CN104434034B - Device is hindered in a kind of hand-held Near-infrared Brain hemotoncus inspection - Google Patents
Device is hindered in a kind of hand-held Near-infrared Brain hemotoncus inspection Download PDFInfo
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- CN104434034B CN104434034B CN201410717848.6A CN201410717848A CN104434034B CN 104434034 B CN104434034 B CN 104434034B CN 201410717848 A CN201410717848 A CN 201410717848A CN 104434034 B CN104434034 B CN 104434034B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
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Abstract
Device is hindered in a kind of hand-held Near-infrared Brain hemotoncus inspection, including the detector body containing light source probe and detector probe, also include a light shield that can be moved along detector body lower part slide-and-guide post, so that light shield covering light source probe and detector probe and head curved face contact formation darkroom during detection；Light source probe and detector probe used are spring probe mechanism in the present invention, include and possess independent elastic movement ability up and down in radome, mounting seat, spring and conical seat and fibre-optical probe, use, are suitable for head different curve shape；The present invention is also integrated with light source module, detector module and optical fiber/light source couples, the optical filtering of optical fiber/detector and coupled, and realizes the probe small cost convenient changing of consumptive material.
Description
Technical field
The invention belongs to Photobiology detection device, it is related to a kind of hand-held Near-infrared Brain hemotoncus inspection and hinders device.
Background technology
Fight scene, be inevitably present due to the mechanics such as exploding, falling and impacting in wartime, training, accident, disaster etc.
Factor, acts on human brain formation bleeding due to trauma, results in fatal intracranial hematoma.According to statistics, war dead in war
Scholar has nearly 50% to be because caused by head injuries.And usually, the craniocerebral injury caused by accident, traffic accident, disaster has turned into
Second is accounted for after tumour, cardiovascular and cerebrovascular diseases causes the cause of disease of death.
The treatment key of traumatic cerebral hemotoncus is promptly and accurately to detect, suits the medicine to the illness and dispose and sent after quick.Especially in wound
Afterwards l hours prime time section.However, due to lacking the objective reliable detection cephalophyma means that can be carried out at the scene, it is impossible to
Targetedly the cephalophyma wounded are given treatment to and after give, many wounded is lost optimal treatment opportunity.
At present, that cephalophyma accurately can be detected is computed tomography (CT), is referred to as diagnosing cranium
" goldstandard " of interior hemotoncus.However, CT equipment is expensive and is difficult to scene before institute, and it is small in rural area, community, remote districts
Medical institutions also do not popularize, using being above very limited；In addition, CT is not particularly suited for carrying out continuously wounded's cerebral hemorrhage situation
Detection.In addition, can not enter to the frequent of bleeding after the irremovable wounded, Delayed onset cerebral hemorrhage and cerebral operationses
Row detection.Accordingly, it would be desirable to a kind of Medical Instruments of portable, sustainable detection cephalophyma.
At present, the tissue such as skin, skull and its sensitiveness principle to intracranialing hemorrhage can be penetrated easily based near infrared light,
There is the portable brain hemotoncus detecting instrument using near infrared detection Technology design.
American documentation literature US8060189 discloses a kind of Near-infrared Brain hemotoncus detection system, its commercially produced product difference
For Inftrascanner1000/2000 type cephalophyma scanners.Wherein 1000 types are split-type design, by detector and PDA groups
Into both are coupled by bluetooth.2000 types are equipped for a new generation, are designed for integral type.Near-infrared is installed on the base of detector
Light source, near infrared detector and fibre-optical probe, but two fibre-optical probe is unable to self-movement, or fibre-optical probe is fixed on one
On the larger probe cover of volume, two probes are nonelastic, it is impossible to be adapted to the curved surface 3D shape of human body head, it is impossible to control measurement power
Degree, causes the increase of measurement error, the waste integrally abandoned in the presence of the probe cover high with cost during replacing, and carrying amount is limited；
Either 1000 types or 2000 types, are designed without reliable shading, it is impossible to which shielding influences huge extraneous ring on measurement result
Environmental light, causes the measurement error increase under outdoor or indoor strong ambient light.Current commercial Infrascanner
The major parameters of Model 1000 (come from FDA authentication documents) are：Fathom：3.5cm under epidermis；Minimum detectable range measures amount of bleeding
3.5ml；Detection sensitivity 88%, specificity 90.7%；Detection time 3min.
The content of the invention
To solve the above problems, it is an object of the invention to provide one kind can before institute and war scene without under the conditions of CT realize
To the handheld apparatus of the quick inspection of wounded's cephalophyma wound, it is characterized in portable, noninvasive, quick, it is accurate and do not need any examination
Agent.
The present invention uses following technical scheme：
Device, including the detector sheet containing light source probe and detector probe are hindered in a kind of hand-held Near-infrared Brain hemotoncus inspection
Body, in addition to a light shield, wherein, the detector body lower part sets slide-and-guide post, and light shield is by the soft material of dark shading
Material shaping, is the cover body to lower open mouth, is sleeved on detector sheet in vitro, light shield inside upper part is provided with and slide-and-guide post shapes
The sliding surface matched with size makes light shield realize relative motion with detector body to be socketed slide-and-guide post.
Apparatus described above, detector body exterior is for ease of the hollow housing of gripping, the cunning of lower housing section certain length
Action-oriented post outside dimensions is slightly less than housing epimere peripheral dimension, and distance is moved up to limit light shield；Housing lowermost end is provided with
Base, base dimensions move down size slightly larger than the peripheral dimension of slide-and-guide post with limit light shield；Base is equipped with downwards
The light source probe and detector probe of stretching.
In described device, when light shield moves up and down along along lead movable distance, the Design of length of light shield is：Make
It does not block light source probe and detector probe at the top of slide-and-guide post, while moving it to slide-and-guide post
Darkroom can be formed during bottom well beyond two probes, and with head curved face contact.
In described device, detector body interior is equipped with the i.e. left control of two pieces of parallel control boards perpendicular to base
Circuit board processed and right control board, the battery bin equipped with battery, battery the two poles of the earth are connected into control board；Light source probe and spy
Survey device probe distribution is connected with base and probe tip extends downwardly from base.
In described device, left control board, right control board, battery bin and light source probe and detector probe
Epimere be closed in the space that housing and base are surrounded, optimal distance between light source probe and the tip of detector probe two
For 3-5cm, battery, circuit board and probe epimere electrical connection.
In described device, the light source probe and detector probe are spring probe mechanism；The spring probe mechanism includes
There are radome, mounting seat, spring and conical seat and fibre-optical probe, wherein：
Radome is the cylindrical cavity with side open surface, and its upper end opens up the photoelectricity that through hole is used to draw installing in mounting seat
The power supply of element and control line, lower end set the bottom of evagination to be fixed with base, and radome bottom and base relative position are all provided with
There is opening；
Mounting seat is step-like hollow posts, is axially sleeved ikn in the cavity of radome and bottom passes through base, mounting seat is set
There is step convex tendon, its maximum outside diameter is equal with radome internal diameter, bottom minimum outer diameter is equal with the opening of base so that mounting seat
It can be fixedly mounted on base；
Mounting seat upper end is relative to be provided with two certain length elongated holes, and its step convex tendon top is provided with step, step and is arranged
Spring, the bottom of spring props up mounting seat design step convex tendon, and its drift is more than long hole length；
Conical seat is fixedly mounted on the bottom of mounting seat, and it has longitudinally mounted hole；
Fibre-optical probe is interspersed in fibre-optical probe mounting hole, installed in the bottom in mounting seat.
