CN104337573A - Combined diagnosis equipment integrating PET-MRI (positron emission tomography-magnetic resonance imaging) function - Google Patents
Combined diagnosis equipment integrating PET-MRI (positron emission tomography-magnetic resonance imaging) function Download PDFInfo
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- CN104337573A CN104337573A CN201310328464.0A CN201310328464A CN104337573A CN 104337573 A CN104337573 A CN 104337573A CN 201310328464 A CN201310328464 A CN 201310328464A CN 104337573 A CN104337573 A CN 104337573A
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- 238000003745 diagnosis Methods 0.000 title claims abstract description 37
- 238000002595 magnetic resonance imaging Methods 0.000 title abstract description 80
- 238000003384 imaging method Methods 0.000 claims abstract description 40
- 238000012879 PET imaging Methods 0.000 claims abstract description 13
- 238000002600 positron emission tomography Methods 0.000 claims description 49
- 229910052734 helium Inorganic materials 0.000 claims description 6
- 239000001307 helium Substances 0.000 claims description 6
- SWQJXJOGLNCZEY-UHFFFAOYSA-N helium atom Chemical compound [He] SWQJXJOGLNCZEY-UHFFFAOYSA-N 0.000 claims description 6
- 239000007788 liquid Substances 0.000 claims description 6
- 238000005481 NMR spectroscopy Methods 0.000 claims description 4
- 201000010099 disease Diseases 0.000 abstract description 14
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 14
- 210000004872 soft tissue Anatomy 0.000 abstract description 13
- 238000012636 positron electron tomography Methods 0.000 abstract 2
- 238000012831 peritoneal equilibrium test Methods 0.000 abstract 1
- 238000012877 positron emission topography Methods 0.000 abstract 1
- 238000007689 inspection Methods 0.000 description 8
- 230000004927 fusion Effects 0.000 description 5
- 238000000034 method Methods 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 210000001519 tissue Anatomy 0.000 description 4
- 238000013399 early diagnosis Methods 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 238000012552 review Methods 0.000 description 3
- 230000003444 anaesthetic effect Effects 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 238000002591 computed tomography Methods 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 208000014644 Brain disease Diseases 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 210000000133 brain stem Anatomy 0.000 description 1
- 230000004663 cell proliferation Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 description 1
- 229960001231 choline Drugs 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000002059 diagnostic imaging Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
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- 230000007170 pathology Effects 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 239000000700 radioactive tracer Substances 0.000 description 1
- 238000001959 radiotherapy Methods 0.000 description 1
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- 238000001228 spectrum Methods 0.000 description 1
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- 210000001541 thymus gland Anatomy 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
- A61B6/03—Computed tomography [CT]
- A61B6/037—Emission tomography
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physics & Mathematics (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Radiology & Medical Imaging (AREA)
- High Energy & Nuclear Physics (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Optics & Photonics (AREA)
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- Magnetic Resonance Imaging Apparatus (AREA)
Abstract
The invention provides combined diagnosis equipment integrating a PET-MRI (positron emission tomography-magnetic resonance imaging) function and belongs to the field of medical instruments. The combined diagnosis equipment comprises a guide rail, an MRI device and a cylindrical PET imaging device, the MRI device is arranged on the guide rail and used for acquiring images of a patient, the cylindrical PET imaging device is used for acquiring images of the patient, and central line of an imaging hole of the MRI device is coincident with central hole of an imaging hole of the cylindrical PET imaging device. The combined diagnosis equipment combines molecular imaging of PET and soft tissue comparison function imaging, so that disease cells diffused in soft tissue can be imaged, the patient can scan the disease cells in various mode, and PET and MRI images can be collected respectively.
Description
Technical field
The present invention relates to medical instruments field, refer to a kind of Combining diagnosis equipment merging PET-MRI function especially.
