CN104399302A - Multi-layer filtering device used for separation and purification of biological pharmacy - Google Patents
Multi-layer filtering device used for separation and purification of biological pharmacy Download PDFInfo
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- CN104399302A CN104399302A CN201410674254.1A CN201410674254A CN104399302A CN 104399302 A CN104399302 A CN 104399302A CN 201410674254 A CN201410674254 A CN 201410674254A CN 104399302 A CN104399302 A CN 104399302A
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Abstract
The invention provides a multi-layer filtering device used for separation and purification of biological pharmacy, wherein the multi-layer filtering device can make better use of biological raw materials. The multi-layer filtering device comprises a casing (1), an installation table (6) is arranged on the casing (1) and is equipped with a material inlet pipe (2) downwards inserted into the casing (1), and the material inlet pipe (2) is connected with a first-level filtering film (3), a second-level filtering film (4) and a third-level filtering film (5) from inside to outside sequentially; each of the three filtering films is provided with a spherical structure formed by assembling two hemi-spherical structures, filtration apertures of the three filtering films are gradually reduced from inside to outside, and the material inlet pipe (2) directly penetrates into the first-level filtering film (3) with a smallest diameter; a sealing connector (10) is arranged on the connection portion of the material inlet pipe (2) and each filtering film; a liquid outlet pipe (7) is further arranged at the bottom of the casing (1) and is further provided with a flow control valve (8); an electric control tap valve (13) is arranged at the bottom of each filtering film.
Description
Technical field
The present invention relates to a kind of production equipment for bio-pharmaceuticals, specifically refer to a kind of multi-layer filtrating equipment of the separation and purification for bio-pharmaceuticals.
Background technology
Bio-pharmaceuticals raw material, based on natural biomaterial, comprises microorganism, human body, animal, plant, marine organisms etc.Along with the development of biotechnology, the biological raw material having object manually to obtain becomes the main source of current biological pharmaceutical raw material.As obtain with immunization animal material, change the obtained microorganism of gene structure or other cell materials etc.The feature of bio-pharmaceutical is that pharmacologically active is high, toxic and side effect is little, is of high nutritive value.Bio-pharmaceutical mainly contains protein, nucleic acid, carbohydrate, lipid etc.The component units of these materials is amino acid, nucleotides, monose, aliphatic acid etc., not only harmless but also be important nutriment to human body.In bio-pharmaceuticals process, have the step that important, i.e. separation and purification, so-called separation and purification is exactly by technological means such as filtrations by the separating substances such as specific protein, nucleic acid, carbohydrate, lipid in biological raw material out.
Separation and purification device category of the prior art is various, but be the structure adopting one-level formula to be separated mostly, namely direct by biological raw material by one deck filter membrane, filtered by other different from the material of required purification for molecular size molecules, be namely left is required material.This structure has individual weak point, is exactly at the bottom of the utilization rate of raw material, and in prior art, biological raw material is the mixture of the materials such as protein, nucleic acid, carbohydrate, lipid mostly, if directly filter out protein, other mixed material has just been wasted.Also but if the materials such as nucleic acid, carbohydrate, lipid can be separated one by one while filtration protein, just substantially increase the utilization rate of filter to biological raw material.
In sum, at present, a kind of filter of the separation and purification for bio-pharmaceuticals higher to the utilization rate of biological raw material is badly in need of.
Summary of the invention
The technical problem to be solved in the present invention is, provides a kind of multi-layer filtrating equipment of the separation and purification for bio-pharmaceuticals higher to the utilization rate of biological raw material.
For solving the problems of the technologies described above, technical scheme provided by the invention is: a kind of multi-layer filtrating equipment of the separation and purification for bio-pharmaceuticals, it comprises a housing, described housing is provided with an erecting bed, erecting bed is provided with a feed pipe inserted in housing downwards, described feed pipe is from inside to outside connected with first order filter membrane, second level filter membrane and third level filter membrane in turn; The chondritic of above-mentioned three filter membranes all for being assembled into by two semiglobes, and the pore size filter size of three filter membranes is from inside to outside successively decreased, described feed pipe is through in the minimum first order filter membrane of diameter; The junction of described feed pipe and each filter membrane is provided with seal nipple; The bottom of housing is also provided with drain pipe, and drain pipe is also provided with flow control valve; The bottom of each filter membrane is provided with an automatically controlled bleeder valve.