In described device, mounting seat is the step-like hollow posts of downward size reduction, is axially sleeved ikn the cavity of radome
Interior and bottom passes through the opening of base, and mounting seat design step convex tendon, its maximum outside diameter is equal with radome internal diameter, and bottom is minimum
External diameter is equal with the opening of base, and mounting seat is fixedly mounted on base；
In upper end, be provided with two longitudinal directions has the elongated hole of certain length to mounting seat relatively, and its step convex tendon top is provided with step,
Sheathed spring on step, the bottom of spring props up mounting seat design step convex tendon, and its drift is higher than the bottom of elongated hole；Screen
The relevant position for covering cover is also provided with screw, and spring bottom props up the step convex tendon of mounting seat, temporarily will during installation with instrument or hand
The elongated hole of spring top compression to mounting seat is following topmost, and can reserve the space of screw screw-in, and length can be stretched into length
Hole 2-4mm screw is from radome screw screws in mounting seat elongated hole, and the height design of radome screw just screws in screw
Afterwards positioned at elongated hole the top of mounting seat, pressuring spring is made spring have at the top of certain pre- elasticity, mounting seat with shielding by screw
There is a displacement to realize that mounting seat moves upward and downward elastically certain distance between the top for covering cover.
In described device, LD light source modules are from top to bottom equiped with the mounting seat for installing light source probe and collimation is saturating
The distance of mirror, collimation lens and LD light source modules lower end is 1-4mm；Or, in the mounting seat for installing detector probe by
Accurate photodiode and optical filter are equipped with, the upper end of fibre-optical probe is close to install with optical filter.
In described device, longitudinal hole is fibre-optical probe mounting hole inside the conical seat, is set in its cylinder partial bottom
Steel ball, spring and jackscrew are installed from the inside to the outside respectively in two laterally inwardly tapered centre bores, centre bore；
The fibre-optical probe is constituted and is integral by fibre-optical probe seat, optical fiber protective tube and optical fiber, and optical fiber is arranged in optical fiber
In protection pipe, optical fiber front end is hemisphere face and slightly forward extends out optical fiber protective tube, and fiber termination box optical fiber protective tube is fixed on fiber bench
It is interior.
In described device, the housing top sets display module, and battery cabin cap, power switch and function button are fixed on
Housing side is suitable to the position of operation or viewing；
Left control board, right control board, display module, power switch, function button, LD light in detector body
The parts such as source module, accurate photodiode, battery are electrically connected to form circuit control system, wherein right control board realizes system
The major control function of system, including the state of power switch, function button is detected, to LD light source modules, display module
Etc. being controlled；Left control board mainly realizes power supply and to accurate photodiode measurement data acquisition, left control circuit
The DC/DC chips of plate are connected with battery, and signal amplification circuit is connected with accurate photodiode, and accurate photodiode is faint
The amplification of current signal is simultaneously converted into voltage signal；AD sampling A/D chips are connected with signal amplification circuit, by amplifying circuit
Analog signal is converted to data signal, and sends a signal to right control board.
Designed more than, the present invention realizes near infrared light detection cephalophyma with relatively easy reliable structure and design
The function of the wounded；It is mainly characterized in that：
1. integrated form fibre-optical probe, following functions can be realized simultaneously：
● light source probe and the motion of detector probe standalone elastic, it is suitable for head different curve shape；
● the structure that design can be electromagnetically shielded to internal circuit realiration, detector is avoided by external interference.
● light source module, detector module and optical fiber/light source couples, the optical filtering of optical fiber/detector are integrated with coupling.
● realize the probe small cost convenient changing of consumptive material.
2. devise the light shield that can slide up and down
Up, testing staff can accurately judge the fibre-optical probe feelings of the contact with wounded's scalp to light shield when detecting the wounded
Condition, after confirming that fibre-optical probe is contacted with wounded's scalp, promotes light shield, light shield is formed secretly with wounded head curved surface still further below
Room, blocks extraneous light entrance, prevents the ambient interferometries such as outdoor or indoor strong light.
Brief description of the drawings
Figure 1A is that Near-infrared Brain hemotoncus detector of the present invention is constituted and schematic appearance.
Figure 1B moves schematic diagram in the direction of the arrow for light shield in Near-infrared Brain hemotoncus detector.
Fig. 1 C are shading cover structure composition schematic diagram
Fig. 2A and Fig. 2 B constitute schematic diagram for the outside of detector body 1.
Fig. 3 A and Fig. 3 B are the Inner Constitution schematic diagram of detector body 1.
Fig. 3 C are the base of detector body 1 and probe positions and connection figure.
Fig. 4 A are the structure chart of elastic probe mechanism in the present invention.
Fig. 4 B remove structural representation after radome and spring for spring probe mechanism and (further illustrate spring probe mechanism
The schematic diagram of structure).
Fig. 4 C are spring probe schematic diagram of mechanism movement.
Fig. 5 A are the schematic diagram of replaceable fibre-optical probe structure in the present invention.
Fig. 5 B are taper mounting seat structural representation.
Fig. 5 C coordinate mounting structure figure for fibre-optical probe in the present invention and taper mounting seat.
Fig. 5 D are fibre-optical probe structure chart in the present invention.
The photoelectric cell of Fig. 6 A display light sources probe.
Fig. 6 B show the photoelectric cell of detector probe.
Fig. 7 is the circuit controling drawing of Near-infrared Brain hemotoncus detector of the present invention.
Fig. 8 is Near-infrared Brain hemotoncus detector measurement procedure figure of the present invention.
Fig. 9 A are the graph of a relation of light source luminous power and time in generally detection.
The graph of a relation of light source luminous power and time during Fig. 9 B detect for the present invention.
No. 1 wounded brain CT photo (left temporal lobe intradural hematoma) that Figure 10 A detect for the present invention.
No. 8 wounded brain CT photos (right parietal lobe hemotoncus) that Figure 10 B detect for the present invention.
Embodiment
The inspection of near-infrared hand-held cephalophyma hinder instrument be mainly used in before institute, war scene etc. without being used in the case of CT, can early stage it is fast
In speed detection traumatic cerebral hemotoncus, including frontal lobe, temporal lobe, top and occipital lobe cranium brain position dura mater, Subdural space, arachnoid and brain skin
Matter hemotoncus, makes the cephalophyma wounded timely be given treatment to.
Its technical principle：Wavelength 600-900nm near infrared light has good penetrability to skin, skull, based on encephalic
Hemotoncus and non-Hemorrhagic location are to near-infrared absorption difference of coefficients (generally up to more than 10 times), by comparing the symmetrical portion of wounded's brain
Position judges intracranial hematoma risk to the absorption characteristic of near infrared light.
Wherein, Δ OD is both sides poor optical density, INFor normal side optical density, IHFor hemotoncus sidelight density.
