CN104323870A - Rabbit fixing box for skin stimulus response test and using method for rabbit fixing box - Google Patents

Rabbit fixing box for skin stimulus response test and using method for rabbit fixing box Download PDF

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Publication number
CN104323870A
CN104323870A CN201410673764.7A CN201410673764A CN104323870A CN 104323870 A CN104323870 A CN 104323870A CN 201410673764 A CN201410673764 A CN 201410673764A CN 104323870 A CN104323870 A CN 104323870A
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China
Prior art keywords
rabbit
plate
hole
casing
wound repair
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CN201410673764.7A
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Chinese (zh)
Inventor
付译鋆
胡星友
关国平
王璐
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Donghua University
National Dong Hwa University
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Donghua University
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Priority to CN201410673764.7A priority Critical patent/CN104323870A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D3/00Appliances for supporting or fettering animals for operative purposes

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Husbandry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Testing Of Devices, Machine Parts, Or Other Structures Thereof (AREA)

Abstract

The invention provides a rabbit fixing box for a skin stimulus response test and a using method for the rabbit fixing box. The rabbit fixing box for the skin stimulus response test is characterized by comprising a supporting plate and a box body arranged on the supporting plate; the box body is provided with a back exposing hole for exposing the back of a rabbit. The rabbit fixing box is simple in structure and convenient to use, can be used for quickly and effectively fixing the rabbit, and can keep the back of the rabbit exposed in an experiment, and is particularly suitable for the skin stimulus response test.

