CN104338184B - A kind of medical embedded porous material and preparation method thereof - Google Patents
A kind of medical embedded porous material and preparation method thereof Download PDFInfo
- Publication number
- CN104338184B CN104338184B CN201310319922.4A CN201310319922A CN104338184B CN 104338184 B CN104338184 B CN 104338184B CN 201310319922 A CN201310319922 A CN 201310319922A CN 104338184 B CN104338184 B CN 104338184B
- Authority
- CN
- China
- Prior art keywords
- wire
- porous material
- braid
- nonmetal
- medical embedded
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/04—Metals or alloys
- A61L27/047—Other specific metals or alloys not covered by A61L27/042 - A61L27/045 or A61L27/06
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/04—Metals or alloys
- A61L27/06—Titanium or titanium alloys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/10—Ceramics or glasses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
- A61L27/306—Other specific inorganic materials not covered by A61L27/303 - A61L27/32
Abstract
The invention discloses a kind of medical embedded porous material, including：Wire or nonmetal wire braid and the metal level being compounded on the braid.The medical embedded porous material that the present invention is provided includes the braid and the metal level being compounded on the braid of wire or nonmetal wire, therefore it has aperture of higher porosity and rule, and in the absence of the closed-ended question of porous material internal holes.The invention discloses a kind of preparation method of medical embedded porous material, comprise the following steps：Wire or nonmetal wire are woven into wire or nonmetal wire braid；On the wire or nonmetal wire braid that metal composite is obtained in above-mentioned steps, medical embedded porous material is obtained.Wire or nonmetal wire are woven into wire or nonmetal wire braid by the present invention first, and its aperture is more regular, while can control to obtain morphology controllable after its pattern, then complex metal layer, the controllable medical porous material of the closure degree in hole.
Description
Technical field
The invention belongs to the preparing technical field of porous material, more particularly to a kind of preparation side of medical embedded porous material
Method.
Background technology
Porous material is a kind of by being mutually communicated or blind bore hole constitutes the material of network structure, the border of hole or table
Face is made up of pillar or flat board.Typical pore structure has：A kind of is to assemble the two dimension formed in the plane by a large amount of polygonal holes
Structure；Due to being shaped like being referred to as " honeycomb " material in the hexagonal structure of honeycomb；More generally by a large amount of many
The three-dimensional structure that the hole of face shape is formed in space clustering.If the solid for constituting hole exists only in the border of hole
（Communicated between hole）, then referred to as perforate；If hole surface is also solid, i.e., each hole and surrounding hole are complete
Separate entirely, then referred to as closed pore；And some holes are then half perforate semi-closure holes.
Medical embedded porous material be it is a kind of be used to be implanted into human body, and the tissue such as human skeleton and muscle can give birth to
Porous material is grown into, reaches that part substitutes the purpose that human body damages bone.Medical embedded porous material will connect with skeleton
Near pattern, modulus of elasticity corresponding with skeleton, and can not degrade in human body can not be anti-with tissue
Should, also there is good fatigue resistance can be with good cycling processability.Make as bone tissue wound and bone formation necrosis therapeutic
Porous implantation material, it is desirable to which hole is preferably all connected and is uniformly distributed, or aperture sections are connected and uniform as needed
Distribution, is allowed to both consistent with the bone growth of human body, the weight of material in itself is alleviated again, is made with being adapted to human body implantation
With.
The preparation method of a variety of medical embedded porous materials, such as United States Patent (USP) US005282861A are disclosed in the prior art
In disclose a kind of preparation method of porous tantalum, it is to the effect that prepared with porous, Kong Yukong phases using polyurethane
Logical porous material precursor, then deposits last layer tantalum metal using the method for chemical vapor deposition on the surface of porous material,
Prepare with porous tantalum.But the polyurethane precursor that this method is used, the porous material pattern prepared can not be accurate
Control.