The present invention utilizes the new near-infrared hand-held cephalophyma inspection of the principle design to hinder instrument.Provide below in conjunction with the accompanying drawings
Embodiment illustrates specific composition, operation principle and the detection process of the present invention.
Figure 1A and Figure 1B show Near-infrared Brain hemotoncus detector pie graph of the present invention, and it includes detector body 1 and screening
Light shield 2 (see Figure 1B) two parts, wherein, the outward appearance of detector body 1 sets for ease of the ergonomic designs of gripping in its lower end
Have for one section of smaller slide-and-guide post 14 of the descending Outside Dimensions of light shield 2 (with reference to shown in Fig. 2A)；Light shield 2 is by dark shading
Soft material such as silica gel, rubber or the shaping of other similar materials, it is sleeved on outside the lower slide lead 14 of detector body 1,
The inside upper part of light shield 2 is provided with the sliding pair matched with the shape of slide-and-guide post 14 and size, as shown in Figure 1 C, for example, hiding
The inner side of light shield 2 is designed with the slide unit 21 being engaged with the form factor of slide-and-guide post 14, the slide unit 21 by nylon or
The small polymer material molding of other frictional resistance, surface is smooth, and one end can be embedded in the groove that the soft cover body 22 of light shield 2 is designed
In, the other end is fastened in the outer rim of slide-and-guide post 14, is contacted when sliding with slide-and-guide post 14 and is easy to relative motion, makes shading
Cover 2 can move a distance along the slide-and-guide post 14 of detector body 1；When light shield 2 is moved down into the bottom of detector body 1
During 15 (shown in Fig. 2A) place of seat, with reference to shown in Figure 1B, because the design of the outer of base 15 protrudes from slide-and-guide post 14, shading is blocked
Cover 2 can not be moved still further below, form certain displacement：(the detector body when moving to the top of distance on light shield 2
1 epimere size stops that light shield 2 continues to move up slightly larger than the Outside Dimensions of slide-and-guide post 14), make to expose before detector body 1
The probe 18,19 (with reference to shown in Fig. 2A) at end, the person of being convenient for measuring judges whether contacted with the scalp of the wounded in measurement；Work as shading
Cover 2 is when being displaced downwardly to the bottom of distance (design of the outer of base 15 protrudes from slide-and-guide post 14, block light shield 2 can not again to
Lower movement), the design of its displacement makes the lower edge of soft cover body 22 of light shield 2 exceed probe 18,19, in order in probe and head
While portion's curved face contact, light shield 2 is collectively forming local darkroom with head, can stop that extraneous light enters probe, reduces outer
Influence of boundary's light to detection.
Fig. 2A and Fig. 2 B show the outside composition of detector body 1.It includes one by high polymer material (such as ABS, PVC
Deng) material injection forms, shape is easy to the hollow housing 12 that grips, housing top fixes display module 11, battery cabin cap 13,
The funtion part such as power switch 16 and function button 17 by buckle and be threadedly secured in housing side be suitable to operation or viewing
The slide-and-guide post 14 that peripheral dimension is slightly less than housing 12 is extended in position, the bottom of housing 12, and the lowermost end of housing 12 is provided with bottom
Seat 15, the outside dimensions of base 15 is slightly larger than the peripheral dimension of slide-and-guide post 14, and base 15 is equipped with the light source extended downwardly from and visited
First 18 and detector probe 19.
Fig. 3 A and Fig. 3 B show the Inner Constitution of detector body 1, including pass through grafting and be threadedly coupled and base
15 fastenings and vertically two pieces of parallel control boards with base, i.e., left control board 31 and right control board 32 are left
The side of control board 31 and the parallel edges of right control board 32 is vertical to set battery bin 33, wherein installing 2AA batteries, by
Located at the fetching battery of battery cabin cap 13 of outside correspondence position, battery the two poles of the earth are connected into circuit board, and all circuit systems pass through mark
Quasi- connection-peg, which is powered, to be connected, and being powered by 2AA batteries, (battery is powered to be formed surely by the power management chip in control board
Fixed ± 12V ,+5V ,+3V are powered to modules respectively).Light source probe 18 and the distributing installation of detector probe 19 are on a left side
It is connected in the middle of control board 31 and right control board 32 and with base 15, with reference to Fig. 3 C, light source probe 18, detector probe
19 have threaded mounting hole, are fixed and are fixedly connected with base 15 by screw, probe tip (referring to Fig. 3 C) extends downwardly from base 15,
And optimal distance is 3-5cm between 19 liang of tips of light source probe 18 and detector probe.During assembling, left control board 31, the right side
The epimere of control board 32, battery bin 33 and light source probe 18 and detector probe 19 is closed in housing 12 and bottom
In the space that seat 15 is surrounded, electrically connected between battery, circuit board and probe, be thusly-formed detector body 1.
In the present invention, light source probe 18 and the optimal design of detector probe 19 are into spring probe mechanism.
Fig. 4 A, 4B, 4C illustrate the composition of the spring probe mechanism by taking light source probe 18 as an example.Light source probe 18 includes screen
Cover 181, mounting seat 182, spring 183 and conical seat 184 and fibre-optical probe 185 are covered, wherein, radome 181 is that band side is opened wide
The cylindrical cavity (referring to Fig. 3 C and Fig. 4 A) in face, being made up of metal materials such as aluminium, copper, steel (can be to internal circuit realiration electromagnetic screen
Cover, detector is avoided by external interference), its upper end, which opens up through hole, is used to draw the photoelectric cell of installing in mounting seat 182
Power supply and control line, lower end set the bottom of evagination to be fixed with base 15, and the bottom of radome 181 and the relative position of base 15 have
Opening.Mounting seat 182 is the step-like hollow posts of downward size reduction, is axially sleeved ikn in the cavity of radome 181 and bottom
Through the opening of base 15, the design step convex tendon of mounting seat 182, its maximum outside diameter is equal with the internal diameter of radome 181, and bottom is minimum
External diameter is equal with the opening of base 15, and matching design is that mounting seat 182 provides motion guide, such energy of mounting seat 182 at two
Enough it is fixedly mounted on base 15.In upper end, be provided with two longitudinal directions has the elongated hole 1821 of certain length to mounting seat 182 relatively, its
Rank convex tendon top is provided with sheathed spring 183 on step, step, and the bottom of spring 183 props up the design step convex tendon of mounting seat 182,
Its drift is higher than the bottom of elongated hole 1821.The relevant position of radome 181 is also provided with screw 190, first will during installation
Spring 183 is compressed to below the height of elongated hole 1821 of mounting seat 182, can be penetrated two elongated holes 1821 using length and be stretched into wherein 2-
4mm screw is screwed in the upper end elongated hole 1821 of mounting seat 182 from the screw 190 of radome 181, because the bottom of spring 183 is propped up
Mounting seat 182 designs step convex tendon, and upper end screw pressuring spring 183 makes spring 183 have certain pre- elasticity, mounting seat 182
Having a distance to turn between top and the top of radome 181, " mounting seat 182 can be achieved flexibly in displacement d " (Fig. 4 C)
Move up and down a certain distance.In addition, the screw that the 2-4mm of two elongated holes 1821 can be stretched into using length can be while prevent mounting seat
182 with the rotary motion of radome 181, the rotary motion may cause the inner lead of mounting seat 182 damage (referring to Fig. 6 A,
For being from top to bottom equiped with LD light source modules 186 and collimation lens 188 inside the mounting seat of light source device probe 18；For detection
Accurate photodiode 191 and optical filter 192 are from top to bottom equipped with the mounting seat of device probe 19, referring to Fig. 6 B).
