CN104367301B - Vascular endothelial function noninvasive detector and detection method thereof - Google Patents
Vascular endothelial function noninvasive detector and detection method thereof Download PDFInfo
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- CN104367301B CN104367301B CN201410680126.8A CN201410680126A CN104367301B CN 104367301 B CN104367301 B CN 104367301B CN 201410680126 A CN201410680126 A CN 201410680126A CN 104367301 B CN104367301 B CN 104367301B
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0033—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
- A61B5/004—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
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- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
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- A61B5/48—Other medical applications
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Abstract
The invention belongs to the technical field of medical products and particularly relates to a vascular endothelial function noninvasive detector and a detection method thereof. The noninvasive detector comprises a movable control operation trolley, a computer with a double-screen displayer, a cuff type pressurization device and a thermal image collection positioning background device, wherein the brachial artery position of the observation side of an upper limb of a detected human body is sleeved with the cuff type pressurization device, and the cuff type pressurization device applies pressure. The vascular endothelial function noninvasive detector further comprises a thermal infrared imager installed on the movable control operation trolley. The thermal infrared imager is used for collecting thermal energy information given out by the detected part of the human body, the thermal energy information is converted into digital signals through a hardware circuit, and the digital signals are transmitted to the computer. The detector is more flexible and convenient to use, thermal state distribution changes caused by blood flow changes and amplitude variation of temperature increasing and decreasing of the whole upper limb can be collected and observed simultaneously, information is richer, and the vascular endothelial function is accurately detected in time.
Description
Technical field
The invention belongs to curable product technical field, particularly to a kind of vascular endothelial function non-invasive detector and its detection
Method.
Background technology
In prior art, cardiovascular disease develops, and how to be started with cardiovascular endothelial function disturbance.Thought in the past,
Blood vessel endothelium is only a kind of mechanical barrier, and the flowing for blood provides a smooth physical surface.Recent study result
Confirm, vascular endothelial cell is a very active endocrine organ, has multiple important biological activitys, can experience physiology
Stimulate, make regulation reaction simultaneously, to maintain the balance of Ink vessel transfusing environment, maintain as important " adjusting tissue " in vivo
The stable state of cardiovascular system, and endothelial function disturbance is almost relevant with known all cardiovascular disease.
Crowd to Long Term Contact vascular endothelial injury risk factor, carries out the early detection of vascular endothelial function, finds
Abnormal, take some countermeasures in early days, prevention and retarding cardiovascular diseases are developed, there is particularly important meaning.
At present relatively frequently with blood vessel inner skin cell function Non-invasive detection instrument have following two：
Using pressure sensing technology (peripheral artery tonometry, PAT；Endo PAT as Israel)；
(2) ultrasonic technique (flow mediated dilation, FMD, the such as FMD of Germany).
Both technology clinically, are all the arteries to detected person side limbs (upper limb) with external force (air pressure)
Carry out the bloodstream blocking of certain time, another limbs make reference, then pressure relief blocks suddenly, then comparative observation detected person
The hemodynamic change of left and right sides limb artery；Using pressure sensing technology instrument generally with pressure cuff to detected person side
Brachial artery impose the pressure of 200～300mmhg, pressure relief suddenly again after 5 minutes, to detected person's bilateral before and after pressure
The change of its fluctuating signal waveform observed by upper limb tip pressure transducer fingerstall；And the instrument using ultrasonic technique is also to adopt
Above-mentioned means press to the far-end of detected person side brachial artery, in unexpected pressure relief after 5 minutes；Use before and after pressure simultaneously
Ultrasonic probe observes the change of artery structure at brachial artery.
Above two technology be clinically considered to meaningful, but be individually present following in clinical practice
Some limitations：
(1) pressure sensing technology (PAT) there are easily is affected by ambient environmental factors and autonomic nerve, and has detection
The single problem of information, typically can only gather the local message of regulation, if there is recessive vascular lesion in collected finger, this
The result of sample collection is inaccurate, it is understood that there may be can cause the risk of mistaken diagnosis；
(2) ultrasonic technique (FMD) needs well-trained operator, and blood pressure cuff position, tangent plane are chosen and probe pressing
Dynamics all can produce impact to result, and therefore, the accuracy of result is difficult to control.
