CN104353167B - A kind of PEP Ventilation mask with external diaphragm pacing function - Google Patents

A kind of PEP Ventilation mask with external diaphragm pacing function Download PDF

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Publication number
CN104353167B
CN104353167B CN201410716981.XA CN201410716981A CN104353167B CN 104353167 B CN104353167 B CN 104353167B CN 201410716981 A CN201410716981 A CN 201410716981A CN 104353167 B CN104353167 B CN 104353167B
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mask
sensor
pep
module
diaphragm pacing
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CN104353167A (en
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马德东
鹿洪秀
曲仪庆
刘庆
邢影
田辉
李文培
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Qilu Hospital of Shandong University
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Qilu Hospital of Shandong University
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Abstract

The invention discloses a kind of PEP Ventilation mask with external diaphragm pacing function, including PEP mask and diaphragm pacing device, PEP mask is provided with several check valves;Check valve is connected with mask, and during by mask air-breathing, check valve is opened, and during expiration, closed check valve starts until air-breathing next time, sets up epithelium healing malleation when exhaling;Diaphragm pacing device includes sensing unit, diaphragm pacemaker and electrode, sensing unit includes pneumatic sensor, sound transducer, thorax abdomen motion sensor and oxygen saturation sensor, sensor unit connects diaphragm pacemaker by the interface of respective sensor, corresponding electric pulse is sent, the electric impulse signal of generation is input to electrode the phrenic nervess traveling body surface of monitored people;The present invention has good effect to central and obstructive sleep apnea, and the method for existing continuous positive pressure venti lation, surgical operation and lower jaw correction does not have direct therapeutical effect to centric sleep apnea.