Equally, detector probe 19 possesses independent elastic movement ability up and down by same mode.
Continuing with shown in Fig. 5 A, Fig. 5 B, Fig. 5 C and Fig. 5 D, it is shown that replaceable fibre-optical probe structure of the invention：Taper
Seat 184 is arranged on by way of being bonded or being threadedly coupled in the bottom of mounting seat 182, and Fig. 5 B show that the inside of conical seat 184 is vertical
To provided with through hole, as the fibre-optical probe mounting hole 1845 of fibre-optical probe 185, installation direction is (Fig. 5 C display peaces from bottom to top
Dress process).Conical seat 184 is provided with two horizontal elongated holes in cylinder partial bottom, and the endoporus of elongated hole is the centre bore being inwardly tapered
1841, steel ball 1843,1,842 3 parts of spring 1844 and jackscrew are installed from the inside to the outside respectively, due to centre bore 1841 in hole
Minimum-value aperture design is less than the diameter of steel ball 1843, and with steel ball 1843 after the pretension of jackscrew 1842, elasticity is prominent in centre bore 1841
Go out, fibre-optical probe 185 is interspersed in 1845 in fibre-optical probe mounting hole.The present invention realizes optical fiber by changing fibre-optical probe structure
The replacing of probe consumptive material.When fibre-optical probe 185 is inserted, the groove of its upper design can with can be with conical seat 184 centre bore
The steel ball 1843 that elasticity is prominent into mounting hole 1845 in 1841 coordinates, and the position of fibre-optical probe 185 is fixed on conical seat 184
It is interior, it will not drop out, change convenient, while light conduction function can be completed.After detection finishes a wounded, can conveniently with hand to
Lower force drawn optical fiber probe 185, the fibre-optical probe 185 more renewed.
Continuing with shown in Fig. 5 D, fibre-optical probe 185 is made up of three parts, fibre-optical probe seat 1851 and optical fiber protective tube
1852 and optical fiber 1853 be bonded or one-shot forming, integrally can be changed as consumptive material；Optical fiber protective tube 1852 is metal or other materials
Material is made, and optical fiber 1853 can be effectively protected, and prevents light from directly being propagated between being popped one's head in two, causes measurement to be lost
Lose；It is uncomfortable when being contacted with reducing with head part's skin that optical fiber 1853 is designed as hemisphere face with human body contact portion's (lowermost end)
Sense.The performance simple in construction of fibre-optical probe 185 of the design is reliable, and manufacturing cost and technology difficulty are very low, it is ensured that it turns into
Droppable low value consumptive material.
Light source probe 18 of the present invention, detector probe 19 can be using identical fibre-optical probes as shown in Figure 5 D
185, such light source probe 18 and detector probe 19 can facilitate the replacing fibre-optical probe 185 of no differentiation.
In the present invention, Fig. 6 A show the optical element of light source probe 18.The light source module 186 installed in mounting seat 182
For LD light source modules (inside includes LD lasers, module mounting seat and control circuit), LD light source modules can be screwed in by screw thread
In mounting seat 182 (referring to Fig. 5 A and Fig. 5 B), collimation lens 188 is screwed in mounting seat 182 from below also by screw thread, itself and light
The distance of the lower end of source module 186 is 1-4mm.The near infrared light for the 808nm that LD light source modules 186 are sent passes through collimation lens 188
After be coupled to the upper surface of fibre-optical probe 185, (such as Fig. 6 A directions of arrow) is exported by the optical fiber 1853 in fibre-optical probe, light source is realized
The function of light path.
Fig. 6 B show the optical element of detector probe 19.In mounting seat 182, accurate photodiode is arranged at top
191 (carrying primary operational amplification circuit), installation optical filter 192 immediately below it, upper end and the optical filter 192 of fibre-optical probe 185
It is close to install to ensure the coupling efficiency of light.The light (such as Fig. 6 B directions of arrow) of return is scattered from brain tissue by fibre-optical probe
Optical fiber 1853 in 185 is imported, and filters out wherein most non-808nm infrared lights to reduce ambient by optical filter 192
Interference, be coupled into accurate photodiode 191, realize detection light path function.It is (detailed below by circuit control system
State) optical signal that gathers accurate photodiode 191 is converted to electric signal and drawn by lead from the upper end through hole of radome 181
Go out to display module 11.
The circuit control system of the present invention is shown in Fig. 7, including left control board 31, right control board 32, display module
11st, the part such as power switch 16, function button 17, LD light source modules 186, accurate photodiode 191, battery, each part connects
Relation is connect as shown in fig. 7, the direction of arrow is that data or signal are flowed in figure.Right control board 32 realizes the major control of system
Function, including the state of power switch 16, function button 17 is detected, LD light source modules 186, display module 11 etc. are entered
Row control；Left control board 31 mainly realizes power supply and to the accurate measurement data acquisition of photodiode 191.
Wherein：Left control board 31 is mainly made up of known DC/DC chips, signal amplification circuit, AD sampling A/D chips.
DC/DC chips are connected with battery, by 2 section No. 5 dry cells 2-3V voltage conversions for the stabilization needed for circuit system 3.3V,
5V, ± 12V voltages, to system power supply, all circuit system elements are powered by standard connection-peg and connected.Signal amplification circuit
It is connected with accurate photodiode 191, the main amplification for realizing the accurate low current signal of photodiode 191 is converted
For voltage signal；AD sampling A/D chips are connected with signal amplification circuit, and the analog signal of amplifying circuit is converted into data signal, and
Send a signal to right control board 32.
Here, signal amplification circuit generally will be comprising more than two-stage.Under a kind of implementation, two-stage amplifying circuit is designed,
The low current signal of accurate photodiode 191 is transformed to mV magnitude voltage signals, second level amplification electricity by primary amplifying circuit
The signal is further amplified again on road.Because the measurement signal of accurate photodiode 191 is by skull thickness, hair density degree
Deng influence so that measurement signal individual difference is huge, to meet dynamic measurement request, design second level amplifying circuit, which can be realized, to be put
The dynamic adjustment of large gain (specific method of adjustment is detailed below).Under another implementation, the third level can also be designed and put
Big circuit, it is therefore intended that the filtering of signal can be realized on this grade of amplifying circuit.Primary amplifying circuit typically from specifically designed for
The amplifying circuit chip of photodiode signal processing, such as OPA128, second, third grade of amplifying circuit can select general put
Big device is realized.
It should be noted that sample frequency (being usually not less than 1MHz), minimum 10 of measurement accuracy, one on AD sampling A/D chips are chosen
AD7960 can be chosen by planting implementation.
Right control board 32 is mainly made up of SCM system, and a kind of implementation can use 51 series monolithics, such as
C8051F330, its rich interface has UART serial ports to facilitate and is connected with display module 11, has SPI serial ports to facilitate and left control
Circuit board 31 AD sampling A/D chips connection, digital I/O mouthfuls respectively with power switch 16, function button 17 and LD light source modules 186
Connection, can be achieved the detection and the control of LD light source modules of power switch and function button.