Description

A kind of rabbit fixed case for skin wound repair test and using method thereof
Technical field
The invention belongs to biomaterial experiment equipment field, particularly relate to a kind of rabbit fixed case for skin wound repair test and using method thereof.
Background technology
Rabbit is the conventional animal model of skin wound repair test, and rabbit back spinal column both sides of need being in during test are carried out closing and sticked operation, and usually require to stick fixing at least 4h, the even longer time.
In prior art, usually by the mode of manual crawl, pressing, experimental rabbit is controlled by one or several experimenter, carrying out test specimens by another experimenter and stick, then utilizing medical adhesive tape, binder to be fastened to sticking position.But winding dynamics comes from operator's feel completely, if be wound around tension, then may cause the discomfort of experimental rabbit, cause physical signs irregular change, affect experimental result; If be wrapped over pine, then may not have due fixation.Even if the dynamics of winding is suitable, because rabbit has a lively disposition, immovable bandage still likely due to experimental rabbit twisting, bait, lick and the action such as to lick and destroyed, impact experiment is normally carried out.
Therefore, after having laboratory employing to stick, experimental rabbit is put into fixture, to control rabbit activity, avoid testing unexpected termination.Existing experimental rabbit fixture is mainly divided into band, plate, case three class.
Authorization Notice No. is that the Chinese utility model patent of CN 203539475 U describes a kind of rabbit topical, contamination casting harness, comprise be made up of eyelet fabric main part, make meche in front, lock seaming multilamellar gauze, main part side is provided with neck trepanning, the neck cuff be made up of elastic cord and fixing band, multilamellar gauze is formed by several pieces mono layer gauze four side seam systems, can freely load and unload.This utility model simple structure, is convenient to cleaning and sterilizing, can Reusability, safe and effective, convenient-to-running Baoding can be carried out to rabbit, but because casting harness is flexible material, coming off of Baoding thing unavoidably caused due to actions such as scratching, tear and medicine, thus impact experiment accuracy.
Number of patent application is that the Chinese invention patent of 201310466500.X discloses a kind of rabbit binding board, its plate body is provided with U-shaped health holddown groove and leg holddown groove, the side of health holddown groove is provided with health fixed station, opposite side is provided with three fixed station bases, is respectively arranged with leg fixed station, longitudinal bandage platform and horizontal bandage platform.This invention structure is simple, easy to use, can limit rabbit mobility, and height adjustable, but when using, need rabbit side direction be positioned on plate body, be only applicable to the short time operations such as the blood sampling of specific part or injection, be not suitable for back and the long-time Baoding such as stick.
Authorization Notice No. is that the Chinese utility model patent of CN 203790074 U describes one for zooperal fixture, comprise pedestal, supporter and upper cover, supporter top is provided with cervical region embedded groove, upper cover hides supporter and pedestal, form animal neck spatial accommodation between upper cover and supporter animal neck embedded groove, between upper cover, supporter and pedestal, form animal body spatial accommodation.This utility model can reduce the labor intensity of rabbit location, improve the convenience of rabbit location, but because upper cover is solid slab, exposed back can not be provided, be not suitable for the fixing of skin wound repair test, and this device does not consider the problems such as the feed water inlet of rabbit in experimentation and defecate.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of rabbit fixed case for skin wound repair test and using method thereof, described rabbit fixed case can realize effectively fixing fast rabbit, and a rabbit back can be kept in an experiment exposed, be convenient to close stick carrying out smoothly of experimental implementation.Meanwhile, in order to ensure the true and reliable of experimental result, this fixed case is provided with loose temperature hole, crib tank and defecate device, can keep the natural physiological status of experimental rabbit in a long time.
In order to solve the problems of the technologies described above, the invention provides a kind of rabbit fixed case for skin wound repair test, it is characterized in that, comprise supporting disk and be located at the casing on supporting disk, described casing is provided with the hole of being backless for being exposed by the back of rabbit.
Preferably, described casing comprises top board, side plate and base plate, top board is fixed on the upside of side plate, base plate is fixed on the bottom of side plate, described side plate is by front side board, back side panel, left plate and right plate composition, left plate and right plate be arranged in parallel, the front end of left plate and right plate is fixed with front side board, the rear end of left plate and right plate is fixed with back side panel, right side and the right plate of described top board are connected through the hinge, the left side of top board is provided with two snap closes for being fixedly connected with left plate, the described middle part being located at top board for the hole of being backless of being exposed by the back of rabbit, the top of described front side board and the front end of top board have the first dew neck groove and the second dew neck groove, first dew neck groove and the second dew neck groove form the hole that can hold the cervical region of rabbit, the bottom of front side board and the left and right sides, base plate front end are provided with foreleg and stretch out hole, left plate, the bottom of right plate and the bottom rear left and right sides are provided with back leg and stretch out hole, described supporting disk comprises disk body, and the front end of described disk body is provided with for the crib tank of rabbit water supply for food.
More preferably, four drift angles of described disk body are provided with brace table, and casing is located on brace table.
More preferably, described hole of being backless is square.
More preferably, described left plate and right plate are provided with loose temperature hole.
More preferably, described loose Wen Kongwei runs through the square through hole of side plate, distributes radially.
More preferably low, the middle part of described base plate is provided with porus excretorius.
More preferably, described casing also comprises metal grill plate, and be provided with leg on the downside of four drift angles of described base plate, described metal grill plate is located at the downside of described leg and is connected with leg.
More preferably, the material of described supporting disk is water-proof plywood, and the material of casing is transparent organic glass.
More preferably, described first dew neck groove, the second dew neck groove, foreleg stretches out hole and back leg stretches out the outside in hole all with rubber cover.
Present invention also offers the using method of the above-mentioned rabbit fixed case for skin wound repair test, it is characterized in that, comprising:
The first step: the top board opening casing, is positioned in casing by the rabbit being used for skin wound repair test, to make before and after it lower limb stretch out hole and back leg from foreleg respectively and stretches out hole and stretch out, be positioned in the second dew neck groove on front side of cervical region;
Second step: closed roof box, makes the first dew neck groove be placed on rear side of the cervical region of rabbit, closes snap close and is fixedly connected with left plate by top board;
3rd step: through hole of being backless, empirically requires to carry out being correlated with in the back exposed to rabbit and sticks experimental implementation;
4th step: be positioned on supporting disk by the casing being fixed with rabbit, puts into foodstuff and drinking water in crib tank, and ensures that crib tank is positioned at the front lower place of rabbit head;
