CN104367916B - A kind of Chinese medicine preparation for treating nephrotic syndrome - Google Patents
A kind of Chinese medicine preparation for treating nephrotic syndrome Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/62—Nymphaeaceae (Water-lily family)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A—HUMAN NECESSITIES
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/79—Schisandraceae (Schisandra family)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9062—Alpinia, e.g. red ginger or galangal
Abstract
The invention discloses a kind of Chinese medicine preparation for being used to treat nephrotic syndrome, the bulk drug and its composition by weight of selection are respectively：20 30 grams of sealwort, 10 20 grams of Gorgon fruit, 10 20 grams of Ramulus Taxilli, 10 20 grams of dried orange peel, 10 20 grams of female grass, 10 20 grams of Poria cocos, 10 20 grams of Chinese yam, 10 20 grams of the fruit of Chinese magnoliavine, 10 20 grams of hairyvein agrimony, 8 15 grams of fructus alpiniae oxyphyllae halberd, 8 12 grams of raspberry, 8 12 grams of golden cypress, 8 12 grams of stone reed, 8 12 grams of mantis egg-case, 8 12 grams of dogwood fruit, 8 15 grams of Radix Codonopsis.All medicine compatibilities are superior, giving consideration to both the incidental and fundamental, tonification and purgation in combination and reinforcing earth to generate metal, tonifying speen and tonifying kidney is played altogether, invigorating qi for consolidating superficies, heat-clearing and damp-drying drug, the effect of promoting diuresis for stranguria, compared with traditional therapy have determined curative effect, it is cheap, have no side effect, the advantage that cure rate is high and uneasy to recur, clinic promotion and application.
Description
Technical field
It is specifically a kind of to treat the Chinese medicine preparation of nephrotic syndrome the invention belongs to the field of Chinese medicines.
Background technology
Nephrotic syndrome refers to as caused by Different types of etiopathogenises, is increased with glomerular basement membrane permeability and is dropped with glomerular filtration rate(GFR
One group of syndrome based on low Glomerular lesions.Clinical characters are mainly that High-grade Proteinuria (more than 3.5g/d, can there is lipid
Urine), hypoalbuminemia (seralbumin be less than 30g/L), hyperlipidemia and oedema.It is divided into i.e. according to different pathogeny and pathology
Nephrotic syndrome, congenital nephrotic syndrome, Secondary cases nephrotic syndrome.
Hormone and cytotoxic drug are used the current Modern medical therapy disease more, though there is certain curative effect, being difficult to thoroughly
Radical cure, and have suitable case insensitive to hormone, often there is hormone dependant or Steroid-Resistance in part infant, and prognosis is poor,
Furthermore, hormone and cytotoxic drug side effect are a lot, and recurrence rate is higher, not very good medicine.TCM Therapy is
The therapeutic features of China's nephrotic syndrome, therefore, we utilize according to tcm treatment according to syndrome differentiation, the principle treated both principal and secondary aspect of disease in recent years
A variety of Chinese herbal medicines mix fried Chinese medicine and obtain preferable curative effect to treat nephrotic syndrome, face improving nephrotic syndrome
Bed disease, improve life quality, delay renal function deteriorate in terms of have certain curative effect and advantage.
The content of the invention
Instant invention overcomes the technical deficiency existed at present in terms of nephrotic syndrome is treated, there is provided a kind of curative effect is true
Cut, it is cheap, have no side effect, the Chinese medicine preparation that cure rate is high and uneasy to recur.
The technical solution adopted in the present invention is：A kind of Chinese medicine preparation for treating nephrotic syndrome, it is characterised in that described
Chinese medicine preparation is made up of the Chinese herb of following parts by weight：
20-30 grams of sealwort, 10-20 grams of Gorgon fruit, 10-20 grams of Ramulus Taxilli, 10-20 grams of dried orange peel, 10-20 grams of female grass, Poria cocos 10-
20 grams, 10-20 grams of Chinese yam, 10-20 grams of the fruit of Chinese magnoliavine, 10-20 grams of hairyvein agrimony, 8-15 grams of fructus alpiniae oxyphyllae, 8-12 grams of raspberry, golden cypress 8-
12 grams, 8-12 grams of stone reed, 8-12 grams of mantis egg-case, 8-12 grams of dogwood fruit, 8-15 grams of Radix Codonopsis.