It is mounted with single-chip microcomputer：1) photo densitometry algorithm known to, the algorithm is according to the sensitive of photodiode 191
Degree, the digital-to-analogue corresponding relation of circuit multiplication factor, AD sampling determine the luminous power that measures, then the luminous power is taken be with 10
The logarithm at bottom obtains optical density；
2) default test point sequential programme, this is sequentially preset as left frontal lobe LF/ right frontal lobes RF, LT left temporal lobe/right temporal lobe
RT, left parietal lobe LP/ right parietal lobe RP, left occipital lobe LO/ right occipital lobes RO order, the number of times of pressing of function button 17 correspond to measurement point
Order realizes the optical density under point-to-point measurement each position；
3) switching programme of LD light source modules 186, LD light source modules are modulated to the pulse that width is 10ms, and the pulse spacing is about
167ms, then open light source during sampling, and other time light source is closed.
4) the multiplication factor adjustment programme of the power output of LD light sources and circuit：Light source power may be configured as 2 power shelves,
The different luminous power of correspondence, for example, can be set the light source peak power output that power shelves 1,2 correspond to 100%, 20% respectively.Measurement
The multiplication factor of circuit can be realized by using the amplifier amplifier of adjustable multiplication factor, generally by the adjustment of multiplication factor
Be arranged on the afterbody amplifier of amplifying circuit, using 3 gears, the multiplication factor of afterbody may be configured as 1,10,
100.Luminous power has 9 to combine with multiplication factor, and this 9 combinations of programme-control detect measurement point one by one in a fixed order,
Obtain data.The data finally chosen are the data in the 10%-70% of detection circuit measuring scope.
Accurate photodiode 191：Dark current small (being less than 30pA under normal circumstances) should be chosen and measurement frequency band is wider
The chip of (band is wider than 1KHz), chip 800nm or so near infrared region measurement sensitivity in 0.5A/W, a kind of implementation
The optical S2386 in the shore river in Jiangsu Province which flows into the Huangpu River of Shanghai may be selected.
LD light source modules 186：The LD modules of strobe pulse modulation, the modulating frequency of LD light sources should be (different more than 10KHz
In existing continuous light-brain hemotoncus detection device, existing equipment frequency is close to 100Hz), the present invention is made using pulse modulated LD
For light source, the LD light source controls mode (controlling pulse type switch by single-chip microcomputer) and accurate photodiode data for coordinating optimization are adopted
Sample, can be achieved the measurement under low light source mean power, and its advantage is needed for measurement is made under ensureing same measurement sensitivity
Luminous power is minimum, so as to greatly reduce the risk of measurement.LD light source modules 186 contain driving LD constant-current source circuit,
And can realize by adjusting resistance or voltage to control Output optical power.LD constant-current source circuits can be taken under a kind of implementation
Chip TCA62723 is realized.
Display module 11：Mainly realize the functions such as the prompting of measurement position in measurement process, the display of measurement result.One
Plant under implementation, display module can take LED screen, be characterized in low in energy consumption；Under another implementation, display module
Charactron can be taken, intuitive display is characterized in, realizes simply；Under another implementation, display module can take dot matrix
Lcd screen, is characterized in that display content is enriched.
Each part assembling of the design by more than obtains Near-infrared Brain hemotoncus detector of the present invention.
Detected that idiographic flow is referring to Fig. 8 using the Near-infrared Brain hemotoncus detector.Process includes：
(1) personnel are detected to be checked with sitting posture or prone position, head dirt should be cleared up before detection；
(2) detector is opened by power switch 16；
(3) fibre-optical probe 185 of assembling light source probe 18 and detector probe 19；
(4) push test position hair aside with hand, expose scalp, fibre-optical probe 185 is touched into scalp (light source probe 18 and spy
Device probe 19 is surveyed to be located in the middle of test position), probe orientation is tested skull face normal direction；
(5) press down on detector housing, so that it may which the elasticity of compression is popped one's head in, by flexible stroke (in relaxing of spring state)
It is pressed into total travel (to spring-compressed state)；Total travel refers to spring-compressed distance, the displacement for being Fig. 4.
(6) push light shield 2 to cover probe completely, stop interference of the extraneous light to measurement；
(7) press function button 17 to measure, show measurement position OD value OD (generally to display module 11
Time of measuring is 10s), the measurement of this test position is finished；
(8) light shield 2 is pushed up, the step of repeating (4)-(7) is detected to next measurement position；
(9) after 8 measurement points are measured, program automatic start is calculated, and measurement result is shown after the completion of test.
Here：In step (7), for each measurement point, instrument will obtain the measurement point as the light obtained by LD light sources irradiate
Density value OD, if the sensitivity of photoelectric diode is S (unit is A/W), if the gain of primary amplifying circuit is O1(unit is V/
A), the 2nd, 3rd level overall gain is O2, amplifying circuit output signal voltage Va, then
V0=ODSO1·O2
Optimization one：To improve measurement data anti-interference, each measurement point to be carried out that measurement is repeated several times to eliminate list
The error of secondary measurement；Simultaneously to eliminate influence of the bias light to measurement, light source do not opened and entered respectively with the signal after opening
Row measurement.If duplicate measurements number of times is n, light source does not open lower OD value average out to ODc, the optical density that light source is measured after opening
Average value is ODo, then have：
The OD value OD of final current measurement point is the poor OD after light source unlatching with OD average before unlatchingo-ODc,
So as to effectively eliminate the interference of bias light.
Optimization two：To realize the target that light source power is greatly reduced on the premise of measurement sensitivity is not influenceed, it is necessary to right
LD light source control modes are optimized.Its major measure be only allow sampling during open at light source, other time light source
In closed mode, (by programme-control, from pulse modulated light source, the switch of the type light source is defeated by single-chip microcomputer numeral
Go out the level of pin to control, opened and closed so as to convenient control light source).With each measurement point 10s time of measuring (this
It is the common time of measuring of each measurement point of the quasi-instrument) exemplified by, illustrate the advantage for optimizing LD light source control modes.It is common to do
Method is (to be pressed to the point measurement from function button to terminate, 10s) during current measurement point is measured, and LD light sources are in all the time
Opening, then luminous power and the relation of time are shown in Fig. 9 A.The present invention sets the AD sampling times as 10ms, each every kind of light of measurement point
It is 10 that power, which combines down duplicate measurements number of times with multiplication factor, then luminous power and the relation of time are shown in Fig. 9 B after optimizing, it is seen then that this
Invention LD modulation of source is the pulse that width is 10ms, pulse spacing about 167ms.Compare the radiated light energy of LD light sources (by scheming
Middle TG-AUC, which is calculated, to be obtained), under measuring method before optimization, the radiated light energy of single measurement point is 0.175J (figures
9A), and after optimizing, the radiated light energy of single measurement point is 0.0105J (Fig. 9 B).Radiated light energy greatly declines after optimization
(for 6% before optimization), effectively reduces the power consumption of instrument, while improving the security of measurement laser.