A kind of preparation method using tantalum powder as the porous tantalum of precursor is also disclosed that in Chinese patent CN102205144A, it is first
Tantalum powder slurry is made in the solution and tantalum powder being first configured to using organic binder bond and dispersant, and is cast in polyurethane foam
In, the dispersant removed in polyurethane foam is then dried, to organic binder bond and polyurethane foam under inert gas shielding
Foam body carries out ungrease treatment, and porous sintered body is made in last vacuum-sintering.But this method has equally also used polyurethane
As precursor, the problem of equally existing the closure that can not accurately control pattern and porous tantalum material internal hole can not be avoided.
The content of the invention
In view of this, the technical problem to be solved in the present invention is the provision of a kind of medical embedded porous material and its preparation
Method, the morphology controllable for the medical embedded porous material that the present invention is provided, and in the absence of the closed-ended question of internal holes.
The invention discloses a kind of medical embedded porous material, including：Wire or nonmetal wire braid and it is compounded in
Metal level on the braid.
It is preferred that, the porosity of wire or the nonmetal wire braid is 75%~95%, the wire or non-gold
The aperture for belonging to silk braid is 0.1~1.0mm.
It is preferred that, the thickness of the metal level is 0.01~0.5mm.
It is preferred that, the wire is the one or more in tantalum, niobium or titanium, and the nonmetal wire is graphite, corundum, pottery
Porcelain, quartz or silicon.
It is preferred that, a diameter of 0.01~0.2mm of the wire or nonmetal wire.
It is preferred that, the metal level is tantalum, niobium or titanium.
Compared with prior art, the medical embedded porous material that the present invention is provided includes wire or nonmetal wire braid
And the metal level on above-mentioned braid is compounded in, wherein, due to wire or the morphology controllable of nonmetal wire braid, hole
Closure degree is controllable, therefore, the morphology controllable of obtained medical embedded porous material, and the problem of closed in the absence of hole.
The invention discloses a kind of preparation method of medical embedded porous material, comprise the following steps：
A）Wire or nonmetal wire are woven into wire or nonmetal wire braid；
B）By metal composite in the step A）On obtained wire or nonmetal wire braid, obtain medical embedded many
Porous materials.
It is preferred that, it is described to be woven to 3 D stereo braiding.
It is preferred that, the aperture of wire or the nonmetal wire braid is 0.1~1.0mm, the wire or non-gold
The porosity for belonging to silk braid is 80%~95%.
It is preferred that, it is described to be complex as vapour deposition.
Wire or nonmetal wire are woven into wire or nonmetal wire braid by the present invention first, then by metal composite
On the wire or nonmetal wire braid, you can obtain medical embedded porous material.The present invention first by wire or
Nonmetal wire is woven into wire or nonmetal wire braid, and its aperture is more regular, while its pattern can be controlled, it is to avoid
The problem of closure of internal holes, then obtain morphology controllable after complex metal layer, the controllable medical porous material of the closure degree in hole.
Test result indicates that, the medical embedded aperture of porous material prepared by the present invention is adjustable, and porosity is about 85%.
Brief description of the drawings
Fig. 1 is the photo of the medical embedded porous material prepared in the embodiment of the present invention 1；
Fig. 2 is the medical embedded porous material scanning electron microscope diagram for preparing in the embodiment of the present invention 1；
Fig. 3 is the partial sweep electron microscope picture of the medical embedded porous material prepared in the embodiment of the present invention 1.
Embodiment
For a further understanding of the present invention, the preferred embodiment of the invention is described with reference to embodiment, still
It should be appreciated that these descriptions are intended merely to further illustrate the features and advantages of the present invention, rather than to invention claim
Limitation.
The invention discloses a kind of medical embedded porous material, including：Wire or nonmetal wire braid and it is compounded in
Metal level on the braid.
The medical embedded porous material that the present invention is provided includes the braid of wire or nonmetal wire and is compounded in described
Metal level on braid, therefore it has the aperture of higher porosity and rule, and in the absence of porous material internal holes
Closed-ended question.
All raw materials of the present invention, originate to it and are not particularly limited, commercially buy.
