CN104258256A - 治疗鼻炎、鼻窦炎的中药组合物 - Google Patents

治疗鼻炎、鼻窦炎的中药组合物 Download PDF

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CN104258256A
CN104258256A CN201410524463.8A CN201410524463A CN104258256A CN 104258256 A CN104258256 A CN 104258256A CN 201410524463 A CN201410524463 A CN 201410524463A CN 104258256 A CN104258256 A CN 104258256A
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张建军
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Shandong University of Technology
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Abstract

本发明属于中药制剂领域,具体涉及一种治疗鼻炎、鼻窦炎的中药组合物。所述的中药组合物由以下质量的中药原料制成:石菖蒲6-9克,百合6-9克,山楂50-60克,木香27-33克,麻黄4-8克,金银花4-8克,连翘4-8克,决明子9-12克,桂枝6-9克,防风6-9克,荆芥6-9克,白芷6-9克,辛夷9-12克,苍耳子12-18克,陈皮9-12克,砂仁6-9克,白术6-9克,茯苓6-9克,薄荷2-6克,鸡血藤9-12克,川芎9-12克,红花6-9克,桔梗6-9克,麦冬6-9克。本发明不仅利肺开窍、清热解表、利水散瘀、醒脾升阳、化痰理气,而且价格低廉、不易复发、使用方便。