Optimization three：To make measuring instrument adapt to huge individual difference, the output work of LD light sources should be dynamically adjusted in measurement
The multiplication factor of rate and circuit.Under a kind of implementation, light source power can be set to 2 grades (Output optical power be respectively 30mW with
5mW), the overall gain of amplifying circuit is set to 3 grades (respectively ) (light source work(
The adjustment of rate by adjusting light source power supply electric current, light source is powered by constant-current source, can adjust the supply current of constant-current source
Adjust light source output power), then it can be measured in each measurement point according to the combination of different luminous power and gain amplifier,
Final optical power value chooses signal amplitude (initial data of optical density computing) numerical value placed in the middle, so as to be prevented effectively from signal
Situation too small or beyond measurement range.Such as circuit measuring scope is 0-5V, then measurement data generally chooses 0.1V-4.5V's
Data.
Here, detection ordering in step (8):A kind of order is testing staff according to the left temporo of left frontal lobe LF/ right frontal lobes RF, LT
Leaf/right temporal lobe RT, left parietal lobe LP/ right parietal lobe RP, left occipital lobe LO/ right occipital lobes RO order is detected (in detector single-chip microcomputer
In preset measuring sequence, every bit presses a function button 17), note detection when symmetrical position difference must not be big
In 3cm.After this 8 measurement points are measured, measurement result is shown on display module.
Another order is to coordinate function button 17 to realize the selection of measurement position sequencing：Long-press function button 17
The order of current measurement position can be changed, if thinking first to measure right temporal lobe, then can 3 long-press function buttons, first skip left frontal lobe,
The measurement of right frontal lobe, left temporal lobe.After required measurement point is measured according to the selecting sequence of user, detector display is surveyed
Measure result.Such implementation advantage is that providing facility to user (for example checks certain determination position, then need not
8 measurement points are carried out to be detected one by one) so that measuring sequence is not only in accordance with the progress being previously set.
Here, in step (9), after 8 measurement points are measured, single-chip microcomputer starts to calculate measurement result.If left side
Volume, temporo, top, the optical density of pillow are designated as OD respectivelyLF、ODLT、ODLP、ODLO, right side volume, temporo, top, the optical density of pillow are designated as respectively
ODRF、ODRT、ODRP、ODRO, then volume, temporo, top, the poor optical density of 4 groups of antimeres of pillow are respectively：
ΔODF=ODLF-ODRF
ΔODT=ODLT-ODRT
ΔODP=ODLP-ODRP
ΔODO=ODLO-ODRO
As long as volume, temporo, top, the poor optical density of pillow have absolute value to be more than 0.3, then judge there is cephalophyma, poor optical density
Be canonical on right side, to be negative then in left side.If volume, temporo, top, the absolute value of the poor optical density of pillow are more than 0.2 and are less than or equal to
0.3, then suspect the excessive risk that there is cephalophyma, poor optical density is that canonical is suspected on right side, is then suspected in left side to be negative.If volume,
Temporo, top, the absolute value of the poor optical density of pillow are respectively less than and are equal to 0.2, then judge no cephalophyma.For example, if optical density difference
According to for (frontal lobe F) -0.12, (temporal lobe T) is 0.37, and (top P) is -0.25, and (occipital lobe O) is 0.06, then is determined as right side temporal lobe
There is hemotoncus, left side top suspects the risk for having hemotoncus, and frontal lobe is with occipital lobe without hemotoncus.
Detection example (clinical test)：
Clinical examination has been carried out (with Nao Ke hospitals of affiliated hospital of People's Armed Police's logistics institute, the Temple of Heaven using instrument model machine of the present invention
Hospital cooperates), interim result shows, the detection specificity of model machine and sensitivity meet design requirement, 9 all wounded
Test result is consistent with CT scan result, and Figure 10 A left figures are that the CT figures on No. 1 wounded head, right figure are apparatus of the present invention detection figure,
Equally, Figure 10 B left figures are the CT pictures on No. 8 wounded heads, and right figure is that apparatus of the present invention detect figure, 9 wounded of all detections
Testing result is shown in Table 1.Confirm the validity of near-infrared hand-held cephalophyma detector application.
The clinical test results of table 1 (3 9 wounded of male 6 female of age 19-85 Sui)
| Sequence number | CT testing results | Present apparatus testing result |
| 1 | Left temporo intradural hematoma, about 30ml | Left temporal lobe hematoma, frontal lobe is normal |
| 2 | Right parietal lobe intradural hematoma, 5ml | Right parietal lobe hemotoncus, temporal lobe is normal |
| 3 | Contre coup injury, left top, temporal lobe hematoma 50ml | Left top, temporal lobe hematoma, frontal lobe are normal |
| 4 | Contre coup injury, left temporal lobe hematoma 10ml | Left temporal lobe hematoma, frontal lobe, top are normal |
| 5 | Right frontal lobe subdural hematoma about 40ml | Right frontal lobe hemotoncus, top, temporal lobe are normal |
| 6 | Left temporal lobe subdural hematoma 30ml | Left temporal lobe hematoma, frontal lobe, top are normal |
| 7 | Left pillow, top intradural hematoma 10ml | Left occipital lobe, left parietal lobe hemotoncus volume, temporal lobe are normal |
| 8 | Right parietal lobe subdural hematoma 20ml | Right parietal lobe hemotoncus frontal lobe is normal |
| 9 | Left frontal lobe contre coup injury hemotoncus 5ml | Left frontal lobe hemotoncus, top, temporal lobe are normal |
By taking No. 1 wounded as an example, its each location detection data such as table 2：
The detection data of 2 No. 1 wounded of table
| Frontal lobe F | Temporal lobe T | Top P | Occipital lobe O | |
| Left side measured value ODL | 4.11 | 3.25 | 3.12 | 3.65 |
| Right side measured value ODR | 3.99 | 3.67 | 3.25 | 3.76 |
| Poor optical density Δ OD | 0.12 | 0.42 | 0.13 | 0.11 |
From the measurement data of table 2, frontal lobe, temporal lobe, top and the occipital lobe that have detected No. 1 wounded respectively with this detector are left
Right symmetric part totally 8 data, wherein, the poor optical density of frontal lobe, top and occipital lobe is respectively less than 0.3, can determine that No. 1 wounded's volume
Leaf, top and occipital lobe are without hemotoncus.The measurement result of its temporal lobe shows that it is 0.42 that left and right poor optical density, which is more than, more than decision content
0.3, thus, it is believed that No. 1 wounded's temporal lobe part has cephalophyma, and because left side measured value is smaller, therefore, instrument judges 1
There is cephalophyma in the left temporal lobe of number wounded.The Cranial Computed Tomography scanning result of No. 1 wounded with reference to shown in Figure 10 A, CT scan result is also sentenced
There is cephalophyma in the left temporal lobe of fixed No. 1 wounded, both testing results are consistent.The Cranial Computed Tomography for No. 8 wounded that Figure 10 B are shown is swept
Result is retouched also to coincide with this detector testing result.
Feature of the present invention：
1. integrated form fibre-optical probe, following functions can be realized simultaneously：
● light source probe 18 and the motion of the respective standalone elastic of detector probe 19, it is suitable for head different curve shape.