It is used as a kind of this prioritization scheme：
The Chinese medicine preparation is made up of the Chinese herb of following parts by weight：
20 grams of sealwort, 10 grams of Gorgon fruit, 10 grams of Ramulus Taxilli, 10 grams of dried orange peel, 10 grams of female grass, 10 grams of Poria cocos, 10 grams of Chinese yam, the five tastes
10 grams of son, 10 grams of hairyvein agrimony, 8 grams of fructus alpiniae oxyphyllae, 8 grams of raspberry, 8 grams of golden cypress, 8 grams of stone reed, 8 grams of mantis egg-case, 8 grams of dogwood fruit, party
8 grams of ginseng.
It is used as a kind of this prioritization scheme：
The Chinese medicine preparation is made up of the Chinese herb of following parts by weight：
25 grams of sealwort, 15 grams of Gorgon fruit, 15 grams of Ramulus Taxilli, 15 grams of dried orange peel, 15 grams of female grass, 15 grams of Poria cocos, 15 grams of Chinese yam, the five tastes
15 grams of son, 15 grams of hairyvein agrimony, 12 grams of fructus alpiniae oxyphyllae, 10 grams of raspberry, 10 grams of golden cypress, 10 grams of stone reed, 10 grams of mantis egg-case, dogwood fruit 10
Gram, 12 grams of Radix Codonopsis.
It is used as a kind of this prioritization scheme：
The Chinese medicine preparation is made up of the Chinese herb of following parts by weight：
30 grams of sealwort, 20 grams of Gorgon fruit, 20 grams of Ramulus Taxilli, 20 grams of dried orange peel, 20 grams of female grass, 20 grams of Poria cocos, 20 grams of Chinese yam, the five tastes
20 grams of son, 20 grams of hairyvein agrimony, 15 grams of fructus alpiniae oxyphyllae, 12 grams of raspberry, 12 grams of golden cypress, 12 grams of stone reed, 12 grams of mantis egg-case, dogwood fruit 12
Gram, 15 grams of Radix Codonopsis.
The instructions of taking of above-mentioned Chinese medicine preparation is：It is fried according to tradition after the raw material Chinese medicine of above-mentioned weight proportion is mixed
The method of Chinese medicine takes its concoction 200ml, daily 1 dose, divides 2 times orally.It is within 4 weeks 1 course for the treatment of.
The raw material Chinese medicine of above-mentioned Chinese medicine preparation：
Sealwort, it is sweet, it is mild-natured；Return lung, spleen, kidney channel.With nourshing kidney moistening lung, the effect of invigorating the spleen and benefiting qi.
Gorgon fruit, it is sweet, puckery, it is mild-natured；Returns spleen, kidney channel.With reinforcing the kidney and controlling noctural emission, the effect of tonifying spleen stopping leak.
Ramulus Taxilli, it is bitter, sweet, it is mild-natured；Return liver, kidney channel.With tonifying the liver and kidney, strengthening the muscles and bones, QI invigorating is antiabortive, remove rheumatism
The effect of.
Dried orange peel, pungent, hardship is warm-natured；Returns spleen, stomach, lung channel.With qi-regulating and in, it is eliminating dampness and eliminating phlegm, the effect of sharp water defaecation.
Female grass, pungent, hardship, cold nature；The thoughts of returning home, liver, bladder warp.With promoting blood circulation for regulating menstruation, the effect of inducing diuresis to remove edema.
Poria cocos, it is sweet, light, mild-natured；The thoughts of returning home, lung, the spleen channel.With eliminating dampness and diuresis, strengthening the spleen and stomach, the effect of antitoxic heart-soothing and sedative.
