CN104415207A - Traditional Chinese medicine for treating nephritis and preparation method of traditional Chinese medicine - Google Patents
Traditional Chinese medicine for treating nephritis and preparation method of traditional Chinese medicine Download PDFInfo
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- CN104415207A CN104415207A CN201310401935.6A CN201310401935A CN104415207A CN 104415207 A CN104415207 A CN 104415207A CN 201310401935 A CN201310401935 A CN 201310401935A CN 104415207 A CN104415207 A CN 104415207A
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Abstract
The invention provides a traditional Chinese medicine for treating nephritis and a preparation method of the traditional Chinese medicine. The traditional Chinese medicine preparation comprises cape jasmine fruits, barbary wolfberry fruits, liquorice root, membranous milkvetch root, red paeony root, rehmannia root and other medicaments, and is prepared into capsules or tablets by crushing, extracting, concentrating and drying. The traditional Chinese medicine for treating nephritis, prepared by the invention, has the effects of clearing heat, cooling blood, nourishing yin and nourishing the kidneys, and the medicine has the advantages of high safety performance, stable quality, reliability, low cost and convenience in carrying and storage, is in line with large-scale production demands of an enterprise in the current stage and has great market development prospects.
Description
Technical field
The invention belongs to technical field of medicine, relate to a kind of Chinese medicine being used for the treatment of nephritis and preparation method thereof.
Background technology
Glomerulonephritis is a kind of immune disease, being the one group of immune disease that clinical manifestation is similar, pathological change differs, prognosis is not quite similar being primary in glomerule caused by many reasons, is its feature with albuminuria, hematuria, edema, hypertension and renal insufficiency.The feature of primary disease is that onset is hidden, the course of disease is tediously long.Bring inconvenience and misery to patient, for alleviating the misery of ailing person, it is imperative for carrying out improvement raising to existing active drug medicine, also quick and safe the most.
CN1054981C Chinese invention patent discloses shenyankangfu tablet and preparation method thereof, it is characterized in that being made up of, through pulverizing, extracting, concentrate, make tablet medicines such as the Cortex Eucommiae, Radix Salviae Miltiorrhizae, Hedyotidis Diffusaes.Be used for the treatment of nephritis, the effective percentage of chronic glomerulonephritis is 80%, wherein cure rate is 64%.
CN101979058B Chinese invention patent discloses a kind of Chinese medicine for the treatment of chronic nephritis, it is characterized in that 16 taste herbal medicine immersions such as Fructus Citri Sarcodactylis, Fructus Quisqualis, Herba Leonuri, Radix Salviae Miltiorrhizae, Rhizoma Polygonatis, decoct after twice medicinal liquid is merged, be equally divided into two parts, sooner or later respectively take portion.This invention have carry inconvenience, take inconvenience etc. shortcoming.
CN102210780B Chinese invention patent discloses a kind of Chinese medicine for the treatment of chronic nephritis, it is characterized in that 12 taste herbal medicine immersions such as Cordyceps, Radix Dipsaci, the Cortex Eucommiae, Flos Carthami, Radix Scrophulariae, Cornu Bubalis, decocts rear oral liquid medicine.This invention have cost high, decoct operation numerous and diverse, carry inconvenience, take inconvenience etc. shortcoming.
Summary of the invention
The present invention aims to provide one, and to have security performance high, good effect, steady quality, reliable, with low cost, is easy to carry and Chinese medicine being used for the treatment of nephritis stored and preparation method thereof.
The Chinese medicine being used for the treatment of nephritis provided by the invention is prepared from by the medical material of following weight ratio:
Fructus Gardeniae 3 ~ 5 parts of Rhizoma Chuanxiongs 1 ~ 2 part of Radix Angelicae Sinensis 3 ~ 5 portions of Herba Ecliptaes 4 ~ 6 portions of Radix Rehmanniae 3 ~ 5 parts
2 ~ 3 parts, Cornu Cervi Pantotrichum 1 ~ 3 part of Radix Astragali 3 ~ 5 parts of Radix Platycodoniss 2 ~ 3 parts of Radix Morindae Officinaliss 4 ~ 6 portions of Radix Glycyrrhizaes
Radix Paeoniae Rubra 2 ~ 3 parts of Poria 3 ~ 5 portions of Radix Sanguisorbaes 8 ~ 10 parts of Semen Cuscutae 5 ~ 7 portions of Rhizoma Dioscoreaes 5 ~ 7 parts
Fructus Lycii 5 ~ 7 parts of Radix Polygoni Multiflori 10 ~ 12 parts
Above-described a kind of Chinese medicinal preparation method being used for the treatment of nephritis comprises the steps:
fructus Gardeniae, Rhizoma Chuanxiong, Radix Angelicae Sinensis oven dry are pulverized for subsequent use;
by all the other Herba Ecliptae, Radix Rehmanniae etc. 14 taste, decoct with water secondary, first time adds water 10 times amount, decoct 3 hours, add water 5 ~ 8 times amount for the second time, decocts 2 hours, collecting decoction, filter, filtrate is condensed into the thick paste that relative density is 1.30 ~ 1.35 (60 DEG C);
add the fine powders such as above-mentioned Radix Angelicae Sinensis, mixing, 50-60 DEG C dry, pulverize into fine powder;
make capsule or tablet as required.
