CN104304284B - A kind of containing paichongding with the insecticidal synergistic composition of capillary - Google Patents

Abstract

A kind of containing paichongding with the insecticidal synergistic composition of capillary, containing active components A and active component B, active components A refers to paichongding, active component B refers to capillary, wherein active components A is 1: 70～1: 70 with the weight ratio of active component B, its preferred weight ratio is 1: 50～1: 50, and two kinds of active component gross weight percentage composition in the composition is 5%～50%.Combination dosage form is one or more in suspending agent, microemulsion, aqueous emulsion.The present composition can be used for thrips or the aphid of preventing and treating harm multiple kinds of crops.

Description

A kind of containing paichongding with the insecticidal synergistic composition of capillary

Technical field

The present invention relates to a kind of agricultural insecticidal composite, particularly relate to a kind of potentiation containing paichongding and capillary and kill Worm agent compositions, can be used for preventing and treating agricultural pests, particularly thrips and aphid.

Background technology

Paichongding is efficient, the novel nicotinamide insecticide of wide spectrum, low toxicity of Ke Sheng group exploitation, is mainly used in preventing and treating same Wing mesh insect.Imidacloprid is one of insecticide variety of consumption maximum in the world at present, but owing to it uses the most frequently, Through causing significant resistance in the world, and the activity that paichongding antagonism inhales juice class pest is significantly higher than imidacloprid, because of This paichongding is one of preferable kind replacing Imidacloprid Contol ofCotton thrips and aphid.Paichongding chemical name is: 1-((6-chlorine pyrrole Pyridine-3-base) methyl)-5-propoxyl group-7-methyl-8-nitro-1,2,3,5,6,7-hexahydro imidazoles [1,2-a] pyridines.Its molecule is tied Structure formula is:

Capillary, english common name: chlorfenapyr, is new pyrrole compounds, thin in acting on insect bodies On the mitochondrion of born of the same parents, worked by the mixed-functional oxidase in insect bodies, mainly suppress adenosine diphosphate (ADP) (ADP) to three phosphorus The conversion of adenosine monophosphate (ATP), and adenosine triphosphate stored cells maintains energy necessary to its vital functions.This medical instrument has stomach toxicity And action of contace poison.Strong at blade face permeability, there is certain systemic action, and have that insecticidal spectrum is wide, preventive effect is high, holding effect length, safety Feature, can effectively prevent and treat the aphid on vegetable, Cotton Gossypii, thrips etc..Its molecular structural formula is:

At present, the Main Means that pesticide makees agricultural pests as chemical prevention is applied widely.But, life-time service list The pesticide of one kind, easily promotes insect to produce certain resistance, for this peasant household often through using the consumption side increasing the weight of pesticide Formula, to reach to eliminate the purpose of insect.But adopt and exist in this way, environment causes bigger pollution and pesticide residual The problem stayed, improves the drug cost of peasant household simultaneously the most indirectly.

There is not been reported for the complex composition of paichongding and capillary at present.

Summary of the invention

It is an object of the invention to provide a kind of mixed ratio reasonable, prevention effect is good, the Synergistic fertilizer group that drug cost is low Compound.

Another object of the present invention is to the purposes providing this composition pesticide for preventing and treating thrips and aphid.

Technical scheme is as follows: a kind of synergic agricultural pesticide composition, it is characterized in that containing active components A and work Property composition B, active components A refers to that paichongding, active component B refer to capillary, and the weight ratio of active component is 1: 70～1: 70, Preferably weight ratio is 1: 50～1: 50.Composition pesticide of the present invention can be configured to suspend according to method well-known in the art One or more in agent, microemulsion and aqueous emulsion, in preparation, the gross weight percentage composition of effective ingredient is 5%～50%, its Remaining is to allow in pesticide to use and acceptable auxiliary element.

Preparation is prepared in a known manner, it is common that by abundant with surfactant, solvent or solid carrier for active component Mixing or grinding, pelletize.The auxiliary agent used in the compositions of the present invention includes solvent, cosolvent, dispersant, emulsifying agent, moistening Agent, stabilizer, antifreezing agent, thickening agent, defoamer, filler etc. and other be of value to that effective ingredient is stable in the formulation to be sent out with drug effect The known substance waved is all conventional in pesticidal preparations or allows the various compositions used, and is not particularly limited, concrete composition and use Amount is determined by test according to recipe requirements.