Content of the invention
The purpose of the present invention is to overcome the deficiencies in the prior art, provides a kind of vascular endothelial function non-invasive detector, this inspection
Survey instrument use upper more flexible and convenient, can gather simultaneously observe the hot changes in distribution that whole upper limb causes because of hemodynamic change and
The amplitude of variation of gradient of temperature, information is abundanter, and vascular endothelial function is made with detection promptly and accurately.
In order to overcome above-mentioned technical purpose, the present invention is to realize by technical scheme below：
Vascular endothelial function non-invasive detector of the present invention, shows including portable control operation chassis, with double screen
Show the computer of device, be enclosed within detected person's upper limb observation side brachial artery and apply stressed cuff type pressue device, Yi Jire
As collection positioning Background apparatus；Also include the thermal infrared imager being installed on portable control operation chassis：For gathering human body
The heat energy information that tested position sends, heat energy information is converted into digital signal by hardware circuit and sends computer to.
As the improvement further of above-mentioned technology, the table top of described movable type control operation chassis is provided with feature operation area
With information gathering area, described thermal infrared imager corresponds to the top in information gathering area, and described Biscreen display is placed in feature operation
Area.
As the further improvement of above-mentioned technology, the table top of described movable type control operation chassis is adopted corresponding to information
Collection area edge is provided with an installation column, and described installation column is provided with the arm for being hung with thermal infrared imager.
In the present invention, described cuff type pressue device includes being sequentially connected air bag cuff, loading controls, piezometer
And the appendix for connecting.
In the present invention, described Biscreen display is included towards first display of detected person with for making to operator
Second display.
In the present invention, described thermal imagery collection positioning Background apparatus include metal background board, are placed in metal background plate surface
Nonmetallic aperture plate, refrigerator, and the temperature detection circuit electrically connecting with refrigerator.This thermal imagery is gathered positioning Background apparatus
It is applied on detector, effectively increase the accurate objective of information data and the sharpness of definition of image.
Invention additionally discloses a kind of detection method of vascular endothelial function non-invasive detector, it comprises the concrete steps that：
(1) start, make detected person that both upper extremities forearm to be placed in the region of regulation under thermal infrared imager；
(2) then, the heatmap information of detected person's both upper extremities forearm is gathered by thermal infrared imager；
(3) and then, block brachial artery or the femoral artery blood flow t1 for a period of time of side upper limb with air bag cuff air pressure；
(4) then, discharge cuff gas；
(5) detected person's bilateral before and after operator is pressed by the second display Continuous Observation being connected with thermal infrared imager
The amplitude situation of hot distribution change and temperature change, detected person's simultaneous observation in the thermal map of upper forearm；
(6) not apply the thermal map of air pressure side as hot distribution in the thermal map of control sides comparative analysiss pressure side upper forearm
Change and the amplitude situation of temperature change；
(7) last, it is analyzed, preserves or passes through printer by computer and print and draw analysis report.
As the improvement further of above-mentioned technology, the Xining t1 in described step (3) is 5 minutes.
Compared with prior art, the invention has the beneficial effects as follows：
(1), compared to the pressure sensing technology of prior art and ultrasonic technique, it can be more flexible on using for the present invention
Convenient, information is abundanter, can gather simultaneously observe hot changes in distribution and the temperature that whole upper limb causes because of hemodynamic change
The amplitude of variation of lifting, is provided that accurate testing result, and the timely discovery for blood vessel endothelium disease and treatment offer are strong
Foundation；
(2) non-invasive detection methods of the present invention are Non-invasive detection method, and the same time is affected little, also not by peripheral environment
The accuracy that result can be affected because the maneuver of operation is unskilled.
Brief description
With specific embodiment, the present invention is described in detail below in conjunction with the accompanying drawings：
Fig. 1 is vascular endothelial function non-invasive detector structural representation of the present invention；
Fig. 2 is heretofore described thermal imagery collection positioning Background apparatus structural representation.