Description

A kind of PEP Ventilation mask with external diaphragm pacing function
Technical field
The present invention relates to a kind of PEP Ventilation mask with external diaphragm pacing function.
Background technology
Obstruction sleep apnea-hypopnea syndrome (OSAHS) is a kind of very common disease, is characterized in sleeping During dormancy, epithelium healing partly or entirely subsides, and causes related disordered breathing of sleeping.Serious OSAHS can cause serious danger Evil:Cardia cevent, drowsiness, the carbohydrate metabolism disturbance on daytime, or even asphyxia.The OSAHS prevalences of external report are 2%~ 4%, and all increase with the age.Domestic data shows:Hongkong (30~60 years old) prevalence male is 4.1%, Nv Xingwei 2.1%.Shanghai (> 30 years old) prevalence is 3.6%, estimates OSAHS patient at least 2000 of China's age more than 30 years old accordingly Ten thousand.
Clear and definite OSAHS is the independent hazard factor for causing hypertension outside the factors such as obesity, heredity, smoking at present.OSAHS Dependency relation is not only existed between hypertension, and is cause effect relation.During epidemiological study result shows hyperpietic OSAHS prevalences about 30%~50%, in OSAHS patient, Prevalence of Hypertension is 50%~80%, high blood in population Pressure prevalence is usually 10%~20%.Refractory hypertension, simple medication effect mostly are by the hypertension that OSAHS causes Difference.Satisfied effect can be received if taking correct therapeutic strategy (Drug therapy+CPAP etc.).Common hyperpietic is (i.e. non- OSAHS causers) belong to Wood-scoop type more, and by, in the hyperpietic that causes of moderate or severe OSAHS the non-Wood-scoop type of 69.4% category.First, blood Pressure rising mostly occurred in night and early morning, is difficult to find its dysarteriotony if do not carried out 24 hours monitoring of blood pressure, thus has hidden The property hidden, is difficult early discovery.Second, easily there is left ventricular hypertrophy in Non-dipper hypertension, and Diastole Function goes down.Its disease 4.5 times for dipper hypertension of dead rate.
One investigation of Japan finds that the Relative hazard that OSAHS patient suffers from ischemic heart desease (IHD) is general population's 1.2~6.9 times, AHI >=10 time of 35%~40%IHD patients/hour, 23.8% OSHAS patient suffers from IHD simultaneously.Weight In degree OSAHS patient, 50% suffers from coronary heart disease, and nearly 30% OSAHS patient occurs myocardial ischemia during nighttime sleep, especially Which is in REM sleep phase.The results of study such as Peker P show that the patient with OSAHS dies from myocardium stalk during follow-up in 5 years (without OSAHS, 9.3%) probability (37.5%) of dead and apoplexy is significantly higher than matched group.There is mistake aroused in interest in 80%OSAHS patient Slow, ventricular premature contraction incidence rate is 57%~74%.More than 10% patient can occur II Aminophyline.Work as SaO2<60% When may occur in which frequently premature beat.56.2% generation arrhythmia in 146 OSAHS patients, including morning are reported according to Concord Hospital Fight, tachycardia, atrioventricular block etc..CHF patient 40%~60% merges sleep disordered breathing.Predominantly central sleep Asphyxia.
OSAHS is in close relations with diabetes, especially relevant with insulin resistant, after the treatment OSAHS that adopts an effective measure, Diabeticss Insulin Curative is obviously improved, it is thus regarded that OSAHS is probably the main cause for causing insulin resistant. OSAHS is also asymptomatic albuminuria high risk factor, particularly with hypertension and the crowd of diabetes.
Primary treatment measure at present includes surgical operation, appliance, noninvasive positive pressure ventilation.Surgical operation is the most frequently used Art formula:Uvulopalatopharyngoplasty (Uvulopalato-pharyngoplasty, UPPP) and its improvement operation are usually used in upper gas Road pars oralis pharyngises obstruction (include pharyngeal mucosa tissue is plump, pharyngeal cavity is narrow and small, uvula is loose, soft palate is too low, hypertrophy of tonsils) and And 20 time/hour persons of AHI <.But postoperative easy recurrence, and wound is larger, spends higher.Appliance is usually used in simple snore Disease and slight OSAHS patient's (15 times/hour of AHI <), the person that particularly has mandibular retrusion.For not being resistant to CPAP, it is impossible to Operation or surgical effect gastrointestinal disease patient can be tried out, but effectiveness is relatively low.Continuous positive airway (Continuous Positive airway pressure, CPAP) a physiological stress support epithelium healing can be provided, it is ensured that epithelium healing during sleep Opening.But which has a disadvantage that:
It is expensive, popularization is difficult in developing country use;
Equipment instrument is larger, it has not been convenient to carry, especially inconvenient for the personage for often going on business;
3rd, connecting line limits patient at night activity, and compliance is reduced;
4th, continuous positive pressure means that continuous flow is present, and can cause Most patients sense of discomfort, so that considerable trouble Person is not resistant to treatment;
5th, it is poor to central sleep apnea patient therapeutic effect.
The content of the invention
The present invention is in order to solve the above problems, it is proposed that a kind of ventilation of the PEP with external diaphragm pacing function face Cover, the device have external diaphragm pacing function, have good effect to central and obstructive sleep apnea.
To achieve these goals, the present invention is adopted the following technical scheme that:
A kind of PEP Ventilation mask with external diaphragm pacing function, including PEP mask and diaphragm pacing Device, wherein, the PEP mask includes mask and several check valves;Check valve is connected with mask, is inhaled by mask During gas, check valve is opened, and during expiration, closed check valve starts until air-breathing next time, limits gas exhalation, is set up on when exhaling Positive Airway Pressure;The diaphragm pacing device includes sensing unit, diaphragm pacemaker and electrode, and sensing unit includes that air-flow is sensed Device, sound transducer, thorax abdomen motion sensor and oxygen saturation sensor, interface of the sensor unit by respective sensor Connection diaphragm pacemaker, diaphragm pacemaker receive the signal of each sensor input, send corresponding electric pulse, and electrode will be produced Electric impulse signal be input to the phrenic nervess traveling body surface of monitored people.
The pressure limit of the unidirectional valve regulation mask, pressure regulation spectrum are 5~20cmH2O。