Chinese yam, it is sweet, it is mild-natured；Returns spleen, lung, kidney channel.With supplementing qi and nourishing yin, help spleen and lung, the effect of invigorating the kidney and stopping nocturnal emission.
The fruit of Chinese magnoliavine, it is sour, it is warm-natured；Return lung, kidney, the heart channel of Hang-Shaoyin.With nourshing kidney of astringing the lung, promote the production of body fluid arrest sweating, the effect of puckery smart antidiarrheal.
Hairyvein agrimony, it is bitter, puckery, it is mild-natured；Return lung, liver, the spleen channel.With astringing to arrest bleeding, the effect of stop dysentery.
Fructus alpiniae oxyphyllae, it is pungent, it is warm-natured；Returns spleen, kidney channel.With warming spleen and stopping diarrha, the effect of warming up kidney astringent sperm contracting urine.
Raspberry, sweet, acid is warm-natured；Return liver and kidney channel.With astringent sperm contracting urine, the effect of kidney-nourishing nourishing the liver.
Golden cypress, bitter is cold in nature；Return kidney, bladder, large intestine channel.With heat-clearing and damp-drying drug, purging intense heat and detonicating, the effect of clearing away deficiency-heat.
Stone reed, it is bitter, sweet, it is cool in nature；Return lung, bladder warp.With promoting diuresis for stranguria, the effect of clearing lung-heat expels the heat-evil.
Mantis egg-case, it is sweet, salty, it is mild-natured；Return liver and kidney channel.With astringent sperm contracting urine, the effect of tonifying the kidney and support yang.
Dogwood fruit, sour, slightly warm in nature；Return liver and kidney channel.With tonifying the liver and kidney, the effect of restraining astringent or styptic treatment for spontaneous sweating.
Radix Codonopsis, it is sweet, it is mild-natured；Returns spleen, lung channel.With tonifying middle-Jiao and Qi, promote the production of body fluid blood-nourishing the effect of.
The traditional Chinese medical science thinks that nephrotic syndrome is due to that spleen feritin is empty, exopathogen invasion, so that lung, spleen, the dirty function of kidney three
Imbalance, kidney deficiency then failure to store, vital essence is leaked, insufficiency of the spleen then biochemical weary source, so that cereal nutrient is deficient, wind-cold damp pathogen heap soil or fertilizer over and around the roots is tied in dirty
Internal organs, eventually because lung loses logical tune, spleen is not transferred, and kidney difficulty opens entire, aqueous dysbolism, water retention, and overflow skin, and cost is sick.
This disease belongs to the card of body ressitance weakened while pathogenic factors prevailing, using deficiency of spleen and stomach as this, using ailment said due to cold or exposure, cold-dampness, damp and hot, hemostasis as mark.In the present invention
In medicine preparation, sealwort, Gorgon fruit, Chinese yam, Ramulus Taxilli, raspberry, mantis egg-case, dogwood fruit, fructus alpiniae oxyphyllae, Radix Codonopsis mutual 5 can invigorating the spleen temperature
Kidney, invigorating qi for consolidating superficies, righting is without staying heresy, the medicine as effected a permanent cure, meanwhile, the lung belonging to metal, spleen pertaining to the earth is the source of biochemical qi and blood, autochthonal
Gold, invigorating the spleen energy tonifying lung, reinforcing earth to generate metal；Poria cocos, golden cypress, stone reed energy heat-clearing and damp-drying drug, purging intense heat and detonicating, eliminating dampness and diuresis, for the medicine taken stopgap measures,
Dried orange peel, female grass, the fruit of Chinese magnoliavine, hairyvein agrimony can qi-regulating and in, astringing to arrest bleeding is promoting production of body fluid and benefiting qi, tonifying Qi Li Shui, brings out the best in each other, Li Shui and
Do not hinder just.
