CN104274594A - Traditional Chinese medicine preparation for treating prosopalgia - Google Patents

Traditional Chinese medicine preparation for treating prosopalgia Download PDF

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CN104274594A
CN104274594A CN201410579109.5A CN201410579109A CN104274594A CN 104274594 A CN104274594 A CN 104274594A CN 201410579109 A CN201410579109 A CN 201410579109A CN 104274594 A CN104274594 A CN 104274594A
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徐晓胜
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Abstract

The invention discloses a traditional Chinese medicine preparation for treating prosopalgia. The traditional Chinese medicine preparation respectively comprises the following selected raw material medicines by weight: 10-20g of ligusticum wallichii, 10-20g of radix angelicae, 5-10g of radix aconiti preparata, 10-30g of root of rehmannia, 5-15g of liquorice, 5-15g of rheum officinale (decocted later), 10-20g of caltrop, 10-20g of honeysuckle, 5-15g of fructus aurantii, 5-10g of stiff silkworm, 10-15g of scorpio, 10-20g of felwort, 10-20g of the root of red-rooted salvia and 5-10g of earthworm. The selected medicinal medicines are excellent in compatibility and have the effects of promoting the circulation of qi and eliminating stagnation, expelling wind and removing cold and promoting blood circulation to arrest pain, so that the effects of calming and relieving pain are achieved.

Description

One treats prosopalgic Chinese medicine preparation
Technical field
The invention belongs to the field of Chinese medicines, one can treat prosopalgic Chinese medicine preparation specifically.
Background technology
Trigeminal neuralgia is modal cranial nerve diseases, and with the violent pain of the paroxysmal of recurrent exerbation in a side surface part nervi trigeminus areal area for main manifestations, the sickness rate 52.2/10 ten thousand of domestic statistics, female is slightly more than man, and sickness rate can increase with the age.Trigeminal neuralgia is multiple is born in middle-aged and elderly people, R)L.The feature of this disease is: in Head And Face nervi trigeminus distributed areas, and morbidity is sent out suddenly, all standing, lightning sample, the sample that lancinates, burns sample, intractable, insufferable severity pain.Speak, wash one's face, brush teeth or mild wind strokes face, having an intense pain when all can cause paroxysmal when even walking.Pain lasts several seconds or several minutes, and pain is periodical attack, and the outbreak intermission is the same with normal person.
Trigeminal neuralgia is divided into constitutional and Secondary cases two kinds, and secondary trigeminal neuralgia comprises brain occupying lesion and perstriction, the unknown etiology as yet of primary trigeminal neuralgia, and modern Western medicine also lacks effectively and the therapy had no side effect.Trigeminal neuralgia ordinary person is difficult to stand even overwhelmed with sorrow, therefore answers active treatment.Current doctor trained in Western medicine mainly adopts medicine antagonism and the operative treatments such as carbamazepine, but drug administration is very big to hepatorenal damage, and has the side effect such as drowsiness, dizzy, digestive tract is uncomfortable, and surgical effect is not good yet, and patient is therefore very painful.For removing the misery of the mind & body of patient, according to the principle of tcm syndrome differentiation and treatment, treating both the principal and the secondary aspects of a disease at the same time, we providing a kind of Chinese medicine preparation, being used for the treatment of trigeminal neuralgia and achieving satisfied effect.
Summary of the invention
Instant invention overcomes the technical deficiency existed in treatment trigeminal neuralgia at present, provide a kind of hurtless measure, evident in efficacy, cheap, patient compliance is higher, cure after the prosopalgic Chinese medicine preparation for the treatment of that not easily recurs.
The technical solution adopted in the present invention is:
One treats prosopalgic Chinese medicine preparation, it is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Rhizoma Chuanxiong 10-20 gram, Radix Angelicae Dahuricae 10-20 gram, Radix Aconiti Preparata 5-10 gram, Radix Rehmanniae 10-30 gram, Radix Glycyrrhizae 5-15 gram, Radix Et Rhizoma Rhei 5-15 gram, Fructus Tribuli 10-20 gram, Flos Lonicerae 10-20 gram, Fructus Aurantii 5-15 gram, Bombyx Batryticatus 5-10 gram, Scorpio 10-15 gram, Radix Gentianae 10-20 gram, Radix Salviae Miltiorrhizae 10-20 gram, Pheretima 5-10 gram.
