CN104257852B - A kind of Chinese medicine composition treating migraine - Google Patents

A kind of Chinese medicine composition treating migraine Download PDF

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CN104257852B
CN104257852B CN201410576348.5A CN201410576348A CN104257852B CN 104257852 B CN104257852 B CN 104257852B CN 201410576348 A CN201410576348 A CN 201410576348A CN 104257852 B CN104257852 B CN 104257852B
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medicine composition
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chinese medicine
migraine
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CN104257852A (en
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逄海东
逄海玲
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Haimen Dade Intellectual Property Services Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/14Cupressaceae (Cypress family), e.g. juniper or cypress
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/76Salicaceae (Willow family), e.g. poplar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles

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Abstract

The present invention discloses a kind of Chinese medicine composition treating migraine, is made up of the Chinese medicinal materials of following weight part: leaf of Punetree 50 ~ 100 parts, Cortex Populi Davidianae 20 ~ 40 parts, Twig of Mourning Cypress 2 ~ 8 parts, benbie 2 ~ 8 parts, Herba Moghaniae fruticulosa 2 ~ 8 parts, thesium Chinese turcz 1 ~ 3 part, Root of Smalleaf Desmodium 1 ~ 3 part, stem of Broadbean 1 ~ 3 part, Phtheirospermum tenuisectum Bur.et Franch. 1 ~ 3 part. By clinical application and observation, the invention has the beneficial effects as follows: be easy to absorption, instant effect, good effect, have no side effect, easy to use, price is low.