United States Patent (USP) US8060189 Figure 15 B show that it realizes the mode of fibre-optical probe elasticity, light source probe and detector
Probe (label 1428) respectively on connect spring (bias elements1560), installed in hard planar delta part (platform
1510) on, however, this implementation there are problems that, two probe is arranged on a hard planar delta part,
And this rigid planar part (label 1510) is limited by three guide pillars (label 1505), its planar delta part 1510 and probe
1428 can only move up and down simultaneously, and although this design method makes probe possess elasticity, but exist it is following can not overcome lack
Point：
(1) between light source probe and detector probe can not self-movement, two probe motions be it is identical, i.e.,
The athletic meeting of one probe influences the motion that another is popped one's head in, and so causes it complex-curved incompatible with human body head, leads
Cause probe can not well be attached with the curved surface of human body head, have impact on the degree of accuracy of measurement.
(2) this design probe and light source or detector direct-coupling, cause the non-exchange of consumptive material of popping one's head in.
(3) complicated, volume is big, have compressed the layout of other necessary parts.
Therefore, although United States Patent (USP) US8060189 refer to elastic problem in the claims, and claim to scheme A side
Formula solves probe elastic problem, due to three above it is apparent the problem of, in practice and be not implemented.Its disclosed product
The scheme that B is schemed in patent is actually employed in the type cephalophyma scanning ceremony of 1000 types/2000, i.e. do not set using spring probe
Meter, realizes probe (Figure 16 E) as the replaceability of consumptive material.
However, Figure 16 E design but bring problem：United States Patent (USP) US8060189 also indicates that probe is flexible
Importance, one is that can well be fitted with head curved surface, influences accuracy of measurement, and two be the dynamics contacted with scalp also shadow of popping one's head in
Accuracy of measurement is rung, however, its uncontrollable contact force can bring discomfort to measured.Replaceable spy in Figure 16 E
Head-shield volume is big, is limited as probe consumptive material carrying amount, and waste of resource, does not meet the requirement of environmental protection.
● light source probe and detector probe are designed with electro-magnetic shielding cover, internal circuit realiration can be electromagnetically shielded, made
Detector is avoided by external interference.
● light source module, detector module and optical fiber/light source couples, the optical filtering of optical fiber/detector are integrated with coupling.This
Invention realizes coupling by using the probe 18,19 of integrated morphology.
● and two sonde configurations are simple, volume mass is small, convenient largely to be carried as low price consumptive material；Realize probe
Consumptive material convenient changing.
The replacing fibre-optical probe structure design that the present invention is made up of conical seat and fibre-optical probe realizes fibre-optical probe and consumed
The replacing of material, and light source probe is identical with the fibre-optical probe in detector probe, without distinguishing during replacing, can exchange.
And the probe cover (the 1600 of Figure 16 D and 16E) that United States Patent (USP) US8060189 need to be changed every time, the probe cover to complete simultaneously hide
The functions such as light, optical fiber mounting seat, sealing, complicated, volume is big, and as consumptive material, not only carrying amount is limited, and waste of resource,
The requirement of environmental protection is not met.
2. devise the light shield that can slide up and down
Up, testing staff can accurately judge connecing for fibre-optical probe and wounded's scalp to light shield during the present invention detection wounded
The situation of touching, after confirming that fibre-optical probe is contacted with wounded's scalp, promotes light shield, light shield is formed secretly with wounded head still further below
Room, blocks extraneous light entrance, interferometry.
Though United States Patent (USP) US8060189 also is provided with an opaque shade, expressed diaphragm system on its Fig. 4 A
It is similar to the application, but there is problem：Its light shield is fixed on base, and is to prevent that ambient from entering measurement
System, the length of light shield is more than the length of fibre-optical probe, so when detecting the wounded, due to the stop of light shield, causes medical matters
Personnel can not judge to pop one's head in whether push down the hair of the wounded, measurement is become unreliable.In order to solve this problem, the patent table
It is bright that shading is realized in the way of under its Fig. 4 B, i.e., metal or the light screening material of other materials directly on outer fiber set, so
Although avoiding the problem of upper figures of its figure C are present, when ambient light is stronger, because environment fibre-optical also contains
808nm near infrared light, directly or indirectly (from tissue scatter) may enter detector probe, form interference signal, influence is surveyed
Result is measured, equally measurement can be made to become unreliable.Therefore, in actual use, it is not used with the product that United States Patent (USP) is formed
Fig. 4 A mode, and require to avoid strong ambient light as far as possible in measurement, and require to live measuring point in measurement with stick shift,
Prevent ambient light from entering measuring system.
In being designed in the present invention using the structure of the nested metal tube of slidingtype light shield and outer fiber, it is to avoid this is asked
Topic, improves the degree of accuracy of measurement, and be easily achieved in structure.
3.LD light source pulse formula switch designs, light source itself radiated light energy greatly drop to before optimization (existing detector,
Including United States Patent (USP) US8060189) 6%, effectively reduce the power consumption of instrument, at the same improve measurement laser security.
Global design compact conformation, light and handy 4. complete machine is highly integrated, weight is containing two section AA battery only 500g, appearance and size
Only 135 × 65 × 80mm, consumptive material (fibre-optical probe) is small, conveniently can largely carry.
5. detection process fathoms as 3mm, noninvasive, quick, accurate, and does not need any reagent.It may be said that this equipment
Realized with simple and reliable structure and reached the former advanced level of the similar equipment of state, better than external similar production in certain this index
Product.The major parameter of several known detectors is relatively shown in Table 3.
The equipment technology performance comparison of table 3
| Crainscan | Inftrascanner1000 | Present invention equipment | |
| The place of production | The U.S. | The U.S. | Develop the country |
| Design form | Hand-held | Hand-held | Hand-held |
| Detection position | Volume, temporo, occipital lobe | Volume, temporo, top, occipital lobe | Volume, temporo, top, occipital lobe |
| Detection sensitivity | 88.5% | 88% | More than 90% |
| Detection specificity | 83.3% | 90.7% | More than 90% |
| It can detect that blood volume | -- | No more than 3.5ml | No more than 3.5ml |
| Detect depth | Subcutaneous 3cm | Subcutaneous 3.5cm | Subcutaneous 3.5cm |
| Detection time | 2min | 3min | 2min |
Claims (10)
1. device, including the detector sheet containing light source probe and detector probe are hindered in a kind of hand-held Near-infrared Brain hemotoncus inspection
Body, in addition to a light shield, it is characterised in that the detector body lower part sets slide-and-guide post, and light shield is by dark shading
Soft material is molded, and is the cover body to lower open mouth, is sleeved on detector sheet in vitro, light shield inside upper part is provided with and slide-and-guide
The sliding surface that post shapes match with size makes light shield realize relative motion with detector body to be socketed slide-and-guide post；
The light source probe and detector probe are each independent spring probe mechanism；The spring probe mechanism includes shielding
Cover, mounting seat, spring and conical seat and fibre-optical probe, wherein：
Radome is the cylindrical cavity with side open surface, and its upper end opens up the photoelectric cell that through hole is used to draw installing in mounting seat
Power supply and control line, lower end sets the bottom of evagination to be fixed with base, and radome bottom and base relative position are equipped with out
Mouthful；
Mounting seat is step-like hollow posts, is axially sleeved ikn in the cavity of radome and bottom passes through base, mounting seat is provided with platform
Rank convex tendon, its maximum outside diameter is equal with radome internal diameter, and bottom minimum outer diameter is equal with the opening of base so that mounting seat can
It is fixedly mounted on base；
Mounting seat upper end is relative to be provided with two certain length elongated holes, and its step convex tendon top is provided with sheathed spring on step, step,
The bottom of spring props up mounting seat design step convex tendon, and its drift is more than long hole length；
Conical seat is fixedly mounted on the bottom of mounting seat, and it has longitudinally mounted hole；
Fibre-optical probe is interspersed in fibre-optical probe mounting hole, installed in the bottom of mounting seat.