As this kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Rhizoma Chuanxiong 10 grams, the Radix Angelicae Dahuricae 10 grams, Radix Aconiti Preparata 5 grams, 10 grams, the Radix Rehmanniae, 5 grams, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 5 grams, Fructus Tribuli 10 grams, Flos Lonicerae 10 grams, Fructus Aurantii 5 grams, Bombyx Batryticatus 5 grams, Scorpio 10 grams, Radix Gentianae 10 grams, Radix Salviae Miltiorrhizae 10 grams, Pheretima 5 grams.
As this kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Rhizoma Chuanxiong 15 grams, the Radix Angelicae Dahuricae 15 grams, Radix Aconiti Preparata 8 grams, 20 grams, the Radix Rehmanniae, 10 grams, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 10 grams, Fructus Tribuli 15 grams, Flos Lonicerae 15 grams, Fructus Aurantii 10 grams, Bombyx Batryticatus 8 grams, Scorpio 12 grams, Radix Gentianae 15 grams, Radix Salviae Miltiorrhizae 15 grams, Pheretima 8 grams.
As this kind of prioritization scheme:
Described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Rhizoma Chuanxiong 20 grams, the Radix Angelicae Dahuricae 20 grams, Radix Aconiti Preparata 10 grams, 30 grams, the Radix Rehmanniae, 15 grams, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 15 grams, Fructus Tribuli 20 grams, Flos Lonicerae 20 grams, Fructus Aurantii 15 grams, Bombyx Batryticatus 10 grams, Scorpio 15 grams, Radix Gentianae 20 grams, Radix Salviae Miltiorrhizae 20 grams, Pheretima 10 grams.
The instructions of taking of Chinese medicine preparation of the present invention is: after being mixed by the raw material Chinese medicine of above-mentioned weight proportion, 1 dose/day, every agent head decocts the 500ml that adds water, and warm fire boils 25 minutes, extracting juice 250ml; Two decoct the 300ml that adds water, and warm fire boils 20 minutes, extracting juice 150ml.Two decoct mixing, morning and evening decoction being taken hot after meal.15 doses was 1 course for the treatment of.
The raw material Chinese medicine of above-mentioned Chinese medicine preparation:
Rhizoma Chuanxiong, acrid in the mouth, warm in nature; Return liver, gallbladder, pericardium channel.There is blood-activating and qi-promoting, effect of wind-expelling pain-stopping.
The Radix Angelicae Dahuricae, acrid in the mouth, warm in nature; Return stomach, large intestine, lung meridian.There is the cold expelling that induces sweat, wind-expelling pain-stopping, a surname's clearing the nasal passage, dampness leukorrhagia stopping, detumescence and apocenosis effect.
Radix Aconiti Preparata, acrid in the mouth, hardship, hot in nature, poisonous; GUIXIN, liver,kidney,spleen warp.There is expelling wind and removing dampness, effect of antalgic.
The Radix Rehmanniae, sweet in the mouth, hardship, cold in nature; GUIXIN, liver, kidney channel.There is clearing away heat and promoting production of body fluid, removing heat from blood, effect of hemostasis.
Radix Glycyrrhizae, sweet in the mouth, property is put down; GUIXIN, lung, spleen, stomach warp.There is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, effect of coordinating the actions of various ingredients in a prescription.
Radix Et Rhizoma Rhei, bitter in the mouth, cold in nature; Return spleen, stomach, large intestine, liver, pericardium channel.There is heat and toxic materials clearing away, clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation, effect of dampness removing jaundice eliminating.
Fructus Tribuli, acrid in the mouth, hardship, slightly warm in nature, slightly poisonous; Return Liver Channel.There is suppressing the hyperactive liver resolving depression, promoting blood circulation by removing wind, improving eyesight, antipruritic effect.