The medical embedded porous material that the present invention is provided, including wire or nonmetal wire braid.The wire or
Non-metal knitted thing refers to the braid obtained with wire or nonmetal wire by knitting skill, and its pattern, aperture, hole are closed
Conjunction degree etc. is controllable.Therefore suitable braiding scheme can be selected according to actual needs, obtain different wire or
The braid of nonmetal wire.Equally, different weaving methods can also be selected, the wire or nonmetal wire of different structure is woven
Braid.The aperture of the braid is not particularly limited the present invention, in actual applications preferably 0.1~1.0mm, more
Preferably 0.2~0.8mm；The structure of the braid is not particularly limited the present invention, preferably porous spatial networks knot
Structure；The method of braiding is not particularly limited the present invention, is preferably the weaving method interlocked up and down.
The material of wire of the present invention is preferably the one or more in tantalum, niobium or titanium, more preferably tantalum, niobium or
Titanium；The diameter of the wire is preferably 0.01~0.2mm, more preferably 0.04~0.15mm；The material of the nonmetal wire
Preferably graphite, corundum, ceramics, quartz or silicon, more preferably graphite or quartz；The diameter of the wire is preferably 0.01~
0.2mm, more preferably 0.04~0.15mm；The porosity of wire or the nonmetal wire braid is preferably 80%~95%,
More preferably 82%~92%.
Medical embedded porous material provided by the present invention, in addition to the metal level being compounded on the braid.This hair
The material of the bright metal level is preferably tantalum, niobium or titanium, more preferably tantalum；The thickness of the metal level is preferably 0.01~
0.5mm, more preferably 0.05~0.3mm；The present invention is particularly limited without other metal level, ripe with those skilled in the art
That knows is used for compound metal level.
The invention provides a kind of preparation method of medical embedded porous material, comprise the following steps：
A）Wire or nonmetal wire are woven into wire or nonmetal wire braid；
B）By metal composite in the step A）On obtained wire or nonmetal wire braid, obtain medical embedded many
Porous materials
All raw materials of the present invention, originate to it and are not particularly limited, commercially buy.
Wire or nonmetal wire are woven into wire or nonmetal wire braid by the present invention first, the wire or
Nonmetal wire diameter is preferably 0.01~0.2mm, more preferably 0.04~0.15mm；The wire is preferably tantalum, niobium or titanium
In one or more, more preferably tantalum, niobium or titanium；The nonmetal wire is preferably graphite, corundum, ceramics, quartz or silicon, more
Preferably graphite or quartz；Wire or the nonmetal wire braid is porous metals silk or nonmetal wire framework, the frame
The part of frame can be similar diamond molecular arrangement structure, or the cube frame structure or triangular pyramid knot in space
Structure；The aperture of the braid is preferably 0.1~1.0mm, more preferably 0.2~0.9mm.
The source of the wire or nonmetal wire is not particularly limited the present invention, with commercially available wire or nonmetallic
The conventional criteria of silk；The mode of braiding is not particularly limited the present invention, and preferably 3 D stereo weaves, its detailed process
Can be：
First broken line shape is suppressed or are processed into the wire or nonmetal wire mould, the length of each small broken line is excellent
Choosing is adjusted according to actual conditions；The wire or nonmetal wire of above-mentioned broken line shape are compiled by the way of interlocking up and down again
It is made into wire or nonmetal wire braid.The single broken line length is preferably 0.1~2mm, more preferably 0.5~1.5mm；
The condition of the braiding is not particularly limited the present invention, with stereo weaving condition well known to those skilled in the art；This
The equipment of the braiding is not particularly limited for invention, with stereo weaving equipment well known to those skilled in the art；This hair
The bright equipment to the compacting tool set is not limited, and pressed metal silk or nonmetallic can be set with well known to those skilled in the art
It is standby；The present invention is not limited the equipment of the processing, and wire is processed or non-with well known to those skilled in the art
The equipment of metal.