Instant component is reasonable, good disinsection effect, and drug cost is low, and active components A and B have significant synergies, Compared with prior art, the beneficial effects of the present invention is: 1. compared with single dose, said composition antagonism insect, such as thrips and Aphid has obvious potentiation, improves prevention effect；2. two kinds of effective ingredient mixtures, decrease dosage, thus reduce Cost and alleviate the pollution to environment；3. compositions is made up of the effective ingredient that two kinds of mechanism of action are different, is conducive to gram Take and delay the Drug resistance of insect；4. it is provided simultaneously with quick-acting and long-acting two major features.

Detailed description of the invention

Below in conjunction with example, the invention will be further described.But the present invention is only limitted to absolutely not these examples.All formula Middle percentage ratio or proportioning are weight percentage or weight ratio.The processing technique of the various preparation of the present composition and equipment are the public Known.

1, the preparation of aqueous emulsion

Being dissolved by active component solvent, stable antifreezing agent, to the most transparent as oil phase, is mixed by addition emulsifier for mixing with water Close homogeneous as aqueous phase.Under 3000～6000 revs/min of shear conditions, oil phase is added slowly in aqueous phase stirring 20～50 Minute, form the aqueous emulsion of favorable dispersibility.

Example of formulations 1:15% paichongding capillary aqueous emulsion

Paichongding (active component) 7%

Capillary (active component) 8%

Trimethylbenzene (solvent) 15%

Sodium alkyl benzene sulfonate (emulsifying agent) 8%

Glycerol (stablizing antifreezing agent) 5%

Water complements to 100%

2, the preparation of microemulsion

Active component solvent, cosolvent are dissolved, add emulsifier for mixing to the most transparent as oil phase, will stablize antifreezing agent Mix homogeneous as aqueous phase with water.Oil phase is slowly dropped in aqueous phase, stirs 30～60 minutes and form the micro-of favorable dispersibility Emulsion.

Example of formulations 2:20% paichongding chlorfenapyr microemulsion

Paichongding (active component) 8%

Capillary (active component) 12%

Acetone (solvent) 15%

DMF (cosolvent) 5%

Phenethyl phenol polyethenoxy ether (emulsifying agent) 10%

Agriculture breast 500# (emulsifying agent) 5%

Ethylene glycol (stablizing antifreezing agent) 2%

Water complements to 100%

3, the preparation of suspending agent

By active component, dispersant, wetting agent, thickening agent and water successively in the ratio mix homogeneously of formula, through sand mill Suspending agent is obtained after grinding.

Example of formulations 3:30% paichongding capillary suspending agent

Paichongding (active component) 10%

Capillary (active component) 20%

Sodium alkyl benzene sulfonate (dispersant) 6%

Alkylphenol polyoxyethylene (wetting agent) 4%

Xanthan gum (thickening agent) 0.3%

Water complements to 100%

Bioassay and test of pesticide effectiveness example:

1, paichongding Toxicity Determination to brown paddy plant hopper compounding with capillary

The former medicine of test medicine paichongding uses the former medicine that Kesheng Group Co., Ltd., Jiangsu Prov. produces, the former medicine of capillary to adopt Former medicine with Xinyi Vinh Long Chemical Co., Ltd..Test method is with reference to " People's Republic of China (PRC) agricultural industry criteria NY/T 1154.11-2008 " former medicinal organic solvent acetone is configured to mother solution after, the twen-80 aqueous solution with 0.1% is by geometric ratio Method 5 series mass concentration of configuration.The aptery aphid of Brassica campestris L that examination worm is indoor feeding, physiological status is consistent.Choose laboratory The consistent Brassica campestris L in seedling stage of stalwartness cultivated, wins blade, dries in the air anhydrous to surface, by blade in the medicament configured at shady and cool Dipping 30s, taking-up is dried, and encases root moisturizing, outsourcing preservative film with absorbent cotton, is placed in test tube, 3, every test tube.Often process 4 Individual repetition, and set the process without medicament and do blank.With pest sucking device, examination worm is moved in test tube, 15, every test tube, the mouth of pipe Cover with gauze.Examination worm after process is placed in temperature (25 ± 1) DEG C, relative humidity 60%～80%, and periodicity of illumination is L: D= Raise and observe under (16: 8) h.