5th step: after experiment terminates, removes test position successively and sticks thing, opens snap close and top board, take out rabbit, remove casing, the Excreta on cleaning supporting disk.
Compared with prior art, the invention has the beneficial effects as follows:
1, this rabbit fixed case simple structure, easy to use, can realize effectively fixing fast rabbit, and a rabbit back can be kept in an experiment exposed, is particularly useful for skin wound repair test.
2, the build of this rabbit fixed case and experimental rabbit is suitable, and is provided with front and back lower limb and stretches out hole, can make rabbit in experimentation, keep crouching normally standing position gesture, ensure that its extremity can not produce the phenomenon such as muscle spasm, cramp because of fixing of long period.
3, this rabbit fixed case left and right sides plate is provided with loose temperature hole, for running through the square through hole of side plate, distributing radially, can realize the circulation of air and outside air in fixed case, reduces rabbit body temperature to testing the impact caused.
4, this rabbit fixed case is provided with crib tank, can be the living environment that experimental rabbit provides relatively natural, comfortable in experimentation, ensures that experiment is normally carried out, reduces experimental error.
5, this rabbit fixed case has defecate function, and the Excreta that can effectively produce in isolation experiment process, provides the experimental situation of clean hygiene, and is convenient to experimenter's cleaning and sweeps.
Accompanying drawing explanation
Fig. 1 is that the casing of rabbit fixed case for skin wound repair test of the present invention and supporting disk combine schematic diagram;
Fig. 2 is the roof box of rabbit fixed case for skin wound repair test of the present invention schematic diagram when opening;
Fig. 3 is the supporting disk schematic diagram of the rabbit fixed case for skin wound repair test;
Schematic diagram when Fig. 4 is the rabbit fixed case use for skin wound repair test.
Wherein, 1-supporting disk, 11-disk body, 12-brace table, 13-crib tank, 2-casing, 3-top board, 31-be backless hole, 32-first reveals neck groove, 33-hinge, 34-snap close, 4-side plate, 41 second dew neck grooves, 42-foreleg stretches out hole, 43-falls apart warm hole, 5-base plate, 51-back leg stretch out hole, 52-porus excretorius, 53-metal grill plate, 54-leg.
Detailed description of the invention
Below in conjunction with specific embodiment, set forth the present invention further.Should be understood that these embodiments are only not used in for illustration of the present invention to limit the scope of the invention.In addition should be understood that those skilled in the art can make various changes or modifications the present invention, and these equivalent form of values fall within the application's appended claims limited range equally after the content of having read the present invention's instruction.
Embodiment
As shown in Figure 1, the rabbit fixed case for skin wound repair test of the present invention, comprise supporting disk 1 and be located at the casing 2 on supporting disk 1, described casing 2 is provided with the square hole 31 of being backless for being exposed by the back of rabbit.Supporting disk 1 and casing 2 are separable design, casing 2 can be put in supporting disk 1 appropriate position after rabbit fixedly completes.
As shown in Figure 2, described casing 2 comprises top board 3, side plate 4 and base plate 5, top board 3 is fixed on the upside of side plate 4, base plate 5 is fixed on the bottom of side plate 4, described side plate 4 is by front side board, back side panel, left plate and right plate composition, left plate and right plate be arranged in parallel, the front end of left plate and right plate is fixed with front side board, the rear end of left plate and right plate is fixed with back side panel, the right side of described top board 3 is connected by hinge 33 with right plate, can free-open-close, the left side of top board 3 is provided with two snap closes 34 for being fixedly connected with left plate, firm closure can be realized, the described middle part being located at top board 3 for the hole 31 of being backless of being exposed by the back of rabbit, the top of described front side board and the front end of top board 3 have the first dew neck groove 32 and the second dew neck groove 41, first dew neck groove 32 and the second dew neck groove 41 form the hole that can hold the cervical region of rabbit, the bottom of front side board and the left and right sides, base plate front end are provided with foreleg and stretch out hole 42, left plate, the bottom of right plate and the bottom rear left and right sides are provided with back leg and stretch out hole 51,
Described left plate and right plate are provided with loose temperature hole 43, can realize the circulation of air and extraneous air in fixed case, reduce rabbit body temperature to testing the impact caused.Described loose temperature hole 43, for running through the square through hole of side plate 4, distributes radially.The middle part of described base plate 5 is provided with porus excretorius 52.The described length, width and height of casing 2 and the build of experimental rabbit adapt, and the first dew neck groove 32 and the second dew neck groove 41, foreleg stretches out hole 42, back leg stretches out hole 51 size are suitable with experimental rabbit cervical region, front and back lower limb size respectively.
Described casing 2 also comprises metal grill plate 53, and be provided with leg 54 on the downside of four drift angles of described base plate 5, described metal grill plate 53 is located at the downside of described leg 54 and is connected with leg 54.Leave sufficient space between base plate 5 and metal grill plate 53, front and back lower limb can be overed for experimental rabbit, and metal grill plate 53 can the Excreta of effective isolation experiment process generation, for experimental rabbit provides neatly comfortable living environment.
As shown in Figure 3, described supporting disk 1 comprises disk body 11, and the front end of described disk body 11 is provided with for the crib tank 13 of rabbit water supply for food, its height with fixing after experimental rabbit height of head consistent, guarantee rabbit can normally be taken food water inlet in experimentation.Four drift angles of described disk body 11 are provided with brace table 12, and casing 2 is located on brace table 12.
The material of described supporting disk 1 is water-proof plywood, is convenient to cleaning, can Reusability, and the material of casing 2 is transparent organic glass, so that laboratory observation.Described first reveals neck groove 32, second dew neck groove 41, foreleg stretches out hole 42 and back leg stretches out the outside in hole 51 all with rubber cover, to prevent experimental rabbit skin damage.
Present invention also offers the using method of the above-mentioned rabbit fixed case for skin wound repair test, as shown in Figure 4, comprising:
The first step: the top board 3 opening casing 2, is positioned over the rabbit being used for skin wound repair test in casing 2, to make before and after it lower limb stretch out hole 42 and back leg from foreleg respectively and stretches out hole 51 and stretch out, be positioned in the second dew neck groove 41 on front side of cervical region;
Second step: closed roof box 3, makes the first dew neck groove 32 be placed on rear side of the cervical region of rabbit, closes snap close 34 and is fixedly connected with left plate by top board 3;
3rd step: through hole 31 of being backless, empirically requires to carry out being correlated with in the back exposed to rabbit and sticks experimental implementation; In experimentation, rabbit can keep the standing position gesture that crouches normally, stretches out hole 42 and back leg stretch out the extremity stretched out in hole 53 and can not produce the phenomenon such as muscle spasm, cramp because of the fixing of long period from foreleg.
4th step: the casing 2 being fixed with rabbit is positioned on supporting disk 1, puts into foodstuff and drinking water in crib tank 13, and ensure that crib tank 13 is positioned at the front lower place of rabbit head;
5th step: after experiment terminates, removes test position successively and sticks thing, opens snap close 34 and top board 3, take out rabbit, remove casing 2, the Excreta on cleaning supporting disk 1, to use next time.

