CN104434227A - Once-reciprocating self-locking oral cell sampling and storing device - Google Patents
Once-reciprocating self-locking oral cell sampling and storing device Download PDFInfo
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- CN104434227A CN104434227A CN201310427995.5A CN201310427995A CN104434227A CN 104434227 A CN104434227 A CN 104434227A CN 201310427995 A CN201310427995 A CN 201310427995A CN 104434227 A CN104434227 A CN 104434227A
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- push rod
- filter paper
- spatula
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Abstract
The invention discloses a once-reciprocating self-locking oral cell sampling and storing device. The once-reciprocating self-locking oral cell sampling and storing device comprises a flat plastic sleeve, a passage capable of storing a push rod and a tongue depressor is arranged in the sleeve, the front end, the rear end and the top end of the sleeve are provided with windows communicated with the passage, the push rod and the tongue depressor are inserted in the passage, filter paper is fixed at the front end of the push rod, the tongue depressor is arranged below the push rod and the filter paper, and the end of the tongue depressor distant from the filter paper is provided with a self-locking mechanism. The principle includes that the push rod is pushed forwards for the first time, the filter paper and the tongue depressor below the filter paper are pushed out together, and a user can hold the sleeve to sample the oral cells by the filter paper. The push rod is pushed back with slight force, the tongue depressor is self-locked in the plastic sleeve, the push rod is pushed forwards again and at this time, the filter paper can be pushed out. The once-reciprocating self-locking oral cell sampling and storing device is simple to operate, and examination materials are not easy to pollute; the once-reciprocating self-locking oral cell sampling and storing device is applicable to a machine or a manual perforating sampling, direct augmentation without DNA extraction can be realized, establishment efficiency in a DNA database is improved, and DNA examination cost is reduced.
Description
Technical field
The present invention relates to the collection of Stomatocyte and keeping technical field, particularly one once comes and goes self-locking buccal cell collection and save set.
Background technology
Taking mouth desquamated cells to carry out DNA inspection is a kind of non-intervention, no pain, AT method, simple to operate, without the need to sterilization, and does not transfuse blood in the recent period by client or accepts the impact of simplified marrow transplanting.More and more unit utilize extraction have the mouth desquamated cells of the personnel under detention of criminal record and suspect to carry out forensic dna inspection and set up DNA data base both at home and abroad at present.Tradition gathers the common medical cotton stick of the many uses of buccal swab, is not suitable for the method sampling adopting punching.The manual clip sampling of operator, the randomness of amount is comparatively large, and in order to not affect DNA detection analysis below, often needing to use has the paramagnetic particle method of sxemiquantitative Isolation and purification effect to carry out DNA extraction to DNA, causes the cost setting up DNA data base to remain high.
At present just at the oral cavity DNA harvester that some units promote, first adopt sponge stick, harvester etc. to gather mouth desquamated cells, then transfer in a kind of filter paper card and preserve.By sampling to filter paper card there being the position of mouth desquamated cells carry out punching, the direct amplification technique of DNA that then application developed recently gets up carries out pcr amplification, improves the efficiency of forensic dna inspection.But the collection of this oral cavity DNA harvester mouth desquamated cells is separated with preservation, and step is more, complex operation, and sample is easily contaminated.
In sum, current buccal cell collection method or be not suitable for adopt punching method sampling, be difficult to realize the hands-free DNA of getting and directly increase; Or buccal cell collection is separated with preservation, step is more, complex operation, and sample is easily contaminated.
Summary of the invention
Patent of the present invention technical problem to be solved be to provide a kind of simple, convenient machine or manual punch sampling, sample not easily contaminated, be applicable to once round self-locking buccal cell collection and save set that hands-free cut-off connects amplification.