On the wire or nonmetal wire braid that the present invention obtains metal composite in above-mentioned steps, obtain medical embedded
Porous material.Compound mode is not particularly limited the present invention, is preferably vapor-deposited；Mode of the present invention to vapour deposition
It is not particularly limited, it is preferred to use chemical vapour deposition mode, detailed process is preferably：
First wire or nonmetal wire braid are placed in vacuum airtight container, argon gas is passed through and heats；Again by low boiling
Point metallic compound is passed through in the closed container in above-mentioned steps with hydrogen and carries out vapor deposition reaction, by metal composite described
On wire or nonmetal wire braid, medical embedded porous material is obtained.The low boiling metallic compound and hydrogen rub
That ratio preferably 1：（1~50）, more preferably 1：（5~45）；The speed that is passed through of the hydrogen is preferably 3~20L/min, more excellent
Elect 5~18L/min as；The temperature of the heating is preferably 800~1250 DEG C, more preferably 1000~1200 DEG C；The gas phase
The time of deposition reaction is preferably 0.5~3 hour, more preferably 1~2.5 hour；The low boiling metallic compound is preferably
Lower boiling tantalum compound, more preferably tantalic chloride.
The closed container is not particularly limited the present invention, preferably quartz ampoule；The present invention does not have to the vacuum
Especially limitation, with the vacuum required by vapor deposition reaction well known to those skilled in the art；The present invention is to the hydrogen
Gas is not particularly limited, with custom requirements well known to those skilled in the art；The present invention is not limited especially the argon gas
System, with the requirement well known to those skilled in the art for vapor deposition reaction protection gas；The present invention is heavy to the gas phase
The other conditions of product reaction are not particularly limited, and the condition of vapor deposition reaction is known with those skilled in the art.
The present invention carries out above-mentioned wire or nonmetal wire braid after vapor deposition reaction, its hot place of progress of preferred pair
Reason, removes hydrogen, medical embedded porous material is finally obtained, so as to increase the toughness of medical embedded porous material.The present invention is right
The heat treatment is not particularly limited, and preferably carries out according to the following steps, and above-mentioned wire or nonmetal wire porous material are placed in
In closed container, vacuumize and heat, finally obtain medical embedded porous material.The temperature of the heating is preferably 700~900
DEG C, more preferably 750~850 DEG C；The time of the heating is preferably 0.5~2 hour, more preferably 0.8~1.7 hour；This
Closed container is not particularly limited for invention, with heat treatment closed container well known to those skilled in the art；The present invention
The condition vacuumized is not particularly limited, with the condition well known to those skilled in the art vacuumized.
The medical embedded aperture of porous material that the present invention is provided is more regular, with higher porosity, in the absence of porous
The closed-ended question in material internal hole.The preparation method of medical embedded porous material provided by the present invention can control medical embedded
The pattern of porous material, it is to avoid the problem of the closures of medical embedded porous material internal holes.Test result indicates that, institute of the present invention
The medical embedded aperture of porous material prepared is adjustable and aperture is regular, and porosity is about 85%.
For a further understanding of the present invention, the preparation side of the polymer micro-filter membrane provided with reference to embodiment the present invention
Method is described in detail, and protection scope of the present invention is not limited by the following examples.
Embodiment 1
By the tantalum wire that a diameter of 0.06mm tantalum wire pressed sizing is broken line shape.Each small broken line length is
0.3mm, then by the above-mentioned tantalum wire suppressed using the stereo weaving mode interlocked up and down, is woven into aperture for 0.4mm, has
The wire braid of 3 D stereo porous framework.Then the porous material precursor that above-mentioned steps are obtained is placed in closed quartz
Guan Zhong, above-mentioned quartz ampoule is vacuumized and argon gas protection is passed through, then the above-mentioned quartz ampoule equipped with porous material precursor is heated to
1000 DEG C of constant temperature.The last mol ratio that is passed through into above-mentioned quartz ampoule is 1:20 tantalic chloride and hydrogen be vapor-deposited instead
Should, the speed that is passed through of hydrogen is 10L/min.After reaction 0.5 hour, to passing through the treated porous material of above-mentioned steps in vacuum
Under the conditions of, it is heated to 800 DEG C and carries out heat treatment 0.5 hour, finally gives medical embedded porous material.
The medical embedded porous material obtained to above-mentioned steps is tested, and is as a result shown, medical embedded porous material table
The compound tantalum layer thickness in face is 0.1mm, and porosity is 90%.