Specific embodiment
As shown in figure 1, vascular endothelial function non-invasive detector of the present invention, including portable control operation chassis 1,
Computer 2 with Biscreen display, it is enclosed within detected person's upper limb observation side brachial artery and applies stressed cuff type pressurization
Device 3, and thermal imagery collection positioning Background apparatus 4；Also include the thermal infrared imager being installed on portable control operation chassis
5：For gathering the heat energy information that the tested position of human body sends, heat energy information is converted into digital signal by hardware circuit and transmits
To computer 2, software is installed in described main frame, the infrared information collection of non-invasive detector, information preserve and information
Analyzing and diagnosing function is all to be completed by this software.
The table top of described movable type control operation chassis 1 is provided with feature operation area I and information gathering area II, described infrared
Thermal imaging system 5 corresponds to the top in information gathering area, and described Biscreen display is placed in feature operation area I.
It is provided with an installation column 6 corresponding to information gathering area II edge on the table top of described movable type control operation chassis 1,
Described installation column 6 is provided with the arm 7 for being hung with thermal infrared imager 5.
Air bag cuff that described cuff type pressue device 4 includes being sequentially connected, loading controls, piezometer and for even
The appendix connecing.
Described Biscreen display include towards detected person 10 the first display 8 and for operator use second
Display 9, the first display 8 allows detected person see the thermal map image of collection, so that detected person is synchronously gazed at and joins
Close and check, reduce influence factor；Second display 9 is to observe to operator using.
As shown in Fig. 2 described thermal imagery collection positioning Background apparatus 4 include having the metal background board 41 of internal cavities, put
In the nonmetallic aperture plate 42 of metal background plate surface, refrigerator and the temperature detection circuit electrically connecting with refrigerator, described system
Cooler and temperature detection circuit are placed in the internal cavities of metal background board 41.
Described thermal imagery collection positioning Background apparatus 4 have following effect：
(1) described thermal imagery collection positioning Background apparatus 4 play the positioning action to measured target, and detected person 10 is by arm
It is seated on the nonmetallic aperture plate 42 on metal background board 41 surface it is possible to carry out detection and localization exactly；
(2) low temperature background of information gathering noise reduction is provided, because metal background board 41 is built-in with refrigerator, the holding of refrigerator
Colder temperature is held in continuation of insurance, to provide the low temperature background of tool decrease of noise functions, more can accurately gather heatmap information；
(3) real time correction is carried out to the temperature of thermal imagery；
(4) physical size of nonmetallic aperture plate 42 provides the reference of conversion for the area calculating Temperature Distribution.Therefore, will be upper
State thermal imagery collection positioning Background apparatus 4 to be applied on detector, it can increase accurate objective and the figure of information data effectively
The sharpness of definition of picture.
Invention additionally discloses a kind of detection method of vascular endothelial function non-invasive detector, it comprises the concrete steps that：
(1) start, both upper extremities forearm is placed in the region of thermal infrared imager 5 lower section regulation detected person 10, that is, believe
Breath acquisition zone II；
(2) then, the heatmap information of detected person 10 both upper extremities forearm is gathered by thermal infrared imager 5；
(3) and then, block brachial artery or the femoral artery blood of side upper limb with the air bag cuff air pressure of cuff type pressue device 3
Stream 5 minutes；
(4) then, the gas in the air bag cuff of release cuff type pressue device 3；
(5) detected person before and after operator is pressed by second display 10 Continuous Observation being connected with thermal infrared imager 5
The amplitude situation of hot distribution change and temperature change, detected person's simultaneous observation in the thermal map of both upper extremities forearm；
(6) not apply the thermal map of air pressure side as hot distribution in the thermal map of control sides comparative analysiss pressure side upper forearm
Change and the amplitude situation of temperature change；
(7) last, storage is analyzed by computer 2 or and is printed by printer and draw analysis report.
The invention is not limited in above-mentioned embodiment, every various changes to the present invention or modification without departing from the present invention
Spirit and scope, if these are changed and within the scope of modification belongs to claim and the equivalent technologies of the present invention, then this
Bright also implying that comprises these changes and modification.