Background technology
PET (positron emission tomography) scanner (Positron Emission Tomography, PET) be utilize the medicine such as part and blood flow display agent of the glucose of positron emission body tag, aminoacid, choline, thymus pyrimidine, receptor to be tracer, with anatomic image mode, the metabolism showing body and lesion tissue cell from molecular level, function, blood flow, cell proliferation or receptor distribution situation, it is the clinical diagnostic message that more physiology and pathology aspect are provided.
Nuclear magnetic resonance (Magnetic Resonance Imaging, MRI) be utilize magnetic resonance phenomenon to obtain electromagnetic signal from human body, and reconstruct human body information, the faultage image in any direction can be obtained, three-dimensional volumetric image, even can obtain the four-dimensional image of space-wave spectrum distribution.
PET/MRI combine both can carry out qualitative to focus accurately, can accurately locate again, its diagnosis performance and value for clinical application higher.Be current perfect, the most high-grade Medical Imaging Technology, be referred to as over nearly 20 years in the most important development in diagnosing tumor field.
With PET/CT(Computed Tomography, computed tomography) compare, PET/MRI has a clear superiority in: PET/CT must do whole body CT video picture, location and correction for attenuation, the radiation dose of whole body CT is large, certain harm is caused to human body, is not suitable for health examination and follows up a case by regular visits to check, the better soft tissue contrast of PET/MRI and resolution, check sensitivity and specificity better, setting accuracy is higher; MRI dissect and function information amount larger than CT many, with the complementarity of PET molecular image better, picture quality and diagnosis effect significantly improve.
PET/MRI combines the location to such as disease of brain stem, performs the operation, and radiotherapy is more reliable accurate, makes disease examination rate higher; PET/MRI checks and to check than PET/CT, makes few 1000 times of the X-ray quantities received of those who are investigated, can better protection of the environment and health.
At present, the medical institutions of China generally adopt independently PET equipment and MRI equipment, when needing the result obtaining the diagnosis of PET/MRI image fusion joint, need first to carry out PET respectively to detect and MRI detection, then PET detected image and MRI detected image are carried out fusion treatment, detection mode is comparatively loaded down with trivial details, also have impact on the accuracy of diagnostic result.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of Combining diagnosis equipment merging PET-MRI function, the molecular imaging of PET is combined with soft tissue contrast's functional imaging of MRI, both can carry out imaging to the disease cells spread in soft tissue, patient is scanned under each pattern; PET and MRI image can be collected respectively again; And MRI in art can be realized.
For solving the problems of the technologies described above, embodiments of the invention provide technical scheme as follows:
On the one hand, a kind of Combining diagnosis equipment merging PET-MRI function is provided, comprises:
Guide rail;
Be arranged on described guide rail, for obtaining the nuclear magnetic resonance MRI device of patient image;
Be arranged on described guide rail, for obtaining the drum type brake PET (positron emission tomography) scanner PET imaging device of patient image;
Wherein, the imaging hole centrage of described MRI device overlaps with the imaging hole centrage of described drum type brake PET imaging device.
Further, in such scheme, described MRI device comprise two to be vertically placed on guide rail, can along the superconducting coil of guide rail parallel movement, described PET imaging device is arranged between two superconducting coils.
Further, in such scheme, described two superconducting coils are connected by liquid helium obturator.
Further, in such scheme, described Combining diagnosis equipment also comprises:
For making the vehicle of patient's movement in described imaging hole.
Further, in such scheme, the height of described vehicle is consistent with the height of described imaging hole centrage.
Further, in such scheme, described guide rail is arranged on the ground by cushion.
Further, in such scheme, described guide rail connects ground by foundation bolt through described cushion.
Embodiments of the invention have following beneficial effect:
In such scheme, the molecular imaging of PET is combined with soft tissue contrast's functional imaging of MRI by Combining diagnosis equipment, both can carry out imaging to the disease cells spread in soft tissue, and patient is scanned under each pattern; PET and MRI image can be collected respectively again; And the Combining diagnosis equipment of the present invention of MRI in art can be realized can carry out imaging inspection to the disease cells spread in soft patient tissues, make the early diagnosis of disease more accurate, patient can be made simultaneously to carry out two inspections, decrease the review time of patient; And MRI in art can be realized.
