, beneficial essence fills out marrow.For the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, night sweat is passed out semen, and interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, and metrostaxis is dizzy, tinnitus, early whitening of beard and hair.
Caulis Spatholobi meridian distribution of property and flavor: bitter, sweet, temperature.Return liver, kidney channel.Function cures mainly: enrich blood, and invigorates blood circulation, dredging collateral.For menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.
Radix Glycyrrhizae Preparata: [nature and flavor] are sweet is flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Scolopendra [nature and flavor] is pungent, temperature; Poisonous.[return through] returns Liver Channel.[function cures mainly] endogenous wind stopping spasmolytic, merit poison eliminating stagnation, removing obstruction in the collateral to relieve pain.For infantile convulsion, tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, skin infection, scrofula, venom.
The Radix Angelicae Dahuricae [nature and flavor] is pungent, temperature.[return through] returns stomach, large intestine, lung meridian.[function cures mainly] loose wind dehumidifying, understand things pain-stopping, detumescence and apocenosis.For headache due to common cold, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea, skin infection swells and ache.
Herba Epimedii [nature and flavor] acrid, sweet, warm.[return through] returns liver, kidney channel.[function cures mainly] kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.For impotence and seminal emission, muscles and bones flaccidity is soft, rheumatic arthralgia, numbness contracture; Climacteric hypertension.
Radix Morindae Officinalis [nature and flavor] is sweet, pungent, tepor.[return through] returns kidney, Liver Channel.[function cures mainly] kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.For impotence and seminal emission, cold womb is infertile, menoxenia, and few abdomen cold type of pain, rheumatic arthralgia, muscles and bones flaccidity is soft.
Cortex Moutan [nature and flavor] is bitter, pungent, is slightly cold.[return through] GUIXIN, liver, kidney channel.[function cures mainly] clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.For maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, amenorrhea dysmenorrhea, carbuncle sore tumefacting virus, falls and flutters the pain of injury.
Fructus Corni [nature and flavor] is sour, puckery, tepor.[return through] returns liver, kidney channel.[function cures mainly] liver and kidney tonifying, essence astringing and desertion stemming.For vertigo and tinnitus, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, bleeding not during menses, profuse sweating is collapsed.Interior-heat is quenched one's thirst.
Fructus Mori [nature and flavor] is sweet, sour, cold.[return through] GUIXIN, liver, kidney channel.[function cures mainly] to be enriched blood YIN nourishing, is promoted the production of body fluid and moisturize.For vertigo and tinnitus, palpitation and insomnia, early whitening of beard and hair, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, blood deficiency and constipation.
Fructus Lycii [nature and flavor] is sweet, flat.[return through] returns liver, kidney channel.[function cures mainly] nourishing the liver and kidney, replenishing vital essence to improve eyesight.For asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, and blurred vision is failed to understand.
Rhizoma Curculiginis [nature and flavor] is pungent, heat; Poisonous.[return through] returns kidney,liver,spleen warp.[function cures mainly] kidney-replenishing, bone and muscle strengthening, dispelling cold and dampness.For sexual impotence cold sperm, muscles and bones flaccidity is soft, the cold numbness of waist knee joint, yang deficiency cold diarrhea.
Os Draconis [meridian distribution of property and flavor] are sweet, puckery, flat.GUIXIN, liver, kidney channel.Function cures mainly: infantile convulsion is demented, and palpitation with a distress feeling is forgetful, insomnia and dreamful sleep, spontaneous sweating, and seminal emission stranguria with turbid discharge, tell nosebleed and have blood in stool, bleeding not during menses, dysentery proctoptosis, ulcer does not close up for a long time.Os Draconis tranquillizing the mind by relieving convulsion, arresting sweating controlling nocturnal emission with astringent drugs, hemostasis astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing." not Lu " be recorded: Os Draconis treat trusted subordinate's stuffy sensation with restlessness, and extremity flaccidity is withered, sweating, and night is sleeping, and from frightened, be enraged, latent pathogen must not be panted under the heart, cellulitis in acute appendicitis, the erosion of the vulva, hidroschesis, urine reducing, hematuria, supports spirit, determines soul.An Wuzang.
Concha Ostreae [nature and flavor] is salty, is slightly cold.[return through] returns liver, gallbladder, kidney channel.[function cures mainly] tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving.For insomnia of palpitating with fear, vertigo and tinnitus, scrofula sucutaneous nodule, lump in the abdomen mass in the abdomen.Concha Ostreae (calcined) convergence is astringent or styptic treatment for spontaneous sweating.For spontaneous sweating, seminal emission metrorrhagia and leukorrhagia, stomachache acid regurgitation.
