CN104324216A - Traditional Chinese medicine for treating insomnia and preparation method thereof - Google Patents

Traditional Chinese medicine for treating insomnia and preparation method thereof Download PDF

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Publication number
CN104324216A
CN104324216A CN201410569532.7A CN201410569532A CN104324216A CN 104324216 A CN104324216 A CN 104324216A CN 201410569532 A CN201410569532 A CN 201410569532A CN 104324216 A CN104324216 A CN 104324216A
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parts
radix
chinese medicine
traditional chinese
grams
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蔺洪俊
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • A61K36/575Magnolia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/739Sanguisorba (burnet)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8967Lilium, e.g. tiger lily or Easter lily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

Abstract

The invention discloses a traditional Chinese medicine for treating insomnia. The traditional Chinese medicine is composed of the following crude medicines in parts by weight: 3-6 parts of divaricate saposhnikovia root, 3-6 parts of radix angelicae, 3-6 parts of scutellaria baicalensis, 10-15 parts of cuttle bone, 10-20 parts of mangnolia officinalis, 10-20 parts of radix bupleuri, 8-10 parts of lilies, 5-6 parts of rhizoma typhonii, 8-10 parts of raw sanguisorba officinalis, 6-9 parts of rhizoma acori graminei and 4-6 parts of radix ophiopogonis. The traditional Chinese medicine disclosed by the invention has efficacies of clearing heat and purging fire, soothing liver and calming adverse-rising energy, nourishing yin and clearing heat, regulating qi and relieving depression, clearing away heart-fire and tranquilizing mind, and regulating liver and spleen; and through a synergistic effect of the traditional Chinese medicinal ingredients, the traditional Chinese medicine is short in curing time, free from recurrence, safe and free from toxic and side effects.