Claims (6)
1. a kind of vascular endothelial function non-invasive detector it is characterised in that：Show including portable control operation chassis, with double screen
Show the computer of device, be enclosed within detected person's upper limb observation side brachial artery and apply stressed cuff type pressue device, Yi Jire
As collection positioning Background apparatus；
Also include the thermal infrared imager being installed on portable control operation chassis：For gathering the heat that the tested position of human body sends
Energy information, heat energy information is converted into digital signal by hardware circuit and sends computer to；Described thermal imagery collection positioning background
Device includes metal background board, the nonmetallic aperture plate being placed in metal background plate surface, refrigerator, and electrically connect with refrigerator
Temperature detection circuit.
2. vascular endothelial function non-invasive detector according to claim 1 it is characterised in that：Described movable type control operation
The table top of chassis is provided with feature operation area and information gathering area, and described thermal infrared imager corresponds to the top in information gathering area,
Described Biscreen display is placed in feature operation area.
3. vascular endothelial function non-invasive detector according to claim 2 it is characterised in that：Described movable type control operation
It is provided with an installation column corresponding to information gathering area edge, described installation column is provided with red for being hung with the table top of chassis
The arm of outer thermal imaging system.
4. vascular endothelial function non-invasive detector according to claim 1 it is characterised in that：Described cuff type pressue device
Including the air bag cuff being sequentially connected, loading controls, piezometer and the appendix for connecting.
5. vascular endothelial function non-invasive detector according to claim 1 it is characterised in that：Described Biscreen display includes
The first display and the second display for using to operator towards detected person.
6. the detection method of vascular endothelial function non-invasive detector according to claim 1, it comprises the concrete steps that：
(1) start, make detected person that both upper extremities forearm to be placed in the region of regulation under thermal infrared imager；
(2) then, the heatmap information of detected person's both upper extremities forearm is gathered by thermal infrared imager；
(3) and then, block brachial artery or the femoral artery blood flow t1 for a period of time of side upper limb, Xining with air bag cuff air pressure
T1 is 3～5 minutes；
(4) then, discharge cuff gas；
(5) detected person's both upper extremities before and after operator is pressed by the second display Continuous Observation being connected with thermal infrared imager
The amplitude situation of hot distribution change and temperature change, detected person's simultaneous observation in the thermal map of forearm；
(6) changed using the thermal map not applying air pressure side as hot distribution in the thermal map of control sides comparative analysiss pressure side upper forearm
And the amplitude situation of temperature change；
(7) last, it is analyzed, preserves or passes through printer by computer and print and draw analysis report.
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| CN104757945A (en) * | 2015-04-27 | 2015-07-08 | 成都维远艾珏信息技术有限公司 | Wireless medical temperature measurement system |
| CN104939989B (en) * | 2015-06-30 | 2017-12-22 | 黄劲涛 | A kind of multifunctional physiotherapeutic |
| CN105852910A (en) * | 2016-04-18 | 2016-08-17 | 何宗彦 | Equipment and method for detecting vascular endothelial functions by Doppler ultrasonography |
| CN107461581A (en) * | 2017-09-21 | 2017-12-12 | 武汉资联虹康科技股份有限公司 | A kind of dual-screen display device |
| CN113616165A (en) * | 2021-08-07 | 2021-11-09 | 郑州海威光电科技有限公司 | Infrared thermal image mobile inspection station |
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| CN204306798U (en) * | 2014-11-24 | 2015-05-06 | 北京爱尔慈红外医学科技有限公司 | A kind of vascular endothelial function non-invasive detector |
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| CN201558106U (en) * | 2009-12-02 | 2010-08-25 | 广州呼吸疾病研究所 | Universal telescopic integrated infrared thermal imaging detector |
| JP5960981B2 (en) * | 2011-12-19 | 2016-08-02 | 国立大学法人広島大学 | Endothelial function evaluation device |
| CN103385734B (en) * | 2012-11-15 | 2016-08-24 | 广州呼研所红外科技有限公司 | Infrared thermal imagery is utilized to guide ultrasonic duplication check comprehensive diagnostic instrument and the detection method of this diagnostic apparatus |
| CN103536281A (en) * | 2013-10-30 | 2014-01-29 | 广东省医疗器械研究所 | Vascular endothelial function detecting device based on fingertip temperature change |
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