CN104381300A - Efficient compound type bactericide and production method thereof - Google Patents
Efficient compound type bactericide and production method thereof Download PDFInfo
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- CN104381300A CN104381300A CN201410710761.6A CN201410710761A CN104381300A CN 104381300 A CN104381300 A CN 104381300A CN 201410710761 A CN201410710761 A CN 201410710761A CN 104381300 A CN104381300 A CN 104381300A
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Abstract
The invention belongs to the technical field of designing and preparing industrial water treatment reagents, and in particular relates to an efficient compound type bactericide and a production method thereof. The invention provides the efficient bactericide suitable for an industrial circulating water cooling system, the bactericide has the characteristics of being high in bactericidal efficiency, low in drug resistance and wide in applicable range, and the production method is simple and reasonable, the production cost of an enterprise can be maximally lowered. The bactericide disclosed by the invention is prepared from the following raw materials in percent by weight: 5-15% of 2,2-dibromo-3-cyanopropionamide, 3-8% of polyoxyethylene soybean oil acyl amine, 10-20% of glycol, 3-8% of 10% sulfuric acid, 5-15% of isothiazolinone, 3-8% of CuSO4, and the balance being distilled water.
Description
Technical field
The invention belongs to the Design & preparation technical field of Treatment of Industrial Water chemical reagent, particularly relate to a kind of efficient compound bactericide and production method thereof.
Background technology
Along with developing rapidly of China's economy, improving constantly of industrialized level, updating of large industry equipment, the use of a large amount of circulating water equipment, the application of Treatment of Industrial Water technology is more and more extensive.Large scale industry circulation is divided into cold enzyme and cooling system.Cooling system is owing to being open type system, and cooling water is constantly cycle water use in systems in which, because water temperature is at about 40 DEG C, circulates for a long time and concentrates utilization, for the amount reproduction of microorganism creates condition, forms microorganism viscosity mud.A large amount of microorganism viscosity muds can make cooling water quality sharply worsen, corrosion inhibiting and descaling agent lost efficacy, and the hardware in cooling water system can be caused to corrode, cause a series of harm such as microbial fouling and corrosion, also can blocking pipe time serious, cause the reduction in recirculating cooling water system efficiency and life-span, directly huge harm is caused to industrial production.Therefore, while adding anti-incrustation corrosion inhibitor process, the most directly way is exactly the breeding adding microorganism in bactericide control system.
Conventional bactericide can be divided into oxidisability and the large class of non oxidizing bactericide two.Oxidizing bactericide is as liquid chlorine, clorox etc., although its sterilization algae removal speed is fast, efficiency of killing livestock is high, disposal cost is low, environmental pollution is little, microorganism not easily develops immunity to drugs to it, but also there is the impact being subject to Organic substance in water and reducing substances in it, action time is short, by the impact also drawback such as comparatively large, dispersion infiltration and peeling effect difference of pH value.And non oxidizing bactericide is not kill microorganism with oxidation, and consequently toxic action, in the privileged sites of microorganism, is not thus subject to the impact of reducing substances in water.Its effect of killing livestock has certain persistence, and have infiltration, stripping effect to sediments or glutinous mud, the impact by the reduction material such as hydrogen sulphide, ammonia, pH value is less.Bactericide commercially available is at present still based on the bactericide of one-component, and this series bactericidal agent has the shortcomings such as dosage is large, bactericide kind is single, fragmentation effect is poor, easily develop immunity to drugs.Patent of invention CN102726446A discloses a kind of circulation high efficiency composition bactericide, in this compound disinfectant, the quaternary ammonium salt of foam easy to foaming is replaced by the not easy to foaming and environment-friendly type quaternary alkylphosphonium salt of easily biological-degradable, auxiliary agent is replaced by the fast isothiazolinone of degradation speed and glutaraldehyde.Although glutaraldehyde is almost non-toxic, applicable pH range is wide, higher temperature resistant, it is the specific drug killing sulfate reducing bacteria, itself can biological degradation, but it very easily reacts with ammonia, aminated compounds and lose activity, and price is higher that its application is limited by very large.