Flos Lonicerae, sweet in the mouth, cold in nature; Return lung, the heart, stomach warp.There is heat-clearing and toxic substances removing, effect of dispelling wind and heat pathogens.
Fructus Aurantii, bitter in the mouth, pungent, sour, cold nature; Return spleen, stomach warp.There is regulating the flow of QI to ease the stomach, effect of the stagnant relieving distension of row.
Bombyx Batryticatus, salty in the mouth, pungent, property is put down; Return liver, lung, stomach warp.There is expelling wind for relieving convulsion, effect of dissipating phlegm and resolving masses.
Scorpio, acrid in the mouth, property is put down, poisonous; Return Liver Channel.There is endogenous wind stopping spasmolytic, removing obstruction in the collateral to relieve pain, effect of dispersing pathogen accumulation.
Radix Gentianae, bitter in the mouth, cold in nature; Return lung, Liver Channel.There is removing heat-phlegm, relieving cough and asthma, detoxification and promoting urination, effect of cooling blood for hemostasis.
Radix Salviae Miltiorrhizae, bitter in the mouth, cold nature; GUIXIN, Liver Channel.Have blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, clear away heart-fire relieving restlessness, effect of removing heat from blood eliminating carbuncle.
Pheretima, salty in the mouth, cold in nature; Return liver, spleen, urinary bladder channel.Have heat clearing away arresting convulsion, dredging collateral, relievings asthma, effect of diuresis.
Trigeminal neuralgia belongs to the traditional Chinese medical science " wind syndrome of head " or " migraine " category.Interior through cloud: " pathogenic wind follow wind bow on then for headache caused by pathogenic wind, visible severe headache ".Stagnation of QI due to depression of the liver, strongly fragrant fire-transformation of a specified duration, burning hot pneumatic wind-fire folder expectorant is disturbed and causes Qingyang and must not unfold, head is that all sun only can.A vital organs of the human body elite QI and blood all on gather in head, all pathogens, wind, fire, phlegm-damp, blood visitor in meridians, stagnation of phlegm blood stasis, qi stagnation hemagglutination, rent hold back meridians " stagnation of QI and blood may bring about pain ".Therefore treating primary disease should according to the Symptoms of patient, and with activating QI to alleviate the depression, promoting blood circulation and stopping pain, dialectical treatment, applies in a flexible way, and Fang Xianqi is imitated.
In Chinese medicine preparation of the present invention, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Radix Aconiti Preparata, Scorpio can dredging collateral spasmolytic, wind-expelling pain-stopping; The Radix Rehmanniae, Radix Et Rhizoma Rhei, Fructus Tribuli, Radix Gentianae, Radix Salviae Miltiorrhizae can blood circulation promoting and blood stasis dispelling, stimulates the menstrual flow and dispels the wind; Radix Glycyrrhizae, Flos Lonicerae, Fructus Aurantii, Bombyx Batryticatus, Pheretima can heat-clearing and toxic substances removing, and dredging collateral is calmed the frightened.Full side's compatibility is superior, attacks benefit and executes mutually, treating both the principal and secondary aspects of a disease, has given full play to the advantage that differential diagnosis in tcm treats, has been used for the treatment of trigeminal neuralgia, has activating QI to alleviate the depression, the merit that relieving rheumatism and cold, invigorating blood circulation and stopping pains, to disappear the effect of pain to reach calmness, clinic promotion and application.
For investigating clinical efficacy and the safety of medicine of the present invention further, we select the routine out-patient of certain hospital 60 to carry out clinical trial, man 28 example, female 32 example; Minimum 32 years old of age, maximum 48 years old, average 39 years old; The course of disease is the shortest 1 year, the longest 5 years, average 2.5 years; Primary patient 26 example, Secondary cases patient 34 example.
Criterion of therapeutical effect:
Cure: clinical symptoms, sign disappear completely.
Effective: clinical symptoms, sign obviously alleviate.
Effective: clinical symptoms, sign slightly alleviated.