A kind of Chinese medicine being used for the treatment of nephritis of the present invention and preparation method thereof, is characterized in that baking temperature is 60 DEG C.
Nature and flavor and the effect of medical material involved by Chinese medicine of the present invention are as follows:
Fructus Gardeniae, another name Yellow Fructus Gardeniae, Fructus Gardeniae, white toad, abnormal smells from the patient, bitter, cold, nontoxic.There is pathogenic fire purging relieving restlessness; Clearing away heat-damp and promoting diuresis; Removing pathogenic heat from blood and toxic substance from the body; Fructus Gardeniae Preparatus: cooling blood for hemostasis effect.Cure mainly calentura vexed; Liver-fire conjunctival congestion; Headache; Jaundice due to damp-heat; Stranguria; Dysentery hematuria; Aphtha of the mouth and tongue; Sore swollen toxin; Sprain and swell and ache.
Rhizoma Chuanxiong, original name rhizome of chuanxiong Qiong, acrid in the mouth, warm in nature.Return liver, gallbladder, pericardium channel.There is blood circulation promoting and blood stasis dispelling; Activating QI to alleviate the depression; Wind-expelling pain-stopping effect.
Radix Angelicae Sinensis, sweet in the mouth; Pungent; Bitter; Warm in nature, return liver; The heart; Spleen channel, has and enriches blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation effect.
Herba Ecliptae, sweet, sour, cold.Return kidney, Liver Channel.Nourishing the liver and kidney, cooling blood for hemostasis.For odontoseisis, early whitening of beard and hair, vertigo and tinnitus, the acid of waist knee joint, YinXuXueRe, haematemesis, blood nosebleed, hematuria, dysentery, metrostaxis, traumatic hemorrhage.
Radix Rehmanniae, is divided on medical material according to concocting method: Radix Rehmanniae, Radix Rehmanniae and Radix Rehmanniae Preparata, and its property of medicine and effect also have larger difference simultaneously, according to " China's book on Chinese herbal medicine " effect classification: Radix Rehmanniae is heat removing and blood cooling medicine; Radix Rehmanniae Preparata is then tonic.
Cornu Cervi Pantotrichum, sweet, salty, temperature.Return kidney, Liver Channel.Invigorating kidney-YANG, mends marrow, bone and muscle strengthening, adjusts punching to appoint, holder sore effect.
The Radix Astragali, has another name called Radix Astragali, is the general designation of plant and Chinese crude drug.There is the effects such as invigorating QI to consolidate the body surface resistance, diuretic detumescent, expelling pus and toxin by strengthening QI, granulation promoting
Radix Platycodonis, bitter in the mouth; Pungent; Property flat, lung qi dispersing, eliminate the phlegm, sore-throat relieving, evacuation of pus, sharp the five internal organs, fill blood, mend five kinds of over strain, effect of fostering the spirit of nobility.
Radix Morindae Officinalis, pungent, sweet, tepor.Return liver; Kidney channel.Reinforcing the kidney and supporting YANG; Expelling wind and removing dampness; Bone and muscle strengthening effect.
Radix Glycyrrhizae, sweet in the mouth, property is put down, nontoxic.Treating disorders in five ZANG-organs six internal organs cold and heat pathogen, hard muscles and bones, longue meat, times strength, removing toxic substances, clothes are made light of one's life by commiting suicide and are prolonged life for a long time.Raw by pathogenic fire purging heat, ripe use is fallen apart exterior cold, goes pharyngalgia, except pathogenic heat, and slow healthy energy, yin nourishing blood, tonifying the spleen and stomach, lung moistening.
Radix Paeoniae Rubra, bitter, be slightly cold.Return Liver Channel.Clots absorbing, pain relieving, removing heat from blood, detumescence.Cure mainly: control the stagnant amenorrhea of the stasis of blood, hernia abdominal mass is gathered, suffer from abdominal pain, hypochondriac pain, epistaxis, dysentery, discharging fresh blood stool, conjunctival congestion, carbuncle, injury from falling down.