Radix Codonopsis [nature and flavor] is sweet, flat.[return through] returns spleen, lung meridian.[function cures mainly] invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst.
The Radix Astragali [nature and flavor] is sweet, temperature.[return through] returns lung, spleen channel.[function cures mainly] invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
The invention provides a kind of Chinese medicinal tablet for the treatment of Takayasu arteritis, be made up of the crude drug of following weight proportion:
Zaocys 20-25 part, Fructus Foeniculi 15-20 part, Radix Aconiti Lateralis Preparata 10-15 part, Rhizoma Polygonati 15-20 part, Ramulus Cinnamomi 12-18 part, Radix Clematidis 18-25 part, Radix Aconiti 12-18 part, Radix Rehmanniae Preparata 25-30 part, Caulis Spatholobi 25-30 part, Radix Glycyrrhizae Preparata 8-12 part, Scolopendra 5-10 part, Radix Angelicae Dahuricae 12-18 part, Herba Epimedii 10-15 part, Radix Morindae Officinalis 16-20 part, Cortex Moutan 12-16 part, Fructus Corni 12-16 part, Fructus Mori 16-20 part, Fructus Lycii 15-20 part, Os Draconis 12-16 part, Concha Ostreae 10-15 part, Radix Codonopsis 15-19 part, Radix Astragali 15-19 part;
Described a kind of preparation method for the treatment of the Chinese medicinal tablet of Takayasu arteritis, detailed process is:
Radix Aconiti is concocted in flakes in advance, Radix Aconiti in the process of preparing Chinese medicine: Radix Glycyrrhizae Preparata: Semen sojae atricolor weight ratio is 90:5:8; Scolopendra is concocted in advance, takes Radix Aconiti and Scolopendra and other medical materials after concocting in proportion, the clean post-dryings of other medical materials, water content is less than 3%, and whole medical material grinds, and crosses No. 6 medicine sieves, No. 6 medicine sieves crossed by adjuvant, medicated powder first mixes in a small amount with adjuvant, repeatedly mixes, strengthens combined amount gradually, repeatedly sieve 2-4 time, enter tabletting machine, it is qualified to detect, packaging.
Described a kind of Chinese medicinal tablet for the treatment of Takayasu arteritis, be made up of the crude drug of following weight proportion:
Zaocys 21-24 part, Fructus Foeniculi 16-19 part, Radix Aconiti Lateralis Preparata 11-14 part, Rhizoma Polygonati 16-19 part, Ramulus Cinnamomi 13-17 part, Radix Clematidis 19-24 part, Radix Aconiti 13-17 part, Radix Rehmanniae Preparata 26-29 part, Caulis Spatholobi 26-29 part, Radix Glycyrrhizae Preparata 9-11 part, Scolopendra 6-9 part, Radix Angelicae Dahuricae 13-17 part, Herba Epimedii 11-14 part, Radix Morindae Officinalis 17-19 part, Cortex Moutan 13-15 part, Fructus Corni 13-15 part, Fructus Mori 17-19 part, Fructus Lycii 16-19 part, Os Draconis 13-15 part, Concha Ostreae 11-14 part, Radix Codonopsis 16-18 part, Radix Astragali 16-18 part.
Described a kind of Chinese medicinal tablet for the treatment of Takayasu arteritis, be made up of the crude drug of following weight proportion:
Zaocys 22 parts, Fructus Foeniculi 17 parts, Radix Aconiti Lateralis Preparata 12 parts, Rhizoma Polygonati 17 parts, Ramulus Cinnamomi 15 parts, Radix Clematidis 23 parts, Radix Aconiti 15 parts, Radix Rehmanniae Preparata 28 parts, Caulis Spatholobi 28 parts, Radix Glycyrrhizae Preparata 10 parts, Scolopendra 8 parts, the Radix Angelicae Dahuricae 16 parts, Herba Epimedii 12 parts, Radix Morindae Officinalis 18 parts, Cortex Moutan 14 parts, Fructus Corni 14 parts, 18 parts, Fructus Mori, Fructus Lycii 18 parts, Os Draconis 14 parts, Concha Ostreae 13 parts, Radix Codonopsis 17 parts, the Radix Astragali 17 parts.