Carry out the toxicity test of mixture according to mixed ratio by single dose toxicity test method.Right with drug concentration (mg/L) Numerical value is independent variable X, with the probability value of corrected mortality for dependent variable Y, sets up virulence regression equation formula respectively, uses DPS soft Part calculates single dose and the LC of each proportioning mixture₅₀, calculate co-toxicity coefficient (CTC) according to the abundant method of Sun Yun.

Co-toxicity coefficient CTC computing formula is as follows: (with paichongding as standard agent, its toxicity index is 100):

The LC of toxicity index (the TI)=paichongding of capillary₅₀The LC of capillary₅₀×100

The LC of actual measurement toxicity index (the ATI)=paichongding of M₅₀The LC of M₅₀×100

TI × P paichongding of theoretical toxicity index (the TTI)=paichongding of M+capillary TI × P capillary

TTI × 100 of the ATI M of co-toxicity coefficient (the CTC)=M of M

In formula: M is the mixture of paichongding and capillary different ratio

P paichongding is the ratio that paichongding is shared in mixture

P capillary is the ratio that capillary is shared in mixture

Joint toxicity measuring result to Brown Planthopper: be shown in Table 1

Table 1, paichongding joint toxicity measuring to rape aphid compounding with capillary

As seen from Table 1, paichongding is compounding with capillary the highest potentiation to rape aphid.Paichongding and capillary When proportioning is 1: 1, co-toxicity coefficient reaches more than 146.

2, paichongding and the capillary various proportioning field efficiency test to soybean thrips.

Trial crops is Semen sojae atricolor, and controlling object is soybean thrips.By uniform to water respectively for embodiment 1,2,3 totally 3 kinds of medicaments Spraying treatment is carried out after dilution, if medicament comparison and blank clear water comparison.Group arrangement in random district between process, every kind processes three weights Multiple.1 day, 3 days and 7 days investigation number of pest after medicine, calculate mortality rate and prevention effect respectively, and result of the test is as shown in table 2.

1d, 3d and 7d field test results to soybean thrips after table 2 different disposal medicine

Note: in table, data are to repeat meansigma methods 3 times.

1st day, 3 days, 1,2,3 pairs of Semen sojae atricolor Jis of 7 days each example of formulations from the result of the test of table 2 it can be seen that after medicine The preventive effect of horse, obviously higher than 10% paichongding suspending agent, the preventive effect of 10% capillary suspending agent two single dose, shows that two kinds of medicaments are multiple Add effect substantially.

3, paichongding and the capillary various proportioning field efficiency test to wheat aphid.

Test controlling object wheat aphid.Spray after embodiment 1,2,3 totally five kinds of medicament dilutions uniform to water respectively Mist processes, if medicament comparison and blank clear water comparison.Group arrangement in random district between process, every kind processes three times and repeats.Respectively at medicine Latter 1 day, 3 days and 7 days investigation number of pest, calculate mortality rate and prevention effect, and result of the test is as shown in table 3.

1d, 3d and 7d field test results to wheat aphid after table 3, different disposal medicine

Note: in table, data are to repeat meansigma methods 3 times.

From the result of the test of table 3 it can be seen that after medicine the 1st day, 3 days, 7 days each example of formulations 1,2,3 are to little wheat aphid The preventive effect of worm, obviously higher than 10% paichongding suspending agent, the preventive effect of 10% capillary suspending agent two single dose, shows that two kinds of medicaments are multiple Add effect substantially.

In sum, the present invention contains the Pesticidal combination of paichongding and capillary, and thrips, aphid are had well preventing and treating Effect, complex preparation not only increases preventive effect, and expands insecticidal spectrum, widens range, reduces cost, to multiple insect pest Play the double effect controlled of a medicine, alleviate manpower and materials, improve productivity effect.So, the invention of this complex preparation and popularization are to society Can have and be of great significance.

Claims (4)

1. a synergic agricultural pesticide composition, it is characterised in that containing active components A and B, active components A refers to paichongding, Active component B refers to that the weight ratio of capillary, active components A and B is 1: 10～5: 1, and two kinds of active component are in the composition Gross weight percentage composition is 5%～50%.

Pesticidal combination the most according to claim 1, it is characterised in that: the preferred weight ratio of active components A and B is 1: 10 ～1: 1.

3. according to the Pesticidal combination described in any one of claim 1 and 2, it is characterised in that: the dosage form of described composition pesticide It it is the one in suspending agent, microemulsion and aqueous emulsion.

4. the purposes in preventing and treating thrips and aphid of the composition pesticide described in any one of claim 1 and 2.