Description

A kind of Chinese medicine composition treating migraine
Technical field
The present invention relates to technical field of traditional Chinese medicines, specifically refer to a kind of Chinese medicine composition treating migraine.
Background technology
Migraine is one of clinical common headache type, and the traditional Chinese medical science is commonly called as " migraine ", and doctor trained in Western medicine claims vascular headache. Mainly shrinking because of entocranial artery or expand and cause, about 2/3 is the headache of side property, it is possible to for having a headache in two side. This disease is not to accompany the migraine of tendency the most common: in outbreak property, degree is to severe pulsation or persistence headache, and the swollen pain in head side or two side, frequently shows effect, companion's Nausea and vomiting or photophobia. Migraine has the clear and definite normal clearance phase, and headache continues 4 ~ 72 hours, common alleviation after sleep.
In current existing technology, this disease of western medical treatment is normal based on sedation-analgesia, cures the symptoms, not the disease, and stomach is had stimulation by Western medicine, can produce bad side effect. The traditional Chinese medical science adopts traditional Chinese medicine for oral administration, the shortcoming generally existed be treatment time length, weak curative effect, expense big, effect is undesirable.
Summary of the invention
The present invention is in order to make up the deficiencies in the prior art, it provides a kind of instant effect, good effect, have no side effect, the Chinese medicine for the treatment of migraine that price is low. The present invention is achieved by the following technical solutions:
Treat a Chinese medicine composition for migraine, it is made up of the Chinese medicinal materials of following weight part: leaf of Punetree 50 ~ 100 parts, Cortex Populi Davidianae 20 ~ 40 parts, Twig of Mourning Cypress 2 ~ 8 parts, benbie 2 ~ 8 parts, Herba Moghaniae fruticulosa 2 ~ 8 parts, thesium Chinese turcz 1 ~ 3 part, Root of Smalleaf Desmodium 1 ~ 3 part, stem of Broadbean 1 ~ 3 part, Phtheirospermum tenuisectum Bur.et Franch. 1 ~ 3 part.
Preferably, treat a Chinese medicine composition for migraine, it is made up of the Chinese medicinal materials of following weight part: leaf of Punetree 75 parts, Cortex Populi Davidianae 30 parts, Twig of Mourning Cypress 5 parts, benbie 5 parts, Herba Moghaniae fruticulosa 5 parts, thesium Chinese turcz 2 parts, Root of Smalleaf Desmodium 2 parts, stem of Broadbean 2 parts, Phtheirospermum tenuisectum Bur.et Franch. 2 parts.
Leaf of Punetree: [source] is the leaf of the white thousand thing Punetrees of myrtle. [function cures mainly] wind-expelling pain-stopping; Profit is wet antipruritic. Main cold, fever; Treating rheumatic ostealgia; Stomachache is had loose bowels; Rubella; Temperature rash.
Cortex Populi Davidianae: [source] is the bark of dicotyledons medicine Salicaceae plant aspen. [function cures mainly] expelling wind and activating blood circulation; Clearing heat and promoting diuresis; Expelling parasite. Main wandering arthritis; Beriberi; Flutter damage hemostasis; Dysentery; Cough due to lung-heat; Aphtha; Toothache;Dribbling urination; Ascariasis.
Twig of Mourning Cypress: [source] is the branches and leaves of Cupressaceae plant cypress. [function cures mainly] cooling blood for hemostasis; Expelling pus and promoting granulation. Main haematemesis; Bloody flux; Hemorrhoid; Impetigo; Scald; Knife wound; Venomous snake bite.
Benbie: the full grass that [source] is labiate benbie. [function cures mainly] is promoting blood circulation and removing obstruction in channels; Detoxify and promote the subsdence of swelling. Main wound; Arthralgia and myalgia; Numbness of the limbs; Hemiplegia; Face is completed; Jaundice; Nasosinusitis; Scrofula; Swollen poison; Impetigo.
Herba Moghaniae fruticulosa: [source] is the root of leguminous plants subshrub Root of Philippine Flemingia. [function cures mainly] removing heat-phlegm; Eliminating dampness and dredging channels; Strong spleen disappears infantile malnutrition due to digestive disturbances or intestinalparasites. Main cold, fever; Lung heat cough; Asthma; Whooping cough; Rheumatic arthralgia; Jaundice; Dysmenorrhoea; Infantile malnutrition; Diarrhoea; Maldigestion.
Thesium Chinese turcz: [source] is the full grass of santal section plant thesium Chinese turcz or its mutation length stalk thesium Chinese turcz. [function cures mainly] heat-clearing, profit are wet, removing toxic substances. Main common cold due to wind-heat, heatstroke, lung carbuncle, acute tonsillitis, tuberculous lymphadenitis, breast pain, furuncle swell, drench card, yellow subcutaneous ulcer, pain in the back, seminal emission.
Root of Smalleaf Desmodium: [source] is leguminous plants Herba desmodii microphylli grass DesmodiummicrophylLum(Thunb.) root of DC.. [function cures mainly] clearing heat and promoting diuresis; Relieving cough and asthma; Subduing swelling and detoxicating. Main urolithiasis; Stomachache; Jaundice; Dysentery; Cough; Asthma; Infantile malnutrition; Venomous snake bite; Carbuncle sore scrofula; Dermatitis rhus; Hemorrhoid.
Stem of Broadbean: [source] is the stem of leguminous plants broad bean ViciafabaL.. [function cures mainly] stops blooding; Antidiarrheal; Removing toxic substances sore. Main various internal hemorrhage; Watery diarrhea; Scald.
Phtheirospermum tenuisectum Bur.et Franch.: [source] is the full grass of goatweed grass analysis branch. [function cures mainly] falls apart the appropriate poison of the stasis of blood; Tranquilizing by nourishing the heart. Main fracture swells and ache; Cough; General middle band blood; Swelling and pain in the throat; Palpitaition god seized with terror; Snake lyssodexis.
The preparation method of the Chinese medicine composition of above-mentioned treatment migraine is: take each Chinese medicinal materials by above-mentioned weight part, pulverized into the fine powder of 100 order sieves, and mixed.