All medicine compatibilities are superior, and giving consideration to both the incidental and fundamental, tonification and purgation in combination and reinforcing earth to generate metal, and tonifying speen and tonifying kidney is played altogether, and invigorating qi for consolidating superficies, heat-clearing is dry
It is wet, the effect of promoting diuresis for stranguria, circulated and be administered by channels and collaterals, the elite of medicine is delivered directly to kidney and the vital organs of the human body, transferred
Other organs of human body participate in toxin expelling, mitigate kidney burden, come the renal function for improving and recovering patient, so as to reach reparation kidney
Bead basilar memebrane, raising plasma albumin, reduction T-CHOL, elimination albuminuria, fundamentally recover the purpose of renal function.
The clinical efficacy and safety of medicine of the present invention are further investigated, we have selected 70 patients and carry out clinical examination
Test.Diagnostic criteria：1st, a large amount of Urine proteins (＞ 3.5g/24h)；2nd, Hypoproteinemia (haemocyanin ＜ 30g/L)；3rd, obvious water
It is swollen；4th, hyperlipidemia.In above-mentioned 4 conditions, first 2 are necessary condition.All patients are randomly divided into treatment group and control group,
Treatment group 35, man 18, female 17 is age 15-46 Sui, average 31.2 years old, wherein nephrotic syndrome 22, lupus
Property ephritis 8, HSPN 5, -1 year course of disease two weeks；Control group 35, man 16, female 19, age 19-50 Sui,
Average 31.7 years old, wherein nephrotic syndrome 19, lupus nephritis 9, HSPN 7, the course of disease 10 days -11
Month.Age of two groups of patients, sex, body weight, sick time, disease symptom isobase data are through statistical analysis, and difference is without system
Meter learns meaning (P ＞ 0.05), with comparativity.
Treatment method：
Chinese medicine preparation of the present invention is taken by treatment group, takes 20 grams of sealwort, 10 grams of Gorgon fruit, 10 grams of Ramulus Taxilli, 10 grams of dried orange peel, female grass
10 grams, 10 grams of Poria cocos, 10 grams of Chinese yam, 10 grams of the fruit of Chinese magnoliavine, 10 grams of hairyvein agrimony, 8 grams of fructus alpiniae oxyphyllae, 8 grams of raspberry, 8 grams of golden cypress, stone reed
8 grams, 8 grams of mantis egg-case, 8 grams of dogwood fruit, 8 grams of Radix Codonopsis (being added and subtracted with disease), take its medicine according to the method for traditional fried Chinese medicine after mixing
Juice 200ml, divides 2 times orally by daily 1 dose.It is within 4 weeks 1 course for the treatment of.The hormone of the control group standard course for the treatment of, metacortandracin, 1mg/
Kg/d, ACEI (illiteracy promise) 10mg/d, clothes of daily early morning.Judge curative effect after treating 8 weeks within two weeks.
Index for examination：The 2nd week, 4 weeks, 6 weeks routine that has urine examined, twenty-four-hour urine protein quantification, blood plasma before treatment and after treatment
Albumin, blood fat, serum creatinine, blood cell analysis etc..
Criterion of therapeutical effect:
It is effective：Urine proteins are turned out cloudy completely after treatment, edema disappears；
Effectively：Edema substantially mitigates or disappeared after treatment, Urine proteins are reduced to (+)-(++)；
It is invalid：Edema is without improvement after treatment, and Urine proteins are still >=(+++).
Efficacy result：
1. Clinical efficacy comparison：
After treatment, effective 14 for the treatment of group, effective 19, invalid 2, cure rate is 40.0%, and total effective rate reaches
94.3%；Effective 6 of control group, effective 18, invalid 11, cure rate is 17.1%, and total effective rate is 68.6%；Treatment group
Cure rate and efficient apparently higher than control group.(two groups of results compare P ＜ 0.01, and difference is statistically significant)
Table 1：Curative effect comparision result table after two groups of case treatments
| Group | Number of cases | Effective n (%) | Effective n (%) | Invalid n (%) | Total effective rate (%) |
| Treatment group | 35 | 14(40.0) | 19(54.3) | 2(5.7) | 94.3 |
| Control group | 35 | 6(17.1) | 18(51.4) | 11(31.4) | 68.6 |
2. twenty-four-hour urine protein quantification compares before and after treatment：
After treatment, treatment group's twenty-four-hour urine albumen urine volume is significantly reduced, and has conspicuousness, P ＜ with control group comparing difference
0.05.Detailed results are shown in Table 2.