The diaphragm pacemaker includes sensor interface module, central processing module, keyboard control module, impulse circuit mould Block, display module and output module, sensor interface module, keyboard control module, pulse circuit module, display module and output Module connects central processing module, and sensor interface module connects each sensor, and the detection signal to sensor carries out mould Number conversion.
The central processing module, the signal incoming to sensor are processed, and are produced output control signal, are transferred to arteries and veins Circuit module is rushed, the signal transmission of pulse circuit module is exported by output module to output module.
The sensing unit includes pneumatic sensor, sound transducer, abdominal exercise sensor and oxygen saturation sensor, The species of concrete sensor carries out unrestricted choice use according to the situation for being detected patient.
The thorax abdomen motion sensor is used to detect patient's thorax abdomen respiratory movement.
The sound transducer detects patient's snore sound.
The pneumatic sensor, is installed on mask, for detecting the respiratory air flow of sufferer.
The oxygen saturation sensor, is fixed at ear-lobe, tip oxygen saturation.
During use, when pneumatic sensor, sound transducer, abdominal exercise sensor and oxygen saturation sensor are detected and slept After dormancy asphyxia, diaphragm pacing module is output control signals to, pulse signal producer sends pulse according to preset program Signal, transmits electric pulse by the electrode near the phrenic nervess of body surface, and phrenic nervess are transferred to diaphram after being irritated by pulse, make diaphragm Flesh shrinks, and breathing recovers normal.PEP Ventilation mask can increase the pressure of pharyngeal airway, maintain pharyngeal airway across wall Barometric gradient.Increase functional residual capacity, and by the regulation of vagal feedback and pulmonary stretch receptor increasing epithelium healing Tension force, reduce air flue and subside, reduce the number of times that asphyxia and low pass gas occur.
Beneficial effects of the present invention are:PEP Ventilation mask with external diaphragm pacing function, to central and Obstructive sleep apnea has good effect, and has the method that continuous positive pressure venti lation, surgical operation and lower jaw are corrected There is no direct therapeutical effect to centric sleep apnea.Directly act on around phrenic nervess as pulse is irritated, wear Mask basic noiselessness, thus the sleep on patient affects very little.
Description of the drawings
Fig. 1 is the face mask structure schematic diagram of the present invention;
Fig. 2 is the structural representation of the diaphragm pacing device of the present invention;
Fig. 3 is the structural representation of the sensing unit of the present invention;
Fig. 4 is the diaphragm pacemaker structural representation of the present invention.
Specific embodiment:
The invention will be further described with embodiment below in conjunction with the accompanying drawings.
As shown in Figure 1 and Figure 2, a kind of PEP Ventilation mask with external diaphragm pacing function, is filled by diaphragm pacing Put and constitute with PEP mask.Diaphragm pacing device includes sensing unit, diaphragm pacemaker and electrode, wherein, sensing unit It is connected with diaphragm pacemaker, diaphragm pacemaker is connected with electrode;The sleep index of correlation of monitored people is adopted by sensing unit Collection, and it is converted into the signal of telecommunication;Central processing portion of the diaphragm pacemaker for system, it is arranged the letter of input according to program Number it is analyzed, and sends electric pulse;The electric impulse signal that pacemaker is produced is input to electrode the diaphram position of monitored people. PEP mask is by mask with partially unidirectional valve group into during air-breathing, small check valve is opened, and reduces inspiratory resistance.List during expiration Close to valve portion, limit gas exhalation, so as to set up end expiratory positive pressure, and remain off until next time that air-breathing is opened Begin.Pressure limit can be adjusted by arranging check valve, pressure regulation spectrum is 5~20cmH2O。
As shown in figure 3, sensing unit includes pneumatic sensor, sound transducer, abdominal exercise sensor or/and oxygen saturation Degree sensor, specific kind of sensor can carry out selection use according to the situation of detected person.
As shown in figure 4, diaphragm pacemaker is by sensor interface module, central processing module, keyboard control module, pulse electricity Road module, display module and output module composition, wherein, sensor interface module, keyboard control module, pulse circuit module, Display module and output module are connected with central processing module respectively.Sensor interface module:For accessing sensor, and will letter Number carry out analog digital conversion;Central processing module:The preset data of the signal incoming to sensor, program are processed, and are produced Output control signal;Keyboard control module:Input through keyboard and process are carried out to diaphragm pacemaker;Pulse circuit module:Pulse is believed Number generator;Display module:The content of central processing module is shown;Output module:According to CPU module It is input into and the signal that pulse circuit module is produced is exported.
The undulatory motion of thorax abdomen when thorax abdomen motion sensor is used to detect patient respiratory.
Sound transducer detects patient's snore sound.
Pneumatic sensor, is installed on mask, for detecting the respiratory air flow of sufferer.
Oxygen saturation sensor, is fixed at ear-lobe, tip oxygen saturation.
During use, when pneumatic sensor, sound transducer, abdominal exercise sensor or/and oxygen saturation sensor are detected To after sleep apnea, diaphragm pacing module is output control signals to, pulse signal producer is sent according to preset program Pulse signal, transmits electric pulse by the electrode near the phrenic nervess of body surface, and phrenic nervess are transferred to diaphram after being irritated by pulse, Contraction of diaphragm, breathing is made to recover normal.PEP Ventilation mask can increase the pressure of pharyngeal airway, maintain pharyngeal airway Transmural pressure power gradient.Increase functional residual capacity, and by the regulation of vagal feedback and pulmonary stretch receptor come on increasing The tension force of air flue, reduces subsiding for air flue, reduces the number of times that asphyxia and low pass gas occur.
Although the above-mentioned accompanying drawing that combines is described to the specific embodiment of the present invention, not to present invention protection model The restriction enclosed, one of ordinary skill in the art should be understood that on the basis of technical scheme those skilled in the art are not The various modifications made by needing to pay creative work or deformation are still within protection scope of the present invention.