Summary of the invention
The object of the invention is to: for the technical problem existed in background technology, a kind of efficient germicide being adapted to industrial circulating water cooling system is provided, this bactericide has the advantages that germicidal efficiency is high, pesticide resistance is low, applied widely, and production method is succinctly reasonable, farthest can reduce the production cost of enterprise.
Technical scheme of the present invention: a kind of efficient compound bactericide; described bactericide is made up of according to percentage by weight llowing group of materials: 2,2-bis-bromo-3-cyano group propionamide: 5-15%, poly ethylene oxide soya-bean oil acyl amine: 3-8%, ethylene glycol: 10-20%, 10% sulfuric acid: 3-8%, isothiazolinone: 5-15%, CuSO
43-8% and surplus are distilled water.
A kind of production method of efficient compound bactericide, described production method is made up of following step: wherein material forms according to above-mentioned percentage by weight, (1) by 2,2-bis-bromo-3-cyano group propionamide adds in reactor, and then in reactor, add poly ethylene oxide soya-bean oil acyl amine and ethylene glycol, fully stir 15-25 minute; (2) in aforesaid reaction vessel, add 10% sulfuric acid, fully stir 15 ~ 25 minutes; (3) in aforesaid reaction vessel, add isothiazolinone again, stir 5-10 minute; (4) in aforesaid reaction vessel, CuSO is added again
4, stir 5-10 minute; (5) finally in aforesaid reaction vessel, add distilled water again, stir 5-10 minute to obtain finished product.Described poly ethylene oxide soya-bean oil acyl amine is cosolvent; Described copper sulphate is stabilizing agent.
Wherein, 2.2-bis-bromo-3-cyano group propionamide is abbreviated as: DBNPA, as the biocide of broad-spectrum high efficacy, can penetrate rapidly the cell membrane of microorganism, and act on certain albumen group, the normal oxidation reduction of cell is stopped, thus causes cell death.Meanwhile, its branch can also the specific enzymes metabolite of optionally bromination or oxidizing microorganisms, finally causes microbial death.This product has good stripping performance, non-foam during use, and fluid product can arbitrarily than dissolving each other with water, low toxicity; Isothiazolinone: isothiazolinone is primarily of CMIT (CMI) and MIT (MI) composition, and isothiazolinone is key by disconnecting bacterium and algae protein matter and plays to kill livestock and act on; After isothiazolinone contacts with microorganism, can promptly irreversibly suppress it to grow, thus cause the death of microbial cell, therefore to common bacteria, fungi, algae etc., there is very strong suppression and killing action; CuSO
4: copper sulphate sterilization mechanism is that copper ion can make its sex change precipitate with microbial cells protein combination, thus bacterium is lost vigor; Ethylene glycol and poly ethylene oxide soya-bean oil acyl amine are solvent and cosolvent.Because the solvability of DBNPA is low, not soluble in water, add solid product and will cause bactericide skewness, the effect that sterilization onset is slow.Poly ethylene oxide soya-bean oil acyl amine is a kind of crystallinity, thermoplastic water-soluble polymer, can promote the dissolving of DBNPA.
Compound disinfectant of the present invention is 10 ~ 30mg/L at the working concentration of circulation.
Beneficial effect of the present invention: the compound disinfectant in the present invention forms primarily of DBNPA and isothiazolinone.Use because DBNPA is generally solid, its solvability is lower, and the use of solid product will cause its dispersion permeance property poor, and not easily bactericide compounded use with other, thus affect its efficiency of killing livestock.This patent carries out composite with isothiazolinone after adopting poly ethylene oxide soya-bean oil acyl amine and ethylene glycol they fully to be dissolved as solvent and auxiliary agent again, improves its efficiency of killing livestock.