2. device according to claim 1, it is characterised in that detector body exterior is for ease of the hollow housing of gripping, shell
The slide-and-guide post outside dimensions of body hypomere certain length is slightly less than housing epimere peripheral dimension, with limit light shield move up away from
From；Housing lowermost end is provided with base, and base dimensions are slightly larger than the peripheral dimension of slide-and-guide post to limit moving down for light shield
Size；Base is equipped with the light source probe and detector probe extended downwardly from.
3. device according to claim 2, it is characterised in that when light shield moves up and down along along lead movable distance,
The Design of length of light shield is：It is set not block light source probe and detector probe at the top of slide-and-guide post, simultaneously
Darkroom can be formed when moving it to the bottom of slide-and-guide post well beyond two probes, and with head curved face contact.
4. device according to claim 3, it is characterised in that detector body interior be equipped with perpendicular to base two pieces are put down
Capable control board is left control board and right control board, the battery bin equipped with battery, and battery the two poles of the earth are connected into control
Circuit board processed；Light source probe and detector probe distribution are connected and probe tip extends downwardly from base with base.
5. device according to claim 4, it is characterised in that left control board, right control board, battery bin and
The epimere of light source probe and detector probe is closed in the space that housing and base are surrounded, and light source probe and detector are visited
Distance is 3-5cm, battery, circuit board and probe epimere electrical connection between first two tip.
6. according to any one of claim 1 to 5 described device, it is characterised in that mounting seat is step-like for downward size reduction
Hollow posts, are axially sleeved ikn in the cavity of radome and bottom passes through the opening of base, mounting seat design step convex tendon, its maximum
External diameter is equal with radome internal diameter, and bottom minimum outer diameter is equal with the opening of base, and mounting seat is fixedly mounted on base；
In upper end, be provided with two longitudinal directions has the elongated hole of certain length to mounting seat relatively, and its step convex tendon top is provided with step, step
Upper sheathed spring, the bottom of spring props up mounting seat design step convex tendon, and its drift is higher than the bottom of elongated hole；Radome
Relevant position be also provided with screw, spring bottom props up the step convex tendon of mounting seat, interim by spring with instrument or hand during installation
The elongated hole of top compression to mounting seat is following topmost, and can reserve the space of screw screw-in, and elongated hole 2- can be stretched into length
4mm screw is from radome screw screws in mounting seat elongated hole, and the height design of radome screw just makes position after screw screw-in
In elongated hole the top of mounting seat, pressuring spring is made spring have at the top of certain pre- elasticity, mounting seat and radome by screw
Top between there is a displacement to realize that mounting seat moves upward and downward elastically certain distance.
7. device according to claim 6, it is characterised in that from top to bottom installed in the mounting seat for installing light source probe
There are LD light source modules and a collimation lens, the distance of collimation lens and LD light source modules lower end is 1-4mm；Or, for installing detection
Accurate photodiode and optical filter are from top to bottom equipped with the mounting seat of device probe, the upper end of fibre-optical probe and optical filter are tight
Patch is installed.
8. device according to claim 7, it is characterised in that longitudinal hole is fibre-optical probe installation inside the conical seat
Hole, sets in its cylinder partial bottom and installs steel ball, bullet in two laterally inwardly tapered centre bores, centre bore from the inside to the outside respectively
Spring and jackscrew；
The fibre-optical probe is constituted and is integral by fibre-optical probe seat, optical fiber protective tube and optical fiber, and optical fiber is arranged in fiber optic protection
In pipe, optical fiber front end is hemisphere face and slightly forward extends out optical fiber protective tube, and optical fiber and optical fiber protective tube are fixed in fiber bench.
9. according to any one of claim 1-5 described device, it is characterised in that the detector body top sets display mould
Block, battery cabin cap, power switch and function button are fixed on position of this body side surface of detector suitable for operation or viewing；
Left control board, right control board, display module, power switch, function button, LD light source dies in detector body
The parts such as block, accurate photodiode, battery are electrically connected to form circuit control system, wherein right control board realizes system
Major control function, including the state of power switch, function button is detected, LD light source modules, display module etc. are entered
Row control；Left control board mainly realizes power supply and to accurate photodiode measurement data acquisition, left control board
DC/DC chips are connected with battery, and signal amplification circuit is connected with accurate photodiode, by accurate photodiode weak current
The amplification of signal is simultaneously converted into voltage signal；AD sampling A/D chips are connected with signal amplification circuit, by the simulation of amplifying circuit
Signal is converted to data signal, and sends a signal to right control board.
10. device according to claim 8, it is characterised in that the detector body top sets display module, battery compartment
Lid, power switch and function button are fixed on position of this body side surface of detector suitable for operation or viewing；
Left control board, right control board, display module, power switch, function button, LD light source dies in detector body
The parts such as block, accurate photodiode, battery are electrically connected to form circuit control system, wherein right control board realizes system
Major control function, including the state of power switch, function button is detected, LD light source modules, display module etc. are entered
Row control；Left control board mainly realizes power supply and to accurate photodiode measurement data acquisition, left control board
DC/DC chips are connected with battery, and signal amplification circuit is connected with accurate photodiode, by accurate photodiode weak current
The amplification of signal is simultaneously converted into voltage signal；AD sampling A/D chips are connected with signal amplification circuit, by the simulation of amplifying circuit
Signal is converted to data signal, and sends a signal to right control board.
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| CN201410717848.6A CN104434034B (en) | 2014-12-01 | 2014-12-01 | Device is hindered in a kind of hand-held Near-infrared Brain hemotoncus inspection |
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| CN201410717848.6A CN104434034B (en) | 2014-12-01 | 2014-12-01 | Device is hindered in a kind of hand-held Near-infrared Brain hemotoncus inspection |
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| CN105011907A (en) * | 2015-06-23 | 2015-11-04 | 南京航空航天大学 | Detection equipment for abdominal bleeding |
| WO2016210357A1 (en) * | 2015-06-24 | 2016-12-29 | Regents Of The University Of California | Flexible, non-invasive real-time hematoma monitoring system using near-infrared spectroscopy |
| WO2017201203A1 (en) | 2016-05-17 | 2017-11-23 | Rebound Therapeutics Corporation | Methods and devices for color detection to localize the blood mass of an intracerebral hematoma |
| WO2018058231A1 (en) * | 2016-09-28 | 2018-04-05 | Archeoptix Biomedical Inc. | Optical imaging device and cap |
| CN106618493B (en) * | 2016-11-28 | 2019-11-22 | 武汉资联虹康科技股份有限公司 | The probe fixing structure of near infrared spectrum cerebral function imaging device |
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