Usefulness of the present invention: treatment kidney invigorating and YANG supporting, blood circulation promoting and blood stasis dispelling meridianactivating method improve symptom, the Radix Aconiti of concocting in side, Radix Aconiti Lateralis Preparata, Herba Epimedii, Radix Morindae Officinalis kidney invigorating and YANG supporting are passed through blood vessels, and Radix Rehmanniae Preparata, Cortex Moutan Rhizoma Polygonati, Ramulus Cinnamomi, Radix Clematidis, Caulis Spatholobi are enriched blood active promoting blood circulation; Zaocys, Scolopendra are walked to alter and are searched wind and promote blood circulation, and strengthen unobstructed vessel, get through obstruction, Concha Ostreae tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving, in addition Fructus Corni, Os Draconis tranquillizing the mind by relieving convulsion, liver and kidney tonifying, arresting sweating controlling nocturnal emission with astringent drugs, prevents letting out of YANG QI, be aided with Fructus Foeniculi, angelica dahurica powder wind dehumidifies, understand things pain-stopping, regulating qi-flowing for harmonizing stomach; Fructus Mori is enriched blood YIN nourishing, promotes the production of body fluid and moisturizes; Fructus Lycii nourishing the liver and kidney, replenishing vital essence to improve eyesight; The Radix Astragali, Radix Codonopsis coordinate invigorating the spleen and replenishing QI, diuresis poison holding, spleen invigorating lung benefiting; Radix Glycyrrhizae Preparata tonify deficiency and medicine, the dry property of pharmacy, all medicines coordinate kidney invigorating and YANG supporting, blood circulation promoting and blood stasis dispelling is promoted blood circulation, and takes into account the object that other reach treatment.In addition, patient is confident to take medicine lastingly, just can receive good effect.
Detailed description of the invention
Embodiment 1
Treat a Chinese medicinal tablet for Takayasu arteritis, be made up of the crude drug of following weight proportion:
Zaocys 20 parts, Fructus Foeniculi 15 parts, Radix Aconiti Lateralis Preparata 10 parts, Rhizoma Polygonati 15 parts, Ramulus Cinnamomi 12 parts, Radix Clematidis 18 parts, Radix Aconiti 12 parts, Radix Rehmanniae Preparata 25 parts, Caulis Spatholobi 25 parts, Radix Glycyrrhizae Preparata 8 parts, Scolopendra 5 parts, the Radix Angelicae Dahuricae 12 parts, Herba Epimedii 10 parts, Radix Morindae Officinalis 16 parts, Cortex Moutan 12 parts, Fructus Corni 12 parts, 16 parts, Fructus Mori, Fructus Lycii 15 parts, Os Draconis 12 parts, Concha Ostreae 10 parts, Radix Codonopsis 15 parts, the Radix Astragali 15 parts;
Described a kind of preparation method for the treatment of the Chinese medicinal tablet of Takayasu arteritis, detailed process is:
Radix Aconiti is concocted in flakes in advance, Radix Aconiti in the process of preparing Chinese medicine: Radix Glycyrrhizae Preparata: Semen sojae atricolor weight ratio is 90:5:8; Scolopendra is concocted in advance, takes Radix Aconiti and Scolopendra and other medical materials after concocting in proportion, the clean post-dryings of other medical materials, water content is less than 3%, and whole medical material grinds, and crosses No. 6 medicine sieves, No. 6 medicine sieves crossed by adjuvant, medicated powder first mixes in a small amount with adjuvant, repeatedly mixes, strengthens combined amount gradually, repeatedly sieve 2-4 time, enter tabletting machine, it is qualified to detect, packaging.
Embodiment 2
Treat a Chinese medicinal tablet for Takayasu arteritis, be made up of the crude drug of following weight proportion:
Zaocys 21 parts, Fructus Foeniculi 16 parts, Radix Aconiti Lateralis Preparata 11 parts, Rhizoma Polygonati 16 parts, Ramulus Cinnamomi 13 parts, Radix Clematidis 19 parts, Radix Aconiti 13 parts, Radix Rehmanniae Preparata 26 parts, Caulis Spatholobi 26 parts, Radix Glycyrrhizae Preparata 9 parts, Scolopendra 6 parts, the Radix Angelicae Dahuricae 13 parts, Herba Epimedii 11 parts, Radix Morindae Officinalis 17 parts, Cortex Moutan 13 parts, Fructus Corni 13 parts, 17 parts, Fructus Mori, Fructus Lycii 16 parts, Os Draconis 13 parts, Concha Ostreae 11 parts, Radix Codonopsis 16 parts, the Radix Astragali 16 parts.