Poria, is commonly called as Poria, Song Ling, Poria, nature and flavor: sweet, light, flat.Gui Jing: GUIXIN warp, lung meridian, spleen channel, kidney channel.Function: diuretic medicine; Diuretics with the action of eliminating dampness.
Radix Sanguisorbae, picric acid; Cold; Nontoxic, return liver; Lung; Kidney; Large intestine channel, has cooling blood for hemostasis, heat-clearing and toxic substances removing, detumescence sore effect.
Semen Cuscutae, sweet, temperature.Return liver,kidney,spleen warp.Nourishing the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, antiabortive, improving eyesight, antidiarrheal.For impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness of the waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, frequent fetal movement, spleen is suffered from a deficiency of the kidney and is rushed down; Externally treating leucoderma.
Rhizoma Dioscoreae, sweet in the mouth, property is put down.Return spleen, lung, kidney channel.Spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission.
Fructus Lycii, sweet, flat.There is nourishing the liver, nourishing kidney, lung moistening effect.
Radix Polygoni Multiflori is bitter; Sweet; Puckery; Slightly warm in nature.Return liver; Kidney channel, system is used: enrich and benefit essence and blood; Raw use: removing toxic substances, preventing the attack (or recurrence) of malaria, loosening bowel to relieve constipation.
Product obtained by the present invention has clearing away heat and cooling blood, and YIN nourishing supports kidney effect, and drug safety performance is high, steady quality, reliable, with low cost, is easy to carry and storage, meets present stage enterprise scale Production requirement, have the prospect of marketing.
detailed description of the inventionenforcement below can illustrate in greater detail the present invention, but does not limit the present invention in any form.
embodiment 1
Prescription:
Fructus Gardeniae 45 g Rhizoma Chuanxiong 15 g Radix Angelicae Sinensis 45 g Herba Ecliptae 72 g Radix Rehmanniae 45 g
The Cornu Cervi Pantotrichum 20 g Radix Astragali 45 g Radix Platycodonis 30 g Radix Morindae Officinalis 72 g Radix Glycyrrhizae 30 g
Radix Paeoniae Rubra 30 g Poria 45 g Radix Sanguisorbae 145 g Semen Cuscutae 80 g Rhizoma Dioscoreae 80 g
Fructus Lycii 80 g Radix Polygoni Multiflori 172 g
Preparation method:
fructus Gardeniae, Rhizoma Chuanxiong, Radix Angelicae Sinensis oven dry are pulverized for subsequent use;
by all the other Herba Ecliptae, Radix Rehmanniae etc. 14 taste, decoct with water secondary, first time adds water 10 times amount, decoct 3 hours, add water 8 times amount for the second time, decocts 2 hours, collecting decoction, filter, filtrate is condensed into the thick paste that relative density is 1.30 ~ 1.35 (60 DEG C);
add the fine powders such as above-mentioned Radix Angelicae Sinensis, mixing, 60 DEG C dry, pulverize into fine powder;
add 4% carboxymethylstach sodium by weight, granulate with appropriate 10% starch slurry, 60 DEG C of dry 1.5h, 24 mesh sieve granulate;
additional 4% carboxymethylstach sodium, 1% magnesium stearate, fill is in No. 0 capsule, and every 0.28g, to obtain final product.
embodiment 2
Prescription:
Fructus Gardeniae 45 g Rhizoma Chuanxiong 15 g Radix Angelicae Sinensis 45 g Herba Ecliptae 72 g Radix Rehmanniae 45 g
The Cornu Cervi Pantotrichum 20 g Radix Astragali 45 g Radix Platycodonis 30 g Radix Morindae Officinalis 72 g Radix Glycyrrhizae 30 g
Radix Paeoniae Rubra 30 g Poria 45 g Radix Sanguisorbae 145 g Semen Cuscutae 80 g Rhizoma Dioscoreae 80 g
Fructus Lycii 80 g Radix Polygoni Multiflori 172 g
Preparation method:
fructus Gardeniae, Rhizoma Chuanxiong, Radix Angelicae Sinensis oven dry are pulverized for subsequent use;
by all the other Herba Ecliptae, Radix Rehmanniae etc. 14 taste, decoct with water secondary, first time adds water 10 times amount, decoct 3 hours, add water 6 times amount for the second time, decocts 2 hours, collecting decoction, filter, filtrate is condensed into the thick paste that relative density is 1.30 ~ 1.35 (60 DEG C);
add the fine powders such as above-mentioned Radix Angelicae Sinensis, mixing, 60 DEG C dry, pulverize into fine powder;
add 25% pregelatinized Starch, 4% carboxymethylstach sodium, 3% hydroxypropyl methylcellulose by weight, granulate with appropriate 15% starch slurry, 60 DEG C of dry 1.5h, 18 mesh sieve granulate;
additional 4% carboxymethylstach sodium, 1% magnesium stearate, 8mm scrobicula circular die tabletting, every sheet 0.28g;
get it filled with film-coating premixing auxiliary material (gastric solubility) add appropriate 80% ethanol mixing after coating, film-coat layer weightening finish 3% ~ 5%, to obtain final product.