Accompanying drawing explanation
Fig. 1 is the schematic diagram of the PET/MRI Combining diagnosis equipment of the embodiment of the present invention one.
Fig. 2 is the schematic diagram of MRI in the art of the embodiment of the present invention two.
Reference numeral
1 MRI coil 1
2 MRI coils 2
3 PET device
4 vehicles
5 guide rails
Detailed description of the invention
For embodiments of the invention will be solved technical problem, technical scheme and advantage clearly, be described in detail below in conjunction with the accompanying drawings and the specific embodiments.
Embodiments of the invention one provide a kind of Combining diagnosis equipment merging PET-MRI function, the molecular imaging of PET is combined with soft tissue contrast's functional imaging of MRI, both can carry out imaging to the disease cells spread in soft tissue, patient is scanned under each pattern; PET and MRI image can be collected respectively again.
The embodiment of the present invention two is MRI demonstration in art, and shifted out by PET equipment, and increase the distance of MRI two superconducting coils, two superconducting coils wherein forming MRI are connected by liquid helium obturator; Have a working place vertically entered between two superconducting coils, medical personnel can directly enter and contact patient; The spatial dimension that MRI absorbs image is exactly the scope operated on hand, repeatedly patient need not be advanced release in operation, and vehicle can free in and out or depart from magnet coil completely simultaneously, also can insert between magnet by operating chair; Doctor can grasp information in art in real time according to image monitor; Also can match operating microscope, stereotactic apparatus, navigation, anesthetic machine, monitor and special operating theater instruments etc. use.
The Combining diagnosis equipment of the fusion PET-MRI function of the embodiment of the present invention comprises:
Guide rail;
Be arranged on described guide rail, for obtaining the nuclear magnetic resonance MRI device of patient image;
Be arranged on described guide rail, for obtaining the drum type brake PET (positron emission tomography) scanner PET imaging device of patient image;
Wherein, the imaging hole centrage of described MRI device overlaps with the imaging hole centrage of described drum type brake PET imaging device.
Further, described MRI device comprise two to be vertically placed on guide rail, can along the superconducting coil of guide rail parallel movement, two superconducting coils are connected by liquid helium obturator, and described PET imaging device is arranged between two superconducting coils.
Further, described Combining diagnosis equipment also comprises: for making the vehicle of patient's movement in described imaging hole, and the height of described vehicle is consistent with the height of described imaging hole centrage.This vehicle can be automatic conveying device also can be manual vehicle.When this vehicle is automatic conveying device, this vehicle can be robot moving bed also can be mechanical hand.
In an embodiment of the present invention, can produce vibrations due to when PET imaging device and MRI device running, therefore frame is arranged on the ground by cushion.Particularly, frame can connect ground by foundation bolt through cushion.
The molecular imaging of PET is combined with soft tissue contrast's functional imaging of MRI by Combining diagnosis equipment Combining diagnosis equipment of the present invention, both can carry out imaging to the disease cells spread in soft tissue, patient is scanned under each pattern; PET and MRI image can be collected respectively again; And MRI in art can be realized.Combining diagnosis equipment of the present invention can carry out imaging inspection to the disease cells spread in soft patient tissues, makes the early diagnosis of disease more accurate, and patient can be made simultaneously to carry out two inspections, decrease the review time of patient.