For solving the problems of the technologies described above, the technical solution used in the present invention is: a flat bar plastic sleeve, the passage that can hold push rod and spatula is provided with in sleeve, the front end window A of passage releases flexibly for push rod and spatula, rear end window B is in order to unlock, top window C slides for push rod assembling and push button, push rod and spatula is inserted with in described passage, filter paper is fixed with in the front end of push rod, a spatula is provided with below push rod and filter paper, just use during spatula sampling, spatula is provided with a self-locking mechanism away from filter paper end, after having sampled, spatula can be lockable and not re-use in sleeve.
Preferably, in described flat bar sleeve, be provided with the passage that can be held push rod, spatula, be equipped with the window through with described passage in the front and back end of sleeve and top.
Preferably, be inserted with a push rod in described passage, be fixed with filter paper in the front end of push rod.
Preferably, the present invention adopts and once comes and goes self-locking mechanism.That is: first time releases push rod, and filter paper and the spatula below it are released in the lump, and hold sleeve and can gather Stomatocyte with filter paper, push back push rod, exert oneself a little, spatula is just caught on by the barb on plastic sleeve.Promote push rod forward later, can only filter paper be released, and the spatula below it is certainly locked in plastic sleeve and is not pushed out, thus facilitated machine or manual sampling of punching, realized the standardization sampled.
The present invention is relative to prior art, there is following beneficial effect: the present invention once comes and goes self-locking buccal cell collection and save set integrates buccal cell collection and hold function, simple to operation, sample is not easily contaminated, machine or manual punching sample all very convenient, thus easily realize the hands-free DNA of getting and directly increase, improve the efficiency of DNA Database, reduce the cost of DNA inspection.
Accompanying drawing explanation
Fig. 1 is the structural representation that the present invention once comes and goes self-locking buccal cell collection and save set.
Fig. 2 is sleeve, spatula, the push-rod assembly schematic perspective view that the present invention once comes and goes self-locking buccal cell collection and save set.
Detailed description of the invention
Below in conjunction with embodiment and accompanying drawing, the present invention is described in further detail, but working of an invention mode is not limited thereto.
As shown in Figure 1, 2, one once comes and goes self-locking buccal cell collection and save set, a flat bar plastic sleeve 1, the passage that can hold push rod 2 and spatula 3 is provided with in sleeve 1, the window through with described passage is equipped with in the front and back end of sleeve and top, be inserted with push rod 2 and spatula 3 in described passage, be fixed with filter paper 4 in the front end of push rod 2.First time promotes push rod 2 forward, and filter paper 4 and the spatula 3 below it are released in the lump, and hold sleeve 1 and can gather Stomatocyte with filter paper 4, push back push rod 2, exert oneself a little, spatula 3 is caught on by the barb (14) on plastic sleeve 1.Promote push rod 2 forward later, filter paper 4 can only be released, and the spatula 3 below it is certainly locked in plastic sleeve 1 and is not pushed out, thus facilitate machine or manual sampling of punching, realize the standardization of sampling, thus easily realize the hands-free DNA of getting and directly increase, improve the efficiency of DNA Database, reduce the cost of DNA inspection.
Above-described embodiment is only preferred embodiment of the present invention, is not used for limiting practical range of the present invention.Namely all equalizations done according to content of the present invention change and modify, all by the claims in the present invention scope required for protection is contained.
Claims (6)
1. one kind once comes and goes self-locking buccal cell collection and save set, it is characterized in that: comprise a flat bar plastic sleeve (1), the passage that one can be held push rod (2) and spatula (3) is provided with in sleeve, front end window A (11) of passage is released flexibly for push rod (2) and spatula (3), rear end window B (13) is in order to unlock, slide for push rod (2) assembling and push button (21) in top window C (12), push rod (2) and spatula (3) is inserted with in described passage, filter paper (4) is fixed with in the front end of push rod (2), push rod (2) below is spatula (3), spatula (3) is provided with a claw (31) and self-fastening button (32) away from filter paper end, sleeve bottom is provided with respective barbs (14).
2. once round self-locking buccal cell collection and save set according to claim 1, it is characterized in that: be provided with the passage that can be held push rod (2) and spatula (3) in described flat bar sleeve (1), be equipped with the window through with described passage in the front and back end of sleeve (1) and top.