As improvement, the top of described housing is also provided with the pressure balance mouth for being connected with hull outside.
As improvement, after described flow control valve, be also provided with drawing liquid pump.
As improvement, the bottom of described housing is also provided with ultrasonic oscillator.
As improvement, described automatically controlled bleeder valve is the wireless remote control magnetic valve of internal battery.
After adopting said structure, the present invention has following beneficial effect: it comprises a housing, described housing is provided with an erecting bed, erecting bed is provided with a feed pipe inserted in housing downwards, described feed pipe is from inside to outside connected with first order filter membrane, second level filter membrane and third level filter membrane in turn; The chondritic of above-mentioned three filter membranes all for being assembled into by two semiglobes, and the pore size filter size of three filter membranes is from inside to outside successively decreased, described feed pipe is through in the minimum first order filter membrane of diameter; The junction of described feed pipe and each filter membrane is provided with seal nipple; The bottom of housing is also provided with drain pipe, and drain pipe is also provided with flow control valve; The bottom of each filter membrane is provided with an automatically controlled bleeder valve.Multiple filtration film adopts the design of one deck bag one deck of onion formula, space is large intensive again, biological raw material is imported to the first order filter membrane of innermost layer by feed pipe, then successively filter, the molecule of different size is separated to respectively in different filter membranes, then outermost small-molecule substance is first derived by the drain pipe of bottom, and then the material derivation in third level filter membrane is deposited by automatically controlled bleeder valve that remote control is opened bottom third level filter membrane in addition, the material in all filter membranes is derived by one-level one-level like this respectively.And then restart new one and take turns filtration.
The top of described housing is also provided with the pressure balance mouth for being connected with hull outside.Balance port can allow the pressure in housing keep balance, makes fluid more smooth and easy.Also drawing liquid pump is provided with after described flow control valve.Drawing liquid pump can increase the efficiency of fluid.The bottom of described housing is also provided with ultrasonic oscillator.Ultrasonic oscillator can by vibration effectively remove each filter membrane adheres to affect filter membrane by useless materials such as the impurity of performance, described automatically controlled bleeder valve is the wireless remote control magnetic valve of internal battery.Remote control magnetic valve is more convenient to control, simultaneously also minimum for the impact of filter membrane.
In sum, the invention provides a kind of multi-layer filtrating equipment of the separation and purification for bio-pharmaceuticals higher to the utilization rate of biological raw material.
Accompanying drawing explanation
Fig. 1 is the structural representation for the multi-layer filtrating equipment of the separation and purification of bio-pharmaceuticals in the present invention.
As shown in the figure: 1, housing, 2, feed pipe, 3, first order filter membrane, 4, second level filter membrane, 5, third level filter membrane, 6, erecting bed, 7, drain pipe, 8, flow control valve, 9, drawing liquid pump, 10, seal nipple, 11, ultrasonic oscillator, 12, pressure balance mouth, 13, automatically controlled bleeder valve.
Detailed description of the invention
Below in conjunction with accompanying drawing, the present invention is described in further detail.
By reference to the accompanying drawings 1, a kind of multi-layer filtrating equipment of the separation and purification for bio-pharmaceuticals, it comprises a housing 1, described housing 1 is provided with an erecting bed 6, erecting bed 6 is provided with a feed pipe 2 inserted in housing 1 downwards, described feed pipe 2 is from inside to outside connected with first order filter membrane 3, second level filter membrane 4 and third level filter membrane 5 in turn; The chondritic of above-mentioned three filter membranes all for being assembled into by two semiglobes, and the pore size filter size of three filter membranes is from inside to outside successively decreased, described feed pipe 2 is through in the minimum first order filter membrane 3 of diameter; Described feed pipe 2 is provided with seal nipple 10 with the junction of each filter membrane; The bottom of housing 1 is also provided with drain pipe 7, and drain pipe 7 is also provided with flow control valve 8; The bottom of each filter membrane is provided with an automatically controlled bleeder valve 13.