Compound circulating water sterilizing agent in the present invention carries out composite forming by the organic sulfur series bactericidal agent in non-oxidative antimicrobial and organo bromine microbicide.Formed have concurrently DBNPA high-efficiency broad spectrum, easily degraded, noresidue residual hazard, environmentally safe, can the high efficiency composition bactericide of the advantages such as the low toxicity of sterilization algae removal, the advantage of killing the dirty and inhibition of sticky removing and isothiazolinone, non-foam, persistent, use cost be low simultaneously, this compound disinfectant to the heterotroph in cycle water and the Main microbial strains saprophytic bacteria in oil field reinjection water, iron bacteria, sulfate reducing bacteria all have excellent killing effect, speed of killing livestock is fast, power of killing livestock is strong, can control saprophytic bacteria sum in industrial circulating water and be less than 1*10
5, can make in oil field reinjection water to saprophytic bacteria, iron bacteria, sulfate reducing bacteria sterilizing rate reach 97%, 97%, more than 99% respectively.Simultaneously because its low toxicity, non-foam, persistent, advantage that use cost is low are more convenient for the application of its industrial production.
Embodiment
Embodiment 1: a kind of efficient compound bactericide; described bactericide is made up of according to percentage by weight llowing group of materials: 2,2-bis-bromo-3-cyano group propionamide: 5%, poly ethylene oxide soya-bean oil acyl amine: 3%, ethylene glycol: 10%, 10% sulfuric acid: 3%, isothiazolinone: 5%, CuSO
4: 3% and distilled water: 71%.
Production method is made up of following step: wherein material forms according to above-mentioned percentage by weight, (1) by 2,2-bis-bromo-3-cyano group propionamide adds in reactor, and then in reactor, add poly ethylene oxide soya-bean oil acyl amine and ethylene glycol, fully stirs 15-25 minute; (2) in aforesaid reaction vessel, add 10% sulfuric acid, fully stir 15-25 minute; (3) in aforesaid reaction vessel, add isothiazolinone again, stir 5-10 minute; (4) in aforesaid reaction vessel, CuSO is added the most again
4, stir 5-10 minute; (5) finally in aforesaid reaction vessel, add distilled water again, stir 5-10 minute to obtain finished product.
Embodiment 2, a kind of efficient compound bactericide; described bactericide is made up of according to percentage by weight llowing group of materials: 2,2-bis-bromo-3-cyano group propionamide: 15%, poly ethylene oxide soya-bean oil acyl amine: 8%, ethylene glycol: 20%, 10% sulfuric acid: 8%, isothiazolinone: 15%, CuSO
4: 8% and distilled water: 26%.
Production method is with embodiment 1.
Embodiment 3, a kind of efficient compound bactericide; described bactericide is made up of according to percentage by weight llowing group of materials: 2,2-bis-bromo-3-cyano group propionamide: 10%, poly ethylene oxide soya-bean oil acyl amine: 5%, ethylene glycol: 15%, 10% sulfuric acid: 5%, isothiazolinone: 10%, CuSO
4: 5% and distilled water: 50%.
Production method is with embodiment 1.
By experiment embodiment 1-3 is verified, test method:
Bactericide and commercially available isothiazolinone, 1227 (dodecyl benzyl dimethyl ammonium chlorides) prepared by the present invention is added in water sample, contact certain hour at 35 ± 2 DEG C after, according to the assay method in the analytical method of defined in " industrial circulating cooling water water quality analysis method rule " (HG/T3609-2000) and " oil field bactericide technical requirement ", measure remaining heterotroph number with plate count, measure saprophytic bacteria number, iron bacteria number, sulfate reducing bacteria number by MPN method.Meanwhile, make blank sample, contrast with former water sample bacteria containing amount and obtain sterilizing rate.
Result of the test:
Conclusion: as can be seen from above data, this compound disinfectant can meet " oil field bactericide technical requirement " (Q/SY49-2010), the requirement of " petrochemical industry water supply and drainage water quality index " (SH3099-2000) and " Code for design of industrial recirculating cooling water treatment " (GB50050-2007) middle microbiological indicator.Meanwhile, the sterilizing rate of this compound disinfectant all higher than commercially available isothiazolinone, the mono-product of DBNPA and 1227, excellent in sterilization effect.
Claims (2)
1. an efficient compound bactericide; it is characterized in that: described bactericide is made up of according to percentage by weight llowing group of materials: 2,2-bis-bromo-3-cyano group propionamide: 5-15%, poly ethylene oxide soya-bean oil acyl amine: 3-8%, ethylene glycol: 10-20%, 10% sulfuric acid: 3-8%, isothiazolinone: 5-15%, CuSO
4: 3-8% and surplus are distilled water.