Table 2：Twenty-four-hour urine protein quantification compares before and after two groups of treatments
| Packet | Before treatment | Treatment 2 weeks | Treatment 4 weeks | Treatment 8 weeks |
| Treatment group | 5.85±1.34 | 4.48±1.82 | 1.32±1.20 | 0.10±0.08 |
| Control group | 5.79±1.24 | 4.36±1.74 | 1.43±1.55 | 0.39±0.11 |
3. treatment Plasma Before And After albumen compares：
After treatment, treatment group's plasma protein is obviously improved, and has conspicuousness, P ＜ 0.05 with control group comparing difference.Tie in detail
Fruit is shown in Table 3.
Table 3：Two groups for the treatment of Plasma Before And After albumen compare
| Packet | Before treatment | Treatment 2 weeks | Treatment 4 weeks | Treatment 8 weeks |
| Treatment group | 19.9±3.15 | 26.33±5.55 | 34.51±4.23 | 39.41±3.21 |
| Control group | 20.39±4.18 | 25.01±7.33 | 30.44±5.25 | 35.33±1.26 |
4. adverse reaction is compared：
Count two groups of patients in the treatment bad hair should, in control group 2 patients occur it is dizzy, 6 patients occur nausea,
Vomiting, poor appetite, are alleviated with after Domperidone anti symptom treatment.Treatment group has no obvious adverse reaction.
As a result show, Chinese medicine preparation of the present invention is first based on training of reinforcing the kidney, Yin Yang balancing, bidirectional modulation immunity of organism, so that
Reparation activation kidney regenerative cell is reached, albuminuria, blood urine is eliminated, reduction serum creatinine, urea nitrogen thoroughly cure nephrotic syndrome
Purpose.Compared with traditional therapy have determined curative effect, it is cheap, have no side effect, cure rate it is high and uneasy to recur
Advantage, clinic promotion and application.
Embodiment
Embodiment 1：One kind treats nephrotic syndrome Chinese medicine preparation, choose 20 grams of sealwort, 10 grams of Gorgon fruit, 10 grams of Ramulus Taxilli,
10 grams of dried orange peel, 10 grams of female grass, 10 grams of Poria cocos, 10 grams of Chinese yam, 10 grams of the fruit of Chinese magnoliavine, 10 grams of hairyvein agrimony, 8 grams of fructus alpiniae oxyphyllae, raspberry 8
Gram, 8 grams of golden cypress, 8 grams of stone reed, 8 grams of mantis egg-case, 8 grams of dogwood fruit, 8 grams of Radix Codonopsis.
Embodiment 2：One kind treats nephrotic syndrome Chinese medicine preparation, choose 25 grams of sealwort, 15 grams of Gorgon fruit, 15 grams of Ramulus Taxilli,
15 grams of dried orange peel, 15 grams of female grass, 15 grams of Poria cocos, 15 grams of Chinese yam, 15 grams of the fruit of Chinese magnoliavine, 15 grams of hairyvein agrimony, 12 grams of fructus alpiniae oxyphyllae, raspberry 10
Gram, 10 grams of golden cypress, 10 grams of stone reed, 10 grams of mantis egg-case, 10 grams of dogwood fruit, 12 grams of Radix Codonopsis.