Description

Chinese medicine of a kind of Cure for insomnia and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine, particularly a kind of Chinese medicine and preparation method thereof of Cure for insomnia.
Background technology
Insomnia refers to fall asleep and maybe cannot keep sleep state, cause not having enough sleep, also known as DIMS (DlMS), because a variety of causes causes, difficulty falling asleep, Depth of sleep or frequency are too short, early awakening and the length of one's sleep not enough or of poor quality etc.
Insomnia is one of common clinical disease, though do not belong to critical illness, hinders people orthobiosis, work, study and health, and can increase the weight of or bring out the diseases such as cardiopalmus, the thoracic obstruction, dizzy, headache, apoplexy.Obstinate insomnia, brings long-term misery to patient, even form the dependence to sleeping medicine, and the sleeping medicine of long-term taking can cause iatrogenic disease.
Summary of the invention
In order to make up the deficiencies in the prior art, the invention provides and a kind ofly prepare Chinese medicine that is simple, evident in efficacy and the Cure for insomnia had no side effect.
The present invention is by the following technical solutions:
A Chinese medicine for Cure for insomnia, its special character is: be made up of the crude drug of following parts by weight: Radix Saposhnikoviae 3-6, Radix Angelicae Dahuricae 3-6, Radix Scutellariae 3-6, Os Sepiae 10-15, Cortex Magnoliae Officinalis 10-20, Radix Bupleuri 10-20, Bulbus Lilii 8-10, Rhizoma Typhonii 5-6, Radix Sangusorbae 8-10, Rhizoma Acori Graminei 6-9, Radix Ophiopogonis 4-6.
Optimization formula of the present invention is: be made up of the crude drug of following parts by weight: Radix Saposhnikoviae 5, the Radix Angelicae Dahuricae 5, Radix Scutellariae 4, Os Sepiae 10, Cortex Magnoliae Officinalis 15, Radix Bupleuri 15, Bulbus Lilii 8, Rhizoma Typhonii 5, Radix Sangusorbae 8, Rhizoma Acori Graminei 8, Radix Ophiopogonis 5.
The preparation method of the Chinese medicine of Cure for insomnia of the present invention, comprises the following steps: cleaned by described crude drug, decoct with water twice.Amount of water is 400ml, 200ml, is concentrated into 300ml, filters.
In the present invention, the effect of each crude drug is as follows:
The Radix Angelicae Dahuricae: expelling wind and removing dampness, evacuation of pus granulation promoting, promoting blood circulation and stopping pain.Cure mainly ulcer sores, skin pruritus, leucorrhea with red and white discharge, hemorrhoidal hamorrhage anal fistula, cold-damp is suffered from abdominal pain, scabies, supraorbital bone pain, headache, toothache, nasal sinusitis;
Radix Saposhnikoviae: deliver, dispel the wind, victory is wet.Cure mainly rubella pruritus, discharging fresh blood stool, stomachache is had loose bowels, affection of exogenous wind-cold, headache general pain, rheumatic arthralgia, and joint is ached, tetanus;
Radix Scutellariae: except damp and hot, pathogenic fire purging, hemostasis, antiabortive.Cure mainly carbuncle furuncle, epidemic febrile disease, damp and hot jaundice, upper respiratory tract infection, cough due to lung-heat, pneumonia, dysentery, hemoptysis, conjunctival congestion, frequent fetal movement, hypertension;
Os Sepiae: astringing to arrest bleeding, treating spontaneous emission and leukorrhagia, relieving gastric hyperacidity to alleviate stomachache, removing dampness sore.Cure mainly haematemesis, hematemesis, metrorrhagia, have blood in stool, epistaxis, wound hemorrhage; The emission and spermatorrhea of instability of kidney QI, leucorrhea with red and white discharge; Have a stomachache noisy, belch pantothenic acid; Eczema ulcer.
Cortex Magnoliae Officinalis: circulation of qi promoting removing food stagnancy, dampness is removed full, lowering the adverse QI to relieve asthma.Cure mainly stagnation of QI due to dyspepsia, abdominal distention constipation, retention of dampness in middle-JIAO, gastral cavity painful abdominal mass is vomited and diarrhoea, and expectorant stops up QI rising in reverse order, and fullness in the chest is breathed with cough.
Radix Bupleuri: reconciling superficies and interior, soothing the liver, yang invigorating.Cure mainly alternate attack of chill and fever, fullness in the chest and hypochondriac pain, bitter taste is deaf, headache and dizziness, malaria, lower sharp proctoptosis, menoxenia, uterine prolapse.
Bulbus Lilii: nourishing the lung to arrest cough, clearing away heart-fire for tranquillization.Cure mainly lung expense chronic cough, cough and spit expectorant blood; After calentura, waste heat comes clear, and fidgets due to deficiency is palpitated with fear, staring spells; Beriberi edema.
Rhizoma Typhonii: drying dampness to eliminate phlegm, expelling wind and relieving convulsion, detoxicating and resolving stagnation of pathogens.Cure mainly wind-phlegm caused in the heap soil or fertilizer over and around the roots of air port eye oblique, middle wind-phlegm, hemiplegia, tetanus, headache, rheumatic arthralgia, numb limbs and tense tendons, scrofula tuberculosis, carbuncle of yin nature toxic swelling peppery, venom, infantile convulsion epilepsy, swollen ulcer drug.
Radix Sangusorbae: cooling blood for hemostasis, heat-clearing and toxic substances removing, eliminating carbuncle sore.Cure mainly the haematemesis of various heat in blood, epistaxis, hematuria, have blood in stool, metrorrhagia, dysentery, hemorrhoidal hamorrhage, hemorrhoid, carbuncle, eczema, burn etc.
Rhizoma Acori Graminei: removing dampness is whetted the appetite, eliminating phlegm of having one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae.Not hungry for gastral cavity painful abdominal mass, a mouthful dysentery of keeping silent, coma epilepsy, forgetful deafness.Regulate the flow of vital energy, invigorate blood circulation, loose wind, dries.Control epilepsy, syncope due to accumulation of phlegm, calentura coma, forgetful, deafness with qi stagnation, ambition is unhappy, stomachache, stomachache, anemofrigid-damp arthralgia, swollen ulcer drug, traumatic injury.
Radix Ophiopogonis: YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.For dryness of the lung dry cough, deficiency of YIN consumptive disease is coughed, sore throat pharyngalgia, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, vexed insomnia, dryness of the intestine constipation.
Beneficial effect of the present invention: the present invention take kinds of traditional Chinese medicines as raw material, scientific compatibility, synergism between each crude drug, there is clearing away heat-fire, soothing the liver sending down the abnormal ascending QI, nourishing YIN and clearing away heat, resolving depression of regulating the flow of vital energy, clear away heart-fire allay excitement, effect of regulating the liver and spleen, short treating period, instant effect, treatment rate are high, are worthy to be popularized.
Detailed description of the invention
Embodiment 1:
Chinese medicine component: Radix Saposhnikoviae 3 grams, the Radix Angelicae Dahuricae 3 grams, Radix Scutellariae 3 grams, Os Sepiae 12 grams, Cortex Magnoliae Officinalis 10 grams, Radix Bupleuri 10 grams, Bulbus Lilii 9 grams, Rhizoma Typhonii 5 grams, Radix Sangusorbae 9 grams, Rhizoma Acori Graminei 6 grams, Radix Ophiopogonis 4 grams.
Usage and dosage: described crude drug is cleaned, decocts with water twice, amount of water is 400ml, 200ml, is concentrated into 300ml, filter, every day potion, decoction being taken warmly at twice.
Embodiment 2:
Chinese medicine component: Radix Saposhnikoviae 6 grams, the Radix Angelicae Dahuricae 6 grams, Radix Scutellariae 6 grams, Os Sepiae 15 grams, Cortex Magnoliae Officinalis 20 grams, Radix Bupleuri 20 grams, Bulbus Lilii 10 grams, Rhizoma Typhonii 6 grams, Radix Sangusorbae 10 grams, Rhizoma Acori Graminei 9 grams, Radix Ophiopogonis 6 grams.
Usage and dosage: described crude drug is cleaned, decocts with water twice, amount of water is 400ml, 200ml, is concentrated into 300ml, filter, every day potion, decoction being taken warmly at twice.
Embodiment 3:
Chinese medicine component: Radix Saposhnikoviae 5 grams, the Radix Angelicae Dahuricae 5 grams, Radix Scutellariae 4 grams, Os Sepiae 10 grams, Cortex Magnoliae Officinalis 15 grams, Radix Bupleuri 15 grams, Bulbus Lilii 8 grams, Rhizoma Typhonii 5 grams, Radix Sangusorbae 8 grams, Rhizoma Acori Graminei 8 grams, Radix Ophiopogonis 5 grams.
Usage and dosage: described crude drug is cleaned, decocts with water twice, amount of water is 400ml, 200ml, is concentrated into 300ml, filter, every day potion, decoction being taken warmly at twice.
Embodiment 4: clinical observation
(1) clinical data
The present inventor in 2011 so far, carries out observation treatment to 500 routine patients, and 30 to 70 years old ages, not etc. cure 461 people, cure rate was not up to 92.2%, and effective 20 people, total effective rate is up to 96.2%.
(2) Therapeutic Method
Every day potion, decoction being taken warmly at twice.
(3) efficacy assessment standard
Recovery from illness: the recovery length of one's sleep or Nighttime sleep, at more than 6h, are slept deep; Effective: sleep is clearly better, and the length of one's sleep increases more than 3h, Depth of sleep increases; Effective: symptom alleviates, increase less than 3h before sleep comparatively; Invalid: after treatment, insomnia is not improved or instead adds severe one.
(4) model case
Ma, man, 62 years old, suffers from insomnia 7 years, difficulty falling asleep, dizzy forgetful, and before sleeping, informal dress is with Alprazolamum, and effect is undesirable.In July, 2012 starts to take Chinese medicine of the present invention, every day potion, sooner or later decoction being taken warmly at twice, after taking 20 days, the length of one's sleep obviously extends, and sleep quality increases, energetic after waking up, and continues to take this Chinese medicine and to fully recover after 10 days drug withdrawal, recurrence that so far there are no.
Zhang, female, 56 years old, suffers from insomnia 3 years, and sleeping after falling asleep is no more than two hours, Chang Xing continuous time, and after waking up, spirit is difficult to concentrate, and aprosexia is depressed.In February, 2013 starts to take Chinese medicine of the present invention, every day potion, sooner or later decoction being taken warmly at twice, after taking 15 days, Depth of sleep significantly improves, energetic, continues to take Chinese medicine of the present invention and to fully recover after 10 days drug withdrawal, recurrence that so far there are no.