Claims (10)

1. a kind of PEP Ventilation mask with external diaphragm pacing function, is characterized in that:Including PEP mask and Diaphragm pacing device, wherein, the PEP mask includes mask and several check valves;Check valve is connected with mask, is led to When crossing mask air-breathing, check valve is opened, and during expiration, closed check valve starts until air-breathing next time, is limited gas exhalation, is set up Epithelium healing malleation during expiration;The diaphragm pacing device includes sensing unit, diaphragm pacemaker and electrode, and sensing unit includes gas Flow sensor, sound transducer, thorax abdomen motion sensor and oxygen saturation sensor, sensor unit pass through respective sensor Interface connection diaphragm pacemaker, diaphragm pacemaker receives the signal of each sensor input, sends corresponding electric pulse, electrode The electric impulse signal of generation is input to into the phrenic nervess traveling body surface of monitored people.
2. a kind of PEP Ventilation mask with external diaphragm pacing function as claimed in claim 1, is characterized in that:Institute The pressure limit of unidirectional valve regulation mask is stated, pressure regulation spectrum is 5~20cmH2O。
3. a kind of PEP Ventilation mask with external diaphragm pacing function as claimed in claim 1, is characterized in that:Institute Stating diaphragm pacemaker includes sensor interface module, central processing module, keyboard control module, pulse circuit module, display mould Block and output module, the connection of sensor interface module, keyboard control module, pulse circuit module, display module and output module Central processing module, sensor interface module connect each sensor, and the detection signal to sensor carries out analog digital conversion.
4. a kind of PEP Ventilation mask with external diaphragm pacing function as claimed in claim 3, is characterized in that:Institute Central processing module is stated, the signal incoming to sensor is processed, produce output control signal, be transferred to impulse circuit mould Block, the signal transmission of pulse circuit module are exported by output module to output module.
5. a kind of PEP Ventilation mask with external diaphragm pacing function as claimed in claim 1, is characterized in that:Institute Sensing unit is stated, wherein the species of concrete sensor carries out unrestricted choice use according to the situation for being detected patient.
6. a kind of PEP Ventilation mask with external diaphragm pacing function as claimed in claim 1, is characterized in that:Institute Thorax abdomen motion sensor is stated for detecting patient's thorax abdomen respiratory movement.
7. a kind of PEP Ventilation mask with external diaphragm pacing function as claimed in claim 1, is characterized in that:Institute Stating sound transducer includes several, is distributed in ward, for detecting patient's snore sound.
8. a kind of PEP Ventilation mask with external diaphragm pacing function as claimed in claim 1, is characterized in that:Institute Pneumatic sensor is stated, is installed on mask, for detecting the respiratory air flow of sufferer.
9. a kind of PEP Ventilation mask with external diaphragm pacing function as claimed in claim 1, is characterized in that:Institute Oxygen saturation sensor is stated, is installed on mask, for detecting the oxygen saturation in mask.
10. a kind of PEP Ventilation mask with external diaphragm pacing function as claimed in claim 1, is characterized in that: The mask is oxygen face mask, is connected with oxygen cylinder.
CN201410716981.XA 2014-11-28 2014-11-28 A kind of PEP Ventilation mask with external diaphragm pacing function Expired - Fee Related CN104353167B (en)

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CN105169542B (en) * 2015-10-23 2018-08-17 北京怡和嘉业医疗科技股份有限公司 Ventilation control device and breathing mask equipment with the ventilation control device
AU2017363345B2 (en) * 2016-11-28 2020-04-16 Med-El Elektromedizinische Geraete Gmbh Respiration monitoring sensor for a laryngeal pacemaker
CN107693916A (en) * 2017-10-26 2018-02-16 山东大学 A kind of exhaled positive pressure nasal mask with remote monitoring function
CN107802936A (en) * 2017-10-26 2018-03-16 山东大学 A kind of exhaled positive pressure nasal mask with nerve stimulation function
CN107789714A (en) * 2017-10-26 2018-03-13 山东大学齐鲁医院 A kind of multi-functional exhaled positive pressure nasal mask
CN108904939A (en) * 2018-07-24 2018-11-30 河南科技大学第附属医院 A kind of Cardiological dual respiration device
CN114983469B (en) * 2022-06-21 2023-04-18 四川大学华西医院 Method and device for respiratory drive assessment by using ultrasound

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