3. once round self-locking buccal cell collection and save set according to claim 1, is characterized in that: be inserted with a push rod (2) and spatula (3) in described passage, be fixed with filter paper (4) in the front end of push rod.
4. according to claim 1ly once come and go self-locking buccal cell collection and save set, it is characterized in that: described filter paper (4) be harmless on human-body safety, do not affect the filter paper that DNA directly increases.
5. once round self-locking buccal cell collection and save set according to claim 1, it is characterized in that: when first time releases push rod (2), under the claw (31) of guide pillar (22) on spatula (3) is held below push rod, spatula (3) and filter paper (4) is driven to release from window A (11) in the lump.
6. once round self-locking buccal cell collection and save set according to claim 1, is characterized in that: after sampling, push back push rod (2), exert oneself a little, spatula (3) is locked in plastic sleeve (1) certainly, again promotes push rod (2) forward, just can only release filter paper (4).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201310427995.5A CN104434227B (en) | 2013-09-21 | 2013-09-21 | Once-reciprocating self-locking oral cell sampling and storing device |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN201310427995.5A CN104434227B (en) | 2013-09-21 | 2013-09-21 | Once-reciprocating self-locking oral cell sampling and storing device |
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CN104434227A true CN104434227A (en) | 2015-03-25 |
CN104434227B CN104434227B (en) | 2017-05-10 |
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CN201310427995.5A Active CN104434227B (en) | 2013-09-21 | 2013-09-21 | Once-reciprocating self-locking oral cell sampling and storing device |
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Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1379641A (en) * | 1999-10-18 | 2002-11-13 | 丹尼斯·马歇尔-弗雷泽 | Sample taking device |
US20030045814A1 (en) * | 2001-05-25 | 2003-03-06 | Sangha Jangbir S. | DNA collection device and storage method |
US8105549B2 (en) * | 2008-11-19 | 2012-01-31 | Sun Biomedical Laboratories, Inc | Sample collection device |
CN202446132U (en) * | 2012-01-20 | 2012-09-26 | 黄凤 | Cervical cell sampler |
US8323214B2 (en) * | 2010-10-27 | 2012-12-04 | Larry Hartselle | Oral testing devices and methods |
CN202776393U (en) * | 2012-09-04 | 2013-03-13 | 林士军 | Hand-held device for tongue depressor |
CN202982063U (en) * | 2009-03-18 | 2013-06-12 | 卡思特生物科学技术公司 | Saliva collection device |
CN203609454U (en) * | 2013-09-21 | 2014-05-28 | 邹建文 | One-time reciprocating type self-locking oral cavity cell acquisition and preservation device |
-
2013
- 2013-09-21 CN CN201310427995.5A patent/CN104434227B/en active Active
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1379641A (en) * | 1999-10-18 | 2002-11-13 | 丹尼斯·马歇尔-弗雷泽 | Sample taking device |
US20030045814A1 (en) * | 2001-05-25 | 2003-03-06 | Sangha Jangbir S. | DNA collection device and storage method |
US8105549B2 (en) * | 2008-11-19 | 2012-01-31 | Sun Biomedical Laboratories, Inc | Sample collection device |
CN202982063U (en) * | 2009-03-18 | 2013-06-12 | 卡思特生物科学技术公司 | Saliva collection device |
US8323214B2 (en) * | 2010-10-27 | 2012-12-04 | Larry Hartselle | Oral testing devices and methods |
CN202446132U (en) * | 2012-01-20 | 2012-09-26 | 黄凤 | Cervical cell sampler |
CN202776393U (en) * | 2012-09-04 | 2013-03-13 | 林士军 | Hand-held device for tongue depressor |
CN203609454U (en) * | 2013-09-21 | 2014-05-28 | 邹建文 | One-time reciprocating type self-locking oral cavity cell acquisition and preservation device |
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CN104434227B (en) | 2017-05-10 |
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