As improvement, the top of described housing 1 is also provided with the pressure balance mouth 12 for being connected with hull outside.
As improvement, after described flow control valve 8, be also provided with drawing liquid pump 9.
As improvement, the bottom of described housing 1 is also provided with ultrasonic oscillator 11.
As improvement, described automatically controlled bleeder valve 13 is the wireless remote control magnetic valve of internal battery.
After adopting said structure, the present invention has following beneficial effect: it comprises a housing 1, described housing 1 is provided with an erecting bed 6, erecting bed 6 is provided with a feed pipe 2 inserted in housing 1 downwards, described feed pipe 2 is from inside to outside connected with first order filter membrane 3, second level filter membrane 4 and third level filter membrane 5 in turn; The chondritic of above-mentioned three filter membranes all for being assembled into by two semiglobes, and the pore size filter size of three filter membranes is from inside to outside successively decreased, described feed pipe 2 is through in the minimum first order filter membrane 3 of diameter; Described feed pipe 2 is provided with seal nipple 10 with the junction of each filter membrane; The bottom of housing 1 is also provided with drain pipe 7, and drain pipe 7 is also provided with flow control valve 8; The bottom of each filter membrane is provided with an automatically controlled bleeder valve 13.Multiple filtration film adopts the design of one deck bag one deck of onion formula, space is large intensive again, biological raw material is imported to the first order filter membrane 3 of innermost layer by feed pipe, then successively filter, the molecule of different size is separated to respectively in different filter membranes, then outermost small-molecule substance is first derived by the drain pipe of bottom, and then the material derivation in third level filter membrane is deposited by automatically controlled bleeder valve that remote control is opened bottom third level filter membrane in addition, the material in all filter membranes is derived by one-level one-level like this respectively.And then restart new one and take turns filtration.
The top of described housing 1 is also provided with the pressure balance mouth 12 for being connected with hull outside.Balance port can allow the pressure in housing keep balance, makes fluid more smooth and easy.Drawing liquid pump 9 is also provided with after described flow control valve 8.Drawing liquid pump can increase the efficiency of fluid.The bottom of described housing 1 is also provided with ultrasonic oscillator 11.Ultrasonic oscillator can by vibration effectively remove each filter membrane adheres to affect filter membrane by useless materials such as the impurity of performance, described automatically controlled bleeder valve 13 is the wireless remote control magnetic valve of internal battery.Remote control magnetic valve is more convenient to control, simultaneously also minimum for the impact of filter membrane.
In sum, the invention provides a kind of multi-layer filtrating equipment of the separation and purification for bio-pharmaceuticals higher to the utilization rate of biological raw material.
Be described the present invention and embodiment thereof above, this description does not have restricted, and shown in accompanying drawing is also one of embodiments of the present invention, and actual structure is not limited thereto.If generally speaking those of ordinary skill in the art enlightens by it, when not departing from the invention aim, designing the frame mode similar to this technical scheme and embodiment without creationary, all should protection scope of the present invention be belonged to.
Claims (5)
1. the multi-layer filtrating equipment for the separation and purification of bio-pharmaceuticals, it is characterized in that: it comprises a housing (1), described housing (1) is provided with an erecting bed (6), erecting bed (6) is provided with a feed pipe (2) inserted in housing (1) downwards, described feed pipe (2) is from inside to outside connected with first order filter membrane (3), second level filter membrane (4) and third level filter membrane (5) in turn; The chondritic of above-mentioned three filter membranes all for being assembled into by two semiglobes, and the pore size filter size of three filter membranes is from inside to outside successively decreased, described feed pipe (2) is through in the minimum first order filter membrane (3) of diameter; Described feed pipe (2) is provided with seal nipple (10) with the junction of each filter membrane; The bottom of housing (1) is also provided with drain pipe (7), drain pipe (7) is also provided with flow control valve (8); The bottom of each filter membrane is provided with an automatically controlled bleeder valve (13).