Invalid: clinical symptoms, sign all remain unchanged, do not improve completely.
Therapeutic Method:
After being mixed by the raw material Chinese medicine of above-mentioned weight proportion, add water fried, every agent head decocts the 500ml that adds water, and warm fire boils 25 minutes, extracting juice 250ml; Two decoct the 300ml that adds water, and warm fire boils 20 minutes, extracting juice 150ml.Two decoct mixing, every day 1 dose, point morning and evening 2 decoction being taken hot.15 doses was 1 course for the treatment of.
Efficacy result:
1. clinical efficacy result:
After treatment, cure 28 examples, effective 15 examples, effective 12 examples, invalid 5 examples; Cure rate 46.7%, obvious effective rate 25%, effective percentage 20%, inefficiency 8.3%, total effective rate 91.7%.Those benefits in detail the results are shown in following table 1.
Table 1: clinical efficacy result table after treatment
Number of cases Cure n (%) Effective n (%) Effective n (%) Invalid n (%) Effective percentage n (%)
60 28(46.7) 15(25) 12(20) 5(8.3) 55(91.7)
2. classifying type disease efficacy result:
After treatment, statistics finds, primary trigeminal neuralgia effective percentage is 88.5%, and secondary trigeminal neuralgia effective percentage is 93.4%, can treat in trigeminal neuralgia by Chinese medicine preparation of the present invention, curative effect is secondary trigeminal neuralgia > primary trigeminal neuralgia.Detailed results sees the following form 2.
Table 2: classifying type disease efficacy result synopsis
Disease title Number of cases n Cure n Effective n Effective n Invalid n Effective percentage (%)
Primary trigeminal neuralgia 26 12 5 6 3 88.5
Secondary trigeminal neuralgia 34 16 10 6 2 94.1
3. side effect reaction
In the treatment, all there is not obvious adverse reaction in all patients.
Result shows, Chinese medicine preparation of the present invention, by Chinese medicine differential diagnosis of diseases and the dialectical principle combined, is attacked to mend and doublely to be made, treating both the principal and the secondary aspects of a disease at the same time, is used for the treatment of that trigeminal neuralgia is remarkable, cure rate is high and not easily recurs, having certain advantage, clinic promotion and application.
Detailed description of the invention
Embodiment 1: one treats prosopalgic Chinese medicine preparation, chooses Rhizoma Chuanxiong 10 grams, the Radix Angelicae Dahuricae 10 grams, Radix Aconiti Preparata 5 grams, 10 grams, the Radix Rehmanniae, 5 grams, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 5 grams, Fructus Tribuli 10 grams, Flos Lonicerae 10 grams, Fructus Aurantii 5 grams, Bombyx Batryticatus 5 grams, Scorpio 10 grams, Radix Gentianae 10 grams, Radix Salviae Miltiorrhizae 10 grams, Pheretima 5 grams.
Embodiment 2: one treats prosopalgic Chinese medicine preparation, chooses Rhizoma Chuanxiong 15 grams, the Radix Angelicae Dahuricae 15 grams, Radix Aconiti Preparata 8 grams, 20 grams, the Radix Rehmanniae, 10 grams, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 10 grams, Fructus Tribuli 15 grams, Flos Lonicerae 15 grams, Fructus Aurantii 10 grams, Bombyx Batryticatus 8 grams, Scorpio 12 grams, Radix Gentianae 15 grams, Radix Salviae Miltiorrhizae 15 grams, Pheretima 8 grams.
Embodiment 3: one treats prosopalgic Chinese medicine preparation, chooses Rhizoma Chuanxiong 20 grams, the Radix Angelicae Dahuricae 20 grams, Radix Aconiti Preparata 10 grams, 30 grams, the Radix Rehmanniae, 15 grams, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 15 grams, Fructus Tribuli 20 grams, Flos Lonicerae 20 grams, Fructus Aurantii 15 grams, Bombyx Batryticatus 10 grams, Scorpio 15 grams, Radix Gentianae 20 grams, Radix Salviae Miltiorrhizae 20 grams, Pheretima 10 grams.