embodiment 3
Prescription:
Fructus Gardeniae 45 g Rhizoma Chuanxiong 15 g Radix Angelicae Sinensis 45 g Herba Ecliptae 72 g Radix Rehmanniae 45 g
The Cornu Cervi Pantotrichum 20 g Radix Astragali 45 g Radix Platycodonis 30 g Radix Morindae Officinalis 72 g Radix Glycyrrhizae 30 g
Radix Paeoniae Rubra 30 g Poria 45 g Radix Sanguisorbae 145 g Semen Cuscutae 80 g Rhizoma Dioscoreae 80 g
Fructus Lycii 80 g Radix Polygoni Multiflori 172 g
Preparation method:
fructus Gardeniae, Rhizoma Chuanxiong, Radix Angelicae Sinensis oven dry are pulverized for subsequent use;
by all the other Herba Ecliptae, Radix Rehmanniae etc. 14 taste, decoct with water secondary, first time adds water 10 times amount, decoct 3 hours, add water 8 times amount for the second time, decocts 2 hours, collecting decoction, filter, filtrate is condensed into the thick paste that relative density is 1.30 ~ 1.35 (60 DEG C);
add the fine powders such as above-mentioned Radix Angelicae Sinensis, mixing, 60 DEG C dry, pulverize into fine powder;
add 30% pregelatinized Starch, 4% carboxymethylstach sodium by weight, with appropriate 70% alcohol granulation, 60 DEG C of dry 1.5h, 18 mesh sieve granulate;
additional 3% carboxymethylstach sodium, 1% magnesium stearate, 8mm scrobicula circular die tabletting, every sheet 0.28g;
get it filled with film-coating premixing auxiliary material (gastric solubility) add appropriate 80% ethanol mixing after coating, film-coat layer weightening finish 3% ~ 5%, to obtain final product.
Claims (4)
1. Chinese medicine being used for the treatment of nephritis and preparation method thereof, is characterized in that, is prepared from by the medical material of following weight ratio:
Fructus Gardeniae 3 ~ 5 parts of Rhizoma Chuanxiongs 1 ~ 2 part of Radix Angelicae Sinensis 3 ~ 5 portions of Herba Ecliptaes 4 ~ 6 portions of Radix Rehmanniae 3 ~ 5 parts
2 ~ 3 parts, Cornu Cervi Pantotrichum 1 ~ 3 part of Radix Astragali 3 ~ 5 parts of Radix Platycodoniss 2 ~ 3 parts of Radix Morindae Officinaliss 4 ~ 6 portions of Radix Glycyrrhizaes
Radix Paeoniae Rubra 2 ~ 3 parts of Poria 3 ~ 5 portions of Radix Sanguisorbaes 8 ~ 10 parts of Semen Cuscutae 5 ~ 7 portions of Rhizoma Dioscoreaes 5 ~ 7 parts
Fructus Lycii 5 ~ 7 parts of Radix Polygoni Multiflori 10 ~ 12 parts.
2. a kind of Chinese medicine being used for the treatment of nephritis according to claim 1 and preparation method thereof, it is characterized in that, preparation method comprises the steps:
fructus Gardeniae, Rhizoma Chuanxiong, Radix Angelicae Sinensis oven dry are pulverized for subsequent use;
by all the other Herba Ecliptae, Radix Rehmanniae etc. 14 taste, decoct with water secondary, first time adds water 10 times amount, decocts 3 hours, and second time adds water 5 ~ 8 times amount, and decoct 2 hours, collecting decoction, filtration, filtrate is condensed into thick paste;
add the fine powders such as above-mentioned Radix Angelicae Sinensis, mixing, 50-65 DEG C dry, pulverize into fine powder;
make capsule or tablet as required.
3. a kind of Chinese medicine being used for the treatment of nephritis according to claim 2 and preparation method thereof, is characterized in that the method step
the relative density of thick paste is 1.30 ~ 1.35 (60 DEG C).
4. a kind of Chinese medicine being used for the treatment of nephritis according to claim 2 and preparation method thereof, is characterized in that the method step
baking temperature is 60 DEG C.
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