2. the multi-layer filtrating equipment of the separation and purification for bio-pharmaceuticals according to claim 1, is characterized in that: the top of described housing (1) is also provided with the pressure balance mouth (12) for being connected with hull outside.
3. the multi-layer filtrating equipment of the separation and purification for bio-pharmaceuticals according to claim 1, is characterized in that: be also provided with drawing liquid pump (9) after described flow control valve (8).
4. the multi-layer filtrating equipment of the separation and purification for bio-pharmaceuticals according to claim 1, is characterized in that: the bottom of described housing (1) is also provided with ultrasonic oscillator (11).
5. the multi-layer filtrating equipment of the separation and purification for bio-pharmaceuticals according to claim 1, is characterized in that: described automatically controlled bleeder valve (13) is the wireless remote control magnetic valve of internal battery.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410674254.1A CN104399302A (en) | 2014-11-21 | 2014-11-21 | Multi-layer filtering device used for separation and purification of biological pharmacy |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410674254.1A CN104399302A (en) | 2014-11-21 | 2014-11-21 | Multi-layer filtering device used for separation and purification of biological pharmacy |
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| CN104399302A true CN104399302A (en) | 2015-03-11 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201410674254.1A Pending CN104399302A (en) | 2014-11-21 | 2014-11-21 | Multi-layer filtering device used for separation and purification of biological pharmacy |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106075984A (en) * | 2016-08-08 | 2016-11-09 | 燕京啤酒(玉林)有限公司 | A kind of defecator of beer bottle washing machine heater |
| CN111804060A (en) * | 2020-07-24 | 2020-10-23 | 新昌县以琳环保科技有限公司 | Waste water double-circulation multi-bin filtering treatment device |
| CN114112560A (en) * | 2021-12-14 | 2022-03-01 | 海南昊霖环保科技有限公司 | Hierarchical sampling method and device for air monitoring |
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| CN1526468A (en) * | 2003-03-06 | 2004-09-08 | 许永德 | Multilayer filter |
| CN101249341A (en) * | 2008-03-28 | 2008-08-27 | 枣庄矿业（集团）有限责任公司柴里煤矿 | Bounce-back type multilevel water flush purifier |
| CN103301647A (en) * | 2013-06-28 | 2013-09-18 | 广西运亨酒业有限公司 | Alcohol steam recycling device |
| CN203750263U (en) * | 2014-03-18 | 2014-08-06 | 江苏李文甲化工有限公司 | Multi-layered filtering device for mixed paint |
| CN204319901U (en) * | 2014-11-21 | 2015-05-13 | 成都彼斯特生物科技有限公司 | For the multi-layer filtrating equipment of the separation and purification of bio-pharmaceuticals |
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2014
- 2014-11-21 CN CN201410674254.1A patent/CN104399302A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1526468A (en) * | 2003-03-06 | 2004-09-08 | 许永德 | Multilayer filter |
| CN101249341A (en) * | 2008-03-28 | 2008-08-27 | 枣庄矿业（集团）有限责任公司柴里煤矿 | Bounce-back type multilevel water flush purifier |
| CN103301647A (en) * | 2013-06-28 | 2013-09-18 | 广西运亨酒业有限公司 | Alcohol steam recycling device |
| CN203750263U (en) * | 2014-03-18 | 2014-08-06 | 江苏李文甲化工有限公司 | Multi-layered filtering device for mixed paint |
| CN204319901U (en) * | 2014-11-21 | 2015-05-13 | 成都彼斯特生物科技有限公司 | For the multi-layer filtrating equipment of the separation and purification of bio-pharmaceuticals |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106075984A (en) * | 2016-08-08 | 2016-11-09 | 燕京啤酒(玉林)有限公司 | A kind of defecator of beer bottle washing machine heater |
| CN111804060A (en) * | 2020-07-24 | 2020-10-23 | 新昌县以琳环保科技有限公司 | Waste water double-circulation multi-bin filtering treatment device |
| CN114112560A (en) * | 2021-12-14 | 2022-03-01 | 海南昊霖环保科技有限公司 | Hierarchical sampling method and device for air monitoring |
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Application publication date: 20150311 |