Description

治疗鼻炎、鼻窦炎的中药组合物
技术领域
本发明属于中药制剂领域,具体涉及一种治疗鼻炎、鼻窦炎的中药组合物。
背景技术
鼻炎即鼻腔炎性疾病,是病毒、细菌、变应原、各种理化因子以及某些全身性疾病引起的鼻腔黏膜的炎症。鼻炎的主要病理改变是鼻腔黏膜充血、肿胀、渗出、增生、萎缩或坏死等。鼻炎的典型症状主要有以下几个方面:(1)鼻塞:鼻塞特点为间歇性。在白天、天热、劳动或运动时鼻塞减轻,而夜间,静坐或寒冷时鼻塞加重。鼻塞的另一特点为交替性。如侧卧时,居下侧之鼻腔阻塞,上侧鼻腔通气良好。由于鼻塞,间或有嗅觉减退、头痛、头昏、说话呈闭塞性鼻音等症状。(2)多涕:常为黏液性或黏脓性,偶成脓性。脓性多于季发性感染后出现。(3)嗅觉下降:多为两种原因所致,一为鼻黏膜肿胀、鼻塞,气流不能进入嗅觉区域;二为嗅区黏膜受慢性炎症长期刺激,嗅觉功能减退或消失。(4)头痛、头昏:慢性鼻窦炎多表现为头沉重感。(5)全身表现:多数人有头痛、食欲不振、易疲倦、记忆力减退及失眠等。
鼻窦炎包括急性鼻旁窦炎和慢性鼻旁窦炎,为鼻科常见疾病,慢性者居多,其中上颌窦最为常见。鼻旁窦炎可发生于一侧,亦可双侧。可限于一窦发病,亦可累及多窦。
现有技术中治疗鼻炎、鼻窦炎的药物很多,但是存在疗程长、易复发、费用高等等缺陷。
发明内容
本发明的目的是提供一种利肺开窍、清热解表、利水散瘀、醒脾升阳、化痰理气的治疗鼻炎、鼻窦炎的中药组合物。
本发明所述的治疗鼻炎、鼻窦炎的中药组合物,由以下质量的中药原料制成:
石菖蒲6-9克,百合6-9克,山楂50-60克,木香27-33克,麻黄4-8克,金银花4-8克,连翘4-8克,决明子9-12克,桂枝6-9克,防风6-9克,荆芥6-9克,白芷6-9克,辛夷9-12克,苍耳子12-18克,陈皮9-12克,砂仁6-9克,白术6-9克,茯苓6-9克,薄荷2-6克,鸡血藤9-12克,川芎9-12克,红花6-9克,桔梗6-9克,麦冬6-9克。
优选由以下质量的中药原料制成:
石菖蒲6克,百合6克,山楂60克,木香30克,麻黄6克,金银花6克,连翘6克,决明子9克,桂枝6克,防风6克,荆芥6克,白芷6克,辛夷9克,苍耳子15克,陈皮9克,砂仁6克,白术9克,茯苓9克,薄荷3克,鸡血藤9克,川芎9克,红花6克,桔梗6克,麦冬6克。
其制备方法按照常规的中药汤剂制备即可,也可以按照常规制法制成丸剂或口服液。优选中药汤剂。
本发明药理作用如下:
石菖蒲:化湿开胃,开窍豁痰,醒神益智。用于脘痞不饥,噤口下痢,神昏癫痫,健忘耳聋。理气,活血,散风,去湿。治癫痫,痰厥,热病神昏,健忘,气闭耳聋,心胸烦闷,胃痛,腹痛,风寒湿痹,痈疽肿毒,跌打损伤。
百合:甘微苦,平。润肺止咳,清心安神。治肺费久嗽,咳唾痰血;热病后余热来清,虚烦惊悸,神志恍惚;脚气浮肿。
山楂:酸、甘,微温。归脾、胃、肝经。消食健胃,行气散瘀,化浊降脂。用于肉食积滞,胃脘胀满,泻痢腹痛,瘀血经闭,产后瘀阻,心腹刺痛,胸痹心痛,疝气疼痛,高脂血症。用于肉食积滞,泻痢不爽。
木香:辛、苦,温。归脾、胃、大肠、三焦、胆经。行气止痛,健脾消食。用于胸胁、脘腹胀痛,泻痢后重,食积不消,不思饮食。煨木香实肠止泻。用于泄泻腹痛。
麻黄:辛、微苦,温。归肺、膀胱经。发汗散寒,宣肺平喘,利水消肿。用于风寒感冒,胸闷喘咳,风水浮肿。蜜麻黄润肺止咳。多用于表证已解,气喘咳嗽。
金银花:甘,寒。归肺、心、胃经。清热解毒,疏散风热。用于痈肿疗疮,喉痹,丹毒,热毒血痢,风热感冒,温病发热。
连翘:清热,解毒,散结,消肿。
决明子:甘、苦、咸,微寒。归肝、大肠经。清热明目,润肠通便。用于目赤涩痛,羞明多泪,头痛眩晕,目暗不明,大便秘结。
桂枝:辛、甘,温。归心、肺、膀胱经。发汗解肌,温通经脉,助阳化气,平冲降气。用于风寒感冒,脘腹冷痛,血寒经闭,关节痹痛,痰饮,水肿,心悸,奔豚。
防风:辛、甘,微温。归膀胱、肝、脾经。祛风解表,胜湿止痛,止痉。用于感冒头痛,风湿痹痛,风疹瘙痒,破伤风。
荆芥:辛,微温。归肺、肝经。解表散风,透疹,消疮。用于感冒,头痛,麻疹,风疹,疮疡初起。
白芷:辛,温。归胃、大肠、肺经。解表散寒,祛风止痛,宣通鼻窍,燥湿止带,消肿排脓。用于感冒头痛,眉棱骨痛,鼻塞流涕,鼻鼽,鼻渊,牙痛,带下,疮疡肿痛。
辛夷:辛,温。归肺、胃经。散风寒,通鼻窍。用于风寒头痛,鼻塞流涕,鼻鼽,鼻渊。
苍耳子:辛、苦,温;有毒。归肺经。散风寒,通鼻窍,祛风湿。用于风寒头痛,鼻塞流涕,鼻鼽,鼻渊,风疹瘙痒,湿痹拘挛。
陈皮:苦、辛,温。归肺、脾经。理气健脾,燥湿化痰。用于脘腹胀满,食少吐泻,咳嗽痰多。
砂仁:辛,温。归脾、胃、肾经。化湿开胃,温脾止泻,理气安胎。用于湿浊中阻,脘痞不饥,脾胃虚寒,呕吐泄泻,妊娠恶阻,胎动不安。
白术:苦、甘,温。归脾、胃经。健脾益气,燥湿利水,止汗,安胎。用于脾虚食少,腹胀泄泻,痰饮眩悸,水肿,自汗,胎动不安。
茯苓:甘、淡,平。归心、肺、脾、肾经。利水渗湿,健脾,宁心。用于水肿尿少,痰饮眩悸,脾虚食少,便溏泄泻,心神不安,惊悸失眠。
薄荷:辛,凉。归肺、肝经。疏散风热,清利头目,利咽,透疹,疏肝行气。用于风热感冒,风温初起,头痛,目赤,喉痹,口疮,风疹,麻疹,胸胁胀闷。
鸡血藤:味苦微甘、性温,归肝、心、肾经;色赤入血,质润行散;具有活血舒筋,养血调经的功效;主治风湿痹痛,手足麻木,肢体瘫痪,月经不调,经行不畅,痛经,经闭,白细胞减少症。
川芎:辛,温。归肝、胆、心包经。活血行气,祛风止痛。用于胸痹心痛,胸胁刺痛,跌扑肿痛,月经不调,经闭痛经,瘕瘕腹痛,头痛,风湿痹痛。
红花:辛,温。归心、肝经。活血通经,散瘀止痛。用于经闭,痛经,恶露不行,瘾瘕痞块,胸痹心痛,瘀滞腹痛,胸胁刺痛,跌扑损伤,疮疡肿痛。
桔梗:苦、辛,平。归肺经。宣肺,利咽,祛痰,排脓。用于咳嗽痰多,胸闷不畅,咽痛音哑,肺痈吐脓。
麦冬:甘,微苦,微寒。归心、肺、胃经。养阴生津,润肺清心。用于肺燥干咳。虚痨咳嗽,津伤口渴,心烦失眠,内热消渴,肠燥便秘;咽白喉。
本发明疗效判断如下:
治愈:临床症状消失,无阳性体质,两年内无复发。
有效:临床症状改善,主要症状明显减轻。
无效:经治疗后症状、体征无改善。
本发明治疗结果如下:
本发明采用中药汤剂治疗鼻炎患者56例、鼻窦炎患者39例。按照常规中药汤剂的服用方法连续服用本发明药物,10天为一个疗程,一日三次服用;经连续服用三个疗程后,治愈82例,有效10例,无效3例,总有效率为96.84%。
典型病例列举:
病例1:
王某某,女,25岁,患鼻炎一年左右,晚上睡觉经常鼻塞,左侧躺着左边鼻子鼻塞,右侧躺右边鼻子鼻塞,嗓子有白痰吐不干净也咽不下去,经多方治疗无效。口服本发明药物三个疗程后,症状全部消失,后又巩固两个疗程。经检查各项指标正常,随访两年无复发。
病例2:
李某某,男,39岁,患鼻窦炎两年余,患者自述日常生活经常鼻塞、头痛、头晕、伴有涕多、嗅觉减退。也吃过中药、使用过喷剂,但是经常复发,给生活带来极大的不便。口服本发明药物三个疗程后,症状全部消失,后又巩固三个疗程。随访两年无复发。
病例3:
刘某某,男,45岁,患鼻炎十年余,患者自述吃过很多中药、西药,没有痊愈过,经常头疼、鼻塞、打喷嚏,影响了正常的生活和工作。口服本发明药物三个疗程后,症状消失,后又巩固三个疗程,随访两年无复发。
本发明的有益效果如下:
本发明不仅利肺开窍、清热解表、利水散瘀、醒脾升阳、化痰理气,而且价格低廉、不易复发、使用方便。
具体实施方式
以下结合实施例对本发明作进一步描述。
实施例1
所述的治疗鼻炎、鼻窦炎的中药组合物,由以下质量的中药原料制成:
石菖蒲6克,百合6克,山楂60克,木香30克,麻黄6克,金银花6克,连翘6克,决明子9克,桂枝6克,防风6克,荆芥6克,白芷6克,辛夷9克,苍耳子15克,陈皮9克,砂仁6克,白术9克,茯苓9克,薄荷3克,鸡血藤9克,川芎9克,红花6克,桔梗6克,麦冬6克。
实施例2
所述的治疗鼻炎、鼻窦炎的中药组合物,由以下质量的中药原料制成:
石菖蒲9克,百合9克,山楂55克,木香27克,麻黄4克,金银花8克,连翘8克,决明子12克,桂枝9克,防风9克,荆芥9克,白芷9克,辛夷12克,苍耳子12克,陈皮12克,砂仁9克,白术6克,茯苓6克,薄荷6克,鸡血藤10克,川芎10克,红花9克,桔梗9克,麦冬8克。