Below by concrete case, Chinese medicine preparation curative effect of the present invention is verified further:
Case 1
History XX, female, 38 years old.Patient's readme front left side surface part and head from 3 years have an intense pain, similar electric shock.Take western medicine 2 years half, have no effective.More so, women's head-ornaments severe pain also causes vomiting in recently-moon outbreak.Have the psychology of trying in arms and take Chinese medicine preparation of the present invention, after taking medicine 1 month, readme symptom obviously alleviates, and continues to take 6 months transference cures altogether with medicine of the present invention.Follow up a case by regular visits to and have no a recurrence in.
Case 2
Liu XX, man, 46 years old.Patient was diagnosed as right side trigeminal neuralgia by local hospital before 2 years, and invalid more than the acupuncture and moxibustion therapy moon, took the effect such as carbamazepine, red precious Toutong Capsule all not obvious, during outbreak, pain difficulty is invited.For eliminating misery as early as possible, take Chinese medicine preparation of the present invention voluntarily, after 1 two weeks of taking medicine, readme symptom obviously alleviates, and continues to take 4 months transference cures altogether with medicine of the present invention.Follow up a case by regular visits to and have no a recurrence in.

Claims (4)

1. treat a prosopalgic Chinese medicine preparation, it is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Rhizoma Chuanxiong 10-20 gram, Radix Angelicae Dahuricae 10-20 gram, Radix Aconiti Preparata 5-10 gram, Radix Rehmanniae 10-30 gram, Radix Glycyrrhizae 5-15 gram, Radix Et Rhizoma Rhei 5-15 gram, Fructus Tribuli 10-20 gram, Flos Lonicerae 10-20 gram, Fructus Aurantii 5-15 gram, Bombyx Batryticatus 5-10 gram, Scorpio 10-15 gram, Radix Gentianae 10-20 gram, Radix Salviae Miltiorrhizae 10-20 gram, Pheretima 5-10 gram.
2. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Rhizoma Chuanxiong 10 grams, the Radix Angelicae Dahuricae 10 grams, Radix Aconiti Preparata 5 grams, 10 grams, the Radix Rehmanniae, 5 grams, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 5 grams, Fructus Tribuli 10 grams, Flos Lonicerae 10 grams, Fructus Aurantii 5 grams, Bombyx Batryticatus 5 grams, Scorpio 10 grams, Radix Gentianae 10 grams, Radix Salviae Miltiorrhizae 10 grams, Pheretima 5 grams.
3. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Rhizoma Chuanxiong 15 grams, the Radix Angelicae Dahuricae 15 grams, Radix Aconiti Preparata 8 grams, 20 grams, the Radix Rehmanniae, 10 grams, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 10 grams, Fructus Tribuli 15 grams, Flos Lonicerae 15 grams, Fructus Aurantii 10 grams, Bombyx Batryticatus 8 grams, Scorpio 12 grams, Radix Gentianae 15 grams, Radix Salviae Miltiorrhizae 15 grams, Pheretima 8 grams.
4. Chinese medicine preparation according to claim 1, is characterized in that, described Chinese medicine preparation is made up of the Chinese herb of following weight portion:
Rhizoma Chuanxiong 20 grams, the Radix Angelicae Dahuricae 20 grams, Radix Aconiti Preparata 10 grams, 30 grams, the Radix Rehmanniae, 15 grams, Radix Glycyrrhizae, Radix Et Rhizoma Rhei 15 grams, Fructus Tribuli 20 grams, Flos Lonicerae 20 grams, Fructus Aurantii 15 grams, Bombyx Batryticatus 10 grams, Scorpio 15 grams, Radix Gentianae 20 grams, Radix Salviae Miltiorrhizae 20 grams, Pheretima 10 grams.
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CN1108114A (en) * 1994-04-05 1995-09-13 戚嘉和 Traditional Chinese medicinal prepn. for treating trifacial neuralgia
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CN102078518A (en) * 2009-12-01 2011-06-01 赵莉 Traditional Chinese medicine composition for treating trigeminal neuralgia

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