Methods for the treatment of: once a day, takes the Chinese medicine composition fine powder 2 ~ 3g of the present invention, adjusts into pasty state with 50 degree of white wine, is coated on the temple of pain side and keeps 30 minutes, then washes temple. Within 15 days, being 1 course for the treatment of, general 1 is taken effect or obviously take a turn for the better the course for the treatment of, and continuous 2 courses for the treatment of can fully recover.
The invention has the beneficial effects as follows: be easy to absorption, instant effect, good effect, have no side effect, easy to use, price is low.
Embodiment:
Below in conjunction with embodiment and case, the present invention is further illustrated.
Embodiment 1
Treat a Chinese medicine composition for migraine, it is made up of following Chinese medicinal materials: leaf of Punetree 50 parts, Cortex Populi Davidianae 40 parts, Twig of Mourning Cypress 2 parts, benbie 8 parts, Herba Moghaniae fruticulosa 2 parts, thesium Chinese turcz 3 parts, Root of Smalleaf Desmodium 1 part, stem of Broadbean 3 parts, Phtheirospermum tenuisectum Bur.et Franch. 1 part.
The preparation method of the Chinese medicine composition of above-mentioned treatment migraine is: take each Chinese medicinal materials by above-mentioned weight part, pulverized into the fine powder of 100 order sieves, and mixed.
Embodiment 2
Treat a Chinese medicine composition for migraine, it is made up of following Chinese medicinal materials: leaf of Punetree 100 parts, Cortex Populi Davidianae 20 parts, Twig of Mourning Cypress 8 parts, benbie 2 parts, Herba Moghaniae fruticulosa 8 parts, thesium Chinese turcz 1 part, Root of Smalleaf Desmodium 3 parts, stem of Broadbean 1 part, Phtheirospermum tenuisectum Bur.et Franch. 3 parts.
The preparation method of the Chinese medicine composition of above-mentioned treatment migraine is: take each Chinese medicinal materials by above-mentioned weight part, pulverized into the fine powder of 100 order sieves, and mixed.
Embodiment 3
Treat a Chinese medicine composition for migraine, it is made up of following Chinese medicinal materials: leaf of Punetree 75 parts, Cortex Populi Davidianae 30 parts, Twig of Mourning Cypress 5 parts, benbie 5 parts, Herba Moghaniae fruticulosa 5 parts, thesium Chinese turcz 2 parts, Root of Smalleaf Desmodium 2 parts, stem of Broadbean 2 parts, Phtheirospermum tenuisectum Bur.et Franch. 2 parts.
The preparation method of the Chinese medicine composition of above-mentioned treatment migraine is: take each Chinese medicinal materials by above-mentioned weight part, pulverized into the fine powder of 100 order sieves, and mixed.
Clinical trial data:
For inspection Chinese medicine composition of the present invention is to the result for the treatment of of migraine, choose Liuan City, Anhui Province Jinzhai County 114 example migraine patient, the range of age 21 ~ 69 years old, 41 years old mean age, the wherein male sex 58 example, women 56 example.
Case definition: a. has at least 5 outbreaks to meet b��d item standard. B. 4��72 hours Headache attacks time length (untreated or the person of failing to respond to any medical treatment). C. two at least had in features are had a headache: (1) is confined to single side; (2) beat character; (3) degree is middle degree or severe (daily limitation of activity or stopping); (4) because of go upstairs or other similar daily body movable and increase the weight of. D. have a headache the phase at least have following in one: (1) feel sick and/or vomiting; (2) photophobia and fearness sound. E. at least have following in one: (1) medical history, health check-up and neurologic check do not point out symptomatic headache; (2) medical history and/or health check-up and/or neurologic check point out symptomatic headache, but can be got rid of by suitable inspection; (3) performance having symptomatic headache, but migraine First-episode and symptomatic headache are in time without definite relation.
By random for above-mentioned 114 example migraine patients, be equally divided into three groups and carry out clinical observation treatment, often organize 38 example patients. Treatment group 1 adopts the traditional Chinese medicine composition for treating of the embodiment of the present invention 1, and treatment group 2 adopts the traditional Chinese medicine composition for treating of the embodiment of the present invention 2, and treatment group 3 adopts the traditional Chinese medicine composition for treating of the embodiment of the present invention 3.
Methods for the treatment of: once a day, takes the Chinese medicine composition fine powder 2 ~ 3g of the present invention, adjusts into pasty state with 50 degree of white wine, is coated on the temple of pain side and keeps 30 minutes, then washes temple. Within 15 days, being 1 course for the treatment of, treatment adds up result for the treatment of after 2 courses for the treatment of continuously.
Efficacy assessment standard:
Cure: clinical symptom disappearance.
Effective: clinical symptom obviously takes a turn for the better or takes a turn for the better.
Invalid: clinical symptom is compared without improvement with before treatment.
Result for the treatment of:
Treatment group 1: cure 9 examples; Effective 27 examples; Invalid 2 examples; Always there is efficiency 94.7%; In process of the test, find no any untoward reaction.
Treatment group 2: cure 15 examples; Effective 23 examples; Invalid 0 example; Always there is efficiency 100%; In process of the test, find no any untoward reaction.
Treatment group 3: cure 25 examples; Effective 13 examples; Invalid 0 example; Always there is efficiency 100%; In process of the test, find no any untoward reaction.
From above-mentioned result for the treatment of it may be seen that the Chinese medicine composition of the present invention's three embodiments all has the curative effect of well treatment migraine, efficiency is always had to reach more than 94.7%, wherein, the curative ratio of the Chinese medicine composition of embodiment 3 is the highest, reaches 65.8%, achieves unexpected effect.