Preparation method is with embodiment 1
Embodiment 3
Treat a Chinese medicinal tablet for Takayasu arteritis, be made up of the crude drug of following weight proportion:
Zaocys 22 parts, Fructus Foeniculi 17 parts, Radix Aconiti Lateralis Preparata 12 parts, Rhizoma Polygonati 17 parts, Ramulus Cinnamomi 15 parts, Radix Clematidis 23 parts, Radix Aconiti 14 parts, Radix Rehmanniae Preparata 28 parts, Caulis Spatholobi 28 parts, Radix Glycyrrhizae Preparata 10 parts, Scolopendra 8 parts, the Radix Angelicae Dahuricae 16 parts, Herba Epimedii 12 parts, Radix Morindae Officinalis 18 parts, Cortex Moutan 14 parts, Fructus Corni 14 parts, 18 parts, Fructus Mori, Fructus Lycii 18 parts, Os Draconis 14 parts, Concha Ostreae 13 parts, Radix Codonopsis 17 parts, the Radix Astragali 17 parts.
Preparation method is with embodiment 1
Embodiment 4
Treat a Chinese medicinal tablet for Takayasu arteritis, be made up of the crude drug of following weight proportion:
Zaocys 24 parts, Fructus Foeniculi 19 parts, Radix Aconiti Lateralis Preparata 14 parts, Rhizoma Polygonati 19 parts, Ramulus Cinnamomi 17 parts, Radix Clematidis 24 parts, Radix Aconiti 17 parts, Radix Rehmanniae Preparata 29 parts, Caulis Spatholobi 29 parts, Radix Glycyrrhizae Preparata 11 parts, Scolopendra 9 parts, the Radix Angelicae Dahuricae 17 parts, Herba Epimedii 14 parts, Radix Morindae Officinalis 19 parts, Cortex Moutan 15 parts, Fructus Corni 15 parts, 19 parts, Fructus Mori, Fructus Lycii 19 parts, Os Draconis 15 parts, Concha Ostreae 14 parts, Radix Codonopsis 18 parts, the Radix Astragali 18 parts.
Preparation method is with embodiment 1
Embodiment 5
Treat a Chinese medicinal tablet for Takayasu arteritis, be made up of the crude drug of following weight proportion:
Zaocys 25 parts, Fructus Foeniculi 20 parts, Radix Aconiti Lateralis Preparata 15 parts, Rhizoma Polygonati 20 parts, Ramulus Cinnamomi 18 parts, Radix Clematidis 25 parts, Radix Aconiti 18 parts, Radix Rehmanniae Preparata 30 parts, Caulis Spatholobi 30 parts, Radix Glycyrrhizae Preparata 12 parts, Scolopendra 10 parts, the Radix Angelicae Dahuricae 18 parts, Herba Epimedii 15 parts, Radix Morindae Officinalis 20 parts, Cortex Moutan 16 parts, Fructus Corni 16 parts, 20 parts, Fructus Mori, Fructus Lycii 20 parts, Os Draconis 16 parts, Concha Ostreae 15 parts, Radix Codonopsis 19 parts, the Radix Astragali 19 parts.
Preparation method is with embodiment 1
Using method of the present invention: each 3-7 sheet, every day 2-5 time; Or follow the doctor's advice.Avoid eating anything raw or cold.
Curative effect:
Choose hospital outpatient and be in hospital in patient 500 example of Takayasu arteritis, treatment 2-6 month, all effectively, is almost recovered, referring to table 1.
Efficacy determination: adopt 4 grade standards
Recovery from illness symptom improvement rate >=95%;
Effective symptom improvement rate < 95%, >=60%;
Effective symptom improvement rate < 60%, >=20%;
Invalid symptom improvement rate < 20%;
Table 1
Recovery from illness number (routine %) Effective number (routine %) Efficiently individual quantity (routine %) Invalid number (routine %) Total effective rate (%)
Treat latter 2 months 252(50.4) 148(29.6) 51(10.2) 49(9.8) 91.2
Treat latter 3 months 320 (64.0) 118(23.6) 22(4.4) 40(8.0) 92
Treat latter 4 months 413 (82.6) 41(8.2) 14(2.8) 32(6.4) 93.7
Treat latter 5 months 458(95.6) 20(4.0) 2(0.4) 20(4.0) 96
Treat latter 6 months 485(97.0) 10(2.0) 5(1.0) 0(0) 100
After treating 2-6 month as can be seen from Table 1, the cure rate of 500 patients reaches 97.0%, and total effective rate is 100%, and in treatment after 4 months, the cure rate of patient just reaches 82.6%, total effective rate is 93.7%, illustrate that the Chinese medicinal tablet that the present invention treats Takayasu arteritis has good therapeutic effect, and treatment cycle is shorter, alleviate on patient body painful, reduce patient economy burden, do not worry postoperative complication, and take the toleration of Western medicine.