Claims (10)

1. the rabbit fixed case for skin wound repair test, it is characterized in that, comprise supporting disk (1) and be located at the casing (2) on supporting disk (1), described casing (2) is provided with the hole of being backless (31) for being exposed by the back of rabbit.
2. as claimed in claim 1 for the rabbit fixed case of skin wound repair test, it is characterized in that, described casing (2) comprises top board (3), side plate (4) and base plate (5), top board (3) is fixed on the upside of side plate (4), base plate (5) is fixed on the bottom of side plate (4), described side plate (4) is by front side board, back side panel, left plate and right plate composition, left plate and right plate be arranged in parallel, the front end of left plate and right plate is fixed with front side board, the rear end of left plate and right plate is fixed with back side panel, the right side of described top board (3) is connected by hinge (33) with right plate, the left side of top board (3) is provided with two snap closes (34) for being fixedly connected with left plate, the described middle part being located at top board (3) for the hole of being backless (31) of being exposed by the back of rabbit, the front end of the top of described front side board and top board (3) has the first dew neck groove (32) and the second dew neck groove (41), first dew neck groove (32) and the second dew neck groove (41) form the hole that can hold the cervical region of rabbit, the bottom of front side board and the left and right sides, base plate front end are provided with foreleg and stretch out hole (42), left plate, the bottom of right plate and the bottom rear left and right sides are provided with back leg and stretch out hole (51), described supporting disk (1) comprises disk body (11), the front end of described disk body (11) is provided with for the crib tank (13) of rabbit water supply for food.
3. as claimed in claim 2 for the rabbit fixed case of skin wound repair test, it is characterized in that, four drift angles of described disk body (11) are provided with brace table (12), and casing (2) is located on brace table (12).
4., as claimed in claim 2 for the rabbit fixed case of skin wound repair test, it is characterized in that, described hole of being backless (31) is for square.
5., as claimed in claim 2 for the rabbit fixed case of skin wound repair test, it is characterized in that, described left plate and right plate are provided with loose temperature hole (43).
6., as claimed in claim 2 for the rabbit fixed case of skin wound repair test, it is characterized in that, described loose temperature hole (43), for running through the square through hole of side plate (4), distributes radially.
7., as claimed in claim 2 for the rabbit fixed case of skin wound repair test, it is characterized in that, the middle part of described base plate (5) is provided with porus excretorius (52).
8. as claimed in claim 2 for the rabbit fixed case of skin wound repair test, it is characterized in that, described casing (2) also comprises metal grill plate (53), be provided with leg (54) on the downside of four drift angles of described base plate (5), described metal grill plate (53) is located at the downside of described leg (54) and is connected with leg (54).
9. as claimed in claim 2 for the rabbit fixed case of skin wound repair test; it is characterized in that; the material of described supporting disk (1) is water-proof plywood; the material of casing (2) is transparent organic glass, and described first reveals neck groove (32), the second dew neck groove (41), foreleg stretches out hole (42) and back leg stretches out the outside in hole (51) all with rubber cover.
10. the using method of the rabbit fixed case for skin wound repair test according to any one of claim 2-9, is characterized in that, comprising:
The first step: the top board (3) opening casing (2), the rabbit being used for skin wound repair test is positioned in casing (2), to make before and after it lower limb stretch out hole (42) and back leg from foreleg respectively to stretch out hole (51) and stretch out, be positioned in the second dew neck groove (41) on front side of cervical region;
Second step: closed roof box (3), makes the first dew neck groove (32) be placed on rear side of the cervical region of rabbit, closes snap close (34) and is fixedly connected with left plate by top board (3);
3rd step: through hole of being backless (31), empirically requires to carry out being correlated with in the back exposed to rabbit and sticks experimental implementation;
4th step: the casing (2) being fixed with rabbit is positioned on supporting disk (1), puts into foodstuff and drinking water in crib tank (13), and ensure that crib tank (13) is positioned at the front lower place of rabbit head;
5th step: after experiment terminates, removes that test position sticks thing, open snap close (34) and top board (3) successively, takes out rabbit, removes casing (1), clear up the Excreta on supporting disk (1).
CN201410673764.7A 2014-11-21 2014-11-21 Rabbit fixing box for skin stimulus response test and using method for rabbit fixing box Pending CN104323870A (en)