The medical embedded porous material obtained to above-mentioned steps is observed, as a result referring to Fig. 1, and Fig. 1 is implemented for the present invention
The photo of the medical embedded porous material prepared in example 1.
The medical embedded porous material obtained to above-mentioned steps is scanned electron microscope observation, as a result referring to Fig. 2, figure
The 2 medical embedded porous material scanning electron microscope diagram to be prepared in the embodiment of the present invention 1.
The medical embedded porous material obtained to above-mentioned steps carries out partial sweep electron microscope observation, as a result referring to figure
3, Fig. 3 be the partial sweep electron microscope picture of the medical embedded porous material prepared in the embodiment of the present invention 1.
Embodiment 2
By the tantalum wire that a diameter of 0.04mm tantalum wire pressed sizing is broken line shape.Each small broken line length is
0.4mm, then by the above-mentioned tantalum wire suppressed using the stereo weaving mode interlocked up and down, is woven into aperture for 0.6mm, has
The wire braid of 3 D stereo porous framework.Then the porous material precursor that above-mentioned steps are obtained is placed in closed quartz
Guan Zhong, above-mentioned quartz ampoule is vacuumized and argon gas protection is passed through, then the above-mentioned quartz ampoule equipped with porous material precursor is heated to
1100 DEG C of constant temperature.The last mol ratio that is passed through into above-mentioned quartz ampoule is 1:40 tantalic chloride and hydrogen be vapor-deposited instead
Should, the speed that is passed through of hydrogen is 5L/min.After reaction 2 hours, to passing through the treated porous material of above-mentioned steps in vacuum bar
Under part, it is heated to 800 DEG C and carries out heat treatment 1 hour, finally give medical embedded porous material.
The medical embedded porous material obtained to above-mentioned steps is tested, and is as a result shown, medical embedded porous material table
The compound tantalum layer thickness in face is 0.2mm, and porosity is 82%.
Embodiment 3
By niobium silk of a diameter of 0.04mm niobium silk pressed sizing for broken line shape.Each small broken line length is
0.8mm, the above-mentioned niobium silk suppressed then be woven into aperture for 1.0mm, had using the stereo weaving mode interlocked up and down
The wire braid of 3 D stereo porous framework.Then the porous material precursor that above-mentioned steps are obtained is placed in closed quartz
Guan Zhong, above-mentioned quartz ampoule is vacuumized and argon gas protection is passed through, then the above-mentioned quartz ampoule equipped with porous material precursor is heated to
1200 DEG C of constant temperature.The last mol ratio that is passed through into above-mentioned quartz ampoule is 1:40 tantalic chloride and hydrogen be vapor-deposited instead
Should, the speed that is passed through of hydrogen is 5L/min.After reaction 1.5 hours, to passing through the treated porous material of above-mentioned steps in vacuum
Under the conditions of, it is heated to 800 DEG C and carries out heat treatment 1 hour, finally gives medical embedded porous material.
The medical embedded porous material obtained to above-mentioned steps is tested, and is as a result shown, medical embedded porous material table
The compound tantalum layer thickness in face is 0.15mm, and porosity is 92%.
Embodiment 4
A diameter of 0.08mm quartz fibre silk processing is fixed to the quartz fibre silk of broken line shape.Each small folding
Line length is 0.5mm, and the above-mentioned quartz fibre silk processed then is woven into pore-forming using the stereo weaving mode interlocked up and down
Footpath is 0.7mm, the quartz fibre silk braid with 3 D stereo porous framework.Then porous material above-mentioned steps obtained
Precursor is placed in closed quartz ampoule, and above-mentioned quartz ampoule is vacuumized and argon gas protection is passed through, then porous material is housed by above-mentioned
The quartz ampoule of precursor is heated to 1050 DEG C of constant temperature.The last mol ratio that is passed through into above-mentioned quartz ampoule is 1:50 tantalic chloride and hydrogen
Gas carries out vapor deposition reaction, and the speed that is passed through of hydrogen is 1L/min.After reaction 2 hours, to what is treated by above-mentioned steps
Porous material under vacuum, is heated to 800 DEG C and carries out heat treatment 1 hour, finally give medical embedded porous material.