Work process below in conjunction with figure and embodiment a pair Combining diagnosis equipment of the present invention describes in detail:
As shown in Figure 1, the Combining diagnosis equipment of fusion PET and MRI function of the present invention, comprise and be arranged on PET device on guide rail 5 and MRI device, MRI device includes MRI coil 1 and MRI coil 2, MRI coil 1 is vertical with MRI coil 2 to be placed on guide rail 5, two superconducting coils are connected by liquid helium obturator, and these two superconducting coils can move along guide rail parallel, and then the intensity in adjustment magnetic field.PET device 3 is positioned in the middle of MRI two coils, and Combining diagnosis equipment also comprises the vehicle 4 of patient's movement between PET device and MRI device; Combining diagnosis equipment only has an imaging hole, and the centrage of the imaging hole of PET device and the imaging hole of MRI two coils coincides, and the height of vehicle 4 is consistent with the height of imaging hole centrage, can left and right translation in imaging hole.In addition, PET device can also shift out from guide rail 5, and MRI device and PET device can separately be used, and the double solenoid MRI after shifting out can realize the function of MRI in art.
When needs of patients does the inspection of PET/MRI, first according to the needs of patient body, MRI coil 1 and MRI coil 2 is moved in parallel by guide rail 5, the magnetic field intensity of MRI device is changed by the distance changed between two MRI coils, after the working condition setting MRI device and PET device, patient is allowed to lie on vehicle 4, along with moving horizontally of vehicle 4, what first patient passed through is MRI coil 2, then be PET device 3, it is finally MRI coil 1, after inspection is complete, successively patient can be released MRI coil 1, PET3, the imaging hole of MRI coil 2.In whole checking process, patient need not move, and just can complete testing process rapidly.
Composition graphs 2 and embodiment two describe in detail to the work process of MRI in art of the present invention: as shown in Figure 2, with the Combining diagnosis equipment of fusion PET and MRI function of the present invention, realize MRI in art.Wherein PET device shifts out, leave the MRI device be arranged on guide rail 5, MRI device includes MRI coil 1 and MRI coil 2, MRI coil 1 is vertical with MRI coil 2 to be placed on guide rail 5, these two superconducting coils are connected by liquid helium obturator, and can moving along guide rail parallel, and then the intensity in adjustment magnetic field.Combining diagnosis equipment also comprises the vehicle 4 of patient's movement between PET device and MRI device; Have a working place vertically entered between two superconducting coils, patient is transported to the formulation position of working place by vehicle 4 as requested, and medical personnel can directly enter working place and operate in fact to patient; The spatial dimension that MRI absorbs image is exactly the scope operated on hand, and in operation, repeatedly patient need not be advanced release, doctor can grasp information in art in real time according to image monitor, adjusts operation plan at any time.Also can match operating microscope, stereotactic apparatus, navigation, anesthetic machine, monitor and special operating theater instruments etc. use, obtains patient's more fully information, makes therapeutic scheme more accurate, obtain more useful therapeutic effect.
The molecular imaging of PET is combined with soft tissue contrast's functional imaging of MRI by Combining diagnosis equipment of the present invention, both can carry out imaging to the disease cells spread in soft tissue, and patient is scanned under each pattern; PET and MRI image can be collected respectively again; And MRI in art can be realized.Combining diagnosis equipment of the present invention can carry out imaging inspection to the disease cells spread in soft patient tissues, makes the early diagnosis of disease more accurate, and patient can be made simultaneously to carry out two inspections, decrease the review time of patient.
The above is the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the prerequisite not departing from principle of the present invention; can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.
Claims (7)
1. merge a Combining diagnosis equipment for PET-MRI function, it is characterized in that, comprising:
Guide rail;
Be arranged on described guide rail, for obtaining the nuclear magnetic resonance MRI device of patient image;
Be arranged on described guide rail, for obtaining the drum type brake PET (positron emission tomography) scanner PET imaging device of patient image;
Wherein, the imaging hole centrage of described MRI device overlaps with the imaging hole centrage of described drum type brake PET imaging device.
2. Combining diagnosis equipment according to claim 1, is characterized in that, described MRI device comprise two to be vertically placed on guide rail, can along the superconducting coil of guide rail parallel movement, described PET imaging device is arranged between two superconducting coils.
3. Combining diagnosis equipment according to claim 2, is characterized in that, described two superconducting coils are connected by liquid helium obturator.