2. the production method of an efficient compound bactericide, it is characterized in that: described production method is made up of following step: wherein material forms according to the percentage by weight described in claim 1, (1) by 2,2-bis-bromo-3-cyano group propionamide adds in reactor, and then in reactor, add poly ethylene oxide soya-bean oil acyl amine and ethylene glycol, fully stir 15-25 minute; (2) in aforesaid reaction vessel, add 10% sulfuric acid, fully stir 15-25 minute; (3) in aforesaid reaction vessel, add isothiazolinone again, stir 5-10 minute; (4) in aforesaid reaction vessel, CuSO is added again
4, stir 5-10 minute; (5) finally in aforesaid reaction vessel, add distilled water again, stir 5-10 minute to obtain bactericide finished product.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105191980A (en) * | 2015-09-14 | 2015-12-30 | 山东英联化学科技有限公司 | Compound sterilizing and alga killing agent for circulating cooling water and preparation method thereof |
| CN109169651A (en) * | 2018-08-17 | 2019-01-11 | 滨州市丰泰技术开发有限公司 | A kind of cationic surfactant and cupric sulfate compounded novel oilfield extraction water germicide |
| CN110839640A (en) * | 2019-11-28 | 2020-02-28 | 陕西省石油化工研究设计院 | Garbage sterilization deodorant and preparation method thereof |
| CN112023712A (en) * | 2020-09-16 | 2020-12-04 | 苏州东大汉森冶金实业有限公司 | Efficient multifunctional multipurpose reverse osmosis membrane scale inhibitor and preparation method and application thereof |
| CN112450217A (en) * | 2020-12-18 | 2021-03-09 | 湖南幻影三陆零科技有限公司 | Disinfectant and disinfectant composition containing same |
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| CN1650708A (en) * | 2004-02-04 | 2005-08-10 | 昆山鼎惠精细化工有限公司 | Disinfectant composition containing 2,2-dibromo-tricyano propanamide |
| CN101053329A (en) * | 2007-03-23 | 2007-10-17 | 新疆德蓝科技有限公司 | Bactericidal agent for treating sewage containing oil |
| CN101601409A (en) * | 2009-05-26 | 2009-12-16 | 兰州华星高科技开发有限公司 | Sterilization and alga-killing remover for circulating water |
| CN104068028A (en) * | 2014-06-25 | 2014-10-01 | 国家海洋局天津海水淡化与综合利用研究所 | Composite bacteria and algae inhibitor and application thereof |
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Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1575656A (en) * | 2003-07-24 | 2005-02-09 | 罗姆和哈斯公司 | Microbicidal composition |
| CN1650708A (en) * | 2004-02-04 | 2005-08-10 | 昆山鼎惠精细化工有限公司 | Disinfectant composition containing 2,2-dibromo-tricyano propanamide |
| CN101053329A (en) * | 2007-03-23 | 2007-10-17 | 新疆德蓝科技有限公司 | Bactericidal agent for treating sewage containing oil |
| CN101601409A (en) * | 2009-05-26 | 2009-12-16 | 兰州华星高科技开发有限公司 | Sterilization and alga-killing remover for circulating water |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105191980A (en) * | 2015-09-14 | 2015-12-30 | 山东英联化学科技有限公司 | Compound sterilizing and alga killing agent for circulating cooling water and preparation method thereof |
| CN109169651A (en) * | 2018-08-17 | 2019-01-11 | 滨州市丰泰技术开发有限公司 | A kind of cationic surfactant and cupric sulfate compounded novel oilfield extraction water germicide |
| CN110839640A (en) * | 2019-11-28 | 2020-02-28 | 陕西省石油化工研究设计院 | Garbage sterilization deodorant and preparation method thereof |
| CN112023712A (en) * | 2020-09-16 | 2020-12-04 | 苏州东大汉森冶金实业有限公司 | Efficient multifunctional multipurpose reverse osmosis membrane scale inhibitor and preparation method and application thereof |
| CN112450217A (en) * | 2020-12-18 | 2021-03-09 | 湖南幻影三陆零科技有限公司 | Disinfectant and disinfectant composition containing same |
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