The medical embedded porous material obtained to above-mentioned steps is tested, and is as a result shown, medical embedded porous material table
The compound tantalum layer thickness in face is 0.2mm, and porosity is 86%.
A kind of medical embedded porous material provided by the present invention and preparation method thereof is described in detail above.This
Apply specific example in text to be set forth the principle and embodiment of the present invention, the explanation of above example is to use
Understand the method and its core concept of the present invention in help.It should be pointed out that for those skilled in the art,
Under the premise without departing from the principles of the invention, some improvement and modification can also be carried out to the present invention, these improve and modified
Fall into the protection domain of the claims in the present invention.
Claims (10)
1. a kind of medical embedded porous material, including：Wire or nonmetal wire braid and it is compounded on the braid
Metal level, the metal level is compounded in wire or the nonmetal wire surface of the braid；The wire or nonmetal wire
Braid is porous metals silk or porous non-metallic reel frame, and the structure of the framework is diamond molecular arrangement structure.
2. medical embedded porous material according to claim 1, it is characterised in that wire or the nonmetal wire braiding
The porosity of thing is 75%~95%, and the aperture of wire or the nonmetal wire braid is 0.1~1.0mm.
3. medical embedded porous material according to claim 1, it is characterised in that the thickness of the metal level is 0.01~
0.5mm。
4. medical embedded porous material according to claim 1, it is characterised in that the wire is in tantalum, niobium or titanium
One or more, the nonmetal wire be graphite, corundum, ceramics, quartz or silicon.
5. medical embedded porous material according to claim 1, it is characterised in that the wire or nonmetal wire it is straight
Footpath is 0.01~0.2mm.
6. medical embedded porous material according to claim 1, it is characterised in that the metal level is tantalum, niobium or titanium.
7. a kind of preparation method of medical embedded porous material, comprises the following steps：
A wire or nonmetal wire) are woven into wire or nonmetal wire braid, wire or the nonmetal wire braiding
Thing is porous metals silk or porous non-metallic reel frame, and the structure of the framework is diamond molecular arrangement structure；
B) by metal composite in the step A) on obtained wire or nonmetal wire braid, obtain medical embedded porous material
Material.
8. preparation method according to claim 7, it is characterised in that described to be woven to 3 D stereo braiding.
9. preparation method according to claim 7, it is characterised in that the aperture of wire or the nonmetal wire braid
For 0.1~1.0mm, the porosity of wire or the nonmetal wire braid is 80%~95%.
10. preparation method according to claim 7, it is characterised in that described to be complex as vapour deposition.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310319922.4A CN104338184B (en) | 2013-07-26 | 2013-07-26 | A kind of medical embedded porous material and preparation method thereof |
| PCT/CN2014/082968 WO2015010643A1 (en) | 2013-07-26 | 2014-07-25 | Method for preparation of a medical implant porous material |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310319922.4A CN104338184B (en) | 2013-07-26 | 2013-07-26 | A kind of medical embedded porous material and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104338184A CN104338184A (en) | 2015-02-11 |
| CN104338184B true CN104338184B (en) | 2017-10-27 |
Family
ID=52392749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310319922.4A Expired - Fee Related CN104338184B (en) | 2013-07-26 | 2013-07-26 | A kind of medical embedded porous material and preparation method thereof |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN104338184B (en) |
| WO (1) | WO2015010643A1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105177523B (en) * | 2015-10-28 | 2016-08-31 | 赵德伟 | A kind of medical porous tantalum metal material |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1685861A2 (en) * | 2005-01-28 | 2006-08-02 | Greatbatch, Inc. | Stent coating for eluting medication |
| CN201150579Y (en) * | 2007-12-26 | 2008-11-19 | 上海康德莱企业发展集团有限公司 | Blood vessel weaving stent with outer-layer lobate structure |