Claims (2)

1.一种治疗鼻炎、鼻窦炎的中药组合物,其特征在于由以下质量的中药原料制成:
石菖蒲6-9克,百合6-9克,山楂50-60克,木香27-33克,麻黄4-8克,金银花4-8克,连翘4-8克,决明子9-12克,桂枝6-9克,防风6-9克,荆芥6-9克,白芷6-9克,辛夷9-12克,苍耳子12-18克,陈皮9-12克,砂仁6-9克,白术6-9克,茯苓6-9克,薄荷2-6克,鸡血藤9-12克,川芎9-12克,红花6-9克,桔梗6-9克,麦冬6-9克。
2.根据权利要求1所述的治疗鼻炎、鼻窦炎的中药组合物,其特征在于由以下质量的中药原料制成:
石菖蒲6克,百合6克,山楂60克,木香30克,麻黄6克,金银花6克,连翘6克,决明子9克,桂枝6克,防风6克,荆芥6克,白芷6克,辛夷9克,苍耳子15克,陈皮9克,砂仁6克,白术9克,茯苓9克,薄荷3克,鸡血藤9克,川芎9克,红花6克,桔梗6克,麦冬6克。
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Cited By (5)

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CN104815284A (zh) * 2015-03-28 2015-08-05 繁昌县智融中药材专业合作社 一种治疗鼻息肉的中药组合物
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CN105435080A (zh) * 2016-01-04 2016-03-30 周善达 一种治疗鼻炎的药物组合物、其应用及制备方法
CN110201132A (zh) * 2019-05-30 2019-09-06 佟永利 一种用于治疗鼻炎的肚脐药贴及其制备方法

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