Claims (3)

1. a Chinese medicine for Cure for insomnia, is characterized in that: be made up of the crude drug of following parts by weight: Radix Saposhnikoviae 3-6, Radix Angelicae Dahuricae 3-6, Radix Scutellariae 3-6, Os Sepiae 10-15, Cortex Magnoliae Officinalis 10-20, Radix Bupleuri 10-20, Bulbus Lilii 8-10, Rhizoma Typhonii 5-6, Radix Sangusorbae 8-10, Rhizoma Acori Graminei 6-9, Radix Ophiopogonis 4-6.
2. the Chinese medicine of Cure for insomnia according to claim 1, is characterized in that: be made up of the crude drug of following parts by weight: Radix Saposhnikoviae 5, the Radix Angelicae Dahuricae 5, Radix Scutellariae 4, Os Sepiae 10, Cortex Magnoliae Officinalis 15, Radix Bupleuri 15, Bulbus Lilii 8, Rhizoma Typhonii 5, Radix Sangusorbae 8, Rhizoma Acori Graminei 8, Radix Ophiopogonis 5.
3. a preparation method for the Chinese medicine of Cure for insomnia according to claim 1 and 2, is characterized in that: cleaned by described crude drug, decoct with water twice, and amount of water is 400ml, 200ml, is concentrated into 300ml, filters.
CN201410569532.7A 2014-10-23 2014-10-23 Traditional Chinese medicine for treating insomnia and preparation method thereof Pending CN104324216A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101703682A (en) * 2009-11-11 2010-05-12 宋爱民 Chinese medicinal preparation for treating insomnia
CN102283999A (en) * 2011-08-08 2011-12-21 许建成 Traditional Chinese medicine preparation for treating insomnia

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101703682A (en) * 2009-11-11 2010-05-12 宋爱民 Chinese medicinal preparation for treating insomnia
CN102283999A (en) * 2011-08-08 2011-12-21 许建成 Traditional Chinese medicine preparation for treating insomnia

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
禄颖: "通调营卫论治失眠及用药规律分析", 《辽宁中医杂志》 *
许映絮等: "失眠的辨证施治及其遣方用药", 《实用中医内科杂志》 *

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Application publication date: 20150204