| CN102091349A (en) * | 2011-01-27 | 2011-06-15 | 苏州大学 | High-strength biological scaffold material and preparation method thereof |
| CN103083120A (en) * | 2011-10-28 | 2013-05-08 | 宛新建 | Biodegradable polymer knitted support capable of preventing bile duct benign and malignant stricture and manufacture method thereof |
| CN103088310A (en) * | 2013-01-10 | 2013-05-08 | 青岛高泰新材料有限公司 | Method for preparing medical porous tantalum with three-dimensional reticular graphite foam or reticular vitreous carbon |
-
2013
- 2013-07-26 CN CN201310319922.4A patent/CN104338184B/en not_active Expired - Fee Related
-
2014
- 2014-07-25 WO PCT/CN2014/082968 patent/WO2015010643A1/en active Application Filing
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1685861A2 (en) * | 2005-01-28 | 2006-08-02 | Greatbatch, Inc. | Stent coating for eluting medication |
| CN201150579Y (en) * | 2007-12-26 | 2008-11-19 | 上海康德莱企业发展集团有限公司 | Blood vessel weaving stent with outer-layer lobate structure |
| CN102091349A (en) * | 2011-01-27 | 2011-06-15 | 苏州大学 | High-strength biological scaffold material and preparation method thereof |
| CN103083120A (en) * | 2011-10-28 | 2013-05-08 | 宛新建 | Biodegradable polymer knitted support capable of preventing bile duct benign and malignant stricture and manufacture method thereof |
| CN103088310A (en) * | 2013-01-10 | 2013-05-08 | 青岛高泰新材料有限公司 | Method for preparing medical porous tantalum with three-dimensional reticular graphite foam or reticular vitreous carbon |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2015010643A1 (en) | 2015-01-29 |
| CN104338184A (en) | 2015-02-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102743218B (en) | Porous tantalum rod | |
| EP3222748B1 (en) | Medical porous tantalum metal material and preparation method therefor | |
| CN107518962B (en) | A kind of carbon fibre composite artificial bone and preparation method thereof | |
| CN103480043B (en) | Porous medical tantalum implant material and preparation method thereof | |
| DE202004006867U1 (en) | Carbon-based moldings suitable for use as cell culture carrier and rearing systems | |
| KR101742724B1 (en) | Method for manufacturing porous Titanium scaffolds by utilizing freeze casting | |
| CN106310371A (en) | Tantalum-copper coating for bone implantation and preparation method of tantalum-copper coating | |
| CN104974467A (en) | Nano-hydroxyapatite/polyether-ether-ketone composite material and bone repair body as well as preparation method and application thereof | |
| CN104096267B (en) | A kind of medical gradient composites | |
| CN104338184B (en) | A kind of medical embedded porous material and preparation method thereof | |
| RU88953U1 (en) | IMPLANT FOR SURGICAL REPAIR TREATMENT OF BONE DEFECTS | |
| WO2009056567A3 (en) | Process for producing particles loaded with growth factors, and the particles obtained in this way | |
| CN108578018A (en) | The production method of prosthese and prosthese | |
| CN102251138B (en) | Preparation method of nickel titanium foam alloy with double pore structure | |
| KR101239112B1 (en) | Method for Preparing Porous Titanium-Hydroxyapatite Composite | |
| CN105855553B (en) | A kind of preparation method of porous tantalum material for oral cavity implantation | |
| CN105147383B (en) | A kind of porous tantalum metal hollow screw and application thereof | |
| CN103088310A (en) | Method for preparing medical porous tantalum with three-dimensional reticular graphite foam or reticular vitreous carbon | |
| CN104800887A (en) | Porous titanium coating, titanium-containing multi-coating, preparation method and application thereof | |
| KR20150055500A (en) | Porous materials for implant using bulk rods and metal powders and method for preparing thereof | |
| CN106119586B (en) | A kind of preparation method of porous metal material | |
| WO2017190437A1 (en) | Porous tantalum metal screw for fixing broken bone, and application thereof | |
| KR20170041301A (en) | Method for manufacturing porous magnesium composite having superior strength and anticorrosion | |
| CN110408810A (en) | A kind of method of the porous TiO preparation POROUS TITANIUM of calciothermic reduction | |
| KR20140112584A (en) | Similar bone and porous metal structure and method for manufacturing the same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20171027 Termination date: 20180726 |