Case 1 * *, sex: man.Age: 65 years old.Cardinal symptom: neck arteries radiography, both arms tremulous pulse all has obvious stenosis, and inaccessible, occur dizzy, dizzy, headache, hypomnesis, one-sided or bilateral has stain, visual deterioration depending on thing, and hospital is diagnosed as Takayasu arteritis.Take embodiment 1 formula tablet, every day 3 times, each 6,3 months effective, within 5 months, cures, without other untoward reaction.
Case 2 Lee * *, sex: female.Age: 30 years old.Cardinal symptom: headache, pain under clavicle, color ultrasound, neck breast abdomen strengthening CT, has a blood test, and inaccessible under clavicle, hospital is diagnosed as Takayasu arteritis.Take embodiment 2 formula tablet, every day 2 times, each 6,2 months effective, within 3 months, cures, without other untoward reaction.
Case 3 *, sex: man.Age: 53 years old.Cardinal symptom: biochemical analysis is normal, angiography: left common carotid artery is inaccessible, and left clavicle does not develop, and abdomen master pulse is narrow, and hospital is diagnosed as Takayasu arteritis.Take embodiment 3 formula tablet, every day 4 times, each 4,1 month effective, within 2 months, cures, without other untoward reaction.
Case 4 Feng * *, sex: man.45 years old age.Cardinal symptom: upper limb ischemia occurs that both upper extremities is unable, sends out cool, aches, numbness even amyotrophy, side Subclavian artery occlusion, cervical region or supraclavicular part can hear the above systole vascular murmur of secondary, and minority is with trembling, and hospital is diagnosed as Takayasu arteritis.Take embodiment 4 formula tablet, every day 3 times, each 3,1 month effective, within 3 months, cures, without other untoward reaction.
Case 5 king *, sex: female.Age: 25 years old.Cardinal symptom: carotid artery, radial artery, brachial dance weaken or disappear, dizzy, dizzy, headache, hypomnesis, one-sided or bilateral has stain, visual deterioration depending on thing, and hospital is diagnosed as Takayasu arteritis.Take embodiment 5 formula tablet, every day 5 times, each 3,3 months effective, within 5 months, cures, without other untoward reaction.
Case 6 poplar *, sex: man.Age: 35 years old.Cardinal symptom: cervical region or supraclavicular part can hear the above systole vascular murmur of secondary, minority with trembling, unable, send out cool, ache, fatiguability and intermittent claudication, merge stenosis of pulmonary artery person, then occur having palpitation, breathing hard, hospital is diagnosed as Takayasu arteritis.Take embodiment 3 formula tablet, every day 3 times, each 4,1 month effective, within 2 months, cures, without other untoward reaction.
Case 7 Zhao *, sex: female, 50 years old age.Cardinal symptom: cardiopalmus, breathe hard more, diastolic pressure obviously raises, and renal artery stenosis is serious, descending thoracic aorta Serious Stenosis, and bilateral renal arteries is narrow, and shrink and the two phase vascular noise of diastole, hospital is diagnosed as Takayasu arteritis.Take embodiment 4 formula tablet, every day 5 times, each 7,3 months effective, within 6 months, cures, without other untoward reaction.