Embodiment 3：One kind treats nephrotic syndrome Chinese medicine preparation, choose 30 grams of sealwort, 20 grams of Gorgon fruit, 20 grams of Ramulus Taxilli,
20 grams of dried orange peel, -20 grams of female grass, -20 grams of Poria cocos, 20 grams of Chinese yam, 20 grams of the fruit of Chinese magnoliavine, 20 grams of hairyvein agrimony, 15 grams of fructus alpiniae oxyphyllae, raspberry
12 grams, 12 grams of golden cypress, 12 grams of stone reed, 12 grams of mantis egg-case, 12 grams of dogwood fruit, 15 grams of Radix Codonopsis.
The Chinese medicine preparation curative effect of the present invention is further verified below by specific case：
Case 1
Week certain, man, 24 years old.There is height edema after being caught a cold before 2 years in patient, routine urianlysis albumen (++++), it is white thin
Born of the same parents (++++), nephrotic syndrome is diagnosed as in local hospital, symptomatic treatment is not felt any better for 1 year, and constitution worse and worse, is walked and all eaten very much
Power, household is very desperate, thinks child dying.After hear Chinese medicine preparation treatment effect of the present invention preferably, cured many kidneys
Patient, just has the attitude tried in arms, and edema disappears after taking medicine 4 weeks, and albumen remains 3 "+", and physical symptom is obviously improved.After
Continuous to take after 2 courses for the treatment of, patient sign recovers normal, and clinical indices chemical examination recovers normal value, patient's recovery from illness.Follow-up 1 year
No relapse.
Case 2
Song, man, 35 years old.3 years causes of patient are that the infection of the upper respiratory tract causes morbidity, are initially malaise, the soreness of waist, face
Face and edema of pair of lower extremities, oedema was extremely serious from head to foot later, eyes macular area also oedema during most serious, Urine proteins " ++++", doctor
Institute, which checks, is diagnosed as nephrotic syndrome, and with hormones and treated with cyclophosphamide pulse, albumen is dropped to " ++ ", but side effect is big, and
Curative effect is not that very significantly protein level maintains " ++ " all the time.After being introduced, start to take Chinese medicine preparation treatment of the present invention, use
Medicine is rechecked albumen for 3 weeks and begun to decline as "+", stable disease.Patient's great rejoicing, holds on after 2 courses for the treatment of of medication, whole body sign is extensive
It is multiple normal, recheck Urine proteins index and recover normal value, patient's recovery from illness.1 year no relapse of follow-up.
Case 3
Ten thousand certain, female, 45 years old.Patient is not added in meaning in being caught a cold before 1 year, engenders that eyelid and double lower limb moderate are floating afterwards
It is swollen, hospital's routine urianlysis：Urine proteins " ++++", granular cast " ++ ", pyocyte is a little, and red blood cell is a little.Hospital, which is given, infuses,
Diuretics for oral administration, and use after prednisone treatment, symptom mitigation, but leave hospital less than first quarter moon, edema is aggravated, and ascites is serious.Listen
It is evident in efficacy that friend introduces Chinese medicine preparation treatment nephrotic syndrome of the present invention, then starts to take 1 course for the treatment of and is treated, medication
Finish, patient's readme clinical symptoms are obviously improved, recheck Urine proteins " ++ ", continue 2 courses for the treatment of of medication and carry out after after treatment, face
Bed body levies recovery normally, rechecks indices and reaches normal value, Rehabilitation.No recurrence was observed during the follow-up period of 6 months.
Claims (4)
1. one kind treats nephrotic syndrome Chinese medicine preparation, it is characterised in that the Chinese medicine preparation is former by the Chinese medicine of following parts by weight
Material is constituted：
20-30 grams of sealwort, 10-20 grams of Gorgon fruit, 10-20 grams of Ramulus Taxilli, 10-20 grams of dried orange peel, 10-20 grams of female grass, Poria cocos 10-20
Gram, 10-20 grams of Chinese yam, 10-20 grams of the fruit of Chinese magnoliavine, 10-20 grams of hairyvein agrimony, 8-15 grams of fructus alpiniae oxyphyllae, 8-12 grams of raspberry, golden cypress 8-12
Gram, 8-12 grams of stone reed, 8-12 grams of mantis egg-case, 8-12 grams of dogwood fruit, 8-15 grams of Radix Codonopsis.
