CN104415352A - 利福平的个体化安全优效用药监测方法 - Google Patents

利福平的个体化安全优效用药监测方法 Download PDF

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Publication number
CN104415352A
CN104415352A CN201310379510.XA CN201310379510A CN104415352A CN 104415352 A CN104415352 A CN 104415352A CN 201310379510 A CN201310379510 A CN 201310379510A CN 104415352 A CN104415352 A CN 104415352A
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Prior art keywords
rifampicin
urine sample
safe
effective
monitoring individual
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CN201310379510.XA
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English (en)
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商春霞
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Individual
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Priority to CN201310379510.XA priority Critical patent/CN104415352A/zh
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  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

一种能够随时随地监测、调整利福平用量的技术方案。根据人体代谢原理和利福平的药理特点，利用利福平的物理性质进行药量监测，可以实现不分年龄、性别，安全、优效用药，既保证了利福平的疗效，又避免了利福平对肝肾的毒副作用，而且操作简单。

Description

利福平的个体化安全优效用药监测方法
技术领域
本发明可以使利福平真正实现个体化安全优效用药，有效避免利福平对肝肾的毒副作用。
背景技术
目前，患者服用利福平都是按照药品说明书和(或)遵医嘱，并且一定要定期检测肝肾功能才能在一定程度上防止肝肾损害等毒副作用，费用较高而且需要患者经常奔波于医院。
发明内容
为了实现利福平安全、优效的个体化用药，本发明提出一种监测方法，本方法不仅操作简单，而且能有效避免利福平对肝肾的毒副作用，实现利福平安全、高效的个体化用药。
具体实施方式
本发明解决其技术问题所采用的技术方案是：患者首次按医嘱服用利福平后，每日晚上入睡前采集一次尿样(尿样一)，次日晨起后再取一次尿样(尿样二)，然后对比观察：如果尿样一、尿样二均有利福平特有的桔红色出现，则下调利福平用量；如果尿样一、尿样二都没有利福平特有的桔红色出现，则上调利福平用量；如果尿样一有利福平特有的桔红色出现，尿样二没有利福平特有的桔红色出现，利福平用量不做调整。

Claims (1)

1.根据权利要求，利福平的个体化安全优效用药监测方法，其特征是：每日通过两次观察尿样颜色，并且依据尿样颜色变化调整利福平的用量。
CN201310379510.XA 2013-08-19 2013-08-19 利福平的个体化安全优效用药监测方法 Pending CN104415352A (zh)

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CN201310379510.XA CN104415352A (zh) 2013-08-19 2013-08-19 利福平的个体化安全优效用药监测方法

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CN201310379510.XA CN104415352A (zh) 2013-08-19 2013-08-19 利福平的个体化安全优效用药监测方法

Publications (1)

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CN104415352A true CN104415352A (zh) 2015-03-18

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CN201310379510.XA Pending CN104415352A (zh) 2013-08-19 2013-08-19 利福平的个体化安全优效用药监测方法

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2596492C1 (ru) * 2015-07-02 2016-09-10 Федеральное Государственное Бюджетное Учреждение "Новосибирский научно-исследовательский институт туберкулеза" Минздрава России (ФГБУ "ННИИТ" Минздрава России) Способ определения степени нарушения функции почек

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
宋金春: "《抗微生物药物学》", 31 October 2010 *
苗积生等: "尿中利福平排泄情况分析", 《医院药学杂志》 *
魏茂: "《临床药品手册》", 31 March 2013 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2596492C1 (ru) * 2015-07-02 2016-09-10 Федеральное Государственное Бюджетное Учреждение "Новосибирский научно-исследовательский институт туберкулеза" Минздрава России (ФГБУ "ННИИТ" Минздрава России) Способ определения степени нарушения функции почек

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Application publication date: 20150318