4. Combining diagnosis equipment according to claim 1, is characterized in that, described Combining diagnosis equipment also comprises:
For making the vehicle of patient's movement in described imaging hole.
5. Combining diagnosis equipment according to claim 4, is characterized in that, the height of described vehicle is consistent with the height of described imaging hole centrage.
6. Combining diagnosis equipment according to claim 1, is characterized in that, described guide rail is arranged on the ground by cushion.
7. Combining diagnosis equipment according to claim 6, is characterized in that, described guide rail connects ground by foundation bolt through described cushion.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310328464.0A CN104337573A (en) | 2013-07-31 | 2013-07-31 | Combined diagnosis equipment integrating PET-MRI (positron emission tomography-magnetic resonance imaging) function |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310328464.0A CN104337573A (en) | 2013-07-31 | 2013-07-31 | Combined diagnosis equipment integrating PET-MRI (positron emission tomography-magnetic resonance imaging) function |
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| Publication Number | Publication Date |
|---|---|
| CN104337573A true CN104337573A (en) | 2015-02-11 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310328464.0A Pending CN104337573A (en) | 2013-07-31 | 2013-07-31 | Combined diagnosis equipment integrating PET-MRI (positron emission tomography-magnetic resonance imaging) function |
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| CN (1) | CN104337573A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106923854A (en) * | 2017-03-21 | 2017-07-07 | 泰山医学院 | A kind of comprehensive Quality Control body mould suitable for PET/CT |
| CN108784726A (en) * | 2018-07-18 | 2018-11-13 | 宁波大学 | PET-MRI imaging devices |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050248344A1 (en) * | 2000-04-25 | 2005-11-10 | Shigehide Kuhara | Magnetic resonance imaging involving movement of patient's couch |
| CN101855564A (en) * | 2007-11-09 | 2010-10-06 | 皇家飞利浦电子股份有限公司 | Mr-PET cyclic motion gating and correction |
| WO2012080973A2 (en) * | 2010-12-16 | 2012-06-21 | Koninklijke Philips Electronics N.V. | Apparatus for ct-mri and nuclear hybrid imaging, cross calibration, and performance assessment |
| CN102854480A (en) * | 2011-06-27 | 2013-01-02 | 通用电气公司 | Coil support for a magnetic resonance imaging (MRI) magnet and method of support |
| CN203458471U (en) * | 2013-07-31 | 2014-03-05 | 北京大基康明医疗设备有限公司 | Positron emission tomography (PET)-magnetic resonance imaging (MRI) function integrated combined diagnosis device |
-
2013
- 2013-07-31 CN CN201310328464.0A patent/CN104337573A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050248344A1 (en) * | 2000-04-25 | 2005-11-10 | Shigehide Kuhara | Magnetic resonance imaging involving movement of patient's couch |
| CN101855564A (en) * | 2007-11-09 | 2010-10-06 | 皇家飞利浦电子股份有限公司 | Mr-PET cyclic motion gating and correction |
| WO2012080973A2 (en) * | 2010-12-16 | 2012-06-21 | Koninklijke Philips Electronics N.V. | Apparatus for ct-mri and nuclear hybrid imaging, cross calibration, and performance assessment |
| CN102854480A (en) * | 2011-06-27 | 2013-01-02 | 通用电气公司 | Coil support for a magnetic resonance imaging (MRI) magnet and method of support |
| CN203458471U (en) * | 2013-07-31 | 2014-03-05 | 北京大基康明医疗设备有限公司 | Positron emission tomography (PET)-magnetic resonance imaging (MRI) function integrated combined diagnosis device |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106923854A (en) * | 2017-03-21 | 2017-07-07 | 泰山医学院 | A kind of comprehensive Quality Control body mould suitable for PET/CT |
| CN108784726A (en) * | 2018-07-18 | 2018-11-13 | 宁波大学 | PET-MRI imaging devices |
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Application publication date: 20150211 |
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