Claims (2)

1. treat the Chinese medicine composition of migraine for one kind, it is characterised in that: it is made up of the Chinese medicinal materials of following weight part: leaf of Punetree 50��100 parts, Cortex Populi Davidianae 20��40 parts, Twig of Mourning Cypress 2��8 parts, benbie 2��8 parts, Herba Moghaniae fruticulosa 2��8 parts, thesium Chinese turcz 1��3 part, Root of Smalleaf Desmodium 1��3 part, stem of Broadbean 1��3 part, Phtheirospermum tenuisectum Bur.et Franch. 1��3 part;Preparation method is: take each Chinese medicinal materials by above-mentioned weight part, pulverized into the fine powder of 100 order sieves, and mixed, adjust into pasty state with 50 degree of white wine.
2. a kind of Chinese medicine composition treating migraine according to claim 1, it is characterised in that: it is made up of the Chinese medicinal materials of following weight part: leaf of Punetree 75 parts, Cortex Populi Davidianae 30 parts, Twig of Mourning Cypress 5 parts, benbie 5 parts, Herba Moghaniae fruticulosa 5 parts, thesium Chinese turcz 2 parts, Root of Smalleaf Desmodium 2 parts, stem of Broadbean 2 parts, Phtheirospermum tenuisectum Bur.et Franch. 2 parts.
CN201410576348.5A 2014-10-26 2014-10-26 A kind of Chinese medicine composition treating migraine Active CN104257852B (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101288715A (en) * 2008-05-15 2008-10-22 胡彩芳 Orally-taken Chinese medicine for treating headache due to wind-heat evil
CN101306088A (en) * 2008-06-03 2008-11-19 凌志贤 Chinese traditional medicine taken orally for treating intercostal meuralgia
CN103393819A (en) * 2013-08-19 2013-11-20 李金领 Mouthwash

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101288715A (en) * 2008-05-15 2008-10-22 胡彩芳 Orally-taken Chinese medicine for treating headache due to wind-heat evil
CN101306088A (en) * 2008-06-03 2008-11-19 凌志贤 Chinese traditional medicine taken orally for treating intercostal meuralgia
CN103393819A (en) * 2013-08-19 2013-11-20 李金领 Mouthwash

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