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CN201410673764.7A CN104323870A (en) 2014-11-21 2014-11-21 Rabbit fixing box for skin stimulus response test and using method for rabbit fixing box

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Application Number Priority Date Filing Date Title
CN201410673764.7A CN104323870A (en) 2014-11-21 2014-11-21 Rabbit fixing box for skin stimulus response test and using method for rabbit fixing box

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105342721A (en) * 2015-12-08 2016-02-24 天津开发区合普工贸有限公司 Phototoxicity exposure experimental animal fixing and protecting device
CN105769376A (en) * 2016-05-20 2016-07-20 齐齐哈尔医学院 Rotary fixer for detecting murine toe swelling
CN105853018A (en) * 2016-05-17 2016-08-17 安徽师范大学 Animal fixation box
CN107890380A (en) * 2017-12-27 2018-04-10 上海市计划生育科学研究所 Animal experiment device
CN108670490A (en) * 2018-06-01 2018-10-19 李辉云 A kind of special treatment of animals shield cage of animal doctor

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CN203790075U (en) * 2014-04-10 2014-08-27 内蒙古民族大学 Anesthesia fixing device for domestic rabbit
CN203790074U (en) * 2014-04-01 2014-08-27 华润双鹤药业股份有限公司 Fixing apparatus for animal experiments

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Publication number Priority date Publication date Assignee Title
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CN105853018A (en) * 2016-05-17 2016-08-17 安徽师范大学 Animal fixation box
CN105769376A (en) * 2016-05-20 2016-07-20 齐齐哈尔医学院 Rotary fixer for detecting murine toe swelling
CN107890380A (en) * 2017-12-27 2018-04-10 上海市计划生育科学研究所 Animal experiment device
CN108670490A (en) * 2018-06-01 2018-10-19 李辉云 A kind of special treatment of animals shield cage of animal doctor

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