2. Chinese medicine preparation according to claim 1, it is characterised in that the Chinese medicine preparation is former by the Chinese medicine of following parts by weight
Material is constituted：
20 grams of sealwort, 10 grams of Gorgon fruit, 10 grams of Ramulus Taxilli, 10 grams of dried orange peel, 10 grams of female grass, 10 grams of Poria cocos, 10 grams of Chinese yam, the fruit of Chinese magnoliavine 10
Gram, 10 grams of hairyvein agrimony, 8 grams of fructus alpiniae oxyphyllae, 8 grams of raspberry, 8 grams of golden cypress, 8 grams of stone reed, 8 grams of mantis egg-case, 8 grams of dogwood fruit, Radix Codonopsis 8
Gram.
3. Chinese medicine preparation according to claim 1, it is characterised in that the Chinese medicine preparation is former by the Chinese medicine of following parts by weight
Material is constituted：
25 grams of sealwort, 15 grams of Gorgon fruit, 15 grams of Ramulus Taxilli, 15 grams of dried orange peel, 15 grams of female grass, 15 grams of Poria cocos, 15 grams of Chinese yam, the fruit of Chinese magnoliavine 15
Gram, 15 grams of hairyvein agrimony, 12 grams of fructus alpiniae oxyphyllae, 10 grams of raspberry, 10 grams of golden cypress, 10 grams of stone reed, 10 grams of mantis egg-case, 10 grams of dogwood fruit,
12 grams of Radix Codonopsis.
4. Chinese medicine preparation according to claim 1, it is characterised in that the Chinese medicine preparation is former by the Chinese medicine of following parts by weight
Material is constituted：
30 grams of sealwort, 20 grams of Gorgon fruit, 20 grams of Ramulus Taxilli, 20 grams of dried orange peel, 20 grams of female grass, 20 grams of Poria cocos, 20 grams of Chinese yam, the fruit of Chinese magnoliavine 20
Gram, 20 grams of hairyvein agrimony, 15 grams of fructus alpiniae oxyphyllae, 12 grams of raspberry, 12 grams of golden cypress, 12 grams of stone reed, 12 grams of mantis egg-case, 12 grams of dogwood fruit,
15 grams of Radix Codonopsis.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101069722A (en) * | 2006-05-09 | 2007-11-14 | 广州康臣药业有限公司 | Chinese medicine composition for treating kidney disease syndrome and preparing method |
| CN101259232A (en) * | 2008-04-25 | 2008-09-10 | 北京中泰天和科技有限公司 | Chinese medicinal composition for treating nephrotic syndrome and preparation thereof |
| CN101757540A (en) * | 2009-10-31 | 2010-06-30 | 泰一和浦（北京）中医药研究院有限公司 | Traditional Chinese medicine composition for treating nephrotic syndrome and preparation method thereof |
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| CN101069722A (en) * | 2006-05-09 | 2007-11-14 | 广州康臣药业有限公司 | Chinese medicine composition for treating kidney disease syndrome and preparing method |
| CN101259232A (en) * | 2008-04-25 | 2008-09-10 | 北京中泰天和科技有限公司 | Chinese medicinal composition for treating nephrotic syndrome and preparation thereof |
| CN101757540A (en) * | 2009-10-31 | 2010-06-30 | 泰一和浦（北京）中医药研究院有限公司 | Traditional Chinese medicine composition for treating nephrotic syndrome and preparation method thereof |
Non-Patent Citations (2)
| Title |
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| 中药复方联合雷公藤甲素对原发性肾病综合征患者尿蛋白与脂蛋白的影响;万毅刚等;《中医杂志》;20030630;第44卷(第06期);第427-429页 * |
| 中西医结合治疗原发性肾病综合征;冯小云等;《新疆中医药》;20000625;第18卷(第2期);第40-42页 * |
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