Claims (3)

1. treat a Chinese medicinal tablet for Takayasu arteritis, be made up of the crude drug of following weight proportion:
Zaocys 20-25 part, Fructus Foeniculi 15-20 part, Radix Aconiti Lateralis Preparata 10-15 part, Rhizoma Polygonati 15-20 part, Ramulus Cinnamomi 12-18 part, Radix Clematidis 18-25 part, Radix Aconiti 12-18 part, Radix Rehmanniae Preparata 25-30 part, Caulis Spatholobi 25-30 part, Radix Glycyrrhizae Preparata 8-12 part, Scolopendra 5-10 part, Radix Angelicae Dahuricae 12-18 part, Herba Epimedii 10-15 part, Radix Morindae Officinalis 16-20 part, Cortex Moutan 12-16 part, Fructus Corni 12-16 part, Fructus Mori 16-20 part, Fructus Lycii 15-20 part, Os Draconis 12-16 part, Concha Ostreae 10-15 part, Radix Codonopsis 15-19 part, Radix Astragali 15-19 part;
Described a kind of preparation method for the treatment of the Chinese medicinal tablet of Takayasu arteritis, detailed process is:
Radix Aconiti is concocted in flakes in advance, Radix Aconiti in the process of preparing Chinese medicine: Radix Glycyrrhizae Preparata: Semen sojae atricolor weight ratio is 90:5:8; Scolopendra is concocted in advance, takes Radix Aconiti and Scolopendra and other medical materials after concocting in proportion, the clean post-dryings of other medical materials, water content is less than 3%, and whole medical material grinds, and crosses No. 6 medicine sieves, No. 6 medicine sieves crossed by adjuvant, medicated powder first mixes in a small amount with adjuvant, repeatedly mixes, strengthens combined amount gradually, repeatedly sieve 2-4 time, enter tabletting machine, it is qualified to detect, packaging.
2. a kind of Chinese medicinal tablet for the treatment of Takayasu arteritis according to claim 1, be made up of the crude drug of following weight proportion:
Zaocys 21-24 part, Fructus Foeniculi 16-19 part, Radix Aconiti Lateralis Preparata 11-14 part, Rhizoma Polygonati 16-19 part, Ramulus Cinnamomi 13-17 part, Radix Clematidis 19-24 part, Radix Aconiti 13-17 part, Radix Rehmanniae Preparata 26-29 part, Caulis Spatholobi 26-29 part, Radix Glycyrrhizae Preparata 9-11 part, Scolopendra 6-9 part, Radix Angelicae Dahuricae 13-17 part, Herba Epimedii 11-14 part, Radix Morindae Officinalis 17-19 part, Cortex Moutan 13-15 part, Fructus Corni 13-15 part, Fructus Mori 17-19 part, Fructus Lycii 16-19 part, Os Draconis 13-15 part, Concha Ostreae 11-14 part, Radix Codonopsis 16-18 part, Radix Astragali 16-18 part.
3. a kind of Chinese medicinal tablet for the treatment of Takayasu arteritis according to claim 1, be made up of the crude drug of following weight proportion:
Zaocys 22 parts, Fructus Foeniculi 17 parts, Radix Aconiti Lateralis Preparata 12 parts, Rhizoma Polygonati 17 parts, Ramulus Cinnamomi 15 parts, Radix Clematidis 23 parts, Radix Aconiti 15 parts, Radix Rehmanniae Preparata 28 parts, Caulis Spatholobi 28 parts, Radix Glycyrrhizae Preparata 10 parts, Scolopendra 8 parts, the Radix Angelicae Dahuricae 16 parts, Herba Epimedii 12 parts, Radix Morindae Officinalis 18 parts, Cortex Moutan 14 parts, Fructus Corni 14 parts, 18 parts, Fructus Mori, Fructus Lycii 18 parts, Os Draconis 14 parts, Concha Ostreae 13 parts, Radix Codonopsis 17 parts, the Radix Astragali 17 parts.
CN201410626275.6A 2014-11-10 2014-11-10 Traditional Chinese medicine tablets for treating takayasu arteritis Pending CN104435704A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106266594A (en) * 2016-08-23 2017-01-04 万龙 A kind of Chinese medicine preparation for gerontal patient's liver-kidney Yin deficiency type giant cell arteritis

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1369297A (en) * 2002-03-15 2002-09-18 刘凤义 'Sishen Tongmai' mixture and its preparing process
CN101234189A (en) * 2008-02-23 2008-08-06 彭青山 Chinese medicine composition for preventing and treating cardiovascular inflammation (toxin)

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1369297A (en) * 2002-03-15 2002-09-18 刘凤义 'Sishen Tongmai' mixture and its preparing process
CN101234189A (en) * 2008-02-23 2008-08-06 彭青山 Chinese medicine composition for preventing and treating cardiovascular inflammation (toxin)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106266594A (en) * 2016-08-23 2017-01-04 万龙 A kind of Chinese medicine preparation for gerontal patient's liver-kidney Yin deficiency type giant cell arteritis

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